GOLT1B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1signal peptide processing (GO:0006465)6.10932263
2cullin deneddylation (GO:0010388)5.11305998
3protein deneddylation (GO:0000338)4.65174592
4COPI coating of Golgi vesicle (GO:0048205)4.58666738
5Golgi transport vesicle coating (GO:0048200)4.58666738
6ribosome assembly (GO:0042255)4.49414413
7regulation of protein glycosylation (GO:0060049)4.46639183
8protein neddylation (GO:0045116)4.43584533
9maintenance of protein localization in endoplasmic reticulum (GO:0035437)4.03563100
10IMP biosynthetic process (GO:0006188)3.82034028
11purine nucleobase biosynthetic process (GO:0009113)3.81304940
12acrosome assembly (GO:0001675)3.72485855
13rRNA methylation (GO:0031167)3.71847173
14protein retention in ER lumen (GO:0006621)3.62380345
15nucleobase biosynthetic process (GO:0046112)3.60245380
16transcription from mitochondrial promoter (GO:0006390)3.54653999
172-deoxyribonucleotide biosynthetic process (GO:0009265)3.52476213
18deoxyribose phosphate biosynthetic process (GO:0046385)3.52476213
19rRNA modification (GO:0000154)3.51952289
20ER overload response (GO:0006983)3.51582471
21histone mRNA metabolic process (GO:0008334)3.46080866
22somatic diversification of immunoglobulins involved in immune response (GO:0002208)3.42909973
23isotype switching (GO:0045190)3.42909973
24somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)3.42909973
25deoxyribonucleotide biosynthetic process (GO:0009263)3.42491148
26COPII vesicle coating (GO:0048208)3.35417600
27establishment of protein localization to mitochondrial membrane (GO:0090151)3.34498666
28DNA double-strand break processing (GO:0000729)3.33065448
29platelet dense granule organization (GO:0060155)3.32430229
30proteasome assembly (GO:0043248)3.29528760
31exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.28773599
327-methylguanosine mRNA capping (GO:0006370)3.28426034
33tRNA aminoacylation for protein translation (GO:0006418)3.28149668
34amino acid activation (GO:0043038)3.25748234
35tRNA aminoacylation (GO:0043039)3.25748234
36negative regulation of DNA-dependent DNA replication (GO:2000104)3.24280816
37RNA capping (GO:0036260)3.23400639
387-methylguanosine RNA capping (GO:0009452)3.23400639
39mitotic metaphase plate congression (GO:0007080)3.22133094
40negative regulation of ligase activity (GO:0051352)3.21693587
41negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.21693587
42response to X-ray (GO:0010165)3.21533299
43anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.19040716
44establishment of integrated proviral latency (GO:0075713)3.18724160
45nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.18512413
46RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.18336325
47lactate metabolic process (GO:0006089)3.16621819
48attachment of spindle microtubules to kinetochore (GO:0008608)3.16290420
49viral mRNA export from host cell nucleus (GO:0046784)3.16071653
50negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902254)3.13526453
51positive regulation of protein autophosphorylation (GO:0031954)3.10300388
52metaphase plate congression (GO:0051310)3.06971410
53regulation of glucokinase activity (GO:0033131)3.06722393
54regulation of hexokinase activity (GO:1903299)3.06722393
55establishment of viral latency (GO:0019043)3.06474582
56transcription from RNA polymerase I promoter (GO:0006360)3.05367023
57regulation of cellular amino acid metabolic process (GO:0006521)3.04417739
58RNA-dependent DNA replication (GO:0006278)3.04049479
59telomere maintenance via semi-conservative replication (GO:0032201)3.04020112
60heart process (GO:0003015)3.03154455
61heart contraction (GO:0060047)3.03154455
62non-recombinational repair (GO:0000726)3.02950442
63double-strand break repair via nonhomologous end joining (GO:0006303)3.02950442
64deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.98012991
65histone exchange (GO:0043486)2.97744328
66viral protein processing (GO:0019082)2.97228259
67telomere maintenance via recombination (GO:0000722)2.96094663
68protein K11-linked ubiquitination (GO:0070979)2.95863631
69regulation of nuclear cell cycle DNA replication (GO:0033262)2.94694394
70UDP-N-acetylglucosamine metabolic process (GO:0006047)2.94185957
71regulation of mitotic spindle checkpoint (GO:1903504)2.93010139
72regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.93010139
73transcription initiation from RNA polymerase I promoter (GO:0006361)2.92512361
74peptidyl-histidine modification (GO:0018202)2.91106661
75intraciliary transport (GO:0042073)2.90589368
76transcription-coupled nucleotide-excision repair (GO:0006283)2.90319535
77mitochondrial RNA metabolic process (GO:0000959)2.89964322
78DNA catabolic process, exonucleolytic (GO:0000738)2.88042310
79DNA deamination (GO:0045006)2.87903919
80DNA replication checkpoint (GO:0000076)2.87814661
81nuclear pore complex assembly (GO:0051292)2.87548997
82formation of translation preinitiation complex (GO:0001731)2.86997364
83positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.86219239
84respiratory chain complex IV assembly (GO:0008535)2.86100015
85nuclear pore organization (GO:0006999)2.85386595
86transcription elongation from RNA polymerase I promoter (GO:0006362)2.84996433
87mitotic spindle checkpoint (GO:0071174)2.83871000
88IMP metabolic process (GO:0046040)2.83158510
89CENP-A containing nucleosome assembly (GO:0034080)2.82489761
90spindle checkpoint (GO:0031577)2.82092099
91dolichol-linked oligosaccharide biosynthetic process (GO:0006488)2.80511216
92termination of RNA polymerase III transcription (GO:0006386)2.79695853
93transcription elongation from RNA polymerase III promoter (GO:0006385)2.79695853
94GMP metabolic process (GO:0046037)2.76965297
95ribonucleoprotein complex disassembly (GO:0032988)2.75702636
96mitotic recombination (GO:0006312)2.75629286
97negative regulation of dendrite morphogenesis (GO:0050774)2.75392318
98deoxyribonucleoside diphosphate metabolic process (GO:0009186)2.74654190
99positive regulation of ligase activity (GO:0051351)2.74356952
100organelle disassembly (GO:1903008)2.74110843
101negative regulation of mast cell activation (GO:0033004)2.72191974
102nucleobase-containing small molecule interconversion (GO:0015949)2.72092313
103regulation of ubiquitin-protein transferase activity (GO:0051438)2.71417313
104antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.71092482
105negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.71000443
106negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.71000443
107negative regulation of mitotic sister chromatid segregation (GO:0033048)2.71000443
108negative regulation of mitotic sister chromatid separation (GO:2000816)2.71000443
109negative regulation of sister chromatid segregation (GO:0033046)2.71000443
110regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.70632266
111regulation of mitotic metaphase/anaphase transition (GO:0030071)2.70632266
112negative regulation of signal transduction by p53 class mediator (GO:1901797)2.70312614
113single strand break repair (GO:0000012)2.69278706
114positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.68471325
115termination of RNA polymerase I transcription (GO:0006363)2.68112426
116water-soluble vitamin biosynthetic process (GO:0042364)2.67794635
117DNA strand elongation involved in DNA replication (GO:0006271)2.67396063
118signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.65954165
119signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.65954165
120signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.65954165
121ribosome biogenesis (GO:0042254)2.65891637
122negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.65594862
123DNA strand elongation (GO:0022616)2.65524976
124regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902253)2.65452078
125sequestering of actin monomers (GO:0042989)2.65450737
126DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.65267549
127chromatin remodeling at centromere (GO:0031055)2.64472921
128maturation of 5.8S rRNA (GO:0000460)2.64418331
129regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.64326431
130antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.63499714
131nucleotide-excision repair, DNA gap filling (GO:0006297)2.62543864
132regulation of ligase activity (GO:0051340)2.62020505
133DNA ligation (GO:0006266)2.61993004
134histone H2A acetylation (GO:0043968)2.61892841
135pore complex assembly (GO:0046931)2.61168948
136negative regulation of keratinocyte proliferation (GO:0010839)2.61063927
137G1/S transition of mitotic cell cycle (GO:0000082)2.60091939
138cell cycle G1/S phase transition (GO:0044843)2.60091939
139signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.59991393
140intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.59991393
141establishment of chromosome localization (GO:0051303)2.59794905
142transcription elongation from RNA polymerase II promoter (GO:0006368)2.59283214
143DNA damage response, detection of DNA damage (GO:0042769)2.58916949
144DNA-dependent DNA replication (GO:0006261)2.58367812
145negative regulation of chromosome segregation (GO:0051985)2.57822186
146regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.56688800
147kinetochore organization (GO:0051383)2.56627080
148chaperone-mediated protein folding (GO:0061077)2.54472021
149DNA replication initiation (GO:0006270)2.54016328
150negative regulation of release of cytochrome c from mitochondria (GO:0090201)2.53888940
151nucleotide-sugar biosynthetic process (GO:0009226)2.53878988
152GDP-mannose metabolic process (GO:0019673)2.53632513
153sequestering of metal ion (GO:0051238)2.53375374
154guanosine-containing compound biosynthetic process (GO:1901070)2.53369276
155signal transduction involved in cell cycle checkpoint (GO:0072395)2.52649984
156protein peptidyl-prolyl isomerization (GO:0000413)2.51733906
157regulation of double-strand break repair via homologous recombination (GO:0010569)2.49979368
158antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.49579860
159cytochrome complex assembly (GO:0017004)2.48876892
160signal transduction involved in DNA integrity checkpoint (GO:0072401)2.48585730
161signal transduction involved in DNA damage checkpoint (GO:0072422)2.48585730
162tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.48383374
163RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.48383374
164regulation of transcription from RNA polymerase I promoter (GO:0006356)2.47106985

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* E2F7_22180533_ChIP-Seq_HELA_Human4.98634805
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.85998834
3RBPJ_22232070_ChIP-Seq_NCS_Mouse4.20359845
4GABP_17652178_ChIP-ChIP_JURKAT_Human3.43649352
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.31840609
6E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.20508694
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.06618895
8ELK1_19687146_ChIP-ChIP_HELA_Human2.91449084
9CREB1_15753290_ChIP-ChIP_HEK293T_Human2.85237212
10HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.83723164
11PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.75207745
12MYC_18555785_ChIP-Seq_MESCs_Mouse2.49203454
13NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.44135166
14PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.42146574
15SRF_21415370_ChIP-Seq_HL-1_Mouse2.35435543
16* ELF1_17652178_ChIP-ChIP_JURKAT_Human2.32910442
17* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.30707097
18* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.29770333
19HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.26192385
20* E2F4_17652178_ChIP-ChIP_JURKAT_Human2.21739421
21VDR_23849224_ChIP-Seq_CD4+_Human2.20084037
22CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.19793415
23* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.13421790
24KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.07521700
25ETS1_20019798_ChIP-Seq_JURKAT_Human2.06629424
26NELFA_20434984_ChIP-Seq_ESCs_Mouse2.06597354
27FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.91445509
28YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.90701937
29FLI1_27457419_Chip-Seq_LIVER_Mouse1.81069089
30DCP1A_22483619_ChIP-Seq_HELA_Human1.81043047
31THAP11_20581084_ChIP-Seq_MESCs_Mouse1.80006636
32TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.77975410
33* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.77407491
34MYC_18358816_ChIP-ChIP_MESCs_Mouse1.76992895
35E2F1_18555785_ChIP-Seq_MESCs_Mouse1.73462143
36* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.71185996
37P300_19829295_ChIP-Seq_ESCs_Human1.68036541
38SMAD_19615063_ChIP-ChIP_OVARY_Human1.67791998
39PADI4_21655091_ChIP-ChIP_MCF-7_Human1.64467200
40SALL1_21062744_ChIP-ChIP_HESCs_Human1.63613893
41VDR_22108803_ChIP-Seq_LS180_Human1.61864123
42MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.61687757
43E2F1_21310950_ChIP-Seq_MCF-7_Human1.60041129
44FOXP3_21729870_ChIP-Seq_TREG_Human1.59952308
45PCGF2_27294783_Chip-Seq_ESCs_Mouse1.59695880
46FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.57773129
47YY1_21170310_ChIP-Seq_MESCs_Mouse1.55012257
48ZNF274_21170338_ChIP-Seq_K562_Hela1.54879846
49* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.54583194
50DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.53989666
51MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.53394373
52MYCN_18555785_ChIP-Seq_MESCs_Mouse1.50529819
53MYC_18940864_ChIP-ChIP_HL60_Human1.49214201
54GABP_19822575_ChIP-Seq_HepG2_Human1.48118802
55PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.47624540
56EWS_26573619_Chip-Seq_HEK293_Human1.40537596
57TAF15_26573619_Chip-Seq_HEK293_Human1.38025945
58POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.37813167
59TP63_19390658_ChIP-ChIP_HaCaT_Human1.36398426
60AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.34672606
61CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.33056155
62SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.32808715
63POU5F1_16153702_ChIP-ChIP_HESCs_Human1.30183074
64PCGF2_27294783_Chip-Seq_NPCs_Mouse1.27396865
65IGF1R_20145208_ChIP-Seq_DFB_Human1.25753948
66MYC_19079543_ChIP-ChIP_MESCs_Mouse1.25713074
67ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.25270961
68NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.24612432
69BRD4_25478319_ChIP-Seq_HGPS_Human1.22536188
70ERG_20887958_ChIP-Seq_HPC-7_Mouse1.21329611
71AR_21909140_ChIP-Seq_LNCAP_Human1.20085288
72CRX_20693478_ChIP-Seq_RETINA_Mouse1.19615344
73IRF1_19129219_ChIP-ChIP_H3396_Human1.19136694
74SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.18345042
75TTF2_22483619_ChIP-Seq_HELA_Human1.18243962
76NOTCH1_21737748_ChIP-Seq_TLL_Human1.16868698
77CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.15421995
78ELK1_22589737_ChIP-Seq_MCF10A_Human1.15420687
79ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.15002022
80CDX2_22108803_ChIP-Seq_LS180_Human1.13510811
81ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.12503991
82IRF8_22096565_ChIP-ChIP_GC-B_Human1.12198467
83WT1_19549856_ChIP-ChIP_CCG9911_Human1.11128066
84TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.10668498
85CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.09244006
86STAT3_18555785_Chip-Seq_ESCs_Mouse1.08182045
87OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.07832896
88ZFP57_27257070_Chip-Seq_ESCs_Mouse1.07354454
89UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.06780036
90SOX2_19829295_ChIP-Seq_ESCs_Human1.05849684
91NANOG_19829295_ChIP-Seq_ESCs_Human1.05849684
92* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.04372241
93FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.04049436
94CMYC_18555785_Chip-Seq_ESCs_Mouse1.03128071
95XRN2_22483619_ChIP-Seq_HELA_Human1.02579787
96SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.01870423
97GATA4_21415370_ChIP-Seq_HL-1_Mouse1.01818526
98SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.01794147
99POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.01767639
100SOX17_20123909_ChIP-Seq_XEN_Mouse1.01628833
101SUZ12_27294783_Chip-Seq_NPCs_Mouse1.01515038
102NFE2_27457419_Chip-Seq_LIVER_Mouse1.00926983
103NANOG_18555785_ChIP-Seq_MESCs_Mouse1.00289702
104OCT4_21477851_ChIP-Seq_ESCs_Mouse1.00272395
105P300_18555785_Chip-Seq_ESCs_Mouse0.99980259
106TFEB_21752829_ChIP-Seq_HELA_Human0.99595008
107FUS_26573619_Chip-Seq_HEK293_Human0.99241907
108MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.97882052
109FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.97865599
110SOX2_18555785_ChIP-Seq_MESCs_Mouse0.97820153
111NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.97787415
112NRF2_20460467_ChIP-Seq_MEFs_Mouse0.97787415
113SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.97613663
114NANOG_16153702_ChIP-ChIP_HESCs_Human0.95430535
115MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.94229377
116CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.94002962
117CTBP2_25329375_ChIP-Seq_LNCAP_Human0.93999285
118E2F1_18555785_Chip-Seq_ESCs_Mouse0.93728317
119ER_23166858_ChIP-Seq_MCF-7_Human0.93572826
120IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.93433478
121CBP_20019798_ChIP-Seq_JUKART_Human0.93141075
122IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.93141075
123NMYC_18555785_Chip-Seq_ESCs_Mouse0.93061910
124GBX2_23144817_ChIP-Seq_PC3_Human0.93033731
125P53_22387025_ChIP-Seq_ESCs_Mouse0.92642424
126ZFX_18555785_ChIP-Seq_MESCs_Mouse0.92214321
127TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.90413331
128NANOG_18555785_Chip-Seq_ESCs_Mouse0.89696458
129EGR1_19374776_ChIP-ChIP_THP-1_Human0.89614885
130EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.89062233
131EZH2_27294783_Chip-Seq_NPCs_Mouse0.89040543
132* RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.88440460
133SUZ12_18555785_Chip-Seq_ESCs_Mouse0.87785644
134GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.86625987
135CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.86549620
136BMI1_23680149_ChIP-Seq_NPCS_Mouse0.84120172
137NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.83681300

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004272_abnormal_basement_membrane3.60550502
2MP0002877_abnormal_melanocyte_morpholog2.86657805
3MP0008007_abnormal_cellular_replicative2.75795716
4MP0008057_abnormal_DNA_replication2.68649947
5MP0003693_abnormal_embryo_hatching2.67251749
6MP0005503_abnormal_tendon_morphology2.51480682
7MP0002102_abnormal_ear_morphology2.50055186
8MP0000566_synostosis2.48434389
9MP0003950_abnormal_plasma_membrane2.41797606
10MP0008058_abnormal_DNA_repair2.37809943
11MP0003806_abnormal_nucleotide_metabolis2.34720881
12MP0009697_abnormal_copulation2.32547139
13MP0002163_abnormal_gland_morphology2.31396586
14MP0010094_abnormal_chromosome_stability2.25733696
15MP0003123_paternal_imprinting2.20369603
16MP0006054_spinal_hemorrhage2.13447606
17MP0000678_abnormal_parathyroid_gland2.09577982
18MP0005367_renal/urinary_system_phenotyp2.08944964
19MP0000516_abnormal_urinary_system2.08944964
20MP0003786_premature_aging2.07522225
21MP0005646_abnormal_pituitary_gland2.06455795
22MP0004782_abnormal_surfactant_physiolog2.06192268
23MP0003122_maternal_imprinting2.03368012
24MP0001188_hyperpigmentation2.03269778
25MP0010386_abnormal_urinary_bladder2.00326102
26MP0000015_abnormal_ear_pigmentation1.98200820
27MP0003121_genomic_imprinting1.91736041
28MP0004957_abnormal_blastocyst_morpholog1.83836310
29MP0001542_abnormal_bone_strength1.80864246
30MP0001984_abnormal_olfaction1.79023451
31MP0002876_abnormal_thyroid_physiology1.75741956
32MP0000647_abnormal_sebaceous_gland1.71995101
33MP0003787_abnormal_imprinting1.70728901
34MP0003077_abnormal_cell_cycle1.69397634
35MP0006072_abnormal_retinal_apoptosis1.67563743
36MP0006292_abnormal_olfactory_placode1.67411810
37MP0010234_abnormal_vibrissa_follicle1.63849941
38MP0005379_endocrine/exocrine_gland_phen1.63324561
39MP0002160_abnormal_reproductive_system1.62766884
40MP0001986_abnormal_taste_sensitivity1.62279004
41MP0000049_abnormal_middle_ear1.61456374
42MP0003567_abnormal_fetal_cardiomyocyte1.61102601
43MP0008932_abnormal_embryonic_tissue1.60709696
44MP0005171_absent_coat_pigmentation1.59125815
45MP0005408_hypopigmentation1.59066295
46MP0002090_abnormal_vision1.57505613
47MP0002751_abnormal_autonomic_nervous1.56566794
48MP0004215_abnormal_myocardial_fiber1.54756677
49MP0010030_abnormal_orbit_morphology1.53988760
50MP0008438_abnormal_cutaneous_collagen1.52731154
51MP0004134_abnormal_chest_morphology1.51119769
52MP0009250_abnormal_appendicular_skeleto1.46607022
53MP0008877_abnormal_DNA_methylation1.46271645
54MP0009053_abnormal_anal_canal1.45071819
55MP0003111_abnormal_nucleus_morphology1.44346086
56MP0000427_abnormal_hair_cycle1.42854551
57MP0010352_gastrointestinal_tract_polyps1.42831814
58MP0003943_abnormal_hepatobiliary_system1.40643942
59MP0002009_preneoplasia1.38020713
60MP0005389_reproductive_system_phenotype1.37373187
61MP0001919_abnormal_reproductive_system1.36035244
62MP0003941_abnormal_skin_development1.35862199
63MP0000372_irregular_coat_pigmentation1.33299447
64MP0005508_abnormal_skeleton_morphology1.31230931
65MP0001177_atelectasis1.29839240
66MP0003183_abnormal_peptide_metabolism1.24513752
67MP0002938_white_spotting1.22014772
68MP0003942_abnormal_urinary_system1.20623401
69MP0001293_anophthalmia1.18374805
70MP0003186_abnormal_redox_activity1.18097994
71MP0003221_abnormal_cardiomyocyte_apopto1.17843881
72MP0003890_abnormal_embryonic-extraembry1.15966857
73MP0001730_embryonic_growth_arrest1.13060425
74MP0000358_abnormal_cell_content/1.13004276
75MP0001879_abnormal_lymphatic_vessel1.12576051
76MP0010678_abnormal_skin_adnexa1.12487206
77MP0000681_abnormal_thyroid_gland1.11889085
78MP0001119_abnormal_female_reproductive1.10651819
79MP0008789_abnormal_olfactory_epithelium1.10001643
80MP0003195_calcinosis1.07237533
81MP0001661_extended_life_span1.07039841
82MP0001186_pigmentation_phenotype1.06168501
83MP0000163_abnormal_cartilage_morphology1.05728995
84MP0003755_abnormal_palate_morphology1.04956820
85MP0001697_abnormal_embryo_size1.04378873
86MP0003315_abnormal_perineum_morphology1.03838852
87MP0005084_abnormal_gallbladder_morpholo1.03343766
88MP0005253_abnormal_eye_physiology1.02284193
89MP0002233_abnormal_nose_morphology1.02135993
90MP0005390_skeleton_phenotype1.00612032
91MP0002177_abnormal_outer_ear0.99454664
92MP0002084_abnormal_developmental_patter0.99171374
93MP0002109_abnormal_limb_morphology0.98897660
94MP0000371_diluted_coat_color0.97612342
95MP0001191_abnormal_skin_condition0.97464871
96MP0001529_abnormal_vocalization0.97024535
97MP0003448_altered_tumor_morphology0.96610951
98MP0005623_abnormal_meninges_morphology0.94975951
99MP0002254_reproductive_system_inflammat0.94939327
100MP0005380_embryogenesis_phenotype0.94531430
101MP0001299_abnormal_eye_distance/0.94249327
102MP0002295_abnormal_pulmonary_circulatio0.93919128
103MP0000350_abnormal_cell_proliferation0.93220269
104MP0002115_abnormal_skeleton_extremities0.93173650
105MP0006036_abnormal_mitochondrial_physio0.92970319
106MP0002638_abnormal_pupillary_reflex0.91518579
107MP0002396_abnormal_hematopoietic_system0.90063832
108MP0000013_abnormal_adipose_tissue0.86934816
109MP0002113_abnormal_skeleton_development0.86230984
110MP0009780_abnormal_chondrocyte_physiolo0.85251314
111MP0009703_decreased_birth_body0.84566753
112MP0002693_abnormal_pancreas_physiology0.84394721
113MP0005384_cellular_phenotype0.83982483
114MP0010307_abnormal_tumor_latency0.81154382
115MP0002085_abnormal_embryonic_tissue0.80489503
116MP0006035_abnormal_mitochondrial_morpho0.80151858
117MP0002148_abnormal_hypersensitivity_rea0.79215860
118MP0005551_abnormal_eye_electrophysiolog0.78338222
119MP0004133_heterotaxia0.78279973
120MP0003385_abnormal_body_wall0.77895576
121MP0002116_abnormal_craniofacial_bone0.76907429
122MP0002086_abnormal_extraembryonic_tissu0.76795844
123MP0003279_aneurysm0.74923712
124MP0003718_maternal_effect0.74619119
125MP0002933_joint_inflammation0.74464897
126MP0001243_abnormal_dermal_layer0.74432222
127MP0005275_abnormal_skin_tensile0.74317521
128MP0001835_abnormal_antigen_presentation0.73781300
129MP0002095_abnormal_skin_pigmentation0.72787102
130MP0004197_abnormal_fetal_growth/weight/0.72326650
131MP0003868_abnormal_feces_composition0.72171789
132MP0005645_abnormal_hypothalamus_physiol0.71987447
133MP0002088_abnormal_embryonic_growth/wei0.71978622
134MP0005621_abnormal_cell_physiology0.70701834
135MP0003984_embryonic_growth_retardation0.70430529
136MP0005395_other_phenotype0.70170770
137MP0003795_abnormal_bone_structure0.70095146
138MP0004084_abnormal_cardiac_muscle0.69729183
139MP0003937_abnormal_limbs/digits/tail_de0.69713736
140MP0003119_abnormal_digestive_system0.68341492
141MP0002127_abnormal_cardiovascular_syste0.67854490
142MP0002060_abnormal_skin_morphology0.67539255
143MP0002282_abnormal_trachea_morphology0.65855551
144MP0005394_taste/olfaction_phenotype0.63436896
145MP0005499_abnormal_olfactory_system0.63436896
146MP0001764_abnormal_homeostasis0.63422336
147MP0002132_abnormal_respiratory_system0.61419796
148MP0001672_abnormal_embryogenesis/_devel0.60729128

Predicted human phenotypes

RankGene SetZ-score
1Irregular epiphyses (HP:0010582)4.71702669
2Type II lissencephaly (HP:0007260)4.53573334
3Calf muscle hypertrophy (HP:0008981)3.88015388
4Type I transferrin isoform profile (HP:0003642)3.74851178
5Degeneration of anterior horn cells (HP:0002398)3.50969107
6Abnormality of the anterior horn cell (HP:0006802)3.50969107
7Birth length less than 3rd percentile (HP:0003561)3.41334743
8Entropion (HP:0000621)3.30512124
9Flat capital femoral epiphysis (HP:0003370)3.30117367
10Retinal dysplasia (HP:0007973)3.29528778
11Muscle hypertrophy of the lower extremities (HP:0008968)3.24236996
12True hermaphroditism (HP:0010459)3.15257983
13Epiphyseal dysplasia (HP:0002656)2.97394049
14Abnormality of incisor morphology (HP:0011063)2.89491155
15Vitreoretinal degeneration (HP:0000655)2.88839406
1611 pairs of ribs (HP:0000878)2.85699434
17Methylmalonic acidemia (HP:0002912)2.79293993
18Increased serum pyruvate (HP:0003542)2.78174880
19Abnormality of glycolysis (HP:0004366)2.76621394
20Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.69898985
21Abnormal protein N-linked glycosylation (HP:0012347)2.69898985
22Abnormal protein glycosylation (HP:0012346)2.69898985
23Abnormal glycosylation (HP:0012345)2.69898985
24Hypothermia (HP:0002045)2.66462107
25Abnormality of methionine metabolism (HP:0010901)2.64396046
26Volvulus (HP:0002580)2.64023275
27Pancreatic fibrosis (HP:0100732)2.59619347
28Long clavicles (HP:0000890)2.54596852
29Chromsome breakage (HP:0040012)2.52627823
30Sensory axonal neuropathy (HP:0003390)2.50974256
31Carpal bone hypoplasia (HP:0001498)2.50507390
32Acute necrotizing encephalopathy (HP:0006965)2.50096627
33Chromosomal breakage induced by crosslinking agents (HP:0003221)2.48771882
34Bifid tongue (HP:0010297)2.47820536
35Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.45614834
36Absent epiphyses (HP:0010577)2.45614834
37Abnormality of the metopic suture (HP:0005556)2.44561353
38Progressive macrocephaly (HP:0004481)2.42098296
39Abnormality of aspartate family amino acid metabolism (HP:0010899)2.40894381
40Abnormal pancreas size (HP:0012094)2.40701474
41Abnormal hair whorl (HP:0010721)2.39990178
42Abnormality of femoral epiphyses (HP:0006499)2.39546235
43Abnormality involving the epiphyses of the lower limbs (HP:0006500)2.39546235
44Delayed epiphyseal ossification (HP:0002663)2.39020251
45Small epiphyses (HP:0010585)2.38374819
46Abnormality of the femoral head (HP:0003368)2.35879905
47Postnatal microcephaly (HP:0005484)2.35159241
48Duodenal stenosis (HP:0100867)2.34243232
49Small intestinal stenosis (HP:0012848)2.34243232
50Embryonal renal neoplasm (HP:0011794)2.33408993
51Abnormality of the epiphysis of the femoral head (HP:0010574)2.32050772
52Abnormality of the pons (HP:0007361)2.30563165
53Nephroblastoma (Wilms tumor) (HP:0002667)2.29682557
54Poikiloderma (HP:0001029)2.29610509
55Alveolar cell carcinoma (HP:0006519)2.29536438
56Intestinal atresia (HP:0011100)2.28585161
57Acute encephalopathy (HP:0006846)2.28091414
58Spinal cord lesions (HP:0100561)2.27298472
59Syringomyelia (HP:0003396)2.27298472
60Methylmalonic aciduria (HP:0012120)2.24241432
613-Methylglutaconic aciduria (HP:0003535)2.23714998
62Patent foramen ovale (HP:0001655)2.23551784
63Increased CSF lactate (HP:0002490)2.22786967
64Hypoplasia of the fovea (HP:0007750)2.22693179
65Aplasia/Hypoplasia of the fovea (HP:0008060)2.22693179
66Thyroid carcinoma (HP:0002890)2.22660558
67Papillary thyroid carcinoma (HP:0002895)2.22139353
68Premature rupture of membranes (HP:0001788)2.21526084
69Biliary tract neoplasm (HP:0100574)2.20878787
70Genu varum (HP:0002970)2.20542258
71Mild short stature (HP:0003502)2.18043562
72Hypoglycemic coma (HP:0001325)2.16265566
73Deep philtrum (HP:0002002)2.15956490
74Tetraparesis (HP:0002273)2.15855507
75Prominent metopic ridge (HP:0005487)2.15212699
76Increased hepatocellular lipid droplets (HP:0006565)2.14482367
77Reduced antithrombin III activity (HP:0001976)2.14465127
78Abnormal foot bone ossification (HP:0010675)2.14319577
79Adrenal hypoplasia (HP:0000835)2.13684781
80Hypoplasia of the pons (HP:0012110)2.12114443
81Short tibia (HP:0005736)2.11747197
82Abnormality of the labia minora (HP:0012880)2.11014878
83Hypoplastic pelvis (HP:0008839)2.10190606
84Ectopic kidney (HP:0000086)2.09478222
85Abnormality of the duodenum (HP:0002246)2.09476911
86Pancreatic cysts (HP:0001737)2.06331036
87Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)2.05694693
88Abnormal lung lobation (HP:0002101)2.05551938
89Cervical subluxation (HP:0003308)2.05046139
90Cortical dysplasia (HP:0002539)2.04891252
91Delayed gross motor development (HP:0002194)2.04726634
92Abnormality of the vertebral endplates (HP:0005106)2.04117540
93Meckel diverticulum (HP:0002245)2.04098025
94Irregular vertebral endplates (HP:0003301)2.03113022
95Abnormality of midbrain morphology (HP:0002418)2.02917619
96Molar tooth sign on MRI (HP:0002419)2.02917619
97Aplastic anemia (HP:0001915)2.02847742
98Cystic hygroma (HP:0000476)2.02709581
99Absent eyebrow (HP:0002223)2.02672351
100Optic nerve coloboma (HP:0000588)2.01201668
101Facial cleft (HP:0002006)1.99889236
102Posterior subcapsular cataract (HP:0007787)1.99742162
103Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.99702814
104Stenosis of the external auditory canal (HP:0000402)1.99131135
105Abnormal mitochondria in muscle tissue (HP:0008316)1.97490269
106Hepatoblastoma (HP:0002884)1.95167124
107Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)1.93612412
108Megaloblastic anemia (HP:0001889)1.93310320
109Dyschromatopsia (HP:0007641)1.92747090
110Mitochondrial inheritance (HP:0001427)1.92454140
111Mesomelia (HP:0003027)1.92217800
112Proximal tubulopathy (HP:0000114)1.91371784
113Aplasia/Hypoplasia of the tibia (HP:0005772)1.91177039
114Preaxial hand polydactyly (HP:0001177)1.91176203
115Cupped ribs (HP:0000887)1.91152133
116Asymmetry of the thorax (HP:0001555)1.90776003
117Medial flaring of the eyebrow (HP:0010747)1.89640319
118Genital tract atresia (HP:0001827)1.89455263
119Gait imbalance (HP:0002141)1.89070673
120Abnormality of the ileum (HP:0001549)1.89036273
121Increased serum lactate (HP:0002151)1.88491045
122Sloping forehead (HP:0000340)1.86302243
123Neonatal respiratory distress (HP:0002643)1.86081443
124Abnormality of the phalanges of the 5th finger (HP:0004213)1.85772945
125Beaking of vertebral bodies (HP:0004568)1.85667777
126Abnormality of chromosome stability (HP:0003220)1.85583847
127Hypoplasia of the capital femoral epiphysis (HP:0003090)1.84416932
128Neoplasm of the tracheobronchial system (HP:0100552)1.84248451
129Patellar aplasia (HP:0006443)1.84085815
130Cutaneous melanoma (HP:0012056)1.83882045
131Stillbirth (HP:0003826)1.83173292
132Disproportionate short-trunk short stature (HP:0003521)1.82762216
133Hepatic necrosis (HP:0002605)1.82576572
134Poor head control (HP:0002421)1.81959925
135Aplasia/Hypoplasia of the uvula (HP:0010293)1.81899034
136Metaphyseal irregularity (HP:0003025)1.81875268
137Osteomalacia (HP:0002749)1.81812022
138Abnormality of serum amino acid levels (HP:0003112)1.81246696
139Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.79901417
140Abnormality of alanine metabolism (HP:0010916)1.79901417
141Hyperalaninemia (HP:0003348)1.79901417
142Abnormality of the fovea (HP:0000493)1.79110100
143Progressive inability to walk (HP:0002505)1.78261744
144Abnormal auditory evoked potentials (HP:0006958)1.77662204
145Vaginal atresia (HP:0000148)1.77025237
146Nephrogenic diabetes insipidus (HP:0009806)1.76856977
147Breast carcinoma (HP:0003002)1.75737834
148Submucous cleft hard palate (HP:0000176)1.75635890
149Fibular hypoplasia (HP:0003038)1.75380275
150Abnormality of the ischium (HP:0003174)1.75023529
151Tongue fasciculations (HP:0001308)1.74744211
152Congenital primary aphakia (HP:0007707)1.74260586
153Aplasia/Hypoplasia of the patella (HP:0006498)1.73453109
154Pancreatic islet-cell hyperplasia (HP:0004510)1.72500248
155Renal cortical cysts (HP:0000803)1.72359841
156Dandy-Walker malformation (HP:0001305)1.72264330
157Breast hypoplasia (HP:0003187)1.71773700
158Abnormality of vitamin B metabolism (HP:0004340)1.71621225
159Short middle phalanx of the 5th finger (HP:0004220)1.71611474
160Meningocele (HP:0002435)1.71449476
161Abnormality of the frontal sinuses (HP:0002687)1.71190701
162Flattened epiphyses (HP:0003071)1.71097053
163Abnormality of the vitamin B12 metabolism (HP:0004341)1.70084142
164Hepatocellular necrosis (HP:0001404)1.69416785
165Non-midline cleft lip (HP:0100335)1.69115156
166Pulmonic stenosis (HP:0001642)1.68637886
167Congenital, generalized hypertrichosis (HP:0004540)1.67189629
168Occipital encephalocele (HP:0002085)1.66417181
169Abnormality of the preputium (HP:0100587)1.66164183
170Spinal muscular atrophy (HP:0007269)1.65891725
171Curly hair (HP:0002212)1.65563367
172Metaphyseal dysplasia (HP:0100255)1.65507089

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIM285.17002425
2AKT33.54540388
3ERBB33.44486216
4CASK2.85466911
5ZAK2.85046747
6BMPR22.55463708
7STK38L2.52249409
8EIF2AK12.47769871
9MAP3K142.37402219
10CDK192.32810558
11SIK32.28493283
12EIF2AK32.25525092
13PLK42.19700018
14SRPK12.12307767
15PLK22.10790994
16BRSK22.10269276
17PLK32.06816332
18MKNK11.96844999
19MKNK21.95284231
20TSSK61.94692293
21PRPF4B1.91481725
22FRK1.86091553
23STK241.85977145
24SGK21.73481072
25NEK61.67842231
26PASK1.58030199
27YES11.56886207
28VRK11.55392069
29IRAK31.48264358
30IRAK41.46415867
31BCR1.43730762
32BUB11.39856289
33EIF2AK21.37600802
34TRPM71.35813337
35STK161.29348728
36NUAK11.27183124
37BMPR1B1.24247121
38TNIK1.21703194
39MAP3K31.20091793
40BRAF1.19995361
41PIM21.19359176
42CDK81.18906729
43BRSK11.16341646
44KSR11.12328808
45TAF11.11480023
46MST41.11459802
47CDC71.10100801
48INSRR1.09743217
49CCNB11.08964093
50MAP4K21.01533094
51MAPK131.01374278
52NEK91.00419653
53ACVR1B0.94515222
54STK390.92525395
55ERBB40.91541184
56PRKD30.91193009
57PINK10.90305859
58CSNK1G10.88522621
59SGK2230.88332621
60SGK4940.88332621
61TESK10.86450181
62WEE10.84447735
63TXK0.83981992
64SGK30.83932682
65RPS6KB10.83738481
66PAK40.83584778
67CSNK1A1L0.83052883
68LATS10.80684739
69PLK10.76666913
70CSNK1G30.74546279
71GRK10.74512667
72CSNK1G20.72018808
73MYLK0.71474210
74MAP2K70.70657305
75CHUK0.69226601
76TEC0.68135747
77MAP3K120.66305708
78NME10.66060689
79STK30.65906336
80TGFBR20.65654682
81ATR0.65129402
82PIK3CA0.64976436
83CLK10.62628276
84PIM10.62394797
85FGFR10.61970635
86PAK30.61300276
87OXSR10.61039286
88PBK0.60903013
89MINK10.60596786
90RPS6KC10.60460902
91RPS6KL10.60460902
92CHEK20.60394837
93IKBKB0.59010378
94LIMK10.57688931
95EPHA30.57654931
96ADRBK20.57440372
97RPS6KA20.56762104
98TGFBR10.56365740
99ARAF0.55266971
100RPS6KA60.53089926
101TAOK20.48700299
102CSNK2A10.48548728
103EPHA20.45497300
104MAP3K90.43975842
105ILK0.43225218
106RAF10.42801249
107MAP3K40.42208377
108NLK0.41864413
109ATM0.41489814
110CDK30.41222350
111TIE10.40895633
112CAMK2D0.40645712
113RPS6KA40.40601489
114CDK70.39578767
115AURKB0.39032629
116DDR20.38949405
117AURKA0.38052007
118NEK10.37113220
119BCKDK0.37005757
120IRAK10.36797075
121JAK30.36399535
122FER0.36269752
123CDC42BPA0.35573199
124PRKCE0.34069639
125DYRK20.33712977
126WNK30.33689199
127MUSK0.33061393
128PIK3CG0.32213878
129TTK0.32024513
130PDK20.31793355
131FLT30.31217432
132DAPK10.31034972
133STK40.30319398
134VRK20.29998852
135CAMK2A0.29925271
136CHEK10.27080785
137MAP3K50.26052686
138CDK180.25877458
139CDK60.25298091
140CSNK2A20.24482818
141GSK3A0.24166418
142CSNK1E0.23237887

Predicted pathways (KEGG)

RankGene SetZ-score
1Protein export_Homo sapiens_hsa030604.74702644
2Proteasome_Homo sapiens_hsa030503.24687229
3DNA replication_Homo sapiens_hsa030302.87518211
4RNA polymerase_Homo sapiens_hsa030202.86133839
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.72572669
6Mismatch repair_Homo sapiens_hsa034302.62681737
7Steroid biosynthesis_Homo sapiens_hsa001002.53493236
8Base excision repair_Homo sapiens_hsa034102.32247551
9Homologous recombination_Homo sapiens_hsa034402.26434854
10Basal transcription factors_Homo sapiens_hsa030222.12562250
11Non-homologous end-joining_Homo sapiens_hsa034502.03291476
12Nucleotide excision repair_Homo sapiens_hsa034202.02452184
13Propanoate metabolism_Homo sapiens_hsa006401.99131433
14Cell cycle_Homo sapiens_hsa041101.94874728
15Pyrimidine metabolism_Homo sapiens_hsa002401.91661402
16SNARE interactions in vesicular transport_Homo sapiens_hsa041301.88423681
17RNA transport_Homo sapiens_hsa030131.85060081
18Fanconi anemia pathway_Homo sapiens_hsa034601.84476567
19RNA degradation_Homo sapiens_hsa030181.83247055
20Vitamin B6 metabolism_Homo sapiens_hsa007501.78092946
21Pentose phosphate pathway_Homo sapiens_hsa000301.71271299
22Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.71177913
23Maturity onset diabetes of the young_Homo sapiens_hsa049501.67624269
24Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.65480624
25One carbon pool by folate_Homo sapiens_hsa006701.63106966
26Spliceosome_Homo sapiens_hsa030401.61381835
27Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.59185884
28Vibrio cholerae infection_Homo sapiens_hsa051101.53753587
29Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.52760949
30Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.48218710
31Purine metabolism_Homo sapiens_hsa002301.44777894
32Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.35747295
33Fatty acid elongation_Homo sapiens_hsa000621.34885478
34Type I diabetes mellitus_Homo sapiens_hsa049401.34670195
35Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.34427409
36Cysteine and methionine metabolism_Homo sapiens_hsa002701.30313345
37Legionellosis_Homo sapiens_hsa051341.29000344
38N-Glycan biosynthesis_Homo sapiens_hsa005101.28205633
39Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.27074627
40Arachidonic acid metabolism_Homo sapiens_hsa005901.19584353
41Thyroid cancer_Homo sapiens_hsa052161.10831201
42Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.09344172
43p53 signaling pathway_Homo sapiens_hsa041151.08165114
44Glutathione metabolism_Homo sapiens_hsa004801.06453260
45Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.05962670
46Epstein-Barr virus infection_Homo sapiens_hsa051691.03877562
47Phagosome_Homo sapiens_hsa041451.02960044
48Biosynthesis of amino acids_Homo sapiens_hsa012301.02319056
49Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.97620190
50Folate biosynthesis_Homo sapiens_hsa007900.96677519
51Galactose metabolism_Homo sapiens_hsa000520.96395498
52Rheumatoid arthritis_Homo sapiens_hsa053230.94288509
53Graft-versus-host disease_Homo sapiens_hsa053320.91584022
54Pyruvate metabolism_Homo sapiens_hsa006200.91269516
55Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.91235496
56mRNA surveillance pathway_Homo sapiens_hsa030150.90238553
57Allograft rejection_Homo sapiens_hsa053300.89719136
582-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.89635361
59Carbon metabolism_Homo sapiens_hsa012000.87279421
60Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.83429465
61Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.79348428
62Autoimmune thyroid disease_Homo sapiens_hsa053200.78195584
63Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.77554646
64Collecting duct acid secretion_Homo sapiens_hsa049660.73233322
65Antigen processing and presentation_Homo sapiens_hsa046120.71333755
66Herpes simplex infection_Homo sapiens_hsa051680.68605299
67Huntingtons disease_Homo sapiens_hsa050160.67252679
68Measles_Homo sapiens_hsa051620.66345803
69TGF-beta signaling pathway_Homo sapiens_hsa043500.66257358
70Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.64045842
71Sulfur metabolism_Homo sapiens_hsa009200.63424571
72Oxidative phosphorylation_Homo sapiens_hsa001900.61667751
73Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.60640785
74Pentose and glucuronate interconversions_Homo sapiens_hsa000400.60573262
75NF-kappa B signaling pathway_Homo sapiens_hsa040640.60391399
76Metabolic pathways_Homo sapiens_hsa011000.60317936
77Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.57570091
78Prostate cancer_Homo sapiens_hsa052150.57226029
79Sphingolipid metabolism_Homo sapiens_hsa006000.56371552
80Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.51316947
81Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.51309154
82Primary bile acid biosynthesis_Homo sapiens_hsa001200.50887253
83Viral carcinogenesis_Homo sapiens_hsa052030.50777215
84Other glycan degradation_Homo sapiens_hsa005110.50647816
85Influenza A_Homo sapiens_hsa051640.50381740
86Alzheimers disease_Homo sapiens_hsa050100.50328359
87HTLV-I infection_Homo sapiens_hsa051660.50301709
88PI3K-Akt signaling pathway_Homo sapiens_hsa041510.49907855
89NOD-like receptor signaling pathway_Homo sapiens_hsa046210.49350617
90Regulation of autophagy_Homo sapiens_hsa041400.48248803
91Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.47433654
92Melanoma_Homo sapiens_hsa052180.47337030
93Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.46663184
94Parkinsons disease_Homo sapiens_hsa050120.45130731
95Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.44868595
96RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.42220468
97ECM-receptor interaction_Homo sapiens_hsa045120.41534096
98Peroxisome_Homo sapiens_hsa041460.41239545
99Butanoate metabolism_Homo sapiens_hsa006500.40207793
100Fructose and mannose metabolism_Homo sapiens_hsa000510.39254135
101Hepatitis B_Homo sapiens_hsa051610.38625922
102Asthma_Homo sapiens_hsa053100.37779209
103Intestinal immune network for IgA production_Homo sapiens_hsa046720.37530035
104Hematopoietic cell lineage_Homo sapiens_hsa046400.37312566
105Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.37161922
106Phototransduction_Homo sapiens_hsa047440.36817671
107Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.36251784
108Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.36024123
109Malaria_Homo sapiens_hsa051440.35726621
110Hippo signaling pathway_Homo sapiens_hsa043900.34697688
111Oocyte meiosis_Homo sapiens_hsa041140.33939551
112Adherens junction_Homo sapiens_hsa045200.33784368
113Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.33371382
114Selenocompound metabolism_Homo sapiens_hsa004500.33261257
115Fatty acid metabolism_Homo sapiens_hsa012120.31369160
116Apoptosis_Homo sapiens_hsa042100.31167806
117Circadian rhythm_Homo sapiens_hsa047100.30944085
118Protein digestion and absorption_Homo sapiens_hsa049740.30261630
119Hedgehog signaling pathway_Homo sapiens_hsa043400.30018456
120Transcriptional misregulation in cancer_Homo sapiens_hsa052020.29977748
121Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.29947059
122Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.28692545
123Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.28463472
124Arginine and proline metabolism_Homo sapiens_hsa003300.28297669
125Drug metabolism - other enzymes_Homo sapiens_hsa009830.28205997
126Shigellosis_Homo sapiens_hsa051310.27538178
127FoxO signaling pathway_Homo sapiens_hsa040680.27451917
128Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.26426025
129Leishmaniasis_Homo sapiens_hsa051400.26379794
130Olfactory transduction_Homo sapiens_hsa047400.25230771
131Endometrial cancer_Homo sapiens_hsa052130.24917987
132MicroRNAs in cancer_Homo sapiens_hsa052060.23821371
133TNF signaling pathway_Homo sapiens_hsa046680.22271036
134Mineral absorption_Homo sapiens_hsa049780.21668385
135Insulin secretion_Homo sapiens_hsa049110.21614755
136Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.20494910
137Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.19381581
138Vitamin digestion and absorption_Homo sapiens_hsa049770.15292878
139Caffeine metabolism_Homo sapiens_hsa002320.13824042
140beta-Alanine metabolism_Homo sapiens_hsa004100.13364254
141Nitrogen metabolism_Homo sapiens_hsa009100.13354840

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