GPR18

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)7.14282847
2antigen processing and presentation of endogenous antigen (GO:0019883)6.73962671
3negative T cell selection (GO:0043383)6.63932226
4negative thymic T cell selection (GO:0045060)6.58959762
5protein targeting to Golgi (GO:0000042)6.38898815
6positive thymic T cell selection (GO:0045059)6.36513661
7antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)6.28700947
8antigen processing and presentation of endogenous peptide antigen (GO:0002483)6.28700947
9establishment of protein localization to Golgi (GO:0072600)6.23414191
10regulation of B cell receptor signaling pathway (GO:0050855)6.16494462
11sperm motility (GO:0030317)6.08846647
12retrograde transport, vesicle recycling within Golgi (GO:0000301)5.94814089
13regulation of gamma-delta T cell differentiation (GO:0045586)5.89700644
14positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)5.80910855
15cellular response to interleukin-15 (GO:0071350)5.69263303
16thymic T cell selection (GO:0045061)5.63065121
17negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.52872969
18negative regulation of cell killing (GO:0031342)5.52872969
19regulation of gamma-delta T cell activation (GO:0046643)5.44650224
20positive T cell selection (GO:0043368)5.43735202
21response to interleukin-15 (GO:0070672)5.42718501
22B cell receptor signaling pathway (GO:0050853)5.37537060
23fusion of sperm to egg plasma membrane (GO:0007342)5.34752308
24regulation of isotype switching to IgG isotypes (GO:0048302)5.14273605
25T cell selection (GO:0045058)5.09208648
26interferon-gamma production (GO:0032609)5.08102195
27regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)4.90137649
28positive regulation of interleukin-2 biosynthetic process (GO:0045086)4.79665393
29T cell migration (GO:0072678)4.74435721
30leukocyte aggregation (GO:0070486)4.63593962
31antigen receptor-mediated signaling pathway (GO:0050851)4.52185705
32regulation of antigen receptor-mediated signaling pathway (GO:0050854)4.51122390
33acrosome reaction (GO:0007340)4.49907558
34regulation of interleukin-12 biosynthetic process (GO:0045075)4.46385551
35T cell costimulation (GO:0031295)4.40809305
36T cell receptor signaling pathway (GO:0050852)4.35205257
37lymphocyte costimulation (GO:0031294)4.32676728
38protein localization to Golgi apparatus (GO:0034067)4.28918658
39regulation of alpha-beta T cell proliferation (GO:0046640)4.25847773
40regulation of T cell tolerance induction (GO:0002664)4.25527510
41RNA destabilization (GO:0050779)4.25316795
42rRNA methylation (GO:0031167)4.24030108
43antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.22897386
44centriole replication (GO:0007099)4.15575632
45multicellular organism reproduction (GO:0032504)4.12688791
46microtubule depolymerization (GO:0007019)4.12340261
47regulation of B cell differentiation (GO:0045577)4.10145333
48regulation of T cell receptor signaling pathway (GO:0050856)4.07035441
49positive regulation of isotype switching (GO:0045830)4.00916755
50neutrophil activation involved in immune response (GO:0002283)3.94370756
51negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.84797426
52plasma membrane fusion (GO:0045026)3.84674053
53cellular response to zinc ion (GO:0071294)3.83024105
54positive regulation of alpha-beta T cell proliferation (GO:0046641)3.78979695
55leukocyte degranulation (GO:0043299)3.76933469
56regulation of response to interferon-gamma (GO:0060330)3.76408707
57mast cell activation (GO:0045576)3.71482612
58positive regulation of interleukin-2 production (GO:0032743)3.70778184
59regulation of interferon-gamma-mediated signaling pathway (GO:0060334)3.70056517
60interferon-gamma-mediated signaling pathway (GO:0060333)3.69922631
61response to type I interferon (GO:0034340)3.67656870
62positive regulation of immunoglobulin production (GO:0002639)3.66116797
63spermatid nucleus differentiation (GO:0007289)3.64232077
64positive regulation of B cell mediated immunity (GO:0002714)3.63111715
65positive regulation of immunoglobulin mediated immune response (GO:0002891)3.63111715
66type I interferon signaling pathway (GO:0060337)3.63052242
67cellular response to type I interferon (GO:0071357)3.63052242
68positive regulation of humoral immune response (GO:0002922)3.62942059
69seminiferous tubule development (GO:0072520)3.61362200
70NIK/NF-kappaB signaling (GO:0038061)3.58972799
71immune response-activating cell surface receptor signaling pathway (GO:0002429)3.58285531
72protein polyglutamylation (GO:0018095)3.56573478
73regulation of interleukin-2 biosynthetic process (GO:0045076)3.51424885
74B cell proliferation (GO:0042100)3.48464412
75sperm capacitation (GO:0048240)3.47980736
76positive regulation of DNA recombination (GO:0045911)3.47684588
77phosphatidylethanolamine biosynthetic process (GO:0006646)3.46761868
78myeloid cell activation involved in immune response (GO:0002275)3.45727274
79positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.45447393
80rRNA modification (GO:0000154)3.43333003
81regulation of type I interferon-mediated signaling pathway (GO:0060338)3.43193316
82microtubule polymerization or depolymerization (GO:0031109)3.41895991
83regulation of B cell mediated immunity (GO:0002712)3.41025524
84reproduction (GO:0000003)3.39638955
85activated T cell proliferation (GO:0050798)3.39399959
86centriole assembly (GO:0098534)3.39167911
87regulation of immunoglobulin mediated immune response (GO:0002889)3.39066513
88DNA packaging (GO:0006323)3.38702933
89defense response to protozoan (GO:0042832)3.37855804
90microtubule nucleation (GO:0007020)3.36303764
91positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)3.35986248
92positive regulation of natural killer cell mediated immunity (GO:0002717)3.35986248
93regulation of isotype switching (GO:0045191)3.35233183
94single strand break repair (GO:0000012)3.35037354
95positive regulation of granulocyte differentiation (GO:0030854)3.33460231
96regulation of natural killer cell mediated immunity (GO:0002715)3.33343273
97regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.33343273
98mature B cell differentiation (GO:0002335)3.33324868
99chromosome condensation (GO:0030261)3.31715131
100sperm-egg recognition (GO:0035036)3.30848534
101hepatocyte apoptotic process (GO:0097284)3.27850501
102spermatogenesis (GO:0007283)3.26952038
103tolerance induction (GO:0002507)3.26795784
104male gamete generation (GO:0048232)3.25820647
105sequestering of actin monomers (GO:0042989)3.25578534
106histone mRNA catabolic process (GO:0071044)3.24945180
107regulation of immunoglobulin production (GO:0002637)3.24660682
108phosphatidylethanolamine metabolic process (GO:0046337)3.23591564
109macrophage activation involved in immune response (GO:0002281)3.23004917
110Arp2/3 complex-mediated actin nucleation (GO:0034314)3.22374810
111response to pheromone (GO:0019236)3.22366040
112spermatid development (GO:0007286)3.21552544
113positive regulation of B cell differentiation (GO:0045579)3.20198463
114positive regulation by symbiont of host defense response (GO:0052509)3.19606594
115modulation by symbiont of host defense response (GO:0052031)3.19606594
116modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.19606594
117modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.19606594
118positive regulation by organism of defense response of other organism involved in symbiotic interact3.19606594
119modulation by symbiont of host immune response (GO:0052553)3.19606594
120negative regulation of B cell proliferation (GO:0030889)3.19059695
121neutrophil activation (GO:0042119)3.17825473
122negative regulation of T cell receptor signaling pathway (GO:0050860)3.16654116
123immunoglobulin mediated immune response (GO:0016064)3.16489496
124regulation of interferon-beta biosynthetic process (GO:0045357)3.15958289
125positive regulation of tolerance induction (GO:0002645)3.15360885
126regulation of tolerance induction (GO:0002643)3.12029791
127positive regulation of T cell mediated cytotoxicity (GO:0001916)3.11306613
128regulation of T cell mediated cytotoxicity (GO:0001914)3.11276717
129response to protozoan (GO:0001562)3.10244551
130microglial cell activation (GO:0001774)3.09621195
131regulation of B cell proliferation (GO:0030888)3.09206498
132negative regulation of lymphocyte mediated immunity (GO:0002707)3.09142157
133regulation of regulatory T cell differentiation (GO:0045589)3.07050136
134natural killer cell activation (GO:0030101)3.06677151
135production of molecular mediator involved in inflammatory response (GO:0002532)3.05709104
136leukocyte cell-cell adhesion (GO:0007159)3.05530830
137myeloid dendritic cell activation (GO:0001773)3.03839001
138cell-cell recognition (GO:0009988)3.02791986
139lymphocyte homeostasis (GO:0002260)3.01614512
140gamete generation (GO:0007276)3.00423447
141cellular extravasation (GO:0045123)2.98373478
142negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.97438346
143T cell homeostasis (GO:0043029)2.97415299
144positive regulation of B cell activation (GO:0050871)2.97133574
145positive regulation of B cell proliferation (GO:0030890)2.96891522
146single fertilization (GO:0007338)2.96172558
147cytidine deamination (GO:0009972)2.93627515
148cytidine metabolic process (GO:0046087)2.93627515
149cytidine catabolic process (GO:0006216)2.93627515
150JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.92668963
151lymph node development (GO:0048535)2.92630485
152regulation of leukocyte mediated cytotoxicity (GO:0001910)2.92395851
153negative regulation of T cell mediated immunity (GO:0002710)2.90181628
154positive regulation of cell killing (GO:0031343)2.89142361
155positive regulation of interferon-gamma production (GO:0032729)2.88891722
156regulation of B cell activation (GO:0050864)2.87526842
157negative regulation of T-helper cell differentiation (GO:0045623)2.85939085
158negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.85939085
159germinal center formation (GO:0002467)2.84773316
160mast cell degranulation (GO:0043303)2.84231300
161mast cell activation involved in immune response (GO:0002279)2.84231300
162positive regulation of leukocyte mediated cytotoxicity (GO:0001912)2.84224931
163positive regulation of mast cell activation (GO:0033005)2.81196793
164negative regulation of alpha-beta T cell activation (GO:0046636)2.78631426
165cell wall macromolecule catabolic process (GO:0016998)2.78505236

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse6.95156484
2* IRF8_22096565_ChIP-ChIP_GC-B_Human5.33099350
3STAT6_20620947_ChIP-Seq_CD4_POS_T_Human5.24324283
4* IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.59200760
5E2F7_22180533_ChIP-Seq_HELA_Human3.75649568
6MYC_22102868_ChIP-Seq_BL_Human3.60537469
7* IRF8_21731497_ChIP-ChIP_J774_Mouse3.57935522
8* SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.48739778
9IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.41677160
10* STAT4_19710469_ChIP-ChIP_TH1__Mouse3.25552778
11STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.22738976
12RUNX_20019798_ChIP-Seq_JUKART_Human3.10723451
13* MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.09389350
14* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse3.09020806
15MYB_26560356_Chip-Seq_TH2_Human2.98216477
16MAF_26560356_Chip-Seq_TH1_Human2.75188968
17MYB_26560356_Chip-Seq_TH1_Human2.61807099
18FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.48441986
19* IRF8_27001747_Chip-Seq_BMDM_Mouse2.43729033
20UTX_26944678_Chip-Seq_JUKART_Human2.41795448
21SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.40612242
22EGR1_19374776_ChIP-ChIP_THP-1_Human2.34650915
23NOTCH1_21737748_ChIP-Seq_TLL_Human2.34540584
24VDR_21846776_ChIP-Seq_THP-1_Human2.33163643
25E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.16427526
26RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.16054735
27SPI1_23547873_ChIP-Seq_NB4_Human2.12736262
28* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.11476124
29* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.07264212
30FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.96945162
31MAF_26560356_Chip-Seq_TH2_Human1.90759629
32RUNX1_22412390_ChIP-Seq_EML_Mouse1.89470697
33ELF1_17652178_ChIP-ChIP_JURKAT_Human1.86657610
34ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.84675530
35NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.82644862
36GATA3_27048872_Chip-Seq_THYMUS_Human1.79859947
37MYB_21317192_ChIP-Seq_ERMYB_Mouse1.76301060
38* VDR_24763502_ChIP-Seq_THP-1_Human1.69730725
39POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.63787216
40TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.63787216
41KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.63693924
42BP1_19119308_ChIP-ChIP_Hs578T_Human1.59317752
43ER_23166858_ChIP-Seq_MCF-7_Human1.59079671
44SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.58231182
45TCF7_22412390_ChIP-Seq_EML_Mouse1.57693906
46SCL_19346495_ChIP-Seq_HPC-7_Human1.54958171
47MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.54920161
48TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.54652319
49IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.53993320
50CBP_20019798_ChIP-Seq_JUKART_Human1.53993320
51BRD4_27068464_Chip-Seq_AML-cells_Mouse1.53844294
52SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.53595577
53NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.51508485
54EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.49619398
55RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.48750962
56VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.48521771
57CIITA_25753668_ChIP-Seq_RAJI_Human1.47545223
58* VDR_24787735_ChIP-Seq_THP-1_Human1.45849105
59GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.41891651
60VDR_23849224_ChIP-Seq_CD4+_Human1.40813523
61SPI1_23127762_ChIP-Seq_K562_Human1.40043509
62VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.39710490
63FLI1_27457419_Chip-Seq_LIVER_Mouse1.39586073
64SMRT_27268052_Chip-Seq_Bcells_Human1.36047936
65GATA2_22383799_ChIP-Seq_G1ME_Mouse1.34750591
66GATA3_26560356_Chip-Seq_TH1_Human1.33636951
67FOXP3_21729870_ChIP-Seq_TREG_Human1.33357858
68GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.30201761
69PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.26982301
70SALL4_22934838_ChIP-ChIP_CD34+_Human1.26914901
71KDM2B_26808549_Chip-Seq_DND41_Human1.24592814
72FUS_26573619_Chip-Seq_HEK293_Human1.23482364
73PU.1_20513432_ChIP-Seq_Bcells_Mouse1.22769086
74KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.22611665
75ERG_20887958_ChIP-Seq_HPC-7_Mouse1.21947952
76CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.20921369
77PRDM14_20953172_ChIP-Seq_ESCs_Human1.20376113
78MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.20238011
79HOXB4_20404135_ChIP-ChIP_EML_Mouse1.19644666
80GATA3_26560356_Chip-Seq_TH2_Human1.19597184
81E2F4_17652178_ChIP-ChIP_JURKAT_Human1.19513131
82TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human1.19376913
83PU_27001747_Chip-Seq_BMDM_Mouse1.18576803
84EZH2_22144423_ChIP-Seq_EOC_Human1.17468435
85UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.16167263
86FOXM1_23109430_ChIP-Seq_U2OS_Human1.16078461
87GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.15846912
88EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.15812513
89RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.14457345
90CTBP1_25329375_ChIP-Seq_LNCAP_Human1.14435390
91TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.11791709
92ERG_20517297_ChIP-Seq_VCAP_Human1.11320768
93* CEBPB_22108803_ChIP-Seq_LS180_Human1.10404652
94KDM2B_26808549_Chip-Seq_SUP-B15_Human1.09603330
95TAF15_26573619_Chip-Seq_HEK293_Human1.09199037
96Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.09174894
97NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.08822455
98CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.08341707
99PCGF2_27294783_Chip-Seq_NPCs_Mouse1.08103976
100LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.07697457
101PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.06376923
102FOXA1_21572438_ChIP-Seq_LNCaP_Human1.05962785
103CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.05303610
104SUZ12_27294783_Chip-Seq_NPCs_Mouse1.04499980
105RBPJ_21746931_ChIP-Seq_IB4_Human1.04347102
106GABP_17652178_ChIP-ChIP_JURKAT_Human1.03518014
107NFE2_27457419_Chip-Seq_LIVER_Mouse1.02858037
108PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.00733555
109SMAD_19615063_ChIP-ChIP_OVARY_Human1.00467727
110PCGF2_27294783_Chip-Seq_ESCs_Mouse1.00464284
111GATA1_22383799_ChIP-Seq_G1ME_Mouse0.99967733
112GATA1_19941826_ChIP-Seq_K562_Human0.99073348
113CBX2_22325352_ChIP-Seq_293T-Rex_Human0.98108161
114NANOG_20526341_ChIP-Seq_ESCs_Human0.98087791
115EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.97576836
116ETV1_20927104_ChIP-Seq_GIST48_Human0.97314610
117FOXA1_25329375_ChIP-Seq_VCAP_Human0.97167489
118FOXA1_27270436_Chip-Seq_PROSTATE_Human0.97167489
119KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.97060571
120ELK3_25401928_ChIP-Seq_HUVEC_Human0.96240799
121CTBP2_25329375_ChIP-Seq_LNCAP_Human0.96090996
122HNFA_21074721_ChIP-Seq_CACO-2_Human0.94796801
123TAF2_19829295_ChIP-Seq_ESCs_Human0.94709742
124CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.94596225
125GATA3_21878914_ChIP-Seq_MCF-7_Human0.93873561
126STAT3_23295773_ChIP-Seq_U87_Human0.92691452
127PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.92558143
128RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.92404963
129SPI1_20517297_ChIP-Seq_HL60_Human0.91939228
130TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.91863043
131AR_25329375_ChIP-Seq_VCAP_Human0.91599810
132ELK1_19687146_ChIP-ChIP_HELA_Human0.91502260
133LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.91264178
134SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.91233017
135EST1_17652178_ChIP-ChIP_JURKAT_Human0.90524049
136* POU3F2_20337985_ChIP-ChIP_501MEL_Human0.90195595
137TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.90105784
138BCL6_27268052_Chip-Seq_Bcells_Human0.90059689
139P300_19829295_ChIP-Seq_ESCs_Human0.89428135
140GATA6_21074721_ChIP-Seq_CACO-2_Human0.89415238
141SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.89024947
142NFYB_21822215_ChIP-Seq_K562_Human0.88350585
143* OCT4_20526341_ChIP-Seq_ESCs_Human0.88306105
144TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.88277771
145EZH2_27294783_Chip-Seq_NPCs_Mouse0.87789373
146FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.84461551
147FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.83920834
148GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.80893150
149RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.76177797
150NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.75556974
151BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.74780867
152PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.74303505
153KDM5A_27292631_Chip-Seq_BREAST_Human0.73449032
154FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.73407605
155XRN2_22483619_ChIP-Seq_HELA_Human0.72108857
156SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.70789751
157CTCF_26484167_Chip-Seq_Bcells_Mouse0.68542427
158GATA1_19941827_ChIP-Seq_MEL_Mouse0.67853958
159P300_27268052_Chip-Seq_Bcells_Human0.66240147
160KDM2B_26808549_Chip-Seq_JURKAT_Human0.66223524
