GOLGA6C

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1chromosome condensation (GO:0030261)9.81261170
2single strand break repair (GO:0000012)9.56688243
3sperm capacitation (GO:0048240)9.45592455
4DNA packaging (GO:0006323)9.44048397
5spermatid nucleus differentiation (GO:0007289)8.63033842
6plasma membrane fusion (GO:0045026)8.13486013
7spermatid development (GO:0007286)7.53589603
8microtubule depolymerization (GO:0007019)7.51062662
9sperm-egg recognition (GO:0035036)7.46398943
10sexual reproduction (GO:0019953)7.21985090
11multicellular organism reproduction (GO:0032504)6.90207857
12binding of sperm to zona pellucida (GO:0007339)6.83786513
13reproduction (GO:0000003)6.74399377
14microtubule polymerization or depolymerization (GO:0031109)6.51918156
15axonemal dynein complex assembly (GO:0070286)6.37798197
16calcium ion-dependent exocytosis (GO:0017156)6.34874555
17protein targeting to Golgi (GO:0000042)6.34320589
18protein polyglutamylation (GO:0018095)6.33104304
19rRNA methylation (GO:0031167)6.29786173
20establishment of protein localization to Golgi (GO:0072600)6.16263654
21cell-cell recognition (GO:0009988)6.15459920
22antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G6.03293793
23centriole replication (GO:0007099)5.97619347
24spermatogenesis (GO:0007283)5.95972479
25male gamete generation (GO:0048232)5.94119613
26retrograde transport, vesicle recycling within Golgi (GO:0000301)5.88020580
27negative regulation of inclusion body assembly (GO:0090084)5.81833580
28phosphatidylethanolamine biosynthetic process (GO:0006646)5.76129686
29regulation of Rab GTPase activity (GO:0032313)5.71093535
30positive regulation of Rab GTPase activity (GO:0032851)5.71093535
31gamete generation (GO:0007276)5.42809351
32chromatin silencing (GO:0006342)5.39821027
33phosphatidylethanolamine metabolic process (GO:0046337)5.30186881
34rRNA modification (GO:0000154)5.23244936
35cellular ketone body metabolic process (GO:0046950)5.18499136
36microtubule severing (GO:0051013)5.12034971
37centriole assembly (GO:0098534)5.02015158
38motile cilium assembly (GO:0044458)5.00884656
39regulation of centriole replication (GO:0046599)4.83806823
40regulation of cilium movement (GO:0003352)4.74323707
41single fertilization (GO:0007338)4.70254864
42regulation of transcription involved in cell fate commitment (GO:0060850)4.59902903
43cilium or flagellum-dependent cell motility (GO:0001539)4.57927941
44ketone body metabolic process (GO:1902224)4.56123803
45protein localization to Golgi apparatus (GO:0034067)4.55289797
46germ cell development (GO:0007281)4.44821833
47multicellular organismal reproductive process (GO:0048609)4.32651750
48cell wall macromolecule metabolic process (GO:0044036)4.31421982
49cellular process involved in reproduction in multicellular organism (GO:0022412)4.30675644
50negative regulation of Rho protein signal transduction (GO:0035024)4.30125273
51cell wall macromolecule catabolic process (GO:0016998)4.27623780
52RNA destabilization (GO:0050779)4.19062943
53nucleus organization (GO:0006997)4.09426163
54regulation of inclusion body assembly (GO:0090083)4.08479277
55coenzyme catabolic process (GO:0009109)4.04905930
56seminiferous tubule development (GO:0072520)4.02483431
57fertilization (GO:0009566)3.95639069
58cartilage development involved in endochondral bone morphogenesis (GO:0060351)3.87135446
59epithelial cilium movement (GO:0003351)3.86117961
60negative regulation of gene expression, epigenetic (GO:0045814)3.65388176
61glycerol ether metabolic process (GO:0006662)3.63221363
62multicellular organismal movement (GO:0050879)3.58643539
63musculoskeletal movement (GO:0050881)3.58643539
64cilium movement (GO:0003341)3.45380658
65protein-DNA complex disassembly (GO:0032986)3.37722051
66nucleosome disassembly (GO:0006337)3.37722051
67microtubule nucleation (GO:0007020)3.36050964
68ether metabolic process (GO:0018904)3.35199100
69regulation of interleukin-13 production (GO:0032656)3.34233700
70peptidyl-threonine dephosphorylation (GO:0035970)3.22076546
71regulation of T-helper 2 cell differentiation (GO:0045628)3.21817217
72NAD biosynthetic process (GO:0009435)3.20625965
73cerebral cortex neuron differentiation (GO:0021895)3.19536447
74detection of chemical stimulus involved in sensory perception of smell (GO:0050911)3.17279882
75regulation of microtubule-based movement (GO:0060632)3.16460840
76organic cation transport (GO:0015695)3.14942617
77regulation of somitogenesis (GO:0014807)3.14663562
78mesenchymal cell differentiation involved in kidney development (GO:0072161)3.13320993
79mesenchymal cell differentiation involved in renal system development (GO:2001012)3.13320993
80cellular response to pH (GO:0071467)3.13148024
81regulation of histone H3-K27 methylation (GO:0061085)3.12187035
82cranial nerve morphogenesis (GO:0021602)3.05197932
83DNA conformation change (GO:0071103)3.03073634
84negative regulation of mesenchymal cell apoptotic process (GO:2001054)3.00610565
85polyamine biosynthetic process (GO:0006596)2.98741493
86negative regulation of histone methylation (GO:0031061)2.96249081
87cell recognition (GO:0008037)2.95893233
88glomerular visceral epithelial cell development (GO:0072015)2.94120046
89response to acidic pH (GO:0010447)2.92999598
90epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.92776444
91histone H3-K9 demethylation (GO:0033169)2.92337634
92Golgi to endosome transport (GO:0006895)2.87423757
93cell differentiation involved in metanephros development (GO:0072202)2.86935608
94multicellular organismal development (GO:0007275)2.86169887
95glomerular epithelial cell development (GO:0072310)2.85162958
96receptor recycling (GO:0001881)2.83753319
97acrosome reaction (GO:0007340)11.8026329
98sperm motility (GO:0030317)11.3849938
99fusion of sperm to egg plasma membrane (GO:0007342)10.6965543
100response to pheromone (GO:0019236)10.5540392

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.33518820
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.53949316
3MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human3.36942771
4POU5F1_26923725_Chip-Seq_MESODERM_Mouse2.63654938
5TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.63654938
6IRF4_20064451_ChIP-Seq_CD4+T_Mouse2.29925644
7CBP_20019798_ChIP-Seq_JUKART_Human2.29925644
8CTBP2_25329375_ChIP-Seq_LNCAP_Human2.28888024
9CTBP1_25329375_ChIP-Seq_LNCAP_Human2.13992185
10ERA_21632823_ChIP-Seq_H3396_Human2.12397792
11ELF1_20517297_ChIP-Seq_JURKAT_Human2.09661365
12VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human2.02520000
13EBNA2_21746931_ChIP-Seq_IB4-LCL_Human2.01827558
14EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.94770401
15DROSHA_22980978_ChIP-Seq_HELA_Human1.93669404
16WDR5_24793694_ChIP-Seq_LNCAP_Human1.90898069
17EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.89130521
18RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.88635008
19RAC3_21632823_ChIP-Seq_H3396_Human1.88334482
20UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.78980518
21ER_23166858_ChIP-Seq_MCF-7_Human1.77406005
22FUS_26573619_Chip-Seq_HEK293_Human1.77321508
23E2F1_20622854_ChIP-Seq_HELA_Human1.76339725
24EZH2_22144423_ChIP-Seq_EOC_Human1.76127182
25* NANOG_20526341_ChIP-Seq_ESCs_Human1.74639076
26CTCF_27219007_Chip-Seq_Bcells_Human1.70782726
27BCL6_27268052_Chip-Seq_Bcells_Human1.70317504
28MYC_19829295_ChIP-Seq_ESCs_Human1.68157607
29TAF2_19829295_ChIP-Seq_ESCs_Human1.64922459
30STAT6_21828071_ChIP-Seq_BEAS2B_Human1.64033416
31YY1_22570637_ChIP-Seq_MALME-3M_Human1.62596407
32ARNT_22903824_ChIP-Seq_MCF-7_Human1.60775075
33ZNF274_21170338_ChIP-Seq_K562_Hela1.60738160
34CTCF_20526341_ChIP-Seq_ESCs_Human1.58013133
35PHF8_20622854_ChIP-Seq_HELA_Human1.57373064
36ETV2_25802403_ChIP-Seq_MESCs_Mouse1.55980374
37BCOR_27268052_Chip-Seq_Bcells_Human1.54710020
38P68_20966046_ChIP-Seq_HELA_Human1.53836258
39SMC4_20622854_ChIP-Seq_HELA_Human1.53595918
40OCT4_20526341_ChIP-Seq_ESCs_Human1.52264519
41TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.51815871
42PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.50828092
43TDRD3_21172665_ChIP-Seq_MCF-7_Human1.50121023
44* AUTS2_25519132_ChIP-Seq_293T-REX_Human1.47158283
45P300_27268052_Chip-Seq_Bcells_Human1.45584336
46SMAD4_21741376_ChIP-Seq_EPCs_Human1.44317819
47TP63_22573176_ChIP-Seq_HFKS_Human1.43182800
48P300_19829295_ChIP-Seq_ESCs_Human1.42661796
49GATA3_21878914_ChIP-Seq_MCF-7_Human1.42120282
50SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.40484428
51SMAD3_21741376_ChIP-Seq_ESCs_Human1.38339846
52CEBPB_22108803_ChIP-Seq_LS180_Human1.37709132
53AR_25329375_ChIP-Seq_VCAP_Human1.36510200
54AR_21572438_ChIP-Seq_LNCaP_Human1.35350748
55P53_21459846_ChIP-Seq_SAOS-2_Human1.34443186
56MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.34220027
57TP63_19390658_ChIP-ChIP_HaCaT_Human1.33787507
58CBX2_22325352_ChIP-Seq_293T-Rex_Human1.32612554
59TP53_18474530_ChIP-ChIP_U2OS_Human1.32457760
60RBPJ_21746931_ChIP-Seq_IB4_Human1.30871605
61HNFA_21074721_ChIP-Seq_CACO-2_Human1.29315750
62SUZ12_27294783_Chip-Seq_ESCs_Mouse1.28041269
63ETV1_20927104_ChIP-Seq_GIST48_Human1.27920180
64SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.26707683
65CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.24456719
66ERG_20517297_ChIP-Seq_VCAP_Human1.24455538
67TAF15_26573619_Chip-Seq_HEK293_Human1.23857431
68P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.23658250
69NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.23651548
70KLF5_20875108_ChIP-Seq_MESCs_Mouse1.23636389
71EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.22669407
72KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.22627688
73SMAD3_21741376_ChIP-Seq_EPCs_Human1.21578202
74SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.20787025
75SMRT_27268052_Chip-Seq_Bcells_Human1.19073622
76TBL1_22424771_ChIP-Seq_293T_Human1.17555844
77TOP2B_26459242_ChIP-Seq_MCF-7_Human1.17382894
78SOX2_22085726_ChIP-Seq_NPCs_Mouse1.17287013
79NFYB_21822215_ChIP-Seq_K562_Human1.14820112
80PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.13155759
81GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12659448
82RUNX2_22187159_ChIP-Seq_PCA_Human1.11582089
83SA1_27219007_Chip-Seq_Bcells_Human1.10068656
84LXR_22292898_ChIP-Seq_THP-1_Human1.08929715
85GATA6_21074721_ChIP-Seq_CACO-2_Human1.08898726
86PHF8_20622853_ChIP-Seq_HELA_Human1.08772212
87SMAD4_21741376_ChIP-Seq_HESCs_Human1.07015411
88* HOXB7_26014856_ChIP-Seq_BT474_Human1.06061947
89ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.05622049
90RUNX1_26923725_Chip-Seq_HPCs_Mouse1.04805912
91FOXA1_25329375_ChIP-Seq_VCAP_Human1.04560892
92FOXA1_27270436_Chip-Seq_PROSTATE_Human1.04560892
93EZH2_27294783_Chip-Seq_ESCs_Mouse1.04401156
94* SOX2_19829295_ChIP-Seq_ESCs_Human1.03171751
95* NANOG_19829295_ChIP-Seq_ESCs_Human1.03171751
96TCF4_18268006_ChIP-ChIP_LS174T_Human1.02987590
97TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.02559921
98OCT1_27270436_Chip-Seq_PROSTATE_Human1.01170501
99RUNX_20019798_ChIP-Seq_JUKART_Human1.00633053
100PCGF4_22325352_ChIP-Seq_293T-Rex_Human0.99926179

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005377_hearing/vestibular/ear_phenot5.20759557
2MP0003878_abnormal_ear_physiology5.20759557
3MP0001348_abnormal_lacrimal_gland4.49381340
4MP0005670_abnormal_white_adipose4.47771227
5MP0003698_abnormal_male_reproductive4.24392966
6MP0001929_abnormal_gametogenesis3.67304080
7MP0000678_abnormal_parathyroid_gland2.75963598
8MP0005379_endocrine/exocrine_gland_phen2.41567903
9MP0002161_abnormal_fertility/fecundity2.33572687
10MP0002132_abnormal_respiratory_system2.14083464
11MP0003718_maternal_effect2.11894184
12MP0003646_muscle_fatigue2.09311531
13MP0005410_abnormal_fertilization11.9177361
14MP0003011_delayed_dark_adaptation1.90927414
15MP0002234_abnormal_pharynx_morphology1.87989281
16MP0002249_abnormal_larynx_morphology1.87771068
17MP0002282_abnormal_trachea_morphology1.84509645
18MP0009053_abnormal_anal_canal1.80185150
19MP0008877_abnormal_DNA_methylation1.78244157
20MP0002210_abnormal_sex_determination1.59895139
21MP0001485_abnormal_pinna_reflex1.47435216
22MP0004742_abnormal_vestibular_system1.44692636
23MP0001486_abnormal_startle_reflex1.42604702
24MP0002138_abnormal_hepatobiliary_system1.39691463
25MP0005423_abnormal_somatic_nervous1.34746183
26MP0005248_abnormal_Harderian_gland1.32264810
27MP0001145_abnormal_male_reproductive1.28313436
28MP0001968_abnormal_touch/_nociception1.27222893
29MP0002127_abnormal_cardiovascular_syste1.23103219
30MP0000653_abnormal_sex_gland1.20630944
31MP0004510_myositis1.15837413
32MP0000534_abnormal_ureter_morphology1.15760441
33MP0002822_catalepsy1.14516359
34MP0001765_abnormal_ion_homeostasis1.11293342
35MP0002735_abnormal_chemical_nociception1.09588704
36MP0000026_abnormal_inner_ear1.07883613
37MP0001963_abnormal_hearing_physiology1.03092507
38MP0000049_abnormal_middle_ear1.00376402
39MP0005310_abnormal_salivary_gland0.98409392
40MP0005367_renal/urinary_system_phenotyp0.90097863
41MP0000516_abnormal_urinary_system0.90097863
42MP0005395_other_phenotype0.90027342
43MP0000681_abnormal_thyroid_gland0.89053237
44MP0004859_abnormal_synaptic_plasticity0.88838456
45MP0003879_abnormal_hair_cell0.85988851
46MP0003119_abnormal_digestive_system0.84035299
47MP0006292_abnormal_olfactory_placode0.80569188
48MP0005551_abnormal_eye_electrophysiolog0.78872262
49MP0002653_abnormal_ependyma_morphology0.78653288
50MP0005451_abnormal_body_composition0.76780789
51MP0001666_abnormal_nutrient_absorption0.73995207
52MP0008961_abnormal_basal_metabolism0.71533045
53MP0002229_neurodegeneration0.70580679
54MP0004085_abnormal_heartbeat0.69703957
55MP0005167_abnormal_blood-brain_barrier0.69603836
56MP0002733_abnormal_thermal_nociception0.68038570
57MP0009115_abnormal_fat_cell0.67720309
58MP0000566_synostosis0.67544080
59MP0000955_abnormal_spinal_cord0.65688410
60MP0002067_abnormal_sensory_capabilities0.65242947
61MP0002557_abnormal_social/conspecific_i0.63967347
62MP0001879_abnormal_lymphatic_vessel0.62982186
63MP0001501_abnormal_sleep_pattern0.62314530
64MP0001984_abnormal_olfaction0.61986367
65MP0009697_abnormal_copulation0.60600171
66MP0002734_abnormal_mechanical_nocicepti0.60427707
67MP0000470_abnormal_stomach_morphology0.60127753
68MP0005666_abnormal_adipose_tissue0.59842924
69MP0009745_abnormal_behavioral_response0.57964047
70MP0002572_abnormal_emotion/affect_behav0.56836459
71MP0005623_abnormal_meninges_morphology0.56746771
72MP0005535_abnormal_body_temperature0.55927066
73MP0008569_lethality_at_weaning0.55343577
74MP0004233_abnormal_muscle_weight0.54996041
75MP0005636_abnormal_mineral_homeostasis0.54579872
76MP0005253_abnormal_eye_physiology0.53864254
77MP0005375_adipose_tissue_phenotype0.53785559
78MP0004036_abnormal_muscle_relaxation0.47936158
79MP0001970_abnormal_pain_threshold0.44168572
80MP0008995_early_reproductive_senescence0.43799730
81MP0001905_abnormal_dopamine_level0.43761064
82MP0004484_altered_response_of0.43159076
83MP0002272_abnormal_nervous_system0.42872181
84MP0000003_abnormal_adipose_tissue0.41972919
85MP0003077_abnormal_cell_cycle0.41565797
86MP0001440_abnormal_grooming_behavior0.40928638
87MP0005084_abnormal_gallbladder_morpholo0.40301626
88MP0001270_distended_abdomen0.39077154
89MP0005083_abnormal_biliary_tract0.37732736
90MP0003699_abnormal_female_reproductive0.36099397
91MP0003936_abnormal_reproductive_system0.35091021
92MP0000467_abnormal_esophagus_morphology0.34845233
93MP0000249_abnormal_blood_vessel0.34262050
94MP0003137_abnormal_impulse_conducting0.33851632
95MP0001293_anophthalmia0.33135143
96MP0003115_abnormal_respiratory_system0.32866120
97MP0008789_abnormal_olfactory_epithelium0.31606788
98MP0000230_abnormal_systemic_arterial0.30975148
99MP0002109_abnormal_limb_morphology0.30646506
100MP0000613_abnormal_salivary_gland0.30580355

Predicted human phenotypes

RankGene SetZ-score
1Severe visual impairment (HP:0001141)7.67241613
2Dynein arm defect of respiratory motile cilia (HP:0012255)6.44764549
3Absent/shortened dynein arms (HP:0200106)6.44764549
4Asymmetric septal hypertrophy (HP:0001670)5.15045856
5Attenuation of retinal blood vessels (HP:0007843)5.11847722
6Bony spicule pigmentary retinopathy (HP:0007737)5.01964628
7Abnormal ciliary motility (HP:0012262)4.89721651
8Abnormal respiratory motile cilium physiology (HP:0012261)4.62236655
9Abnormal respiratory motile cilium morphology (HP:0005938)4.55943046
10Abnormal respiratory epithelium morphology (HP:0012253)4.55943046
11Chronic hepatic failure (HP:0100626)4.52377174
12Nasal polyposis (HP:0100582)4.45144266
13Type II lissencephaly (HP:0007260)4.19912267
14Bell-shaped thorax (HP:0001591)4.09780975
15Resting tremor (HP:0002322)3.96140247
16Infertility (HP:0000789)3.93771642
17Potter facies (HP:0002009)3.93230251
18Facial shape deformation (HP:0011334)3.93230251
19Parkinsonism with favorable response to dopaminergic medication (HP:0002548)3.85260634
20Hypoplastic ischia (HP:0003175)3.79117787
21Male infertility (HP:0003251)3.71617566
22Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.70365099
23Abnormality of the nasal mucosa (HP:0000433)3.68582048
24Hyperkalemia (HP:0002153)3.65710975
25Abnormal rod and cone electroretinograms (HP:0008323)3.58653661
26Tubulointerstitial nephritis (HP:0001970)3.57522384
27Aplasia/Hypoplasia of the earlobes (HP:0009906)3.56203753
28Enlarged epiphyses (HP:0010580)3.53945907
29Abnormality of macular pigmentation (HP:0008002)3.47716122
30Retinal dysplasia (HP:0007973)3.43466076
31Azoospermia (HP:0000027)3.42773752
32Abnormal spermatogenesis (HP:0008669)3.36447769
33Impulsivity (HP:0100710)3.32377330
34Abnormality of the ischium (HP:0003174)3.30033477
35Cone-rod dystrophy (HP:0000548)3.23634722
36Aplasia/Hypoplasia of the pubic bone (HP:0009104)3.10651312
37Amelogenesis imperfecta (HP:0000705)3.00242112
38Unilateral renal agenesis (HP:0000122)2.90578171
39Nephronophthisis (HP:0000090)2.87239087
40Abnormality of dental color (HP:0011073)2.76112157
41Abnormal urine output (HP:0012590)2.75358113
42Abnormality of the aortic arch (HP:0012303)2.67523744
43Abnormal ventriculo-arterial connection (HP:0011563)2.67120171
44Transposition of the great arteries (HP:0001669)2.67120171
45Abnormal connection of the cardiac segments (HP:0011545)2.67120171
46Rhinitis (HP:0012384)2.66886370
47Congenital malformation of the right heart (HP:0011723)2.64168065
48Double outlet right ventricle (HP:0001719)2.64168065
49Muscle hypertrophy of the lower extremities (HP:0008968)2.62965010
50Postural instability (HP:0002172)2.61926949
51Hypoplasia of the thymus (HP:0000778)2.58957829
52Epiphyseal dysplasia (HP:0002656)2.58833679
53Stage 5 chronic kidney disease (HP:0003774)2.57843847
54Renal dysplasia (HP:0000110)2.55550347
55Progressive cerebellar ataxia (HP:0002073)2.52788683
56Calf muscle hypertrophy (HP:0008981)2.51240408
57Abnormality of renal excretion (HP:0011036)2.48672723
58Abnormality of the renal medulla (HP:0100957)2.37763337
59Sensory axonal neuropathy (HP:0003390)2.34443879
60Osteomalacia (HP:0002749)2.29369592
61Progressive sensorineural hearing impairment (HP:0000408)2.26727727
62Abnormal drinking behavior (HP:0030082)2.25757189
63Polydipsia (HP:0001959)2.25757189
64Generalized aminoaciduria (HP:0002909)2.23063244
65Polyuria (HP:0000103)2.21863031
66Abnormality of potassium homeostasis (HP:0011042)2.20388606
67Cerebellar dysplasia (HP:0007033)2.18876258
68Abnormality of the costochondral junction (HP:0000919)2.17362901
69Aplasia/Hypoplasia of the sacrum (HP:0008517)2.13071466
70Truncal obesity (HP:0001956)2.06504636
71Optic nerve hypoplasia (HP:0000609)2.06498208
72Spastic paraparesis (HP:0002313)2.03253344
73Absent epiphyses (HP:0010577)2.02979384
74Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.02979384
75Abnormality of the epiphysis of the femoral head (HP:0010574)2.01641678
76Bronchiectasis (HP:0002110)1.98452581
77Ventricular tachycardia (HP:0004756)1.97801656
78Abnormality of the pubic bones (HP:0003172)1.97487088
79Widely patent fontanelles and sutures (HP:0004492)1.97294772
80Portal hypertension (HP:0001409)1.95831695
81Intellectual disability, moderate (HP:0002342)1.92306163
82Flat capital femoral epiphysis (HP:0003370)1.92286128
83Abnormality of the parathyroid morphology (HP:0011766)1.90239977
84Tubulointerstitial abnormality (HP:0001969)1.89187290
85Hypoalphalipoproteinemia (HP:0003233)1.86598028
86Abnormality of femoral epiphyses (HP:0006499)1.86581057
87Abnormality involving the epiphyses of the lower limbs (HP:0006500)1.86581057
88Tetany (HP:0001281)1.86401716
89Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.80972794
90Flattened epiphyses (HP:0003071)1.80483737
91Recurrent corneal erosions (HP:0000495)1.79053131
92Hypoparathyroidism (HP:0000829)1.77138377
93Tubular atrophy (HP:0000092)1.77051726
94Hyponatremia (HP:0002902)1.76931798
95Abnormality of the femoral head (HP:0003368)1.76821099
96Decreased central vision (HP:0007663)1.76583595
97Abnormality of the hepatic vasculature (HP:0006707)1.76285280
98Short ribs (HP:0000773)1.75116507
99Hypophosphatemic rickets (HP:0004912)1.70389574
100Anterior segment dysgenesis (HP:0007700)1.69088159

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PLK48.79307428
2TESK15.64231621
3INSRR4.79236606
4DDR24.61855873
5MAP4K23.20066671
6PLK23.17803980
7BRD42.79181406
8PNCK2.64888853
9STK382.56152230
10CDK192.47199515
11MAPK152.05186116
12CAMK1G1.93103589
13WNK11.76923953
14MAP3K91.69064271
15STK38L1.65104297
16PRKD31.63606740
17PDPK11.59452053
18PIK3CG1.54268869
19PDK11.49844049
20MST1R1.40348656
21CDK71.35990255
22PTK2B1.27132342
23CDK121.26548056
24DYRK1B1.26208091
25LATS21.14552148
26KSR21.01476527
27NEK60.83283048
28TYRO30.81468344
29UHMK10.78927696
30PRKG10.77025146
31PRKAA20.75649112
32RPS6KA20.75544127
33SIK20.75409027
34CAMK1D0.69355325
