

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of memory T cell differentiation (GO:0043380) | 5.16989405 |
| 2 | regulation of activation of Janus kinase activity (GO:0010533) | 4.85324963 |
| 3 | negative regulation of cell killing (GO:0031342) | 4.74889209 |
| 4 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.74889209 |
| 5 | DNA deamination (GO:0045006) | 4.68906394 |
| 6 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 4.54598675 |
| 7 | protein polyglutamylation (GO:0018095) | 4.29927478 |
| 8 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 4.21509397 |
| 9 | regulation of mitotic spindle checkpoint (GO:1903504) | 4.21509397 |
| 10 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 4.20590910 |
| 11 | protein-cofactor linkage (GO:0018065) | 4.12734468 |
| 12 | base-excision repair, AP site formation (GO:0006285) | 4.11637409 |
| 13 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 4.08842251 |
| 14 | kynurenine metabolic process (GO:0070189) | 4.03489180 |
| 15 | positive regulation of defense response to virus by host (GO:0002230) | 3.96612595 |
| 16 | S-adenosylmethionine metabolic process (GO:0046500) | 3.83965170 |
| 17 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 3.77737320 |
| 18 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.70251635 |
| 19 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.70251635 |
| 20 | isotype switching (GO:0045190) | 3.59612008 |
| 21 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.59612008 |
| 22 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.59612008 |
| 23 | protein deneddylation (GO:0000338) | 3.55415108 |
| 24 | iron-sulfur cluster assembly (GO:0016226) | 3.48772073 |
| 25 | metallo-sulfur cluster assembly (GO:0031163) | 3.48772073 |
| 26 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.46273572 |
| 27 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.44745294 |
| 28 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.44745294 |
| 29 | rRNA catabolic process (GO:0016075) | 3.42027452 |
| 30 | positive regulation of T-helper 1 type immune response (GO:0002827) | 3.37528941 |
| 31 | ubiquinone metabolic process (GO:0006743) | 3.35817054 |
| 32 | positive regulation of interleukin-17 production (GO:0032740) | 3.35599728 |
| 33 | cellular response to nicotine (GO:0071316) | 3.33417045 |
| 34 | ubiquinone biosynthetic process (GO:0006744) | 3.30771883 |
| 35 | aspartate family amino acid biosynthetic process (GO:0009067) | 3.29569479 |
| 36 | negative regulation of interleukin-10 production (GO:0032693) | 3.29371195 |
| 37 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.21882587 |
| 38 | retinal cone cell development (GO:0046549) | 3.21627577 |
| 39 | positive regulation of prostaglandin secretion (GO:0032308) | 3.20645435 |
| 40 | DNA damage response, detection of DNA damage (GO:0042769) | 3.18482192 |
| 41 | positive regulation of osteoclast differentiation (GO:0045672) | 3.13337793 |
| 42 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.12639393 |
| 43 | amino acid salvage (GO:0043102) | 3.12217869 |
| 44 | L-methionine salvage (GO:0071267) | 3.12217869 |
| 45 | L-methionine biosynthetic process (GO:0071265) | 3.12217869 |
| 46 | fucose catabolic process (GO:0019317) | 3.11974701 |
| 47 | L-fucose metabolic process (GO:0042354) | 3.11974701 |
| 48 | L-fucose catabolic process (GO:0042355) | 3.11974701 |
| 49 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.09338064 |
| 50 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.07342275 |
| 51 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 3.06877072 |
| 52 | branched-chain amino acid catabolic process (GO:0009083) | 3.06793187 |
| 53 | positive regulation of cell fate commitment (GO:0010455) | 3.04589250 |
| 54 | somatic diversification of immunoglobulins (GO:0016445) | 3.04300554 |
| 55 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.02806406 |
| 56 | negative regulation of neurological system process (GO:0031645) | 3.00731773 |
| 57 | sleep (GO:0030431) | 2.96490084 |
| 58 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.96019721 |
| 59 | protein complex biogenesis (GO:0070271) | 2.94643603 |
| 60 | regulation of germinal center formation (GO:0002634) | 2.93967029 |
| 61 | dicarboxylic acid catabolic process (GO:0043649) | 2.93586783 |
| 62 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.91292152 |
| 63 | purine deoxyribonucleotide metabolic process (GO:0009151) | 2.90881781 |
| 64 | somatic recombination of immunoglobulin gene segments (GO:0016447) | 2.89601243 |
| 65 | regulation of defense response to virus by host (GO:0050691) | 2.88785762 |
| 66 | aspartate family amino acid catabolic process (GO:0009068) | 2.87395989 |
| 67 | deoxyribose phosphate metabolic process (GO:0019692) | 2.84066259 |
| 68 | protein localization to cilium (GO:0061512) | 2.82970348 |
| 69 | ADP metabolic process (GO:0046031) | 2.82368426 |
| 70 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.81399653 |
| 71 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.80780762 |
| 72 | 2-deoxyribonucleotide metabolic process (GO:0009394) | 2.80345434 |
| 73 | positive regulation of mitochondrial fission (GO:0090141) | 2.79847729 |
| 74 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.79053102 |
| 75 | regulation of T-helper 1 type immune response (GO:0002825) | 2.78720279 |
| 76 | cullin deneddylation (GO:0010388) | 2.77482810 |
| 77 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.77409377 |
| 78 | histone H2A ubiquitination (GO:0033522) | 2.77247623 |
| 79 | negative regulation of T cell apoptotic process (GO:0070233) | 2.77108547 |
| 80 | deoxyribonucleoside diphosphate metabolic process (GO:0009186) | 2.76885031 |
| 81 | regulation of cilium movement (GO:0003352) | 2.72856356 |
| 82 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.72814837 |
| 83 | cellular response to interleukin-15 (GO:0071350) | 2.71817115 |
| 84 | positive regulation of oligodendrocyte differentiation (GO:0048714) | 2.71439145 |
| 85 | mitochondrial RNA metabolic process (GO:0000959) | 2.68513765 |
| 86 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.67377622 |
| 87 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2.65356215 |
| 88 | postreplication repair (GO:0006301) | 2.64550273 |
| 89 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.63192055 |
| 90 | termination of RNA polymerase III transcription (GO:0006386) | 2.63192055 |
| 91 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.62839965 |
| 92 | adenosine metabolic process (GO:0046085) | 2.62410803 |
| 93 | regulation of translational termination (GO:0006449) | 2.61040051 |
| 94 | protein K6-linked ubiquitination (GO:0085020) | 2.60555365 |
| 95 | histone H2A monoubiquitination (GO:0035518) | 2.60520707 |
| 96 | methionine biosynthetic process (GO:0009086) | 2.59752914 |
| 97 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.58404446 |
| 98 | retinal rod cell development (GO:0046548) | 2.57573384 |
| 99 | molting cycle (GO:0042303) | 2.56675985 |
| 100 | hair cycle (GO:0042633) | 2.56675985 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.52841978 |
| 2 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.96108473 |
| 3 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.93248827 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.74171487 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.48876594 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.42316913 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.00508640 |
| 8 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.95727173 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.78504821 |
| 10 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.76598055 |
| 11 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.66479632 |
| 12 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.56939102 |
| 13 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.54980399 |
| 14 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.50615271 |
| 15 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.48800879 |
| 16 | IRF1_19129219_ChIP-ChIP_H3396_Human | 2.42017505 |
| 17 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.21970277 |
| 18 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.19199064 |
| 19 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.19192330 |
| 20 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.18758155 |
| 21 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.16338425 |
| 22 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.10964909 |
| 23 | MYC_18940864_ChIP-ChIP_HL60_Human | 2.02317294 |
| 24 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.00882394 |
| 25 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.96754088 |
| 26 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.95149157 |
| 27 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.87811949 |
| 28 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.87393368 |
| 29 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.85402874 |
| 30 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.84935004 |
| 31 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.77699549 |
| 32 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.77157232 |
| 33 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.76763009 |
| 34 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.75688198 |
| 35 | VDR_22108803_ChIP-Seq_LS180_Human | 1.68658311 |
| 36 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.68053024 |
| 37 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.66519300 |
| 38 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.63789692 |
| 39 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.53491841 |
| 40 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.51000371 |
| 41 | GATA3_26560356_Chip-Seq_TH2_Human | 1.48879254 |
| 42 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.48585751 |
| 43 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.46700149 |
| 44 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.46633302 |
| 45 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.44667008 |
| 46 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.42560753 |
| 47 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.40167780 |
| 48 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.39976624 |
| 49 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.35219132 |
| 50 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.34781305 |
| 51 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.33177545 |
| 52 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.32712126 |
| 53 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.31495010 |
| 54 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.29664013 |
| 55 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.29521128 |
| 56 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.29217681 |
| 57 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.28883966 |
| 58 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.27701234 |
| 59 | MYB_26560356_Chip-Seq_TH2_Human | 1.25479292 |
| 60 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.25335033 |
| 61 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.23119422 |
| 62 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.22377682 |
| 63 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.20476612 |
| 64 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.18840918 |
| 65 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.16510835 |
| 66 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.12940310 |
| 67 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.09688999 |
| 68 | EWS_26573619_Chip-Seq_HEK293_Human | 1.08575553 |
| 69 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.08208501 |
| 70 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.07845946 |
| 71 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.06941146 |
| 72 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.05906531 |
| 73 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.05738864 |
| 74 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03854413 |
| 75 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.03819803 |
| 76 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.96383511 |
| 77 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.96383511 |
| 78 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.95638312 |
| 79 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.94892995 |
| 80 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.94544438 |
| 81 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.93720612 |
| 82 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.93133059 |
| 83 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.92598102 |
| 84 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.92598102 |
| 85 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.92542658 |
| 86 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.90351824 |
| 87 | GATA3_26560356_Chip-Seq_TH1_Human | 0.87264675 |
| 88 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.87165013 |
| 89 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.86746026 |
| 90 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.86399878 |
| 91 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 0.85469824 |
| 92 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.85356211 |
| 93 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.85241829 |
| 94 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.84754466 |
| 95 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.84515695 |
| 96 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.84216925 |
| 97 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.83924046 |
| 98 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 0.81080351 |
| 99 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.78410396 |
| 100 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.78192344 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002102_abnormal_ear_morphology | 4.04534967 |
| 2 | MP0008877_abnormal_DNA_methylation | 3.99449507 |
| 3 | MP0005075_abnormal_melanosome_morpholog | 3.90429135 |
| 4 | MP0005671_abnormal_response_to | 3.40556842 |
| 5 | MP0006072_abnormal_retinal_apoptosis | 3.29532529 |
| 6 | MP0003787_abnormal_imprinting | 3.11832874 |
| 7 | MP0001529_abnormal_vocalization | 2.79698906 |
| 8 | MP0003786_premature_aging | 2.30608405 |
| 9 | MP0003724_increased_susceptibility_to | 2.30362017 |
| 10 | MP0005645_abnormal_hypothalamus_physiol | 2.20745172 |
| 11 | MP0010094_abnormal_chromosome_stability | 2.13387798 |
| 12 | MP0003763_abnormal_thymus_physiology | 2.12905428 |
| 13 | MP0008058_abnormal_DNA_repair | 2.07103413 |
| 14 | MP0005646_abnormal_pituitary_gland | 1.90150188 |
| 15 | MP0003646_muscle_fatigue | 1.84564336 |
| 16 | MP0003693_abnormal_embryo_hatching | 1.80732163 |
| 17 | MP0005084_abnormal_gallbladder_morpholo | 1.80556128 |
| 18 | MP0003195_calcinosis | 1.80395949 |
| 19 | MP0005000_abnormal_immune_tolerance | 1.76880528 |
| 20 | MP0005377_hearing/vestibular/ear_phenot | 1.72964874 |
| 21 | MP0003878_abnormal_ear_physiology | 1.72964874 |
| 22 | MP0005253_abnormal_eye_physiology | 1.64235791 |
| 23 | MP0008872_abnormal_physiological_respon | 1.62601428 |
| 24 | MP0001984_abnormal_olfaction | 1.62503579 |
| 25 | MP0008789_abnormal_olfactory_epithelium | 1.57949058 |
| 26 | MP0006276_abnormal_autonomic_nervous | 1.54509373 |
| 27 | MP0001835_abnormal_antigen_presentation | 1.49008689 |
| 28 | MP0001919_abnormal_reproductive_system | 1.42110877 |
| 29 | MP0002166_altered_tumor_susceptibility | 1.39939067 |
| 30 | MP0002638_abnormal_pupillary_reflex | 1.38234944 |
| 31 | MP0005551_abnormal_eye_electrophysiolog | 1.36145896 |
| 32 | MP0003121_genomic_imprinting | 1.34946727 |
| 33 | MP0001188_hyperpigmentation | 1.34207386 |
| 34 | MP0002234_abnormal_pharynx_morphology | 1.32515307 |
| 35 | MP0002254_reproductive_system_inflammat | 1.30196594 |
| 36 | MP0001968_abnormal_touch/_nociception | 1.28858697 |
| 37 | MP0002736_abnormal_nociception_after | 1.28848394 |
| 38 | MP0002723_abnormal_immune_serum | 1.27502175 |
| 39 | MP0002822_catalepsy | 1.27453665 |
| 40 | MP0002163_abnormal_gland_morphology | 1.26232827 |
| 41 | MP0001501_abnormal_sleep_pattern | 1.25003040 |
| 42 | MP0005499_abnormal_olfactory_system | 1.24433715 |
| 43 | MP0005394_taste/olfaction_phenotype | 1.24433715 |
| 44 | MP0008875_abnormal_xenobiotic_pharmacok | 1.16503247 |
| 45 | MP0002148_abnormal_hypersensitivity_rea | 1.16476359 |
| 46 | MP0001764_abnormal_homeostasis | 1.15437417 |
| 47 | MP0001800_abnormal_humoral_immune | 1.15202929 |
| 48 | MP0003111_abnormal_nucleus_morphology | 1.15165506 |
| 49 | MP0006035_abnormal_mitochondrial_morpho | 1.14135996 |
| 50 | MP0002272_abnormal_nervous_system | 1.13397396 |
| 51 | MP0003436_decreased_susceptibility_to | 1.10594408 |
| 52 | MP0001819_abnormal_immune_cell | 1.09681715 |
| 53 | MP0000372_irregular_coat_pigmentation | 1.07657514 |
| 54 | MP0002006_tumorigenesis | 1.06423607 |
| 55 | MP0002420_abnormal_adaptive_immunity | 1.05533679 |
| 56 | MP0000689_abnormal_spleen_morphology | 1.03136635 |
| 57 | MP0005310_abnormal_salivary_gland | 1.01745086 |
| 58 | MP0004147_increased_porphyrin_level | 1.01582333 |
| 59 | MP0008775_abnormal_heart_ventricle | 1.01492246 |
| 60 | MP0002722_abnormal_immune_system | 1.00980767 |
| 61 | MP0009333_abnormal_splenocyte_physiolog | 1.00687703 |
| 62 | MP0008995_early_reproductive_senescence | 0.97563698 |
| 63 | MP0008932_abnormal_embryonic_tissue | 0.97162670 |
| 64 | MP0004924_abnormal_behavior | 0.95878185 |
| 65 | MP0005386_behavior/neurological_phenoty | 0.95878185 |
| 66 | MP0004885_abnormal_endolymph | 0.95502643 |
| 67 | MP0002398_abnormal_bone_marrow | 0.94198962 |
| 68 | MP0002452_abnormal_antigen_presenting | 0.94087572 |
| 69 | MP0003866_abnormal_defecation | 0.93529756 |
| 70 | MP0002751_abnormal_autonomic_nervous | 0.93130709 |
| 71 | MP0000703_abnormal_thymus_morphology | 0.90652211 |
| 72 | MP0002876_abnormal_thyroid_physiology | 0.90455289 |
| 73 | MP0003638_abnormal_response/metabolism_ | 0.89691407 |
| 74 | MP0009785_altered_susceptibility_to | 0.89615753 |
| 75 | MP0000716_abnormal_immune_system | 0.88737150 |
| 76 | MP0009046_muscle_twitch | 0.88204413 |
| 77 | MP0004215_abnormal_myocardial_fiber | 0.88157965 |
| 78 | MP0005389_reproductive_system_phenotype | 0.87917924 |
| 79 | MP0002933_joint_inflammation | 0.87838311 |
| 80 | MP0004142_abnormal_muscle_tone | 0.84253086 |
| 81 | MP0006036_abnormal_mitochondrial_physio | 0.83971241 |
| 82 | MP0002009_preneoplasia | 0.83800390 |
| 83 | MP0005647_abnormal_sex_gland | 0.83198854 |
| 84 | MP0009764_decreased_sensitivity_to | 0.81961885 |
| 85 | MP0005387_immune_system_phenotype | 0.80947083 |
| 86 | MP0001790_abnormal_immune_system | 0.80947083 |
| 87 | MP0010368_abnormal_lymphatic_system | 0.80362085 |
| 88 | MP0003045_fibrosis | 0.79365455 |
| 89 | MP0001661_extended_life_span | 0.79058852 |
| 90 | MP0000685_abnormal_immune_system | 0.78943883 |
| 91 | MP0000647_abnormal_sebaceous_gland | 0.78927866 |
| 92 | MP0003806_abnormal_nucleotide_metabolis | 0.78075988 |
| 93 | MP0003122_maternal_imprinting | 0.77927940 |
| 94 | MP0005025_abnormal_response_to | 0.75613400 |
| 95 | MP0000465_gastrointestinal_hemorrhage | 0.74410128 |
| 96 | MP0008007_abnormal_cellular_replicative | 0.73942166 |
| 97 | MP0003011_delayed_dark_adaptation | 0.70281437 |
| 98 | MP0003567_abnormal_fetal_cardiomyocyte | 0.69957916 |
| 99 | MP0002405_respiratory_system_inflammati | 0.69366962 |
| 100 | MP0001845_abnormal_inflammatory_respons | 0.67496064 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IgG deficiency (HP:0004315) | 4.15396809 |
| 2 | Retrobulbar optic neuritis (HP:0100654) | 3.73575086 |
| 3 | Optic neuritis (HP:0100653) | 3.73575086 |
| 4 | Visual hallucinations (HP:0002367) | 3.71004010 |
| 5 | Adactyly (HP:0009776) | 3.62767914 |
| 6 | Renal cortical cysts (HP:0000803) | 3.62485573 |
| 7 | Amyotrophic lateral sclerosis (HP:0007354) | 3.56035750 |
| 8 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.40926891 |
| 9 | Mitochondrial inheritance (HP:0001427) | 3.33885144 |
| 10 | Hepatocellular necrosis (HP:0001404) | 3.29555850 |
| 11 | Increased CSF lactate (HP:0002490) | 3.24478617 |
| 12 | Acute necrotizing encephalopathy (HP:0006965) | 3.14438918 |
| 13 | Myositis (HP:0100614) | 3.08981195 |
| 14 | Increased intramyocellular lipid droplets (HP:0012240) | 3.04707082 |
| 15 | Attenuation of retinal blood vessels (HP:0007843) | 2.98146223 |
| 16 | Orchitis (HP:0100796) | 2.91378377 |
| 17 | Keratoconjunctivitis (HP:0001096) | 2.91131492 |
| 18 | Increased muscle lipid content (HP:0009058) | 2.90242218 |
| 19 | Abnormality of eosinophils (HP:0001879) | 2.89307082 |
| 20 | Hepatic necrosis (HP:0002605) | 2.87987901 |
| 21 | Congenital stationary night blindness (HP:0007642) | 2.71725654 |
| 22 | Increased serum lactate (HP:0002151) | 2.71488206 |
| 23 | Lipid accumulation in hepatocytes (HP:0006561) | 2.70964824 |
| 24 | Severe combined immunodeficiency (HP:0004430) | 2.69198232 |
| 25 | Abolished electroretinogram (ERG) (HP:0000550) | 2.68058503 |
| 26 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.63299155 |
| 27 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.63299155 |
| 28 | Acute encephalopathy (HP:0006846) | 2.57264947 |
| 29 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 2.56143778 |
| 30 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.56034169 |
| 31 | Distal arthrogryposis (HP:0005684) | 2.54713825 |
| 32 | Prostate neoplasm (HP:0100787) | 2.52497715 |
| 33 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 2.50300844 |
| 34 | Brittle hair (HP:0002299) | 2.48483087 |
| 35 | Keratoconjunctivitis sicca (HP:0001097) | 2.47901474 |
| 36 | Progressive macrocephaly (HP:0004481) | 2.41952877 |
| 37 | Lactic acidosis (HP:0003128) | 2.41242012 |
| 38 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.37305228 |
| 39 | Increased hepatocellular lipid droplets (HP:0006565) | 2.36476755 |
| 40 | Peripheral hypomyelination (HP:0007182) | 2.35004575 |
| 41 | Premature loss of primary teeth (HP:0006323) | 2.31882215 |
| 42 | Progressive microcephaly (HP:0000253) | 2.27908928 |
| 43 | Abnormality of the prostate (HP:0008775) | 2.27830273 |
| 44 | Broad alveolar ridges (HP:0000187) | 2.27511616 |
| 45 | Progressive inability to walk (HP:0002505) | 2.25989754 |
| 46 | Abnormality of the renal cortex (HP:0011035) | 2.25988869 |
| 47 | Nephronophthisis (HP:0000090) | 2.25976637 |
| 48 | Eosinophilia (HP:0001880) | 2.25397456 |
| 49 | Abnormality of T cell number (HP:0011839) | 2.23831167 |
| 50 | Hypoplasia of the pons (HP:0012110) | 2.22185154 |
| 51 | Abnormality of macular pigmentation (HP:0008002) | 2.17357281 |
| 52 | Pachygyria (HP:0001302) | 2.16677325 |
| 53 | Keratitis (HP:0000491) | 2.16589528 |
| 54 | Cerebral edema (HP:0002181) | 2.15992866 |
| 55 | T lymphocytopenia (HP:0005403) | 2.14680351 |
| 56 | Combined immunodeficiency (HP:0005387) | 2.14625309 |
| 57 | Abnormality of the pons (HP:0007361) | 2.13202351 |
| 58 | Abnormality of the alveolar ridges (HP:0006477) | 2.11175126 |
| 59 | Optic disc pallor (HP:0000543) | 2.10923863 |
| 60 | Medial flaring of the eyebrow (HP:0010747) | 2.10095324 |
| 61 | Renal Fanconi syndrome (HP:0001994) | 2.00485056 |
| 62 | Abnormality of dental color (HP:0011073) | 1.99622737 |
| 63 | Inability to walk (HP:0002540) | 1.98895368 |
| 64 | Erythroderma (HP:0001019) | 1.98709243 |
| 65 | Absent thumb (HP:0009777) | 1.97837604 |
| 66 | Abnormality of the labia minora (HP:0012880) | 1.94339739 |
| 67 | Failure to thrive in infancy (HP:0001531) | 1.92330305 |
| 68 | Type II lissencephaly (HP:0007260) | 1.91736073 |
| 69 | Hypoproteinemia (HP:0003075) | 1.89465074 |
| 70 | Methylmalonic aciduria (HP:0012120) | 1.88328832 |
| 71 | Granulocytopenia (HP:0001913) | 1.87823496 |
| 72 | 3-Methylglutaconic aciduria (HP:0003535) | 1.86617312 |
| 73 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 1.86385542 |
| 74 | Sclerocornea (HP:0000647) | 1.85519628 |
| 75 | Lissencephaly (HP:0001339) | 1.84169143 |
| 76 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.83395965 |
| 77 | Polyphagia (HP:0002591) | 1.82987024 |
| 78 | Stomach cancer (HP:0012126) | 1.81806384 |
| 79 | Respiratory failure (HP:0002878) | 1.80391652 |
| 80 | Methylmalonic acidemia (HP:0002912) | 1.79225616 |
| 81 | Dialeptic seizures (HP:0011146) | 1.78942834 |
| 82 | Ependymoma (HP:0002888) | 1.78096777 |
| 83 | Pancreatic cysts (HP:0001737) | 1.76300931 |
| 84 | Sparse eyelashes (HP:0000653) | 1.76230364 |
| 85 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.76058390 |
| 86 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.75931210 |
| 87 | Opisthotonus (HP:0002179) | 1.75814174 |
| 88 | Pendular nystagmus (HP:0012043) | 1.75483959 |
| 89 | Abnormality of alanine metabolism (HP:0010916) | 1.74017241 |
| 90 | Hyperalaninemia (HP:0003348) | 1.74017241 |
| 91 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.74017241 |
| 92 | Nephrogenic diabetes insipidus (HP:0009806) | 1.73121236 |
| 93 | Abnormality of the renal medulla (HP:0100957) | 1.70452239 |
| 94 | Pancytopenia (HP:0001876) | 1.68967879 |
| 95 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.68863414 |
| 96 | Exercise intolerance (HP:0003546) | 1.68207285 |
| 97 | Chromsome breakage (HP:0040012) | 1.68138509 |
| 98 | Encephalitis (HP:0002383) | 1.67802506 |
| 99 | Duplicated collecting system (HP:0000081) | 1.67749887 |
| 100 | CNS demyelination (HP:0007305) | 1.67513216 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K2 | 4.17518316 |
| 2 | TESK2 | 3.45017474 |
| 3 | TAOK3 | 3.27228425 |
| 4 | TXK | 3.05459383 |
| 5 | MAP2K2 | 2.82306629 |
| 6 | NUAK1 | 2.60452102 |
| 7 | BCKDK | 2.48543481 |
| 8 | TLK1 | 2.36217571 |
| 9 | TRIM28 | 2.33079183 |
| 10 | KDR | 2.23547520 |
| 11 | BUB1 | 2.18660289 |
| 12 | BCR | 2.08833707 |
| 13 | SIK3 | 2.03504392 |
| 14 | MAP3K14 | 1.96722308 |
| 15 | VRK2 | 1.95139796 |
| 16 | ACVR1B | 1.88995660 |
| 17 | ZAK | 1.88267617 |
| 18 | MUSK | 1.80119168 |
| 19 | ERBB3 | 1.75816736 |
| 20 | CSNK1G2 | 1.73582075 |
| 21 | MATK | 1.64175706 |
| 22 | EPHA3 | 1.61698694 |
| 23 | MAP3K4 | 1.56109412 |
| 24 | GRK6 | 1.46697528 |
| 25 | SRPK1 | 1.45489210 |
| 26 | GRK1 | 1.42829650 |
| 27 | CSNK1G3 | 1.39176560 |
| 28 | VRK1 | 1.34276501 |
| 29 | WNK3 | 1.33548386 |
| 30 | CSNK1A1L | 1.32457423 |
| 31 | MAP4K1 | 1.30208923 |
| 32 | ADRBK2 | 1.28074854 |
| 33 | RPS6KA4 | 1.21972664 |
| 34 | ARAF | 1.18174273 |
| 35 | OXSR1 | 1.17086434 |
| 36 | TSSK6 | 1.14515969 |
| 37 | LIMK1 | 1.10880231 |
| 38 | IKBKB | 1.04542183 |
| 39 | FES | 1.04494302 |
| 40 | CSNK1G1 | 1.00713065 |
| 41 | PLK4 | 1.00430742 |
| 42 | MAPK13 | 0.93878631 |
| 43 | PLK3 | 0.87816757 |
| 44 | CDC7 | 0.85176648 |
| 45 | IRAK4 | 0.85007451 |
| 46 | BMPR2 | 0.84885852 |
| 47 | PRKCQ | 0.84480227 |
| 48 | MAPKAPK3 | 0.84090568 |
| 49 | INSRR | 0.82997859 |
| 50 | WNK4 | 0.78967326 |
| 51 | RPS6KA5 | 0.76092802 |
| 52 | STK16 | 0.75348647 |
| 53 | DAPK1 | 0.75343404 |
| 54 | RAF1 | 0.72967790 |
| 55 | MST4 | 0.72221531 |
| 56 | MARK3 | 0.70527159 |
| 57 | STK39 | 0.68959772 |
| 58 | CDK19 | 0.67612624 |
| 59 | ATR | 0.65207838 |
| 60 | PAK6 | 0.64109177 |
| 61 | EPHA4 | 0.62310237 |
| 62 | CLK1 | 0.59493101 |
| 63 | KIT | 0.57168479 |
| 64 | ITK | 0.56637844 |
| 65 | CDK4 | 0.53513608 |
| 66 | TBK1 | 0.52187284 |
| 67 | MAP2K7 | 0.52182680 |
| 68 | PLK1 | 0.52030983 |
| 69 | PIM2 | 0.51745487 |
| 70 | LCK | 0.50863584 |
| 71 | PIM1 | 0.49750270 |
| 72 | IKBKE | 0.48484759 |
| 73 | MKNK1 | 0.45804923 |
| 74 | TIE1 | 0.44833124 |
| 75 | FRK | 0.43948109 |
| 76 | PRKCE | 0.43279790 |
| 77 | AURKB | 0.42084077 |
| 78 | BRD4 | 0.41965280 |
| 79 | CCNB1 | 0.41724739 |
| 80 | PLK2 | 0.41704930 |
| 81 | TTK | 0.40792856 |
| 82 | SYK | 0.40681392 |
| 83 | EIF2AK2 | 0.40491996 |
| 84 | AURKA | 0.39523585 |
| 85 | TEC | 0.38355242 |
| 86 | MKNK2 | 0.38240560 |
| 87 | MAP2K1 | 0.38175718 |
| 88 | EIF2AK3 | 0.37314487 |
| 89 | IGF1R | 0.36480754 |
| 90 | NEK1 | 0.35667068 |
| 91 | JAK1 | 0.34538573 |
| 92 | PHKG2 | 0.34058952 |
| 93 | PHKG1 | 0.34058952 |
| 94 | TESK1 | 0.33800809 |
| 95 | CDK3 | 0.33564757 |
| 96 | LYN | 0.33371138 |
| 97 | CSNK1A1 | 0.32752983 |
| 98 | PRKCI | 0.31713681 |
| 99 | STK38L | 0.29197343 |
| 100 | PINK1 | 0.29105121 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 4.95729566 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.62301105 |
| 3 | Mismatch repair_Homo sapiens_hsa03430 | 2.70643599 |
| 4 | RNA polymerase_Homo sapiens_hsa03020 | 2.38209078 |
| 5 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.25778423 |
| 6 | DNA replication_Homo sapiens_hsa03030 | 2.25605440 |
| 7 | Base excision repair_Homo sapiens_hsa03410 | 2.20202718 |
| 8 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.04175868 |
| 9 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.96526944 |
| 10 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.95106374 |
| 11 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.92228328 |
| 12 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.92082395 |
| 13 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.91006069 |
| 14 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.87774521 |
| 15 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.85396096 |
| 16 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.83017491 |
| 17 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.79058092 |
| 18 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.73765830 |
| 19 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.71716241 |
| 20 | Parkinsons disease_Homo sapiens_hsa05012 | 1.69889488 |
| 21 | Spliceosome_Homo sapiens_hsa03040 | 1.68031240 |
| 22 | Protein export_Homo sapiens_hsa03060 | 1.65623365 |
| 23 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.62509574 |
| 24 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.60848910 |
| 25 | Homologous recombination_Homo sapiens_hsa03440 | 1.58635628 |
| 26 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.55953110 |
| 27 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.52798041 |
| 28 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.51626387 |
| 29 | RNA degradation_Homo sapiens_hsa03018 | 1.47828866 |
| 30 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.46251233 |
| 31 | Basal transcription factors_Homo sapiens_hsa03022 | 1.44162748 |
| 32 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.42437141 |
| 33 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.40830798 |
| 34 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.38159651 |
| 35 | Phototransduction_Homo sapiens_hsa04744 | 1.36465237 |
| 36 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.33413994 |
| 37 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.22810533 |
| 38 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.22776036 |
| 39 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.08925494 |
| 40 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.08889778 |
| 41 | Purine metabolism_Homo sapiens_hsa00230 | 1.07172333 |
| 42 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.06842318 |
| 43 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.06699603 |
| 44 | Allograft rejection_Homo sapiens_hsa05330 | 1.05142961 |
| 45 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.02414428 |
| 46 | Alzheimers disease_Homo sapiens_hsa05010 | 1.00396002 |
| 47 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.95462804 |
| 48 | Huntingtons disease_Homo sapiens_hsa05016 | 0.93228970 |
| 49 | Peroxisome_Homo sapiens_hsa04146 | 0.90969743 |
| 50 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.85455708 |
| 51 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.84557644 |
| 52 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.84394273 |
| 53 | Shigellosis_Homo sapiens_hsa05131 | 0.81757015 |
| 54 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.80428776 |
| 55 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.79226583 |
| 56 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.76263915 |
| 57 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.74946874 |
| 58 | Asthma_Homo sapiens_hsa05310 | 0.73910563 |
| 59 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.73766036 |
| 60 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.73043179 |
| 61 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.72814743 |
| 62 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.72452530 |
| 63 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.71523696 |
| 64 | Nicotine addiction_Homo sapiens_hsa05033 | 0.70684525 |
| 65 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.69989784 |
| 66 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.68576781 |
| 67 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.68529292 |
| 68 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.68336840 |
| 69 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.67083564 |
| 70 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.66737644 |
| 71 | RNA transport_Homo sapiens_hsa03013 | 0.66122846 |
| 72 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.64895719 |
| 73 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.62739493 |
| 74 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.61166039 |
| 75 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.60767789 |
| 76 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.60047573 |
| 77 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.57341000 |
| 78 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.54357107 |
| 79 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.53064302 |
| 80 | Metabolic pathways_Homo sapiens_hsa01100 | 0.52410227 |
| 81 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.50739045 |
| 82 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.49976691 |
| 83 | Legionellosis_Homo sapiens_hsa05134 | 0.49886902 |
| 84 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.48164793 |
| 85 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.45827466 |
| 86 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.43814458 |
| 87 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.42134393 |
| 88 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.41363932 |
| 89 | Taste transduction_Homo sapiens_hsa04742 | 0.38041434 |
| 90 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.36577640 |
| 91 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.36112209 |
| 92 | Viral myocarditis_Homo sapiens_hsa05416 | 0.31938530 |
| 93 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.31396443 |
| 94 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.30769846 |
| 95 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.30568244 |
| 96 | Cell cycle_Homo sapiens_hsa04110 | 0.30496520 |
| 97 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.30392121 |
| 98 | Carbon metabolism_Homo sapiens_hsa01200 | 0.29327010 |
| 99 | GABAergic synapse_Homo sapiens_hsa04727 | 0.29132249 |
| 100 | Circadian rhythm_Homo sapiens_hsa04710 | 0.29034972 |

