GPR150

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protoporphyrinogen IX metabolic process (GO:0046501)8.08509234
2protoporphyrinogen IX biosynthetic process (GO:0006782)7.77358689
3heme biosynthetic process (GO:0006783)6.10556757
4porphyrin-containing compound biosynthetic process (GO:0006779)5.99020523
5tetrapyrrole biosynthetic process (GO:0033014)5.43493867
6antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.40487872
7antigen processing and presentation of endogenous antigen (GO:0019883)5.20016957
8antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.12390860
9regulation of female receptivity (GO:0045924)5.10612222
10female mating behavior (GO:0060180)4.91141195
11positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.87934161
12erythrocyte maturation (GO:0043249)4.83945841
13positive regulation of gamma-delta T cell activation (GO:0046645)4.68909731
14heme metabolic process (GO:0042168)4.66462877
15mature B cell differentiation involved in immune response (GO:0002313)4.66253998
16synaptic vesicle exocytosis (GO:0016079)4.64929834
17aggressive behavior (GO:0002118)4.62798564
18negative thymic T cell selection (GO:0045060)4.59061376
19negative T cell selection (GO:0043383)4.56403785
20protein localization to synapse (GO:0035418)4.55243942
21porphyrin-containing compound metabolic process (GO:0006778)4.52888910
22DNA deamination (GO:0045006)4.52092096
23hyperosmotic salinity response (GO:0042538)4.38147624
24antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.37485925
25positive regulation of antigen processing and presentation (GO:0002579)4.22890888
26regulation of B cell receptor signaling pathway (GO:0050855)4.21960399
27neurotransmitter-gated ion channel clustering (GO:0072578)4.17781407
28regulation of dendritic cell antigen processing and presentation (GO:0002604)4.16497306
29sleep (GO:0030431)4.10979512
30synaptic vesicle docking involved in exocytosis (GO:0016081)3.98972542
31positive thymic T cell selection (GO:0045059)3.96430119
32regulation of short-term neuronal synaptic plasticity (GO:0048172)3.95783230
33mucosal-associated lymphoid tissue development (GO:0048537)3.94157310
34Peyers patch development (GO:0048541)3.94157310
35erythrocyte development (GO:0048821)3.93840180
36regulation of penile erection (GO:0060405)3.92290407
37regulation of synaptic vesicle exocytosis (GO:2000300)3.89372270
38negative regulation of cell killing (GO:0031342)3.88755675
39negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.88755675
40regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.87074733
41glutamate secretion (GO:0014047)3.84348439
42mature B cell differentiation (GO:0002335)3.81799990
43positive regulation of synapse maturation (GO:0090129)3.80796770
44regulation of synaptic vesicle transport (GO:1902803)3.75304001
45hemoglobin metabolic process (GO:0020027)3.75069670
46positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.72177572
47maternal behavior (GO:0042711)3.70613003
48grooming behavior (GO:0007625)3.70017295
49synaptic vesicle maturation (GO:0016188)3.68431857
50amino sugar catabolic process (GO:0046348)3.66448633
51thymic T cell selection (GO:0045061)3.65950637
52immunoglobulin mediated immune response (GO:0016064)3.65173702
53regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.63764838
54positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.63036994
55vocalization behavior (GO:0071625)3.63018392
56positive regulation of neurotransmitter secretion (GO:0001956)3.53354825
57response to insecticide (GO:0017085)3.51497748
58neuron cell-cell adhesion (GO:0007158)3.51113958
59regulation of antigen processing and presentation (GO:0002577)3.50842813
60parental behavior (GO:0060746)3.45819370
61deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.45017324
62positive regulation of prostaglandin secretion (GO:0032308)3.44886494
63positive T cell selection (GO:0043368)3.43892371
64locomotory exploration behavior (GO:0035641)3.41850812
65regulation of gamma-delta T cell differentiation (GO:0045586)3.41707580
66regulation of prostaglandin secretion (GO:0032306)3.39155370
67regulation of B cell differentiation (GO:0045577)3.38996934
68T cell migration (GO:0072678)3.38606540
69positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.38230977
70negative regulation of erythrocyte differentiation (GO:0045647)3.35928923
71positive regulation of B cell differentiation (GO:0045579)3.34402948
72positive regulation of uterine smooth muscle contraction (GO:0070474)3.31186542
73purine deoxyribonucleotide catabolic process (GO:0009155)3.30123389
74regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.28056612
75detection of bacterium (GO:0016045)3.27061772
76regulation of synapse maturation (GO:0090128)3.26667241
77regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.26545183
78regulation of RIG-I signaling pathway (GO:0039535)3.26530919
79purine-containing compound salvage (GO:0043101)3.25410806
80NIK/NF-kappaB signaling (GO:0038061)3.23491151
81postsynaptic membrane organization (GO:0001941)3.22794223
82T cell selection (GO:0045058)3.22201244
83purine nucleotide salvage (GO:0032261)3.21675897
84regulation of glutamate receptor signaling pathway (GO:1900449)3.20852623
85mast cell activation (GO:0045576)3.17637731
86regulation of T cell receptor signaling pathway (GO:0050856)3.16854983
87B cell receptor signaling pathway (GO:0050853)3.16635178
88regulation of gamma-delta T cell activation (GO:0046643)3.16105539
89L-fucose metabolic process (GO:0042354)3.13726138
90L-fucose catabolic process (GO:0042355)3.13726138
91fucose catabolic process (GO:0019317)3.13726138
92positive regulation of neurotransmitter transport (GO:0051590)3.12930095
93regulation of isotype switching to IgG isotypes (GO:0048302)3.08135338
94response to methylmercury (GO:0051597)3.07875159
95neurotransmitter secretion (GO:0007269)3.06662459
96leukocyte aggregation (GO:0070486)3.06222202
97detection of other organism (GO:0098543)3.05396776
98response to interleukin-15 (GO:0070672)3.05256301
99positive regulation of fibroblast migration (GO:0010763)3.04903436
100glycine transport (GO:0015816)3.03230662
101proline transport (GO:0015824)3.02865444
102transferrin transport (GO:0033572)3.01289081
103regulation of alpha-beta T cell proliferation (GO:0046640)2.99562333
104positive regulation of T cell differentiation in thymus (GO:0033089)2.98043667
105membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.97774630
106response to auditory stimulus (GO:0010996)2.96200084
107positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.94878216
108positive regulation of membrane potential (GO:0045838)2.94547422
109mechanosensory behavior (GO:0007638)2.94484807
110tetrapyrrole metabolic process (GO:0033013)2.89915586
111positive regulation of interleukin-2 production (GO:0032743)2.89756906
112oligosaccharide catabolic process (GO:0009313)2.88878443
113glucosamine-containing compound catabolic process (GO:1901072)2.88016288
114regulation of protein heterodimerization activity (GO:0043497)2.87660307
115positive regulation of alpha-beta T cell proliferation (GO:0046641)2.86755870
116pigment biosynthetic process (GO:0046148)2.85770364
117tolerance induction (GO:0002507)2.85769156
118gamma-aminobutyric acid signaling pathway (GO:0007214)2.85018286
119negative regulation of microtubule polymerization (GO:0031115)2.83893665
120ribosomal small subunit assembly (GO:0000028)2.82597002
121interferon-gamma-mediated signaling pathway (GO:0060333)2.80010718
122negative regulation of bone resorption (GO:0045779)2.79347442
123regulation of T cell mediated cytotoxicity (GO:0001914)2.79009322
124exploration behavior (GO:0035640)2.77444098
125histamine secretion (GO:0001821)2.77148906
126positive regulation of T cell differentiation (GO:0045582)2.76029604
127positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.73388545
128regulation of interleukin-2 biosynthetic process (GO:0045076)2.73287130
129ferric iron transport (GO:0015682)2.71812455
130trivalent inorganic cation transport (GO:0072512)2.71812455
131positive regulation of T cell mediated cytotoxicity (GO:0001916)2.70395403
132antigen receptor-mediated signaling pathway (GO:0050851)2.69728575
133myeloid cell development (GO:0061515)2.69228100
134regulation of T-helper 1 cell differentiation (GO:0045625)2.68505904
135neurotransmitter transport (GO:0006836)2.68063830
136G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.66884874
137neuromuscular process controlling posture (GO:0050884)2.66529112
138JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.65913419
139negative regulation of interleukin-12 production (GO:0032695)2.64673439
140regulation of dopamine uptake involved in synaptic transmission (GO:0051584)2.64568020
141regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)2.64568020
142negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.64492327
143regulation of synapse structural plasticity (GO:0051823)2.64025261
144leukocyte homeostasis (GO:0001776)2.64017527
145glutamate receptor signaling pathway (GO:0007215)2.63848336
146negative regulation of leukocyte mediated immunity (GO:0002704)2.63571612
147T cell receptor signaling pathway (GO:0050852)2.63329283
148cellular potassium ion homeostasis (GO:0030007)2.63326758
149regulation of monocyte differentiation (GO:0045655)2.63304437
150actin filament capping (GO:0051693)2.63163062
151G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.62579839
152regulation of glutamate secretion (GO:0014048)2.61712968
153mast cell degranulation (GO:0043303)2.60844377
154mast cell activation involved in immune response (GO:0002279)2.60844377
155regulation of regulatory T cell differentiation (GO:0045589)2.60305602
156type I interferon signaling pathway (GO:0060337)2.59556070
157cellular response to type I interferon (GO:0071357)2.59556070
158negative regulation of innate immune response (GO:0045824)2.58895543
159bone resorption (GO:0045453)2.58881525
160positive regulation of lymphocyte differentiation (GO:0045621)2.58306547
161T cell costimulation (GO:0031295)2.58241846
162negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.56450941
163regulation of neurotransmitter secretion (GO:0046928)2.55134565
164response to type I interferon (GO:0034340)2.54915911
165B cell mediated immunity (GO:0019724)2.54844176
166fucosylation (GO:0036065)2.54334820
167lymphocyte costimulation (GO:0031294)2.54111197
168synaptic transmission, glutamatergic (GO:0035249)2.53648888
169positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.53625238
170neuron-neuron synaptic transmission (GO:0007270)2.53624974
171ionotropic glutamate receptor signaling pathway (GO:0035235)2.53518281
172positive regulation of B cell proliferation (GO:0030890)2.53359206
173regulation of synaptic transmission, glutamatergic (GO:0051966)2.52782592
174positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516)2.52691148
175sodium ion export (GO:0071436)2.49945782
176G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.49676015
177long-term synaptic potentiation (GO:0060291)2.49573537
178activation of protein kinase A activity (GO:0034199)2.49483017
179deoxyribose phosphate biosynthetic process (GO:0046385)2.49445153
1802-deoxyribonucleotide biosynthetic process (GO:0009265)2.49445153
181neutral amino acid transport (GO:0015804)2.48268418
182long-term memory (GO:0007616)2.47578005
183DNA replication initiation (GO:0006270)2.46810255
184cerebellar granule cell differentiation (GO:0021707)2.45928094
185presynaptic membrane assembly (GO:0097105)2.45815149
186positive regulation of synaptic transmission, GABAergic (GO:0032230)2.45040469
187energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.43568710
188ATP hydrolysis coupled proton transport (GO:0015991)2.43568710
189histamine transport (GO:0051608)2.41784288
190neuronal action potential propagation (GO:0019227)2.40884758
191synaptic vesicle transport (GO:0048489)2.39947261
192establishment of synaptic vesicle localization (GO:0097480)2.39947261
193neurotransmitter uptake (GO:0001504)2.38791744
194synaptic vesicle endocytosis (GO:0048488)2.36766220
195auditory behavior (GO:0031223)2.36748868
196regulation of neurotransmitter transport (GO:0051588)2.34140776

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.76160482
2IRF8_22096565_ChIP-ChIP_GC-B_Human5.32848145
3* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.88717820
4FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.45916738
5STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.80839325
6KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse3.29537872
7IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.26797981
8RUNX_20019798_ChIP-Seq_JUKART_Human3.19424702
9BP1_19119308_ChIP-ChIP_Hs578T_Human3.09475628
10NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.05494091
11GATA1_22025678_ChIP-Seq_K562_Human2.97018215
12* IRF8_21731497_ChIP-ChIP_J774_Mouse2.88449791
13GATA1_19941827_ChIP-Seq_MEL_Mouse2.85889420
14SCL_19346495_ChIP-Seq_HPC-7_Human2.71149214
15MYB_26560356_Chip-Seq_TH2_Human2.66417103
16MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.54311479
17NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.52830512
18TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse2.48179845
19MAF_26560356_Chip-Seq_TH1_Human2.45371605
20* IRF8_27001747_Chip-Seq_BMDM_Mouse2.37968003
21* UTX_26944678_Chip-Seq_JUKART_Human2.35439811
22* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.34200258
23VDR_24763502_ChIP-Seq_THP-1_Human2.32198255
24REST_21632747_ChIP-Seq_MESCs_Mouse2.31751958
25LYL1_20887958_ChIP-Seq_HPC-7_Mouse2.29530779
26STAT4_19710469_ChIP-ChIP_TH1__Mouse2.28279992
27MYB_26560356_Chip-Seq_TH1_Human2.26275766
28HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.24533694
29* MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.23977976
30GATA1_19941826_ChIP-Seq_K562_Human2.22428447
31FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.18169172
32E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.16699927
33GBX2_23144817_ChIP-Seq_PC3_Human2.16175058
34EZH2_22144423_ChIP-Seq_EOC_Human2.11246694
35RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.10193144
36* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.08875902
37REST_18959480_ChIP-ChIP_MESCs_Mouse2.07801467
38MAF_26560356_Chip-Seq_TH2_Human2.03815676
39STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.01337306
40SPI1_23547873_ChIP-Seq_NB4_Human2.01154879
41VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.98020359
42THAP11_20581084_ChIP-Seq_MESCs_Mouse1.96625760
43ESR1_15608294_ChIP-ChIP_MCF-7_Human1.95432978
44NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.90414527
45FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.87255551
46MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.85681095
47MYC_18555785_ChIP-Seq_MESCs_Mouse1.79746809
48BRD4_27068464_Chip-Seq_AML-cells_Mouse1.79595323
49E2F4_17652178_ChIP-ChIP_JURKAT_Human1.76338103
50GATA3_27048872_Chip-Seq_THYMUS_Human1.74826386
51IKZF1_21737484_ChIP-ChIP_HCT116_Human1.73642654
52TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.73443552
53HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.72708954
54LXR_22292898_ChIP-Seq_THP-1_Human1.71869907
55MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.71758714
56KDM2B_26808549_Chip-Seq_SUP-B15_Human1.70736782
57* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.68684859
58KDM2B_26808549_Chip-Seq_DND41_Human1.67323938
59LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.64843961
60SRF_21415370_ChIP-Seq_HL-1_Mouse1.64207537
61GATA2_19941826_ChIP-Seq_K562_Human1.63217286
62MYB_21317192_ChIP-Seq_ERMYB_Mouse1.62766183
63SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.58863726
64SPI1_23127762_ChIP-Seq_K562_Human1.57209911
65KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.56995955
66* SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.56279962
67SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.54777354
68CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.53674810
69KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.52756294
70BCL6_27268052_Chip-Seq_Bcells_Human1.52113446
71* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.51025175
72GATA2_21666600_ChIP-Seq_HMVEC_Human1.48315224
73TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.45264758
74KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.44301657
75TCF7_22412390_ChIP-Seq_EML_Mouse1.39841420
76ERG_20887958_ChIP-Seq_HPC-7_Mouse1.39822466
77PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.39468461
78JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.39335173
79ELK3_25401928_ChIP-Seq_HUVEC_Human1.39034942
80* JARID2_20064375_ChIP-Seq_MESCs_Mouse1.38176933
81ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.36811459
82DNAJC2_21179169_ChIP-ChIP_NT2_Human1.35436773
83EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.34793672
84GATA3_26560356_Chip-Seq_TH2_Human1.32756066
85RARB_27405468_Chip-Seq_BRAIN_Mouse1.32654962
86TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.30746919
87HOXB4_20404135_ChIP-ChIP_EML_Mouse1.29691030
88CTBP2_25329375_ChIP-Seq_LNCAP_Human1.29391285
89VDR_24787735_ChIP-Seq_THP-1_Human1.28916736
90PU.1_20513432_ChIP-Seq_Bcells_Mouse1.28015243
91ETS1_20019798_ChIP-Seq_JURKAT_Human1.26509909
92HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.23819513
93Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.23555189
94CTCF_18555785_ChIP-Seq_MESCs_Mouse1.23505964
95YY1_21170310_ChIP-Seq_MESCs_Mouse1.23068016
96* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.22986845
97PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.19509762
98VDR_23849224_ChIP-Seq_CD4+_Human1.17910682
99THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.17301876
100GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.16502301
101FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.16140623
102SA1_27219007_Chip-Seq_ERYTHROID_Human1.15340535
103CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.14596440
104CTCF_26484167_Chip-Seq_Bcells_Mouse1.13540868
105EST1_17652178_ChIP-ChIP_JURKAT_Human1.13192587
106CTBP1_25329375_ChIP-Seq_LNCAP_Human1.11735099
107PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.10748703
108BCOR_27268052_Chip-Seq_Bcells_Human1.09849049
109RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.09116971
110SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.08867458
111ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.08451335
112GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.08155484
113CTCF_27219007_Chip-Seq_ERYTHROID_Human1.07944167
114SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.07817342
115GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.05909745
116IGF1R_20145208_ChIP-Seq_DFB_Human1.05536659
117FOXM1_23109430_ChIP-Seq_U2OS_Human1.04964515
118CIITA_25753668_ChIP-Seq_RAJI_Human1.04863592
119TET1_21451524_ChIP-Seq_MESCs_Mouse1.03732758
120RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.03440115
121FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.02805647
122CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.02066428
123IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.01517582
124SPI1_20517297_ChIP-Seq_HL60_Human1.00798905
125* CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.00355706
126* MTF2_20144788_ChIP-Seq_MESCs_Mouse0.98821996
127KDM2B_26808549_Chip-Seq_JURKAT_Human0.98559722
128CTCF_21964334_Chip-Seq_Bcells_Human0.98236521
129SUZ12_27294783_Chip-Seq_ESCs_Mouse0.97862751
130GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97859543
131VDR_21846776_ChIP-Seq_THP-1_Human0.97834169
132SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.97638775
133TAF15_26573619_Chip-Seq_HEK293_Human0.97140678
134SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.96891039
135RARG_19884340_ChIP-ChIP_MEFs_Mouse0.96204895
136RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.95892512
137CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.95829413
138SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.95731027
139CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.95564365
140MYC_19079543_ChIP-ChIP_MESCs_Mouse0.95377635
141VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.94864595
142JARID2_20075857_ChIP-Seq_MESCs_Mouse0.94456082
143ELF1_20517297_ChIP-Seq_JURKAT_Human0.94079819
144CTCF_21964334_ChIP-Seq_BJAB-B_Human0.93983990
145* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.92609033
146EGR1_19374776_ChIP-ChIP_THP-1_Human0.90765138
147FUS_26573619_Chip-Seq_HEK293_Human0.90666930
148CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.90367436
149P68_20966046_ChIP-Seq_HELA_Human0.90215326
150GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.90151593
151* SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.90124657
152CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.89562693
153FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.89356900
154MYC_19030024_ChIP-ChIP_MESCs_Mouse0.88465824
155* EZH2_27294783_Chip-Seq_ESCs_Mouse0.88044767
156PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.87756068
157E2F1_18555785_ChIP-Seq_MESCs_Mouse0.87738100
158SRY_22984422_ChIP-ChIP_TESTIS_Rat0.87648363
159MYC_22102868_ChIP-Seq_BL_Human0.87106213
160* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.86458812
161* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.86325849
162RUNX1_22412390_ChIP-Seq_EML_Mouse0.86084147
163ELF1_17652178_ChIP-ChIP_JURKAT_Human0.84204404
164ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.83939698
165FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.83573718
166XRN2_22483619_ChIP-Seq_HELA_Human0.83474591
167GATA2_22383799_ChIP-Seq_G1ME_Mouse0.81916948
168RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.81915502
169ETS1_22383799_ChIP-Seq_G1ME_Mouse0.81809989
170E2F1_21310950_ChIP-Seq_MCF-7_Human0.81781133
171FOXP3_21729870_ChIP-Seq_TREG_Human0.81393580

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003656_abnormal_erythrocyte_physiolo5.44662016
2MP0004147_increased_porphyrin_level5.02097219
3MP0001835_abnormal_antigen_presentation4.32347158
4MP0004859_abnormal_synaptic_plasticity4.15615523
5MP0003880_abnormal_central_pattern3.59407913
6MP0003724_increased_susceptibility_to3.22028405
7MP0003763_abnormal_thymus_physiology3.01256095
8MP0001968_abnormal_touch/_nociception3.00281120
9MP0002735_abnormal_chemical_nociception2.94877326
10MP0002736_abnormal_nociception_after2.94713584
11MP0003635_abnormal_synaptic_transmissio2.89754253
12MP0005000_abnormal_immune_tolerance2.86579473
13MP0003436_decreased_susceptibility_to2.78985570
14MP0001800_abnormal_humoral_immune2.74186020
15MP0009046_muscle_twitch2.65142970
16MP0005310_abnormal_salivary_gland2.63078349
17MP0000013_abnormal_adipose_tissue2.60505754
18MP0001790_abnormal_immune_system2.50130912
19MP0005387_immune_system_phenotype2.50130912
20MP0002723_abnormal_immune_serum2.49678483
21MP0004270_analgesia2.46953948
22MP0009745_abnormal_behavioral_response2.46689447
23MP0002452_abnormal_antigen_presenting2.45226322
24MP0002734_abnormal_mechanical_nocicepti2.45182999
25MP0002419_abnormal_innate_immunity2.45127731
26MP0002420_abnormal_adaptive_immunity2.39497855
27MP0001819_abnormal_immune_cell2.36894276
28MP0002064_seizures2.36025239
29MP0000465_gastrointestinal_hemorrhage2.26003490
30MP0002063_abnormal_learning/memory/cond2.18130452
31MP0003879_abnormal_hair_cell2.16142776
32MP0000604_amyloidosis2.12786566
33MP0002272_abnormal_nervous_system1.96367284
34MP0009333_abnormal_splenocyte_physiolog1.93395657
35MP0010386_abnormal_urinary_bladder1.92398565
36MP0002733_abnormal_thermal_nociception1.91566924
37MP0001529_abnormal_vocalization1.84832466
38MP0001970_abnormal_pain_threshold1.83255603
39MP0003303_peritoneal_inflammation1.82943586
40MP0002067_abnormal_sensory_capabilities1.82773000
41MP0003183_abnormal_peptide_metabolism1.82531321
42MP0000716_abnormal_immune_system1.81223378
43MP0009785_altered_susceptibility_to1.80129588
44MP0005058_abnormal_lysosome_morphology1.76975250
45MP0002572_abnormal_emotion/affect_behav1.70721073
46MP0008004_abnormal_stomach_pH1.70628005
47MP0009278_abnormal_bone_marrow1.66602394
48MP0000689_abnormal_spleen_morphology1.65718402
49MP0009379_abnormal_foot_pigmentation1.61042139
50MP0001533_abnormal_skeleton_physiology1.59596843
51MP0006276_abnormal_autonomic_nervous1.58397300
52MP0004142_abnormal_muscle_tone1.58083256
53MP0001853_heart_inflammation1.58011771
54MP0002405_respiratory_system_inflammati1.57761449
55MP0000372_irregular_coat_pigmentation1.57253948
56MP0000703_abnormal_thymus_morphology1.54248570
57MP0010155_abnormal_intestine_physiology1.49232251
58MP0005075_abnormal_melanosome_morpholog1.47213397
59MP0004947_skin_inflammation1.46110827
60MP0001845_abnormal_inflammatory_respons1.44493496
61MP0005646_abnormal_pituitary_gland1.44221693
62MP0005397_hematopoietic_system_phenotyp1.43892355
63MP0001545_abnormal_hematopoietic_system1.43892355
64MP0004811_abnormal_neuron_physiology1.41701344
65MP0002998_abnormal_bone_remodeling1.40506109
66MP0001986_abnormal_taste_sensitivity1.40138749
67MP0001188_hyperpigmentation1.39671899
68MP0006082_CNS_inflammation1.38940181
69MP0008569_lethality_at_weaning1.36907210
70MP0002184_abnormal_innervation1.34840354
71MP0006036_abnormal_mitochondrial_physio1.34751533
72MP0003329_amyloid_beta_deposits1.34742789
73MP0005423_abnormal_somatic_nervous1.33342482
74MP0001440_abnormal_grooming_behavior1.27669836
75MP0000681_abnormal_thyroid_gland1.25726095
76MP0003111_abnormal_nucleus_morphology1.25210088
77MP0008260_abnormal_autophagy1.20876937
78MP0002396_abnormal_hematopoietic_system1.20793009
79MP0002822_catalepsy1.18742983
80MP0001905_abnormal_dopamine_level1.18586459
81MP0008872_abnormal_physiological_respon1.16184369
82MP0001486_abnormal_startle_reflex1.14648469
83MP0001502_abnormal_circadian_rhythm1.14344755
84MP0001501_abnormal_sleep_pattern1.14320175
85MP0003300_gastrointestinal_ulcer1.12992698
86MP0002876_abnormal_thyroid_physiology1.12742126
87MP0002557_abnormal_social/conspecific_i1.10582587
88MP0002933_joint_inflammation1.09627645
89MP0005464_abnormal_platelet_physiology1.07816307
90MP0005174_abnormal_tail_pigmentation1.07705583
91MP0005636_abnormal_mineral_homeostasis1.07681460
92MP0001348_abnormal_lacrimal_gland1.07346202
93MP0003075_altered_response_to1.06933949
94MP0002166_altered_tumor_susceptibility1.06398448
95MP0008469_abnormal_protein_level1.05997093
96MP0009840_abnormal_foam_cell1.05584228
97MP0005551_abnormal_eye_electrophysiolog1.04884693
98MP0009780_abnormal_chondrocyte_physiolo1.04073662
99MP0004130_abnormal_muscle_cell1.02858692
100MP0003787_abnormal_imprinting1.02340373
101MP0002398_abnormal_bone_marrow1.00960246
102MP0004924_abnormal_behavior1.00472748
103MP0005386_behavior/neurological_phenoty1.00472748
104MP0000858_altered_metastatic_potential0.99610341
105MP0002138_abnormal_hepatobiliary_system0.99305717
106MP0010094_abnormal_chromosome_stability0.99080236
107MP0000490_abnormal_crypts_of0.97928735
108MP0005671_abnormal_response_to0.97015437
109MP0002909_abnormal_adrenal_gland0.96949354
110MP0001851_eye_inflammation0.96769826
111MP0005535_abnormal_body_temperature0.96404746
112MP0000569_abnormal_digit_pigmentation0.94191766
113MP0001663_abnormal_digestive_system0.94110302
114MP0002006_tumorigenesis0.93967222
115MP0008874_decreased_physiological_sensi0.93879616
116MP0009764_decreased_sensitivity_to0.93387214
117MP0002066_abnormal_motor_capabilities/c0.92785462
118MP0002090_abnormal_vision0.91635211
119MP0000955_abnormal_spinal_cord0.91207565
120MP0006035_abnormal_mitochondrial_morpho0.90202272
121MP0006292_abnormal_olfactory_placode0.89179934
122MP0005165_increased_susceptibility_to0.87689217
123MP0005166_decreased_susceptibility_to0.87606155
124MP0005645_abnormal_hypothalamus_physiol0.84479405
125MP0002882_abnormal_neuron_morphology0.84246382
126MP0003191_abnormal_cellular_cholesterol0.83820415
127MP0003172_abnormal_lysosome_physiology0.83753478
128MP0000685_abnormal_immune_system0.82685038
129MP0002638_abnormal_pupillary_reflex0.82590970
130MP0005390_skeleton_phenotype0.82209241
131MP0003866_abnormal_defecation0.81506479
132MP0000003_abnormal_adipose_tissue0.80680158
133MP0004808_abnormal_hematopoietic_stem0.80225815
134MP0002148_abnormal_hypersensitivity_rea0.80018798
135MP0000015_abnormal_ear_pigmentation0.79329473
136MP0003633_abnormal_nervous_system0.78516881
137MP0002095_abnormal_skin_pigmentation0.77756255
138MP0000631_abnormal_neuroendocrine_gland0.77245759
139MP0005167_abnormal_blood-brain_barrier0.75885297
140MP0002429_abnormal_blood_cell0.72543590
141MP0002751_abnormal_autonomic_nervous0.70901975
142MP0009763_increased_sensitivity_to0.70677600
143MP0005451_abnormal_body_composition0.70513557
144MP0004215_abnormal_myocardial_fiber0.70511175
145MP0002722_abnormal_immune_system0.70101590
146MP0005083_abnormal_biliary_tract0.69997558
147MP0002229_neurodegeneration0.68230871
148MP0004858_abnormal_nervous_system0.67527693
149MP0003221_abnormal_cardiomyocyte_apopto0.65805403
150MP0008058_abnormal_DNA_repair0.65496606
151MP0003795_abnormal_bone_structure0.65115044
152MP0001873_stomach_inflammation0.65037706
153MP0002019_abnormal_tumor_incidence0.64535060
154MP0008877_abnormal_DNA_methylation0.63870804
155MP0000249_abnormal_blood_vessel0.63559316
156MP0001764_abnormal_homeostasis0.63481171
157MP0003631_nervous_system_phenotype0.62748548
158MP0002163_abnormal_gland_morphology0.62041433
159MP0000358_abnormal_cell_content/0.60936823
160MP0005025_abnormal_response_to0.60936505
161MP0001765_abnormal_ion_homeostasis0.60839621
162MP0004145_abnormal_muscle_electrophysio0.59389975
163MP0003828_pulmonary_edema0.57550075
164MP0003448_altered_tumor_morphology0.56195392
165MP0004510_myositis0.55409101
166MP0005085_abnormal_gallbladder_physiolo0.54217495
167MP0001727_abnormal_embryo_implantation0.52966542

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the heme biosynthetic pathway (HP:0010472)8.90637622
2Poikilocytosis (HP:0004447)6.16804612
3Abnormality of liposaccharide metabolism (HP:0010968)5.37602476
4Abnormality of glycosphingolipid metabolism (HP:0004343)5.37602476
5Abnormality of glycolipid metabolism (HP:0010969)5.37602476
6Stomatitis (HP:0010280)5.22945985
7Focal motor seizures (HP:0011153)4.42239287
8Acanthocytosis (HP:0001927)4.38069939
9Increased IgM level (HP:0003496)4.31429666
10Abnormal delayed hypersensitivity skin test (HP:0002963)4.03221807
11Visual hallucinations (HP:0002367)4.02935510
12Panhypogammaglobulinemia (HP:0003139)3.94342795
13Agammaglobulinemia (HP:0004432)3.72758087
14Reticulocytosis (HP:0001923)3.70598637
15Recurrent fungal infections (HP:0002841)3.66849263
16Increased cerebral lipofuscin (HP:0011813)3.61567395
17IgG deficiency (HP:0004315)3.59920181
18Elevated erythrocyte sedimentation rate (HP:0003565)3.56747973
19Autoimmune thrombocytopenia (HP:0001973)3.56455400
20Epileptic encephalopathy (HP:0200134)3.54073783
21Autoimmune hemolytic anemia (HP:0001890)3.51933237
22Abnormal number of erythroid precursors (HP:0012131)3.48382609
23Recurrent viral infections (HP:0004429)3.47695227
24Fatigue (HP:0012378)3.46651166
25Abnormality of B cell number (HP:0010975)3.45945167
26Abnormality of T cells (HP:0002843)3.40610450
27Eczematoid dermatitis (HP:0000976)3.40331385
28Xerostomia (HP:0000217)3.37616704
29Abnormality of T cell physiology (HP:0011840)3.32039105
30T lymphocytopenia (HP:0005403)3.32005125
31Papilledema (HP:0001085)3.29805046
32Abnormality of T cell number (HP:0011839)3.27439633
33Dysostosis multiplex (HP:0000943)3.26412453
34Focal seizures (HP:0007359)3.20526358
35Prostate neoplasm (HP:0100787)3.15935592
36Hepatocellular necrosis (HP:0001404)3.11703759
37Abnormality of cells of the erythroid lineage (HP:0012130)3.11389740
38Myokymia (HP:0002411)3.06976812
39Stomach cancer (HP:0012126)3.05476382
40Severe combined immunodeficiency (HP:0004430)3.01199163
41Generalized tonic-clonic seizures (HP:0002069)2.99898929
42B lymphocytopenia (HP:0010976)2.99691179
43Thrombocytosis (HP:0001894)2.96130070
44Hypergammaglobulinemia (HP:0010702)2.92276318
45Abnormal mitochondria in muscle tissue (HP:0008316)2.91796406
46Abnormality of reticulocytes (HP:0004312)2.89221172
47Combined immunodeficiency (HP:0005387)2.87980313
48Agitation (HP:0000713)2.83792983
49Mutism (HP:0002300)2.81252787
50Febrile seizures (HP:0002373)2.77316791
51Pustule (HP:0200039)2.77225297
52Delusions (HP:0000746)2.75469755
53Acute necrotizing encephalopathy (HP:0006965)2.74762484
54Abnormality of macrophages (HP:0004311)2.73057293
55Petechiae (HP:0000967)2.71155403
56Leukocytosis (HP:0001974)2.68328031
57Aplastic anemia (HP:0001915)2.67563223
58Mitochondrial inheritance (HP:0001427)2.64435828
59Granulocytopenia (HP:0001913)2.62986733
60Dialeptic seizures (HP:0011146)2.61154119
61Absent rod-and cone-mediated responses on ERG (HP:0007688)2.60832349
62Meningitis (HP:0001287)2.58468595
63IgM deficiency (HP:0002850)2.58116914
64Myositis (HP:0100614)2.56688042
65Cholelithiasis (HP:0001081)2.55679840
66Depression (HP:0000716)2.54656358
67Hyperbilirubinemia (HP:0002904)2.54022830
68Progressive macrocephaly (HP:0004481)2.53981674
69Loss of speech (HP:0002371)2.53217226
70Abnormality of mucopolysaccharide metabolism (HP:0011020)2.51124411
71Abnormality of polysaccharide metabolism (HP:0011012)2.51124411
72Abnormality of glycosaminoglycan metabolism (HP:0004371)2.51124411
73Colitis (HP:0002583)2.50314378
74IgA deficiency (HP:0002720)2.47380603
75Gastrointestinal inflammation (HP:0004386)2.47179663
76Absence seizures (HP:0002121)2.46650040
77Gaze-evoked nystagmus (HP:0000640)2.46522335
78Cutaneous photosensitivity (HP:0000992)2.42028804
79Spondylolisthesis (HP:0003302)2.41638807
80Hepatic necrosis (HP:0002605)2.40966079
81Mediastinal lymphadenopathy (HP:0100721)2.40601735
82Inflammation of the large intestine (HP:0002037)2.40371126
83Insomnia (HP:0100785)2.40332163
84Recurrent abscess formation (HP:0002722)2.39874557
85Pulmonary fibrosis (HP:0002206)2.39410974
86Eosinophilia (HP:0001880)2.39234894
87Protruding tongue (HP:0010808)2.37540381
88Polygenic inheritance (HP:0010982)2.37407783
89Recurrent bacterial skin infections (HP:0005406)2.37105166
90Pallor (HP:0000980)2.35682354
91Diplopia (HP:0000651)2.34249263
92Abnormality of binocular vision (HP:0011514)2.34249263
93Gingival bleeding (HP:0000225)2.33864934
94Urinary glycosaminoglycan excretion (HP:0003541)2.33493567
95Mucopolysacchariduria (HP:0008155)2.33493567
96Abnormal gallbladder morphology (HP:0012437)2.32685946
97Increased IgE level (HP:0003212)2.32013584
98Anxiety (HP:0000739)2.31549917
99Hyperventilation (HP:0002883)2.30492347
100Pulmonary infiltrates (HP:0002113)2.30238214
101Abnormality of the prostate (HP:0008775)2.29059366
102Chronic diarrhea (HP:0002028)2.27407978
103Truncal ataxia (HP:0002078)2.26970515
104Papilloma (HP:0012740)2.24937927
105Verrucae (HP:0200043)2.24937927
106Gait imbalance (HP:0002141)2.22514853
107Lymphopenia (HP:0001888)2.22489438
108Atonic seizures (HP:0010819)2.22015873
109Vasculitis (HP:0002633)2.21330676
110Increased intramyocellular lipid droplets (HP:0012240)2.20824224
111Impaired smooth pursuit (HP:0007772)2.20720114
112Increased CSF lactate (HP:0002490)2.20364628
113Epistaxis (HP:0000421)2.19856410
114Recurrent bronchitis (HP:0002837)2.19826321
115Episodic fever (HP:0001954)2.19582101
116Thoracic kyphosis (HP:0002942)2.19091289
117Cortical visual impairment (HP:0100704)2.16562926
118Spontaneous hematomas (HP:0007420)2.16054595
119Abnormality of cells of the lymphoid lineage (HP:0012140)2.14082985
120Obstructive lung disease (HP:0006536)2.10815262
121Chronic obstructive pulmonary disease (HP:0006510)2.10815262
122Purpura (HP:0000979)2.10560898
123Hypochromic microcytic anemia (HP:0004840)2.09734391
124Osteomalacia (HP:0002749)2.09538022
125Paralysis (HP:0003470)2.07843194
126Abnormality of eosinophils (HP:0001879)2.07503676
127Acute encephalopathy (HP:0006846)2.06983917
128Gastrointestinal stroma tumor (HP:0100723)2.06669426
129Neurodegeneration (HP:0002180)2.06572919
130Recurrent skin infections (HP:0001581)2.05933142
131Postural instability (HP:0002172)2.05811099
132Acute lymphatic leukemia (HP:0006721)2.05122752
133Abnormal hair whorl (HP:0010721)2.05121024
134Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.03958309
135Decreased activity of mitochondrial respiratory chain (HP:0008972)2.03958309
136Impaired vibration sensation in the lower limbs (HP:0002166)2.02496933
137Hypothermia (HP:0002045)2.01770773
138Progressive neurologic deterioration (HP:0002344)2.00270299
139Urticaria (HP:0001025)1.98506316
140Vacuolated lymphocytes (HP:0001922)1.97697926
141Broad-based gait (HP:0002136)1.96442978
142Hypertensive crisis (HP:0100735)1.95361505
143Recurrent lower respiratory tract infections (HP:0002783)1.94022356
144Progressive cerebellar ataxia (HP:0002073)1.93218578
145Increased hepatocellular lipid droplets (HP:0006565)1.92305324
146Genetic anticipation (HP:0003743)1.92166662
147Recurrent gram-negative bacterial infections (HP:0005420)1.91327557
148Supranuclear gaze palsy (HP:0000605)1.90978334
149Psychosis (HP:0000709)1.88589770
150Abnormal rod and cone electroretinograms (HP:0008323)1.88442765
151Systemic lupus erythematosus (HP:0002725)1.88352524
152Abnormality of ocular smooth pursuit (HP:0000617)1.87764500
153Chest pain (HP:0100749)1.87020632
154Diaphragmatic weakness (HP:0009113)1.86238486
155Limb ataxia (HP:0002070)1.85930166
156Increased serum lactate (HP:0002151)1.85843542
157Constricted visual fields (HP:0001133)1.85272598
158Encephalitis (HP:0002383)1.84927279
159Urethral obstruction (HP:0000796)1.83089249
160Birth length less than 3rd percentile (HP:0003561)1.82563618
161Congenital primary aphakia (HP:0007707)1.82367509
162Large eyes (HP:0001090)1.82310406
163Hydroureter (HP:0000072)1.81908261
164Poor eye contact (HP:0000817)1.81902913
165Amaurosis fugax (HP:0100576)1.81845049
166Microretrognathia (HP:0000308)1.81042199
167Prolonged bleeding time (HP:0003010)1.81026220
168Lactic acidosis (HP:0003128)1.81022942
169Poor suck (HP:0002033)1.80341143
170Increased muscle lipid content (HP:0009058)1.80245642
171Limb dystonia (HP:0002451)1.76831026
172Nephrogenic diabetes insipidus (HP:0009806)1.76569700
173Medial flaring of the eyebrow (HP:0010747)1.76456577
174Cholecystitis (HP:0001082)1.73054138
175Abnormal gallbladder physiology (HP:0012438)1.73054138
176Microcytic anemia (HP:0001935)1.72466157
177Macrocytic anemia (HP:0001972)1.72297001
178Cellulitis (HP:0100658)1.71402451
179Dysmetric saccades (HP:0000641)1.70638347
180Abnormal eating behavior (HP:0100738)1.69763410
181Emotional lability (HP:0000712)1.69507658
182Increased neuronal autofluorescent lipopigment (HP:0002074)1.68815765
183Recurrent cutaneous fungal infections (HP:0011370)1.66185302
184Chronic mucocutaneous candidiasis (HP:0002728)1.66185302
185Abnormality of alanine metabolism (HP:0010916)1.65351116
186Hyperalaninemia (HP:0003348)1.65351116
187Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.65351116
188Unsteady gait (HP:0002317)1.64288051
189Polyphagia (HP:0002591)1.64116041

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK4.15995027
2CDK193.92757134
3FLT33.01832675
4TLK12.95708812
5MAP3K122.91156364
6DAPK22.84686983
7DAPK12.67662531
8SCYL22.58234808
9CCNB12.56863781
10STK162.48787862
11EIF2AK12.37672665
12MAP3K132.34203753
13NME22.15340010
14ACVR1B2.11009432
15PRPF4B2.08666749
16PLK22.05047005
17MAP2K72.03777502
18KIT2.03501584
19MARK11.99357826
20PRKD31.90063526
21MAP3K141.86660364
22NEK91.83862069
23GRK51.82317572
24NEK21.82260888
25MATK1.80570851
26TAOK31.77783594
27KDR1.75665596
28TNIK1.72770735
29MINK11.71881838
30TESK21.69960502
31VRK11.67241125
32EEF2K1.64811655
33CAMKK21.56501219
34IKBKB1.51626508
35MAP2K31.50585462
36BRSK11.50404840
37BUB11.50030238
38MAP3K41.47453934
39JAK31.46766409
40EPHA41.46578046
41NTRK31.46033617
42FES1.43140459
43CSF1R1.43134841
44BTK1.43097365
45TYK21.42667766
46RIPK41.38755136
47ITK1.36512196
48ZAP701.33964253
49MAPK131.32703528
50SYK1.31782453
51IKBKE1.31101752
52MAPKAPK31.28655685
53MAPKAPK51.24479125
54CAMKK11.23070327
55MAPK71.17171386
56BCKDK1.15706029
57CDC71.14949453
58PRKD21.12919172
59MAP3K91.12148563
60LCK1.12010784
61GRK71.08380524
62MAP2K21.07693723
63IRAK31.04754136
64GRK60.98679690
65NEK10.98153106
66EIF2AK30.97489080
67PRKCH0.97175403
68TNK20.96261841
69PLK40.95661098
70BMPR1B0.94303806
71HCK0.89537837
72MAP2K40.89109898
73SIK20.88704719
74BLK0.88703713
75AKT30.85821718
76TGFBR10.85267916
77DAPK30.84584848
78CDK50.81467777
79MAP3K30.79180165
80NTRK20.78751441
81RPS6KL10.78392061
82RPS6KC10.78392061
83MAP3K60.78214401
84TEC0.77275738
85TSSK60.76459231
86ADRBK20.75721277
87CSK0.72648508
88ADRBK10.72290735
89TAOK20.70178907
90MAP3K10.68894879
91PRKCQ0.68416251
92SIK30.67672480
93RPS6KA60.67383520
94PRKCG0.65795403
95OXSR10.64878902
96BRAF0.63802823
97PIK3CG0.62600292
98JAK10.62223836
99CDK180.62182898
100CDK140.61949315
101BMPR20.61484272
102ERN10.60746511
103CAMK10.60279440
104CDK150.59924310
105CDK11A0.58907185
106DYRK20.57912552
107EIF2AK20.57830274
108CDC42BPA0.57155070
109STK40.55956538
110BRSK20.55559594
111UHMK10.54618319
112PKN20.54191895
113TESK10.52422648
114PIM20.51304023
115MAPK40.50903618
116MUSK0.47933238
117DYRK30.46759932
118PASK0.46628911
119MAPK120.44821742
120PIM10.44800122
121MAP4K10.42114644
122IRAK40.41017866
123SGK20.40837513
124TRPM70.38773865
125RET0.38239231
126ARAF0.38194854
127YES10.38009660
128PLK30.37208555
129CDK80.37084793
130PAK20.36576470
131MAP2K10.36196849
132AURKA0.35778692
133DYRK1B0.35315108
134LYN0.35101496
135SGK4940.34960142
136SGK2230.34960142
137NTRK10.34201867
138FGR0.32991451
139ABL20.32603847
140KSR20.31832408
141SGK30.31224221
142MAP3K110.31018514
143TAOK10.30613019
144WEE10.29726690
145NUAK10.29661659
146JAK20.29367195
147SIK10.29324844
148PAK60.28028347
149TGFBR20.27927128
150IRAK20.27729496
151PTK2B0.27557680
152INSR0.27093099
153LIMK10.27017927
154CDK40.26167295
155CLK10.26044931
156HIPK20.24447968
157PINK10.23729268
158TXK0.23609510
159MAPK110.23406934
160CHEK20.22792676
161RPS6KA20.22518329
162TBK10.22304698
163NME10.20857791

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053404.62766782
2Synaptic vesicle cycle_Homo sapiens_hsa047213.90093044
3Allograft rejection_Homo sapiens_hsa053303.61309756
4Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008603.38474175
5Autoimmune thyroid disease_Homo sapiens_hsa053203.28917835
6Intestinal immune network for IgA production_Homo sapiens_hsa046723.16517194
7Graft-versus-host disease_Homo sapiens_hsa053322.91031679
8Nicotine addiction_Homo sapiens_hsa050332.90411193
9Collecting duct acid secretion_Homo sapiens_hsa049662.83992751
10Asthma_Homo sapiens_hsa053102.76544258
11DNA replication_Homo sapiens_hsa030302.50485408
12Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.35406000
13Morphine addiction_Homo sapiens_hsa050322.34061088
14Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006042.31517879
15Olfactory transduction_Homo sapiens_hsa047402.26341689
16B cell receptor signaling pathway_Homo sapiens_hsa046622.25222542
17Other glycan degradation_Homo sapiens_hsa005112.22148846
18Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.19817046
19Antigen processing and presentation_Homo sapiens_hsa046122.19022150
20GABAergic synapse_Homo sapiens_hsa047272.09773726
21Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.08303697
22Leishmaniasis_Homo sapiens_hsa051402.02014429
23RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.00890071
24Osteoclast differentiation_Homo sapiens_hsa043801.96149310
25Lysosome_Homo sapiens_hsa041421.95139318
26T cell receptor signaling pathway_Homo sapiens_hsa046601.87874702
27Circadian entrainment_Homo sapiens_hsa047131.86117997
28NF-kappa B signaling pathway_Homo sapiens_hsa040641.82026093
29Insulin secretion_Homo sapiens_hsa049111.81105316
30Alcoholism_Homo sapiens_hsa050341.80472654
31Viral myocarditis_Homo sapiens_hsa054161.80281163
32Oxidative phosphorylation_Homo sapiens_hsa001901.78456843
33Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.72187798
34Long-term potentiation_Homo sapiens_hsa047201.69447815
35Staphylococcus aureus infection_Homo sapiens_hsa051501.68505055
36Salivary secretion_Homo sapiens_hsa049701.63104388
37Glutamatergic synapse_Homo sapiens_hsa047241.58619630
38Amphetamine addiction_Homo sapiens_hsa050311.57010216
39Systemic lupus erythematosus_Homo sapiens_hsa053221.54370890
40Dopaminergic synapse_Homo sapiens_hsa047281.51159524
41Malaria_Homo sapiens_hsa051441.47596799
42Parkinsons disease_Homo sapiens_hsa050121.44914228
43Toll-like receptor signaling pathway_Homo sapiens_hsa046201.44835536
44Ribosome_Homo sapiens_hsa030101.44556014
45Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.44161954
46Cholinergic synapse_Homo sapiens_hsa047251.41642506
47Measles_Homo sapiens_hsa051621.36741781
48Herpes simplex infection_Homo sapiens_hsa051681.36472535
49SNARE interactions in vesicular transport_Homo sapiens_hsa041301.36108682
50Vibrio cholerae infection_Homo sapiens_hsa051101.33473672
51Aldosterone synthesis and secretion_Homo sapiens_hsa049251.32899268
52Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.32588208
53Toxoplasmosis_Homo sapiens_hsa051451.27634653
54Shigellosis_Homo sapiens_hsa051311.19099063
55Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.17133442
56Serotonergic synapse_Homo sapiens_hsa047261.17084893
57Acute myeloid leukemia_Homo sapiens_hsa052211.13914265
58Alzheimers disease_Homo sapiens_hsa050101.08725435
59Calcium signaling pathway_Homo sapiens_hsa040201.06902895
60Mismatch repair_Homo sapiens_hsa034301.05923688
61Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.04624756
62Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.03997667
63Oocyte meiosis_Homo sapiens_hsa041141.03072043
64Gastric acid secretion_Homo sapiens_hsa049711.02326984
65TNF signaling pathway_Homo sapiens_hsa046681.01644279
66Cocaine addiction_Homo sapiens_hsa050301.01599648
67Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.01253916
68Long-term depression_Homo sapiens_hsa047301.00203108
69Influenza A_Homo sapiens_hsa051640.98737444
70Taste transduction_Homo sapiens_hsa047420.97600995
71Huntingtons disease_Homo sapiens_hsa050160.97012811
72Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.95795354
73Pyrimidine metabolism_Homo sapiens_hsa002400.95411573
74Proteasome_Homo sapiens_hsa030500.94699460
75Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.92005220
76Glioma_Homo sapiens_hsa052140.90930578
77Pertussis_Homo sapiens_hsa051330.90191991
78Oxytocin signaling pathway_Homo sapiens_hsa049210.89091228
79Renin secretion_Homo sapiens_hsa049240.88574348
80Gap junction_Homo sapiens_hsa045400.88505481
81Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.88158838
82Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.87975566
83Cardiac muscle contraction_Homo sapiens_hsa042600.81778568
84Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.81426674
85Jak-STAT signaling pathway_Homo sapiens_hsa046300.81308636
86Phagosome_Homo sapiens_hsa041450.80737011
87Homologous recombination_Homo sapiens_hsa034400.80395173
88Purine metabolism_Homo sapiens_hsa002300.76422387
89Cell cycle_Homo sapiens_hsa041100.76039736
90Epstein-Barr virus infection_Homo sapiens_hsa051690.76004669
91Neurotrophin signaling pathway_Homo sapiens_hsa047220.73102560
92Nucleotide excision repair_Homo sapiens_hsa034200.72839920
93Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.71385853
94Cyanoamino acid metabolism_Homo sapiens_hsa004600.70569642
95N-Glycan biosynthesis_Homo sapiens_hsa005100.69964622
96Rheumatoid arthritis_Homo sapiens_hsa053230.68804629
97Prolactin signaling pathway_Homo sapiens_hsa049170.67951185
98Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.66362098
99Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.65451738
100Sulfur metabolism_Homo sapiens_hsa009200.64064847
101GnRH signaling pathway_Homo sapiens_hsa049120.62983634
102Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.62836290
103Non-small cell lung cancer_Homo sapiens_hsa052230.61699398
104Leukocyte transendothelial migration_Homo sapiens_hsa046700.58856463
105Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.58245193
106Transcriptional misregulation in cancer_Homo sapiens_hsa052020.57974192
107Hepatitis C_Homo sapiens_hsa051600.56346579
108Endocytosis_Homo sapiens_hsa041440.55046400
109HTLV-I infection_Homo sapiens_hsa051660.54690686
110Base excision repair_Homo sapiens_hsa034100.52595875
111Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.51737756
112Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.48936371
113Chemokine signaling pathway_Homo sapiens_hsa040620.48636638
114Type I diabetes mellitus_Homo sapiens_hsa049400.48255042
115Estrogen signaling pathway_Homo sapiens_hsa049150.46988734
116Inositol phosphate metabolism_Homo sapiens_hsa005620.46303335
117cAMP signaling pathway_Homo sapiens_hsa040240.45844908
118cGMP-PKG signaling pathway_Homo sapiens_hsa040220.44575298
119Salmonella infection_Homo sapiens_hsa051320.44256387
120MAPK signaling pathway_Homo sapiens_hsa040100.43548894
121Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.42887079
122Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.41587857
123Regulation of autophagy_Homo sapiens_hsa041400.41547112
124Phototransduction_Homo sapiens_hsa047440.41005165
125Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.40758878
126Phosphatidylinositol signaling system_Homo sapiens_hsa040700.40137997
127Vitamin B6 metabolism_Homo sapiens_hsa007500.40011605
128Pancreatic cancer_Homo sapiens_hsa052120.39641562
129Type II diabetes mellitus_Homo sapiens_hsa049300.39436035
130VEGF signaling pathway_Homo sapiens_hsa043700.39083014
131Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.38584950
132Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.36600775
133Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.35590000
134mTOR signaling pathway_Homo sapiens_hsa041500.35361010
135Galactose metabolism_Homo sapiens_hsa000520.35104340
136Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.34945743
137Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.34575596
138RNA polymerase_Homo sapiens_hsa030200.34271073
139Thyroid hormone synthesis_Homo sapiens_hsa049180.34005963
140Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.33890269
141Platelet activation_Homo sapiens_hsa046110.33875415
142Hepatitis B_Homo sapiens_hsa051610.33463665
143Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.32321531
144Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.31909911
145Hematopoietic cell lineage_Homo sapiens_hsa046400.31251004
146Fatty acid elongation_Homo sapiens_hsa000620.31072968
147Ether lipid metabolism_Homo sapiens_hsa005650.30526758
148ErbB signaling pathway_Homo sapiens_hsa040120.30101115
149Apoptosis_Homo sapiens_hsa042100.29691704
150Phospholipase D signaling pathway_Homo sapiens_hsa040720.28438538
151Pentose phosphate pathway_Homo sapiens_hsa000300.28243720
152Glycosaminoglycan degradation_Homo sapiens_hsa005310.27395818
153Tuberculosis_Homo sapiens_hsa051520.27321627
154NOD-like receptor signaling pathway_Homo sapiens_hsa046210.27244270
155Viral carcinogenesis_Homo sapiens_hsa052030.27114666
156Spliceosome_Homo sapiens_hsa030400.26123417
157African trypanosomiasis_Homo sapiens_hsa051430.26003236
158Sphingolipid signaling pathway_Homo sapiens_hsa040710.23239372
159AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.19254670

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »