GPATCH1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA damage response, detection of DNA damage (GO:0042769)4.37495076
2protein complex biogenesis (GO:0070271)3.81563700
3centriole replication (GO:0007099)3.75448957
4chaperone-mediated protein transport (GO:0072321)3.74556882
5neuron cell-cell adhesion (GO:0007158)3.74129772
6DNA deamination (GO:0045006)3.72271085
7proteasome assembly (GO:0043248)3.68603442
8mitochondrial respiratory chain complex assembly (GO:0033108)3.67632597
9replication fork processing (GO:0031297)3.66845466
10cytochrome complex assembly (GO:0017004)3.65232557
11deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.64066247
12axon ensheathment in central nervous system (GO:0032291)3.63020779
13central nervous system myelination (GO:0022010)3.63020779
14water-soluble vitamin biosynthetic process (GO:0042364)3.58640129
15regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.54287777
16tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.52511986
17RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.52511986
18viral mRNA export from host cell nucleus (GO:0046784)3.45995212
19mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.43924776
20protein localization to synapse (GO:0035418)3.43734436
21positive regulation of synapse maturation (GO:0090129)3.42662324
22G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.41068332
23protein-cofactor linkage (GO:0018065)3.41003641
24base-excision repair, AP site formation (GO:0006285)3.38728992
25protein K6-linked ubiquitination (GO:0085020)3.38722230
26regulation of mitochondrial translation (GO:0070129)3.32748854
27respiratory chain complex IV assembly (GO:0008535)3.30855894
28neurotransmitter-gated ion channel clustering (GO:0072578)3.27293653
29positive regulation of dendritic spine morphogenesis (GO:0061003)3.22043294
30transcription elongation from RNA polymerase III promoter (GO:0006385)3.21472343
31termination of RNA polymerase III transcription (GO:0006386)3.21472343
32positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.18792766
33regulation of DNA endoreduplication (GO:0032875)3.18242327
34protein deneddylation (GO:0000338)3.17392911
35recombinational repair (GO:0000725)3.15340832
36positive regulation of histone H3-K4 methylation (GO:0051571)3.15259090
37synaptic transmission, glutamatergic (GO:0035249)3.14907750
38GMP metabolic process (GO:0046037)3.13237970
39response to pheromone (GO:0019236)3.10847817
40glutamate receptor signaling pathway (GO:0007215)3.10429412
41negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.10232371
42cullin deneddylation (GO:0010388)3.09619159
43DNA unwinding involved in DNA replication (GO:0006268)3.09203927
44double-strand break repair via homologous recombination (GO:0000724)3.08933785
45regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.07170818
46regulation of mitotic spindle checkpoint (GO:1903504)3.07170818
47positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.06897852
48presynaptic membrane organization (GO:0097090)3.06828470
49postsynaptic membrane organization (GO:0001941)3.04959737
50neuron-neuron synaptic transmission (GO:0007270)3.04708153
512-deoxyribonucleotide biosynthetic process (GO:0009265)3.03756319
52deoxyribose phosphate biosynthetic process (GO:0046385)3.03756319
53protein neddylation (GO:0045116)3.02897184
54presynaptic membrane assembly (GO:0097105)3.02758825
55regulation of glutamate receptor signaling pathway (GO:1900449)3.00785726
56tRNA processing (GO:0008033)2.99012332
57behavioral fear response (GO:0001662)2.97914366
58behavioral defense response (GO:0002209)2.97914366
59dopamine transport (GO:0015872)2.97884601
60regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.97602071
61mannosylation (GO:0097502)2.96032019
62regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.95917308
63telomere maintenance via telomerase (GO:0007004)2.95892827
64ionotropic glutamate receptor signaling pathway (GO:0035235)2.95415423
65gamma-aminobutyric acid signaling pathway (GO:0007214)2.95313497
66regulation of catecholamine metabolic process (GO:0042069)2.93917090
67regulation of dopamine metabolic process (GO:0042053)2.93917090
68negative regulation of DNA-dependent DNA replication (GO:2000104)2.92189088
69maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.90661470
70neurotransmitter uptake (GO:0001504)2.90561142
71DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.90475260
72fear response (GO:0042596)2.89908975
73RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.89843008
74spliceosomal complex assembly (GO:0000245)2.88998074
75regulation of short-term neuronal synaptic plasticity (GO:0048172)2.88840232
76signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.88706343
77signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.88706343
78signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.88706343
79rRNA modification (GO:0000154)2.88355235
80pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.87189970
81regulation of synapse maturation (GO:0090128)2.86934018
82positive regulation of dendritic spine development (GO:0060999)2.86753042
83vocalization behavior (GO:0071625)2.86392320
84anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.86213546
85positive regulation of response to oxidative stress (GO:1902884)2.86089260
86positive regulation of cellular response to oxidative stress (GO:1900409)2.86089260
87attachment of spindle microtubules to kinetochore (GO:0008608)2.85797765
88preassembly of GPI anchor in ER membrane (GO:0016254)2.85562974
89regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.84871489
90negative regulation of protein localization to cell surface (GO:2000009)2.84186911
91intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.84099904
92signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.84099904
93positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.83902902
94deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.83503557
95DNA ligation (GO:0006266)2.82950931
96mitochondrial RNA metabolic process (GO:0000959)2.82805158
97energy coupled proton transport, down electrochemical gradient (GO:0015985)2.82423827
98ATP synthesis coupled proton transport (GO:0015986)2.82423827
99DNA demethylation (GO:0080111)2.81368548
100maturation of SSU-rRNA (GO:0030490)2.80965634
101respiratory electron transport chain (GO:0022904)2.80745759
102electron transport chain (GO:0022900)2.80571817
103kinetochore assembly (GO:0051382)2.79695786
104nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.78239905
105signal transduction involved in cell cycle checkpoint (GO:0072395)2.77861305
106long-term memory (GO:0007616)2.77582001
107kinetochore organization (GO:0051383)2.77525245
108exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.76739716
109chromatin remodeling at centromere (GO:0031055)2.75858782
110DNA catabolic process, exonucleolytic (GO:0000738)2.75433576
111DNA double-strand break processing (GO:0000729)2.75246841
112signal transduction involved in DNA integrity checkpoint (GO:0072401)2.74425237
113signal transduction involved in DNA damage checkpoint (GO:0072422)2.74425237
114mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.74196128
115mitochondrial respiratory chain complex I assembly (GO:0032981)2.74196128
116NADH dehydrogenase complex assembly (GO:0010257)2.74196128
117pseudouridine synthesis (GO:0001522)2.74044148
118nucleotide-excision repair, DNA gap filling (GO:0006297)2.74028345
119resolution of meiotic recombination intermediates (GO:0000712)2.73744482
120reciprocal DNA recombination (GO:0035825)2.73648475
121reciprocal meiotic recombination (GO:0007131)2.73648475
122DNA replication initiation (GO:0006270)2.73585537
123tRNA metabolic process (GO:0006399)2.72857258
124postreplication repair (GO:0006301)2.72537751
125transmission of nerve impulse (GO:0019226)2.72289316
126negative regulation of ligase activity (GO:0051352)2.71758495
127negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.71758495
128drinking behavior (GO:0042756)2.71313754
129short-term memory (GO:0007614)2.70121115
130somatic hypermutation of immunoglobulin genes (GO:0016446)2.69889878
131somatic diversification of immune receptors via somatic mutation (GO:0002566)2.69889878
132neuromuscular process controlling posture (GO:0050884)2.69838184
133deoxyribonucleotide biosynthetic process (GO:0009263)2.69173604
134maturation of 5.8S rRNA (GO:0000460)2.68987946
135spliceosomal snRNP assembly (GO:0000387)2.68658492
136metallo-sulfur cluster assembly (GO:0031163)2.67578526
137iron-sulfur cluster assembly (GO:0016226)2.67578526
138sequestering of actin monomers (GO:0042989)2.65412793
139histone mRNA metabolic process (GO:0008334)2.65219229
140platelet dense granule organization (GO:0060155)2.65195080
141establishment of integrated proviral latency (GO:0075713)2.65124198
142regulation of helicase activity (GO:0051095)2.65086381
143GPI anchor biosynthetic process (GO:0006506)2.65061894
144regulation of meiosis I (GO:0060631)2.64171195
145DNA strand elongation (GO:0022616)2.63739886
146establishment of protein localization to mitochondrial membrane (GO:0090151)2.63734571
147behavioral response to nicotine (GO:0035095)2.63277092
148mismatch repair (GO:0006298)2.62854996
149centriole assembly (GO:0098534)2.62415459
150DNA replication checkpoint (GO:0000076)2.62290183
151mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.61855898
152protein K11-linked ubiquitination (GO:0070979)2.60837492
153positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.60696071
154protein prenylation (GO:0018342)2.59605476
155prenylation (GO:0097354)2.59605476
156epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.59473944
157synaptic vesicle exocytosis (GO:0016079)2.58717014
158detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.57815477
159L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.55835816
160regulation of cellular amino acid metabolic process (GO:0006521)2.55390371
161CENP-A containing nucleosome assembly (GO:0034080)2.54422919
162DNA damage response, signal transduction by p53 class mediator (GO:0030330)2.53338888
163cerebellum development (GO:0021549)2.53164125
164retinal rod cell development (GO:0046548)2.52460140
165cerebellar granule cell differentiation (GO:0021707)2.51783386
166adult walking behavior (GO:0007628)2.49909297
167DNA strand elongation involved in DNA replication (GO:0006271)2.49590353
168spinal cord motor neuron differentiation (GO:0021522)2.49167091
169neuronal action potential propagation (GO:0019227)2.48633836
170dendrite development (GO:0016358)2.44490679
171rRNA processing (GO:0006364)2.42732319
172establishment of mitochondrion localization (GO:0051654)2.41588961
173peptidyl-arginine omega-N-methylation (GO:0035247)2.40839530
174quinone biosynthetic process (GO:1901663)2.40513561
175ubiquinone biosynthetic process (GO:0006744)2.40513561
176histone arginine methylation (GO:0034969)2.40498252
177catecholamine transport (GO:0051937)2.39538235
178positive regulation of synapse assembly (GO:0051965)2.39413015
179mechanosensory behavior (GO:0007638)2.39031210
180positive regulation of protein homodimerization activity (GO:0090073)2.38069902
181rRNA metabolic process (GO:0016072)2.37167234
182telomere maintenance via telomere lengthening (GO:0010833)2.36276027

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.48349227
2EZH2_22144423_ChIP-Seq_EOC_Human4.44890234
3E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.43017997
4HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.16181168
5ZNF274_21170338_ChIP-Seq_K562_Hela2.97250529
6GBX2_23144817_ChIP-Seq_PC3_Human2.94102707
7SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.87242230
8KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.72304856
9CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.60260320
10EST1_17652178_ChIP-ChIP_JURKAT_Human2.45087042
11NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.40312454
12* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.33270405
13HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.25001988
14SALL1_21062744_ChIP-ChIP_HESCs_Human2.23380056
15TAF15_26573619_Chip-Seq_HEK293_Human2.21595881
16MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.20751692
17ETS1_20019798_ChIP-Seq_JURKAT_Human2.15398454
18CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.14595581
19MYC_18555785_ChIP-Seq_MESCs_Mouse2.13747039
20FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.10260182
21E2F4_17652178_ChIP-ChIP_JURKAT_Human2.00501123
22GABP_17652178_ChIP-ChIP_JURKAT_Human1.99152003
23FUS_26573619_Chip-Seq_HEK293_Human1.94220604
24THAP11_20581084_ChIP-Seq_MESCs_Mouse1.92522337
25PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.91187196
26YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.85997633
27JARID2_20064375_ChIP-Seq_MESCs_Mouse1.82089865
28* REST_21632747_ChIP-Seq_MESCs_Mouse1.78396084
29GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.76539962
30CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.69266590
31PADI4_21655091_ChIP-ChIP_MCF-7_Human1.66990391
32IRF1_19129219_ChIP-ChIP_H3396_Human1.65662075
33FLI1_27457419_Chip-Seq_LIVER_Mouse1.64063107
34YY1_21170310_ChIP-Seq_MESCs_Mouse1.61265938
35SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.60963446
36MYC_19030024_ChIP-ChIP_MESCs_Mouse1.57970703
37CTBP1_25329375_ChIP-Seq_LNCAP_Human1.57216490
38HOXB4_20404135_ChIP-ChIP_EML_Mouse1.52988359
39KDM5A_27292631_Chip-Seq_BREAST_Human1.52945096
40MYC_18358816_ChIP-ChIP_MESCs_Mouse1.50467692
41CTBP2_25329375_ChIP-Seq_LNCAP_Human1.49164216
42POU3F2_20337985_ChIP-ChIP_501MEL_Human1.47496909
43CREB1_15753290_ChIP-ChIP_HEK293T_Human1.47286106
44MYC_19079543_ChIP-ChIP_MESCs_Mouse1.45729891
45REST_18959480_ChIP-ChIP_MESCs_Mouse1.44789474
46HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.43994854
47* TP53_22573176_ChIP-Seq_HFKS_Human1.43337720
48BMI1_23680149_ChIP-Seq_NPCS_Mouse1.43335674
49EWS_26573619_Chip-Seq_HEK293_Human1.41004768
50EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.39517924
51EZH2_27304074_Chip-Seq_ESCs_Mouse1.35433682
52SRF_21415370_ChIP-Seq_HL-1_Mouse1.34260372
53ESR1_15608294_ChIP-ChIP_MCF-7_Human1.33993737
54MYC_18940864_ChIP-ChIP_HL60_Human1.33437341
55P300_19829295_ChIP-Seq_ESCs_Human1.32521363
56VDR_23849224_ChIP-Seq_CD4+_Human1.29874844
57E2F1_21310950_ChIP-Seq_MCF-7_Human1.29564246
58FOXP3_21729870_ChIP-Seq_TREG_Human1.28582579
59BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.27778711
60VDR_22108803_ChIP-Seq_LS180_Human1.26847923
61CIITA_25753668_ChIP-Seq_RAJI_Human1.26602903
62ER_23166858_ChIP-Seq_MCF-7_Human1.25465235
63CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.25378707
64RARB_27405468_Chip-Seq_BRAIN_Mouse1.24288958
65TTF2_22483619_ChIP-Seq_HELA_Human1.23013140
66ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.20587347
67CBP_20019798_ChIP-Seq_JUKART_Human1.19901033
68IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.19901033
69CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.19809159
70CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.19379049
71NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.19201732
72ELF1_17652178_ChIP-ChIP_JURKAT_Human1.19182417
73SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.18700083
74IGF1R_20145208_ChIP-Seq_DFB_Human1.18348987
75FOXM1_23109430_ChIP-Seq_U2OS_Human1.18333953
76XRN2_22483619_ChIP-Seq_HELA_Human1.17372515
77ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.17182089
78JARID2_20075857_ChIP-Seq_MESCs_Mouse1.16684372
79AR_21572438_ChIP-Seq_LNCaP_Human1.15533043
80KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.14798493
81PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.14204919
82ZFP57_27257070_Chip-Seq_ESCs_Mouse1.13952158
83MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.13271768
84SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.12989238
85EED_16625203_ChIP-ChIP_MESCs_Mouse1.11315182
86TP63_19390658_ChIP-ChIP_HaCaT_Human1.10920715
87EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.10037862
88OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.08732338
89SOX9_26525672_Chip-Seq_HEART_Mouse1.06677147
90SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.06167499
91PCGF2_27294783_Chip-Seq_ESCs_Mouse1.05973549
92EZH2_27294783_Chip-Seq_ESCs_Mouse1.04624520
93SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.04388093
94POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.02521776
95ELK1_19687146_ChIP-ChIP_HELA_Human1.01952049
96ELK1_22589737_ChIP-Seq_MCF10A_Human1.01128586
97FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.01000301
98* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.00975475
99* NANOG_19829295_ChIP-Seq_ESCs_Human1.00747966
100* SOX2_19829295_ChIP-Seq_ESCs_Human1.00747966
101FOXA1_27270436_Chip-Seq_PROSTATE_Human0.99894387
102FOXA1_25329375_ChIP-Seq_VCAP_Human0.99894387
103PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.98411534
104JUN_21703547_ChIP-Seq_K562_Human0.98281733
105FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.98041609
106SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.97749383
107TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.97731948
108SOX2_16153702_ChIP-ChIP_HESCs_Human0.97402530
109AR_21909140_ChIP-Seq_LNCAP_Human0.96796196
110GABP_19822575_ChIP-Seq_HepG2_Human0.96029099
111EZH2_18974828_ChIP-Seq_MESCs_Mouse0.96020406
112RNF2_18974828_ChIP-Seq_MESCs_Mouse0.96020406
113AR_20517297_ChIP-Seq_VCAP_Human0.95890918
114RNF2_27304074_Chip-Seq_NSC_Mouse0.95730240
115NCOR_22424771_ChIP-Seq_293T_Human0.95713534
116NELFA_20434984_ChIP-Seq_ESCs_Mouse0.94011911
117POU5F1_16153702_ChIP-ChIP_HESCs_Human0.93792961
118* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.93420871
119DCP1A_22483619_ChIP-Seq_HELA_Human0.93283878
120MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.92223929
121GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.92097707
122RNF2_27304074_Chip-Seq_ESCs_Mouse0.90288921
123FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.89083470
124SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.88791733
125E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.88171425
126ETV2_25802403_ChIP-Seq_MESCs_Mouse0.87876716
127MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.87861547
128NOTCH1_21737748_ChIP-Seq_TLL_Human0.87299872
129P53_22127205_ChIP-Seq_FIBROBLAST_Human0.87289864
130SMAD3_21741376_ChIP-Seq_EPCs_Human0.87058698
131RBPJ_22232070_ChIP-Seq_NCS_Mouse0.86527918
132* FOXA1_21572438_ChIP-Seq_LNCaP_Human0.86289238
133TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.85566279
134IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.85005820
135GATA3_21878914_ChIP-Seq_MCF-7_Human0.84708428
136FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.84223962
137GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.84219969
138UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.83865869
139HOXB7_26014856_ChIP-Seq_BT474_Human0.83686451
140* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.82699330
141POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.81794557

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.60553933
2MP0006292_abnormal_olfactory_placode4.54869654
3MP0004859_abnormal_synaptic_plasticity3.49931262
4MP0001529_abnormal_vocalization3.23281647
5MP0003950_abnormal_plasma_membrane2.82074330
6MP0003635_abnormal_synaptic_transmissio2.74249868
7MP0000569_abnormal_digit_pigmentation2.71730782
8MP0000372_irregular_coat_pigmentation2.49540141
9MP0003136_yellow_coat_color2.35169574
10MP0002272_abnormal_nervous_system2.31998303
11MP0001905_abnormal_dopamine_level2.28041242
12MP0009745_abnormal_behavioral_response2.27199136
13MP0002653_abnormal_ependyma_morphology2.26644244
14MP0002064_seizures2.23875771
15MP0006072_abnormal_retinal_apoptosis2.16551803
16MP0008995_early_reproductive_senescence2.14617373
17MP0004270_analgesia2.12222243
18MP0002572_abnormal_emotion/affect_behav2.10290698
19MP0005075_abnormal_melanosome_morpholog2.10177435
20MP0002063_abnormal_learning/memory/cond2.09682967
21MP0004885_abnormal_endolymph2.02281469
22MP0009046_muscle_twitch1.96884165
23MP0001486_abnormal_startle_reflex1.96465706
24MP0010094_abnormal_chromosome_stability1.89004198
25MP0009697_abnormal_copulation1.84251882
26MP0003786_premature_aging1.81812124
27MP0005423_abnormal_somatic_nervous1.80361027
28MP0003693_abnormal_embryo_hatching1.78890914
29MP0003111_abnormal_nucleus_morphology1.68015290
30MP0008057_abnormal_DNA_replication1.63108409
31MP0001440_abnormal_grooming_behavior1.61915381
32MP0002160_abnormal_reproductive_system1.61548020
33MP0008877_abnormal_DNA_methylation1.59127423
34MP0002067_abnormal_sensory_capabilities1.57771880
35MP0004043_abnormal_pH_regulation1.56489255
36MP0004133_heterotaxia1.55408277
37MP0003329_amyloid_beta_deposits1.55306647
38MP0003195_calcinosis1.54606570
39MP0005551_abnormal_eye_electrophysiolog1.52985632
40MP0005409_darkened_coat_color1.52809291
41MP0000778_abnormal_nervous_system1.50921231
42MP0008872_abnormal_physiological_respon1.50286362
43MP0000427_abnormal_hair_cycle1.47161947
44MP0002938_white_spotting1.47142447
45MP0002734_abnormal_mechanical_nocicepti1.46551045
46MP0003123_paternal_imprinting1.45507407
47MP0001188_hyperpigmentation1.42751161
48MP0004924_abnormal_behavior1.42608614
49MP0005386_behavior/neurological_phenoty1.42608614
50MP0001764_abnormal_homeostasis1.41746108
51MP0004142_abnormal_muscle_tone1.40470019
52MP0004145_abnormal_muscle_electrophysio1.40131884
53MP0005253_abnormal_eye_physiology1.39059501
54MP0000566_synostosis1.39059310
55MP0008260_abnormal_autophagy1.37158892
56MP0001293_anophthalmia1.36190463
57MP0008569_lethality_at_weaning1.35802472
58MP0002095_abnormal_skin_pigmentation1.34928010
59MP0005174_abnormal_tail_pigmentation1.33661793
60MP0002928_abnormal_bile_duct1.32889956
61MP0002557_abnormal_social/conspecific_i1.31398875
62MP0001968_abnormal_touch/_nociception1.25285315
63MP0008007_abnormal_cellular_replicative1.25096367
64MP0003806_abnormal_nucleotide_metabolis1.24291223
65MP0001501_abnormal_sleep_pattern1.23265072
66MP0004957_abnormal_blastocyst_morpholog1.23245499
67MP0002751_abnormal_autonomic_nervous1.22973891
68MP0004147_increased_porphyrin_level1.22637485
69MP0001929_abnormal_gametogenesis1.20957782
70MP0002210_abnormal_sex_determination1.20256859
71MP0002882_abnormal_neuron_morphology1.20174733
72MP0005389_reproductive_system_phenotype1.19380355
73MP0004233_abnormal_muscle_weight1.16899433
74MP0003646_muscle_fatigue1.15623965
75MP0005645_abnormal_hypothalamus_physiol1.15608880
76MP0002066_abnormal_motor_capabilities/c1.15360272
77MP0006036_abnormal_mitochondrial_physio1.14807977
78MP0005084_abnormal_gallbladder_morpholo1.14775520
79MP0003879_abnormal_hair_cell1.13927211
80MP0006035_abnormal_mitochondrial_morpho1.13012925
81MP0001485_abnormal_pinna_reflex1.12202562
82MP0000383_abnormal_hair_follicle1.11882947
83MP0002229_neurodegeneration1.11588529
84MP0003787_abnormal_imprinting1.10619513
85MP0003718_maternal_effect1.09702153
86MP0006276_abnormal_autonomic_nervous1.09549471
87MP0002234_abnormal_pharynx_morphology1.09261840
88MP0000631_abnormal_neuroendocrine_gland1.07779347
89MP0002638_abnormal_pupillary_reflex1.07342463
90MP0000751_myopathy1.06977188
91MP0001970_abnormal_pain_threshold1.06235649
92MP0003011_delayed_dark_adaptation1.06217541
93MP0002184_abnormal_innervation1.06117543
94MP0001963_abnormal_hearing_physiology1.05294841
95MP0004742_abnormal_vestibular_system1.04982095
96MP0002752_abnormal_somatic_nervous1.02782692
97MP0000026_abnormal_inner_ear1.02498477
98MP0003186_abnormal_redox_activity1.00730803
99MP0008932_abnormal_embryonic_tissue1.00481534
100MP0002152_abnormal_brain_morphology1.00207806
101MP0005395_other_phenotype0.98447834
102MP0000653_abnormal_sex_gland0.97923164
103MP0008058_abnormal_DNA_repair0.97715063
104MP0000955_abnormal_spinal_cord0.97274333
105MP0003890_abnormal_embryonic-extraembry0.96541995
106MP0002837_dystrophic_cardiac_calcinosis0.95260162
107MP0008875_abnormal_xenobiotic_pharmacok0.94811340
108MP0001919_abnormal_reproductive_system0.93841798
109MP0008961_abnormal_basal_metabolism0.93362854
110MP0005394_taste/olfaction_phenotype0.92248210
111MP0005499_abnormal_olfactory_system0.92248210
112MP0000015_abnormal_ear_pigmentation0.91691881
113MP0001145_abnormal_male_reproductive0.91277793
114MP0004215_abnormal_myocardial_fiber0.91203153
115MP0005646_abnormal_pituitary_gland0.90838513
116MP0002733_abnormal_thermal_nociception0.90380100
117MP0002736_abnormal_nociception_after0.89789226
118MP0002102_abnormal_ear_morphology0.88642406
119MP0002127_abnormal_cardiovascular_syste0.88238141
120MP0002277_abnormal_respiratory_mucosa0.88075388
121MP0003121_genomic_imprinting0.87983046
122MP0000920_abnormal_myelination0.87079899
123MP0003698_abnormal_male_reproductive0.86960560
124MP0003077_abnormal_cell_cycle0.85804975
125MP0000647_abnormal_sebaceous_gland0.85691291
126MP0003183_abnormal_peptide_metabolism0.85505396
127MP0004381_abnormal_hair_follicle0.84726815
128MP0003631_nervous_system_phenotype0.84582803
129MP0003137_abnormal_impulse_conducting0.83829184
130MP0003633_abnormal_nervous_system0.82819352
131MP0001119_abnormal_female_reproductive0.82069385
132MP0001986_abnormal_taste_sensitivity0.81638214
133MP0003938_abnormal_ear_development0.81326860
134MP0001502_abnormal_circadian_rhythm0.80986167
135MP0001984_abnormal_olfaction0.80431310
136MP0003861_abnormal_nervous_system0.78851165
137MP0009780_abnormal_chondrocyte_physiolo0.78240952
138MP0008789_abnormal_olfactory_epithelium0.77308380
139MP0005671_abnormal_response_to0.76493724
140MP0004811_abnormal_neuron_physiology0.74300536
141MP0009765_abnormal_xenobiotic_induced0.73334232
142MP0003632_abnormal_nervous_system0.72777926
143MP0004085_abnormal_heartbeat0.71894659
144MP0001324_abnormal_eye_pigmentation0.70581731
145MP0005410_abnormal_fertilization0.70304737
146MP0003937_abnormal_limbs/digits/tail_de0.69519063
147MP0001286_abnormal_eye_development0.68006571
148MP0002735_abnormal_chemical_nociception0.67748379
149MP0003315_abnormal_perineum_morphology0.67663110
150MP0005195_abnormal_posterior_eye0.67494585
151MP0000371_diluted_coat_color0.65759988
152MP0005391_vision/eye_phenotype0.65092428
153MP0000358_abnormal_cell_content/0.62348304
154MP0002019_abnormal_tumor_incidence0.60204452
155MP0005332_abnormal_amino_acid0.59907947
156MP0003252_abnormal_bile_duct0.59132945

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)3.88224256
2Epileptic encephalopathy (HP:0200134)3.80413633
3Pancreatic cysts (HP:0001737)3.60460785
4Molar tooth sign on MRI (HP:0002419)3.56172323
5Abnormality of midbrain morphology (HP:0002418)3.56172323
6Acute necrotizing encephalopathy (HP:0006965)3.53196716
7Cerebral hypomyelination (HP:0006808)3.52679764
8Increased hepatocellular lipid droplets (HP:0006565)3.40171295
9Medial flaring of the eyebrow (HP:0010747)3.38688029
10Pancreatic fibrosis (HP:0100732)3.25988600
11Birth length less than 3rd percentile (HP:0003561)3.24287292
12Abnormality of the labia minora (HP:0012880)3.23816367
13Chromsome breakage (HP:0040012)3.08768840
14Abnormal mitochondria in muscle tissue (HP:0008316)2.96354733
15Nephronophthisis (HP:0000090)2.95322060
16True hermaphroditism (HP:0010459)2.93644446
17Lipid accumulation in hepatocytes (HP:0006561)2.92140353
18Mitochondrial inheritance (HP:0001427)2.83610912
19Duplicated collecting system (HP:0000081)2.83372196
20Progressive macrocephaly (HP:0004481)2.73672026
21Acute encephalopathy (HP:0006846)2.73549373
22Abnormality of alanine metabolism (HP:0010916)2.73277527
23Hyperalaninemia (HP:0003348)2.73277527
24Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.73277527
25Increased CSF lactate (HP:0002490)2.71333297
26Broad-based gait (HP:0002136)2.71088820
27Chromosomal breakage induced by crosslinking agents (HP:0003221)2.68734190
28Methylmalonic aciduria (HP:0012120)2.62887631
29Hepatic necrosis (HP:0002605)2.60384029
30Pendular nystagmus (HP:0012043)2.58979315
31Cerebral edema (HP:0002181)2.56259458
32Nephrogenic diabetes insipidus (HP:0009806)2.55635862
33Congenital primary aphakia (HP:0007707)2.47180676
34Chronic hepatic failure (HP:0100626)2.44249135
35Abnormality of the renal cortex (HP:0011035)2.43925664
36Volvulus (HP:0002580)2.43727196
37Long nose (HP:0003189)2.43138752
38Delusions (HP:0000746)2.42197728
39Rough bone trabeculation (HP:0100670)2.41548170
40Renal cortical cysts (HP:0000803)2.41516115
41Hepatocellular necrosis (HP:0001404)2.41418731
42Gait imbalance (HP:0002141)2.40921015
43Abnormality of the renal medulla (HP:0100957)2.40663846
44Hypoplasia of the fovea (HP:0007750)2.39037396
45Aplasia/Hypoplasia of the fovea (HP:0008060)2.39037396
46Absent thumb (HP:0009777)2.36488647
47Aplastic anemia (HP:0001915)2.35798821
48Aplasia/Hypoplasia of the uvula (HP:0010293)2.34672856
49Abnormality of the renal collecting system (HP:0004742)2.34303703
50CNS hypomyelination (HP:0003429)2.34267655
51Congenital stationary night blindness (HP:0007642)2.30170318
52Unsteady gait (HP:0002317)2.29784832
53Urinary bladder sphincter dysfunction (HP:0002839)2.28552033
54Methylmalonic acidemia (HP:0002912)2.28217784
55Leukodystrophy (HP:0002415)2.27895256
56Abnormal rod and cone electroretinograms (HP:0008323)2.26213997
57Gastroesophageal reflux (HP:0002020)2.25025942
58Focal seizures (HP:0007359)2.24462394
59Cystic liver disease (HP:0006706)2.24014689
60Abnormality of chromosome stability (HP:0003220)2.23180381
61Myokymia (HP:0002411)2.22300170
62Absent forearm bone (HP:0003953)2.21769319
63Aplasia involving forearm bones (HP:0009822)2.21769319
64Meckel diverticulum (HP:0002245)2.20673037
65Abnormality of the fovea (HP:0000493)2.20483728
66Absent rod-and cone-mediated responses on ERG (HP:0007688)2.19977517
67Bile duct proliferation (HP:0001408)2.18307104
68Abnormal biliary tract physiology (HP:0012439)2.18307104
69Postnatal microcephaly (HP:0005484)2.17586976
70Sloping forehead (HP:0000340)2.17576660
71Absent radius (HP:0003974)2.17194864
72Oligodactyly (hands) (HP:0001180)2.16569149
73Sclerocornea (HP:0000647)2.15274789
74Type I transferrin isoform profile (HP:0003642)2.13762940
75Abnormality of the ileum (HP:0001549)2.13555565
76Hypothermia (HP:0002045)2.12346435
77Hypoplasia of the pons (HP:0012110)2.11928666
78Increased serum pyruvate (HP:0003542)2.10763507
79Abnormality of glycolysis (HP:0004366)2.10763507
80Abnormality of the pons (HP:0007361)2.10758554
81Lactic acidosis (HP:0003128)2.10357252
82Renal Fanconi syndrome (HP:0001994)2.08806775
83Tubulointerstitial nephritis (HP:0001970)2.06882281
84Visual hallucinations (HP:0002367)2.06662353
85Absence seizures (HP:0002121)2.06362240
86Cellular immunodeficiency (HP:0005374)2.06281818
87Microvesicular hepatic steatosis (HP:0001414)2.06201987
88Epileptiform EEG discharges (HP:0011182)2.05558940
89Horseshoe kidney (HP:0000085)2.04875199
90Premature graying of hair (HP:0002216)2.04543789
91Postaxial foot polydactyly (HP:0001830)2.04532843
92Type 2 muscle fiber atrophy (HP:0003554)2.03600217
93Progressive microcephaly (HP:0000253)2.03369969
94Abnormality of cochlea (HP:0000375)2.03260967
95Morphological abnormality of the inner ear (HP:0011390)2.00979473
96Abnormality of binocular vision (HP:0011514)2.00672769
97Diplopia (HP:0000651)2.00672769
98Aplasia/Hypoplasia of the tongue (HP:0010295)2.00419473
99Abnormal number of erythroid precursors (HP:0012131)2.00046110
100Pancytopenia (HP:0001876)1.99892326
1013-Methylglutaconic aciduria (HP:0003535)1.99666438
102Progressive cerebellar ataxia (HP:0002073)1.98368877
103Spastic gait (HP:0002064)1.98257246
104Stenosis of the external auditory canal (HP:0000402)1.97944619
105Atonic seizures (HP:0010819)1.97593778
106Generalized tonic-clonic seizures (HP:0002069)1.96352981
107Duplication of thumb phalanx (HP:0009942)1.95793223
108Hyperventilation (HP:0002883)1.95488964
109EEG with generalized epileptiform discharges (HP:0011198)1.93173680
110Genital tract atresia (HP:0001827)1.93154760
111Type II lissencephaly (HP:0007260)1.93142995
112Dialeptic seizures (HP:0011146)1.93103146
113Tubular atrophy (HP:0000092)1.92324100
114Increased intramyocellular lipid droplets (HP:0012240)1.91404164
115IgG deficiency (HP:0004315)1.90852781
116Bone marrow hypocellularity (HP:0005528)1.90562062
117Progressive inability to walk (HP:0002505)1.89904156
118Medulloblastoma (HP:0002885)1.89364333
119Vaginal atresia (HP:0000148)1.89232463
120Absent septum pellucidum (HP:0001331)1.88503952
121Gaze-evoked nystagmus (HP:0000640)1.87834773
122Optic disc pallor (HP:0000543)1.87666115
123Lethargy (HP:0001254)1.87139829
124Progressive external ophthalmoplegia (HP:0000590)1.86919120
125Decreased activity of mitochondrial respiratory chain (HP:0008972)1.85387171
126Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.85387171
127Truncal ataxia (HP:0002078)1.84903314
128Abnormality of the columella (HP:0009929)1.84879689
129Short tibia (HP:0005736)1.84861838
130Degeneration of the lateral corticospinal tracts (HP:0002314)1.83766810
131Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.83766810
132Abnormality of the septum pellucidum (HP:0007375)1.83684432
133Patellar aplasia (HP:0006443)1.83423247
134Lissencephaly (HP:0001339)1.83342562
135Aplasia/Hypoplasia of the sacrum (HP:0008517)1.82901847
136Increased serum lactate (HP:0002151)1.81629937
137Abnormality of cells of the erythroid lineage (HP:0012130)1.80629016
138Abnormality of the axillary hair (HP:0100134)1.80125994
139Abnormality of secondary sexual hair (HP:0009888)1.80125994
140Breast hypoplasia (HP:0003187)1.79854133
141Abnormal number of incisors (HP:0011064)1.79229913
142Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.79154036
143Oculomotor apraxia (HP:0000657)1.78108980
144Hyperglycinemia (HP:0002154)1.77844157
145Delayed myelination (HP:0012448)1.77575986
146Abnormality of vitamin B metabolism (HP:0004340)1.77464783
147Intestinal atresia (HP:0011100)1.77303450
148Poor speech (HP:0002465)1.77197615
149Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.77128898
150Abnormal protein glycosylation (HP:0012346)1.75589461
151Abnormal glycosylation (HP:0012345)1.75589461
152Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.75589461
153Abnormal protein N-linked glycosylation (HP:0012347)1.75589461
154Abnormality of the preputium (HP:0100587)1.74646308
155Nephroblastoma (Wilms tumor) (HP:0002667)1.73916959
156Dicarboxylic aciduria (HP:0003215)1.73811253
157Abnormality of dicarboxylic acid metabolism (HP:0010995)1.73811253
158Cortical visual impairment (HP:0100704)1.73096701
159Abnormality of the vitamin B12 metabolism (HP:0004341)1.72765318
160Triphalangeal thumb (HP:0001199)1.72591251
161Emotional lability (HP:0000712)1.71943639
162Fibular aplasia (HP:0002990)1.71891035
163Abnormality of renal resorption (HP:0011038)1.71331404
164Generalized myoclonic seizures (HP:0002123)1.71016315
165Overfolded helix (HP:0000396)1.70903295
166Septo-optic dysplasia (HP:0100842)1.68934893
167Widely spaced teeth (HP:0000687)1.68574592
168Abnormal hair whorl (HP:0010721)1.68351063
169Aplasia/Hypoplasia of the tibia (HP:0005772)1.68142635
170Exercise intolerance (HP:0003546)1.68017588
171Colon cancer (HP:0003003)1.67843275
172Reticulocytopenia (HP:0001896)1.66500637
173Aplasia/Hypoplasia of the patella (HP:0006498)1.66497023

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K23.51607935
2INSRR3.31628366
3CASK3.18364421
4TRIM283.09363554
5CDK193.09247659
6FRK3.09218760
7BRSK23.06931593
8TNIK2.79886930
9VRK22.75899034
10EPHA42.67058663
11MAP3K122.48780297
12ZAK2.44568624
13PNCK2.38450473
14TSSK62.35900717
15NTRK32.34979120
16BUB12.34395511
17TXK2.26295384
18CCNB12.22456562
19NME11.96459055
20MARK11.83613258
21MAP3K131.82671578
22CDC71.80500300
23GRK11.73725268
24MAP2K71.71088642
25MKNK21.69437152
26ADRBK21.66791652
27BCKDK1.57027261
28NEK61.55985314
29MKNK11.53907162
30SRPK11.50971259
31PLK21.49123564
32PRPF4B1.37168952
33PLK31.37151404
34CAMKK21.36355602
35MINK11.35121039
36MUSK1.33699909
37PLK41.29466891
38DAPK11.29427306
39OXSR11.25703030
40AKT31.24290265
41TTK1.22521133
42MST41.21504046
43PBK1.21116375
44PKN11.20542666
45BRAF1.20000634
46TLK11.17287599
47CSNK1G31.17174090
48BRSK11.15706459
49EIF2AK31.15485421
50WEE11.15054447
51MAP3K41.14553789
52CAMK2B1.01960490
53WNK41.01675719
54ERBB31.01417700
55FES0.98473801
56UHMK10.98441839
57CLK10.93305859
58PRKD30.92409478
59MAPKAPK50.91702179
60KDR0.90987413
61ROCK20.90755825
62CAMK10.88960498
63CSNK1G20.88358974
64PDK20.87132036
65DAPK20.86415287
66NTRK20.86223931
67BCR0.85618317
68CSNK1G10.83600090
69RIPK40.82560479
70STK160.81830239
71BMPR20.81780889
72STK240.80765154
73PAK30.79174207
74BMPR1B0.78743846
75KSR10.78469089
76MAP2K40.78354157
77RPS6KA50.76974270
78STK38L0.76441932
79CAMK2D0.76165569
80MAPK130.75559345
81MAP3K60.75226598
82CAMK2A0.75016401
83CDK11A0.74413115
84TESK20.73698622
85CDK180.72776613
86VRK10.71800237
87PLK10.71432198
88WNK30.68963802
89PRKCI0.68729194
90CDK150.68491044
91NUAK10.67601853
92PIK3CA0.66780915
93CSNK1E0.66378828
94NEK20.66336350
95CAMK1G0.64290373
96CHEK20.63093869
97TEC0.62773942
98PASK0.59955396
99EIF2AK20.59776992
100DYRK1A0.59427067
101ATR0.57801898
102CDK140.57321936
103MARK20.57038010
104CSNK2A20.56096495
105CAMK40.55992628
106YES10.55665858
107AURKA0.54015297
108CDK50.53106817
109CDK70.52456872
110CAMKK10.50757453
111IKBKE0.50656232
112CDK80.50234043
113DYRK30.49517986
114CDK40.48933239
115CSNK1A1L0.48849442
116SIK20.48271055
117PRKCE0.47783080
118CDC42BPA0.45891387
119IRAK10.44501224
120ATM0.44191781
121TAOK30.43037879
122AURKB0.42770266
123CHEK10.42727480
124PINK10.42702815
125CSNK2A10.42683853
126CDK30.42387606
127GRK70.41952699
128CSNK1A10.40756097
129ACVR1B0.40065932
130IKBKB0.39952996
131CDK10.39883208
132PRKCG0.39861948
133DYRK20.39807094
134ITK0.39713956
135CDK20.38136624
136PRKACB0.37537662
137PRKD20.37520348
138PIM10.37445658
139MELK0.37444742
140EIF2AK10.37378628
141IRAK40.37324447
142TAF10.37028857
143SGK2230.36958128
144MARK30.36730070
145NLK0.36552682
146NEK10.36448545
147STK40.36335398
148TNK20.36112141
149PRKCQ0.35607327
150GRK60.35499512
151STK390.35302618

Predicted pathways (KEGG)

RankGene SetZ-score
1Mismatch repair_Homo sapiens_hsa034303.37515979
2RNA polymerase_Homo sapiens_hsa030203.28458741
3Nicotine addiction_Homo sapiens_hsa050333.18141477
4DNA replication_Homo sapiens_hsa030302.81841049
5Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.74115797
6Oxidative phosphorylation_Homo sapiens_hsa001902.60539932
7Spliceosome_Homo sapiens_hsa030402.34607001
8Parkinsons disease_Homo sapiens_hsa050122.26808282
9Ribosome_Homo sapiens_hsa030101.98405693
10Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.97729683
11Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.93985685
12Synaptic vesicle cycle_Homo sapiens_hsa047211.89121128
13Protein export_Homo sapiens_hsa030601.87997956
14Alzheimers disease_Homo sapiens_hsa050101.86410780
15RNA degradation_Homo sapiens_hsa030181.83941842
16Taste transduction_Homo sapiens_hsa047421.83497220
17Homologous recombination_Homo sapiens_hsa034401.82747003
18Glutamatergic synapse_Homo sapiens_hsa047241.78750083
19GABAergic synapse_Homo sapiens_hsa047271.76960111
20Long-term potentiation_Homo sapiens_hsa047201.76273912
21Oocyte meiosis_Homo sapiens_hsa041141.74748844
22Amphetamine addiction_Homo sapiens_hsa050311.70961012
23Nucleotide excision repair_Homo sapiens_hsa034201.70168610
24Selenocompound metabolism_Homo sapiens_hsa004501.69352097
25Fanconi anemia pathway_Homo sapiens_hsa034601.68089561
26Circadian entrainment_Homo sapiens_hsa047131.66829729
27Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.65776985
28RNA transport_Homo sapiens_hsa030131.65649527
29Non-homologous end-joining_Homo sapiens_hsa034501.64975947
30Base excision repair_Homo sapiens_hsa034101.61671960
31Huntingtons disease_Homo sapiens_hsa050161.60615705
32Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.60163489
33Morphine addiction_Homo sapiens_hsa050321.60131716
34Phototransduction_Homo sapiens_hsa047441.53964542
35Cardiac muscle contraction_Homo sapiens_hsa042601.51315050
36Pyrimidine metabolism_Homo sapiens_hsa002401.51096540
37Serotonergic synapse_Homo sapiens_hsa047261.47232259
38Cell cycle_Homo sapiens_hsa041101.46578171
39Primary immunodeficiency_Homo sapiens_hsa053401.46065200
40Proteasome_Homo sapiens_hsa030501.41922362
41Collecting duct acid secretion_Homo sapiens_hsa049661.39605853
42Dopaminergic synapse_Homo sapiens_hsa047281.38235882
43Purine metabolism_Homo sapiens_hsa002301.35082727
44Insulin secretion_Homo sapiens_hsa049111.33117190
45Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.28257371
46Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.23889963
47Olfactory transduction_Homo sapiens_hsa047401.23009818
48Basal transcription factors_Homo sapiens_hsa030221.19532769
49Propanoate metabolism_Homo sapiens_hsa006401.18651332
50Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.15839036
51Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.14871750
52Long-term depression_Homo sapiens_hsa047301.12742799
53Calcium signaling pathway_Homo sapiens_hsa040201.08179003
54Butanoate metabolism_Homo sapiens_hsa006501.08015339
55Salivary secretion_Homo sapiens_hsa049701.07349601
56Peroxisome_Homo sapiens_hsa041461.05192796
57Oxytocin signaling pathway_Homo sapiens_hsa049211.03098944
58Nitrogen metabolism_Homo sapiens_hsa009101.02796935
59Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.00859869
60Renin secretion_Homo sapiens_hsa049240.96829698
61Caffeine metabolism_Homo sapiens_hsa002320.96226011
62Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.94804551
63One carbon pool by folate_Homo sapiens_hsa006700.92068299
64Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.91663976
65Vibrio cholerae infection_Homo sapiens_hsa051100.88791097
66Circadian rhythm_Homo sapiens_hsa047100.87818436
67mRNA surveillance pathway_Homo sapiens_hsa030150.83221048
68Gastric acid secretion_Homo sapiens_hsa049710.79502005
69Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.78573546
70Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.78526680
71Cocaine addiction_Homo sapiens_hsa050300.77420655
72Intestinal immune network for IgA production_Homo sapiens_hsa046720.77149888
73Cholinergic synapse_Homo sapiens_hsa047250.74708408
74Aldosterone synthesis and secretion_Homo sapiens_hsa049250.73343163
75Folate biosynthesis_Homo sapiens_hsa007900.73101062
76Chemical carcinogenesis_Homo sapiens_hsa052040.72447557
77Linoleic acid metabolism_Homo sapiens_hsa005910.71144382
78Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.68115195
79Asthma_Homo sapiens_hsa053100.67831057
80Regulation of autophagy_Homo sapiens_hsa041400.65946035
81Steroid hormone biosynthesis_Homo sapiens_hsa001400.64395200
82Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.63659164
83Tryptophan metabolism_Homo sapiens_hsa003800.62378943
84Steroid biosynthesis_Homo sapiens_hsa001000.60124411
85Vitamin B6 metabolism_Homo sapiens_hsa007500.59550021
86Primary bile acid biosynthesis_Homo sapiens_hsa001200.59244747
87Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.58428740
88Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.57389804
89Pentose and glucuronate interconversions_Homo sapiens_hsa000400.56021767
90Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.55601522
91SNARE interactions in vesicular transport_Homo sapiens_hsa041300.55015838
92Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.51801902
93Vascular smooth muscle contraction_Homo sapiens_hsa042700.51637405
94cAMP signaling pathway_Homo sapiens_hsa040240.50326497
95Axon guidance_Homo sapiens_hsa043600.48268257
96Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.48007128
97Glutathione metabolism_Homo sapiens_hsa004800.47066453
98Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.47060454
99Melanogenesis_Homo sapiens_hsa049160.45846147
100Antigen processing and presentation_Homo sapiens_hsa046120.45564289
101Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.45260592
102Drug metabolism - other enzymes_Homo sapiens_hsa009830.45181019
103Cysteine and methionine metabolism_Homo sapiens_hsa002700.44397330
104alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.43564168
105Pancreatic secretion_Homo sapiens_hsa049720.41164245
106Alcoholism_Homo sapiens_hsa050340.39789873
107Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.39213481
108Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.39027474
109Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.38690399
110Cyanoamino acid metabolism_Homo sapiens_hsa004600.37533561
111p53 signaling pathway_Homo sapiens_hsa041150.36993738
112Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.36567850
113Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.36542967
114Wnt signaling pathway_Homo sapiens_hsa043100.36516864
115Metabolic pathways_Homo sapiens_hsa011000.36456362
116GnRH signaling pathway_Homo sapiens_hsa049120.36443672
117Retinol metabolism_Homo sapiens_hsa008300.36170217
118Systemic lupus erythematosus_Homo sapiens_hsa053220.35642322
119Epstein-Barr virus infection_Homo sapiens_hsa051690.35287478
120Gap junction_Homo sapiens_hsa045400.33917347
121Fructose and mannose metabolism_Homo sapiens_hsa000510.32825696
122Biosynthesis of amino acids_Homo sapiens_hsa012300.32505385
123Dilated cardiomyopathy_Homo sapiens_hsa054140.31237470
124Ether lipid metabolism_Homo sapiens_hsa005650.30739336
125Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.30286241
126Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.29325960
127Fatty acid elongation_Homo sapiens_hsa000620.28607306
128Sphingolipid metabolism_Homo sapiens_hsa006000.25290421
129Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.24805135
130Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.24607739
131Autoimmune thyroid disease_Homo sapiens_hsa053200.24373368
132Maturity onset diabetes of the young_Homo sapiens_hsa049500.24269507
133cGMP-PKG signaling pathway_Homo sapiens_hsa040220.22984027
134Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.22489896
135Phosphatidylinositol signaling system_Homo sapiens_hsa040700.21828766
136Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.20421064
137beta-Alanine metabolism_Homo sapiens_hsa004100.16502543
138Sulfur metabolism_Homo sapiens_hsa009200.16497323
139Allograft rejection_Homo sapiens_hsa053300.14733456
140Type I diabetes mellitus_Homo sapiens_hsa049400.13335893
141Herpes simplex infection_Homo sapiens_hsa051680.12673902
142N-Glycan biosynthesis_Homo sapiens_hsa005100.12361411
143RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.12178908
144Arachidonic acid metabolism_Homo sapiens_hsa005900.11080351
145Hematopoietic cell lineage_Homo sapiens_hsa046400.10849367

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