GPATCH4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1daunorubicin metabolic process (GO:0044597)6.60810620
2polyketide metabolic process (GO:0030638)6.60810620
3doxorubicin metabolic process (GO:0044598)6.60810620
4protein localization to kinetochore (GO:0034501)5.46983667
5formation of translation preinitiation complex (GO:0001731)5.11667136
6ribosomal small subunit biogenesis (GO:0042274)5.10048117
7regulation of nuclear cell cycle DNA replication (GO:0033262)5.07199132
8ribosome biogenesis (GO:0042254)4.90734079
9ribosome assembly (GO:0042255)4.79573233
10establishment of integrated proviral latency (GO:0075713)4.75700969
11rRNA modification (GO:0000154)4.74343522
12ribonucleoprotein complex biogenesis (GO:0022613)4.61071899
13DNA replication checkpoint (GO:0000076)4.56228944
14pseudouridine synthesis (GO:0001522)4.51896331
15chaperone-mediated protein transport (GO:0072321)4.50777476
16mitotic sister chromatid segregation (GO:0000070)4.50737600
17maturation of SSU-rRNA (GO:0030490)4.45949664
18rRNA methylation (GO:0031167)4.43984765
19ribosomal small subunit assembly (GO:0000028)4.35709254
20protein localization to chromosome, centromeric region (GO:0071459)4.34001695
21DNA replication-dependent nucleosome organization (GO:0034723)4.30350589
22DNA replication-dependent nucleosome assembly (GO:0006335)4.30350589
23mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.27837269
24DNA unwinding involved in DNA replication (GO:0006268)4.25985652
25establishment of protein localization to mitochondrial membrane (GO:0090151)4.22039753
26rRNA transcription (GO:0009303)4.16968020
27DNA replication initiation (GO:0006270)4.16705497
28transcription elongation from RNA polymerase III promoter (GO:0006385)4.16431879
29termination of RNA polymerase III transcription (GO:0006386)4.16431879
30aminoglycoside antibiotic metabolic process (GO:0030647)4.13521021
31regulation of mitochondrial translation (GO:0070129)4.07806427
32regulation of telomere maintenance via telomerase (GO:0032210)4.04347038
33regulation of mammary gland epithelial cell proliferation (GO:0033599)4.03556480
34negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)4.01868129
35negative regulation of telomerase activity (GO:0051974)4.00110746
36viral transcription (GO:0019083)3.88496596
37negative regulation of epidermis development (GO:0045683)3.87880090
38histone H4-K12 acetylation (GO:0043983)3.86674037
39negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.84601927
40negative regulation of cell cycle G2/M phase transition (GO:1902750)3.82580508
41regulation of translation in response to stress (GO:0043555)3.82176746
42sister chromatid segregation (GO:0000819)3.77133002
43translational termination (GO:0006415)3.77042848
44maturation of 5.8S rRNA (GO:0000460)3.70939754
45rRNA processing (GO:0006364)3.70108030
46nuclear pore organization (GO:0006999)3.67858032
47nuclear pore complex assembly (GO:0051292)3.67510827
48chromatin remodeling at centromere (GO:0031055)3.67006650
49ribosomal large subunit biogenesis (GO:0042273)3.65834155
50cellular component biogenesis (GO:0044085)3.63274135
51cullin deneddylation (GO:0010388)3.61480915
52heterochromatin organization (GO:0070828)3.60243808
53regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.59475010
54negative regulation of ligase activity (GO:0051352)3.58482881
55negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.58482881
56establishment of viral latency (GO:0019043)3.58356031
57rRNA metabolic process (GO:0016072)3.57002128
58maintenance of protein location in nucleus (GO:0051457)3.56398568
59protein targeting to mitochondrion (GO:0006626)3.56079876
60DNA strand elongation involved in DNA replication (GO:0006271)3.55428435
61anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.54064171
62energy coupled proton transport, down electrochemical gradient (GO:0015985)3.53325761
63ATP synthesis coupled proton transport (GO:0015986)3.53325761
64mitochondrial RNA metabolic process (GO:0000959)3.51423656
65mitotic metaphase plate congression (GO:0007080)3.51048520
66negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.50759903
67negative regulation of telomere maintenance (GO:0032205)3.49412657
68negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147)3.47168870
69positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.46311183
70protein deneddylation (GO:0000338)3.42967490
71DNA strand elongation (GO:0022616)3.42565987
72nucleobase biosynthetic process (GO:0046112)3.42041608
73IMP biosynthetic process (GO:0006188)3.39718337
74telomere maintenance via semi-conservative replication (GO:0032201)3.38662278
75DNA duplex unwinding (GO:0032508)3.38465951
76translational initiation (GO:0006413)3.38417141
77nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.36776514
78DNA geometric change (GO:0032392)3.36593278
79DNA damage response, detection of DNA damage (GO:0042769)3.34680295
80positive regulation of DNA-dependent DNA replication (GO:2000105)3.34072989
81nucleobase-containing small molecule interconversion (GO:0015949)3.33951929
82translational elongation (GO:0006414)3.32557328
83negative regulation of epidermal cell differentiation (GO:0045605)3.31409041
84establishment of protein localization to mitochondrion (GO:0072655)3.27779034
85histone H4-K8 acetylation (GO:0043982)3.27020659
86histone H4-K5 acetylation (GO:0043981)3.27020659
87viral mRNA export from host cell nucleus (GO:0046784)3.26330209
88DNA deamination (GO:0045006)3.26170109
89negative regulation of mRNA processing (GO:0050686)3.25441321
90DNA-templated transcription, termination (GO:0006353)3.24946802
91regulation of translational fidelity (GO:0006450)3.24739463
92termination of RNA polymerase II transcription (GO:0006369)3.24255547
93mitotic nuclear envelope disassembly (GO:0007077)3.22600631
94ncRNA processing (GO:0034470)3.22269198
95protein localization to mitochondrion (GO:0070585)3.21879220
96SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.20947466
97negative regulation of RNA splicing (GO:0033119)3.20640781
98regulation of response to osmotic stress (GO:0047484)3.19948747
99chromatin assembly (GO:0031497)3.18636765
100DNA replication-independent nucleosome assembly (GO:0006336)3.17093992
101DNA replication-independent nucleosome organization (GO:0034724)3.17093992
102somite rostral/caudal axis specification (GO:0032525)3.16538787
103transcription-coupled nucleotide-excision repair (GO:0006283)3.16401935
104histone exchange (GO:0043486)3.14460495
105cotranslational protein targeting to membrane (GO:0006613)3.12695756
106ncRNA metabolic process (GO:0034660)3.12383101
107mitotic chromosome condensation (GO:0007076)3.12307124
108protein targeting to ER (GO:0045047)3.11607229
109tRNA methylation (GO:0030488)3.11474679
110regulation of translational termination (GO:0006449)3.11115912
111folic acid-containing compound biosynthetic process (GO:0009396)3.10240718
112IMP metabolic process (GO:0046040)3.10087067
113spliceosomal complex assembly (GO:0000245)3.08946078
114mRNA splicing, via spliceosome (GO:0000398)3.06679575
115RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)3.06679575
116regulation of MHC class I biosynthetic process (GO:0045343)3.05206248
117positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.05027788
118RNA splicing, via transesterification reactions (GO:0000375)3.04579636
119notochord development (GO:0030903)3.03685856
120purine nucleobase biosynthetic process (GO:0009113)3.03611137
121regulation of transcription from RNA polymerase I promoter (GO:0006356)3.03464308
122amino acid activation (GO:0043038)3.02708501
123tRNA aminoacylation (GO:0043039)3.02708501
124telomere maintenance via telomerase (GO:0007004)3.02452520
125mitotic sister chromatid cohesion (GO:0007064)3.02425412
126muscle organ morphogenesis (GO:0048644)3.01613608
127transcription from RNA polymerase I promoter (GO:0006360)3.01033816
128tRNA aminoacylation for protein translation (GO:0006418)3.01005852
129negative regulation of mRNA metabolic process (GO:1903312)3.00630778
130spliceosomal snRNP assembly (GO:0000387)3.00077603
131translation (GO:0006412)2.99516295
132viral life cycle (GO:0019058)2.99394955
133termination of RNA polymerase I transcription (GO:0006363)2.98905769
134quinone metabolic process (GO:1901661)2.98131862
135mitochondrial DNA replication (GO:0006264)2.97062640
136mitotic recombination (GO:0006312)2.94891418
137pteridine-containing compound biosynthetic process (GO:0042559)2.94364526
138nuclear envelope disassembly (GO:0051081)2.94206428
139membrane disassembly (GO:0030397)2.94206428
140establishment of protein localization to endoplasmic reticulum (GO:0072599)2.93778501
141regulation of double-strand break repair via homologous recombination (GO:0010569)2.93749406
142transcription from mitochondrial promoter (GO:0006390)2.92493456
143protein localization to endoplasmic reticulum (GO:0070972)2.91259361
144cellular protein complex disassembly (GO:0043624)2.91247491
145proteasome assembly (GO:0043248)2.89988615
146metaphase plate congression (GO:0051310)2.89346764
147CENP-A containing nucleosome assembly (GO:0034080)2.89017974
148telomere maintenance via recombination (GO:0000722)2.88633259
149telomere maintenance via telomere lengthening (GO:0010833)2.87887551
150pore complex assembly (GO:0046931)2.83332481
151regulation of telomerase activity (GO:0051972)2.82839533

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.16954305
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.28952517
3NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.87666287
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.49482134
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.43831652
6KLF5_18264089_ChIP-ChIP_MESCs_Mouse3.13087755
7KLF4_18264089_ChIP-ChIP_MESCs_Mouse3.13087755
8KLF2_18264089_ChIP-ChIP_MESCs_Mouse3.13087755
9MYC_19079543_ChIP-ChIP_MESCs_Mouse3.05746133
10KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.05223057
11BP1_19119308_ChIP-ChIP_Hs578T_Human3.03845139
12FOXM1_23109430_ChIP-Seq_U2OS_Human2.86487322
13EST1_17652178_ChIP-ChIP_JURKAT_Human2.83990478
14FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.83913668
15* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.83787692
16MYC_18358816_ChIP-ChIP_MESCs_Mouse2.79198636
17* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.54369027
18ETS1_20019798_ChIP-Seq_JURKAT_Human2.52261122
19TP63_19390658_ChIP-ChIP_HaCaT_Human2.50527235
20CREB1_15753290_ChIP-ChIP_HEK293T_Human2.48950861
21CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.44438826
22GABP_17652178_ChIP-ChIP_JURKAT_Human2.41236715
23HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.11231067
24XRN2_22483619_ChIP-Seq_HELA_Human2.07304206
25POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.05372441
26MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.92917519
27FOXP3_21729870_ChIP-Seq_TREG_Human1.92597106
28SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.92070203
29VDR_23849224_ChIP-Seq_CD4+_Human1.91763930
30NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.89588970
31NELFA_20434984_ChIP-Seq_ESCs_Mouse1.88478892
32NOTCH1_21737748_ChIP-Seq_TLL_Human1.88296984
33MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.86754242
34POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.86036629
35NANOG_18555785_ChIP-Seq_MESCs_Mouse1.84188990
36E2F1_18555785_ChIP-Seq_MESCs_Mouse1.84157250
37* YY1_21170310_ChIP-Seq_MESCs_Mouse1.84017447
38* TTF2_22483619_ChIP-Seq_HELA_Human1.74198826
39POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.72003385
40* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.71499696
41STAT3_1855785_ChIP-Seq_MESCs_Mouse1.61396421
42MYC_22102868_ChIP-Seq_BL_Human1.61346870
43TCF3_18692474_ChIP-Seq_MEFs_Mouse1.60593618
44GABP_19822575_ChIP-Seq_HepG2_Human1.60253244
45AR_21909140_ChIP-Seq_LNCAP_Human1.58769036
46DCP1A_22483619_ChIP-Seq_HELA_Human1.57891172
47* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.53745014
48MYCN_18555785_ChIP-Seq_MESCs_Mouse1.52022271
49THAP11_20581084_ChIP-Seq_MESCs_Mouse1.51439454
50ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.46790235
51NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.43296531
52ELF1_17652178_ChIP-ChIP_JURKAT_Human1.42885395
53PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.42475548
54TCF3_18692474_ChIP-Seq_MESCs_Mouse1.41620907
55KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.40588011
56SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.39938166
57ELK1_19687146_ChIP-ChIP_HELA_Human1.37963966
58DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.37403635
59E2F1_21310950_ChIP-Seq_MCF-7_Human1.34518285
60IRF1_19129219_ChIP-ChIP_H3396_Human1.34467352
61CIITA_25753668_ChIP-Seq_RAJI_Human1.33878460
62KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.31621748
63SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.31619330
64SOX2_18555785_ChIP-Seq_MESCs_Mouse1.29956914
65* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.28011877
66TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.26996062
67CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.26100009
68ZFX_18555785_ChIP-Seq_MESCs_Mouse1.26070105
69NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.23571170
70MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.21911838
71* KDM5A_27292631_Chip-Seq_BREAST_Human1.20854359
72ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.18932872
73EGR1_19374776_ChIP-ChIP_THP-1_Human1.18091759
74TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.15270470
75CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.14769634
76CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.13544062
77* SRF_21415370_ChIP-Seq_HL-1_Mouse1.13412237
78DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.12623911
79OCT4_18692474_ChIP-Seq_MEFs_Mouse1.11740578
80RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.11323436
81KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.10695050
82KLF4_18555785_ChIP-Seq_MESCs_Mouse1.07538306
83NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.05540171
84ZNF263_19887448_ChIP-Seq_K562_Human1.04770030
85CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.04378422
86HOXB4_20404135_ChIP-ChIP_EML_Mouse1.03931555
87* ELK1_22589737_ChIP-Seq_MCF10A_Human1.03436247
88CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.02385256
89E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.02250259
90POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.02240767
91ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.00948065
92FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.00591931
93* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.00497492
94SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.99815516
95SOX2_18692474_ChIP-Seq_MEFs_Mouse0.99438575
96E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.98359661
97* ERG_20887958_ChIP-Seq_HPC-7_Mouse0.98209045
98ESR1_15608294_ChIP-ChIP_MCF-7_Human0.98183728
99NANOG_18692474_ChIP-Seq_MEFs_Mouse0.96416220
100CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.96399531
101BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.93734483
102PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.92538557
103NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.92115854
104GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.91149002
105* CHD1_26751641_Chip-Seq_LNCaP_Human0.89542705
106MYC_18940864_ChIP-ChIP_HL60_Human0.89428566
107HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.89380744
108CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.89314968
109HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.88121785
110TBX5_21415370_ChIP-Seq_HL-1_Mouse0.87301952
111NANOG_21062744_ChIP-ChIP_HESCs_Human0.87039804
112* SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.86385278
113CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.86179184
114TFEB_21752829_ChIP-Seq_HELA_Human0.85908126
115PADI4_21655091_ChIP-ChIP_MCF-7_Human0.84877722
116ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.84801528
117SOX17_20123909_ChIP-Seq_XEN_Mouse0.84347566
118ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.83888808
119SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.80834496
120FOXP1_21924763_ChIP-Seq_HESCs_Human0.77930327
121CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.77595408
122CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.76576782
123TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.75141171
124SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.71539577

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004957_abnormal_blastocyst_morpholog4.52631257
2MP0008057_abnormal_DNA_replication4.21901190
3MP0006292_abnormal_olfactory_placode3.93834101
4MP0003693_abnormal_embryo_hatching3.83475527
5MP0010094_abnormal_chromosome_stability3.32328567
6MP0003111_abnormal_nucleus_morphology3.31490794
7MP0003077_abnormal_cell_cycle3.19514717
8MP0002396_abnormal_hematopoietic_system2.96284034
9MP0003011_delayed_dark_adaptation2.70578632
10MP0005075_abnormal_melanosome_morpholog2.60668826
11MP0004264_abnormal_extraembryonic_tissu2.51093710
12MP0003890_abnormal_embryonic-extraembry2.42435044
13MP0003123_paternal_imprinting2.40375981
14MP0005499_abnormal_olfactory_system2.39461786
15MP0005394_taste/olfaction_phenotype2.39461786
16MP0003941_abnormal_skin_development2.38839955
17MP0008058_abnormal_DNA_repair2.38553373
18MP0008007_abnormal_cellular_replicative2.19445841
19MP0010352_gastrointestinal_tract_polyps2.08744847
20MP0000350_abnormal_cell_proliferation2.07916704
21MP0002254_reproductive_system_inflammat2.07748217
22MP0008932_abnormal_embryonic_tissue2.05264875
23MP0003121_genomic_imprinting2.03892571
24MP0001672_abnormal_embryogenesis/_devel1.99427326
25MP0005380_embryogenesis_phenotype1.99427326
26MP0006035_abnormal_mitochondrial_morpho1.95399894
27MP0001730_embryonic_growth_arrest1.82009047
28MP0003984_embryonic_growth_retardation1.81581897
29MP0002088_abnormal_embryonic_growth/wei1.80165029
30MP0003122_maternal_imprinting1.73899593
31MP0002877_abnormal_melanocyte_morpholog1.61313967
32MP0002332_abnormal_exercise_endurance1.60794788
33MP0000490_abnormal_crypts_of1.53979271
34MP0003786_premature_aging1.53406026
35MP0000313_abnormal_cell_death1.50984284
36MP0009672_abnormal_birth_weight1.50259147
37MP0005257_abnormal_intraocular_pressure1.48361243
38MP0001293_anophthalmia1.47225728
39MP0003315_abnormal_perineum_morphology1.46784628
40MP0002085_abnormal_embryonic_tissue1.45730536
41MP0002653_abnormal_ependyma_morphology1.45703864
42MP0001697_abnormal_embryo_size1.44857830
43MP0002086_abnormal_extraembryonic_tissu1.42959197
44MP0002132_abnormal_respiratory_system1.42639947
45MP0004233_abnormal_muscle_weight1.42145951
46MP0000678_abnormal_parathyroid_gland1.39129291
47MP0010307_abnormal_tumor_latency1.36957159
48MP0005501_abnormal_skin_physiology1.35424622
49MP0002080_prenatal_lethality1.34947967
50MP0008789_abnormal_olfactory_epithelium1.34604181
51MP0009697_abnormal_copulation1.34013762
52MP0000049_abnormal_middle_ear1.33366446
53MP0002277_abnormal_respiratory_mucosa1.33302958
54MP0002084_abnormal_developmental_patter1.33102775
55MP0003938_abnormal_ear_development1.26450962
56MP0004185_abnormal_adipocyte_glucose1.25822789
57MP0001188_hyperpigmentation1.23780145
58MP0010030_abnormal_orbit_morphology1.19632705
59MP0002160_abnormal_reproductive_system1.19471716
60MP0004858_abnormal_nervous_system1.18260845
61MP0002127_abnormal_cardiovascular_syste1.18062103
62MP0004197_abnormal_fetal_growth/weight/1.15504216
63MP0002019_abnormal_tumor_incidence1.14407102
64MP0002796_impaired_skin_barrier1.14022976
65MP0004808_abnormal_hematopoietic_stem1.11125005
66MP0005266_abnormal_metabolism1.07860540
67MP0005408_hypopigmentation1.07156968
68MP0003567_abnormal_fetal_cardiomyocyte1.05506540
69MP0001849_ear_inflammation1.04200365
70MP0002163_abnormal_gland_morphology1.02072731
71MP0003186_abnormal_redox_activity1.01352758
72MP0000750_abnormal_muscle_regeneration1.00879082
73MP0000762_abnormal_tongue_morphology0.99483419
74MP0002932_abnormal_joint_morphology0.99344153
75MP0000358_abnormal_cell_content/0.97622254
76MP0001661_extended_life_span0.97077130
77MP0002722_abnormal_immune_system0.96787287
78MP0002092_abnormal_eye_morphology0.95558575
79MP0002938_white_spotting0.94629891
80MP0002114_abnormal_axial_skeleton0.94127727
81MP0009379_abnormal_foot_pigmentation0.93917071
82MP0004133_heterotaxia0.93536366
83MP0003136_yellow_coat_color0.92937120
84MP0000689_abnormal_spleen_morphology0.92508557
85MP0002751_abnormal_autonomic_nervous0.91775391
86MP0009333_abnormal_splenocyte_physiolog0.90482191
87MP0003119_abnormal_digestive_system0.90038659
88MP0000703_abnormal_thymus_morphology0.89869313
89MP0001881_abnormal_mammary_gland0.89016990
90MP0006036_abnormal_mitochondrial_physio0.88571797
91MP0008770_decreased_survivor_rate0.87827696
92MP0003763_abnormal_thymus_physiology0.87483381
93MP0001346_abnormal_lacrimal_gland0.85940838
94MP0002398_abnormal_bone_marrow0.85730870
95MP0000372_irregular_coat_pigmentation0.84731385
96MP0002233_abnormal_nose_morphology0.84408015
97MP0003718_maternal_effect0.83819659
98MP0000428_abnormal_craniofacial_morphol0.82883649
99MP0000432_abnormal_head_morphology0.82528768
100MP0003806_abnormal_nucleotide_metabolis0.80640666
101MP0001853_heart_inflammation0.80285543
102MP0003705_abnormal_hypodermis_morpholog0.79567924
103MP0001929_abnormal_gametogenesis0.79137458
104MP0000858_altered_metastatic_potential0.76071312
105MP0008877_abnormal_DNA_methylation0.75803026
106MP0002697_abnormal_eye_size0.75736440
107MP0002429_abnormal_blood_cell0.74960623
108MP0005384_cellular_phenotype0.73552203
109MP0003755_abnormal_palate_morphology0.71529525
110MP0000627_abnormal_mammary_gland0.71085240
111MP0002111_abnormal_tail_morphology0.71037976
112MP0000653_abnormal_sex_gland0.70187882
113MP0001286_abnormal_eye_development0.68742896
114MP0005397_hematopoietic_system_phenotyp0.67896807
115MP0001545_abnormal_hematopoietic_system0.67896807
116MP0001348_abnormal_lacrimal_gland0.67785948
117MP0005389_reproductive_system_phenotype0.66249035
118MP0001145_abnormal_male_reproductive0.65701215
119MP0006082_CNS_inflammation0.65390358
120MP0003935_abnormal_craniofacial_develop0.64320184
121MP0005451_abnormal_body_composition0.63085571
122MP0005023_abnormal_wound_healing0.62788498
123MP0005330_cardiomyopathy0.62761466
124MP0005379_endocrine/exocrine_gland_phen0.62593287
125MP0000579_abnormal_nail_morphology0.62429678
126MP0004381_abnormal_hair_follicle0.61854092
127MP0001727_abnormal_embryo_implantation0.61522121
128MP0002970_abnormal_white_adipose0.60509743
129MP0009703_decreased_birth_body0.59704981
130MP0002210_abnormal_sex_determination0.58484819
131MP0003937_abnormal_limbs/digits/tail_de0.58179788
132MP0000716_abnormal_immune_system0.58091103
133MP0006072_abnormal_retinal_apoptosis0.56694589
134MP0002060_abnormal_skin_morphology0.56012415
135MP0003699_abnormal_female_reproductive0.55452939
136MP0003943_abnormal_hepatobiliary_system0.55115774
137MP0005395_other_phenotype0.54792121
138MP0001919_abnormal_reproductive_system0.53394950
139MP0005621_abnormal_cell_physiology0.52876135
140MP0010771_integument_phenotype0.51857174
141MP0001873_stomach_inflammation0.49904593
142MP0002161_abnormal_fertility/fecundity0.48466250
143MP0002269_muscular_atrophy0.48412566
144MP0001119_abnormal_female_reproductive0.48174348
145MP0002177_abnormal_outer_ear0.47912314
146MP0005171_absent_coat_pigmentation0.46758869
147MP0005076_abnormal_cell_differentiation0.46309302

Predicted human phenotypes

RankGene SetZ-score
1Bilateral microphthalmos (HP:0007633)5.00890945
2Multiple enchondromatosis (HP:0005701)4.63350306
3Acute necrotizing encephalopathy (HP:0006965)4.26080094
4Hypochromic microcytic anemia (HP:0004840)4.05309108
5Abnormal mitochondria in muscle tissue (HP:0008316)4.00823459
6Rib fusion (HP:0000902)3.93468857
7Chromosomal breakage induced by crosslinking agents (HP:0003221)3.92566317
8Increased hepatocellular lipid droplets (HP:0006565)3.86442118
9Acute encephalopathy (HP:0006846)3.84379352
10Chromsome breakage (HP:0040012)3.75277338
11Ependymoma (HP:0002888)3.72455837
12Increased CSF lactate (HP:0002490)3.58725344
13Mitochondrial inheritance (HP:0001427)3.57759744
14Abnormality of cells of the erythroid lineage (HP:0012130)3.54940045
15Aplastic anemia (HP:0001915)3.52687004
16Abnormal number of erythroid precursors (HP:0012131)3.40830785
17Lipid accumulation in hepatocytes (HP:0006561)3.40687223
18Progressive macrocephaly (HP:0004481)3.34233618
19Rhabdomyosarcoma (HP:0002859)3.32145533
20Trismus (HP:0000211)3.25374253
21Abnormal lung lobation (HP:0002101)3.19384979
22Cerebral edema (HP:0002181)3.18777151
23Nephroblastoma (Wilms tumor) (HP:0002667)3.06979915
24Renal Fanconi syndrome (HP:0001994)3.06181311
25Rectovaginal fistula (HP:0000143)3.05584731
26Rectal fistula (HP:0100590)3.05584731
27Reduced antithrombin III activity (HP:0001976)3.04174480
28Neoplasm of striated muscle (HP:0009728)3.03293689
29Increased intramyocellular lipid droplets (HP:0012240)3.00293217
30Increased serum lactate (HP:0002151)2.99938165
31Birth length less than 3rd percentile (HP:0003561)2.98306391
32Meckel diverticulum (HP:0002245)2.97778990
33Supernumerary spleens (HP:0009799)2.94542950
34Hepatoblastoma (HP:0002884)2.92084082
35Hepatocellular necrosis (HP:0001404)2.91779124
36Glossoptosis (HP:0000162)2.88497607
37Embryonal renal neoplasm (HP:0011794)2.86018003
38Reticulocytopenia (HP:0001896)2.84605107
39Oral leukoplakia (HP:0002745)2.83324342
40Testicular atrophy (HP:0000029)2.83308073
41Decreased activity of mitochondrial respiratory chain (HP:0008972)2.83257315
42Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.83257315
43Microvesicular hepatic steatosis (HP:0001414)2.80909398
44Microretrognathia (HP:0000308)2.78570864
45Abnormality of the preputium (HP:0100587)2.77894810
46Abnormality of the ileum (HP:0001549)2.77814290
47Partial duplication of thumb phalanx (HP:0009944)2.76302897
48Impulsivity (HP:0100710)2.75439836
49Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.72444865
50Exercise intolerance (HP:0003546)2.70569385
51Intestinal fistula (HP:0100819)2.70065962
523-Methylglutaconic aciduria (HP:0003535)2.68493090
53Aplasia/Hypoplasia of the uvula (HP:0010293)2.67837220
54Abnormality of the lower motor neuron (HP:0002366)2.65093713
55Myelodysplasia (HP:0002863)2.59676424
56Abnormality of methionine metabolism (HP:0010901)2.59300783
57Aplasia/Hypoplasia of the sacrum (HP:0008517)2.59198961
58Progressive muscle weakness (HP:0003323)2.58251169
59Aplasia/hypoplasia of the humerus (HP:0006507)2.57735386
60Lactic acidosis (HP:0003128)2.55741553
61Rough bone trabeculation (HP:0100670)2.54632065
62Pendular nystagmus (HP:0012043)2.54358554
63Hepatic necrosis (HP:0002605)2.53111470
64Respiratory difficulties (HP:0002880)2.50782513
65Atrophy/Degeneration involving motor neurons (HP:0007373)2.50757880
66Squamous cell carcinoma (HP:0002860)2.50433313
67Vaginal fistula (HP:0004320)2.50321485
68Fused cervical vertebrae (HP:0002949)2.49782879
69Medulloblastoma (HP:0002885)2.47991281
70Type I transferrin isoform profile (HP:0003642)2.47955510
71Sensory axonal neuropathy (HP:0003390)2.47736242
72Partial duplication of the phalanx of hand (HP:0009999)2.47303344
73Selective tooth agenesis (HP:0001592)2.46604188
74Breast hypoplasia (HP:0003187)2.45272681
75Premature ovarian failure (HP:0008209)2.44565425
76Absent thumb (HP:0009777)2.44041618
77Horseshoe kidney (HP:0000085)2.43944479
78Tongue fasciculations (HP:0001308)2.43226146
79Ragged-red muscle fibers (HP:0003200)2.43127015
80Preauricular skin tag (HP:0000384)2.42477242
81Hypochromic anemia (HP:0001931)2.41857442
82Pallor (HP:0000980)2.41549517
83Increased muscle lipid content (HP:0009058)2.39310130
84Pancytopenia (HP:0001876)2.36696677
85Leukodystrophy (HP:0002415)2.36050317
86Anomalous pulmonary venous return (HP:0010772)2.35361447
87Amyotrophic lateral sclerosis (HP:0007354)2.34016931
88Sparse eyelashes (HP:0000653)2.32571270
89Small intestinal stenosis (HP:0012848)2.30161863
90Duodenal stenosis (HP:0100867)2.30161863
91Abnormality of the anterior horn cell (HP:0006802)2.29440393
92Degeneration of anterior horn cells (HP:0002398)2.29440393
93Absent radius (HP:0003974)2.29207088
94Aplasia/Hypoplasia of the sternum (HP:0006714)2.27561123
95Abnormality of placental membranes (HP:0011409)2.25998663
96Amniotic constriction ring (HP:0009775)2.25998663
97Increased serum pyruvate (HP:0003542)2.25267088
98Abnormality of glycolysis (HP:0004366)2.25267088
99Short humerus (HP:0005792)2.25189100
100Atresia of the external auditory canal (HP:0000413)2.23898476
101Abnormality of the astrocytes (HP:0100707)2.22970786
102Astrocytoma (HP:0009592)2.22970786
103Megaloblastic anemia (HP:0001889)2.19912349
104Muscle fibrillation (HP:0010546)2.17392268
105Abnormality of chromosome stability (HP:0003220)2.17332877
106Abnormal trabecular bone morphology (HP:0100671)2.13496674
107Bone marrow hypocellularity (HP:0005528)2.13452278
108Bifid tongue (HP:0010297)2.12689404
109Respiratory failure (HP:0002878)2.12637985
110Aplasia/Hypoplasia of the fovea (HP:0008060)2.11423120
111Hypoplasia of the fovea (HP:0007750)2.11423120
112Sloping forehead (HP:0000340)2.10974924
113Absent forearm bone (HP:0003953)2.10703861
114Aplasia involving forearm bones (HP:0009822)2.10703861
115Carpal bone hypoplasia (HP:0001498)2.07692793
116Cleft eyelid (HP:0000625)2.07418868
117Skin tags (HP:0010609)2.07007502
118Abnormality of the phalanges of the hallux (HP:0010057)2.06687365
119Homocystinuria (HP:0002156)2.05446963
120Abnormality of homocysteine metabolism (HP:0010919)2.05446963
121Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.04546411
122Progressive external ophthalmoplegia (HP:0000590)2.03874724
123Patellar aplasia (HP:0006443)2.03685109
124Macrocytic anemia (HP:0001972)2.02131778
125Facial cleft (HP:0002006)2.01289163
126Triphalangeal thumb (HP:0001199)2.00267754
127Abnormality of the salivary glands (HP:0010286)1.99415781
128Secondary amenorrhea (HP:0000869)1.98387433
129Abnormal number of incisors (HP:0011064)1.97914999
130Cerebral hypomyelination (HP:0006808)1.97350967
131Nasolacrimal duct obstruction (HP:0000579)1.96758312
132Abnormal cartilage morphology (HP:0002763)1.96495712
133Abnormality of the pulmonary veins (HP:0011718)1.95889995
134Increased nuchal translucency (HP:0010880)1.95560013
135Ectopic kidney (HP:0000086)1.95087065
136Colon cancer (HP:0003003)1.94884641
137Cellular immunodeficiency (HP:0005374)1.94572272
138Duplication of thumb phalanx (HP:0009942)1.93504561
139Abnormality of alanine metabolism (HP:0010916)1.93291035
140Hyperalaninemia (HP:0003348)1.93291035
141Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.93291035
142Missing ribs (HP:0000921)1.93039568
143Hypoplasia of the pons (HP:0012110)1.92684172
144Horizontal nystagmus (HP:0000666)1.92447685
145Short 5th finger (HP:0009237)1.92082957
146Exertional dyspnea (HP:0002875)1.88332247
147Abnormal protein N-linked glycosylation (HP:0012347)1.87762178
148Abnormal protein glycosylation (HP:0012346)1.87762178
149Abnormal glycosylation (HP:0012345)1.87762178
150Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.87762178
151Premature graying of hair (HP:0002216)1.85972473
152Abnormality of the pons (HP:0007361)1.81828912
153Urethral obstruction (HP:0000796)1.80963803
154Lethargy (HP:0001254)1.77358635
155Short thumb (HP:0009778)1.73659302

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK126.35197568
2VRK23.75442893
3PBK3.63311741
4GRK53.57052351
5GRK63.37653331
6ERN12.98988554
7TTK2.94852203
8BUB12.93321688
9CDC72.88350727
10WEE12.80417485
11ADRBK22.47391222
12NME22.32033441
13STK102.25852228
14EIF2AK12.24942328
15CSF1R2.18281227
16GRK12.15675708
17CDK72.14055720
18SRPK12.06480188
19PLK11.87841752
20GRK71.78731253
21NEK21.72804742
22MATK1.62894988
23PDK21.62374928
24TGFBR21.58851378
25MKNK11.57853183
26CHEK21.55704927
27MOS1.48637689
28TAF11.45172844
29TSSK61.44943616
30MKNK21.35337829
31SMG11.34867311
32PAK41.34280046
33MAPK71.34183122
34EIF2AK21.31961231
35EIF2AK31.26968948
36NUAK11.25221421
37AURKB1.22441209
38CHEK11.20219761
39VRK11.19384760
40STK161.18659125
41RPS6KB21.18132391
42TESK21.14849098
43NEK11.09189431
44DYRK31.07724953
45AURKA1.06646998
46TRIM281.05151616
47PRKG21.01390830
48ATR0.99297559
49TYRO30.98944199
50NME10.97609985
51EPHA20.95731523
52PIM20.93844923
53BRSK20.93007828
54PLK40.90741175
55ALK0.89850306
56IRAK30.89238381
57MST1R0.88360222
58CDK40.85270929
59CDK80.84786561
60CAMK40.82762250
61DAPK10.81372039
62CDK20.79905632
63MAP2K60.78394776
64PLK30.75055926
65ADRBK10.74782076
66AKT20.74286229
67TLK10.73542742
68AKT30.72671641
69ATM0.70109504
70ERBB40.65520755
71MAP3K80.65447545
72TAOK20.64301845
73CLK10.63796360
74PAK10.60660580
75MST40.60379937
76CSNK2A20.59658534
77BCKDK0.59538312
78PRKCI0.58722959
79ACVR1B0.58459470
80CSNK1E0.55755607
81RPS6KA40.55333673
82ABL20.55190825
83CDK190.54753720
84PIM10.53201182
85PASK0.52929379
86LATS20.51920256
87HIPK20.51608471
88BMPR1B0.51486735
89MARK20.50911370
90DMPK0.50666904
91MAP4K10.50651053
92CSNK2A10.50639849
93WNK10.50588882
94STK40.49513166
95CDK10.49156639
96BRSK10.47111589
97WNK40.46930920
98MAP3K120.46697247
99IKBKB0.45518577
100PRKDC0.44069180
101STK30.41026595
102CDK90.40528940
103KDR0.40430185
104CCNB10.39639585
105ILK0.39208733
106TGFBR10.38862677
107BRD40.38702009
108MAP3K100.37907782
109MAP2K30.36160065
110CSNK1G10.34325509
111MAPK120.33705785
112MTOR0.32708664
113DYRK20.31450622
114CDK30.30961417
115KIT0.30373149
116BRAF0.29582842
117PNCK0.27914799
118TNIK0.26167476
119ZAK0.25644861
120MAPK140.24686217
121CSNK1G30.24192261
122MAP2K40.24015279
123PAK20.23434201
124MAP3K110.23082523
125GSK3B0.22347824
126CSK0.22024232
127MAPK40.21659736
128CDK11A0.21146287
129INSRR0.21033656
130YES10.20918129
131RPS6KA50.20790190
132LATS10.20263696
133SCYL20.20234901
134LRRK20.19830945

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.97931904
2Ribosome_Homo sapiens_hsa030104.51476989
3DNA replication_Homo sapiens_hsa030304.27758456
4Mismatch repair_Homo sapiens_hsa034303.51927190
5RNA polymerase_Homo sapiens_hsa030203.22686550
6Spliceosome_Homo sapiens_hsa030403.16611326
7RNA transport_Homo sapiens_hsa030133.13529393
8Proteasome_Homo sapiens_hsa030502.95452699
9Homologous recombination_Homo sapiens_hsa034402.89305615
10Vitamin B6 metabolism_Homo sapiens_hsa007502.68987802
11One carbon pool by folate_Homo sapiens_hsa006702.55955572
12Base excision repair_Homo sapiens_hsa034102.46865386
13Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.43990916
14Nucleotide excision repair_Homo sapiens_hsa034202.35800163
15Pyrimidine metabolism_Homo sapiens_hsa002402.28957732
16Fanconi anemia pathway_Homo sapiens_hsa034602.17648310
17Cell cycle_Homo sapiens_hsa041102.15812756
18RNA degradation_Homo sapiens_hsa030182.11477498
19Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.99040023
20Basal transcription factors_Homo sapiens_hsa030221.95084289
21mRNA surveillance pathway_Homo sapiens_hsa030151.77352883
22Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.64367654
23Fructose and mannose metabolism_Homo sapiens_hsa000511.64321759
24Non-homologous end-joining_Homo sapiens_hsa034501.61793672
25Pyruvate metabolism_Homo sapiens_hsa006201.30954058
26p53 signaling pathway_Homo sapiens_hsa041151.30040535
27Galactose metabolism_Homo sapiens_hsa000521.27806728
28Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.21266853
29Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.18697238
30Thyroid cancer_Homo sapiens_hsa052161.17998569
31Purine metabolism_Homo sapiens_hsa002301.15379215
32Arachidonic acid metabolism_Homo sapiens_hsa005901.14296529
33Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.05655998
34Sulfur relay system_Homo sapiens_hsa041220.97378549
35Folate biosynthesis_Homo sapiens_hsa007900.97183151
36Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.93888824
37Herpes simplex infection_Homo sapiens_hsa051680.88051609
38Cysteine and methionine metabolism_Homo sapiens_hsa002700.86845915
39Primary immunodeficiency_Homo sapiens_hsa053400.78950079
40Pentose phosphate pathway_Homo sapiens_hsa000300.77316816
41Epstein-Barr virus infection_Homo sapiens_hsa051690.77199499
42Huntingtons disease_Homo sapiens_hsa050160.74369836
43Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.70821346
44Linoleic acid metabolism_Homo sapiens_hsa005910.70572597
45Parkinsons disease_Homo sapiens_hsa050120.67518024
46Transcriptional misregulation in cancer_Homo sapiens_hsa052020.67127108
47Propanoate metabolism_Homo sapiens_hsa006400.64430520
48Cardiac muscle contraction_Homo sapiens_hsa042600.63170622
49Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.62612469
50Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.59522554
51Antigen processing and presentation_Homo sapiens_hsa046120.59391725
52Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.57879149
53Fatty acid elongation_Homo sapiens_hsa000620.56800452
54Biosynthesis of amino acids_Homo sapiens_hsa012300.55539763
55Cyanoamino acid metabolism_Homo sapiens_hsa004600.55423328
56Oxidative phosphorylation_Homo sapiens_hsa001900.53642485
57Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.51891597
58RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.49299835
59Viral carcinogenesis_Homo sapiens_hsa052030.49285856
60Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.49225592
61HTLV-I infection_Homo sapiens_hsa051660.48956315
62alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.48233761
63N-Glycan biosynthesis_Homo sapiens_hsa005100.46881762
64Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.45191534
65MicroRNAs in cancer_Homo sapiens_hsa052060.45186965
66Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.44170901
67Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.43641246
68Oocyte meiosis_Homo sapiens_hsa041140.43497199
69Arginine and proline metabolism_Homo sapiens_hsa003300.42874054
70Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.41690264
71Apoptosis_Homo sapiens_hsa042100.41179273
72Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.40706338
73Lysine degradation_Homo sapiens_hsa003100.40101472
74Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.39589806
75Acute myeloid leukemia_Homo sapiens_hsa052210.35917632
76Carbon metabolism_Homo sapiens_hsa012000.35787624
77Drug metabolism - other enzymes_Homo sapiens_hsa009830.35214123
78Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.34318503
79Pathways in cancer_Homo sapiens_hsa052000.33874800
80Metabolic pathways_Homo sapiens_hsa011000.33802253
81Sulfur metabolism_Homo sapiens_hsa009200.32622465
82Vitamin digestion and absorption_Homo sapiens_hsa049770.29171837
83NF-kappa B signaling pathway_Homo sapiens_hsa040640.28784687
84Protein export_Homo sapiens_hsa030600.28033287
85Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.27934241
86Basal cell carcinoma_Homo sapiens_hsa052170.27455953
87mTOR signaling pathway_Homo sapiens_hsa041500.27403496
88Glutathione metabolism_Homo sapiens_hsa004800.27229755
89Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.27222856
90Pentose and glucuronate interconversions_Homo sapiens_hsa000400.25904428
91Systemic lupus erythematosus_Homo sapiens_hsa053220.24451505
92Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.23623200
93Selenocompound metabolism_Homo sapiens_hsa004500.23091864
94Small cell lung cancer_Homo sapiens_hsa052220.23032575
95Central carbon metabolism in cancer_Homo sapiens_hsa052300.21696647
96Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.20997341
97Bladder cancer_Homo sapiens_hsa052190.20792685
98Alzheimers disease_Homo sapiens_hsa050100.20768397
99Intestinal immune network for IgA production_Homo sapiens_hsa046720.20163444
100Other glycan degradation_Homo sapiens_hsa005110.20100002
101Legionellosis_Homo sapiens_hsa051340.20055699
102Steroid biosynthesis_Homo sapiens_hsa001000.19823981
103Hematopoietic cell lineage_Homo sapiens_hsa046400.17853220
104Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.16370275
105Colorectal cancer_Homo sapiens_hsa052100.14014654
106Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.13772554
107Wnt signaling pathway_Homo sapiens_hsa043100.13548619
108Regulation of actin cytoskeleton_Homo sapiens_hsa048100.13254411
109beta-Alanine metabolism_Homo sapiens_hsa004100.12912035
110Notch signaling pathway_Homo sapiens_hsa043300.12464528
111Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.12176092
112Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.11816306
113Influenza A_Homo sapiens_hsa051640.11194366
114Non-small cell lung cancer_Homo sapiens_hsa052230.10807843
115Hippo signaling pathway_Homo sapiens_hsa043900.10354772
1162-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.10201308
117TGF-beta signaling pathway_Homo sapiens_hsa043500.10017665
118Fatty acid metabolism_Homo sapiens_hsa012120.09910692
119Measles_Homo sapiens_hsa051620.09879159
120Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.08965559
121Tyrosine metabolism_Homo sapiens_hsa003500.07384334
122HIF-1 signaling pathway_Homo sapiens_hsa040660.07054537
123Arginine biosynthesis_Homo sapiens_hsa002200.05884557
124Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.04959667
125Peroxisome_Homo sapiens_hsa041460.03099063
126Fatty acid degradation_Homo sapiens_hsa000710.00065888
127Shigellosis_Homo sapiens_hsa05131-0.0797630
128Other types of O-glycan biosynthesis_Homo sapiens_hsa00514-0.0707652
129Tight junction_Homo sapiens_hsa04530-0.0343904
130Adherens junction_Homo sapiens_hsa04520-0.0309358
131Melanoma_Homo sapiens_hsa05218-0.0273877
132Phenylalanine metabolism_Homo sapiens_hsa00360-0.0129588

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