GPC2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)8.50643163
2nucleobase catabolic process (GO:0046113)6.39097084
3cell migration in hindbrain (GO:0021535)6.34371596
4behavioral response to nicotine (GO:0035095)5.69430615
5axonal fasciculation (GO:0007413)5.38676021
6central nervous system projection neuron axonogenesis (GO:0021952)5.15949166
7layer formation in cerebral cortex (GO:0021819)5.05101306
8postsynaptic membrane organization (GO:0001941)4.72941856
9neuron recognition (GO:0008038)4.54125581
10glial cell proliferation (GO:0014009)4.46117675
11nucleosome disassembly (GO:0006337)4.43595741
12protein-DNA complex disassembly (GO:0032986)4.43595741
13regulation of inhibitory postsynaptic membrane potential (GO:0060080)4.36125081
14establishment of mitochondrion localization (GO:0051654)4.31187322
15dendritic spine morphogenesis (GO:0060997)4.12475294
16dendrite morphogenesis (GO:0048813)4.07250828
17presynaptic membrane organization (GO:0097090)4.01556761
18cranial nerve morphogenesis (GO:0021602)4.00464721
19negative regulation of axon guidance (GO:1902668)4.00345158
20response to pheromone (GO:0019236)3.98357289
21negative regulation of axon extension involved in axon guidance (GO:0048843)3.96288213
22presynaptic membrane assembly (GO:0097105)3.95497676
23planar cell polarity pathway involved in neural tube closure (GO:0090179)3.90495078
24negative regulation of catenin import into nucleus (GO:0035414)3.88871245
25negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.87864923
26mitochondrion transport along microtubule (GO:0047497)3.83516216
27establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.83516216
28protein localization to synapse (GO:0035418)3.76609003
29central nervous system neuron axonogenesis (GO:0021955)3.76108164
30regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.73162472
31forebrain neuron differentiation (GO:0021879)3.66781481
32neurofilament cytoskeleton organization (GO:0060052)3.65408401
33establishment of nucleus localization (GO:0040023)3.60297731
34semaphorin-plexin signaling pathway (GO:0071526)3.59838287
35axon extension (GO:0048675)3.58294992
36spinal cord development (GO:0021510)3.55808125
37negative regulation of RNA splicing (GO:0033119)3.51881988
38limb bud formation (GO:0060174)3.50679424
39negative regulation of microtubule polymerization (GO:0031115)3.49744180
40hippocampus development (GO:0021766)3.47615955
41positive regulation of RNA splicing (GO:0033120)3.42770044
42negative regulation of axon extension (GO:0030517)3.42046632
43gastrulation with mouth forming second (GO:0001702)3.41967857
44head development (GO:0060322)3.41197540
45auditory behavior (GO:0031223)3.40798408
46neuron migration (GO:0001764)3.39568367
47cerebral cortex radially oriented cell migration (GO:0021799)3.38470404
48lateral sprouting from an epithelium (GO:0060601)3.37945986
49locomotory exploration behavior (GO:0035641)3.33726087
50nonmotile primary cilium assembly (GO:0035058)3.27683041
51peptidyl-arginine methylation (GO:0018216)3.27560095
52peptidyl-arginine N-methylation (GO:0035246)3.27560095
53regulation of short-term neuronal synaptic plasticity (GO:0048172)3.26386809
54negative regulation of mRNA processing (GO:0050686)3.24952103
55mRNA splice site selection (GO:0006376)3.24752048
56transmission of nerve impulse (GO:0019226)3.23191435
57cerebellum development (GO:0021549)3.21702842
58regulation of axon guidance (GO:1902667)3.21678938
59neuron projection extension (GO:1990138)3.16819637
60synapse assembly (GO:0007416)3.16095246
61vocalization behavior (GO:0071625)3.16014802
62neuromuscular synaptic transmission (GO:0007274)3.13650155
63synaptic transmission, cholinergic (GO:0007271)3.13372127
64neuron cell-cell adhesion (GO:0007158)3.12704108
65generation of neurons (GO:0048699)3.12627705
66regulation of NFAT protein import into nucleus (GO:0051532)3.11670587
67ganglion development (GO:0061548)3.11381445
68cell proliferation in forebrain (GO:0021846)3.10500477
69regulation of axon extension involved in axon guidance (GO:0048841)3.08755942
70proximal/distal pattern formation (GO:0009954)3.07666472
71protein polyglutamylation (GO:0018095)3.06862710
72regulation of mRNA splicing, via spliceosome (GO:0048024)3.06600792
73exploration behavior (GO:0035640)3.06377372
74regulation of alternative mRNA splicing, via spliceosome (GO:0000381)3.01941102
75peptidyl-arginine omega-N-methylation (GO:0035247)3.01451543
76synaptic transmission, glutamatergic (GO:0035249)3.00008592
77positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.98416859
78regulation of synapse structural plasticity (GO:0051823)2.97548146
79dendrite development (GO:0016358)2.96380022
80cerebral cortex neuron differentiation (GO:0021895)2.95400396
81olfactory bulb development (GO:0021772)2.94644564
82negative regulation of oligodendrocyte differentiation (GO:0048715)2.94582030
83mechanosensory behavior (GO:0007638)2.94378140
84cochlea morphogenesis (GO:0090103)2.93909718
85neuron projection extension involved in neuron projection guidance (GO:1902284)2.93432058
86axon extension involved in axon guidance (GO:0048846)2.93432058
87regulation of axon extension (GO:0030516)2.92673064
88negative regulation of axonogenesis (GO:0050771)2.92642972
89neuronal ion channel clustering (GO:0045161)2.91897478
90spinal cord association neuron differentiation (GO:0021527)2.91094251
91establishment of tissue polarity (GO:0007164)2.90644260
92establishment of planar polarity (GO:0001736)2.90644260
93ionotropic glutamate receptor signaling pathway (GO:0035235)2.90551894
94G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.90016972
95positive regulation of gastrulation (GO:2000543)2.88626453
96urogenital system development (GO:0001655)2.87584604
97positive regulation of filopodium assembly (GO:0051491)2.86539442
98RNA localization (GO:0006403)2.86424788
99ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.86037702
100neuronal stem cell maintenance (GO:0097150)2.85726835
101positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.85566653
102neurotransmitter-gated ion channel clustering (GO:0072578)2.83616220
103cell differentiation in spinal cord (GO:0021515)2.83154829
104regulation of neuron migration (GO:2001222)2.83144376
105positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)2.82404872
106adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.82042329
107dosage compensation (GO:0007549)2.82012638
108pre-miRNA processing (GO:0031054)2.81663948
109substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.80180994
110substrate-independent telencephalic tangential migration (GO:0021826)2.80180994
111spliceosomal tri-snRNP complex assembly (GO:0000244)2.78990135
112kidney morphogenesis (GO:0060993)2.78310865
113facial nerve structural organization (GO:0021612)2.77834578
114calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.77446247
115lens morphogenesis in camera-type eye (GO:0002089)2.76008612
116nucleus localization (GO:0051647)2.74758675
117positive regulation of synapse assembly (GO:0051965)2.74262234
118short-term memory (GO:0007614)2.73480776
119regulation of extent of cell growth (GO:0061387)2.72984153
120regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.71061797
121synaptic vesicle maturation (GO:0016188)2.70109519
122epithelial cilium movement (GO:0003351)2.69599199
123stress granule assembly (GO:0034063)2.67795121
124regulation of microtubule-based movement (GO:0060632)2.67414831
125glutamate receptor signaling pathway (GO:0007215)2.65977041
126hippo signaling (GO:0035329)2.62248991
127Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.61381209
128cerebellar Purkinje cell differentiation (GO:0021702)2.61055328
129somite development (GO:0061053)2.60108910
130positive regulation of synapse maturation (GO:0090129)2.59797442
131response to auditory stimulus (GO:0010996)2.58501852
132behavioral response to ethanol (GO:0048149)2.58374213
133regulation of RNA splicing (GO:0043484)2.57312158
134retina layer formation (GO:0010842)2.56824150
135regulation of establishment of planar polarity (GO:0090175)2.56444574
136adult walking behavior (GO:0007628)2.56406648
137hindbrain development (GO:0030902)2.56336487
138regulation of respiratory system process (GO:0044065)2.56292129
139retinal ganglion cell axon guidance (GO:0031290)2.56222280
140regulation of glutamate receptor signaling pathway (GO:1900449)2.55573641
141synapse organization (GO:0050808)2.55551640
142membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.55138351
143positive regulation of axon extension (GO:0045773)2.54763539
144polarized epithelial cell differentiation (GO:0030859)2.53802796
145negative regulation of mRNA metabolic process (GO:1903312)2.53696648
146gamma-aminobutyric acid transport (GO:0015812)2.53127584
147motor neuron axon guidance (GO:0008045)2.52540673
148sympathetic nervous system development (GO:0048485)2.51953325
149axonogenesis (GO:0007409)2.51934180
150ephrin receptor signaling pathway (GO:0048013)2.50946369
151camera-type eye morphogenesis (GO:0048593)2.50575705
152positive regulation of dendrite morphogenesis (GO:0050775)2.49787835
153regulation of cilium movement (GO:0003352)2.49498873
154regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.48554380
155cell differentiation in hindbrain (GO:0021533)2.47158751
156epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.46893676
157positive regulation of dendritic spine morphogenesis (GO:0061003)2.46838774
158dopaminergic neuron differentiation (GO:0071542)2.46683185
159neuron-neuron synaptic transmission (GO:0007270)2.46079968
160negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.45750927

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.07670944
2* NR4A2_19515692_ChIP-ChIP_MN9D_Mouse3.24658757
3EZH2_27304074_Chip-Seq_ESCs_Mouse2.96428379
4* ZFP281_18757296_ChIP-ChIP_E14_Mouse2.83318046
5EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.78271533
6TP63_19390658_ChIP-ChIP_HaCaT_Human2.77405993
7EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.61901761
8CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.52123411
9ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.49368505
10JARID2_20064375_ChIP-Seq_MESCs_Mouse2.37445775
11STAT6_21828071_ChIP-Seq_BEAS2B_Human2.32909266
12CBX2_27304074_Chip-Seq_ESCs_Mouse2.30197127
13EZH2_18974828_ChIP-Seq_MESCs_Mouse2.28033169
14RNF2_18974828_ChIP-Seq_MESCs_Mouse2.28033169
15RNF2_27304074_Chip-Seq_ESCs_Mouse2.25762248
16OLIG2_26023283_ChIP-Seq_AINV15_Mouse2.24559339
17ZFP281_27345836_Chip-Seq_ESCs_Mouse2.22458301
18EZH2_27294783_Chip-Seq_ESCs_Mouse2.21636815
19WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.21086047
20RING1B_27294783_Chip-Seq_NPCs_Mouse2.17161638
21PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.15118114
22JARID2_20075857_ChIP-Seq_MESCs_Mouse2.09734248
23SUZ12_27294783_Chip-Seq_ESCs_Mouse2.08371516
24ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.05845416
25GBX2_23144817_ChIP-Seq_PC3_Human2.05095982
26GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.02668478
27RBPJ_22232070_ChIP-Seq_NCS_Mouse2.00830302
28SALL1_21062744_ChIP-ChIP_HESCs_Human2.00161495
29RING1B_27294783_Chip-Seq_ESCs_Mouse1.94178356
30SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.90506518
31TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.90467933
32* EED_16625203_ChIP-ChIP_MESCs_Mouse1.89074351
33TP53_20018659_ChIP-ChIP_R1E_Mouse1.89071863
34HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.85072413
35SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.84723043
36SOX2_18555785_ChIP-Seq_MESCs_Mouse1.83524798
37RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.83290985
38TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.77439171
39SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.76390529
40SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.75292082
41KDM2B_26808549_Chip-Seq_K562_Human1.71733661
42CTBP1_25329375_ChIP-Seq_LNCAP_Human1.71289173
43SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.71030474
44SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.70637535
45BMI1_23680149_ChIP-Seq_NPCS_Mouse1.66664816
46FOXM1_23109430_ChIP-Seq_U2OS_Human1.66051983
47RNF2_27304074_Chip-Seq_NSC_Mouse1.65329377
48POU5F1_16153702_ChIP-ChIP_HESCs_Human1.64539291
49HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.62912980
50DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.62652982
51ERG_21242973_ChIP-ChIP_JURKAT_Human1.60059396
52REST_21632747_ChIP-Seq_MESCs_Mouse1.58976727
53SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.56839909
54ZFP57_27257070_Chip-Seq_ESCs_Mouse1.53017173
55KDM2B_26808549_Chip-Seq_JURKAT_Human1.51859704
56IKZF1_21737484_ChIP-ChIP_HCT116_Human1.51630181
57ISL1_27105846_Chip-Seq_CPCs_Mouse1.50111952
58SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.46696992
59SOX2_16153702_ChIP-ChIP_HESCs_Human1.46567935
60IGF1R_20145208_ChIP-Seq_DFB_Human1.44040396
61MYC_22102868_ChIP-Seq_BL_Human1.41282146
62VDR_22108803_ChIP-Seq_LS180_Human1.39691031
63KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.37746391
64PKCTHETA_26484144_Chip-Seq_BREAST_Human1.36095374
65KDM2B_26808549_Chip-Seq_SUP-B15_Human1.35033352
66KDM2B_26808549_Chip-Seq_DND41_Human1.34828563
67REST_18959480_ChIP-ChIP_MESCs_Mouse1.31748880
68SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.28600880
69GATA1_26923725_Chip-Seq_HPCs_Mouse1.28413310
70SOX3_22085726_ChIP-Seq_NPCs_Mouse1.26115488
71ZNF274_21170338_ChIP-Seq_K562_Hela1.25527721
72TAF15_26573619_Chip-Seq_HEK293_Human1.24663630
73TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.24376775
74MTF2_20144788_ChIP-Seq_MESCs_Mouse1.23948333
75CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.23023663
76RARB_27405468_Chip-Seq_BRAIN_Mouse1.22545940
77NFIB_24661679_ChIP-Seq_LUNG_Mouse1.20792993
78NANOG_21062744_ChIP-ChIP_HESCs_Human1.18542914
79* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.17496016
80P300_19829295_ChIP-Seq_ESCs_Human1.14627130
81FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.14288183
82KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.13838505
83TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13811894
84AR_21572438_ChIP-Seq_LNCaP_Human1.11155629
85POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.10619562
86FUS_26573619_Chip-Seq_HEK293_Human1.10361362
87RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.09528756
88DROSHA_22980978_ChIP-Seq_HELA_Human1.07561712
89SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.07404544
90KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.06919768
91DNAJC2_21179169_ChIP-ChIP_NT2_Human1.05980356
92KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.05848477
93ETV2_25802403_ChIP-Seq_MESCs_Mouse1.05568769
94TOP2B_26459242_ChIP-Seq_MCF-7_Human1.05525997
95SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.05448843
96SMAD3_21741376_ChIP-Seq_ESCs_Human1.05046142
97TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.04056768
98CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.03844187
99SMAD4_21799915_ChIP-Seq_A2780_Human1.01330736
100P53_22127205_ChIP-Seq_FIBROBLAST_Human1.01304567
101CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.01002526
102DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.00929191
103SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.00595461
104MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.99963888
105WT1_25993318_ChIP-Seq_PODOCYTE_Human0.99479843
106GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.99243546
107CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98765254
108PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.98656290
109NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.98208052
110POU3F1_26484290_ChIP-Seq_ESCss_Mouse0.97670971
111YAP1_20516196_ChIP-Seq_MESCs_Mouse0.97594356
112CREB1_26743006_Chip-Seq_LNCaP_Human0.97509336
113CTCF_27219007_Chip-Seq_Bcells_Human0.97460301
114SMAD3_21741376_ChIP-Seq_EPCs_Human0.97280669
115P300_27058665_Chip-Seq_ZR-75-30cells_Human0.95159723
116SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.94978773
117UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.94894623
118IRF1_19129219_ChIP-ChIP_H3396_Human0.94545572
119CIITA_25753668_ChIP-Seq_RAJI_Human0.94265177
120RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.93409489
121AR_19668381_ChIP-Seq_PC3_Human0.93032579
122CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.92251875
123POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.92240196
124TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.92240196
125KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.92013589
126MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.91017975
127STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.90827431
128AR_25329375_ChIP-Seq_VCAP_Human0.90718412
129TCF7_22412390_ChIP-Seq_EML_Mouse0.90600637
130ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.89608956
131CTBP2_25329375_ChIP-Seq_LNCAP_Human0.89591433
132MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.89212664
133IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.87869426
134CBP_20019798_ChIP-Seq_JUKART_Human0.87869426
135RUNX2_22187159_ChIP-Seq_PCA_Human0.87318315
136UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.86906208
137WDR5_24793694_ChIP-Seq_LNCAP_Human0.86754667
138FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.85410974
139KLF5_20875108_ChIP-Seq_MESCs_Mouse0.84345617
140MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.83759407
141STAT3_23295773_ChIP-Seq_U87_Human0.83573411
142GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.83360381
143SOX2_21211035_ChIP-Seq_LN229_Gbm0.83077920

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000537_abnormal_urethra_morphology3.84003877
2MP0000778_abnormal_nervous_system3.66737536
3MP0010030_abnormal_orbit_morphology2.84650039
4MP0003122_maternal_imprinting2.77890867
5MP0000569_abnormal_digit_pigmentation2.73399736
6MP0002653_abnormal_ependyma_morphology2.71296723
7MP0002822_catalepsy2.52133805
8MP0006276_abnormal_autonomic_nervous2.43120804
9MP0003121_genomic_imprinting2.30750213
10MP0005423_abnormal_somatic_nervous2.25656173
11MP0003385_abnormal_body_wall2.21678401
12MP0004859_abnormal_synaptic_plasticity2.19478927
13MP0009053_abnormal_anal_canal2.17161746
14MP0008789_abnormal_olfactory_epithelium2.16313383
15MP0000566_synostosis2.13439957
16MP0003890_abnormal_embryonic-extraembry2.13166680
17MP0001529_abnormal_vocalization2.09578142
18MP0005187_abnormal_penis_morphology2.05628273
19MP0003119_abnormal_digestive_system2.05036707
20MP0003861_abnormal_nervous_system2.03208568
21MP0003315_abnormal_perineum_morphology1.96680221
22MP0003880_abnormal_central_pattern1.93114114
23MP0002184_abnormal_innervation1.92580415
24MP0000049_abnormal_middle_ear1.91183883
25MP0001188_hyperpigmentation1.90721211
26MP0005499_abnormal_olfactory_system1.82717251
27MP0005394_taste/olfaction_phenotype1.82717251
28MP0006292_abnormal_olfactory_placode1.81027380
29MP0004142_abnormal_muscle_tone1.80548899
30MP0002282_abnormal_trachea_morphology1.78529001
31MP0003942_abnormal_urinary_system1.77354802
32MP0009745_abnormal_behavioral_response1.73556205
33MP0002249_abnormal_larynx_morphology1.73042237
34MP0004270_analgesia1.72975846
35MP0002735_abnormal_chemical_nociception1.70066679
36MP0002272_abnormal_nervous_system1.67157457
37MP0000631_abnormal_neuroendocrine_gland1.65557428
38MP0000955_abnormal_spinal_cord1.64967229
39MP0003787_abnormal_imprinting1.64423916
40MP0002938_white_spotting1.62673864
41MP0004858_abnormal_nervous_system1.62598290
42MP0005076_abnormal_cell_differentiation1.61995548
43MP0003136_yellow_coat_color1.56428914
44MP0004885_abnormal_endolymph1.54873605
45MP0000534_abnormal_ureter_morphology1.53927901
46MP0002751_abnormal_autonomic_nervous1.52446403
47MP0003938_abnormal_ear_development1.50244648
48MP0001970_abnormal_pain_threshold1.50092860
49MP0004133_heterotaxia1.48915911
50MP0002116_abnormal_craniofacial_bone1.48401130
51MP0002234_abnormal_pharynx_morphology1.48086004
52MP0004811_abnormal_neuron_physiology1.47897027
53MP0002152_abnormal_brain_morphology1.47480920
54MP0001440_abnormal_grooming_behavior1.46983120
55MP0001849_ear_inflammation1.46748247
56MP0002932_abnormal_joint_morphology1.45169537
57MP0003937_abnormal_limbs/digits/tail_de1.44675873
58MP0002064_seizures1.43571574
59MP0009046_muscle_twitch1.42759066
60MP0002067_abnormal_sensory_capabilities1.42401978
61MP0005377_hearing/vestibular/ear_phenot1.40860574
62MP0003878_abnormal_ear_physiology1.40860574
63MP0002102_abnormal_ear_morphology1.40702551
64MP0005248_abnormal_Harderian_gland1.38823850
65MP0002063_abnormal_learning/memory/cond1.37745913
66MP0003755_abnormal_palate_morphology1.35499183
67MP0003115_abnormal_respiratory_system1.35443649
68MP0001485_abnormal_pinna_reflex1.35178025
69MP0002081_perinatal_lethality1.33219292
70MP0001968_abnormal_touch/_nociception1.32232024
71MP0003935_abnormal_craniofacial_develop1.31390168
72MP0002233_abnormal_nose_morphology1.28089389
73MP0002882_abnormal_neuron_morphology1.26633775
74MP0002557_abnormal_social/conspecific_i1.26145506
75MP0001905_abnormal_dopamine_level1.26079000
76MP0009379_abnormal_foot_pigmentation1.23778870
77MP0003635_abnormal_synaptic_transmissio1.19873660
78MP0005551_abnormal_eye_electrophysiolog1.19631370
79MP0008877_abnormal_DNA_methylation1.19589826
80MP0000428_abnormal_craniofacial_morphol1.19225816
81MP0002084_abnormal_developmental_patter1.18349385
82MP0003123_paternal_imprinting1.18216720
83MP0009250_abnormal_appendicular_skeleto1.17451829
84MP0002085_abnormal_embryonic_tissue1.15535874
85MP0002697_abnormal_eye_size1.13105747
86MP0001984_abnormal_olfaction1.12228098
87MP0001293_anophthalmia1.10878554
88MP0002092_abnormal_eye_morphology1.09515957
89MP0008961_abnormal_basal_metabolism1.08915426
90MP0004924_abnormal_behavior1.08465508
91MP0005386_behavior/neurological_phenoty1.08465508
92MP0004197_abnormal_fetal_growth/weight/1.08153277
93MP0003283_abnormal_digestive_organ1.06373230
94MP0003567_abnormal_fetal_cardiomyocyte1.05261686
95MP0001286_abnormal_eye_development1.04708081
96MP0002909_abnormal_adrenal_gland1.04393544
97MP0002736_abnormal_nociception_after1.01927255
98MP0005195_abnormal_posterior_eye1.01397555
99MP0003011_delayed_dark_adaptation0.98630755
100MP0000733_abnormal_muscle_development0.98262269
101MP0001299_abnormal_eye_distance/0.97408119
102MP0005253_abnormal_eye_physiology0.96560918
103MP0001963_abnormal_hearing_physiology0.95227398
104MP0002114_abnormal_axial_skeleton0.95225317
105MP0002752_abnormal_somatic_nervous0.95113591
106MP0002066_abnormal_motor_capabilities/c0.95100839
107MP0003137_abnormal_impulse_conducting0.93323588
108MP0003698_abnormal_male_reproductive0.92019191
109MP0002177_abnormal_outer_ear0.91834674
110MP0002733_abnormal_thermal_nociception0.91043704
111MP0002734_abnormal_mechanical_nocicepti0.89521304
112MP0005645_abnormal_hypothalamus_physiol0.88920169
113MP0000432_abnormal_head_morphology0.87445633
114MP0006072_abnormal_retinal_apoptosis0.87322137
115MP0002089_abnormal_postnatal_growth/wei0.86718663
116MP0005410_abnormal_fertilization0.85567824
117MP0004742_abnormal_vestibular_system0.85165621
118MP0000462_abnormal_digestive_system0.84547616
119MP0002069_abnormal_eating/drinking_beha0.83750146
120MP0000516_abnormal_urinary_system0.82183903
121MP0005367_renal/urinary_system_phenotyp0.82183903
122MP0004145_abnormal_muscle_electrophysio0.81451686
123MP0008995_early_reproductive_senescence0.81189381
124MP0001486_abnormal_startle_reflex0.81109929
125MP0000026_abnormal_inner_ear0.80218398
126MP0002163_abnormal_gland_morphology0.79746680
127MP0005623_abnormal_meninges_morphology0.77572320
128MP0001340_abnormal_eyelid_morphology0.77521929
129MP0009672_abnormal_birth_weight0.77268436
130MP0005391_vision/eye_phenotype0.77145999
131MP0001502_abnormal_circadian_rhythm0.75748781
132MP0005670_abnormal_white_adipose0.75699489
133MP0008569_lethality_at_weaning0.75630030
134MP0002638_abnormal_pupillary_reflex0.74872956
135MP0009703_decreased_birth_body0.74697805
136MP0002111_abnormal_tail_morphology0.74032095
137MP0002572_abnormal_emotion/affect_behav0.71242269
138MP0010770_preweaning_lethality0.70318296

Predicted human phenotypes

RankGene SetZ-score
1Hyperacusis (HP:0010780)5.12616426
2Short 4th metacarpal (HP:0010044)4.69443614
3Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)4.69443614
4Cortical dysplasia (HP:0002539)4.09124690
5Myokymia (HP:0002411)3.79556283
6Abnormality of the 4th metacarpal (HP:0010012)3.73349553
7Renal duplication (HP:0000075)3.67338921
8Morphological abnormality of the middle ear (HP:0008609)3.55471450
9Elfin facies (HP:0004428)3.42479892
10Insomnia (HP:0100785)3.36709988
11Overriding aorta (HP:0002623)3.28826891
12Renovascular hypertension (HP:0100817)3.25202637
13Hepatoblastoma (HP:0002884)2.98397082
14Progressive cerebellar ataxia (HP:0002073)2.89744662
15Agitation (HP:0000713)2.88728444
16Nephronophthisis (HP:0000090)2.76037891
17Pachygyria (HP:0001302)2.75009353
18Tented upper lip vermilion (HP:0010804)2.70228837
19Molar tooth sign on MRI (HP:0002419)2.67743381
20Abnormality of midbrain morphology (HP:0002418)2.67743381
21Type II lissencephaly (HP:0007260)2.67326945
22Retinal dysplasia (HP:0007973)2.66020627
23Gait imbalance (HP:0002141)2.63000504
24Abnormality of the intervertebral disk (HP:0005108)2.60959286
25Genetic anticipation (HP:0003743)2.57883217
26Lissencephaly (HP:0001339)2.56326474
27Flat cornea (HP:0007720)2.56160559
28Increased nuchal translucency (HP:0010880)2.51824300
29Abnormality of the diencephalon (HP:0010662)2.50923914
30Amblyopia (HP:0000646)2.50912629
31Abnormal hair whorl (HP:0010721)2.49037107
32Abnormality of the lower motor neuron (HP:0002366)2.48021104
33Septo-optic dysplasia (HP:0100842)2.47996804
34Amyotrophic lateral sclerosis (HP:0007354)2.47489824
35Supranuclear gaze palsy (HP:0000605)2.44068704
36Sacral dimple (HP:0000960)2.43666283
37Focal seizures (HP:0007359)2.43507560
38Pancreatic fibrosis (HP:0100732)2.43258274
39Abnormality of the labia minora (HP:0012880)2.40061729
40Shallow orbits (HP:0000586)2.39460859
41Rib fusion (HP:0000902)2.39195619
42Medial flaring of the eyebrow (HP:0010747)2.38374249
43Limb dystonia (HP:0002451)2.38018956
44Pancreatic cysts (HP:0001737)2.37055736
45Apathy (HP:0000741)2.36765161
46High anterior hairline (HP:0009890)2.32324220
47Broad-based gait (HP:0002136)2.31214141
48Oligodactyly (hands) (HP:0001180)2.30926462
49Pointed chin (HP:0000307)2.30730673
50Chronic hepatic failure (HP:0100626)2.28519871
51Wrist flexion contracture (HP:0001239)2.28225100
52Shawl scrotum (HP:0000049)2.27216854
53True hermaphroditism (HP:0010459)2.26720480
54Shoulder girdle muscle weakness (HP:0003547)2.26513992
55Abnormality of the renal medulla (HP:0100957)2.25858233
56Megalocornea (HP:0000485)2.25766663
57Anophthalmia (HP:0000528)2.24030757
58Spina bifida occulta (HP:0003298)2.23814674
59Epileptic encephalopathy (HP:0200134)2.22407700
60Failure to thrive in infancy (HP:0001531)2.22359710
61Hypoplasia of the brainstem (HP:0002365)2.22277202
62Aplasia/Hypoplasia of the brainstem (HP:0007362)2.22277202
63Bony spicule pigmentary retinopathy (HP:0007737)2.21444333
64Anterior segment dysgenesis (HP:0007700)2.20867008
65Cerebellar dysplasia (HP:0007033)2.20206284
66Inappropriate behavior (HP:0000719)2.18790971
67Obsessive-compulsive behavior (HP:0000722)2.18649028
68Heterotopia (HP:0002282)2.17905937
69Diminished motivation (HP:0000745)2.17162211
70Anencephaly (HP:0002323)2.16601876
71Patellar dislocation (HP:0002999)2.16596920
72Short philtrum (HP:0000322)2.16565028
73Optic nerve hypoplasia (HP:0000609)2.16281829
74Vaginal atresia (HP:0000148)2.14401312
75Trigonocephaly (HP:0000243)2.13483991
76Drooling (HP:0002307)2.13369691
77Excessive salivation (HP:0003781)2.13369691
78Cutaneous finger syndactyly (HP:0010554)2.12452940
79Focal motor seizures (HP:0011153)2.12073971
80Broad alveolar ridges (HP:0000187)2.11217588
81Genital tract atresia (HP:0001827)2.10413871
82Exotropia (HP:0000577)2.09427325
83Growth hormone deficiency (HP:0000824)2.05740614
84Germ cell neoplasia (HP:0100728)2.05497586
85Congenital primary aphakia (HP:0007707)2.03508823
86Sclerocornea (HP:0000647)2.01807909
87Protruding tongue (HP:0010808)2.00026034
88Midline defect of the nose (HP:0004122)1.99463490
89Abnormality of the astrocytes (HP:0100707)1.98417123
90Astrocytoma (HP:0009592)1.98417123
91Neoplasm of the heart (HP:0100544)1.98349239
92Nephrogenic diabetes insipidus (HP:0009806)1.97824515
93Absent septum pellucidum (HP:0001331)1.97283227
94Pendular nystagmus (HP:0012043)1.97073799
95Febrile seizures (HP:0002373)1.95250975
96Lymphangioma (HP:0100764)1.94747053
97Cutaneous syndactyly (HP:0012725)1.94098836
98Specific learning disability (HP:0001328)1.94078845
99Abnormal pancreas size (HP:0012094)1.93637069
100Deviation of the hallux (HP:0010051)1.92556052
101Precocious puberty (HP:0000826)1.91930199
102Oligodactyly (HP:0012165)1.91921090
103Generalized hypotonia (HP:0001290)1.90967502
104Hyperventilation (HP:0002883)1.90569354
105Optic nerve coloboma (HP:0000588)1.90436816
106Intestinal atresia (HP:0011100)1.89703559
107Sleep apnea (HP:0010535)1.89539245
108Hallux valgus (HP:0001822)1.89227775
109Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.89009792
110Bowel diverticulosis (HP:0005222)1.88303738
111Abnormality of chromosome segregation (HP:0002916)1.87466503
112Meningocele (HP:0002435)1.85286025
113Colon cancer (HP:0003003)1.84993509
114Bladder diverticulum (HP:0000015)1.84516168
115Aplasia/Hypoplasia of the sternum (HP:0006714)1.83084964
116Narrow forehead (HP:0000341)1.82669823
117Urinary bladder sphincter dysfunction (HP:0002839)1.82623415
118Large eyes (HP:0001090)1.82436831
119Leiomyosarcoma (HP:0100243)1.82273315
120Uterine leiomyosarcoma (HP:0002891)1.82273315
121Cystic liver disease (HP:0006706)1.82067124
122Congenital stationary night blindness (HP:0007642)1.80564847
123Spastic tetraplegia (HP:0002510)1.80525494
124Fetal akinesia sequence (HP:0001989)1.80165131
125Atrophy/Degeneration involving motor neurons (HP:0007373)1.79903720
126Poor coordination (HP:0002370)1.79737194
127Vesicoureteral reflux (HP:0000076)1.78720366
128Polymicrogyria (HP:0002126)1.78249639
129Ependymoma (HP:0002888)1.78164563
130Anteriorly placed anus (HP:0001545)1.77797479
131Pelvic girdle muscle weakness (HP:0003749)1.77725796
132Patellar aplasia (HP:0006443)1.75942732
133Esotropia (HP:0000565)1.75807484
134Aqueductal stenosis (HP:0002410)1.75042579
135Disinhibition (HP:0000734)1.74342669
136Autism (HP:0000717)1.74073221
137Cutis marmorata (HP:0000965)1.73673282
138Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.73309624
139Micropenis (HP:0000054)1.72930738
140Hemiparesis (HP:0001269)1.72230886
141Impulsivity (HP:0100710)1.71891906
142Medulloblastoma (HP:0002885)1.71379952
143Aplasia/Hypoplasia of the patella (HP:0006498)1.71360876
144Poor suck (HP:0002033)1.70257230
145Abnormal eating behavior (HP:0100738)1.69516420
146Polyphagia (HP:0002591)1.69136206
147Macroorchidism (HP:0000053)1.68655642
148Labial hypoplasia (HP:0000066)1.67769867
149Wide cranial sutures (HP:0010537)1.67512578
150Megalencephaly (HP:0001355)1.67299502
151Anomalous pulmonary venous return (HP:0010772)1.66746229
152Abnormality of the aortic arch (HP:0012303)1.66525872
153Abnormality of the metopic suture (HP:0005556)1.66369589
154Renal dysplasia (HP:0000110)1.65808318
155Congenital diaphragmatic hernia (HP:0000776)1.65745651
156Abnormal rod and cone electroretinograms (HP:0008323)1.65289479
157Adducted thumb (HP:0001181)1.65019864
158Attention deficit hyperactivity disorder (HP:0007018)1.64643084
159Facial hemangioma (HP:0000329)1.64513176
160Dandy-Walker malformation (HP:0001305)1.64178368
161Proximal placement of thumb (HP:0009623)1.63938326
162Hypogonadotrophic hypogonadism (HP:0000044)1.63485127
163Renal hypoplasia (HP:0000089)1.63249663
164Arnold-Chiari malformation (HP:0002308)1.62057971
165Abnormality of the corticospinal tract (HP:0002492)1.61919053
166Hypoplasia of the corpus callosum (HP:0002079)1.59997725
167Sporadic (HP:0003745)1.59095564
168Volvulus (HP:0002580)1.57957712
169Transitional cell carcinoma of the bladder (HP:0006740)1.57733663
170Ankle clonus (HP:0011448)1.57058740

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK16.67277133
2CASK4.13433866
3EPHB23.72059809
4DYRK23.10238739
5SIK22.90071275
6KSR12.80764922
7ERBB32.75909766
8ICK2.24737819
9MAP3K102.24270263
10NTRK22.05177756
11CAMK1D2.03230250
12MAPK131.97601929
13TYRO31.93497043
14FGFR21.86782828
15NTRK31.78956255
16LIMK11.65765849
17SIK31.64386019
18WNK31.63115639
19UHMK11.60168220
20TRIB31.58671346
21ERBB21.56978911
22MAP3K41.56430236
23BCR1.53494819
24MAP3K91.51575733
25MKNK11.47997299
26WNK41.41617143
27PRKCG1.41138567
28BRD41.39498833
29EEF2K1.38719315
30DYRK31.35089141
31MINK11.33413743
32PINK11.32478123
33CSNK1A1L1.32469306
34PDGFRA1.31671447
35CDK191.31539520
36CSNK1G31.30153204
37CAMKK11.23410741
38SRPK11.22299803
39PAK61.21376883
40CSNK1G21.17816988
41MAP2K71.12969466
42LATS21.12592296
43PKN21.09182714
44EPHA31.09044856
45INSRR1.05702764
46DYRK1B1.05633889
47ADRBK21.02961004
48PHKG21.00947029
49PHKG11.00947029
50MAPK150.98520501
51NTRK10.97447694
52MKNK20.97417886
53CDC70.94465237
54FGFR10.93579361
55CSNK1G10.93401962
56DDR20.92559986
57SGK20.88275099
58CAMK1G0.87932374
59DYRK1A0.87541820
60CAMKK20.86812187
61PTK60.86643207
62MAP4K20.84700270
63TGFBR10.84253143
64CDK120.84087286
65CAMK10.83870535
66EPHA40.82613488
67MUSK0.81774427
68CDK180.80466389
69MARK20.79232749
70PNCK0.79109647
71CAMK40.77960751
72MTOR0.76639199
73FRK0.75940813
74CDK50.75784200
75PRKCZ0.74701344
76PRKCH0.74694303
77TESK10.71727392
78CDK150.71370643
79TNIK0.68766241
80TESK20.68506708
81CDK140.65653068
82ILK0.65155058
83PLK40.64663737
84MAPK90.64630191
85CDK11A0.64115610
86PRKD30.64105909
87DAPK20.60884708
88RPS6KA20.59998309
89CHEK20.57990693
90PAK30.57954501
91ATR0.56499062
92PAK20.54749220
93PAK40.53609404
94GRK10.53568105
95LATS10.53173032
96MAP3K60.52782603
97RET0.52225775
98PLK20.52045725
99RIPK10.51287038
100CDK10.50129846
101RPS6KA60.50060149
102WNK10.49789182
103NEK20.49444978
104PASK0.49437089
105PRKCE0.49074277
106PKN10.48544648
107CSNK1E0.48543654
108IRAK20.48511574
109SGK4940.48403492
110SGK2230.48403492
111STK160.47035264
112MAP2K40.46491733
113TRIM280.46414833
114ROCK10.46365872
115TAOK10.46313181
116CAMK2A0.44625217
117RPS6KA10.43867420
118CDC42BPA0.43091773
119CDK30.43038746
120PRKACA0.42952745
121SGK30.41616589
122MAPK80.40990745
123STK38L0.40931220
124CDK20.40509980
125AURKA0.40457815
126OXSR10.40400887
127SGK10.40353441
128BMPR1B0.39400205
129PRKG10.39377257
130CSNK1A10.38422234
131CLK10.38141071
132ADRBK10.38140900
133TAF10.37945660
134GSK3B0.37879744
135PLK30.37788316
136PRKAA10.37414128
137CSNK1D0.37297277
138FYN0.36304883
139PRKDC0.36244201
140ALK0.35932859
141RPS6KB20.35737944
142STK110.35486267

Predicted pathways (KEGG)

RankGene SetZ-score
1Axon guidance_Homo sapiens_hsa043603.42305903
2Basal cell carcinoma_Homo sapiens_hsa052173.19462215
3Colorectal cancer_Homo sapiens_hsa052102.63431615
4Notch signaling pathway_Homo sapiens_hsa043302.42214727
5Cardiac muscle contraction_Homo sapiens_hsa042602.38061851
6Hedgehog signaling pathway_Homo sapiens_hsa043402.36973771
7Hippo signaling pathway_Homo sapiens_hsa043902.31032366
8Endometrial cancer_Homo sapiens_hsa052132.25557360
9Phototransduction_Homo sapiens_hsa047442.20600648
10Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.18868143
11Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045502.16595256
12Spliceosome_Homo sapiens_hsa030402.13561333
13mRNA surveillance pathway_Homo sapiens_hsa030152.11931072
14Pathogenic Escherichia coli infection_Homo sapiens_hsa051302.04524909
15Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.95905420
16Wnt signaling pathway_Homo sapiens_hsa043101.88775651
17Oxidative phosphorylation_Homo sapiens_hsa001901.76509578
18Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.71649495
19Parkinsons disease_Homo sapiens_hsa050121.70849185
20Viral myocarditis_Homo sapiens_hsa054161.70421068
21Taste transduction_Homo sapiens_hsa047421.66490950
22Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.64822874
23Chronic myeloid leukemia_Homo sapiens_hsa052201.62585213
24MicroRNAs in cancer_Homo sapiens_hsa052061.58054409
25Gap junction_Homo sapiens_hsa045401.52449761
26Neurotrophin signaling pathway_Homo sapiens_hsa047221.51751393
27Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.51290409
28Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.49480440
29Insulin secretion_Homo sapiens_hsa049111.49018123
30Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.45245856
31Renal cell carcinoma_Homo sapiens_hsa052111.44181629
32Serotonergic synapse_Homo sapiens_hsa047261.43742535
33Butanoate metabolism_Homo sapiens_hsa006501.42250026
34ErbB signaling pathway_Homo sapiens_hsa040121.41975809
35Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.36505663
36Olfactory transduction_Homo sapiens_hsa047401.35552908
37Huntingtons disease_Homo sapiens_hsa050161.34297191
38alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.26848733
39Dopaminergic synapse_Homo sapiens_hsa047281.26413227
40Melanogenesis_Homo sapiens_hsa049161.26146567
41Adherens junction_Homo sapiens_hsa045201.25500522
42Oocyte meiosis_Homo sapiens_hsa041141.24973819
43Steroid biosynthesis_Homo sapiens_hsa001001.23583803
44Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.23378616
45Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.22682129
46Alzheimers disease_Homo sapiens_hsa050101.22445528
47VEGF signaling pathway_Homo sapiens_hsa043701.21677370
48Ribosome_Homo sapiens_hsa030101.20928269
49Glioma_Homo sapiens_hsa052141.20715299
50mTOR signaling pathway_Homo sapiens_hsa041501.19344619
51Lysine degradation_Homo sapiens_hsa003101.17976737
52Cell cycle_Homo sapiens_hsa041101.16673944
53Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.15546772
54Non-small cell lung cancer_Homo sapiens_hsa052231.14565729
55Linoleic acid metabolism_Homo sapiens_hsa005911.14157639
56Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.13624311
57Proteoglycans in cancer_Homo sapiens_hsa052051.12179892
58Pancreatic cancer_Homo sapiens_hsa052121.09356833
59Pathways in cancer_Homo sapiens_hsa052001.09099176
60Amphetamine addiction_Homo sapiens_hsa050311.08668752
61Cocaine addiction_Homo sapiens_hsa050301.08656524
62Thyroid hormone signaling pathway_Homo sapiens_hsa049191.07834318
63Nicotine addiction_Homo sapiens_hsa050331.07659322
64Alcoholism_Homo sapiens_hsa050341.07108894
65TGF-beta signaling pathway_Homo sapiens_hsa043501.05126287
66Cholinergic synapse_Homo sapiens_hsa047251.03005864
67Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.99916713
68Tight junction_Homo sapiens_hsa045300.98426335
69Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.97779848
70Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.95008821
71Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.92427593
72cAMP signaling pathway_Homo sapiens_hsa040240.92375399
73Type II diabetes mellitus_Homo sapiens_hsa049300.91706908
74RNA transport_Homo sapiens_hsa030130.89746911
75Ether lipid metabolism_Homo sapiens_hsa005650.88979275
76Estrogen signaling pathway_Homo sapiens_hsa049150.88010187
77Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.87696996
78Glutamatergic synapse_Homo sapiens_hsa047240.87662537
79Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.87083849
80HTLV-I infection_Homo sapiens_hsa051660.85828879
81Basal transcription factors_Homo sapiens_hsa030220.81509434
82Rap1 signaling pathway_Homo sapiens_hsa040150.80140717
83Transcriptional misregulation in cancer_Homo sapiens_hsa052020.78550751
84AMPK signaling pathway_Homo sapiens_hsa041520.77130789
85Small cell lung cancer_Homo sapiens_hsa052220.77068260
86Gastric acid secretion_Homo sapiens_hsa049710.75834710
87Insulin signaling pathway_Homo sapiens_hsa049100.75554803
88Circadian entrainment_Homo sapiens_hsa047130.75359468
89Choline metabolism in cancer_Homo sapiens_hsa052310.75337717
90MAPK signaling pathway_Homo sapiens_hsa040100.73961828
91Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.73603666
92Calcium signaling pathway_Homo sapiens_hsa040200.73428134
93Aldosterone synthesis and secretion_Homo sapiens_hsa049250.72332682
94AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.71939600
95GABAergic synapse_Homo sapiens_hsa047270.71627861
96Central carbon metabolism in cancer_Homo sapiens_hsa052300.71505614
97Focal adhesion_Homo sapiens_hsa045100.70696949
98Bladder cancer_Homo sapiens_hsa052190.70158118
99Longevity regulating pathway - mammal_Homo sapiens_hsa042110.68510236
100Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.68049982
101Selenocompound metabolism_Homo sapiens_hsa004500.68029612
102Oxytocin signaling pathway_Homo sapiens_hsa049210.65783666
103Carbohydrate digestion and absorption_Homo sapiens_hsa049730.64398618
104Salivary secretion_Homo sapiens_hsa049700.64338494
105GnRH signaling pathway_Homo sapiens_hsa049120.64272071
106FoxO signaling pathway_Homo sapiens_hsa040680.63577346
107Prolactin signaling pathway_Homo sapiens_hsa049170.61974928
108Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.61778070
109N-Glycan biosynthesis_Homo sapiens_hsa005100.61689337
110Ovarian steroidogenesis_Homo sapiens_hsa049130.60819312
111Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.60650581
112Maturity onset diabetes of the young_Homo sapiens_hsa049500.59955831
113Regulation of actin cytoskeleton_Homo sapiens_hsa048100.59836118
114Melanoma_Homo sapiens_hsa052180.59273442
115Prostate cancer_Homo sapiens_hsa052150.58756879
116T cell receptor signaling pathway_Homo sapiens_hsa046600.57948178
117Ras signaling pathway_Homo sapiens_hsa040140.56877470
118Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.56719598
119Endocytosis_Homo sapiens_hsa041440.56493376
120Phospholipase D signaling pathway_Homo sapiens_hsa040720.56417652
121Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.55829403
122RNA polymerase_Homo sapiens_hsa030200.55688146
123Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.54755135
124Shigellosis_Homo sapiens_hsa051310.51677733
125Synaptic vesicle cycle_Homo sapiens_hsa047210.51215992
126Protein export_Homo sapiens_hsa030600.50669127
127Fatty acid biosynthesis_Homo sapiens_hsa000610.49223144
128Epstein-Barr virus infection_Homo sapiens_hsa051690.48436328
129Morphine addiction_Homo sapiens_hsa050320.48398701
130PI3K-Akt signaling pathway_Homo sapiens_hsa041510.47823542
131Sphingolipid signaling pathway_Homo sapiens_hsa040710.47267796
132Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.47111704
133Salmonella infection_Homo sapiens_hsa051320.46929407
134Dorso-ventral axis formation_Homo sapiens_hsa043200.46727677
135Viral carcinogenesis_Homo sapiens_hsa052030.46532722
136Tryptophan metabolism_Homo sapiens_hsa003800.46205097
137Long-term depression_Homo sapiens_hsa047300.45294808
138Long-term potentiation_Homo sapiens_hsa047200.44974667
139Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.44585359
140Dilated cardiomyopathy_Homo sapiens_hsa054140.43520923
141Vascular smooth muscle contraction_Homo sapiens_hsa042700.42862321
142Renin secretion_Homo sapiens_hsa049240.38809484
143Fanconi anemia pathway_Homo sapiens_hsa034600.38648753
144Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.38339384
145Collecting duct acid secretion_Homo sapiens_hsa049660.37032049
146Bile secretion_Homo sapiens_hsa049760.34633939
147Sulfur relay system_Homo sapiens_hsa041220.34527171
148Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.31783338
149Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.30749560
150Glycerophospholipid metabolism_Homo sapiens_hsa005640.28961660

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