GOLGA2P7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of cell size (GO:0045793)5.45810172
2planar cell polarity pathway involved in neural tube closure (GO:0090179)5.44293919
3axonemal dynein complex assembly (GO:0070286)5.14582469
4diaphragm development (GO:0060539)5.04656322
5positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)4.97346203
6regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)4.97003851
7skeletal muscle organ development (GO:0060538)4.91917697
8cellular protein complex localization (GO:0034629)4.67126448
9epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.56208634
10lateral sprouting from an epithelium (GO:0060601)4.42474333
11establishment of planar polarity (GO:0001736)4.24075128
12establishment of tissue polarity (GO:0007164)4.24075128
13protein complex localization (GO:0031503)4.06626277
14apical protein localization (GO:0045176)4.01906581
15mRNA stabilization (GO:0048255)3.97053273
16RNA stabilization (GO:0043489)3.97053273
17motile cilium assembly (GO:0044458)3.89730440
18establishment of apical/basal cell polarity (GO:0035089)3.84555285
19dichotomous subdivision of an epithelial terminal unit (GO:0060600)3.84386982
20regulation of low-density lipoprotein particle receptor biosynthetic process (GO:0045714)3.75295184
21cilium or flagellum-dependent cell motility (GO:0001539)3.68412782
22camera-type eye morphogenesis (GO:0048593)3.65727779
23cilium movement (GO:0003341)3.63960479
243-UTR-mediated mRNA stabilization (GO:0070935)3.58972414
25Wnt signaling pathway, planar cell polarity pathway (GO:0060071)3.47620500
26negative regulation of vascular permeability (GO:0043116)3.44871982
27regulation of stem cell maintenance (GO:2000036)3.36973789
28asymmetric protein localization (GO:0008105)3.35257164
29establishment or maintenance of monopolar cell polarity (GO:0061339)3.29792228
30establishment of monopolar cell polarity (GO:0061162)3.29792228
31regulation of establishment of planar polarity (GO:0090175)3.27386260
32regulation of NFAT protein import into nucleus (GO:0051532)3.24188201
33convergent extension (GO:0060026)3.22606544
34positive regulation of DNA-dependent DNA replication (GO:2000105)3.21713389
35heterochromatin organization (GO:0070828)3.19983739
36negative regulation of peptidyl-threonine phosphorylation (GO:0010801)3.19527754
37left/right pattern formation (GO:0060972)3.16657344
38myoblast fusion (GO:0007520)3.15660750
39regulation of intracellular estrogen receptor signaling pathway (GO:0033146)3.15528607
40establishment or maintenance of bipolar cell polarity (GO:0061245)3.14010162
41establishment or maintenance of apical/basal cell polarity (GO:0035088)3.14010162
42regulation of cholesterol biosynthetic process (GO:0045540)3.12672990
43regulation of mRNA stability (GO:0043488)3.05244641
44chromatin silencing (GO:0006342)3.02954531
45positive regulation of receptor biosynthetic process (GO:0010870)3.00363814
46epithelial cilium movement (GO:0003351)2.98624567
47lung epithelium development (GO:0060428)2.96275038
48paraxial mesoderm development (GO:0048339)2.94895452
49arginine catabolic process (GO:0006527)2.93924074
50negative regulation of cell size (GO:0045792)2.93675569
51adherens junction assembly (GO:0034333)2.93158726
52pre-miRNA processing (GO:0031054)2.92535807
53histone H3-K4 methylation (GO:0051568)2.91923662
54syncytium formation by plasma membrane fusion (GO:0000768)2.84682020
55non-canonical Wnt signaling pathway (GO:0035567)2.80333489
56adenine nucleotide transport (GO:0051503)2.79991964
57positive regulation of smoothened signaling pathway (GO:0045880)2.79159204
58regulation of RNA stability (GO:0043487)2.77483849
59nucleosome disassembly (GO:0006337)2.75704928
60protein-DNA complex disassembly (GO:0032986)2.75704928
61establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.74899841
62cytoskeletal anchoring at plasma membrane (GO:0007016)2.74067178
63regulation of translational fidelity (GO:0006450)2.71999978
64activation of MAPKKK activity (GO:0000185)2.70419494
65response to lipoprotein particle (GO:0055094)2.70064174
66pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174)2.67250064
67UMP metabolic process (GO:0046049)2.67250064
68pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173)2.67250064
69UMP biosynthetic process (GO:0006222)2.67250064
70desmosome organization (GO:0002934)2.64949887
71positive regulation of cell cycle checkpoint (GO:1901978)2.63527406
72semaphorin-plexin signaling pathway (GO:0071526)2.54630641
73eye morphogenesis (GO:0048592)2.53828711
74negative regulation of gene expression, epigenetic (GO:0045814)2.49457126
75notochord development (GO:0030903)2.45376922
76pyrimidine nucleoside salvage (GO:0043097)2.45313087
77pyrimidine-containing compound salvage (GO:0008655)2.45313087
78embryonic camera-type eye development (GO:0031076)2.44046251
79DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.43985519
80DNA unwinding involved in DNA replication (GO:0006268)2.43092337
81axon extension involved in axon guidance (GO:0048846)2.43042428
82neuron projection extension involved in neuron projection guidance (GO:1902284)2.43042428
83pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.42851258
84regulation of cell size (GO:0008361)2.42126081
85neural tube development (GO:0021915)2.41620366
86DNA damage response, signal transduction resulting in transcription (GO:0042772)2.37417047
87negative regulation of neurotransmitter transport (GO:0051589)2.37153775
88branching involved in salivary gland morphogenesis (GO:0060445)2.36731953
89cochlea morphogenesis (GO:0090103)2.36373010
90negative regulation of potassium ion transmembrane transporter activity (GO:1901017)2.35612255
91exogenous drug catabolic process (GO:0042738)2.35376337
92syncytium formation (GO:0006949)2.33388193
93negative regulation of potassium ion transport (GO:0043267)2.33128135
94focal adhesion assembly (GO:0048041)2.33082867
95cell-substrate adherens junction assembly (GO:0007045)2.33082867
96regulation of nuclear cell cycle DNA replication (GO:0033262)2.30238942
97ribosomal small subunit assembly (GO:0000028)2.28202472
98negative regulation of potassium ion transmembrane transport (GO:1901380)2.27987182
99regulation of cilium assembly (GO:1902017)2.27775281
100epithelial cell-cell adhesion (GO:0090136)2.26162027

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.29501582
2E2F7_22180533_ChIP-Seq_HELA_Human3.35575639
3EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse3.00595665
4FOXM1_23109430_ChIP-Seq_U2OS_Human2.56366314
5TFAP2C_20629094_ChIP-Seq_MCF-7_Human2.54069456
6TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.52421577
7MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.42105002
8STAT6_21828071_ChIP-Seq_BEAS2B_Human2.35250956
9KDM2B_26808549_Chip-Seq_K562_Human2.31792713
10ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.30748145
11TP63_17297297_ChIP-ChIP_HaCaT_Human2.27968745
12LXR_22292898_ChIP-Seq_THP-1_Human2.12357294
13ZNF263_19887448_ChIP-Seq_K562_Human2.10473747
14ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.04457800
15RACK7_27058665_Chip-Seq_MCF-7_Human2.02128810
16SMC4_20622854_ChIP-Seq_HELA_Human2.01743272
17ERG_21242973_ChIP-ChIP_JURKAT_Human1.98524319
18ZFP281_18757296_ChIP-ChIP_E14_Mouse1.97128093
19ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.94660032
20WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.86060812
21RUNX1_27514584_Chip-Seq_MCF-7_Human1.82948361
22ESR2_21235772_ChIP-Seq_MCF-7_Human1.80897560
23ZFP281_27345836_Chip-Seq_ESCs_Mouse1.77567459
24MYC_22102868_ChIP-Seq_BL_Human1.75793959
25KDM2B_26808549_Chip-Seq_SUP-B15_Human1.74886116
26CREB1_26743006_Chip-Seq_LNCaP_Human1.70503711
27DROSHA_22980978_ChIP-Seq_HELA_Human1.66377382
28TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.65848530
29EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.62612488
30KDM2B_26808549_Chip-Seq_DND41_Human1.61928447
31ESR1_15608294_ChIP-ChIP_MCF-7_Human1.57291836
32KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.54818968
33SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.54550041
34KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.52693577
35ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.48400666
36ELK3_25401928_ChIP-Seq_HUVEC_Human1.46510534
37P68_20966046_ChIP-Seq_HELA_Human1.46124001
38DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.40203294
39MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.38572222
40TCF7_22412390_ChIP-Seq_EML_Mouse1.36811325
41CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.35479402
42ESR1_20079471_ChIP-ChIP_T-47D_Human1.33955290
43TET1_21451524_ChIP-Seq_MESCs_Mouse1.33885128
44TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.33232733
45P300_27058665_Chip-Seq_ZR-75-30cells_Human1.33148559
46KDM2B_26808549_Chip-Seq_JURKAT_Human1.32318683
47AR_21909140_ChIP-Seq_LNCAP_Human1.32068991
48CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.31432764
49TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.29087679
50CHD1_26751641_Chip-Seq_LNCaP_Human1.28806875
51SA1_27219007_Chip-Seq_ERYTHROID_Human1.28409947
52RARG_19884340_ChIP-ChIP_MEFs_Mouse1.26909488
53FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.26286266
54SOX9_24532713_ChIP-Seq_HFSC_Mouse1.25615826
55RING1B_27294783_Chip-Seq_NPCs_Mouse1.24586326
56NANOG_21062744_ChIP-ChIP_HESCs_Human1.23087558
57TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.22666325
58KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.21661011
59CTCF_27219007_Chip-Seq_Bcells_Human1.19959790
60CLOCK_20551151_ChIP-Seq_293T_Human1.17351065
61CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.15813289
62UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.15604127
63KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.15431959
64EZH2_27304074_Chip-Seq_ESCs_Mouse1.14820511
65HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.14328012
66RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.13752697
67DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.13749600
68ISL1_27105846_Chip-Seq_CPCs_Mouse1.13431120
69TP53_22127205_ChIP-Seq_IMR90_Human1.13107890
70KLF4_18555785_ChIP-Seq_MESCs_Mouse1.12944981
71HIF1A_21447827_ChIP-Seq_MCF-7_Human1.12720586
72NFIB_24661679_ChIP-Seq_LUNG_Mouse1.11718263
73XRN2_22483619_ChIP-Seq_HELA_Human1.08312614
74KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.08194637
75VDR_21846776_ChIP-Seq_THP-1_Human1.08068758
76EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.07898771
77RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.06293108
78ESR1_21235772_ChIP-Seq_MCF-7_Human1.06148804
79POU5F1_16518401_ChIP-PET_MESCs_Mouse1.05177463
80RNF2_18974828_ChIP-Seq_MESCs_Mouse1.04842711
81EZH2_18974828_ChIP-Seq_MESCs_Mouse1.04842711
82POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.04750014
83SOX2_27498859_Chip-Seq_STOMACH_Mouse1.04697728
84NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.03149727
85SOX3_22085726_ChIP-Seq_NPCs_Mouse1.02353485
86KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.02022306
87MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.00266963
88RNF2_27304074_Chip-Seq_ESCs_Mouse0.99854039
89CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.99707212
90KLF5_25053715_ChIP-Seq_YYC3_Human0.99442059
91GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.99317098
92STAT3_1855785_ChIP-Seq_MESCs_Mouse0.98597242
93SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.98447261
94TP63_22573176_ChIP-Seq_HFKS_Human0.97563051
95OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.97308830
96EZH2_27294783_Chip-Seq_ESCs_Mouse0.97290357
97JARID2_20075857_ChIP-Seq_MESCs_Mouse0.96594845
98SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.96182761
99SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.95981930
100ZFX_18555785_ChIP-Seq_MESCs_Mouse0.95427138

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000566_synostosis6.58002679
2MP0004858_abnormal_nervous_system3.91607194
3MP0004233_abnormal_muscle_weight3.12643158
4MP0000537_abnormal_urethra_morphology3.06367423
5MP0002234_abnormal_pharynx_morphology2.92872325
6MP0009053_abnormal_anal_canal2.62997675
7MP0010030_abnormal_orbit_morphology2.62432596
8MP0005076_abnormal_cell_differentiation2.51853199
9MP0003646_muscle_fatigue2.46132043
10MP0002249_abnormal_larynx_morphology2.35142256
11MP0004043_abnormal_pH_regulation2.34932946
12MP0003942_abnormal_urinary_system1.82684140
13MP0003705_abnormal_hypodermis_morpholog1.82558142
14MP0003937_abnormal_limbs/digits/tail_de1.81843822
15MP0002233_abnormal_nose_morphology1.81061109
16MP0010234_abnormal_vibrissa_follicle1.75681352
17MP0010368_abnormal_lymphatic_system1.75054550
18MP0000733_abnormal_muscle_development1.71510087
19MP0000467_abnormal_esophagus_morphology1.70898883
20MP0003283_abnormal_digestive_organ1.65433474
21MP0000579_abnormal_nail_morphology1.64674561
22MP0002009_preneoplasia1.55047378
23MP0002116_abnormal_craniofacial_bone1.46950898
24MP0005645_abnormal_hypothalamus_physiol1.46632271
25MP0001346_abnormal_lacrimal_gland1.43805715
26MP0000534_abnormal_ureter_morphology1.42223843
27MP0004133_heterotaxia1.41764369
28MP0003123_paternal_imprinting1.40926592
29MP0005623_abnormal_meninges_morphology1.35343645
30MP0009672_abnormal_birth_weight1.32862473
31MP0002084_abnormal_developmental_patter1.31952610
32MP0000432_abnormal_head_morphology1.30920887
33MP0005409_darkened_coat_color1.30405388
34MP0000428_abnormal_craniofacial_morphol1.27475041
35MP0000383_abnormal_hair_follicle1.26786414
36MP0003861_abnormal_nervous_system1.24532554
37MP0002697_abnormal_eye_size1.23122382
38MP0005394_taste/olfaction_phenotype1.22373962
39MP0005499_abnormal_olfactory_system1.22373962
40MP0001849_ear_inflammation1.21341730
41MP0000678_abnormal_parathyroid_gland1.20057843
42MP0002085_abnormal_embryonic_tissue1.19291081
43MP0003115_abnormal_respiratory_system1.19281780
44MP0010678_abnormal_skin_adnexa1.15925503
45MP0002111_abnormal_tail_morphology1.15603587
46MP0000762_abnormal_tongue_morphology1.15582314
47MP0003119_abnormal_digestive_system1.13761881
48MP0010307_abnormal_tumor_latency1.12376082
49MP0002098_abnormal_vibrissa_morphology1.10721498
50MP0003935_abnormal_craniofacial_develop1.10159136
51MP0003315_abnormal_perineum_morphology1.09904197
52MP0003938_abnormal_ear_development1.09659113
53MP0000049_abnormal_middle_ear1.05874137
54MP0004084_abnormal_cardiac_muscle1.05815533
55MP0000955_abnormal_spinal_cord1.05235472
56MP0002932_abnormal_joint_morphology1.05179584
57MP0005377_hearing/vestibular/ear_phenot1.04247887
58MP0003878_abnormal_ear_physiology1.04247887
59MP0008789_abnormal_olfactory_epithelium1.04045902
60MP0005380_embryogenesis_phenotype1.01852716
61MP0001672_abnormal_embryogenesis/_devel1.01852716
62MP0003755_abnormal_palate_morphology1.00377299
63MP0003693_abnormal_embryo_hatching0.99924571
64MP0003385_abnormal_body_wall0.98629838
65MP0003984_embryonic_growth_retardation0.96516181
66MP0006138_congestive_heart_failure0.95627596
67MP0009703_decreased_birth_body0.93907683
68MP0004264_abnormal_extraembryonic_tissu0.92791983
69MP0002088_abnormal_embryonic_growth/wei0.91198176
70MP0000778_abnormal_nervous_system0.90604698
71MP0002109_abnormal_limb_morphology0.89941093
72MP0001286_abnormal_eye_development0.88179985
73MP0002089_abnormal_postnatal_growth/wei0.86706093
74MP0005187_abnormal_penis_morphology0.85807762
75MP0004197_abnormal_fetal_growth/weight/0.85420415
76MP0003566_abnormal_cell_adhesion0.85387394
77MP0002114_abnormal_axial_skeleton0.83719311
78MP0009250_abnormal_appendicular_skeleto0.82898315
79MP0004185_abnormal_adipocyte_glucose0.81695499
80MP0003111_abnormal_nucleus_morphology0.80942705
81MP0002184_abnormal_innervation0.80811570
82MP0001299_abnormal_eye_distance/0.80711392
83MP0000631_abnormal_neuroendocrine_gland0.80165464
84MP0002822_catalepsy0.80039689
85MP0002092_abnormal_eye_morphology0.79292254
86MP0005167_abnormal_blood-brain_barrier0.79104758
87MP0001664_abnormal_digestion0.79039618
88MP0002796_impaired_skin_barrier0.78195288
89MP0002080_prenatal_lethality0.78110135
90MP0010630_abnormal_cardiac_muscle0.77638620
91MP0004272_abnormal_basement_membrane0.77050993
92MP0001879_abnormal_lymphatic_vessel0.75804602
93MP0000350_abnormal_cell_proliferation0.74623823
94MP0002081_perinatal_lethality0.73834359
95MP0002086_abnormal_extraembryonic_tissu0.73626627
96MP0005257_abnormal_intraocular_pressure0.72533077
97MP0001697_abnormal_embryo_size0.71436159
98MP0003941_abnormal_skin_development0.71257589
99MP0003045_fibrosis0.71119959
100MP0002108_abnormal_muscle_morphology0.70551636

Predicted human phenotypes

RankGene SetZ-score
1Lip pit (HP:0100267)5.61115261
2Respiratory insufficiency due to defective ciliary clearance (HP:0200073)5.16732870
3Anal stenosis (HP:0002025)4.56604793
4Sparse lateral eyebrow (HP:0005338)4.50686155
5Abnormality of the fingertips (HP:0001211)4.35916814
6Chronic bronchitis (HP:0004469)3.89790188
7Abnormal respiratory epithelium morphology (HP:0012253)3.82843488
8Abnormal respiratory motile cilium morphology (HP:0005938)3.82843488
9Abnormal respiratory motile cilium physiology (HP:0012261)3.63653622
10Rhinitis (HP:0012384)3.49950496
11Depressed nasal tip (HP:0000437)3.45481609
12Intestinal fistula (HP:0100819)3.39106456
13Short 5th finger (HP:0009237)3.26423748
14Aplasia/Hypoplasia of the 5th finger (HP:0006262)3.02700602
15Dynein arm defect of respiratory motile cilia (HP:0012255)3.00073428
16Absent/shortened dynein arms (HP:0200106)3.00073428
17Abnormal ciliary motility (HP:0012262)2.99089742
18Aplasia involving bones of the extremities (HP:0009825)2.83775383
19Aplasia involving bones of the upper limbs (HP:0009823)2.83775383
20Aplasia of the phalanges of the hand (HP:0009802)2.83775383
21Long palpebral fissure (HP:0000637)2.79419073
22Popliteal pterygium (HP:0009756)2.76195324
23Obstructive sleep apnea (HP:0002870)2.69389460
24Facial cleft (HP:0002006)2.62638476
25Ureteral stenosis (HP:0000071)2.62534333
26Hyperacusis (HP:0010780)2.57366637
27Abnormality of the distal phalanges of the toes (HP:0010182)2.56827034
28Dysmetric saccades (HP:0000641)2.52211668
29Periauricular skin pits (HP:0100277)2.50227251
30Preauricular pit (HP:0004467)2.50227251
31Self-mutilation (HP:0000742)2.47680024
32Turricephaly (HP:0000262)2.46723499
33Ectopic kidney (HP:0000086)2.44118565
34High anterior hairline (HP:0009890)2.41825713
35Natal tooth (HP:0000695)2.38935585
36Bronchiectasis (HP:0002110)2.35776215
37Ureteral obstruction (HP:0006000)2.35314326
38Pterygium (HP:0001059)2.35249583
39Shallow orbits (HP:0000586)2.29612571
40Recurrent otitis media (HP:0000403)2.29419348
41Asymmetry of the thorax (HP:0001555)2.25933690
42Broad thumb (HP:0011304)2.25484154
43Neonatal short-limb short stature (HP:0008921)2.22766096
44Skin pits (HP:0100276)2.20903015
45Abnormality of cochlea (HP:0000375)2.13459072
46Absent eyelashes (HP:0000561)2.10772680
47Aplasia/Hypoplasia of the vertebrae (HP:0008515)2.09607364
48Vertebral hypoplasia (HP:0008417)2.09607364
49Nasal polyposis (HP:0100582)2.07323426
50Abnormality of the aortic arch (HP:0012303)2.06262275
51Advanced eruption of teeth (HP:0006288)2.04661204
52Coarctation of aorta (HP:0001680)2.03376910
53Flat acetabular roof (HP:0003180)2.01786285
54Precocious puberty (HP:0000826)2.01104691
55Abnormal number of incisors (HP:0011064)2.00713558
56Atelectasis (HP:0100750)1.99815282
57Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.99318402
58Autoimmune thrombocytopenia (HP:0001973)1.98752090
59Broad phalanges of the hand (HP:0009768)1.94998079
60Preauricular skin tag (HP:0000384)1.92052058
61Broad face (HP:0000283)1.91606998
62Septate vagina (HP:0001153)1.90799686
63Absent eyebrow (HP:0002223)1.88972487
64Broad finger (HP:0001500)1.88162273
65Bifid scrotum (HP:0000048)1.86833932
66Cutaneous finger syndactyly (HP:0010554)1.84748991
67Preaxial foot polydactyly (HP:0001841)1.84330382
68Abnormality of the distal phalanx of the thumb (HP:0009617)1.83374068
69Broad hallux (HP:0010055)1.82184174
70Hypoplastic labia majora (HP:0000059)1.78967408
71Ulnar bowing (HP:0003031)1.76407218
72Cutaneous syndactyly (HP:0012725)1.74808289
73Narrow palate (HP:0000189)1.74239952
74Thin ribs (HP:0000883)1.72384520
75Mask-like facies (HP:0000298)1.71141439
76Disproportionate tall stature (HP:0001519)1.70877002
77Morphological abnormality of the inner ear (HP:0011390)1.70868546
78Uterine leiomyosarcoma (HP:0002891)1.70808851
79Leiomyosarcoma (HP:0100243)1.70808851
80Skin tags (HP:0010609)1.68662994
81Broad toe (HP:0001837)1.65875543
82Bronchomalacia (HP:0002780)1.64351630
83Broad distal phalanx of finger (HP:0009836)1.63372679
84Bell-shaped thorax (HP:0001591)1.63189118
85Abnormality of permanent molar morphology (HP:0011071)1.62493277
86Abnormality of the dental root (HP:0006486)1.62493277
87Taurodontia (HP:0000679)1.62493277
88Abnormality of the labia majora (HP:0012881)1.62488451
89Broad phalanx (HP:0006009)1.61343071
90Polycystic kidney dysplasia (HP:0000113)1.58344970
91Abnormal ventriculo-arterial connection (HP:0011563)1.56574510
92Transposition of the great arteries (HP:0001669)1.56574510
93Abnormal connection of the cardiac segments (HP:0011545)1.56574510
94Wide intermamillary distance (HP:0006610)1.55723438
95Partial duplication of thumb phalanx (HP:0009944)1.55646485
96Renal dysplasia (HP:0000110)1.54831612
97Abnormality of the phalanges of the hallux (HP:0010057)1.53978526
98Trismus (HP:0000211)1.53712636
99Congenital hip dislocation (HP:0001374)1.53511757
100Trigonocephaly (HP:0000243)1.52810184

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EEF2K6.03518962
2STK245.14158066
3TRIB33.87714106
4WNK43.06262491
5STK392.81376895
6MAP3K22.70353553
7MAP3K102.45055620
8CDK122.44081494
9ICK2.39970021
10EPHA22.28238800
11MAPK152.22707385
12SMG12.22398162
13CCNB12.21813700
14CAMK1G2.02367570
15MAPKAPK31.96809245
16MAP3K31.93826207
17ILK1.93482505
18CAMK1D1.90052955
19RPS6KB21.74567331
20TTK1.63831499
21SIK11.51804448
22PKN21.43835192
23CHEK21.38917246
24NTRK21.35806124
25CDC71.35614269
26PINK11.33432104
27MST1R1.32175838
28MTOR1.31787672
29WNK11.25102817
30RPS6KC11.18510503
31RPS6KL11.18510503
32PRKD31.08253063
33LATS21.07690949
34RPS6KA61.03870917
35RPS6KA21.03450933
36CAMK41.00901048
37LATS10.97851519
38PASK0.92011339
39FGFR40.90694694
40PNCK0.89554854
41MET0.87964681
42PDGFRA0.84904117
43RIPK10.84591401
44SRPK10.81788258
45NTRK10.78393473
46FGFR20.76127083
47MAPKAPK50.75446722
48BRD40.74300851
49CAMK10.73853748
50CAMKK10.67134972
51IRAK30.65457210
52CDK70.64057449
53NEK20.61537692
54MARK20.59750370
55PTK20.56405563
56CDK90.53646681
57NME10.53374799
58TRPM70.53094977
59TTN0.53039253
60TYRO30.51534978
61BMX0.51204266
62PRPF4B0.51130869
63JAK30.48358952
64CDK20.47161661
65EPHB20.46596899
66MELK0.44932947
67CDK10.42834839
68RET0.42543857
69RPS6KB10.41757014
70AKT20.40886223
71STK40.40392095
72PTK60.40380180
73CHEK10.40308004
74SIK20.39232936
75AKT30.36514144
76PAK40.36170980
77DYRK30.34892519
78PRKAA10.34743396
79MINK10.33823207
80CDK80.33180230
81AURKA0.33043428
82ERBB20.31584869
83ZAK0.31563404
84SGK2230.30811047
85SGK4940.30811047
86MAPK100.30767763
87CDC42BPA0.30762694
88WEE10.30127343
89MAP3K70.29551398
90MAPK90.29074139
91ATR0.29043434
92LMTK20.28271023
93GSK3B0.27691440
94DDR20.26502809
95MAPK110.25708233
96MAPK140.25239595
97RPS6KA10.22990066
98AKT10.22553250
99CSNK1A1L0.22249543
100CSNK1E0.21963363

Predicted pathways (KEGG)

RankGene SetZ-score
1Arginine biosynthesis_Homo sapiens_hsa002203.04859174
2Lysine degradation_Homo sapiens_hsa003102.71540496
3Basal cell carcinoma_Homo sapiens_hsa052172.13159862
4AMPK signaling pathway_Homo sapiens_hsa041522.08732990
5Hippo signaling pathway_Homo sapiens_hsa043901.92639488
6Notch signaling pathway_Homo sapiens_hsa043301.92578782
7Adherens junction_Homo sapiens_hsa045201.91971451
8mRNA surveillance pathway_Homo sapiens_hsa030151.85320940
9Cyanoamino acid metabolism_Homo sapiens_hsa004601.83030522
10Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.73242830
11Hedgehog signaling pathway_Homo sapiens_hsa043401.67537241
122-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.50166190
13Tight junction_Homo sapiens_hsa045301.44312721
14Insulin signaling pathway_Homo sapiens_hsa049101.44198554
15Biosynthesis of amino acids_Homo sapiens_hsa012301.44012616
16Phenylalanine metabolism_Homo sapiens_hsa003601.37279819
17Longevity regulating pathway - mammal_Homo sapiens_hsa042111.33887435
18Endometrial cancer_Homo sapiens_hsa052131.33442923
19Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.29938711
20Central carbon metabolism in cancer_Homo sapiens_hsa052301.29826837
21Thyroid hormone signaling pathway_Homo sapiens_hsa049191.26902100
22Melanogenesis_Homo sapiens_hsa049161.26376099
23Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.25728252
24Chronic myeloid leukemia_Homo sapiens_hsa052201.25519264
25Axon guidance_Homo sapiens_hsa043601.24677324
26Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.23839867
27mTOR signaling pathway_Homo sapiens_hsa041501.23507817
28MicroRNAs in cancer_Homo sapiens_hsa052061.21988169
29Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.21880138
30Glioma_Homo sapiens_hsa052141.19918747
31Thyroid cancer_Homo sapiens_hsa052161.17905527
32ErbB signaling pathway_Homo sapiens_hsa040121.15034861
33Wnt signaling pathway_Homo sapiens_hsa043101.09152874
34Prostate cancer_Homo sapiens_hsa052151.08147976
35Choline metabolism in cancer_Homo sapiens_hsa052311.05243546
36Arginine and proline metabolism_Homo sapiens_hsa003301.04840437
37Renal cell carcinoma_Homo sapiens_hsa052111.02565697
38ECM-receptor interaction_Homo sapiens_hsa045121.02326895
39Cell cycle_Homo sapiens_hsa041101.00533820
40Bladder cancer_Homo sapiens_hsa052190.99134166
41Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.98544851
42TGF-beta signaling pathway_Homo sapiens_hsa043500.97850331
43Neurotrophin signaling pathway_Homo sapiens_hsa047220.97783910
44Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.96954765
45Non-small cell lung cancer_Homo sapiens_hsa052230.94981352
46Small cell lung cancer_Homo sapiens_hsa052220.93716303
47Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.93045632
48N-Glycan biosynthesis_Homo sapiens_hsa005100.92671916
49Proteoglycans in cancer_Homo sapiens_hsa052050.89058891
50Colorectal cancer_Homo sapiens_hsa052100.87858210
51Vitamin B6 metabolism_Homo sapiens_hsa007500.86993365
52Dilated cardiomyopathy_Homo sapiens_hsa054140.85191144
53Estrogen signaling pathway_Homo sapiens_hsa049150.84325855
54Tyrosine metabolism_Homo sapiens_hsa003500.81950004
55DNA replication_Homo sapiens_hsa030300.80546972
56Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.79257450
57Focal adhesion_Homo sapiens_hsa045100.78768252
58VEGF signaling pathway_Homo sapiens_hsa043700.77949607
59Phosphatidylinositol signaling system_Homo sapiens_hsa040700.77527555
60Glucagon signaling pathway_Homo sapiens_hsa049220.75739498
61Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.75220767
62Fructose and mannose metabolism_Homo sapiens_hsa000510.74638326
63Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.74174067
64Alcoholism_Homo sapiens_hsa050340.71444206
65Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.70624915
66Aldosterone synthesis and secretion_Homo sapiens_hsa049250.70313951
67RNA transport_Homo sapiens_hsa030130.70091533
68Dopaminergic synapse_Homo sapiens_hsa047280.67379478
69Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.65644259
70Nucleotide excision repair_Homo sapiens_hsa034200.65556151
71Pathways in cancer_Homo sapiens_hsa052000.63731427
72Sulfur relay system_Homo sapiens_hsa041220.63561797
73One carbon pool by folate_Homo sapiens_hsa006700.63199609
74GnRH signaling pathway_Homo sapiens_hsa049120.61207470
75Circadian entrainment_Homo sapiens_hsa047130.60916195
76Long-term depression_Homo sapiens_hsa047300.60438415
77Pancreatic cancer_Homo sapiens_hsa052120.59546210
78Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.58931413
79Pentose phosphate pathway_Homo sapiens_hsa000300.58555994
80Inositol phosphate metabolism_Homo sapiens_hsa005620.56976358
81Sphingolipid signaling pathway_Homo sapiens_hsa040710.55929175
82Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.54577700
83Phospholipase D signaling pathway_Homo sapiens_hsa040720.53865441
84Gap junction_Homo sapiens_hsa045400.53487819
85Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.53316618
86Salivary secretion_Homo sapiens_hsa049700.52522582
87Drug metabolism - other enzymes_Homo sapiens_hsa009830.52081320
88Melanoma_Homo sapiens_hsa052180.51601408
89Rap1 signaling pathway_Homo sapiens_hsa040150.51376026
90Prion diseases_Homo sapiens_hsa050200.51061030
91Oxytocin signaling pathway_Homo sapiens_hsa049210.50682142
92Thyroid hormone synthesis_Homo sapiens_hsa049180.50213560
93Selenocompound metabolism_Homo sapiens_hsa004500.50077861
94Non-homologous end-joining_Homo sapiens_hsa034500.49805581
95Spliceosome_Homo sapiens_hsa030400.49404620
96Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.49346542
97Pyrimidine metabolism_Homo sapiens_hsa002400.46682200
98PI3K-Akt signaling pathway_Homo sapiens_hsa041510.46388997
99Histidine metabolism_Homo sapiens_hsa003400.45303953
100beta-Alanine metabolism_Homo sapiens_hsa004100.45198100

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »