GOLGA6L3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA packaging (GO:0006323)9.61786956
2sperm capacitation (GO:0048240)8.91588542
3plasma membrane fusion (GO:0045026)8.87852587
4microtubule depolymerization (GO:0007019)8.55814417
5spermatid nucleus differentiation (GO:0007289)8.31438175
6single strand break repair (GO:0000012)8.28612907
7sperm-egg recognition (GO:0035036)7.73442908
8spermatid development (GO:0007286)7.61082934
9binding of sperm to zona pellucida (GO:0007339)7.50004715
10sexual reproduction (GO:0019953)7.20382262
11antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G7.13634093
12negative regulation of inclusion body assembly (GO:0090084)7.01176992
13calcium ion-dependent exocytosis (GO:0017156)6.72413122
14multicellular organism reproduction (GO:0032504)6.66947497
15microtubule polymerization or depolymerization (GO:0031109)6.65337883
16rRNA methylation (GO:0031167)6.58971503
17reproduction (GO:0000003)6.57720699
18cell-cell recognition (GO:0009988)6.37560488
19cellular ketone body metabolic process (GO:0046950)6.26079037
20spermatogenesis (GO:0007283)5.89588544
21male gamete generation (GO:0048232)5.87480882
22protein polyglutamylation (GO:0018095)5.83790888
23axonemal dynein complex assembly (GO:0070286)5.77887879
24rRNA modification (GO:0000154)5.54845578
25ketone body metabolic process (GO:1902224)5.51862162
26protein targeting to Golgi (GO:0000042)5.47405917
27phosphatidylethanolamine biosynthetic process (GO:0006646)5.40526877
28gamete generation (GO:0007276)5.34922983
29establishment of protein localization to Golgi (GO:0072600)5.25414429
30microtubule severing (GO:0051013)5.24700980
31chromatin silencing (GO:0006342)5.21727880
32positive regulation of Rab GTPase activity (GO:0032851)5.10784274
33regulation of Rab GTPase activity (GO:0032313)5.10784274
34retrograde transport, vesicle recycling within Golgi (GO:0000301)5.07004772
35regulation of inclusion body assembly (GO:0090083)5.02137583
36phosphatidylethanolamine metabolic process (GO:0046337)4.95761651
37coenzyme catabolic process (GO:0009109)4.94128213
38negative regulation of Rho protein signal transduction (GO:0035024)4.80538471
39motile cilium assembly (GO:0044458)4.78024499
40single fertilization (GO:0007338)4.53247222
41centriole replication (GO:0007099)4.48695147
42cell wall macromolecule catabolic process (GO:0016998)4.41945212
43germ cell development (GO:0007281)4.31141836
44glycerol ether metabolic process (GO:0006662)4.29608416
45multicellular organismal reproductive process (GO:0048609)4.27822623
46regulation of somitogenesis (GO:0014807)4.21448794
47regulation of transcription involved in cell fate commitment (GO:0060850)4.20748949
48regulation of cilium movement (GO:0003352)4.16494492
49cellular process involved in reproduction in multicellular organism (GO:0022412)4.14023534
50centriole assembly (GO:0098534)3.99944910
51protein localization to Golgi apparatus (GO:0034067)3.98331746
52cell wall macromolecule metabolic process (GO:0044036)3.98272426
53ether metabolic process (GO:0018904)3.96171839
54mesenchymal cell differentiation involved in kidney development (GO:0072161)3.85257229
55mesenchymal cell differentiation involved in renal system development (GO:2001012)3.85257229
56RNA destabilization (GO:0050779)3.84031715
57nucleus organization (GO:0006997)3.83008774
58cilium or flagellum-dependent cell motility (GO:0001539)3.80670277
59cell differentiation involved in metanephros development (GO:0072202)3.71930387
60cartilage development involved in endochondral bone morphogenesis (GO:0060351)3.63897690
61negative regulation of gene expression, epigenetic (GO:0045814)3.61461202
62cranial nerve morphogenesis (GO:0021602)3.60470644
63fertilization (GO:0009566)3.59303491
64histone H3-K9 demethylation (GO:0033169)3.55287619
65regulation of centriole replication (GO:0046599)3.45851034
66NAD biosynthetic process (GO:0009435)3.40745993
67peptidyl-proline hydroxylation (GO:0019511)3.39999514
68tooth mineralization (GO:0034505)3.37346374
69epithelial cilium movement (GO:0003351)3.33146644
70nucleosome disassembly (GO:0006337)3.32736232
71protein-DNA complex disassembly (GO:0032986)3.32736232
72glomerular visceral epithelial cell development (GO:0072015)3.25097435
73seminiferous tubule development (GO:0072520)3.24619990
74regulation of interleukin-13 production (GO:0032656)3.24090002
75protein depolymerization (GO:0051261)3.23733630
76negative regulation of mesenchymal cell apoptotic process (GO:2001054)3.22318212
77response to acidic pH (GO:0010447)3.20522464
78regulation of T-helper 2 cell differentiation (GO:0045628)3.18944844
79glomerular epithelial cell development (GO:0072310)3.16976828
80DNA conformation change (GO:0071103)3.11320452
81organic cation transport (GO:0015695)3.10205127
82polyamine biosynthetic process (GO:0006596)3.10050538
83multicellular organismal movement (GO:0050879)3.09448328
84musculoskeletal movement (GO:0050881)3.09448328
85peptidyl-threonine dephosphorylation (GO:0035970)3.08627806
86cell recognition (GO:0008037)3.08152700
87metanephric mesenchyme development (GO:0072075)3.05841422
88opsonization (GO:0008228)3.05077338
89cerebral cortex neuron differentiation (GO:0021895)3.03778846
90regulation of microtubule-based movement (GO:0060632)3.03083699
91actin filament capping (GO:0051693)3.01134557
92cofactor catabolic process (GO:0051187)3.00189494
93cellular response to pH (GO:0071467)3.00132506
94pattern specification involved in kidney development (GO:0061004)3.00121745
95cilium movement (GO:0003341)2.99072276
96acrosome reaction (GO:0007340)12.6746773
97response to pheromone (GO:0019236)11.7099089
98fusion of sperm to egg plasma membrane (GO:0007342)11.6868548
99sperm motility (GO:0030317)10.8139242
100chromosome condensation (GO:0030261)10.2675225

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.96120906
2MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human4.08591635
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.60050594
4STAT6_21828071_ChIP-Seq_BEAS2B_Human2.80598650
5POU5F1_26923725_Chip-Seq_MESODERM_Mouse2.35669526
6TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.35669526
7ELF1_20517297_ChIP-Seq_JURKAT_Human2.33740050
8ERA_21632823_ChIP-Seq_H3396_Human2.17368094
9EBNA1_20929547_Chip-Seq_RAJI-cells_Human2.04843174
10CTBP2_25329375_ChIP-Seq_LNCAP_Human2.03631982
11IRF4_20064451_ChIP-Seq_CD4+T_Mouse2.01152475
12CBP_20019798_ChIP-Seq_JUKART_Human2.01152475
13VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.98851533
14RAC3_21632823_ChIP-Seq_H3396_Human1.95367067
15RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.93531963
16DROSHA_22980978_ChIP-Seq_HELA_Human1.92969571
17WDR5_24793694_ChIP-Seq_LNCAP_Human1.90542837
18E2F1_20622854_ChIP-Seq_HELA_Human1.89119749
19CTCF_27219007_Chip-Seq_Bcells_Human1.88915993
20NANOG_20526341_ChIP-Seq_ESCs_Human1.88888197
21EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.86651078
22BCL6_27268052_Chip-Seq_Bcells_Human1.78731399
23CTBP1_25329375_ChIP-Seq_LNCAP_Human1.76143562
24SMC4_20622854_ChIP-Seq_HELA_Human1.75083956
25TDRD3_21172665_ChIP-Seq_MCF-7_Human1.72985526
26YY1_22570637_ChIP-Seq_MALME-3M_Human1.71511372
27TAF2_19829295_ChIP-Seq_ESCs_Human1.68597518
28EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.67869714
29UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.67099499
30MYC_19829295_ChIP-Seq_ESCs_Human1.65224279
31P68_20966046_ChIP-Seq_HELA_Human1.65103250
32LXR_22292898_ChIP-Seq_THP-1_Human1.64497066
33PHF8_20622854_ChIP-Seq_HELA_Human1.63470430
34CTCF_20526341_ChIP-Seq_ESCs_Human1.63240535
35BCOR_27268052_Chip-Seq_Bcells_Human1.62920126
36MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.61739301
37TP63_22573176_ChIP-Seq_HFKS_Human1.60307884
38FUS_26573619_Chip-Seq_HEK293_Human1.53767803
39TP53_18474530_ChIP-ChIP_U2OS_Human1.52651242
40AUTS2_25519132_ChIP-Seq_293T-REX_Human1.52328808
41ARNT_22903824_ChIP-Seq_MCF-7_Human1.47864106
42SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.46575552
43ER_23166858_ChIP-Seq_MCF-7_Human1.46313031
44OCT4_20526341_ChIP-Seq_ESCs_Human1.45083373
45ETV2_25802403_ChIP-Seq_MESCs_Mouse1.43587440
46SUZ12_27294783_Chip-Seq_ESCs_Mouse1.42052600
47SMAD4_21741376_ChIP-Seq_EPCs_Human1.40277550
48PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.40010287
49SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.38514734
50RUNX_20019798_ChIP-Seq_JUKART_Human1.37012933
51P300_27268052_Chip-Seq_Bcells_Human1.36856234
52GATA3_21878914_ChIP-Seq_MCF-7_Human1.33766173
53THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.31889527
54HNFA_21074721_ChIP-Seq_CACO-2_Human1.31112526
55SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.29860926
56TP63_19390658_ChIP-ChIP_HaCaT_Human1.26908580
57P53_21459846_ChIP-Seq_SAOS-2_Human1.25911636
58EZH2_27294783_Chip-Seq_ESCs_Mouse1.25539415
59P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.25411307
60SA1_27219007_Chip-Seq_Bcells_Human1.25083585
61CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.24525276
62CBX2_22325352_ChIP-Seq_293T-Rex_Human1.23887170
63AR_25329375_ChIP-Seq_VCAP_Human1.23869515
64SOX2_22085726_ChIP-Seq_NPCs_Mouse1.23613939
65EZH2_22144423_ChIP-Seq_EOC_Human1.22870616
66SMAD3_21741376_ChIP-Seq_ESCs_Human1.21724734
67CEBPB_22108803_ChIP-Seq_LS180_Human1.20139381
68SMAD4_21741376_ChIP-Seq_HESCs_Human1.20073885
69RBPJ_21746931_ChIP-Seq_IB4_Human1.18536429
70NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.18516489
71KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.18107214
72TAF15_26573619_Chip-Seq_HEK293_Human1.17883622
73ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.13936195
74ETV1_20927104_ChIP-Seq_GIST48_Human1.12965084
75SMAD3_21741376_ChIP-Seq_EPCs_Human1.12746304
76PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.11449780
77SA1_27219007_Chip-Seq_ERYTHROID_Human1.10837165
78HOXB7_26014856_ChIP-Seq_BT474_Human1.09705319
79TOP2B_26459242_ChIP-Seq_MCF-7_Human1.08756491
80E2F1_17053090_ChIP-ChIP_MCF-7_Human1.08299322
81KLF5_20875108_ChIP-Seq_MESCs_Mouse1.08130029
82NFYB_21822215_ChIP-Seq_K562_Human1.07792604
83ERG_20517297_ChIP-Seq_VCAP_Human1.06864776
84SMRT_27268052_Chip-Seq_Bcells_Human1.06735209
85RUNX1_27514584_Chip-Seq_MCF-7_Human1.05647657
86TBL1_22424771_ChIP-Seq_293T_Human1.05091517
87P300_19829295_ChIP-Seq_ESCs_Human1.05075989
88CBX2_27304074_Chip-Seq_ESCs_Mouse1.04406717
89CSB_26484114_Chip-Seq_FIBROBLAST_Human1.04404831
90VDR_22108803_ChIP-Seq_LS180_Human1.01367671
91NFIB_24661679_ChIP-Seq_LUNG_Mouse1.01327405
92RUNX1_26923725_Chip-Seq_HPCs_Mouse1.00880200
93RUNX2_22187159_ChIP-Seq_PCA_Human0.98477572
94GATA6_21074721_ChIP-Seq_CACO-2_Human0.98199672
95PHF8_20622853_ChIP-Seq_HELA_Human0.97930401
96OCT1_27270436_Chip-Seq_PROSTATE_Human0.97571363
97ZNF274_21170338_ChIP-Seq_K562_Hela0.95581021
98STAT1_20625510_ChIP-Seq_HELA_Human0.95460029
99OCT4_19829295_ChIP-Seq_ESCs_Human0.95210057
100KLF5_25053715_ChIP-Seq_YYC3_Human0.94638655

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005377_hearing/vestibular/ear_phenot4.73706392
2MP0003878_abnormal_ear_physiology4.73706392
3MP0003698_abnormal_male_reproductive4.31462794
4MP0005670_abnormal_white_adipose4.16324540
5MP0001348_abnormal_lacrimal_gland3.73197740
6MP0001929_abnormal_gametogenesis3.60021493
7MP0000678_abnormal_parathyroid_gland3.25159225
8MP0003011_delayed_dark_adaptation3.08656277
9MP0002132_abnormal_respiratory_system2.47102505
10MP0002161_abnormal_fertility/fecundity2.40593334
11MP0003718_maternal_effect2.25604185
12MP0002234_abnormal_pharynx_morphology2.24231169
13MP0002249_abnormal_larynx_morphology2.08836523
14MP0004510_myositis2.05072724
15MP0005410_abnormal_fertilization12.3926724
16MP0003646_muscle_fatigue1.78740711
17MP0005423_abnormal_somatic_nervous1.74509780
18MP0005379_endocrine/exocrine_gland_phen1.64906853
19MP0009053_abnormal_anal_canal1.62878216
20MP0002282_abnormal_trachea_morphology1.53864689
21MP0001486_abnormal_startle_reflex1.41917897
22MP0002127_abnormal_cardiovascular_syste1.37766445
23MP0002210_abnormal_sex_determination1.36412063
24MP0004742_abnormal_vestibular_system1.36073823
25MP0001765_abnormal_ion_homeostasis1.32210370
26MP0000534_abnormal_ureter_morphology1.31675234
27MP0005310_abnormal_salivary_gland1.31457565
28MP0001485_abnormal_pinna_reflex1.22976117
29MP0005248_abnormal_Harderian_gland1.21586232
30MP0002735_abnormal_chemical_nociception1.21192274
31MP0001968_abnormal_touch/_nociception1.20528227
32MP0001145_abnormal_male_reproductive1.20212401
33MP0000681_abnormal_thyroid_gland1.18071621
34MP0000653_abnormal_sex_gland1.13667195
35MP0000049_abnormal_middle_ear1.12961997
36MP0000026_abnormal_inner_ear1.10209006
37MP0002138_abnormal_hepatobiliary_system1.08999204
38MP0001963_abnormal_hearing_physiology1.07948008
39MP0005395_other_phenotype1.07000027
40MP0004859_abnormal_synaptic_plasticity0.95612680
41MP0005367_renal/urinary_system_phenotyp0.91822106
42MP0000516_abnormal_urinary_system0.91822106
43MP0002733_abnormal_thermal_nociception0.90311498
44MP0002653_abnormal_ependyma_morphology0.90229887
45MP0001879_abnormal_lymphatic_vessel0.88592011
46MP0002229_neurodegeneration0.87335541
47MP0003879_abnormal_hair_cell0.85620674
48MP0006292_abnormal_olfactory_placode0.83430467
49MP0005083_abnormal_biliary_tract0.83364200
50MP0000566_synostosis0.79908191
51MP0000955_abnormal_spinal_cord0.79824282
52MP0005636_abnormal_mineral_homeostasis0.78666971
53MP0004085_abnormal_heartbeat0.76483043
54MP0008877_abnormal_DNA_methylation0.73940973
55MP0004484_altered_response_of0.71570920
56MP0005375_adipose_tissue_phenotype0.65775150
57MP0001666_abnormal_nutrient_absorption0.65662066
58MP0005666_abnormal_adipose_tissue0.64123387
59MP0002067_abnormal_sensory_capabilities0.63845757
60MP0005623_abnormal_meninges_morphology0.61895731
61MP0005167_abnormal_blood-brain_barrier0.61546054
62MP0005551_abnormal_eye_electrophysiolog0.60936409
63MP0000003_abnormal_adipose_tissue0.60522707
64MP0002822_catalepsy0.58324434
65MP0001970_abnormal_pain_threshold0.57954382
66MP0003119_abnormal_digestive_system0.57495614
67MP0008569_lethality_at_weaning0.55297254
68MP0000249_abnormal_blood_vessel0.55290981
69MP0002557_abnormal_social/conspecific_i0.55279768
70MP0003172_abnormal_lysosome_physiology0.53622628
71MP0008995_early_reproductive_senescence0.53081834
72MP0003942_abnormal_urinary_system0.51550720
73MP0000613_abnormal_salivary_gland0.51199902
74MP0008961_abnormal_basal_metabolism0.50929164
75MP0009115_abnormal_fat_cell0.49282746
76MP0003137_abnormal_impulse_conducting0.47715011
77MP0002572_abnormal_emotion/affect_behav0.46260448
78MP0001501_abnormal_sleep_pattern0.46145927
79MP0004233_abnormal_muscle_weight0.45173253
80MP0002734_abnormal_mechanical_nocicepti0.44951125
81MP0008789_abnormal_olfactory_epithelium0.44565314
82MP0003880_abnormal_central_pattern0.43544298
83MP0002272_abnormal_nervous_system0.42974369
84MP0000470_abnormal_stomach_morphology0.42540953
85MP0003936_abnormal_reproductive_system0.41342514
86MP0005253_abnormal_eye_physiology0.39581683
87MP0000467_abnormal_esophagus_morphology0.39519174
88MP0003699_abnormal_female_reproductive0.38665326
89MP0000163_abnormal_cartilage_morphology0.37974845
90MP0001984_abnormal_olfaction0.36433244
91MP0005647_abnormal_sex_gland0.36424287
92MP0002928_abnormal_bile_duct0.36403089
93MP0001440_abnormal_grooming_behavior0.34886092
94MP0005408_hypopigmentation0.34837517
95MP0005535_abnormal_body_temperature0.34433175
96MP0002115_abnormal_skeleton_extremities0.34303216
97MP0000230_abnormal_systemic_arterial0.34137874
98MP0004036_abnormal_muscle_relaxation0.34118578
99MP0003091_abnormal_cell_migration0.33161035
100MP0005166_decreased_susceptibility_to0.32948444

Predicted human phenotypes

RankGene SetZ-score
1Severe visual impairment (HP:0001141)9.19548229
2Dynein arm defect of respiratory motile cilia (HP:0012255)5.47824434
3Absent/shortened dynein arms (HP:0200106)5.47824434
4Attenuation of retinal blood vessels (HP:0007843)5.35293415
5Bony spicule pigmentary retinopathy (HP:0007737)5.27398976
6Asymmetric septal hypertrophy (HP:0001670)5.02187683
7Hypoplastic ischia (HP:0003175)4.80407249
8Abnormal rod and cone electroretinograms (HP:0008323)4.78218303
9Bell-shaped thorax (HP:0001591)4.70407021
10Enlarged epiphyses (HP:0010580)4.62515578
11Resting tremor (HP:0002322)4.48736342
12Abnormal ciliary motility (HP:0012262)4.28607347
13Abnormality of the ischium (HP:0003174)4.21170171
14Parkinsonism with favorable response to dopaminergic medication (HP:0002548)4.15128068
15Azoospermia (HP:0000027)4.14819516
16Abnormal respiratory motile cilium physiology (HP:0012261)4.10664181
17Aplasia/Hypoplasia of the pubic bone (HP:0009104)4.02246224
18Abnormal respiratory epithelium morphology (HP:0012253)4.00429652
19Abnormal respiratory motile cilium morphology (HP:0005938)4.00429652
20Facial shape deformation (HP:0011334)3.97095107
21Potter facies (HP:0002009)3.97095107
22Unilateral renal agenesis (HP:0000122)3.96881659
23Nasal polyposis (HP:0100582)3.91960833
24Infertility (HP:0000789)3.90167615
25Hyperkalemia (HP:0002153)3.88876239
26Male infertility (HP:0003251)3.61156929
27Abnormality of macular pigmentation (HP:0008002)3.58294908
28Abnormal spermatogenesis (HP:0008669)3.58078258
29Aplasia/Hypoplasia of the earlobes (HP:0009906)3.54933459
30Double outlet right ventricle (HP:0001719)3.54045105
31Congenital malformation of the right heart (HP:0011723)3.54045105
32Abnormality of the aortic arch (HP:0012303)3.46300002
33Tubulointerstitial nephritis (HP:0001970)3.24468553
34Abnormality of the nasal mucosa (HP:0000433)3.19395103
35Renal dysplasia (HP:0000110)3.14099333
36Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.05322476
37Impulsivity (HP:0100710)2.89064254
38Abnormality of the parathyroid morphology (HP:0011766)2.81856593
39Flattened epiphyses (HP:0003071)2.78159483
40Cone-rod dystrophy (HP:0000548)2.77072828
41Absent epiphyses (HP:0010577)2.76274421
42Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.76274421
43Chronic hepatic failure (HP:0100626)2.75956688
44Generalized aminoaciduria (HP:0002909)2.70998484
45Hypoplasia of the thymus (HP:0000778)2.68386641
46Abnormal urine output (HP:0012590)2.64242370
47Epiphyseal dysplasia (HP:0002656)2.63434863
48Hyperthyroidism (HP:0000836)2.57175796
49Postural instability (HP:0002172)2.55212482
50Stage 5 chronic kidney disease (HP:0003774)2.53442756
51Abnormality of the costochondral junction (HP:0000919)2.50892043
52Abnormality of the epiphysis of the femoral head (HP:0010574)2.43437753
53Tetany (HP:0001281)2.41859023
54Abnormality of the pubic bones (HP:0003172)2.40886319
55Ventricular tachycardia (HP:0004756)2.40547104
56Abnormality of potassium homeostasis (HP:0011042)2.39304532
57Progressive sensorineural hearing impairment (HP:0000408)2.36989727
58Abnormality of femoral epiphyses (HP:0006499)2.29103708
59Abnormality involving the epiphyses of the lower limbs (HP:0006500)2.29103708
60Aplasia/Hypoplasia of the sacrum (HP:0008517)2.28891492
61Rhinitis (HP:0012384)2.23868856
62Abnormality of renal excretion (HP:0011036)2.23374627
63Hyponatremia (HP:0002902)2.18627212
64Atelectasis (HP:0100750)2.18409401
65Flat capital femoral epiphysis (HP:0003370)2.18166495
66Abnormality of the femoral head (HP:0003368)2.17847950
67Nephronophthisis (HP:0000090)2.16362490
68Focal segmental glomerulosclerosis (HP:0000097)2.15217140
69Abnormal ventriculo-arterial connection (HP:0011563)2.14035330
70Transposition of the great arteries (HP:0001669)2.14035330
71Abnormal connection of the cardiac segments (HP:0011545)2.14035330
72Hypoparathyroidism (HP:0000829)2.13534743
73Hypophosphatemic rickets (HP:0004912)2.12493422
74Decreased central vision (HP:0007663)2.11430932
75Widely patent fontanelles and sutures (HP:0004492)2.09233475
76Polyuria (HP:0000103)2.06328040
77Bowel incontinence (HP:0002607)2.06279996
78Osteomalacia (HP:0002749)2.05130127
79Amelogenesis imperfecta (HP:0000705)2.04781836
80Amblyopia (HP:0000646)2.04523246
81Polydipsia (HP:0001959)2.03543793
82Abnormal drinking behavior (HP:0030082)2.03543793
83Vertebral clefting (HP:0008428)2.03337768
84Mixed hearing impairment (HP:0000410)2.02816866
85Sensory axonal neuropathy (HP:0003390)2.02237211
86Progressive cerebellar ataxia (HP:0002073)1.98625270
87Spastic paraparesis (HP:0002313)1.97160474
88Bradycardia (HP:0001662)1.96830030
89Abnormality of dental color (HP:0011073)1.95397947
90Truncal obesity (HP:0001956)1.92492394
91Abnormal large intestine physiology (HP:0012700)1.91858419
92Pendular nystagmus (HP:0012043)1.89792346
93Short ribs (HP:0000773)1.87064452
94Hypoplastic left heart (HP:0004383)1.86559976
95Muscle fiber atrophy (HP:0100295)1.86075500
96Bulbous nose (HP:0000414)1.85850000
97Protuberant abdomen (HP:0001538)1.85809563
98Neoplasm of the heart (HP:0100544)1.82905352
99Abnormality of the renal medulla (HP:0100957)1.81867302
100Fatigable weakness (HP:0003473)1.81055825

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PLK47.38998728
2TESK16.82968790
3DDR26.05328252
4MAP4K24.93521688
5INSRR4.36332580
6PLK22.77519892
7BRD42.62694074
8STK382.54237231
9MAPK152.50818086
10WNK12.45400041
11MST1R2.02698000
12PNCK1.96407718
13CAMK1G1.84459944
14PRKD31.83505765
15STK38L1.64250663
16PDPK11.52352066
17CDK71.45653078
18CDK121.43032639
19PDK11.40856926
20PIK3CG1.38400616
21DYRK1B1.24949739
22WNK41.22981562
23KSR21.22722274
24MAP3K91.22434863
25PTK2B1.05519925
26LATS20.90800794
27UHMK10.88984414
28CAMK1D0.86727834
29PRKAA20.84855812
30NEK60.81622629
31RPS6KA20.78971881
32MUSK0.74062769
33MAP2K20.67734809
34MAP3K80.66550678
35BRAF0.65853394
36CDK40.65642418
37MAP3K110.65471494
38MAP3K20.65264378
39PRKG20.64233132
40RPS6KA10.62451406
41ROCK10.61835529
42MARK20.61133074
43CAMK10.58894405
44PRKG10.58595333
45CAMK40.47975172
46CDK30.47558029
47STK390.46963280
48AKT30.46330769
49ARAF0.46177728
50RPS6KC10.45257564
51RPS6KL10.45257564
52GSK3B0.43386968
53RPS6KA60.41904482
54MTOR0.40568568
55MAPK10.40432642
56CDK10.38716058
57CDK20.38615806
58PRKCZ0.37803055
59MET0.37428832
60SIK20.36836223
61MARK10.34429433
62LATS10.34069729
63BMPR1B0.33462693
64MAPK80.33144441
65PRKCG0.32759779
66CHEK10.28218969
67TIE10.27877854
68MAP3K10.27355380
69MAP3K70.26805734
70SGK2230.24795130
71SGK4940.24795130
72SGK10.21911495
73MAPK140.21089356
74AKT10.20675863
75MAPK100.20379057
76NTRK30.19945751
77BLK0.17538639
78MAPK110.17511294
79FRK0.16565649
80PRKCB0.16308477
81TYRO30.15670360
82ABL20.15451651
83PKN10.15361659
84IKBKB0.13452431
85PINK10.12910958
86FER0.12834814
87BRSK10.11512856
88MAP3K130.11210725
89MAPK90.10890427
90DYRK30.10788823
91PRKAA10.09833591
92MOS0.09228652
93ROCK20.08839398
94PRKACA0.07659828
95CHUK0.06004921
96DYRK20.05524965
97RPS6KA30.05229337
98CAMK2A0.05130470
99TESK20.05015212
100LMTK20.04544082

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000728.86786287
2Fatty acid biosynthesis_Homo sapiens_hsa000614.57950180
3Olfactory transduction_Homo sapiens_hsa047403.61338607
4Butanoate metabolism_Homo sapiens_hsa006502.93313914
5Allograft rejection_Homo sapiens_hsa053302.62671013
6Autoimmune thyroid disease_Homo sapiens_hsa053202.52630445
7Graft-versus-host disease_Homo sapiens_hsa053322.41939017
8Type I diabetes mellitus_Homo sapiens_hsa049402.40809406
9Antigen processing and presentation_Homo sapiens_hsa046122.09005439
10Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.82870406
11Taste transduction_Homo sapiens_hsa047421.81722429
12Viral myocarditis_Homo sapiens_hsa054161.81169737
13Phenylalanine metabolism_Homo sapiens_hsa003601.80321972
14Arginine and proline metabolism_Homo sapiens_hsa003301.78387137
15Glycerophospholipid metabolism_Homo sapiens_hsa005641.74086466
16Dorso-ventral axis formation_Homo sapiens_hsa043201.70759685
17Type II diabetes mellitus_Homo sapiens_hsa049301.60678264
18Fatty acid degradation_Homo sapiens_hsa000711.25142137
19Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.24148001
20Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.23489585
21Endocytosis_Homo sapiens_hsa041441.22012869
22Salivary secretion_Homo sapiens_hsa049701.18535592
23Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.17207014
24Protein digestion and absorption_Homo sapiens_hsa049741.14116061
25Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.09656821
26RNA transport_Homo sapiens_hsa030131.08878072
27Fatty acid metabolism_Homo sapiens_hsa012121.04089834
28Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.03788690
29Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.02349581
30Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.99331094
31Arginine biosynthesis_Homo sapiens_hsa002200.97366379
32Oocyte meiosis_Homo sapiens_hsa041140.89207389
33Influenza A_Homo sapiens_hsa051640.89140001
34Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.84761348
35Cardiac muscle contraction_Homo sapiens_hsa042600.83715430
36Phototransduction_Homo sapiens_hsa047440.82838318
37Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.81854613
38Adipocytokine signaling pathway_Homo sapiens_hsa049200.80452307
39cAMP signaling pathway_Homo sapiens_hsa040240.80384312
40Fat digestion and absorption_Homo sapiens_hsa049750.79363297
41Tyrosine metabolism_Homo sapiens_hsa003500.79086848
42Aldosterone synthesis and secretion_Homo sapiens_hsa049250.73033740
43Retinol metabolism_Homo sapiens_hsa008300.70384298
44Thyroid hormone signaling pathway_Homo sapiens_hsa049190.68457791
45PPAR signaling pathway_Homo sapiens_hsa033200.67670868
46Estrogen signaling pathway_Homo sapiens_hsa049150.67370343
47Calcium signaling pathway_Homo sapiens_hsa040200.67067873
48Inositol phosphate metabolism_Homo sapiens_hsa005620.67054464
49Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.66563518
50Renin-angiotensin system_Homo sapiens_hsa046140.66181774
51Morphine addiction_Homo sapiens_hsa050320.60836530
52Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.59765554
53Hedgehog signaling pathway_Homo sapiens_hsa043400.54655714
54ABC transporters_Homo sapiens_hsa020100.54117753
55Insulin secretion_Homo sapiens_hsa049110.53031534
56Glycerolipid metabolism_Homo sapiens_hsa005610.52389904
57Circadian entrainment_Homo sapiens_hsa047130.51464285
58Acute myeloid leukemia_Homo sapiens_hsa052210.48704609
59MAPK signaling pathway_Homo sapiens_hsa040100.47142573
60Bile secretion_Homo sapiens_hsa049760.46773008
61Phosphatidylinositol signaling system_Homo sapiens_hsa040700.45394980
62Vascular smooth muscle contraction_Homo sapiens_hsa042700.44939344
63Purine metabolism_Homo sapiens_hsa002300.44896931
64VEGF signaling pathway_Homo sapiens_hsa043700.44003497
65Viral carcinogenesis_Homo sapiens_hsa052030.41558605
66Carbohydrate digestion and absorption_Homo sapiens_hsa049730.40028811
67Glutamatergic synapse_Homo sapiens_hsa047240.39996620
68Maturity onset diabetes of the young_Homo sapiens_hsa049500.38243618
69mRNA surveillance pathway_Homo sapiens_hsa030150.36933528
70Primary bile acid biosynthesis_Homo sapiens_hsa001200.36818020
71Gastric acid secretion_Homo sapiens_hsa049710.36492570
72Renin secretion_Homo sapiens_hsa049240.36294671
73Tight junction_Homo sapiens_hsa045300.35547518
74Nicotine addiction_Homo sapiens_hsa050330.34942751
75Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.33120651
76ECM-receptor interaction_Homo sapiens_hsa045120.32796606
77Herpes simplex infection_Homo sapiens_hsa051680.31724874
78Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.30556507
79Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.30274927
80Epstein-Barr virus infection_Homo sapiens_hsa051690.28187338
81Basal transcription factors_Homo sapiens_hsa030220.27776494
82Jak-STAT signaling pathway_Homo sapiens_hsa046300.27324464
83Cholinergic synapse_Homo sapiens_hsa047250.26424984
84Notch signaling pathway_Homo sapiens_hsa043300.25377481
85Pancreatic secretion_Homo sapiens_hsa049720.24938695
86Synaptic vesicle cycle_Homo sapiens_hsa047210.24776718
87Adherens junction_Homo sapiens_hsa045200.19844875
88Serotonergic synapse_Homo sapiens_hsa047260.18601239
89Legionellosis_Homo sapiens_hsa051340.18306989
90cGMP-PKG signaling pathway_Homo sapiens_hsa040220.18264183
91Steroid hormone biosynthesis_Homo sapiens_hsa001400.17828228
92Thyroid hormone synthesis_Homo sapiens_hsa049180.14506591
93Toxoplasmosis_Homo sapiens_hsa051450.14498733
94Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.14434968
95Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.14367474
96Oxytocin signaling pathway_Homo sapiens_hsa049210.14237928
97Nitrogen metabolism_Homo sapiens_hsa009100.12981912
98beta-Alanine metabolism_Homo sapiens_hsa004100.12818946
99Prolactin signaling pathway_Homo sapiens_hsa049170.12641082
100Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.11755671

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »