GPR107

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1COPI coating of Golgi vesicle (GO:0048205)4.77212603
2Golgi transport vesicle coating (GO:0048200)4.77212603
3maintenance of protein localization in endoplasmic reticulum (GO:0035437)4.00828559
4skin morphogenesis (GO:0043589)3.96630062
5protein retention in ER lumen (GO:0006621)3.85409037
6regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.68681388
7cell-substrate adherens junction assembly (GO:0007045)3.48744912
8focal adhesion assembly (GO:0048041)3.48744912
9dichotomous subdivision of an epithelial terminal unit (GO:0060600)3.45082070
10retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.35062755
11cellular response to vitamin D (GO:0071305)3.29982573
12adhesion of symbiont to host cell (GO:0044650)3.29275297
13virion attachment to host cell (GO:0019062)3.29275297
14barbed-end actin filament capping (GO:0051016)3.22687839
15regulation of early endosome to late endosome transport (GO:2000641)3.21327355
16modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.19531331
17modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.19531331
18positive regulation by organism of defense response of other organism involved in symbiotic interact3.19531331
19modulation by symbiont of host immune response (GO:0052553)3.19531331
20positive regulation by symbiont of host defense response (GO:0052509)3.19531331
21modulation by symbiont of host defense response (GO:0052031)3.19531331
22cellular response to vitamin (GO:0071295)3.15957007
23auditory behavior (GO:0031223)3.09758775
24wound healing, spreading of epidermal cells (GO:0035313)3.09339374
25cytoskeletal anchoring at plasma membrane (GO:0007016)3.00191070
26axon extension involved in axon guidance (GO:0048846)2.98625881
27neuron projection extension involved in neuron projection guidance (GO:1902284)2.98625881
28glomerular visceral epithelial cell development (GO:0072015)2.97536033
29innervation (GO:0060384)2.94492629
30hemidesmosome assembly (GO:0031581)2.92463916
31paraxial mesoderm development (GO:0048339)2.89212264
32regulation of glucose import in response to insulin stimulus (GO:2001273)2.86670188
33stress fiber assembly (GO:0043149)2.85255347
34Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.84644695
35vesicle coating (GO:0006901)2.82953987
36surfactant homeostasis (GO:0043129)2.81031077
37cell adhesion mediated by integrin (GO:0033627)2.80595893
38negative regulation of fatty acid transport (GO:2000192)2.77756744
39glomerular epithelial cell development (GO:0072310)2.76743280
40ruffle organization (GO:0031529)2.73467437
41vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.72606544
42I-kappaB phosphorylation (GO:0007252)2.71940960
43hypotonic response (GO:0006971)2.71347848
44regulation of establishment of planar polarity (GO:0090175)2.70952140
45mating behavior (GO:0007617)2.70578036
46glomerular basement membrane development (GO:0032836)2.68417701
47adhesion of symbiont to host (GO:0044406)2.66971640
48membrane protein ectodomain proteolysis (GO:0006509)2.66758212
49lung-associated mesenchyme development (GO:0060484)2.65791224
50histone H3-K36 demethylation (GO:0070544)2.65549411
51regulation of cardioblast differentiation (GO:0051890)2.65272991
52regulation of NFAT protein import into nucleus (GO:0051532)2.61392854
53activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.61132793
54camera-type eye morphogenesis (GO:0048593)2.59947511
55semaphorin-plexin signaling pathway (GO:0071526)2.58316004
56mesenchymal-epithelial cell signaling (GO:0060638)2.57857077
57ectoderm development (GO:0007398)2.56470285
58peptidyl-proline hydroxylation (GO:0019511)2.56270730
59positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.55994080
60branching involved in mammary gland duct morphogenesis (GO:0060444)2.54945153
61positive regulation of blood vessel endothelial cell migration (GO:0043536)2.52190716
62activation of Rac GTPase activity (GO:0032863)2.50387829
63protein hydroxylation (GO:0018126)2.50359578
64G-protein coupled receptor internalization (GO:0002031)2.50035030
65glial cell proliferation (GO:0014009)2.48028781
66plasma membrane repair (GO:0001778)2.47515463
67response to auditory stimulus (GO:0010996)2.47017463
68maternal placenta development (GO:0001893)2.46594929
69positive regulation of nuclease activity (GO:0032075)2.46039860
70response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.45317033
71response to host immune response (GO:0052572)2.45317033
72endothelial cell morphogenesis (GO:0001886)2.44176522
73establishment of apical/basal cell polarity (GO:0035089)2.43932250
74eye morphogenesis (GO:0048592)2.43558105
75response to laminar fluid shear stress (GO:0034616)2.43267098
76cellular copper ion homeostasis (GO:0006878)2.42790456
77cortical actin cytoskeleton organization (GO:0030866)2.42305932
78regulation of nucleobase-containing compound transport (GO:0032239)2.40187212
79positive regulation of receptor recycling (GO:0001921)2.38363301
80regulation of p38MAPK cascade (GO:1900744)2.38235817
81cell-cell junction maintenance (GO:0045217)2.37800119
82branching involved in salivary gland morphogenesis (GO:0060445)2.37173307
83cellular response to prostaglandin stimulus (GO:0071379)2.36966934
84endoplasmic reticulum unfolded protein response (GO:0030968)2.36890492
85chondrocyte development (GO:0002063)2.36413969
86positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.35690497
87substrate-dependent cell migration (GO:0006929)2.35654695
88endodermal cell differentiation (GO:0035987)2.35555742
89protein heterotrimerization (GO:0070208)2.34537690
90embryo implantation (GO:0007566)2.34535638
91collagen metabolic process (GO:0032963)2.34428432
92COPII vesicle coating (GO:0048208)2.34161682
93ER-nucleus signaling pathway (GO:0006984)2.34044119
94response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.33949907
95response to host (GO:0075136)2.33949907
96response to host defenses (GO:0052200)2.33949907
97endothelial cell chemotaxis (GO:0035767)2.33522377
98startle response (GO:0001964)2.31646858
99gland morphogenesis (GO:0022612)2.31472351
100extracellular matrix disassembly (GO:0022617)2.31285968
101positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.30734112
102apical protein localization (GO:0045176)2.30574466
103cell morphogenesis involved in neuron differentiation (GO:0048667)2.29721093
104macrophage activation involved in immune response (GO:0002281)2.29195465
105adherens junction organization (GO:0034332)2.28767410
106convergent extension (GO:0060026)2.28160478
107regulation of water loss via skin (GO:0033561)2.27405484
108regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:00432.26611960
109regulation of protein polyubiquitination (GO:1902914)2.25508326
110atrioventricular valve morphogenesis (GO:0003181)2.24785951
111embryonic process involved in female pregnancy (GO:0060136)2.24502733
112retina vasculature morphogenesis in camera-type eye (GO:0061299)2.24383234
113bundle of His cell to Purkinje myocyte communication (GO:0086069)2.23619941
114ganglion development (GO:0061548)2.23343761
115chondrocyte proliferation (GO:0035988)2.22719885
116actin filament bundle assembly (GO:0051017)2.22495906
117actin filament bundle organization (GO:0061572)2.22495906
118regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.22191674
119cortical cytoskeleton organization (GO:0030865)2.20706924
120regulation of phospholipid biosynthetic process (GO:0071071)2.20669050
121cellular response to unfolded protein (GO:0034620)2.20266236
122iron ion import (GO:0097286)2.20182164
123non-canonical Wnt signaling pathway (GO:0035567)2.19530197
124desmosome organization (GO:0002934)2.19039743
125regulation of epidermal growth factor-activated receptor activity (GO:0007176)2.18965423
126regulation of mammary gland epithelial cell proliferation (GO:0033599)2.18764279
127regulation of extracellular matrix disassembly (GO:0010715)2.18544570
128wound healing, spreading of cells (GO:0044319)2.17541846
129cell-substrate junction assembly (GO:0007044)2.17537959
130regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.16827953
131vascular endothelial growth factor signaling pathway (GO:0038084)2.14035028
132macroautophagy (GO:0016236)2.13907695
133regulation of cell fate specification (GO:0042659)2.13411248
134ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.12663275
135mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)2.11978090
136renal filtration (GO:0097205)2.11917288
137heparan sulfate proteoglycan biosynthetic process (GO:0015012)2.10295941
138dorsal/ventral axis specification (GO:0009950)2.09582333
139positive regulation of p38MAPK cascade (GO:1900745)2.09404315
140protein kinase C signaling (GO:0070528)2.08392567
141insulin-like growth factor receptor signaling pathway (GO:0048009)2.07666591
142apoptotic cell clearance (GO:0043277)2.06590392
143adherens junction assembly (GO:0034333)2.06550911
144epithelial cell differentiation involved in prostate gland development (GO:0060742)2.06363038
145mannose metabolic process (GO:0006013)2.06235477
146regulation of hippo signaling (GO:0035330)2.04823344
147collagen fibril organization (GO:0030199)2.03922247
148protein localization to endosome (GO:0036010)2.03616476
149basement membrane organization (GO:0071711)2.02113315
150regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.01868389
151planar cell polarity pathway involved in neural tube closure (GO:0090179)2.00841075
152negative regulation of cell fate specification (GO:0009996)2.00055871
153phosphatidylinositol 3-kinase signaling (GO:0014065)1.99346416
154negative regulation of Rho protein signal transduction (GO:0035024)1.99240470
155cellular response to interferon-alpha (GO:0035457)1.98663134
156hippo signaling (GO:0035329)1.97092004
157epithelial cell-cell adhesion (GO:0090136)1.95096421
158multicellular organismal catabolic process (GO:0044243)1.94793907
159embryonic camera-type eye development (GO:0031076)1.94662196
160mesenchymal cell differentiation (GO:0048762)1.94660083
161negative chemotaxis (GO:0050919)1.93139650
162bone trabecula formation (GO:0060346)1.92940044
163positive regulation of catenin import into nucleus (GO:0035413)1.92269119
164microglial cell activation (GO:0001774)1.91001101
165regulation of podosome assembly (GO:0071801)1.90922127
166collagen catabolic process (GO:0030574)1.90672360
167regulation of branching involved in salivary gland morphogenesis (GO:0060693)1.90230890
168multicellular organismal macromolecule metabolic process (GO:0044259)1.89329488
169fibroblast migration (GO:0010761)1.88902728
170negative regulation of chondrocyte differentiation (GO:0032331)1.88175868
171heart morphogenesis (GO:0003007)1.88152605

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human4.48121557
2TRIM28_21343339_ChIP-Seq_HEK293_Human2.93310197
3CLOCK_20551151_ChIP-Seq_293T_Human2.71054182
4STAT6_21828071_ChIP-Seq_BEAS2B_Human2.50447791
5VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.39083678
6ZNF263_19887448_ChIP-Seq_K562_Human2.37480872
7ELK3_25401928_ChIP-Seq_HUVEC_Human2.16953562
8CDX2_19796622_ChIP-Seq_MESCs_Mouse2.13605099
9THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.12945394
10RACK7_27058665_Chip-Seq_MCF-7_Human2.10697890
11EGR1_19374776_ChIP-ChIP_THP-1_Human2.08188613
12* SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.07630206
13KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human2.02292193
14LXR_22292898_ChIP-Seq_THP-1_Human1.96495829
15ZFP281_18757296_ChIP-ChIP_E14_Mouse1.93866955
16ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.90934473
17DROSHA_22980978_ChIP-Seq_HELA_Human1.89390275
18AHR_22903824_ChIP-Seq_MCF-7_Human1.83836202
19NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.80107973
20ZNF217_24962896_ChIP-Seq_MCF-7_Human1.76585743
21ESR1_20079471_ChIP-ChIP_T-47D_Human1.73038893
22KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.72336511
23KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.71468567
24TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.70160217
25SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.66569027
26ESR2_21235772_ChIP-Seq_MCF-7_Human1.64342689
27TCF7_22412390_ChIP-Seq_EML_Mouse1.62455904
28ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.60942884
29ERG_21242973_ChIP-ChIP_JURKAT_Human1.53790496
30EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.53613704
31KDM2B_26808549_Chip-Seq_DND41_Human1.53004165
32CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.51792466
33PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.51425141
34FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.46820323
35SOX9_24532713_ChIP-Seq_HFSC_Mouse1.46406484
36ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.45089805
37UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.45048854
38EP300_21415370_ChIP-Seq_HL-1_Mouse1.44224729
39ARNT_22903824_ChIP-Seq_MCF-7_Human1.44094524
40HIF1A_21447827_ChIP-Seq_MCF-7_Human1.42495672
41SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.41465188
42TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.40798540
43CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.38492370
44ESR1_21235772_ChIP-Seq_MCF-7_Human1.37340057
45GATA2_21666600_ChIP-Seq_HMVEC_Human1.35767028
46* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.35013639
47Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.34995224
48SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.34320393
49UBF1/2_26484160_Chip-Seq_HMECs_Human1.34219607
50PPAR_26484153_Chip-Seq_NCI-H1993_Human1.34059627
51EED_16625203_ChIP-ChIP_MESCs_Mouse1.32534985
52ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.31612899
53RUNX1_27514584_Chip-Seq_MCF-7_Human1.31238321
54MYC_22102868_ChIP-Seq_BL_Human1.30738274
55SMAD3_21741376_ChIP-Seq_HESCs_Human1.29579359
56RARG_19884340_ChIP-ChIP_MEFs_Mouse1.29259888
57RNF2_27304074_Chip-Seq_ESCs_Mouse1.29152098
58KDM2B_26808549_Chip-Seq_JURKAT_Human1.28979913
59ATF3_27146783_Chip-Seq_COLON_Human1.28818959
60SOX2_27498859_Chip-Seq_STOMACH_Mouse1.28082981
61SMAD_19615063_ChIP-ChIP_OVARY_Human1.27871031
62WT1_19549856_ChIP-ChIP_CCG9911_Human1.27007678
63WT1_25993318_ChIP-Seq_PODOCYTE_Human1.26781413
64TP53_22127205_ChIP-Seq_IMR90_Human1.24432610
65EZH2_18974828_ChIP-Seq_MESCs_Mouse1.23911939
66RNF2_18974828_ChIP-Seq_MESCs_Mouse1.23911939
67CJUN_26792858_Chip-Seq_BT549_Human1.23147599
68ISL1_27105846_Chip-Seq_CPCs_Mouse1.22382637
69WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.22225848
70VDR_21846776_ChIP-Seq_THP-1_Human1.21928075
71SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.21526287
72SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.21526287
73TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.21428624
74TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.21223619
75TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.21020738
76SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.21001458
77SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.20678298
78FOXO3_23340844_ChIP-Seq_DLD1_Human1.20550548
79SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.20441118
80NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.20042754
81EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.19878727
82PIAS1_25552417_ChIP-Seq_VCAP_Human1.18466912
83ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.17830200
84PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.17789118
85TP53_16413492_ChIP-PET_HCT116_Human1.17330547
86SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.15966775
87ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.15824859
88SALL1_21062744_ChIP-ChIP_HESCs_Human1.13262326
89KDM2B_26808549_Chip-Seq_K562_Human1.13035610
90MTF2_20144788_ChIP-Seq_MESCs_Mouse1.12679279
91NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.12436413
92NRF2_20460467_ChIP-Seq_MEFs_Mouse1.12436413
93TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.12322557
94ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.12136424
95CTNNB1_20460455_ChIP-Seq_HCT116_Human1.10982117
96CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.10606849
97SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.10477167
98GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.10152824
99VDR_24787735_ChIP-Seq_THP-1_Human1.09094833
100TCF4_18268006_ChIP-ChIP_LS174T_Human1.09077574
101* CREB1_26743006_Chip-Seq_LNCaP_Human1.08994406
102CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.08667799
103KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.08226042
104KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.07709449
105KLF5_25053715_ChIP-Seq_YYC3_Human1.07559916
106RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.07026811
107EZH2_27304074_Chip-Seq_ESCs_Mouse1.06177984
108CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.06131389
109JARID2_20075857_ChIP-Seq_MESCs_Mouse1.05620627
110NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.04051827
111NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.03535435
112* SMC4_20622854_ChIP-Seq_HELA_Human1.03482195
113ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.03395636
114SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.02269986
115POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.01410747
116KLF4_18555785_ChIP-Seq_MESCs_Mouse1.01176525
117ESR1_15608294_ChIP-ChIP_MCF-7_Human1.01133348
118RXR_22108803_ChIP-Seq_LS180_Human1.00451975
119DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.00428328
120MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.00191416
121TET1_21490601_ChIP-Seq_MESCs_Mouse0.99939966
122GBX2_23144817_ChIP-Seq_PC3_Human0.99307759
123SOX2_20726797_ChIP-Seq_SW620_Human0.98696112
124NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.98256586
125CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.97769199
126EZH2_27294783_Chip-Seq_ESCs_Mouse0.97383295
127AR_19668381_ChIP-Seq_PC3_Human0.97244921
128CDX2_20551321_ChIP-Seq_CACO-2_Human0.96713398
129KDM2B_26808549_Chip-Seq_SUP-B15_Human0.96501610
130CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.96440923
131RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.96019137
132* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.95914832
133P63_26484246_Chip-Seq_KERATINOCYTES_Human0.95161046
134BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.95060827
135EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.94777593
136* TP53_23651856_ChIP-Seq_MEFs_Mouse0.94130316
137SMC1_22415368_ChIP-Seq_MEFs_Mouse0.93628658
138AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.93459883
139DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.93427719
140RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.93240607
141AR_21909140_ChIP-Seq_LNCAP_Human0.92742294
142P300_27058665_Chip-Seq_ZR-75-30cells_Human0.92637643
143JARID2_20064375_ChIP-Seq_MESCs_Mouse0.92408017
144TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.90890703
145TP53_20018659_ChIP-ChIP_R1E_Mouse0.90397824
146TBX20_22328084_ChIP-Seq_HEART_Mouse0.90081316
147TBX20_22080862_ChIP-Seq_HEART_Mouse0.90081316
148PCGF2_27294783_Chip-Seq_NPCs_Mouse0.89917317
149ZFP281_27345836_Chip-Seq_ESCs_Mouse0.89895384
150SALL4_18804426_ChIP-ChIP_XEN_Mouse0.89635331
151NFIB_24661679_ChIP-Seq_LUNG_Mouse0.89592123
152FOXA2_19822575_ChIP-Seq_HepG2_Human0.89008115
153IRF8_27001747_Chip-Seq_BMDM_Mouse0.88906507
154TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.88887030
155TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.88674514
156TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.88165115
157SMAD4_21741376_ChIP-Seq_HESCs_Human0.88053296
158NR3C1_21868756_ChIP-Seq_MCF10A_Human0.87602391
159SUZ12_27294783_Chip-Seq_ESCs_Mouse0.87262737
160FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.87234324
161SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.87129728
162AR_21572438_ChIP-Seq_LNCaP_Human0.86764476
163CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.86760445
164JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.86519614
165TP53_18474530_ChIP-ChIP_U2OS_Human0.86275324
166SOX2_21211035_ChIP-Seq_LN229_Gbm0.86029643

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010234_abnormal_vibrissa_follicle4.17970827
2MP0008438_abnormal_cutaneous_collagen3.78081106
3MP0000569_abnormal_digit_pigmentation3.45659160
4MP0005257_abnormal_intraocular_pressure3.22030553
5MP0005409_darkened_coat_color2.85554285
6MP0003045_fibrosis2.69364629
7MP0003283_abnormal_digestive_organ2.65863695
8MP0002877_abnormal_melanocyte_morpholog2.48554087
9MP0005623_abnormal_meninges_morphology2.44209894
10MP0003705_abnormal_hypodermis_morpholog2.41636400
11MP0004272_abnormal_basement_membrane2.33073056
12MP0005248_abnormal_Harderian_gland2.23355341
13MP0003172_abnormal_lysosome_physiology2.22841737
14MP0005058_abnormal_lysosome_morphology2.18694364
15MP0005275_abnormal_skin_tensile2.13224016
16MP0001958_emphysema2.12620559
17MP0003183_abnormal_peptide_metabolism2.11974349
18MP0003566_abnormal_cell_adhesion2.11586492
19MP0008961_abnormal_basal_metabolism2.05309951
20MP0010678_abnormal_skin_adnexa2.02125981
21MP0000566_synostosis2.01901971
22MP0000537_abnormal_urethra_morphology2.00957195
23MP0000579_abnormal_nail_morphology1.99289886
24MP0006054_spinal_hemorrhage1.85856857
25MP0004233_abnormal_muscle_weight1.82796672
26MP0003303_peritoneal_inflammation1.82157177
27MP0003091_abnormal_cell_migration1.73009854
28MP0004264_abnormal_extraembryonic_tissu1.71979042
29MP0003329_amyloid_beta_deposits1.69354856
30MP0000383_abnormal_hair_follicle1.63373264
31MP0003191_abnormal_cellular_cholesterol1.57436369
32MP0003279_aneurysm1.53955986
33MP0000733_abnormal_muscle_development1.52743917
34MP0009053_abnormal_anal_canal1.49231513
35MP0005167_abnormal_blood-brain_barrier1.46191047
36MP0001348_abnormal_lacrimal_gland1.45707162
37MP0005451_abnormal_body_composition1.42067116
38MP0002060_abnormal_skin_morphology1.41161236
39MP0003941_abnormal_skin_development1.37454361
40MP0001299_abnormal_eye_distance/1.36790215
41MP0002089_abnormal_postnatal_growth/wei1.35805841
42MP0002896_abnormal_bone_mineralization1.35092534
43MP0009384_cardiac_valve_regurgitation1.32217946
44MP0004185_abnormal_adipocyte_glucose1.31683940
45MP0009840_abnormal_foam_cell1.30946349
46MP0000462_abnormal_digestive_system1.30124817
47MP0000003_abnormal_adipose_tissue1.30010362
48MP0010368_abnormal_lymphatic_system1.29633722
49MP0004130_abnormal_muscle_cell1.28998722
50MP0005501_abnormal_skin_physiology1.26736888
51MP0004858_abnormal_nervous_system1.26148329
52MP0005375_adipose_tissue_phenotype1.25974781
53MP0001346_abnormal_lacrimal_gland1.24960382
54MP0000534_abnormal_ureter_morphology1.24888920
55MP0005076_abnormal_cell_differentiation1.24269867
56MP0000428_abnormal_craniofacial_morphol1.24255476
57MP0003300_gastrointestinal_ulcer1.24167835
58MP0003453_abnormal_keratinocyte_physiol1.21948042
59MP0001502_abnormal_circadian_rhythm1.21670973
60MP0005508_abnormal_skeleton_morphology1.20104542
61MP0002168_other_aberrant_phenotype1.20016463
62MP0008260_abnormal_autophagy1.19514308
63MP0005503_abnormal_tendon_morphology1.15476623
64MP0002998_abnormal_bone_remodeling1.14621606
65MP0002090_abnormal_vision1.14024158
66MP0001849_ear_inflammation1.13612573
67MP0005666_abnormal_adipose_tissue1.12700735
68MP0002295_abnormal_pulmonary_circulatio1.11988864
69MP0003942_abnormal_urinary_system1.10949147
70MP0010352_gastrointestinal_tract_polyps1.09304338
71MP0001216_abnormal_epidermal_layer1.06630499
72MP0004782_abnormal_surfactant_physiolog1.06414558
73MP0002234_abnormal_pharynx_morphology1.04912687
74MP0003950_abnormal_plasma_membrane1.03299610
75MP0005670_abnormal_white_adipose1.02158757
76MP0000858_altered_metastatic_potential1.01279367
77MP0000767_abnormal_smooth_muscle1.01229933
78MP0010386_abnormal_urinary_bladder0.99531964
79MP0001915_intracranial_hemorrhage0.99202591
80MP0004084_abnormal_cardiac_muscle0.98857745
81MP0000678_abnormal_parathyroid_gland0.96485384
82MP0003634_abnormal_glial_cell0.95749567
83MP0003755_abnormal_palate_morphology0.95024328
84MP0009780_abnormal_chondrocyte_physiolo0.93395397
85MP0002796_impaired_skin_barrier0.90682779
86MP0000627_abnormal_mammary_gland0.90629491
87MP0010030_abnormal_orbit_morphology0.90176634
88MP0000516_abnormal_urinary_system0.90146592
89MP0005367_renal/urinary_system_phenotyp0.90146592
90MP0003385_abnormal_body_wall0.90026804
91MP0010630_abnormal_cardiac_muscle0.88518174
92MP0002254_reproductive_system_inflammat0.87600503
93MP0000647_abnormal_sebaceous_gland0.87288161
94MP0000013_abnormal_adipose_tissue0.87176789
95MP0002108_abnormal_muscle_morphology0.86547593
96MP0004510_myositis0.86545508
97MP0008775_abnormal_heart_ventricle0.85876578
98MP0005621_abnormal_cell_physiology0.85588472
99MP0000604_amyloidosis0.83983135
100MP0000778_abnormal_nervous_system0.82799532
101MP0003935_abnormal_craniofacial_develop0.82438908
102MP0000751_myopathy0.80934451
103MP0009672_abnormal_birth_weight0.80517557
104MP0002092_abnormal_eye_morphology0.80503058
105MP0003115_abnormal_respiratory_system0.79651679
106MP0005197_abnormal_uvea_morphology0.79610391
107MP0009278_abnormal_bone_marrow0.79435113
108MP0006138_congestive_heart_failure0.78742328
109MP0003690_abnormal_glial_cell0.78650887
110MP0000377_abnormal_hair_follicle0.78561195
111MP0002098_abnormal_vibrissa_morphology0.77665999
112MP0003448_altered_tumor_morphology0.77420280
113MP0000467_abnormal_esophagus_morphology0.77224023
114MP0000432_abnormal_head_morphology0.77179713
115MP0005390_skeleton_phenotype0.74294898
116MP0004947_skin_inflammation0.72751982
117MP0004087_abnormal_muscle_fiber0.72680409
118MP0000762_abnormal_tongue_morphology0.72615316
119MP0002086_abnormal_extraembryonic_tissu0.72460767
120MP0002697_abnormal_eye_size0.72109375
121MP0000747_muscle_weakness0.71204314
122MP0001614_abnormal_blood_vessel0.70189464
123MP0005023_abnormal_wound_healing0.69979724
124MP0001533_abnormal_skeleton_physiology0.69178205
125MP0002249_abnormal_larynx_morphology0.69167376
126MP0000750_abnormal_muscle_regeneration0.68795629
127MP0000759_abnormal_skeletal_muscle0.68547727
128MP0003937_abnormal_limbs/digits/tail_de0.66889519
129MP0010771_integument_phenotype0.66850443
130MP0002116_abnormal_craniofacial_bone0.66684047
131MP0009931_abnormal_skin_appearance0.66171992
132MP0001243_abnormal_dermal_layer0.65720616
133MP0002113_abnormal_skeleton_development0.65210860
134MP0004134_abnormal_chest_morphology0.64563182
135MP0000163_abnormal_cartilage_morphology0.64007433
136MP0002115_abnormal_skeleton_extremities0.63986778
137MP0002925_abnormal_cardiovascular_devel0.63709138
138MP0002653_abnormal_ependyma_morphology0.63655886
139MP0003632_abnormal_nervous_system0.62216199

Predicted human phenotypes

RankGene SetZ-score
1Premature rupture of membranes (HP:0001788)4.40677992
2Cerebral aneurysm (HP:0004944)3.48601278
3Shallow orbits (HP:0000586)3.36395495
4Abnormality of glycosphingolipid metabolism (HP:0004343)3.33570785
5Abnormality of glycolipid metabolism (HP:0010969)3.33570785
6Abnormality of liposaccharide metabolism (HP:0010968)3.33570785
7Atrophic scars (HP:0001075)3.14683685
8Round ear (HP:0100830)2.83299391
9Vertebral compression fractures (HP:0002953)2.76761578
10Aortic dissection (HP:0002647)2.76140795
11Broad metatarsal (HP:0001783)2.70137296
12Increased cerebral lipofuscin (HP:0011813)2.67860571
13Neurofibrillary tangles (HP:0002185)2.63105811
14Protrusio acetabuli (HP:0003179)2.61765473
15Large earlobe (HP:0009748)2.58123797
16Cerebral inclusion bodies (HP:0100314)2.49130090
17Subacute progressive viral hepatitis (HP:0006572)2.47151378
18Hyporeflexia of lower limbs (HP:0002600)2.39921519
19Short nail (HP:0001799)2.37489279
20Bladder diverticulum (HP:0000015)2.36761870
21Broad face (HP:0000283)2.35603913
22Ankle contracture (HP:0006466)2.34668388
23Turricephaly (HP:0000262)2.32741872
24Spinal rigidity (HP:0003306)2.32631242
25Thin bony cortex (HP:0002753)2.31157256
26Ankyloglossia (HP:0010296)2.31126649
27Aortic aneurysm (HP:0004942)2.31038571
28Severe Myopia (HP:0011003)2.27826184
29Increased connective tissue (HP:0009025)2.25022514
30Difficulty running (HP:0009046)2.20881709
31Increased neuronal autofluorescent lipopigment (HP:0002074)2.18076706
32Abnormality of the distal phalanx of the thumb (HP:0009617)2.17575419
33Mitral regurgitation (HP:0001653)2.16425212
34Obstructive sleep apnea (HP:0002870)2.15598406
35Fragile skin (HP:0001030)2.13860029
36Distal lower limb muscle weakness (HP:0009053)2.13566570
37Right ventricular cardiomyopathy (HP:0011663)2.12706364
38Abnormality of mucopolysaccharide metabolism (HP:0011020)2.10976473
39Abnormality of polysaccharide metabolism (HP:0011012)2.10976473
40Abnormality of glycosaminoglycan metabolism (HP:0004371)2.10976473
41Asymmetry of the thorax (HP:0001555)2.10549382
42Insomnia (HP:0100785)2.07841692
43Advanced eruption of teeth (HP:0006288)2.06855200
44Peritonitis (HP:0002586)2.03598262
45Arterial tortuosity (HP:0005116)2.03394312
46Dysostosis multiplex (HP:0000943)2.03224603
47Abnormality of dentin (HP:0010299)2.01727937
48Achilles tendon contracture (HP:0001771)1.99189690
49Abnormality of oral frenula (HP:0000190)1.98393985
50Abnormality of the acetabulum (HP:0003170)1.98380368
51Aneurysm (HP:0002617)1.97801761
52Mildly elevated creatine phosphokinase (HP:0008180)1.97146838
53Scapular winging (HP:0003691)1.96814506
54Hyperextensible skin (HP:0000974)1.95776673
55Aplasia involving bones of the upper limbs (HP:0009823)1.93795123
56Aplasia of the phalanges of the hand (HP:0009802)1.93795123
57Aplasia involving bones of the extremities (HP:0009825)1.93795123
58Abnormal ossification of hand bones (HP:0005921)1.93755990
59Abnormality of carpal bone ossification (HP:0006257)1.93052913
60Abnormality of the distal phalanges of the toes (HP:0010182)1.92349289
61Type 1 muscle fiber predominance (HP:0003803)1.92024725
62Distal lower limb amyotrophy (HP:0008944)1.91946551
63Joint laxity (HP:0001388)1.90643161
64Back pain (HP:0003418)1.88799741
65Vascular tortuosity (HP:0004948)1.87761627
66Distal upper limb amyotrophy (HP:0007149)1.87668245
67Upper limb amyotrophy (HP:0009129)1.87668245
68Leiomyosarcoma (HP:0100243)1.87510417
69Uterine leiomyosarcoma (HP:0002891)1.87510417
70Difficulty climbing stairs (HP:0003551)1.86105678
71Neonatal short-limb short stature (HP:0008921)1.86098919
72Thick nail (HP:0001805)1.86072448
73Vertebral arch anomaly (HP:0008438)1.84570242
74Overgrowth (HP:0001548)1.82636959
75Aqueductal stenosis (HP:0002410)1.82321001
76Mucopolysacchariduria (HP:0008155)1.82297522
77Urinary glycosaminoglycan excretion (HP:0003541)1.82297522
78Hyperparathyroidism (HP:0000843)1.81972583
79Soft skin (HP:0000977)1.80878496
80Cervical subluxation (HP:0003308)1.80553934
81Mitral stenosis (HP:0001718)1.79636099
82Abnormality of the Achilles tendon (HP:0005109)1.79515741
83Coxa vara (HP:0002812)1.78339118
84Cupped ribs (HP:0000887)1.78165878
85Spinal cord lesions (HP:0100561)1.76276869
86Syringomyelia (HP:0003396)1.76276869
87Hand muscle atrophy (HP:0009130)1.74567068
88Congenital glaucoma (HP:0001087)1.73688952
89Bowel diverticulosis (HP:0005222)1.73631655
90Lower limb amyotrophy (HP:0007210)1.73295987
91Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.73080087
92Increased variability in muscle fiber diameter (HP:0003557)1.72709059
93Biconcave vertebral bodies (HP:0004586)1.72476312
94Long palpebral fissure (HP:0000637)1.72165902
95Patellar dislocation (HP:0002999)1.71704559
96Dilatation of the ascending aorta (HP:0005111)1.71137443
97Absent frontal sinuses (HP:0002688)1.71073598
98Ulnar bowing (HP:0003031)1.71023818
99Submucous cleft hard palate (HP:0000176)1.69375421
100Hypoplastic ischia (HP:0003175)1.68594695
101Overriding aorta (HP:0002623)1.68215641
102Stomach cancer (HP:0012126)1.67986150
103Germ cell neoplasia (HP:0100728)1.66600080
104Spondylolisthesis (HP:0003302)1.66475212
105Alopecia of scalp (HP:0002293)1.66407806
106Tibial bowing (HP:0002982)1.65209811
107Osteolytic defects of the phalanges of the hand (HP:0009771)1.64767417
108Osteolytic defects of the hand bones (HP:0009699)1.64767417
109Disproportionate tall stature (HP:0001519)1.64206086
110Abnormality of nail color (HP:0100643)1.63984585
111Hip contracture (HP:0003273)1.63820952
112Mitral valve prolapse (HP:0001634)1.63542819
113Hyperacusis (HP:0010780)1.63096279
114Abnormality of the nasal septum (HP:0000419)1.63050435
115Cone-rod dystrophy (HP:0000548)1.63043996
116Sparse lateral eyebrow (HP:0005338)1.63032776
117Renovascular hypertension (HP:0100817)1.62795635
118Spinal cord compression (HP:0002176)1.61328099
119Genu recurvatum (HP:0002816)1.60216999
120Central scotoma (HP:0000603)1.59727911
121Bronchomalacia (HP:0002780)1.59422459
122Relative macrocephaly (HP:0004482)1.59226259
123Elbow flexion contracture (HP:0002987)1.58825646
124Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.58818521
125Termporal pattern (HP:0011008)1.58633432
126Insidious onset (HP:0003587)1.58633432
127Gastrointestinal carcinoma (HP:0002672)1.58293964
128Malignant gastrointestinal tract tumors (HP:0006749)1.58293964
129Coronal craniosynostosis (HP:0004440)1.58082291
130Hammertoe (HP:0001765)1.56402401
131Limited hip movement (HP:0008800)1.56166595
132Nuclear cataract (HP:0100018)1.56122639
133Femoral bowing (HP:0002980)1.55962389
134Osteoarthritis (HP:0002758)1.55677026
135Flat acetabular roof (HP:0003180)1.55290361
136Elfin facies (HP:0004428)1.54634239
137Bell-shaped thorax (HP:0001591)1.54280715
138Centrally nucleated skeletal muscle fibers (HP:0003687)1.53627941
139Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.53412692
140Blue sclerae (HP:0000592)1.51833288
141Milia (HP:0001056)1.51500936
142Natal tooth (HP:0000695)1.49973299
143Wrist flexion contracture (HP:0001239)1.49866445
144Limited elbow extension (HP:0001377)1.48928579
145Wormian bones (HP:0002645)1.48031151
146Follicular hyperkeratosis (HP:0007502)1.47147460
147Urethral obstruction (HP:0000796)1.47110251
148Arnold-Chiari malformation (HP:0002308)1.46912602
149Abnormality of abdominal situs (HP:0011620)1.46526299
150Abdominal situs inversus (HP:0003363)1.46526299
151Renal duplication (HP:0000075)1.45524756
152Abnormality of skeletal muscle fiber size (HP:0012084)1.45446742
153Aplasia cutis congenita (HP:0001057)1.45198606

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA22.79514592
2EPHA32.74710872
3RIPK12.58298133
4SMG12.56028247
5EEF2K2.49965477
6PTK62.44209957
7TTN2.43167640
8ICK2.40177258
9FER2.26317917
10DDR22.21397792
11CDK122.20541363
12EPHB12.07228650
13LATS12.00596517
14ERN11.84185907
15PRPF4B1.80104172
16PDGFRA1.75627629
17CAMK1G1.68609200
18TAOK31.66627396
19PAK41.65760398
20CAMK1D1.63511140
21PTK21.60007247
22EPHB21.57570918
23DMPK1.53305702
24SIK11.44570686
25JAK11.44403620
26TGFBR21.43930924
27INSRR1.42550540
28NTRK21.42466408
29KSR21.41047876
30AKT31.26317019
31CDC42BPA1.25072579
32SCYL21.21300452
33MAP3K91.20122799
34CSNK1A1L1.19748879
35ARAF1.19231667
36TESK11.18924307
37BRD41.13897662
38TRIB31.11879365
39PKN21.11237250
40WNK11.09550732
41BMX1.09378646
42STK38L1.04233377
43MAP3K61.02926161
44IRAK31.02024587
45NUAK11.01987199
46PAK30.98948064
47STK380.96556035
48NEK90.96288217
49MET0.95298665
50RET0.94487953
51PDGFRB0.94084982
52CHUK0.92929965
53MAP3K140.89524324
54PRKD20.89410744
55ERBB20.89345305
56PHKG20.87726765
57PHKG10.87726765
58TNIK0.86563712
59KSR10.86382954
60FGR0.85422968
61MTOR0.84905925
62SGK30.84631785
63MAP3K100.84597297
64NEK10.83466448
65MAP3K20.82493109
66PRKD10.82349379
67MOS0.82262656
68CSK0.80138522
69NTRK10.78806640
70ROCK10.76309772
71MARK20.75869246
72PRKAA20.74626501
73PAK60.74434395
74DYRK1B0.73955955
75FRK0.72456949
76ERBB40.72118834
77MAP3K30.71385978
78PKN10.71216138
79BLK0.70869768
80TRPM70.70000196
81IRAK20.69842087
82IRAK10.69822168
83PRKAA10.67574141
84STK30.66316746
85PDPK10.65130961
86ZAK0.63486592
87GSK3A0.62691441
88CSNK1G20.61596091
89MAP3K10.61184953
90GRK10.61053495
91STK110.59612217
92LRRK20.59556627
93FGFR20.58152392
94FGFR30.57982316
95PAK20.57797449
96MAP2K30.55595428
97PIK3CG0.55353330
98FGFR40.54212283
99RPS6KB20.53881435
100LMTK20.52285496
101SRC0.52261229
102FYN0.51968761
103TYRO30.51657542
104CDK60.51437106
105PRKD30.51086483
106RPS6KA20.50261292
107MAP3K130.49903218
108LIMK10.49775871
109MAP3K80.49703383
110INSR0.49206394
111FGFR10.49129631
112MAPK70.47893316
113PRKCH0.47590342
114TAOK20.47389116
115LATS20.46915482
116CSNK1G10.46456126
117EIF2AK20.46145124
118MAP3K70.45215633
119ZAP700.45056976
120TYK20.44612916
121RPS6KC10.43910034
122RPS6KL10.43910034
123ROCK20.43670612
124STK100.43083993
125CSNK1G30.41604587
126MST1R0.41220859
127BRAF0.39567237
128MYLK0.39381223
129SGK10.39215533
130MAPK150.39180403
131AKT20.39051900
132ALK0.37839267
133SGK4940.36802155
134SGK2230.36802155
135MAPK100.36673003
136CDK90.33845378
137PRKG20.33552813
138MELK0.33423379
139NEK60.32441216
140STK240.30837583
141CLK10.29760963
142CDK150.29625149
143CDK70.28709242
144HIPK20.28571481
145CAMKK10.27032566
146YES10.26704156
147MAP2K10.25234449

Predicted pathways (KEGG)

RankGene SetZ-score
1Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.16954779
2ECM-receptor interaction_Homo sapiens_hsa045122.01904997
3Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.98980040
4Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.95336636
5Thyroid cancer_Homo sapiens_hsa052161.65237704
6Glycosaminoglycan degradation_Homo sapiens_hsa005311.59800564
7Focal adhesion_Homo sapiens_hsa045101.59450284
8Prion diseases_Homo sapiens_hsa050201.58335660
9Lysosome_Homo sapiens_hsa041421.55554780
10Dilated cardiomyopathy_Homo sapiens_hsa054141.53153745
11Protein digestion and absorption_Homo sapiens_hsa049741.51304831
12Central carbon metabolism in cancer_Homo sapiens_hsa052301.50604855
13Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.49351802
14Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.47840029
15Adherens junction_Homo sapiens_hsa045201.43352331
16Non-small cell lung cancer_Homo sapiens_hsa052231.41017386
17Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.36957751
18Type II diabetes mellitus_Homo sapiens_hsa049301.33429622
19Axon guidance_Homo sapiens_hsa043601.32802445
20Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.31277104
21Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.30206846
22Proteoglycans in cancer_Homo sapiens_hsa052051.27811178
23Neurotrophin signaling pathway_Homo sapiens_hsa047221.25471419
24Mineral absorption_Homo sapiens_hsa049781.25069141
25Amoebiasis_Homo sapiens_hsa051461.22467745
26Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.14939962
27Small cell lung cancer_Homo sapiens_hsa052221.13771850
28Sphingolipid metabolism_Homo sapiens_hsa006001.12250690
29Regulation of actin cytoskeleton_Homo sapiens_hsa048101.12004189
30Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.10315637
31Insulin signaling pathway_Homo sapiens_hsa049101.09382847
32Endometrial cancer_Homo sapiens_hsa052131.09182671
33AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.08747613
34Prolactin signaling pathway_Homo sapiens_hsa049171.06416241
35Leukocyte transendothelial migration_Homo sapiens_hsa046701.05652135
36Basal cell carcinoma_Homo sapiens_hsa052171.03281148
37MicroRNAs in cancer_Homo sapiens_hsa052061.02024773
38Hippo signaling pathway_Homo sapiens_hsa043901.02020235
39Dorso-ventral axis formation_Homo sapiens_hsa043201.00698222
40Tight junction_Homo sapiens_hsa045300.98823124
41Carbohydrate digestion and absorption_Homo sapiens_hsa049730.97944524
42Toll-like receptor signaling pathway_Homo sapiens_hsa046200.97299243
43Other glycan degradation_Homo sapiens_hsa005110.96483827
44Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.94781119
45Phosphatidylinositol signaling system_Homo sapiens_hsa040700.93542141
46mTOR signaling pathway_Homo sapiens_hsa041500.93344445
47Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.93229174
48Chronic myeloid leukemia_Homo sapiens_hsa052200.93157160
49Osteoclast differentiation_Homo sapiens_hsa043800.92550832
50Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.92007844
51Prostate cancer_Homo sapiens_hsa052150.91767258
52Toxoplasmosis_Homo sapiens_hsa051450.90447584
53Renal cell carcinoma_Homo sapiens_hsa052110.90258565
54Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.89922625
55Melanogenesis_Homo sapiens_hsa049160.88893399
56Melanoma_Homo sapiens_hsa052180.88793744
57Lysine degradation_Homo sapiens_hsa003100.88155555
58AMPK signaling pathway_Homo sapiens_hsa041520.87310068
59Viral myocarditis_Homo sapiens_hsa054160.86883355
60Vibrio cholerae infection_Homo sapiens_hsa051100.86683007
61Renin secretion_Homo sapiens_hsa049240.86572667
62Colorectal cancer_Homo sapiens_hsa052100.86108688
63Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.83787031
64Thyroid hormone synthesis_Homo sapiens_hsa049180.82935145
65PI3K-Akt signaling pathway_Homo sapiens_hsa041510.82218052
66Hedgehog signaling pathway_Homo sapiens_hsa043400.82177390
67Bladder cancer_Homo sapiens_hsa052190.81835287
68Endocytosis_Homo sapiens_hsa041440.81457738
69Rap1 signaling pathway_Homo sapiens_hsa040150.80578863
70Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.80310994
71TNF signaling pathway_Homo sapiens_hsa046680.80255836
72Phospholipase D signaling pathway_Homo sapiens_hsa040720.80141516
73Malaria_Homo sapiens_hsa051440.80053352
74Inositol phosphate metabolism_Homo sapiens_hsa005620.80020694
75Thyroid hormone signaling pathway_Homo sapiens_hsa049190.79995715
76Insulin secretion_Homo sapiens_hsa049110.78994087
77NF-kappa B signaling pathway_Homo sapiens_hsa040640.77931716
78Long-term potentiation_Homo sapiens_hsa047200.75006303
79Vascular smooth muscle contraction_Homo sapiens_hsa042700.73245874
80Ras signaling pathway_Homo sapiens_hsa040140.73127714
81Galactose metabolism_Homo sapiens_hsa000520.72689155
82Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.72543908
83Longevity regulating pathway - mammal_Homo sapiens_hsa042110.72116766
84cGMP-PKG signaling pathway_Homo sapiens_hsa040220.71841680
85Pancreatic cancer_Homo sapiens_hsa052120.71699844
86Glioma_Homo sapiens_hsa052140.71632651
87Choline metabolism in cancer_Homo sapiens_hsa052310.71390627
88Ether lipid metabolism_Homo sapiens_hsa005650.71247931
89Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.70610380
90Pancreatic secretion_Homo sapiens_hsa049720.70405838
91alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.69522531
92Adipocytokine signaling pathway_Homo sapiens_hsa049200.68250336
93Circadian rhythm_Homo sapiens_hsa047100.67842696
94Renin-angiotensin system_Homo sapiens_hsa046140.67604076
95Salmonella infection_Homo sapiens_hsa051320.67538874
96Tuberculosis_Homo sapiens_hsa051520.66627402
97GnRH signaling pathway_Homo sapiens_hsa049120.66606308
98Fat digestion and absorption_Homo sapiens_hsa049750.66510906
99ErbB signaling pathway_Homo sapiens_hsa040120.66490574
100Sphingolipid signaling pathway_Homo sapiens_hsa040710.66415511
101Notch signaling pathway_Homo sapiens_hsa043300.66122816
102Pentose phosphate pathway_Homo sapiens_hsa000300.65371816
103Acute myeloid leukemia_Homo sapiens_hsa052210.65029469
104Leishmaniasis_Homo sapiens_hsa051400.64611045
105Estrogen signaling pathway_Homo sapiens_hsa049150.64087422
106HIF-1 signaling pathway_Homo sapiens_hsa040660.63933519
107VEGF signaling pathway_Homo sapiens_hsa043700.63280363
108Phagosome_Homo sapiens_hsa041450.62202770
109Shigellosis_Homo sapiens_hsa051310.61048233
110Insulin resistance_Homo sapiens_hsa049310.60583001
111Hepatitis C_Homo sapiens_hsa051600.60469942
112Pathways in cancer_Homo sapiens_hsa052000.60153759
113Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.60128022
114Fructose and mannose metabolism_Homo sapiens_hsa000510.60036352
115Hepatitis B_Homo sapiens_hsa051610.59941769
116Oxytocin signaling pathway_Homo sapiens_hsa049210.59938664
117N-Glycan biosynthesis_Homo sapiens_hsa005100.59867297
118Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.59604652
119FoxO signaling pathway_Homo sapiens_hsa040680.59523545
120Apoptosis_Homo sapiens_hsa042100.58899890
121Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.58783086
122B cell receptor signaling pathway_Homo sapiens_hsa046620.56487908
123MAPK signaling pathway_Homo sapiens_hsa040100.56158110
124Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.55497926
125Platelet activation_Homo sapiens_hsa046110.55281846
126Gap junction_Homo sapiens_hsa045400.54655895
127Jak-STAT signaling pathway_Homo sapiens_hsa046300.53615163
128Wnt signaling pathway_Homo sapiens_hsa043100.53117191
129Measles_Homo sapiens_hsa051620.52364992
130Bile secretion_Homo sapiens_hsa049760.52042367
131Glucagon signaling pathway_Homo sapiens_hsa049220.49360726

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