35BMPR1B0.68937490
36PRKG20.67867457
37MAP3K110.65754660
38FRK0.63500153
39RPS6KA10.62175976
40ARAF0.60916628
41BRAF0.60016024
42LATS10.59335034
43MAP3K80.56718827
44MAP3K20.54010669
45PRKCZ0.49858015
46MARK10.49649315
47MUSK0.48754132
48MAP3K130.48669092
49CAMK10.47952583
50WNK40.47081559
51CDK30.46553446
52RPS6KA60.46115110
53GSK3B0.45953337
54CDK10.45722054
55CDK40.44676794
56CDK20.43598560
57ADRBK20.43509478
58MAPK10.43188863
59ROCK10.41691857
60RPS6KC10.41461759
61RPS6KL10.41461759
62MAP2K20.37942497
63TIE10.36972515
64MAPK110.36911724
65MAPK80.36161093
66AKT30.35577486
67STK390.33613419
68NTRK30.33161212
69PRKCG0.32799311
70MTOR0.32459875
71SGK2230.32043562
72SGK4940.32043562
73CHEK10.32029068
74CAMK40.30776211
75OBSCN0.28847007
76PRKCB0.28304667
77TLK10.28202944
78SGK10.27184861
79MAPK140.27105333
80IKBKB0.26495156
81PKN10.25208958
82OXSR10.24219812
83MAP3K40.20537688
84MAP3K10.20481524
85CHUK0.20267675
86DYRK30.19869866
87NTRK20.19238538
88MARK20.18823878
89AKT10.18620448
90MAPK100.16550150
91MET0.15421102
92PRKACA0.13919951
93PRKACB0.13702183
94PRKAA10.12019536
95RPS6KA30.10706297
96RIPK40.10666082
97TEC0.10327141
98BRSK10.10325387
99CDK11A0.10183638
100MAP3K70.08920495

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000727.34834227
2Fatty acid biosynthesis_Homo sapiens_hsa000614.61397511
3Olfactory transduction_Homo sapiens_hsa047404.51338551
4Butanoate metabolism_Homo sapiens_hsa006502.78281896
5Allograft rejection_Homo sapiens_hsa053302.64221903
6Autoimmune thyroid disease_Homo sapiens_hsa053202.62363177
7Graft-versus-host disease_Homo sapiens_hsa053322.48174346
8Type I diabetes mellitus_Homo sapiens_hsa049402.45642165
9Antigen processing and presentation_Homo sapiens_hsa046121.96427029
10Taste transduction_Homo sapiens_hsa047421.86748926
11Glycerophospholipid metabolism_Homo sapiens_hsa005641.86547993
12Dorso-ventral axis formation_Homo sapiens_hsa043201.76647486
13Viral myocarditis_Homo sapiens_hsa054161.73696160
14RNA transport_Homo sapiens_hsa030131.66509323
15Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.65555493
16Arginine and proline metabolism_Homo sapiens_hsa003301.52763824
17Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.50879233
18Type II diabetes mellitus_Homo sapiens_hsa049301.37578638
19Phototransduction_Homo sapiens_hsa047441.33972229
20Phenylalanine metabolism_Homo sapiens_hsa003601.29034780
21Maturity onset diabetes of the young_Homo sapiens_hsa049501.28111309
22Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.26812800
23Protein digestion and absorption_Homo sapiens_hsa049741.18289749
24Basal transcription factors_Homo sapiens_hsa030221.14338423
25Cardiac muscle contraction_Homo sapiens_hsa042601.09307737
26Endocytosis_Homo sapiens_hsa041441.02988593
27Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.02501987
28Fatty acid degradation_Homo sapiens_hsa000710.96829974
29Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.96173250
30Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.95955040
31Salivary secretion_Homo sapiens_hsa049700.95395272
32Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.92935338
33Calcium signaling pathway_Homo sapiens_hsa040200.92625683
34Oocyte meiosis_Homo sapiens_hsa041140.87274162
35Adipocytokine signaling pathway_Homo sapiens_hsa049200.86618502
36Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.86535073
37Arginine biosynthesis_Homo sapiens_hsa002200.86044407
38Glycerolipid metabolism_Homo sapiens_hsa005610.84447483
39cAMP signaling pathway_Homo sapiens_hsa040240.83774800
40Fat digestion and absorption_Homo sapiens_hsa049750.83401343
41Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.81952641
42ABC transporters_Homo sapiens_hsa020100.81060032
43Nicotine addiction_Homo sapiens_hsa050330.80279893
44Influenza A_Homo sapiens_hsa051640.79793212
45Selenocompound metabolism_Homo sapiens_hsa004500.75587689
46mRNA surveillance pathway_Homo sapiens_hsa030150.75268319
47Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.75114860
48Synaptic vesicle cycle_Homo sapiens_hsa047210.74273778
49Inositol phosphate metabolism_Homo sapiens_hsa005620.73146867
50Retinol metabolism_Homo sapiens_hsa008300.72340546
51Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.71893057
52Renin-angiotensin system_Homo sapiens_hsa046140.71666792
53Primary bile acid biosynthesis_Homo sapiens_hsa001200.71535179
54Thyroid hormone signaling pathway_Homo sapiens_hsa049190.70796462
55Hedgehog signaling pathway_Homo sapiens_hsa043400.70318596
56Nitrogen metabolism_Homo sapiens_hsa009100.69698517
57Morphine addiction_Homo sapiens_hsa050320.69281257
58Tyrosine metabolism_Homo sapiens_hsa003500.66073481
59Estrogen signaling pathway_Homo sapiens_hsa049150.61491808
60Fatty acid metabolism_Homo sapiens_hsa012120.61409791
61Fanconi anemia pathway_Homo sapiens_hsa034600.57983559
62MAPK signaling pathway_Homo sapiens_hsa040100.56712874
63Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.55490351
64Circadian entrainment_Homo sapiens_hsa047130.55379130
65Insulin secretion_Homo sapiens_hsa049110.54600266
66Purine metabolism_Homo sapiens_hsa002300.49877204
67Aldosterone synthesis and secretion_Homo sapiens_hsa049250.48414961
68Carbohydrate digestion and absorption_Homo sapiens_hsa049730.45937667
69Bile secretion_Homo sapiens_hsa049760.44791801
70PPAR signaling pathway_Homo sapiens_hsa033200.44423590
71Linoleic acid metabolism_Homo sapiens_hsa005910.43340892
72Phosphatidylinositol signaling system_Homo sapiens_hsa040700.42099577
73Glutamatergic synapse_Homo sapiens_hsa047240.41716135
74Vascular smooth muscle contraction_Homo sapiens_hsa042700.41467244
75Gastric acid secretion_Homo sapiens_hsa049710.40642571
76Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.38865430
77Steroid hormone biosynthesis_Homo sapiens_hsa001400.38853919
78Herpes simplex infection_Homo sapiens_hsa051680.38064671
79Viral carcinogenesis_Homo sapiens_hsa052030.36807959
80Renin secretion_Homo sapiens_hsa049240.35430094
81Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.34161110
82Tight junction_Homo sapiens_hsa045300.32780160
83cGMP-PKG signaling pathway_Homo sapiens_hsa040220.30334741
84Biosynthesis of amino acids_Homo sapiens_hsa012300.29637636
85Huntingtons disease_Homo sapiens_hsa050160.29523413
86Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.28385790
87Acute myeloid leukemia_Homo sapiens_hsa052210.27737608
88Intestinal immune network for IgA production_Homo sapiens_hsa046720.27483630
89Serotonergic synapse_Homo sapiens_hsa047260.25101137
90Epstein-Barr virus infection_Homo sapiens_hsa051690.25087757
91Tryptophan metabolism_Homo sapiens_hsa003800.24607421
92Jak-STAT signaling pathway_Homo sapiens_hsa046300.24290502
93Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.23446286
94Mineral absorption_Homo sapiens_hsa049780.22424611
95ECM-receptor interaction_Homo sapiens_hsa045120.21776714
96Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.21274425
97Chemical carcinogenesis_Homo sapiens_hsa052040.21019110
98Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.20907991
99Transcriptional misregulation in cancer_Homo sapiens_hsa052020.20025086
100Oxytocin signaling pathway_Homo sapiens_hsa049210.19654258

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »