ARCHS4

Functional Annotation Prediction

Predicted biological processes (GO)

Rank	Gene Set	Z-score
1	L-phenylalanine catabolic process (GO:0006559)	7.17249753
2	erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)	7.17249753
3	L-phenylalanine metabolic process (GO:0006558)	6.93852766
4	erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)	6.93852766
5	triglyceride-rich lipoprotein particle remodeling (GO:0034370)	6.58909874
6	epoxygenase P450 pathway (GO:0019373)	6.37155346
7	aromatic amino acid family catabolic process (GO:0009074)	6.22711527
8	high-density lipoprotein particle remodeling (GO:0034375)	5.60491547
9	tryptophan catabolic process (GO:0006569)	5.39320229
10	indole-containing compound catabolic process (GO:0042436)	5.39320229
11	indolalkylamine catabolic process (GO:0046218)	5.39320229
12	urea cycle (GO:0000050)	5.38267587
13	urea metabolic process (GO:0019627)	5.38267587
14	kynurenine metabolic process (GO:0070189)	5.25958343
15	glyoxylate metabolic process (GO:0046487)	5.25669255
16	regulation of cholesterol esterification (GO:0010872)	5.24872131
17	regulation of triglyceride catabolic process (GO:0010896)	5.15950331
18	tryptophan metabolic process (GO:0006568)	5.15636818
19	bile acid biosynthetic process (GO:0006699)	5.15205299
20	cysteine metabolic process (GO:0006534)	5.14823011
21	phenylpropanoid metabolic process (GO:0009698)	5.09390862
22	sulfur amino acid catabolic process (GO:0000098)	5.07454428
23	reverse cholesterol transport (GO:0043691)	5.06636509
24	alpha-linolenic acid metabolic process (GO:0036109)	5.06023885
25	omega-hydroxylase P450 pathway (GO:0097267)	5.05201672
26	phospholipid efflux (GO:0033700)	5.01669323
27	nitrogen cycle metabolic process (GO:0071941)	4.95813780
28	intestinal cholesterol absorption (GO:0030299)	4.90582515
29	negative regulation of fibrinolysis (GO:0051918)	4.82707302
30	peptidyl-glutamic acid carboxylation (GO:0017187)	4.81129307
31	protein carboxylation (GO:0018214)	4.81129307
32	plasma lipoprotein particle remodeling (GO:0034369)	4.79438968
33	protein-lipid complex remodeling (GO:0034368)	4.79438968
34	macromolecular complex remodeling (GO:0034367)	4.79438968
35	homocysteine metabolic process (GO:0050667)	4.74602930
36	negative regulation of sterol transport (GO:0032372)	4.72752818
37	negative regulation of cholesterol transport (GO:0032375)	4.72752818
38	acylglycerol homeostasis (GO:0055090)	4.66189527
39	triglyceride homeostasis (GO:0070328)	4.66189527
40	serine family amino acid catabolic process (GO:0009071)	4.66151305
41	regulation of fibrinolysis (GO:0051917)	4.63306785
42	bile acid metabolic process (GO:0008206)	4.63260177
43	blood coagulation, intrinsic pathway (GO:0007597)	4.60303195
44	aromatic amino acid family metabolic process (GO:0009072)	4.59189980
45	fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)	4.52605243
46	cholesterol efflux (GO:0033344)	4.50536481
47	tyrosine metabolic process (GO:0006570)	4.47074474
48	complement activation, alternative pathway (GO:0006957)	4.44189547
49	drug catabolic process (GO:0042737)	4.43087075
50	regulation of protein activation cascade (GO:2000257)	4.40777144
51	lysine metabolic process (GO:0006553)	4.40775297
52	lysine catabolic process (GO:0006554)	4.40775297
53	plasma lipoprotein particle assembly (GO:0034377)	4.39132969
54	ethanol oxidation (GO:0006069)	4.33644053
55	bile acid and bile salt transport (GO:0015721)	4.33310968
56	positive regulation of lipoprotein lipase activity (GO:0051006)	4.33240532
57	positive regulation of triglyceride lipase activity (GO:0061365)	4.33240532
58	amino-acid betaine metabolic process (GO:0006577)	4.30948082
59	cellular ketone body metabolic process (GO:0046950)	4.28015842
60	alpha-amino acid catabolic process (GO:1901606)	4.21122950
61	intestinal absorption (GO:0050892)	4.20517580
62	regulation of bile acid biosynthetic process (GO:0070857)	4.17900777
63	negative regulation of protein activation cascade (GO:2000258)	4.16884791
64	plasma lipoprotein particle clearance (GO:0034381)	4.14193678
65	regulation of complement activation (GO:0030449)	4.08429115
66	regulation of plasminogen activation (GO:0010755)	4.05963352
67	fructose metabolic process (GO:0006000)	3.97951745
68	very-low-density lipoprotein particle assembly (GO:0034379)	3.96651811
69	flavonoid metabolic process (GO:0009812)	3.95738149
70	regulation of cholesterol homeostasis (GO:2000188)	3.94083147
71	protein-lipid complex assembly (GO:0065005)	3.93854153
72	oxidative demethylation (GO:0070989)	3.93843753
73	acute-phase response (GO:0006953)	3.93830694
74	lipoprotein metabolic process (GO:0042157)	3.93757970
75	cellular amino acid catabolic process (GO:0009063)	3.93619771
76	cellular modified amino acid catabolic process (GO:0042219)	3.92584630
77	indolalkylamine metabolic process (GO:0006586)	3.91849315
78	glutamate metabolic process (GO:0006536)	3.90257542
79	heme transport (GO:0015886)	3.90157852
80	cholesterol homeostasis (GO:0042632)	3.89725144
81	coenzyme catabolic process (GO:0009109)	3.87257488
82	cellular glucuronidation (GO:0052695)	3.86524414
83	negative regulation of hemostasis (GO:1900047)	3.86258430
84	negative regulation of blood coagulation (GO:0030195)	3.86258430
85	sterol homeostasis (GO:0055092)	3.84102983
86	glycine metabolic process (GO:0006544)	3.79570879
87	arginine metabolic process (GO:0006525)	3.78951007
88	plasma lipoprotein particle organization (GO:0071827)	3.76492895
89	regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)	3.76115903
90	serine family amino acid metabolic process (GO:0009069)	3.76071264
91	benzene-containing compound metabolic process (GO:0042537)	3.72788537
92	cellular biogenic amine catabolic process (GO:0042402)	3.71600710
93	amine catabolic process (GO:0009310)	3.71600710
94	positive regulation of lipid catabolic process (GO:0050996)	3.69641920
95	ketone body metabolic process (GO:1902224)	3.68817354
96	drug transmembrane transport (GO:0006855)	3.67607686
97	phospholipid homeostasis (GO:0055091)	3.66545450
98	imidazole-containing compound metabolic process (GO:0052803)	3.64271887
99	doxorubicin metabolic process (GO:0044598)	3.61962988
100	daunorubicin metabolic process (GO:0044597)	3.61962988
101	polyketide metabolic process (GO:0030638)	3.61962988
102	negative regulation of complement activation (GO:0045916)	3.61686162
103	negative regulation of coagulation (GO:0050819)	3.61146846
104	ethanol metabolic process (GO:0006067)	3.61091175
105	drug metabolic process (GO:0017144)	3.60206614
106	protein activation cascade (GO:0072376)	3.59078104
107	xenobiotic catabolic process (GO:0042178)	3.58123240
108	negative regulation of wound healing (GO:0061045)	3.56034920
109	negative regulation of lipase activity (GO:0060192)	3.54338065
110	protein-lipid complex subunit organization (GO:0071825)	3.54243264
111	exogenous drug catabolic process (GO:0042738)	3.53233630
112	carboxylic acid catabolic process (GO:0046395)	3.51965416
113	organic acid catabolic process (GO:0016054)	3.51965416
114	serine family amino acid biosynthetic process (GO:0009070)	3.51884962
115	low-density lipoprotein particle remodeling (GO:0034374)	3.50479489
116	aldehyde catabolic process (GO:0046185)	3.49559583
117	glucuronate metabolic process (GO:0019585)	3.45963066
118	uronic acid metabolic process (GO:0006063)	3.45963066
119	positive regulation of fatty acid biosynthetic process (GO:0045723)	3.45473023
120	dicarboxylic acid biosynthetic process (GO:0043650)	3.45271120
121	short-chain fatty acid metabolic process (GO:0046459)	3.43846530
122	fibrinolysis (GO:0042730)	3.42050381
123	alkaloid metabolic process (GO:0009820)	3.41317911
124	complement activation, classical pathway (GO:0006958)	3.39053247
125	proline metabolic process (GO:0006560)	3.38641633
126	hormone catabolic process (GO:0042447)	3.37634667
127	urate metabolic process (GO:0046415)	3.36205867
128	fat-soluble vitamin biosynthetic process (GO:0042362)	3.28987214
129	L-ascorbic acid metabolic process (GO:0019852)	3.26132900
130	regulation of humoral immune response (GO:0002920)	3.25628273
131	complement activation (GO:0006956)	3.23397467
132	NADH metabolic process (GO:0006734)	3.19242889

Predicted upstream transcription factors (ChEA)

Rank	Gene Set	Z-score
1	RXR_22158963_ChIP-Seq_LIVER_Mouse	8.03887962
2	* PPARA_22158963_ChIP-Seq_LIVER_Mouse	6.98077938
3	EGR1_23403033_ChIP-Seq_LIVER_Mouse	6.47483214
4	LXR_22158963_ChIP-Seq_LIVER_Mouse	6.29613121
5	CEBPA_23403033_ChIP-Seq_LIVER_Mouse	4.96927658
6	FOXO1_23066095_ChIP-Seq_LIVER_Mouse	4.91859834
7	PPARG_19300518_ChIP-PET_3T3-L1_Mouse	4.55373123
8	NR1I2_20693526_ChIP-Seq_LIVER_Mouse	3.83187322
9	CEBPB_23403033_ChIP-Seq_LIVER_Mouse	3.77995472
10	E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse	2.53902194
11	* HNF4A_19761587_ChIP-ChIP_CACO-2_Human	2.51662290
12	GATA1_22025678_ChIP-Seq_K562_Human	2.04874745
13	ESR1_17901129_ChIP-ChIP_LIVER_Mouse	11.2574747
14	* TCF7L2_21901280_ChIP-Seq_H4IIE_Rat	1.94106194
15	TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse	1.93638911
16	SOX2_27498859_Chip-Seq_STOMACH_Mouse	1.72893617
17	NR4A2_19515692_ChIP-ChIP_MN9D_Mouse	1.69185975
18	CLOCK_20551151_ChIP-Seq_293T_Human	1.66965166
19	* FOXA2_19822575_ChIP-Seq_HepG2_Human	1.64685028
20	STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse	1.57712828
21	HNF4A_19822575_ChIP-Seq_HepG2_Human	1.55790861
22	GATA4_25053715_ChIP-Seq_YYC3_Human	1.44127082
23	ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse	1.39811722
24	ESR1_20079471_ChIP-ChIP_T-47D_Human	1.33281701
25	HTT_18923047_ChIP-ChIP_STHdh_Human	1.33277241
26	CDX2_19796622_ChIP-Seq_MESCs_Mouse	1.25579818
27	PRDM5_23873026_ChIP-Seq_MEFs_Mouse	1.19569192
28	FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse	1.19019960
29	CDX2_20551321_ChIP-Seq_CACO-2_Human	1.18752275
30	SMAD4_19686287_ChIP-ChIP_HaCaT_Human	1.12365790
31	STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse	1.10859880
32	RXRA_24833708_ChIP-Seq_LIVER_Mouse	1.09534088
33	GLI1_17442700_ChIP-ChIP_MESCs_Mouse	1.09197476
34	NOTCH1_17114293_ChIP-ChIP_T-ALL_Human	1.03960261
35	ZNF217_24962896_ChIP-Seq_MCF-7_Human	1.02540592
36	CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human	1.00446701
37	TP63_17297297_ChIP-ChIP_HaCaT_Human	0.96465475
38	TCF4_18268006_ChIP-ChIP_LS174T_Human	0.95739874
39	THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse	0.95675798
40	TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse	0.95279804
41	GATA6_25053715_ChIP-Seq_YYC3_Human	0.94767798
42	AR_21915096_ChIP-Seq_LNCaP-1F5_Human	0.92662074
43	PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse	0.92390621
44	HIF1A_21447827_ChIP-Seq_MCF-7_Human	0.90562432
45	BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human	0.88654371
46	IRF8_22096565_ChIP-ChIP_GC-B_Human	0.87764733
47	SALL4_18804426_ChIP-ChIP_XEN_Mouse	0.85594028
48	* SOX2_20726797_ChIP-Seq_SW620_Human	0.84520229
49	RARA_24833708_ChIP-Seq_LIVER_Mouse	0.84359030
50	IRF1_21803131_ChIP-Seq_MONOCYTES_Human	0.83875999
51	FOXA1_25329375_ChIP-Seq_VCAP_Human	0.83437392
52	FOXA1_27270436_Chip-Seq_PROSTATE_Human	0.83437392
53	SREBP2_21459322_ChIP-Seq_LIVER_Mouse	0.83107807
54	KAP1_22055183_ChIP-Seq_ESCs_Mouse	0.83029478
55	NR0B1_18358816_ChIP-ChIP_MESCs_Mouse	0.81464817
56	* ESRRB_18555785_ChIP-Seq_MESCs_Mouse	0.80549701
57	* NFE2_27457419_Chip-Seq_LIVER_Mouse	0.79955824
58	FOXA1_25552417_ChIP-Seq_VCAP_Human	0.79628138
59	* FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human	0.79152618
60	ESR2_21235772_ChIP-Seq_MCF-7_Human	0.77726596
61	SREBP1_19666523_ChIP-Seq_LIVER_Mouse	0.77312116
62	PIAS1_25552417_ChIP-Seq_VCAP_Human	0.77268119
63	TFAP2C_20629094_ChIP-Seq_MCF-7_Human	0.75409919
64	FOXA1_21572438_ChIP-Seq_LNCaP_Human	0.74645263
65	RARG_19884340_ChIP-ChIP_MEFs_Mouse	0.73116093
66	PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse	0.73008012
67	PDX1_19855005_ChIP-ChIP_MIN6_Mouse	0.72184550
68	ER_23166858_ChIP-Seq_MCF-7_Human	0.69624182
69	SUZ12_27294783_Chip-Seq_NPCs_Mouse	0.69285752
70	AUTS2_25519132_ChIP-Seq_293T-REX_Human	0.69136551
71	PPARD_23208498_ChIP-Seq_MDA-MB-231_Human	0.68980930
72	ZNF652_21678463_ChIP-ChIP_ZR75-1_Human	0.68908048
73	NCOR_22424771_ChIP-Seq_293T_Human	0.68624489
74	FOXM1_26456572_ChIP-Seq_MCF-7_Human	0.68312457
75	MYC_19829295_ChIP-Seq_ESCs_Human	0.68022547
76	RARB_24833708_ChIP-Seq_LIVER_Mouse	0.67776520
77	POU3F2_20337985_ChIP-ChIP_501MEL_Human	0.67565115
78	BMI1_19503595_ChIP-Seq_MEFsC_Mouse	0.67475086
79	ESR1_21235772_ChIP-Seq_MCF-7_Human	0.67373782
80	AR_20517297_ChIP-Seq_VCAP_Human	0.66421305
81	RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse	0.66107390
82	* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse	0.66101427
83	RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human	0.65645666
84	* GATA3_21867929_ChIP-Seq_CD8_Mouse	0.65560270
85	TRIM28_21343339_ChIP-Seq_HEK293_Human	0.65485664
86	PHF8_20622853_ChIP-Seq_HELA_Human	0.64441307
87	* SOX2_21211035_ChIP-Seq_LN229_Human	0.64140285
88	TCF4_22108803_ChIP-Seq_LS180_Human	0.63954996
89	* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human	0.62776406
90	* RUNX1_27457419_Chip-Seq_LIVER_Mouse	0.61971250
91	* RAD21_21589869_ChIP-Seq_MESCs_Mouse	0.61896468
92	KLF5_20875108_ChIP-Seq_MESCs_Mouse	0.61751317
93	LXR_22292898_ChIP-Seq_THP-1_Human	0.61109180
94	HNFA_21074721_ChIP-Seq_CACO-2_Human	0.60711158
95	FOXH1_21741376_ChIP-Seq_EPCs_Human	0.60573893
96	GBX2_23144817_ChIP-Seq_PC3_Human	0.60473275
97	* STAT3_18555785_Chip-Seq_ESCs_Mouse	0.59796620
98	* PPAR_26484153_Chip-Seq_NCI-H1993_Human	0.59791656
99	* FOXA1_26743006_Chip-Seq_LNCaP-abl_Human	0.59749279
100	PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse	0.59647008
101	* ZFX_18555785_Chip-Seq_ESCs_Mouse	0.59502394
102	EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human	0.58618448
103	NFE2L2_20460467_ChIP-Seq_MEFs_Mouse	0.57585931
104	NRF2_20460467_ChIP-Seq_MEFs_Mouse	0.57585931
105	FOXO3_23340844_ChIP-Seq_DLD1_Human	0.57221939
106	PBX1_22567123_ChIP-ChIP_OVCAR3_Human	0.57015957
107	GATA3_24758297_ChIP-Seq_MCF-7_Human	0.56348226
108	FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human	0.56274387
109	ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human	0.55118423
110	ZNF263_19887448_ChIP-Seq_K562_Human	0.54435524
111	CEBPB_22108803_ChIP-Seq_LS180_Human	0.53772956
112	Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse	0.53699550
113	MYC_19915707_ChIP-ChIP_AK7_Human	0.53675517
114	ESR1_15608294_ChIP-ChIP_MCF-7_Human	0.53295711
115	CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse	0.53245651
116	P53_21459846_ChIP-Seq_SAOS-2_Human	0.52538419
117	GATA1_19941826_ChIP-Seq_K562_Human	0.52492129
118	SRY_22984422_ChIP-ChIP_TESTIS_Rat	0.51459190
119	GATA3_20176728_ChIP-ChIP_TSCs_Mouse	0.51244739
120	ERG_20517297_ChIP-Seq_VCAP_Human	0.51233643
121	CBP_21632823_ChIP-Seq_H3396_Human	0.51021905
122	* GATA2_19941826_ChIP-Seq_K562_Human	0.50697914
123	NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human	0.50502819
124	* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse	0.50417982
125	ESET_19884257_ChIP-Seq_ESCs_Mouse	0.49366687
126	STAT3_1855785_ChIP-Seq_MESCs_Mouse	0.48977543
127	* EBNA1_20929547_Chip-Seq_RAJI-cells_Human	0.48560906
128	STAT1_17558387_ChIP-Seq_HELA_Human	0.47558522
129	ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human	0.45412512
130	EGR1_19032775_ChIP-ChIP_M12_Human	0.44033711
131	CDX2_22108803_ChIP-Seq_LS180_Human	0.44025030
132	RACK7_27058665_Chip-Seq_MCF-7_Human	0.43909173
133	TAF2_19829295_ChIP-Seq_ESCs_Human	0.43481935
134	TET1_21451524_ChIP-Seq_MESCs_Mouse	0.43375890
135	SMAD2/3_21741376_ChIP-Seq_ESCs_Human	0.42462603
136	BCAT_22108803_ChIP-Seq_LS180_Human	0.41357785
137	SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse	0.41283143

Predicted mouse phenotypes (MGI)

Rank	Gene Set	Z-score
1	MP0002139_abnormal_hepatobiliary_system	8.05032318
2	MP0005360_urolithiasis	7.88436255
3	MP0005085_abnormal_gallbladder_physiolo	6.01145207
4	MP0005365_abnormal_bile_salt	5.72194172
5	MP0008875_abnormal_xenobiotic_pharmacok	4.84636885
6	MP0003252_abnormal_bile_duct	3.99882907
7	MP0003806_abnormal_nucleotide_metabolis	3.66838813
8	MP0009840_abnormal_foam_cell	3.52745452
9	MP0010329_abnormal_lipoprotein_level	3.47267925
10	MP0001666_abnormal_nutrient_absorption	3.45165685
11	MP0003195_calcinosis	2.87184079
12	MP0005332_abnormal_amino_acid	2.77952091
13	MP0005083_abnormal_biliary_tract	2.47597135
14	MP0004019_abnormal_vitamin_homeostasis	2.43156246
15	MP0002138_abnormal_hepatobiliary_system	2.31355448
16	MP0003191_abnormal_cellular_cholesterol	2.20793231
17	MP0000609_abnormal_liver_physiology	2.04166597
18	MP0002118_abnormal_lipid_homeostasis	2.03530090
19	MP0003868_abnormal_feces_composition	1.93638526
20	MP0001764_abnormal_homeostasis	1.79945000
21	MP0009697_abnormal_copulation	1.72632549
22	MP0005319_abnormal_enzyme/_coenzyme	1.69062928
23	MP0009643_abnormal_urine_homeostasis	1.59403566
24	MP0005451_abnormal_body_composition	1.43070792
25	MP0003879_abnormal_hair_cell	1.38389091
26	MP0005584_abnormal_enzyme/coenzyme_acti	1.36140054
27	MP0005084_abnormal_gallbladder_morpholo	1.26394712
28	MP0003122_maternal_imprinting	1.26092448
29	MP0005636_abnormal_mineral_homeostasis	1.21585560
30	MP0004043_abnormal_pH_regulation	1.17898214
31	MP0000566_synostosis	1.10798463
32	MP0005220_abnormal_exocrine_pancreas	1.10084620
33	MP0004264_abnormal_extraembryonic_tissu	1.07052015
34	MP0003186_abnormal_redox_activity	1.06434736
35	MP0000598_abnormal_liver_morphology	1.05405118
36	MP0003656_abnormal_erythrocyte_physiolo	1.04789164
37	MP0003123_paternal_imprinting	1.02167430
38	MP0002078_abnormal_glucose_homeostasis	1.02043333
39	MP0001756_abnormal_urination	1.01235745
40	MP0003011_delayed_dark_adaptation	0.98191582
41	MP0002876_abnormal_thyroid_physiology	0.97793111
42	MP0003183_abnormal_peptide_metabolism	0.97706421
43	MP0003705_abnormal_hypodermis_morpholog	0.92075349
44	MP0009642_abnormal_blood_homeostasis	0.91664870
45	MP0005408_hypopigmentation	0.91517425
46	MP0009764_decreased_sensitivity_to	0.90143998
47	MP0002254_reproductive_system_inflammat	0.87430652
48	MP0000604_amyloidosis	0.86784852
49	MP0005647_abnormal_sex_gland	0.86174702
50	MP0010234_abnormal_vibrissa_follicle	0.83944100
51	MP0006036_abnormal_mitochondrial_physio	0.80335492
52	MP0009763_increased_sensitivity_to	0.79174165
53	MP0008469_abnormal_protein_level	0.78576135
54	MP0005376_homeostasis/metabolism_phenot	0.76666839
55	MP0005448_abnormal_energy_balance	0.76568953
56	MP0009765_abnormal_xenobiotic_induced	0.74441078
57	MP0001984_abnormal_olfaction	0.73722201
58	MP0005670_abnormal_white_adipose	0.73655767
59	MP0003300_gastrointestinal_ulcer	0.71711445
60	MP0005535_abnormal_body_temperature	0.71304452
61	MP0005334_abnormal_fat_pad	0.68146461
62	MP0002089_abnormal_postnatal_growth/wei	0.66485432
63	MP0001765_abnormal_ion_homeostasis	0.66014622
64	MP0001944_abnormal_pancreas_morphology	0.65878355
65	MP0002928_abnormal_bile_duct	0.65724512
66	MP0002136_abnormal_kidney_physiology	0.65257764
67	MP0002132_abnormal_respiratory_system	0.65163969
68	MP0002822_catalepsy	0.65139861
69	MP0004270_analgesia	0.64886643
70	MP0002971_abnormal_brown_adipose	0.63928674
71	MP0002837_dystrophic_cardiac_calcinosis	0.63730491
72	MP0000003_abnormal_adipose_tissue	0.62709322
73	MP0005266_abnormal_metabolism	0.61287648
74	MP0000462_abnormal_digestive_system	0.61063255
75	MP0000538_abnormal_urinary_bladder	0.60043194
76	MP0003953_abnormal_hormone_level	0.59403133
77	MP0002090_abnormal_vision	0.56890479
78	MP0000516_abnormal_urinary_system	0.56133904
79	MP0005367_renal/urinary_system_phenotyp	0.56133904
80	MP0003718_maternal_effect	0.55987191
81	MP0009780_abnormal_chondrocyte_physiolo	0.55955287
82	MP0005379_endocrine/exocrine_gland_phen	0.55578051
83	MP0002693_abnormal_pancreas_physiology	0.53911772
84	MP0000639_abnormal_adrenal_gland	0.51946563
85	MP0009046_muscle_twitch	0.51577251
86	MP0003638_abnormal_response/metabolism_	0.50876912
87	MP0005645_abnormal_hypothalamus_physiol	0.50858365
88	MP0000230_abnormal_systemic_arterial	0.50301896
89	MP0009053_abnormal_anal_canal	0.50182816
90	MP0005395_other_phenotype	0.49071932
91	MP0005646_abnormal_pituitary_gland	0.48955478
92	MP0004782_abnormal_surfactant_physiolog	0.47865859
93	MP0005058_abnormal_lysosome_morphology	0.47267933
94	MP0001664_abnormal_digestion	0.45936438
95	MP0001661_extended_life_span	0.45462782
96	MP0005410_abnormal_fertilization	0.44637641
97	MP0010368_abnormal_lymphatic_system	0.44330442
98	MP0003329_amyloid_beta_deposits	0.43707601
99	MP0002796_impaired_skin_barrier	0.42933700
100	MP0006035_abnormal_mitochondrial_morpho	0.42252817
101	MP0008873_increased_physiological_sensi	0.40198523
102	MP0002163_abnormal_gland_morphology	0.40014001
103	MP0005666_abnormal_adipose_tissue	0.39903721
104	MP0003172_abnormal_lysosome_physiology	0.39866803
105	MP0004147_increased_porphyrin_level	0.37661758
106	MP0005248_abnormal_Harderian_gland	0.36796396
107	MP0008874_decreased_physiological_sensi	0.36039925
108	MP0005464_abnormal_platelet_physiology	0.35873534
109	MP0002069_abnormal_eating/drinking_beha	0.35797075
110	MP0004130_abnormal_muscle_cell	0.35465100
111	MP0005551_abnormal_eye_electrophysiolog	0.34994858
112	MP0010386_abnormal_urinary_bladder	0.34811640
113	MP0008872_abnormal_physiological_respon	0.34662018
114	MP0003941_abnormal_skin_development	0.34535553
115	MP0001501_abnormal_sleep_pattern	0.33138118
116	MP0000013_abnormal_adipose_tissue	0.32736491
117	MP0009115_abnormal_fat_cell	0.32282358
118	MP0003690_abnormal_glial_cell	0.32204521
119	MP0002909_abnormal_adrenal_gland	0.31023087
120	MP0005166_decreased_susceptibility_to	0.30591325
121	MP0005381_digestive/alimentary_phenotyp	0.30508803
122	MP0001845_abnormal_inflammatory_respons	0.29959702
123	MP0008961_abnormal_basal_metabolism	0.28746257
124	MP0009384_cardiac_valve_regurgitation	0.26914518
125	MP0003959_abnormal_lean_body	0.26896247

Predicted human phenotypes

Rank	Gene Set	Z-score
1	Abnormality of aromatic amino acid family metabolism (HP:0004338)	7.21880105
2	Intrahepatic cholestasis (HP:0001406)	6.54974424
3	Hypobetalipoproteinemia (HP:0003563)	6.36395835
4	Abnormality of monocarboxylic acid metabolism (HP:0010996)	6.20195855
5	Deep venous thrombosis (HP:0002625)	6.13886724
6	Xanthomatosis (HP:0000991)	5.83506715
7	Prolonged partial thromboplastin time (HP:0003645)	5.75575983
8	Abnormality of glutamine family amino acid metabolism (HP:0010902)	4.68741702
9	Hyperlipoproteinemia (HP:0010980)	4.65488305
10	Hypolipoproteinemia (HP:0010981)	4.59617054
11	Hypoglycemic coma (HP:0001325)	4.53459863
12	Hyperammonemia (HP:0001987)	4.27883262
13	Ketosis (HP:0001946)	4.24915575
14	Abnormality of sulfur amino acid metabolism (HP:0004339)	4.22823800
15	Complement deficiency (HP:0004431)	4.20722212
16	Conjugated hyperbilirubinemia (HP:0002908)	4.18950736
17	Abnormality of aspartate family amino acid metabolism (HP:0010899)	4.15927207
18	Abnormality of the common coagulation pathway (HP:0010990)	4.15133569
19	Fat malabsorption (HP:0002630)	4.14750256
20	Epidermoid cyst (HP:0200040)	4.09837672
21	Abnormality of the level of lipoprotein cholesterol (HP:0010979)	4.07635510
22	Hyperglycinuria (HP:0003108)	4.07488723
23	Joint hemorrhage (HP:0005261)	4.01833418
24	Hyperglycinemia (HP:0002154)	3.97306808
25	Abnormality of the intrinsic pathway (HP:0010989)	3.92109963
26	Abnormality of serine family amino acid metabolism (HP:0010894)	3.82232588
27	Abnormality of glycine metabolism (HP:0010895)	3.82232588
28	Abnormality of methionine metabolism (HP:0010901)	3.80002232
29	Hypoalphalipoproteinemia (HP:0003233)	3.73327701
30	Ketoacidosis (HP:0001993)	3.61463815
31	Abnormality of long-chain fatty-acid metabolism (HP:0010964)	3.43606186
32	Hypercholesterolemia (HP:0003124)	3.40719530
33	Hypoglycemic seizures (HP:0002173)	3.39050174
34	Abnormality of fatty-acid metabolism (HP:0004359)	3.35288876
35	Abnormality of pyrimidine metabolism (HP:0004353)	3.25729571
36	Hyperbilirubinemia (HP:0002904)	3.24189839
37	Abnormality of nucleobase metabolism (HP:0010932)	3.17913046
38	Abnormality of purine metabolism (HP:0004352)	3.14004784
39	Gout (HP:0001997)	3.11257961
40	Hyperinsulinemic hypoglycemia (HP:0000825)	3.08689491
41	Abnormality of complement system (HP:0005339)	3.04197058
42	Acanthocytosis (HP:0001927)	3.02548827
43	Metabolic acidosis (HP:0001942)	2.97213857
44	Symptomatic seizures (HP:0011145)	2.86511261
45	Skin nodule (HP:0200036)	2.82219581
46	Late onset (HP:0003584)	2.79886353
47	Abnormal urine phosphate concentration (HP:0012599)	2.77738869
48	Abnormality of serum amino acid levels (HP:0003112)	2.74928650
49	Malnutrition (HP:0004395)	2.74546934
50	Steatorrhea (HP:0002570)	2.73409484
51	Delayed CNS myelination (HP:0002188)	2.72449939
52	Dicarboxylic aciduria (HP:0003215)	2.68749137
53	Abnormality of dicarboxylic acid metabolism (HP:0010995)	2.68749137
54	Hepatocellular carcinoma (HP:0001402)	2.68074554
55	Lethargy (HP:0001254)	2.59140150
56	Irritability (HP:0000737)	2.56677310
57	Abnormality of urine glucose concentration (HP:0011016)	2.53328858
58	Glycosuria (HP:0003076)	2.53328858
59	Generalized aminoaciduria (HP:0002909)	2.52343511
60	Abnormality of vitamin B metabolism (HP:0004340)	2.50536833
61	Hyperglycemia (HP:0003074)	2.47253497
62	Spontaneous abortion (HP:0005268)	2.43886668
63	Abnormality of proline metabolism (HP:0010907)	2.43223606
64	Hydroxyprolinuria (HP:0003080)	2.43223606
65	Vascular calcification (HP:0004934)	2.39475330
66	Nephritis (HP:0000123)	2.38563672
67	Abnormal gallbladder morphology (HP:0012437)	2.38321419
68	Gingival bleeding (HP:0000225)	2.36041740
69	Proximal tubulopathy (HP:0000114)	2.34377619
70	Facial shape deformation (HP:0011334)	2.32804729
71	Potter facies (HP:0002009)	2.32804729
72	Myocardial infarction (HP:0001658)	2.29456403
73	Systemic lupus erythematosus (HP:0002725)	2.25964092
74	Abnormality of vitamin metabolism (HP:0100508)	2.24796338
75	Hypophosphatemic rickets (HP:0004912)	2.24434984
76	Hypochromic microcytic anemia (HP:0004840)	2.24391268
77	Pancreatitis (HP:0001733)	2.24244984
78	Widely patent fontanelles and sutures (HP:0004492)	2.22770743
79	Cholelithiasis (HP:0001081)	2.22634616
80	Brushfield spots (HP:0001088)	2.17967860
81	Osteomalacia (HP:0002749)	2.16471143
82	Cerebral edema (HP:0002181)	2.16051730
83	Abnormal gallbladder physiology (HP:0012438)	2.14863751
84	Cholecystitis (HP:0001082)	2.14863751
85	Enlarged kidneys (HP:0000105)	2.14844592
86	Alkalosis (HP:0001948)	2.14159529
87	Poikilocytosis (HP:0004447)	2.13724570
88	Reduced antithrombin III activity (HP:0001976)	2.12734803
89	Hypothermia (HP:0002045)	2.10516418
90	Sensorimotor neuropathy (HP:0007141)	2.10443718
91	Cardiovascular calcification (HP:0011915)	2.08457802
92	Vomiting (HP:0002013)	2.08077801
93	Ileus (HP:0002595)	2.07168148
94	Glomerulonephritis (HP:0000099)	2.06087189
95	Hyperuricemia (HP:0002149)	2.05299128
96	Increased purine levels (HP:0004368)	2.05299128
97	Amyloidosis (HP:0011034)	2.03939718
98	Rickets (HP:0002748)	2.03674213
99	Acute encephalopathy (HP:0006846)	2.00206591
100	Abnormality of the pancreatic islet cells (HP:0006476)	1.99795348
101	Abnormality of endocrine pancreas physiology (HP:0012093)	1.99795348
102	Esophageal varix (HP:0002040)	1.99234429
103	Spastic diplegia (HP:0001264)	1.98666082
104	Mitral stenosis (HP:0001718)	1.96541601
105	Abnormal enzyme/coenzyme activity (HP:0012379)	1.95491611
106	Abnormality of the gallbladder (HP:0005264)	1.95424577
107	Hyperphosphaturia (HP:0003109)	1.94937777
108	Hemorrhage of the eye (HP:0011885)	1.94743115
109	Menorrhagia (HP:0000132)	1.94504897
110	Hypotension (HP:0002615)	1.91023310
111	Hypophosphatemia (HP:0002148)	1.90912958
112	Abnormality of the vitamin B12 metabolism (HP:0004341)	1.90733406
113	Abnormality of transition element cation homeostasis (HP:0011030)	1.89703081
114	Neonatal onset (HP:0003623)	1.89462228
115	Nephrolithiasis (HP:0000787)	1.89364260
116	Postural tremor (HP:0002174)	1.89248441
117	Increased serum pyruvate (HP:0003542)	1.88909469
118	Opisthotonus (HP:0002179)	1.87962942
119	Recurrent gram-negative bacterial infections (HP:0005420)	1.84386513
120	Megaloblastic anemia (HP:0001889)	1.82284621
121	Abnormality of glycolysis (HP:0004366)	1.81936975
122	Renal tubular dysfunction (HP:0000124)	1.81561299
123	Mucopolysacchariduria (HP:0008155)	1.77958689
124	Urinary glycosaminoglycan excretion (HP:0003541)	1.77958689

Predicted kinase interactions (KEA)

Rank	Gene Set	Z-score
1	BCKDK	5.81986013
2	MAP3K12	4.72651574
3	FRK	4.52713003
4	INSRR	4.51922048
5	ERN1	4.38285585
6	FGFR4	3.74882147
7	SIK1	3.42099190
8	MAP3K9	3.24777926
9	TAOK3	3.22883497
10	MST1R	2.88521706
11	MAPK15	2.76852137
12	PIK3CG	2.30605087
13	FGFR3	2.30560020
14	ACVR1B	2.25738448
15	SCYL2	2.21314090
16	ERBB4	2.00778273
17	PTK6	1.94732969
18	TESK1	1.85327853
19	AKT3	1.74744109
20	FLT3	1.70700940
21	WNK3	1.69823753
22	NTRK3	1.53816256
23	MAPK11	1.47173205
24	LATS1	1.40038279
25	GRK6	1.39115364
26	MAP3K2	1.38889266
27	MET	1.38003944
28	PKN2	1.36820347
29	TRIB3	1.35352159
30	STK38L	1.34335056
31	WNK4	1.31899131
32	STK39	1.31699476
33	IRAK3	1.29297767
34	MAP2K4	1.29282967
35	PRKG2	1.23692337
36	ARAF	1.23203418
37	MAP2K2	1.20845960
38	PAK4	1.20414340
39	EPHA2	1.19361395
40	DYRK1B	1.18179132
41	MAP3K3	1.12721432
42	CAMK2D	1.12069115
43	PRKAA2	1.10442389
44	TYK2	1.08848269
45	PTK2	1.05287111
46	PHKG1	1.04551618
47	PHKG2	1.04551618
48	RIPK1	1.03793263
49	CSNK1G1	1.03104605
50	LIMK1	0.99725917
51	LMTK2	0.97585719
52	JAK2	0.96785420
53	CASK	0.96014636
54	PRKCI	0.93532467
55	DAPK1	0.93270846
56	EIF2AK1	0.92159808
57	PRKCE	0.91135803
58	DAPK2	0.90529864
59	PRKAA1	0.90027000
60	MAP3K11	0.88587882
61	MAP3K10	0.88194416
62	OXSR1	0.87729601
63	CSNK1G3	0.87197679
64	PINK1	0.84595626
65	MUSK	0.82926525
66	ERBB2	0.80978311
67	MAP2K6	0.78595903
68	GRK5	0.76038481
69	TAOK1	0.75034428
70	NUAK1	0.74444225
71	PBK	0.74122036
72	ABL2	0.74035978
73	JAK1	0.70135672
74	PAK3	0.69658596
75	PRKACG	0.68513552
76	PRKCZ	0.67544706
77	NLK	0.66417074
78	TRPM7	0.65638083
79	CAMK2G	0.65588894
80	NEK9	0.65252833
81	PDPK1	0.64852784
82	PRKG1	0.64668574
83	TBK1	0.64483652
84	MAP3K7	0.64380662
85	MAP3K1	0.64305536
86	TNK2	0.63553529
87	CSNK1E	0.60944586
88	GSK3A	0.60613004
89	EPHB1	0.60189284
90	KDR	0.60108165
91	PASK	0.59808687
92	NEK1	0.59257549
93	CSK	0.58920606
94	TNIK	0.58563816
95	CSNK1G2	0.58235772
96	GRK1	0.54110950
97	RPS6KB2	0.53411448
98	EPHA3	0.53175455
99	MAP2K1	0.52706507
100	MST4	0.51970493
101	ZAK	0.49996070
102	PDK2	0.48156436
103	MAPK4	0.47902657
104	CDK6	0.47876789
105	CSNK1D	0.47481125
106	STK16	0.46837362
107	CSNK1A1L	0.46427164
108	CSNK2A2	0.45917450
109	STK38	0.44636638
110	FGFR1	0.44498620
111	MAP3K4	0.43798732
112	TTK	0.43330866
113	FER	0.42416657
114	AKT2	0.41401696
115	SGK3	0.40882692
116	MAP4K2	0.39925098
117	CAMK2B	0.39737539
118	MAP2K3	0.38714082
119	STK3	0.38582595
120	PDK1	0.36343471
121	FGFR2	0.34973553
122	PRKCQ	0.34404202
123	PRKCA	0.34392018
124	EIF2AK3	0.31618837
125	MTOR	0.30720862
126	IGF1R	0.30660081
127	HIPK2	0.28981997
128	MYLK	0.28764858
129	SGK223	0.28686136
130	SGK494	0.28686136
131	MAP3K14	0.28621677
132	PDK3	0.27969342
133	PDK4	0.27969342
134	MAP3K5	0.25833297
135	PIK3CA	0.24970885
136	ITK	0.24390626
137	SGK2	0.23268266
138	TESK2	0.23237364
139	PDGFRA	0.22561671
140	IRAK1	0.21498011
141	TIE1	0.20746272
142	EPHB2	0.20425833
143	CAMK1D	0.17421111
144	RET	0.17128501
145	PRKACA	0.16419024
146	MAPKAPK3	0.16332880
147	PRKCG	0.16152631
148	CSNK1A1	0.15242956

Predicted pathways (KEGG)

Rank	Gene Set	Z-score
1	Primary bile acid biosynthesis_Homo sapiens_hsa00120	3.95231532
2	Ascorbate and aldarate metabolism_Homo sapiens_hsa00053	3.32361491
3	Nitrogen metabolism_Homo sapiens_hsa00910	3.25059136
4	Arginine biosynthesis_Homo sapiens_hsa00220	3.01087880
5	Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400	2.88371797
6	Tryptophan metabolism_Homo sapiens_hsa00380	2.73783094
7	Fatty acid degradation_Homo sapiens_hsa00071	2.48277943
8	Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630	2.46170548
9	Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280	2.34290762
10	Maturity onset diabetes of the young_Homo sapiens_hsa04950	2.33105111
11	Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040	2.32585343
12	Glycine, serine and threonine metabolism_Homo sapiens_hsa00260	2.32433418
13	Complement and coagulation cascades_Homo sapiens_hsa04610	2.27434491
14	Pentose and glucuronate interconversions_Homo sapiens_hsa00040	2.26401708
15	Butanoate metabolism_Homo sapiens_hsa00650	2.14256488
16	Drug metabolism - cytochrome P450_Homo sapiens_hsa00982	2.04834668
17	Histidine metabolism_Homo sapiens_hsa00340	2.03494396
18	Peroxisome_Homo sapiens_hsa04146	2.01354698
19	Sulfur metabolism_Homo sapiens_hsa00920	1.99580486
20	Fat digestion and absorption_Homo sapiens_hsa04975	1.97672496
21	PPAR signaling pathway_Homo sapiens_hsa03320	1.84077188
22	Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980	1.76737463
23	Caffeine metabolism_Homo sapiens_hsa00232	1.76581429
24	Chemical carcinogenesis_Homo sapiens_hsa05204	1.75440896
25	Folate biosynthesis_Homo sapiens_hsa00790	1.75118490
26	Selenocompound metabolism_Homo sapiens_hsa00450	1.71859091
27	Propanoate metabolism_Homo sapiens_hsa00640	1.71751380
28	Drug metabolism - other enzymes_Homo sapiens_hsa00983	1.71339017
29	Steroid hormone biosynthesis_Homo sapiens_hsa00140	1.69523816
30	Fatty acid metabolism_Homo sapiens_hsa01212	1.68891537
31	Bile secretion_Homo sapiens_hsa04976	1.62428822
32	beta-Alanine metabolism_Homo sapiens_hsa00410	1.61395289
33	Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770	1.58397482
34	Starch and sucrose metabolism_Homo sapiens_hsa00500	1.57849701
35	Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072	1.56082511
36	Retinol metabolism_Homo sapiens_hsa00830	1.54971214
37	Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250	1.52559131
38	2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210	1.52447508
39	Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130	1.49240959
40	Vitamin digestion and absorption_Homo sapiens_hsa04977	1.47825970
41	Phenylalanine metabolism_Homo sapiens_hsa00360	1.45089909
42	Pyruvate metabolism_Homo sapiens_hsa00620	1.39850318
43	Staphylococcus aureus infection_Homo sapiens_hsa05150	1.28326163
44	Tyrosine metabolism_Homo sapiens_hsa00350	1.28037626
45	ABC transporters_Homo sapiens_hsa02010	1.25538232
46	Fatty acid elongation_Homo sapiens_hsa00062	1.21724363
47	Cysteine and methionine metabolism_Homo sapiens_hsa00270	1.15852613
48	Arginine and proline metabolism_Homo sapiens_hsa00330	1.11554171
49	Biosynthesis of amino acids_Homo sapiens_hsa01230	1.11445958
50	Carbon metabolism_Homo sapiens_hsa01200	1.10513500
51	Steroid biosynthesis_Homo sapiens_hsa00100	1.08649335
52	Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524	1.07945756
53	Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964	1.07592315
54	Cyanoamino acid metabolism_Homo sapiens_hsa00460	1.01018379
55	Taurine and hypotaurine metabolism_Homo sapiens_hsa00430	0.93554586
56	Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860	0.91145628
57	Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760	0.88168515
58	Sulfur relay system_Homo sapiens_hsa04122	0.87596309
59	Lysine degradation_Homo sapiens_hsa00310	0.81367672
60	Glycerolipid metabolism_Homo sapiens_hsa00561	0.80565396
61	Glutathione metabolism_Homo sapiens_hsa00480	0.80531707
62	Citrate cycle (TCA cycle)_Homo sapiens_hsa00020	0.77228009
63	Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010	0.75208251
64	Vitamin B6 metabolism_Homo sapiens_hsa00750	0.74753766
65	Galactose metabolism_Homo sapiens_hsa00052	0.70938108
66	Pentose phosphate pathway_Homo sapiens_hsa00030	0.65958777
67	Fructose and mannose metabolism_Homo sapiens_hsa00051	0.65382018
68	Metabolic pathways_Homo sapiens_hsa01100	0.53260568
69	One carbon pool by folate_Homo sapiens_hsa00670	0.51624094
70	Sphingolipid metabolism_Homo sapiens_hsa00600	0.51116847
71	Renin-angiotensin system_Homo sapiens_hsa04614	0.50330562
72	Oxidative phosphorylation_Homo sapiens_hsa00190	0.48587725
73	Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520	0.38758978
74	alpha-Linolenic acid metabolism_Homo sapiens_hsa00592	0.38350039
75	Carbohydrate digestion and absorption_Homo sapiens_hsa04973	0.35489091
76	Mineral absorption_Homo sapiens_hsa04978	0.35108532
77	Linoleic acid metabolism_Homo sapiens_hsa00591	0.32781974
78	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563	0.32712411
79	Fatty acid biosynthesis_Homo sapiens_hsa00061	0.32147122
80	Glycerophospholipid metabolism_Homo sapiens_hsa00564	0.28285237
81	Insulin resistance_Homo sapiens_hsa04931	0.25984106
82	Prion diseases_Homo sapiens_hsa05020	0.23300865
83	Ether lipid metabolism_Homo sapiens_hsa00565	0.20605453
84	Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141	0.20439796
85	Protein export_Homo sapiens_hsa03060	0.18446865
86	Pancreatic secretion_Homo sapiens_hsa04972	0.16417897
87	Serotonergic synapse_Homo sapiens_hsa04726	0.15229463
88	Parkinsons disease_Homo sapiens_hsa05012	0.14171536
89	Adipocytokine signaling pathway_Homo sapiens_hsa04920	0.13600523
90	Terpenoid backbone biosynthesis_Homo sapiens_hsa00900	0.13074479
91	Protein digestion and absorption_Homo sapiens_hsa04974	0.12458134
92	Glucagon signaling pathway_Homo sapiens_hsa04922	0.11289784
93	Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601	0.10764690
94	Vibrio cholerae infection_Homo sapiens_hsa05110	0.10539648
95	Alzheimers disease_Homo sapiens_hsa05010	0.10367301
96	Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932	0.06133991
97	Thyroid hormone synthesis_Homo sapiens_hsa04918	0.04427450
98	AMPK signaling pathway_Homo sapiens_hsa04152	0.01073995
99	Lysosome_Homo sapiens_hsa04142	-0.1618859
100	Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604	-0.1519355
101	Hepatitis C_Homo sapiens_hsa05160	-0.1367390
102	Ovarian steroidogenesis_Homo sapiens_hsa04913	-0.1302605
103	Insulin signaling pathway_Homo sapiens_hsa04910	-0.1189326
104	N-Glycan biosynthesis_Homo sapiens_hsa00510	-0.1178988
105	Other glycan degradation_Homo sapiens_hsa00511	-0.1141696
106	Insulin secretion_Homo sapiens_hsa04911	-0.1133805
107	Glycosaminoglycan degradation_Homo sapiens_hsa00531	-0.0686120
108	Type II diabetes mellitus_Homo sapiens_hsa04930	-0.0663842
109	Regulation of autophagy_Homo sapiens_hsa04140	-0.0655713
110	Arachidonic acid metabolism_Homo sapiens_hsa00590	-0.0115161

GOLT1A

Functional Annotation Prediction

Predicted biological processes (GO)

Predicted upstream transcription factors (ChEA)

Predicted mouse phenotypes (MGI)

Predicted human phenotypes

Predicted kinase interactions (KEA)

Predicted pathways (KEGG)

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