GOLGA2P10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1planar cell polarity pathway involved in neural tube closure (GO:0090179)5.17151659
2regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)4.91293553
3axonemal dynein complex assembly (GO:0070286)4.37359738
4establishment of planar polarity (GO:0001736)4.10865418
5establishment of tissue polarity (GO:0007164)4.10865418
6motile cilium assembly (GO:0044458)3.91372363
7paraxial mesoderm development (GO:0048339)3.78435611
8G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071993.69613392
9establishment of apical/basal cell polarity (GO:0035089)3.69344862
10lateral sprouting from an epithelium (GO:0060601)3.64297707
11convergent extension (GO:0060026)3.54978105
12Wnt signaling pathway, planar cell polarity pathway (GO:0060071)3.53906044
13nucleosome disassembly (GO:0006337)3.53763361
14protein-DNA complex disassembly (GO:0032986)3.53763361
15cell migration in hindbrain (GO:0021535)3.48934775
16regulation of establishment of planar polarity (GO:0090175)3.45263963
17establishment of monopolar cell polarity (GO:0061162)3.36517144
18establishment or maintenance of monopolar cell polarity (GO:0061339)3.36517144
19cilium or flagellum-dependent cell motility (GO:0001539)3.34147679
20heterochromatin organization (GO:0070828)3.33604391
21camera-type eye morphogenesis (GO:0048593)3.28384218
22epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.25481476
23cilium movement (GO:0003341)3.24388631
24cochlea morphogenesis (GO:0090103)3.16082812
25pyrimidine nucleobase catabolic process (GO:0006208)3.11514020
26RNA localization (GO:0006403)3.09103685
27establishment or maintenance of apical/basal cell polarity (GO:0035088)3.00910087
28establishment or maintenance of bipolar cell polarity (GO:0061245)3.00910087
29establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.99205240
30lung epithelium development (GO:0060428)2.97909115
31apical protein localization (GO:0045176)2.97722452
32non-canonical Wnt signaling pathway (GO:0035567)2.97250677
33epithelial cilium movement (GO:0003351)2.94199259
34embryonic camera-type eye development (GO:0031076)2.84821645
35dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.78188952
36lens fiber cell development (GO:0070307)2.75530772
37layer formation in cerebral cortex (GO:0021819)2.74238078
38body morphogenesis (GO:0010171)2.73793685
39mRNA stabilization (GO:0048255)2.73786331
40RNA stabilization (GO:0043489)2.73786331
41polarized epithelial cell differentiation (GO:0030859)2.71985419
42embryonic body morphogenesis (GO:0010172)2.69604339
43positive regulation of smoothened signaling pathway (GO:0045880)2.67891503
44neuron projection extension involved in neuron projection guidance (GO:1902284)2.67638060
45axon extension involved in axon guidance (GO:0048846)2.67638060
46renal system development (GO:0072001)2.61465633
47establishment of mitochondrion localization (GO:0051654)2.58753984
48regulation of posttranscriptional gene silencing (GO:0060147)2.58487989
49regulation of gene silencing by miRNA (GO:0060964)2.58487989
50regulation of gene silencing by RNA (GO:0060966)2.58487989
51asymmetric protein localization (GO:0008105)2.58157231
52semaphorin-plexin signaling pathway (GO:0071526)2.54748521
53regulation of translational fidelity (GO:0006450)2.52197283
54negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.52078386
55histone H3-K36 demethylation (GO:0070544)2.51070518
56peptidyl-arginine N-methylation (GO:0035246)2.50754022
57peptidyl-arginine methylation (GO:0018216)2.50754022
58notochord development (GO:0030903)2.50165565
59histone H3-K9 demethylation (GO:0033169)2.49958723
60histone lysine demethylation (GO:0070076)2.48989764
61post-anal tail morphogenesis (GO:0036342)2.45586043
62establishment of spindle orientation (GO:0051294)2.44856135
63negative regulation of histone methylation (GO:0031061)2.44708002
64hemidesmosome assembly (GO:0031581)2.44558532
65neuronal stem cell maintenance (GO:0097150)2.44062447
66establishment of spindle localization (GO:0051293)2.43210822
67coronary vasculature morphogenesis (GO:0060977)2.43183388
68axonal fasciculation (GO:0007413)2.42234746
69left/right pattern formation (GO:0060972)2.40983515
70stress granule assembly (GO:0034063)2.40877097
71eye morphogenesis (GO:0048592)2.38696123
72regulation of RNA export from nucleus (GO:0046831)2.36875396
73regulation of chromatin binding (GO:0035561)2.35939669
74establishment of nucleus localization (GO:0040023)2.35050601
75regulation of NFAT protein import into nucleus (GO:0051532)2.34080852
76histone demethylation (GO:0016577)2.34016726
77positive regulation of dendritic spine morphogenesis (GO:0061003)2.33200112
78neuron recognition (GO:0008038)2.32932433
79gap junction assembly (GO:0016264)2.31857791
80DNA topological change (GO:0006265)2.31248102
81mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)2.30895962
82mating behavior (GO:0007617)2.30669348
83ear development (GO:0043583)2.30646376
84establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.29868565
85mitochondrion transport along microtubule (GO:0047497)2.29868565
86nuclear pore complex assembly (GO:0051292)2.29634299
87spliceosomal tri-snRNP complex assembly (GO:0000244)2.29361860
88establishment of mitotic spindle localization (GO:0040001)2.29235962
89dorsal/ventral axis specification (GO:0009950)2.29138789
90embryonic retina morphogenesis in camera-type eye (GO:0060059)2.28703355
91peptidyl-arginine omega-N-methylation (GO:0035247)2.27776304
92establishment of mitotic spindle orientation (GO:0000132)2.27632431
93endothelial cell chemotaxis (GO:0035767)2.26613655
94regulation of mRNA stability (GO:0043488)2.26442253
95nucleobase catabolic process (GO:0046113)2.25004758
96chromatin assembly (GO:0031497)2.23779373
97regulation of stem cell maintenance (GO:2000036)2.23272031
98axon extension (GO:0048675)2.22594301
99calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.22287603
100pre-miRNA processing (GO:0031054)2.21298849

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.49517660
2RBPJ_22232070_ChIP-Seq_NCS_Mouse4.18743341
3TP63_17297297_ChIP-ChIP_HaCaT_Human3.06234830
4ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.80372424
5FOXM1_23109430_ChIP-Seq_U2OS_Human2.70858683
6ZNF263_19887448_ChIP-Seq_K562_Human2.66093725
7NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.38734173
8EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.32260749
9CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.23255068
10ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.20812498
11ESR1_15608294_ChIP-ChIP_MCF-7_Human2.18111417
12ERG_21242973_ChIP-ChIP_JURKAT_Human2.15788384
13ZFP281_18757296_ChIP-ChIP_E14_Mouse2.14470108
14HIF1A_21447827_ChIP-Seq_MCF-7_Human1.98848081
15WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.90613709
16EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.76363806
17EZH2_22144423_ChIP-Seq_EOC_Human1.74410341
18MYC_22102868_ChIP-Seq_BL_Human1.72857911
19CLOCK_20551151_ChIP-Seq_293T_Human1.72652672
20CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.71042171
21RACK7_27058665_Chip-Seq_MCF-7_Human1.69894673
22KDM2B_26808549_Chip-Seq_K562_Human1.69389015
23STAT6_21828071_ChIP-Seq_BEAS2B_Human1.64917903
24CREB1_26743006_Chip-Seq_LNCaP_Human1.62463536
25ZFP281_27345836_Chip-Seq_ESCs_Mouse1.60649976
26E2F7_22180533_ChIP-Seq_HELA_Human1.53658974
27SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.52604363
28TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.51794747
29TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.51333794
30POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.42957646
31CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.41806182
32CHD1_26751641_Chip-Seq_LNCaP_Human1.38614128
33LXR_22292898_ChIP-Seq_THP-1_Human1.35961498
34HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.35659490
35RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.35398783
36KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.35272046
37KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.35272046
38KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.35272046
39KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.33379284
40CTCF_27219007_Chip-Seq_Bcells_Human1.32549490
41TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.31728465
42OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.31515147
43EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.29659365
44KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.29325349
45RARG_19884340_ChIP-ChIP_MEFs_Mouse1.29273641
46AR_21909140_ChIP-Seq_LNCAP_Human1.29232176
47CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.28223991
48P300_27058665_Chip-Seq_ZR-75-30cells_Human1.27527718
49RUNX1_27514584_Chip-Seq_MCF-7_Human1.27353585
50KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.26799811
51KDM2B_26808549_Chip-Seq_SUP-B15_Human1.25556937
52CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.24876459
53ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.23899606
54MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.23132677
55KDM2B_26808549_Chip-Seq_DND41_Human1.23021412
56XRN2_22483619_ChIP-Seq_HELA_Human1.22418342
57PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.21205688
58UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.21118691
59SMC4_20622854_ChIP-Seq_HELA_Human1.21074671
60KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.20950060
61WT1_19549856_ChIP-ChIP_CCG9911_Human1.20353956
62CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.19768750
63ESR2_21235772_ChIP-Seq_MCF-7_Human1.18579538
64POU5F1_16518401_ChIP-PET_MESCs_Mouse1.18460630
65KDM2B_26808549_Chip-Seq_JURKAT_Human1.18414924
66NANOG_21062744_ChIP-ChIP_HESCs_Human1.17411203
67DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.17258888
68SOX2_18555785_ChIP-Seq_MESCs_Mouse1.17085943
69RING1B_27294783_Chip-Seq_NPCs_Mouse1.15402210
70DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.15365078
71KLF4_18555785_ChIP-Seq_MESCs_Mouse1.15118012
72TP63_19390658_ChIP-ChIP_HaCaT_Human1.13295516
73MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.13208062
74NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.12914884
75ELK3_25401928_ChIP-Seq_HUVEC_Human1.11429399
76TP53_22127205_ChIP-Seq_IMR90_Human1.10282098
77MYC_18555785_ChIP-Seq_MESCs_Mouse1.10068208
78TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.08904720
79EED_16625203_ChIP-ChIP_MESCs_Mouse1.08598413
80KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.07322931
81TP53_20018659_ChIP-ChIP_R1E_Mouse1.06938201
82EZH2_18974828_ChIP-Seq_MESCs_Mouse1.06366252
83RNF2_18974828_ChIP-Seq_MESCs_Mouse1.06366252
84CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.06015498
85FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.04685650
86EZH2_27304074_Chip-Seq_ESCs_Mouse1.04340045
87SOX9_24532713_ChIP-Seq_HFSC_Mouse1.02379905
88SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.00744985
89SOX3_22085726_ChIP-Seq_NPCs_Mouse0.99861605
90RING1B_27294783_Chip-Seq_ESCs_Mouse0.99373284
91KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.99167647
92SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.98494021
93SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.97727392
94SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.96684667
95FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.95946141
96ISL1_27105846_Chip-Seq_CPCs_Mouse0.95858230
97SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.95272310
98NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.95093037
99P68_20966046_ChIP-Seq_HELA_Human0.94776956
100RARB_27405468_Chip-Seq_BRAIN_Mouse0.94461886

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000566_synostosis3.49677242
2MP0004858_abnormal_nervous_system3.14091008
3MP0010030_abnormal_orbit_morphology2.87974023
4MP0000537_abnormal_urethra_morphology2.81275029
5MP0000579_abnormal_nail_morphology2.23712809
6MP0003122_maternal_imprinting2.13292727
7MP0003315_abnormal_perineum_morphology2.12018897
8MP0003890_abnormal_embryonic-extraembry2.00683948
9MP0010234_abnormal_vibrissa_follicle2.00330690
10MP0002822_catalepsy1.98977432
11MP0002249_abnormal_larynx_morphology1.93072382
12MP0005076_abnormal_cell_differentiation1.87618575
13MP0003705_abnormal_hypodermis_morpholog1.78291461
14MP0004133_heterotaxia1.77821467
15MP0001849_ear_inflammation1.77750381
16MP0000778_abnormal_nervous_system1.74557013
17MP0005499_abnormal_olfactory_system1.70079612
18MP0005394_taste/olfaction_phenotype1.70079612
19MP0000049_abnormal_middle_ear1.69157190
20MP0003937_abnormal_limbs/digits/tail_de1.69081758
21MP0001188_hyperpigmentation1.65526803
22MP0000678_abnormal_parathyroid_gland1.60139368
23MP0001299_abnormal_eye_distance/1.59194063
24MP0006292_abnormal_olfactory_placode1.57925085
25MP0003861_abnormal_nervous_system1.57887892
26MP0003938_abnormal_ear_development1.55799905
27MP0003878_abnormal_ear_physiology1.55748586
28MP0005377_hearing/vestibular/ear_phenot1.55748586
29MP0002697_abnormal_eye_size1.54341409
30MP0003385_abnormal_body_wall1.52008443
31MP0000762_abnormal_tongue_morphology1.51832722
32MP0003942_abnormal_urinary_system1.47162061
33MP0002233_abnormal_nose_morphology1.43019033
34MP0008789_abnormal_olfactory_epithelium1.42656861
35MP0001293_anophthalmia1.42071249
36MP0004197_abnormal_fetal_growth/weight/1.37177188
37MP0002653_abnormal_ependyma_morphology1.36425422
38MP0002084_abnormal_developmental_patter1.34627537
39MP0003119_abnormal_digestive_system1.34545586
40MP0002092_abnormal_eye_morphology1.33997667
41MP0002111_abnormal_tail_morphology1.32788276
42MP0005409_darkened_coat_color1.31800214
43MP0004272_abnormal_basement_membrane1.31088695
44MP0003755_abnormal_palate_morphology1.30538732
45MP0002085_abnormal_embryonic_tissue1.30473443
46MP0003693_abnormal_embryo_hatching1.28477884
47MP0005248_abnormal_Harderian_gland1.24933070
48MP0002116_abnormal_craniofacial_bone1.23385892
49MP0001730_embryonic_growth_arrest1.22897859
50MP0004859_abnormal_synaptic_plasticity1.22115713
51MP0000534_abnormal_ureter_morphology1.21185220
52MP0000428_abnormal_craniofacial_morphol1.20883492
53MP0004233_abnormal_muscle_weight1.18960884
54MP0000383_abnormal_hair_follicle1.18411030
55MP0002796_impaired_skin_barrier1.16832770
56MP0002098_abnormal_vibrissa_morphology1.15259317
57MP0003935_abnormal_craniofacial_develop1.14864601
58MP0005187_abnormal_penis_morphology1.14310261
59MP0002009_preneoplasia1.12952609
60MP0010678_abnormal_skin_adnexa1.11970083
61MP0009053_abnormal_anal_canal1.11649139
62MP0005257_abnormal_intraocular_pressure1.11389854
63MP0000955_abnormal_spinal_cord1.11290793
64MP0002234_abnormal_pharynx_morphology1.10378107
65MP0000432_abnormal_head_morphology1.09548811
66MP0003115_abnormal_respiratory_system1.09172066
67MP0001286_abnormal_eye_development1.07987332
68MP0005501_abnormal_skin_physiology1.07386366
69MP0002152_abnormal_brain_morphology1.06362039
70MP0003121_genomic_imprinting1.05411716
71MP0005623_abnormal_meninges_morphology1.05270129
72MP0000631_abnormal_neuroendocrine_gland1.05220800
73MP0002184_abnormal_innervation1.03673183
74MP0009672_abnormal_birth_weight1.03554710
75MP0004264_abnormal_extraembryonic_tissu1.03447169
76MP0001672_abnormal_embryogenesis/_devel1.02236383
77MP0005380_embryogenesis_phenotype1.02236383
78MP0002081_perinatal_lethality0.98608517
79MP0008932_abnormal_embryonic_tissue0.97809003
80MP0009703_decreased_birth_body0.97182756
81MP0009780_abnormal_chondrocyte_physiolo0.96873317
82MP0003984_embryonic_growth_retardation0.95970752
83MP0002089_abnormal_postnatal_growth/wei0.95185392
84MP0001984_abnormal_olfaction0.93247460
85MP0002088_abnormal_embryonic_growth/wei0.91631121
86MP0004270_analgesia0.90856990
87MP0001502_abnormal_circadian_rhythm0.90199298
88MP0003567_abnormal_fetal_cardiomyocyte0.89097729
89MP0001346_abnormal_lacrimal_gland0.89010573
90MP0002114_abnormal_axial_skeleton0.85068738
91MP0002877_abnormal_melanocyte_morpholog0.84398859
92MP0002932_abnormal_joint_morphology0.83158200
93MP0000462_abnormal_digestive_system0.83133702
94MP0002282_abnormal_trachea_morphology0.83075086
95MP0001697_abnormal_embryo_size0.81669766
96MP0003136_yellow_coat_color0.81190443
97MP0004811_abnormal_neuron_physiology0.80522287
98MP0003111_abnormal_nucleus_morphology0.79636612
99MP0000467_abnormal_esophagus_morphology0.78398550
100MP0003566_abnormal_cell_adhesion0.77238323

Predicted human phenotypes

RankGene SetZ-score
1Hyperacusis (HP:0010780)3.58598639
2High anterior hairline (HP:0009890)3.48473568
3Abnormal respiratory motile cilium morphology (HP:0005938)3.30040913
4Abnormal respiratory epithelium morphology (HP:0012253)3.30040913
5Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.25490482
6Chronic bronchitis (HP:0004469)3.02267471
7Abnormal respiratory motile cilium physiology (HP:0012261)2.99264940
8Abnormal ciliary motility (HP:0012262)2.95972389
9Bronchomalacia (HP:0002780)2.68898164
10Abnormality of the aortic arch (HP:0012303)2.67427343
11Rhinitis (HP:0012384)2.62366176
12Morphological abnormality of the middle ear (HP:0008609)2.57958297
13Dynein arm defect of respiratory motile cilia (HP:0012255)2.44382737
14Absent/shortened dynein arms (HP:0200106)2.44382737
15Cortical dysplasia (HP:0002539)2.36555721
16Vertebral arch anomaly (HP:0008438)2.29961283
17Neonatal short-limb short stature (HP:0008921)2.22100832
18Atelectasis (HP:0100750)2.21478587
19Renovascular hypertension (HP:0100817)2.20156175
20Insomnia (HP:0100785)2.20112888
21Turricephaly (HP:0000262)2.14254328
22Overriding aorta (HP:0002623)2.13857547
23Coronal craniosynostosis (HP:0004440)2.11852048
24Ulnar bowing (HP:0003031)2.11463941
25Aplasia involving bones of the upper limbs (HP:0009823)2.11254555
26Aplasia of the phalanges of the hand (HP:0009802)2.11254555
27Aplasia involving bones of the extremities (HP:0009825)2.11254555
28Elfin facies (HP:0004428)2.09796442
29Renal duplication (HP:0000075)2.05831891
30Abnormality of the calcaneus (HP:0008364)2.04983200
31Atrophic scars (HP:0001075)2.04887362
32Breast hypoplasia (HP:0003187)2.04396253
33Increased nuchal translucency (HP:0010880)1.97943517
34Bell-shaped thorax (HP:0001591)1.94078142
35Calcaneovalgus deformity (HP:0001848)1.93651964
36Abnormality of abdominal situs (HP:0011620)1.92859706
37Abdominal situs inversus (HP:0003363)1.92859706
38Spina bifida occulta (HP:0003298)1.91221749
39Pterygium (HP:0001059)1.90727265
40Esophageal atresia (HP:0002032)1.88635016
41Abnormality of nail color (HP:0100643)1.87509011
42Broad face (HP:0000283)1.87051136
43Shallow orbits (HP:0000586)1.78834778
44Abnormality of dentin (HP:0010299)1.78215835
45Cutaneous finger syndactyly (HP:0010554)1.77289005
46Bladder diverticulum (HP:0000015)1.76584275
47Bifid scrotum (HP:0000048)1.75765785
48Labial hypoplasia (HP:0000066)1.75046489
49Precocious puberty (HP:0000826)1.74756743
50Trigonocephaly (HP:0000243)1.74179240
51Breech presentation (HP:0001623)1.72841526
52Insidious onset (HP:0003587)1.72637010
53Termporal pattern (HP:0011008)1.72637010
54Bronchiectasis (HP:0002110)1.72475998
55Abnormality of the dental root (HP:0006486)1.69739809
56Taurodontia (HP:0000679)1.69739809
57Abnormality of permanent molar morphology (HP:0011071)1.69739809
58Cutaneous syndactyly (HP:0012725)1.69419835
59Reticulocytosis (HP:0001923)1.68697643
60Generalized hypotonia (HP:0001290)1.68599417
61Thin ribs (HP:0000883)1.68032613
62Deep palmar crease (HP:0006191)1.65557036
63Long palpebral fissure (HP:0000637)1.65409351
64Down-sloping shoulders (HP:0200021)1.64195414
65Hypoplastic female external genitalia (HP:0012815)1.61803543
66Scrotal hypoplasia (HP:0000046)1.61283823
67Choanal stenosis (HP:0000452)1.60581644
68Self-mutilation (HP:0000742)1.60484985
69Nasal polyposis (HP:0100582)1.59885607
70Hepatoblastoma (HP:0002884)1.58426597
71Aplasia/Hypoplasia of the sternum (HP:0006714)1.57506215
72Facial cleft (HP:0002006)1.56431976
73Deformed tarsal bones (HP:0008119)1.55386020
74Hammertoe (HP:0001765)1.54062987
75Abnormality of the salivary glands (HP:0010286)1.53301752
76Coarctation of aorta (HP:0001680)1.53039559
77Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.50585719
78Arnold-Chiari malformation (HP:0002308)1.50577827
79Patellar aplasia (HP:0006443)1.48631402
80Omphalocele (HP:0001539)1.48248052
81Poor coordination (HP:0002370)1.48061543
82Broad palm (HP:0001169)1.47948412
83Abnormality of molar (HP:0011077)1.47763773
84Abnormality of molar morphology (HP:0011070)1.47763773
85Flat acetabular roof (HP:0003180)1.47714110
86Dysmetric saccades (HP:0000641)1.46744301
87Patellar dislocation (HP:0002999)1.46396546
88Vitreoretinal degeneration (HP:0000655)1.46170027
89Broad distal phalanx of finger (HP:0009836)1.45892449
90Abnormality of the diencephalon (HP:0010662)1.45131630
91Deviation of the thumb (HP:0009603)1.43098168
92Proximal placement of thumb (HP:0009623)1.41683555
93Obsessive-compulsive behavior (HP:0000722)1.41633998
94Shawl scrotum (HP:0000049)1.41560130
95Polycystic kidney dysplasia (HP:0000113)1.41088606
96Flat cornea (HP:0007720)1.40934165
97Midline defect of the nose (HP:0004122)1.40815020
98Abnormality of the dental pulp (HP:0006479)1.39983035
99Infertility (HP:0000789)1.39523720
100Male infertility (HP:0003251)1.39471499

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EEF2K3.88762793
2TRIB33.55325514
3CDK123.45243997
4ICK2.83252845
5MAP3K102.76929643
6PKN22.74550528
7EPHA22.42138173
8EPHB22.41160914
9LATS12.38939657
10NTRK12.37803558
11NEK22.32194196
12MAPK152.30708174
13SIK22.16619411
14BCR2.13946558
15SMG11.86526159
16MAP3K91.85566447
17MARK11.80356032
18TNIK1.66980051
19SIK11.65973066
20LATS21.65264984
21EPHA31.57071283
22FGFR41.33812194
23PRKD31.28614477
24BRD41.28185934
25CDC71.27165705
26RIPK11.24492783
27MTOR1.24238500
28RPS6KB21.19455515
29NME11.18111984
30TTK1.17461450
31CAMK1G1.12060678
32MAP3K41.07537205
33PNCK1.06589785
34CAMK1D1.06359079
35NTRK21.06041185
36DYRK30.98771061
37RPS6KA40.95674077
38MAP2K70.92401285
39CASK0.91859526
40MAP3K70.91419376
41DYRK20.89109099
42CDK70.85568818
43MARK20.85197809
44SRPK10.85049600
45FGFR20.84602183
46EPHB10.82111485
47TLK10.82051073
48PDGFRA0.81427009
49KSR10.80285731
50RPS6KA20.79770955
51RET0.73460379
52MET0.71728900
53FGFR10.69591168
54MAPKAPK30.64694100
55MST1R0.64390607
56TYRO30.63705678
57PASK0.63482263
58PTK20.62562732
59MAP3K60.61417907
60KSR20.60949014
61LMTK20.59743163
62PTK60.59495198
63MKNK10.59385332
64PAK20.58215171
65CDK10.57167051
66MAP2K20.57101836
67WNK40.56651081
68PRKAA10.55978455
69CSNK1E0.55772122
70STK38L0.55148852
71DYRK1B0.54836222
72CDK20.53750676
73MAP3K130.53224518
74RPS6KA10.52478731
75MAP3K80.51900418
76AKT20.51302847
77RPS6KL10.50563649
78RPS6KC10.50563649
79TSSK60.50548321
80RPS6KB10.49540739
81BMX0.49403559
82RPS6KA60.46974218
83STK30.46882041
84PRKD20.46712616
85MOS0.45451421
86GSK3B0.44221056
87CHEK10.44044931
88MAP2K40.43990909
89TTN0.43561148
90SGK4940.43237644
91SGK2230.43237644
92CDK11A0.42323040
93PINK10.40503550
94ROCK20.40198360
95CDK40.39899019
96MAPK90.39258313
97STK240.37945872
98PRKDC0.37611705
99ARAF0.37455652
100ATR0.36883607

Predicted pathways (KEGG)

RankGene SetZ-score
1Butirosin and neomycin biosynthesis_Homo sapiens_hsa005243.38883195
2Basal cell carcinoma_Homo sapiens_hsa052172.47203867
3Hedgehog signaling pathway_Homo sapiens_hsa043402.00162181
4Hippo signaling pathway_Homo sapiens_hsa043901.87833267
5Axon guidance_Homo sapiens_hsa043601.87610549
6Adherens junction_Homo sapiens_hsa045201.83422966
7mRNA surveillance pathway_Homo sapiens_hsa030151.82035476
8Central carbon metabolism in cancer_Homo sapiens_hsa052301.77999240
9Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.74496152
10Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.72270521
11Notch signaling pathway_Homo sapiens_hsa043301.67085843
12Steroid biosynthesis_Homo sapiens_hsa001001.63751969
13Tight junction_Homo sapiens_hsa045301.60639887
14Thyroid cancer_Homo sapiens_hsa052161.54146284
15Endometrial cancer_Homo sapiens_hsa052131.53474532
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.51124080
17Biosynthesis of amino acids_Homo sapiens_hsa012301.49462070
18Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.44923068
19Wnt signaling pathway_Homo sapiens_hsa043101.40906374
20Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.33839885
21Fructose and mannose metabolism_Homo sapiens_hsa000511.27904412
22Phenylalanine metabolism_Homo sapiens_hsa003601.27229261
23Colorectal cancer_Homo sapiens_hsa052101.23491980
24Melanogenesis_Homo sapiens_hsa049161.22462163
25MicroRNAs in cancer_Homo sapiens_hsa052061.21660758
26Spliceosome_Homo sapiens_hsa030401.20320003
27Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.19104332
28AMPK signaling pathway_Homo sapiens_hsa041521.17020641
29ErbB signaling pathway_Homo sapiens_hsa040121.16288147
30Insulin signaling pathway_Homo sapiens_hsa049101.16177995
31Bladder cancer_Homo sapiens_hsa052191.13198152
32Chronic myeloid leukemia_Homo sapiens_hsa052201.10082697
33Lysine degradation_Homo sapiens_hsa003101.05845631
34Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.05076901
35Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.03920739
36Thyroid hormone signaling pathway_Homo sapiens_hsa049191.03311681
37Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.99852098
38mTOR signaling pathway_Homo sapiens_hsa041500.99664379
39RNA transport_Homo sapiens_hsa030130.99418745
40Prostate cancer_Homo sapiens_hsa052150.99022869
412-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.96142958
42ECM-receptor interaction_Homo sapiens_hsa045120.93166016
43Cell cycle_Homo sapiens_hsa041100.91399337
44Cyanoamino acid metabolism_Homo sapiens_hsa004600.90161113
45Renal cell carcinoma_Homo sapiens_hsa052110.89883698
46VEGF signaling pathway_Homo sapiens_hsa043700.87759780
47Gap junction_Homo sapiens_hsa045400.87009567
48Longevity regulating pathway - mammal_Homo sapiens_hsa042110.86862954
49Base excision repair_Homo sapiens_hsa034100.84634294
50Type II diabetes mellitus_Homo sapiens_hsa049300.82937965
51Proteoglycans in cancer_Homo sapiens_hsa052050.82502282
52Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.81991732
53Carbon metabolism_Homo sapiens_hsa012000.81150486
54Choline metabolism in cancer_Homo sapiens_hsa052310.78867733
55Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.77988567
56Pathways in cancer_Homo sapiens_hsa052000.75405090
57Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.75334017
58Neurotrophin signaling pathway_Homo sapiens_hsa047220.73807719
59Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.72722784
60Selenocompound metabolism_Homo sapiens_hsa004500.71982651
61Small cell lung cancer_Homo sapiens_hsa052220.68680665
62DNA replication_Homo sapiens_hsa030300.68665244
63Arginine biosynthesis_Homo sapiens_hsa002200.68547061
64Glucagon signaling pathway_Homo sapiens_hsa049220.68438857
65Prolactin signaling pathway_Homo sapiens_hsa049170.65257197
66Sulfur relay system_Homo sapiens_hsa041220.65230386
67Estrogen signaling pathway_Homo sapiens_hsa049150.64532129
68Cocaine addiction_Homo sapiens_hsa050300.63423119
69Non-small cell lung cancer_Homo sapiens_hsa052230.63355299
70Tyrosine metabolism_Homo sapiens_hsa003500.63309510
71Focal adhesion_Homo sapiens_hsa045100.62856139
72Circadian rhythm_Homo sapiens_hsa047100.62651434
73TGF-beta signaling pathway_Homo sapiens_hsa043500.62126232
74Rap1 signaling pathway_Homo sapiens_hsa040150.61489532
75AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.61086855
76One carbon pool by folate_Homo sapiens_hsa006700.60772835
77Nicotine addiction_Homo sapiens_hsa050330.60261472
78Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.60039656
79Melanoma_Homo sapiens_hsa052180.58137594
80Inositol phosphate metabolism_Homo sapiens_hsa005620.57961155
81Pancreatic cancer_Homo sapiens_hsa052120.57558401
82Dilated cardiomyopathy_Homo sapiens_hsa054140.56901265
83Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.55942316
84Glioma_Homo sapiens_hsa052140.54705737
85Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.54623489
86HIF-1 signaling pathway_Homo sapiens_hsa040660.54307440
87Alcoholism_Homo sapiens_hsa050340.53757385
88Pentose phosphate pathway_Homo sapiens_hsa000300.52335261
89Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.50512252
90Nucleotide excision repair_Homo sapiens_hsa034200.50321871
91Arginine and proline metabolism_Homo sapiens_hsa003300.49881771
92Dorso-ventral axis formation_Homo sapiens_hsa043200.49496675
93Acute myeloid leukemia_Homo sapiens_hsa052210.49438760
94GnRH signaling pathway_Homo sapiens_hsa049120.49437852
95Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.48090027
96Long-term depression_Homo sapiens_hsa047300.48062965
97PI3K-Akt signaling pathway_Homo sapiens_hsa041510.47622066
98Protein digestion and absorption_Homo sapiens_hsa049740.45774916
99Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.45771449
100Oocyte meiosis_Homo sapiens_hsa041140.44598148

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