GPR137B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1modulation by organism of defense response of other organism involved in symbiotic interaction (GO:06.70499048
2positive regulation by organism of defense response of other organism involved in symbiotic interact6.70499048
3modulation by symbiont of host immune response (GO:0052553)6.70499048
4positive regulation by symbiont of host defense response (GO:0052509)6.70499048
5modulation by symbiont of host defense response (GO:0052031)6.70499048
6modulation by organism of immune response of other organism involved in symbiotic interaction (GO:006.70499048
7neutrophil activation involved in immune response (GO:0002283)6.36076843
8antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.69247123
9regulation of vitamin D biosynthetic process (GO:0060556)5.24952535
10regulation of interferon-beta biosynthetic process (GO:0045357)5.18448313
11macrophage activation involved in immune response (GO:0002281)5.14716278
12negative regulation of interleukin-12 production (GO:0032695)4.71453413
13natural killer cell mediated immunity (GO:0002228)4.66175828
14natural killer cell mediated cytotoxicity (GO:0042267)4.66175828
15immunoglobulin mediated immune response (GO:0016064)4.37468759
16regulation of T-helper 1 cell differentiation (GO:0045625)4.34293178
17positive regulation of interferon-alpha production (GO:0032727)4.32886752
18response to peptidoglycan (GO:0032494)4.32627632
19granulocyte activation (GO:0036230)4.22614061
20response to host immune response (GO:0052572)4.13232165
21response to immune response of other organism involved in symbiotic interaction (GO:0052564)4.13232165
22neutrophil activation (GO:0042119)4.12121109
23respiratory burst (GO:0045730)4.10257819
24regulation of interferon-alpha production (GO:0032647)4.08227221
25positive regulation of interleukin-8 biosynthetic process (GO:0045416)4.08214380
26regulation of vitamin metabolic process (GO:0030656)4.02658697
27T-helper 1 type immune response (GO:0042088)3.97687366
28microglial cell activation (GO:0001774)3.92341192
29superoxide anion generation (GO:0042554)3.73536274
30response to host (GO:0075136)3.68292995
31response to host defenses (GO:0052200)3.68292995
32response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.68292995
33positive regulation of interferon-beta production (GO:0032728)3.66946566
34regulation of chronic inflammatory response (GO:0002676)3.64612217
35macrophage activation (GO:0042116)3.63341151
36myeloid cell activation involved in immune response (GO:0002275)3.61475645
37positive regulation of membrane protein ectodomain proteolysis (GO:0051044)3.55714254
38positive regulation of antigen processing and presentation (GO:0002579)3.54911515
39regulation of cytokine secretion involved in immune response (GO:0002739)3.54086145
40phagosome maturation (GO:0090382)3.53186666
41regulation of membrane protein ectodomain proteolysis (GO:0051043)3.51777197
42glycosphingolipid catabolic process (GO:0046479)3.50527579
43oligosaccharide catabolic process (GO:0009313)3.50108043
44hydrogen peroxide biosynthetic process (GO:0050665)3.49635209
45leukocyte mediated cytotoxicity (GO:0001909)3.43484606
46negative regulation of mast cell activation (GO:0033004)3.40515188
47positive regulation of chemokine biosynthetic process (GO:0045080)3.39772890
48regulation of mononuclear cell migration (GO:0071675)3.38822330
49response to muramyl dipeptide (GO:0032495)3.37759742
50cellular response to thyroid hormone stimulus (GO:0097067)3.36486934
51lipopolysaccharide-mediated signaling pathway (GO:0031663)3.36173411
52production of molecular mediator involved in inflammatory response (GO:0002532)3.33977569
53positive regulation of mast cell activation (GO:0033005)3.33217717
54regulation of mast cell degranulation (GO:0043304)3.32832135
55regulation of interleukin-12 production (GO:0032655)3.31935158
56regulation of chemokine biosynthetic process (GO:0045073)3.30517427
57melanin biosynthetic process (GO:0042438)3.30229795
58defense response to protozoan (GO:0042832)3.29026487
59positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)3.28681676
60regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)3.26859529
61positive regulation of mast cell degranulation (GO:0043306)3.24326075
62positive regulation of mast cell activation involved in immune response (GO:0033008)3.24326075
63B cell mediated immunity (GO:0019724)3.22609577
64positive regulation of leukocyte degranulation (GO:0043302)3.21239810
65myeloid dendritic cell activation (GO:0001773)3.18151758
66interferon-gamma-mediated signaling pathway (GO:0060333)3.17490974
67regulation of mast cell activation involved in immune response (GO:0033006)3.17188277
68positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.15880988
69dendritic cell differentiation (GO:0097028)3.15155741
70glycolipid catabolic process (GO:0019377)3.15105306
71regulation of dendritic cell antigen processing and presentation (GO:0002604)3.14889537
72negative regulation of lipid storage (GO:0010888)3.14888657
73positive regulation of cellular amide metabolic process (GO:0034250)3.14647673
74response to protozoan (GO:0001562)3.14204530
75wound healing, spreading of epidermal cells (GO:0035313)3.10909029
76regulation of integrin-mediated signaling pathway (GO:2001044)3.10660534
77folic acid transport (GO:0015884)3.10115478
78positive regulation of heat generation (GO:0031652)3.06674816
79positive regulation of osteoclast differentiation (GO:0045672)3.06556364
80positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)3.04336410
81amino sugar catabolic process (GO:0046348)3.03897623
82regulation of mast cell activation (GO:0033003)3.03497075
83positive regulation of interleukin-12 production (GO:0032735)3.02351743
84negative regulation of nitric oxide biosynthetic process (GO:0045019)3.02209791
85positive regulation of type 2 immune response (GO:0002830)3.02134176
86lymphocyte mediated immunity (GO:0002449)3.00717669
87regulation of interleukin-12 biosynthetic process (GO:0045075)3.00492831
88response to thyroid hormone (GO:0097066)2.98805108
89endosome to pigment granule transport (GO:0043485)2.97184315
90endosome to melanosome transport (GO:0035646)2.97184315
91virion attachment to host cell (GO:0019062)2.96530616
92adhesion of symbiont to host cell (GO:0044650)2.96530616
93NIK/NF-kappaB signaling (GO:0038061)2.94136788
94regulation of cholesterol storage (GO:0010885)2.93209066
95germinal center formation (GO:0002467)2.93171626
96positive regulation of T-helper cell differentiation (GO:0045624)2.92538742
97regulation of immunoglobulin secretion (GO:0051023)2.92107015
98detection of molecule of bacterial origin (GO:0032490)2.90896645
99regulation of antigen processing and presentation (GO:0002577)2.90734538
100regulation of podosome assembly (GO:0071801)2.90682532
101negative regulation of inflammatory response to antigenic stimulus (GO:0002862)2.90339036
102positive regulation of NF-kappaB import into nucleus (GO:0042346)2.90013119
103regulation of interferon-beta production (GO:0032648)2.89835689
104type I interferon signaling pathway (GO:0060337)2.89073835
105cellular response to type I interferon (GO:0071357)2.89073835
106response to lipoprotein particle (GO:0055094)2.88497797
107reactive oxygen species biosynthetic process (GO:1903409)2.88130963
108positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.87686903
109regulation of T-helper cell differentiation (GO:0045622)2.87612251
110negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.86634434
111regulation of B cell receptor signaling pathway (GO:0050855)2.84833984
112regulation of heat generation (GO:0031650)2.83030221
113response to type I interferon (GO:0034340)2.82424666
114neutrophil mediated immunity (GO:0002446)2.81656563
115positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:00610812.81555636
116regulation of RIG-I signaling pathway (GO:0039535)2.81151048
117regulation of integrin activation (GO:0033623)2.80835758
118eosinophil chemotaxis (GO:0048245)2.80790711
119cellular response to lipopolysaccharide (GO:0071222)2.80759325
120negative regulation of cytokine production involved in immune response (GO:0002719)2.80496184
121positive regulation of T cell apoptotic process (GO:0070234)2.80344173
122ceramide catabolic process (GO:0046514)2.79089822
123autophagic vacuole fusion (GO:0000046)2.77157789
124regulation of leukocyte degranulation (GO:0043300)2.76456494
125regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)2.76020670
126negative regulation of interleukin-17 production (GO:0032700)2.75162713
127Arp2/3 complex-mediated actin nucleation (GO:0034314)2.74636729
128melanin metabolic process (GO:0006582)2.74574267
129cellular response to molecule of bacterial origin (GO:0071219)2.72876239
130regulation of interleukin-8 biosynthetic process (GO:0045414)2.71940960
131myeloid leukocyte activation (GO:0002274)2.70982157
132positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.70143826
133intracellular pH reduction (GO:0051452)2.69879413
134positive regulation of lymphocyte apoptotic process (GO:0070230)2.69464086
135positive regulation of interleukin-10 production (GO:0032733)2.68878843
136alpha-beta T cell differentiation involved in immune response (GO:0002293)2.68071395
137alpha-beta T cell activation involved in immune response (GO:0002287)2.68071395
138T cell differentiation involved in immune response (GO:0002292)2.68071395
139regulation of inflammatory response to antigenic stimulus (GO:0002861)2.68069292
140regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.67830950
141regulation of T cell tolerance induction (GO:0002664)2.67347006
142positive regulation of gamma-delta T cell activation (GO:0046645)2.67341963
143I-kappaB phosphorylation (GO:0007252)2.66140083
144secondary metabolite biosynthetic process (GO:0044550)2.65891593
145negative regulation of growth of symbiont in host (GO:0044130)2.64294949
146negative regulation of growth of symbiont involved in interaction with host (GO:0044146)2.64294949
147modulation of growth of symbiont involved in interaction with host (GO:0044144)2.64294949
148regulation of growth of symbiont in host (GO:0044126)2.64294949
149regulation of fever generation (GO:0031620)2.63498278
150regulation of nitric oxide biosynthetic process (GO:0045428)2.63320307
151regulation of early endosome to late endosome transport (GO:2000641)2.62726872
152regulation of macrophage chemotaxis (GO:0010758)2.62685071
153CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.62666492
154T-helper cell differentiation (GO:0042093)2.62666492
155pinocytosis (GO:0006907)2.61887485
156cellular response to interferon-gamma (GO:0071346)2.59715836
157monocyte chemotaxis (GO:0002548)2.58017535
158cell adhesion mediated by integrin (GO:0033627)2.57805538
159N-acetylneuraminate metabolic process (GO:0006054)2.57058286
160myeloid dendritic cell differentiation (GO:0043011)2.56920598
161regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.56917539
162membrane lipid catabolic process (GO:0046466)2.56484140
163T cell activation involved in immune response (GO:0002286)2.56008589
164sphingosine metabolic process (GO:0006670)2.55720235
165branching involved in labyrinthine layer morphogenesis (GO:0060670)2.55704352
166positive regulation of interleukin-6 production (GO:0032755)2.54410434
167regulation of type 2 immune response (GO:0002828)2.53037421
168positive regulation of nitric oxide biosynthetic process (GO:0045429)2.52722650
169positive regulation of interleukin-1 beta secretion (GO:0050718)2.51470450
170adhesion of symbiont to host (GO:0044406)2.50451843
171response to interferon-gamma (GO:0034341)2.49977144
172positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516)2.49872635

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_21731497_ChIP-ChIP_J774_Mouse6.54071923
2IRF8_22096565_ChIP-ChIP_GC-B_Human5.47330611
3Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse4.21778485
4* IRF8_27001747_Chip-Seq_BMDM_Mouse4.12263174
5SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse4.06537344
6NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.54485783
7BP1_19119308_ChIP-ChIP_Hs578T_Human3.46656645
8EGR1_19374776_ChIP-ChIP_THP-1_Human3.43097783
9MYB_21317192_ChIP-Seq_ERMYB_Mouse2.95430316
10MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.76563122
11RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.63665890
12IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.55982390
13NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.51998498
14TP63_17297297_ChIP-ChIP_HaCaT_Human2.37762338
15PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse2.27066290
16* SPI1_23547873_ChIP-Seq_NB4_Human2.22506505
17TFEB_21752829_ChIP-Seq_HELA_Human2.21564715
18NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.21007900
19SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.15956947
20BRD4_27068464_Chip-Seq_AML-cells_Mouse2.03824583
21STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.02503852
22IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.01173831
23ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.87827892
24GATA1_22025678_ChIP-Seq_K562_Human1.75668594
25STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.75564234
26CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.69706563
27CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.67569925
28TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.65593572
29RUNX_20019798_ChIP-Seq_JUKART_Human1.64992238
30* PU_27001747_Chip-Seq_BMDM_Mouse1.64468746
31SPI1_23127762_ChIP-Seq_K562_Human1.63771134
32RARG_19884340_ChIP-ChIP_MEFs_Mouse1.58581910
33PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.55622560
34TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.55525038
35SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.54769825
36STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.48225679
37SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.46953211
38CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.45601413
39STAT4_19710469_ChIP-ChIP_TH1__Mouse1.45226432
40VDR_24787735_ChIP-Seq_THP-1_Human1.44997698
41PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.42441524
42SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.40494792
43VDR_24763502_ChIP-Seq_THP-1_Human1.38372415
44LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.38286097
45STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.36393051
46CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.35910111
47TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.32363959
48RUNX1_22412390_ChIP-Seq_EML_Mouse1.31899872
49MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.31396333
50SCL_19346495_ChIP-Seq_HPC-7_Human1.30522625
51FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.25731247
52NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.25283610
53SALL4_18804426_ChIP-ChIP_XEN_Mouse1.24920544
54SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.21505605
55MYB_26560356_Chip-Seq_TH2_Human1.19122630
56ESR1_21235772_ChIP-Seq_MCF-7_Human1.18854180
57SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.17177051
58ELK3_25401928_ChIP-Seq_HUVEC_Human1.16371781
59* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.15611741
60PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.13351696
61FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.12318514
62GATA2_21666600_ChIP-Seq_HMVEC_Human1.12087578
63CREB1_15753290_ChIP-ChIP_HEK293T_Human1.11806897
64GATA3_27048872_Chip-Seq_THYMUS_Human1.11455475
65FOXM1_23109430_ChIP-Seq_U2OS_Human1.10229603
66FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.09598528
67ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.09378127
68LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.07204302
69CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.07079567
70GATA3_26560356_Chip-Seq_TH2_Human1.06438360
71NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.05337459
72NRF2_20460467_ChIP-Seq_MEFs_Mouse1.05337459
73EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.04242926
74SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.04101633
75SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.04101633
76E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.03892574
77ESR2_21235772_ChIP-Seq_MCF-7_Human1.02747798
78MYB_26560356_Chip-Seq_TH1_Human1.02081186
79GATA1_19941827_ChIP-Seq_MEL_Mouse1.02076316
80JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.97427458
81VDR_21846776_ChIP-Seq_THP-1_Human0.97024334
82* GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.96453606
83LXR_22158963_ChIP-Seq_LIVER_Mouse0.96017470
84PPAR_26484153_Chip-Seq_NCI-H1993_Human0.95696653
85FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.94617414
86MAF_26560356_Chip-Seq_TH1_Human0.93647563
87RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.93498998
88BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.93318474
89ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.92472993
90KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.92098837
91SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.91070291
92GATA2_22383799_ChIP-Seq_G1ME_Mouse0.91003887
93NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.89710609
94SMAD_19615063_ChIP-ChIP_OVARY_Human0.89198156
95EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.88550852
96JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.87681759
97THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.87420724
98KDM2B_26808549_Chip-Seq_SUP-B15_Human0.86983755
99* SOX2_20726797_ChIP-Seq_SW620_Human0.86737147
100VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.86647094
101ELK1_22589737_ChIP-Seq_MCF10A_Human0.86361279
102CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.85567364
103TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.85339183
104ATF3_27146783_Chip-Seq_COLON_Human0.85078090
105STAT1_20625510_ChIP-Seq_HELA_Human0.83949781
106E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.83895083
107GATA1_19941827_ChIP-Seq_MEL86_Mouse0.83152570
108KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.82928727
109FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.82647003
110ZNF217_24962896_ChIP-Seq_MCF-7_Human0.82352754
111PU1_27457419_Chip-Seq_LIVER_Mouse0.81763206
112GATA1_19941826_ChIP-Seq_K562_Human0.80498327
113* CDX2_19796622_ChIP-Seq_MESCs_Mouse0.80120781
114GABP_17652178_ChIP-ChIP_JURKAT_Human0.79958946
115KLF4_18555785_ChIP-Seq_MESCs_Mouse0.79507377
116FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.79339174
117* UBF1/2_26484160_Chip-Seq_HMECs_Human0.79242692
118CJUN_26792858_Chip-Seq_BT549_Human0.79202641
119SMRT_27268052_Chip-Seq_Bcells_Human0.78559434
120CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.78469407
121NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.76141451
122RXR_22158963_ChIP-Seq_LIVER_Mouse0.75855882
123JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.75010493
124TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.74716852
125AR_21909140_ChIP-Seq_LNCAP_Human0.74289362
126GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.73315082
127VDR_23849224_ChIP-Seq_CD4+_Human0.72893144
128P63_26484246_Chip-Seq_KERATINOCYTES_Human0.72439925
129SUZ12_18555785_Chip-Seq_ESCs_Mouse0.71770016
130TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.71400269
131TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.70581248
132NFIB_24661679_ChIP-Seq_LUNG_Mouse0.70400902
133CMYC_18555785_Chip-Seq_ESCs_Mouse0.68805735
134TP63_23658742_ChIP-Seq_EP156T_Human0.67761624
135SMAD1_18555785_Chip-Seq_ESCs_Mouse0.67297168
136NANOG_18555785_Chip-Seq_ESCs_Mouse0.67259106
137* MITF_21258399_ChIP-Seq_MELANOMA_Human0.66944854
138EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.66880722
139GATA2_19941826_ChIP-Seq_K562_Human0.66032844
140NMYC_18555785_Chip-Seq_ESCs_Mouse0.65921293

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005058_abnormal_lysosome_morphology5.10703161
2MP0001835_abnormal_antigen_presentation3.29816415
3MP0008260_abnormal_autophagy3.25032568
4MP0000569_abnormal_digit_pigmentation3.19226436
5MP0006082_CNS_inflammation3.16679897
6MP0003172_abnormal_lysosome_physiology3.08746764
7MP0005257_abnormal_intraocular_pressure3.06025408
8MP0003436_decreased_susceptibility_to3.02599713
9MP0009840_abnormal_foam_cell2.91938059
10MP0002419_abnormal_innate_immunity2.72367552
11MP0002139_abnormal_hepatobiliary_system2.56703146
12MP0003303_peritoneal_inflammation2.45088891
13MP0004510_myositis2.39808347
14MP0002148_abnormal_hypersensitivity_rea2.39434948
15MP0005000_abnormal_immune_tolerance2.38317986
16MP0000372_irregular_coat_pigmentation2.20753360
17MP0009785_altered_susceptibility_to2.11730984
18MP0002452_abnormal_antigen_presenting2.11231247
19MP0005167_abnormal_blood-brain_barrier2.04138922
20MP0001790_abnormal_immune_system2.03083517
21MP0005387_immune_system_phenotype2.03083517
22MP0003191_abnormal_cellular_cholesterol1.97549137
23MP0005025_abnormal_response_to1.92012544
24MP0005310_abnormal_salivary_gland1.86309931
25MP0002723_abnormal_immune_serum1.84042589
26MP0000371_diluted_coat_color1.83963967
27MP0002254_reproductive_system_inflammat1.83659085
28MP0003448_altered_tumor_morphology1.81980700
29MP0001533_abnormal_skeleton_physiology1.73880597
30MP0001819_abnormal_immune_cell1.65453504
31MP0001800_abnormal_humoral_immune1.65181421
32MP0000685_abnormal_immune_system1.63447862
33MP0002998_abnormal_bone_remodeling1.63179942
34MP0002420_abnormal_adaptive_immunity1.61340751
35MP0004947_skin_inflammation1.59019141
36MP0001958_emphysema1.57414501
37MP0010307_abnormal_tumor_latency1.54557762
38MP0003183_abnormal_peptide_metabolism1.52873402
39MP0005171_absent_coat_pigmentation1.52781140
40MP0000604_amyloidosis1.50771271
41MP0005464_abnormal_platelet_physiology1.50390125
42MP0000015_abnormal_ear_pigmentation1.48098044
43MP0009278_abnormal_bone_marrow1.47480070
44MP0008004_abnormal_stomach_pH1.46981188
45MP0009333_abnormal_splenocyte_physiolog1.46643511
46MP0000920_abnormal_myelination1.39206004
47MP0005174_abnormal_tail_pigmentation1.38636868
48MP0001845_abnormal_inflammatory_respons1.38431143
49MP0005671_abnormal_response_to1.38094681
50MP0002405_respiratory_system_inflammati1.37692694
51MP0003724_increased_susceptibility_to1.37305366
52MP0003693_abnormal_embryo_hatching1.35083470
53MP0003195_calcinosis1.33319486
54MP0005408_hypopigmentation1.33241414
55MP0003690_abnormal_glial_cell1.29563709
56MP0002877_abnormal_melanocyte_morpholog1.26585630
57MP0000858_altered_metastatic_potential1.25627167
58MP0000343_altered_response_to1.22475759
59MP0008469_abnormal_protein_level1.22278936
60MP0004782_abnormal_surfactant_physiolog1.19496157
61MP0003566_abnormal_cell_adhesion1.18251746
62MP0001853_heart_inflammation1.15507074
63MP0006054_spinal_hemorrhage1.13025638
64MP0002837_dystrophic_cardiac_calcinosis1.11599365
65MP0000716_abnormal_immune_system1.09602041
66MP0003186_abnormal_redox_activity1.09458637
67MP0003329_amyloid_beta_deposits1.07783865
68MP0001545_abnormal_hematopoietic_system1.07391858
69MP0005397_hematopoietic_system_phenotyp1.07391858
70MP0004858_abnormal_nervous_system1.02239708
71MP0001756_abnormal_urination1.02124395
72MP0001542_abnormal_bone_strength0.99664040
73MP0000689_abnormal_spleen_morphology0.98916858
74MP0008438_abnormal_cutaneous_collagen0.97616325
75MP0005390_skeleton_phenotype0.97613019
76MP0002136_abnormal_kidney_physiology0.96937048
77MP0002006_tumorigenesis0.95400287
78MP0009764_decreased_sensitivity_to0.94315948
79MP0002332_abnormal_exercise_endurance0.93919732
80MP0003075_altered_response_to0.93898677
81MP0003705_abnormal_hypodermis_morpholog0.93500082
82MP0005451_abnormal_body_composition0.92576446
83MP0003718_maternal_effect0.92374847
84MP0002398_abnormal_bone_marrow0.90957186
85MP0010386_abnormal_urinary_bladder0.90252297
86MP0005165_increased_susceptibility_to0.90063192
87MP0002138_abnormal_hepatobiliary_system0.89329518
88MP0003091_abnormal_cell_migration0.89001138
89MP0002163_abnormal_gland_morphology0.88874848
90MP0005164_abnormal_response_to0.88671379
91MP0002429_abnormal_blood_cell0.88622285
92MP0005166_decreased_susceptibility_to0.86959280
93MP0003795_abnormal_bone_structure0.86718358
94MP0003806_abnormal_nucleotide_metabolis0.85903610
95MP0005076_abnormal_cell_differentiation0.82610231
96MP0001501_abnormal_sleep_pattern0.80943003
97MP0005647_abnormal_sex_gland0.80830980
98MP0002722_abnormal_immune_system0.80424875
99MP0005197_abnormal_uvea_morphology0.79562734
100MP0002277_abnormal_respiratory_mucosa0.79268081
101MP0003828_pulmonary_edema0.78576336
102MP0010155_abnormal_intestine_physiology0.76866913
103MP0003656_abnormal_erythrocyte_physiolo0.76343110
104MP0002075_abnormal_coat/hair_pigmentati0.76188346
105MP0003633_abnormal_nervous_system0.75858420
106MP0003453_abnormal_keratinocyte_physiol0.75238840
107MP0003300_gastrointestinal_ulcer0.74964405
108MP0002095_abnormal_skin_pigmentation0.74538039
109MP0005621_abnormal_cell_physiology0.73952671
110MP0003136_yellow_coat_color0.73638919
111MP0003634_abnormal_glial_cell0.73489222
112MP0009763_increased_sensitivity_to0.73248730
113MP0003279_aneurysm0.72856537
114MP0001873_stomach_inflammation0.72845454
115MP0002933_joint_inflammation0.72201514
116MP0005395_other_phenotype0.72194131
117MP0000465_gastrointestinal_hemorrhage0.72033941
118MP0002090_abnormal_vision0.70143342
119MP0004381_abnormal_hair_follicle0.69416851
120MP0001663_abnormal_digestive_system0.68903372
121MP0008874_decreased_physiological_sensi0.68635184
122MP0009765_abnormal_xenobiotic_induced0.68190754
123MP0005075_abnormal_melanosome_morpholog0.67560045
124MP0005379_endocrine/exocrine_gland_phen0.66431330
125MP0005595_abnormal_vascular_smooth0.63469527

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)6.66244458
2Recurrent bacterial skin infections (HP:0005406)6.09853888
3Increased cerebral lipofuscin (HP:0011813)5.91016525
4Abnormality of macrophages (HP:0004311)5.61928224
5Vacuolated lymphocytes (HP:0001922)5.59962023
6Abnormality of glycolipid metabolism (HP:0010969)5.47393604
7Abnormality of liposaccharide metabolism (HP:0010968)5.47393604
8Abnormality of glycosphingolipid metabolism (HP:0004343)5.47393604
9Eczematoid dermatitis (HP:0000976)5.30408721
10Increased neuronal autofluorescent lipopigment (HP:0002074)5.24043776
11Recurrent gram-negative bacterial infections (HP:0005420)4.59012643
12Dysostosis multiplex (HP:0000943)4.49523251
13Axonal loss (HP:0003447)4.21500014
14Autoimmune thrombocytopenia (HP:0001973)4.02552015
15Neurofibrillary tangles (HP:0002185)3.97553331
16Disinhibition (HP:0000734)3.81882651
17Urinary glycosaminoglycan excretion (HP:0003541)3.72211830
18Mucopolysacchariduria (HP:0008155)3.72211830
19Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)3.65332821
20Abnormality of glycosaminoglycan metabolism (HP:0004371)3.59586699
21Abnormality of mucopolysaccharide metabolism (HP:0011020)3.59586699
22Abnormality of polysaccharide metabolism (HP:0011012)3.59586699
23Gingivitis (HP:0000230)3.58517860
24Segmental peripheral demyelination/remyelination (HP:0003481)3.55218490
25Nuclear cataract (HP:0100018)3.41663056
26Pustule (HP:0200039)3.41627949
27Chronic obstructive pulmonary disease (HP:0006510)3.31150291
28Obstructive lung disease (HP:0006536)3.31150291
29Mediastinal lymphadenopathy (HP:0100721)3.26500139
30Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)3.23575452
31Recurrent skin infections (HP:0001581)3.12543420
32Purpura (HP:0000979)2.97397948
33Osteolytic defects of the hand bones (HP:0009699)2.89957821
34Osteolytic defects of the phalanges of the hand (HP:0009771)2.89957821
35Thick nail (HP:0001805)2.89649118
36Systemic lupus erythematosus (HP:0002725)2.86916671
37Cerebral inclusion bodies (HP:0100314)2.79925034
38Myositis (HP:0100614)2.75068676
39Prostate neoplasm (HP:0100787)2.70910282
40Myocardial infarction (HP:0001658)2.69273720
41Basal ganglia calcification (HP:0002135)2.68459130
42Personality changes (HP:0000751)2.66375714
43Recurrent fungal infections (HP:0002841)2.65782969
44Loss of speech (HP:0002371)2.65781922
45Prolonged neonatal jaundice (HP:0006579)2.64936661
46Orchitis (HP:0100796)2.62959291
47Hepatosplenomegaly (HP:0001433)2.58457874
48Interstitial pulmonary disease (HP:0006530)2.57998117
49Poor head control (HP:0002421)2.50695477
50Agnosia (HP:0010524)2.50448052
51Neuronal loss in central nervous system (HP:0002529)2.47754682
52Metaphyseal irregularity (HP:0003025)2.47042521
53Retrobulbar optic neuritis (HP:0100654)2.46682641
54Optic neuritis (HP:0100653)2.46682641
55Peripheral demyelination (HP:0011096)2.44214248
56Vertebral compression fractures (HP:0002953)2.43745742
57Premature loss of primary teeth (HP:0006323)2.39273851
58Periodontitis (HP:0000704)2.36626100
59Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.36146720
60Stomatitis (HP:0010280)2.35895289
61Hemoptysis (HP:0002105)2.35115888
62Progressive visual loss (HP:0000529)2.31979720
63Keratoconjunctivitis sicca (HP:0001097)2.30989437
64Pathologic fracture (HP:0002756)2.28760067
65Supranuclear gaze palsy (HP:0000605)2.26396381
66Complement deficiency (HP:0004431)2.24323403
67Ocular albinism (HP:0001107)2.19449661
68Elevated erythrocyte sedimentation rate (HP:0003565)2.19110104
69Inappropriate behavior (HP:0000719)2.19070634
70Abnormality of the vasculature of the conjunctiva (HP:0008054)2.17519932
71Diminished motivation (HP:0000745)2.17412060
72Upper motor neuron abnormality (HP:0002127)2.17068512
73Hematochezia (HP:0002573)2.16144907
74Dementia (HP:0000726)2.15370510
75Nausea (HP:0002018)2.14131128
76Gangrene (HP:0100758)2.14006943
77Cervical subluxation (HP:0003308)2.13395506
78Aplasia/Hypoplasia of the macula (HP:0008059)2.12879094
79Keratoconjunctivitis (HP:0001096)2.12775828
80Increased IgM level (HP:0003496)2.12222031
81Tetraparesis (HP:0002273)2.11558126
82Polyneuropathy (HP:0001271)2.11020356
83Apathy (HP:0000741)2.08588745
84Amyloidosis (HP:0011034)2.08176771
85Recurrent pneumonia (HP:0006532)2.07064154
86Short nail (HP:0001799)2.05464687
87Conjunctival telangiectasia (HP:0000524)2.03101778
88J-shaped sella turcica (HP:0002680)2.02635062
89Bone pain (HP:0002653)2.02539972
90Vasculitis (HP:0002633)2.02524680
91Submucous cleft hard palate (HP:0000176)2.01895228
92Cellulitis (HP:0100658)2.01421922
93T lymphocytopenia (HP:0005403)1.99480863
94Hypoplasia of the fovea (HP:0007750)1.98885301
95Aplasia/Hypoplasia of the fovea (HP:0008060)1.98885301
96Increased serum ferritin (HP:0003281)1.94509168
97Osteomyelitis (HP:0002754)1.92297114
98Abnormality of the periventricular white matter (HP:0002518)1.91710268
99Urticaria (HP:0001025)1.91212235
100Spinal muscular atrophy (HP:0007269)1.89515706
101Abnormality of the distal phalanges of the toes (HP:0010182)1.88557059
102Glomerulonephritis (HP:0000099)1.88385402
103Premature rupture of membranes (HP:0001788)1.88008722
104Gastrointestinal stroma tumor (HP:0100723)1.87267944
105Malnutrition (HP:0004395)1.85713150
106Aplasia/Hypoplasia affecting the retina (HP:0008061)1.85027852
107Progressive neurologic deterioration (HP:0002344)1.84831940
108Recurrent viral infections (HP:0004429)1.84252206
109Juvenile onset (HP:0003621)1.82491192
110Albinism (HP:0001022)1.81903707
111Mutism (HP:0002300)1.81598245
112Spontaneous hematomas (HP:0007420)1.81524092
113Eosinophilia (HP:0001880)1.81064947
114Global brain atrophy (HP:0002283)1.79990299
115Cardiomegaly (HP:0001640)1.79537891
116Leukocytosis (HP:0001974)1.79205437
117Joint swelling (HP:0001386)1.76159236
118Cheilitis (HP:0100825)1.76063891
119Abnormality of T cell number (HP:0011839)1.75943514
120Memory impairment (HP:0002354)1.75403003
121Restrictive lung disease (HP:0002091)1.75076553
122Mesangial abnormality (HP:0001966)1.74515899
123Anorexia (HP:0002039)1.74176581
124Iris hypopigmentation (HP:0007730)1.72734736
125Bilateral sensorineural hearing impairment (HP:0008619)1.72397527
126Increased CSF protein (HP:0002922)1.72249799
127Abnormality of the fovea (HP:0000493)1.71691285
128Hypergammaglobulinemia (HP:0010702)1.69717509
129Abnormality of the basal ganglia (HP:0002134)1.68579855
130Petechiae (HP:0000967)1.67164505
131Pulmonary infiltrates (HP:0002113)1.67072785
132Tetany (HP:0001281)1.65916237
133Neurodegeneration (HP:0002180)1.63156953
134Asymmetric septal hypertrophy (HP:0001670)1.63085364
135Protuberant abdomen (HP:0001538)1.59696295

Predicted kinase interactions (KEA)

RankGene SetZ-score
1IRAK33.73005965
2RIPK43.72405242
3GRK73.50257425
4MAP3K143.48704669
5TBK13.25231926
6IRAK43.05364048
7DDR23.04726930
8NME22.79495845
9BUB12.78168563
10PBK2.72492960
11TYK22.33033370
12BLK2.31462516
13MST1R2.31401339
14PIM22.18747879
15KIT2.11171861
16EPHA22.03859465
17IKBKB2.02593088
18ADRBK21.96213250
19ARAF1.92664593
20NEK91.91241469
21MARK31.84174284
22RPS6KA41.72315364
23MAP4K11.59824313
24PLK41.57618715
25TAOK11.54911653
26ERN11.41172680
27CDC42BPA1.40707985
28CHUK1.39139764
29TGFBR21.39061389
30WEE11.36825195
31IKBKE1.36493214
32JAK31.27634514
33ABL21.26938341
34STK31.22521925
35JAK11.22438176
36PIM11.17757443
37MAP3K31.17741023
38ZAP701.15894205
39PRPF4B1.14919596
40MAP3K131.12220622
41TNK21.10537763
42CAMKK21.08838678
43FGR1.07868788
44BMX1.06808263
45TYRO31.05080795
46NEK21.01496929
47CSK1.01267295
48EPHB11.00552679
49ZAK0.99692948
50MAP3K10.99648080
51TRIB30.97721706
52PDK20.96866613
53HCK0.96514107
54PAK40.96461293
55CSF1R0.94540257
56ERBB30.93164775
57STK100.90750328
58STK240.87098897
59SCYL20.85554650
60MET0.83466533
61MST40.82995815
62MAP3K100.81917119
63DAPK20.81519810
64SYK0.81114786
65LYN0.79525024
66KSR20.78556321
67TAOK30.76909131
68PRKCD0.75085630
69IRAK10.75008384
70MOS0.74071864
71FRK0.71122516
72PKN10.69990971
73MAP2K60.69046218
74CAMK1D0.68326763
75STK40.68285430
76IRAK20.67768279
77ABL10.67656179
78PRKD30.65682097
79FER0.65205932
80MAP3K90.64003881
81PDGFRA0.62479356
82BRAF0.61771585
83TRPM70.61277889
84WNK30.60504823
85STK38L0.59251862
86MAP3K50.59022029
87MAP3K110.58412864
88BCR0.58342686
89LRRK20.57518572
90BRSK20.57420412
91MATK0.57217730
92PDK10.57128034
93CLK10.56534569
94JAK20.56523906
95PDGFRB0.56473796
96EPHA30.56417018
97MAP2K30.55485868
98MAPKAPK30.55287088
99TXK0.54724158
100BMPR20.54431620
101SIK30.54339573
102LCK0.52794208
103TAOK20.52624031
104EIF2AK30.51896426
105GSK3A0.50551492
106EGFR0.48560150
107CDK60.47993284
108MAPK70.47087255
109MAPKAPK20.46643793
110EIF2AK10.44960281
111CAMK2D0.44959034
112PDPK10.44307986
113TTN0.42344424
114EIF2AK20.42237360
115TGFBR10.41619260
116FES0.41392916
117ACVR1B0.40887753
118MAP3K80.40325021
119HIPK20.39835681
120AKT30.38220106
121SGK30.38103909
122MAP2K20.37909706
123PAK10.37901189
124PTK60.37610891
125CAMK2G0.36125971
126MAPK40.34422921
127TESK10.34007852
128CAMKK10.32970684
129INSR0.30312909
130SGK20.29991602
131PLK10.29460036
132FGFR30.28497326
133DYRK30.27859018
134ROCK20.27610459
135RIPK10.27040806
136CSNK1G30.26650850
137CSNK1G20.26149222
138PRKCQ0.24951854
139MAPK120.24500575
140CSNK1A1L0.24025463
141BTK0.23154424
142NTRK30.22823452

Predicted pathways (KEGG)

RankGene SetZ-score
1Lysosome_Homo sapiens_hsa041423.85287185
2Glycosaminoglycan degradation_Homo sapiens_hsa005312.92949517
3Leishmaniasis_Homo sapiens_hsa051402.52395314
4Rheumatoid arthritis_Homo sapiens_hsa053232.45501312
5Other glycan degradation_Homo sapiens_hsa005112.36202979
6Phagosome_Homo sapiens_hsa041452.34962812
7Collecting duct acid secretion_Homo sapiens_hsa049662.31416984
8Toll-like receptor signaling pathway_Homo sapiens_hsa046202.23368042
9Tuberculosis_Homo sapiens_hsa051522.16415227
10Osteoclast differentiation_Homo sapiens_hsa043802.14548753
11NF-kappa B signaling pathway_Homo sapiens_hsa040642.08926803
12Graft-versus-host disease_Homo sapiens_hsa053322.01590127
13Legionellosis_Homo sapiens_hsa051341.95829100
14NOD-like receptor signaling pathway_Homo sapiens_hsa046211.94287363
15Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.93773691
16Vitamin B6 metabolism_Homo sapiens_hsa007501.86427255
17Regulation of autophagy_Homo sapiens_hsa041401.86412188
18Staphylococcus aureus infection_Homo sapiens_hsa051501.83516852
19Malaria_Homo sapiens_hsa051441.69498439
20Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.66416011
21Apoptosis_Homo sapiens_hsa042101.61525540
22Pertussis_Homo sapiens_hsa051331.59539158
23Proteasome_Homo sapiens_hsa030501.56937505
24Measles_Homo sapiens_hsa051621.51157454
25Shigellosis_Homo sapiens_hsa051311.49475829
26Antigen processing and presentation_Homo sapiens_hsa046121.48464199
27Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.46636017
28Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.45739199
29Salmonella infection_Homo sapiens_hsa051321.39963976
30B cell receptor signaling pathway_Homo sapiens_hsa046621.39890784
31TNF signaling pathway_Homo sapiens_hsa046681.37991056
32Allograft rejection_Homo sapiens_hsa053301.37558568
33Sphingolipid metabolism_Homo sapiens_hsa006001.35555921
34RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.32461381
35Influenza A_Homo sapiens_hsa051641.32437095
36Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.28393570
37Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.25420317
38Toxoplasmosis_Homo sapiens_hsa051451.23427340
39Mineral absorption_Homo sapiens_hsa049781.09506425
40Asthma_Homo sapiens_hsa053101.07959052
41Epstein-Barr virus infection_Homo sapiens_hsa051691.04170364
42Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.01829771
43Intestinal immune network for IgA production_Homo sapiens_hsa046721.01679846
44Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.01280813
45Vibrio cholerae infection_Homo sapiens_hsa051100.99663669
46Hematopoietic cell lineage_Homo sapiens_hsa046400.98925855
47Steroid biosynthesis_Homo sapiens_hsa001000.97965174
48Hepatitis B_Homo sapiens_hsa051610.96741341
49Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.95753266
50Chemokine signaling pathway_Homo sapiens_hsa040620.95638216
51p53 signaling pathway_Homo sapiens_hsa041150.93464878
52Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.93386977
53Type I diabetes mellitus_Homo sapiens_hsa049400.91056407
54Herpes simplex infection_Homo sapiens_hsa051680.90579432
55Hepatitis C_Homo sapiens_hsa051600.88797012
56Leukocyte transendothelial migration_Homo sapiens_hsa046700.87810214
57Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.84813063
58Complement and coagulation cascades_Homo sapiens_hsa046100.82290116
59Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.81897765
60Endocytosis_Homo sapiens_hsa041440.81510924
61Chronic myeloid leukemia_Homo sapiens_hsa052200.79808992
62Jak-STAT signaling pathway_Homo sapiens_hsa046300.79007093
63SNARE interactions in vesicular transport_Homo sapiens_hsa041300.78808884
64Primary immunodeficiency_Homo sapiens_hsa053400.78200147
65AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.77893442
66Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.76722016
67Pancreatic cancer_Homo sapiens_hsa052120.71685756
68Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.71429412
69Small cell lung cancer_Homo sapiens_hsa052220.69089839
70Adipocytokine signaling pathway_Homo sapiens_hsa049200.68879380
71Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.68713865
72Amoebiasis_Homo sapiens_hsa051460.67765155
73Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.67489236
74African trypanosomiasis_Homo sapiens_hsa051430.62290107
75Renin-angiotensin system_Homo sapiens_hsa046140.61617984
76Renal cell carcinoma_Homo sapiens_hsa052110.60984949
77Primary bile acid biosynthesis_Homo sapiens_hsa001200.60892049
78Bladder cancer_Homo sapiens_hsa052190.59421691
79Acute myeloid leukemia_Homo sapiens_hsa052210.58493198
80RNA polymerase_Homo sapiens_hsa030200.57574665
81Vitamin digestion and absorption_Homo sapiens_hsa049770.57481706
82Dorso-ventral axis formation_Homo sapiens_hsa043200.57390626
83Neurotrophin signaling pathway_Homo sapiens_hsa047220.56778018
84Glycerophospholipid metabolism_Homo sapiens_hsa005640.56445770
85PPAR signaling pathway_Homo sapiens_hsa033200.56372234
86Sphingolipid signaling pathway_Homo sapiens_hsa040710.56246714
87FoxO signaling pathway_Homo sapiens_hsa040680.56134461
88Viral myocarditis_Homo sapiens_hsa054160.51002578
89HIF-1 signaling pathway_Homo sapiens_hsa040660.50265592
90Viral carcinogenesis_Homo sapiens_hsa052030.49042806
91VEGF signaling pathway_Homo sapiens_hsa043700.48821599
92Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.48642616
93Proteoglycans in cancer_Homo sapiens_hsa052050.47128287
94mTOR signaling pathway_Homo sapiens_hsa041500.46927479
95Inositol phosphate metabolism_Homo sapiens_hsa005620.45979547
96Prolactin signaling pathway_Homo sapiens_hsa049170.44360982
97Autoimmune thyroid disease_Homo sapiens_hsa053200.44217067
98Prostate cancer_Homo sapiens_hsa052150.44000507
99Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.43879218
100Regulation of actin cytoskeleton_Homo sapiens_hsa048100.42915455
101Folate biosynthesis_Homo sapiens_hsa007900.42890538
102Type II diabetes mellitus_Homo sapiens_hsa049300.41919652
103Platelet activation_Homo sapiens_hsa046110.41756397
104Pentose and glucuronate interconversions_Homo sapiens_hsa000400.41001245
105Synaptic vesicle cycle_Homo sapiens_hsa047210.38843804
106MicroRNAs in cancer_Homo sapiens_hsa052060.38733811
107Prion diseases_Homo sapiens_hsa050200.36731605
108Tryptophan metabolism_Homo sapiens_hsa003800.36342885
109Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.36041274
110Fructose and mannose metabolism_Homo sapiens_hsa000510.35378582
111Cell cycle_Homo sapiens_hsa041100.33489855
112T cell receptor signaling pathway_Homo sapiens_hsa046600.32171300
113Adherens junction_Homo sapiens_hsa045200.31630839
114Phospholipase D signaling pathway_Homo sapiens_hsa040720.30138717
115Sulfur metabolism_Homo sapiens_hsa009200.29098344
116Notch signaling pathway_Homo sapiens_hsa043300.25291661
117GnRH signaling pathway_Homo sapiens_hsa049120.25258644
118Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.25097600
119Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.24546868
120Caffeine metabolism_Homo sapiens_hsa002320.20964936
121Insulin resistance_Homo sapiens_hsa049310.20921622
122Transcriptional misregulation in cancer_Homo sapiens_hsa052020.19758162
123Renin secretion_Homo sapiens_hsa049240.19009273
124MAPK signaling pathway_Homo sapiens_hsa040100.18812808
125HTLV-I infection_Homo sapiens_hsa051660.16956874
126Ether lipid metabolism_Homo sapiens_hsa005650.14911812
127Estrogen signaling pathway_Homo sapiens_hsa049150.14249519

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