161NCOR1_26117541_ChIP-Seq_K562_Human0.66068411

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.90029129
2MP0003763_abnormal_thymus_physiology4.63058373
3MP0005671_abnormal_response_to4.54953593
4MP0005410_abnormal_fertilization4.45205996
5MP0001800_abnormal_humoral_immune4.04060194
6MP0000685_abnormal_immune_system3.82201849
7MP0005387_immune_system_phenotype3.76907097
8MP0001790_abnormal_immune_system3.76907097
9MP0003878_abnormal_ear_physiology3.49706856
10MP0005377_hearing/vestibular/ear_phenot3.49706856
11MP0005000_abnormal_immune_tolerance3.28942754
12MP0002452_abnormal_antigen_presenting3.21990390
13MP0002723_abnormal_immune_serum3.15957260
14MP0002420_abnormal_adaptive_immunity3.13314255
15MP0001819_abnormal_immune_cell3.07182774
16MP0009785_altered_susceptibility_to3.01073493
17MP0002398_abnormal_bone_marrow2.94944823
18MP0002166_altered_tumor_susceptibility2.87726936
19MP0005025_abnormal_response_to2.66208440
20MP0000716_abnormal_immune_system2.63828279
21MP0003436_decreased_susceptibility_to2.50710942
22MP0009333_abnormal_splenocyte_physiolog2.50661208
23MP0000689_abnormal_spleen_morphology2.44226504
24MP0002405_respiratory_system_inflammati2.43791743
25MP0002148_abnormal_hypersensitivity_rea2.36723949
26MP0002722_abnormal_immune_system2.33106157
27MP0001873_stomach_inflammation2.30405434
28MP0002006_tumorigenesis2.30367842
29MP0003303_peritoneal_inflammation2.23118029
30MP0000703_abnormal_thymus_morphology2.22813341
31MP0002429_abnormal_blood_cell2.16408042
32MP0002419_abnormal_innate_immunity2.15597436
33MP0006082_CNS_inflammation2.13113082
34MP0004510_myositis2.08284457
35MP0010155_abnormal_intestine_physiology2.02496989
36MP0005451_abnormal_body_composition1.99526287
37MP0008877_abnormal_DNA_methylation1.95190847
38MP0004947_skin_inflammation1.91171345
39MP0002396_abnormal_hematopoietic_system1.91070378
40MP0002933_joint_inflammation1.86357065
41MP0001845_abnormal_inflammatory_respons1.81882202
42MP0003866_abnormal_defecation1.75379377
43MP0003300_gastrointestinal_ulcer1.74781465
44MP0001853_heart_inflammation1.70054520
45MP0003724_increased_susceptibility_to1.69117633
46MP0003698_abnormal_male_reproductive1.68229984
47MP0000569_abnormal_digit_pigmentation1.67671770
48MP0001929_abnormal_gametogenesis1.65103166
49MP0005464_abnormal_platelet_physiology1.56798968
50MP0005310_abnormal_salivary_gland1.53796713
51MP0003787_abnormal_imprinting1.45070303
52MP0004808_abnormal_hematopoietic_stem1.35217933
53MP0000858_altered_metastatic_potential1.29033887
54MP0008469_abnormal_protein_level1.20405651
55MP0008057_abnormal_DNA_replication1.19709773
56MP0002019_abnormal_tumor_incidence1.15999050
57MP0005670_abnormal_white_adipose1.12460086
58MP0003448_altered_tumor_morphology1.11695348
59MP0003646_muscle_fatigue1.08269226
60MP0001485_abnormal_pinna_reflex1.05727495
61MP0001533_abnormal_skeleton_physiology1.03555481
62MP0000465_gastrointestinal_hemorrhage1.01893583
63MP0003879_abnormal_hair_cell0.99975389
64MP0005379_endocrine/exocrine_gland_phen0.96379423
65MP0000490_abnormal_crypts_of0.96143928
66MP0004381_abnormal_hair_follicle0.94751672
67MP0010094_abnormal_chromosome_stability0.94390933
68MP0004742_abnormal_vestibular_system0.93775243
69MP0005075_abnormal_melanosome_morpholog0.91035568
70MP0003077_abnormal_cell_cycle0.89948463
71MP0008995_early_reproductive_senescence0.89847968
72MP0003693_abnormal_embryo_hatching0.89790497
73MP0002009_preneoplasia0.85948033
74MP0010352_gastrointestinal_tract_polyps0.85291432
75MP0009115_abnormal_fat_cell0.82922839
76MP0009764_decreased_sensitivity_to0.81699789
77MP0003828_pulmonary_edema0.81013611
78MP0002138_abnormal_hepatobiliary_system0.80973996
79MP0002928_abnormal_bile_duct0.80935448
80MP0008872_abnormal_physiological_respon0.80123964
81MP0008004_abnormal_stomach_pH0.79929663
82MP0004883_abnormal_blood_vessel0.78926745
83MP0001765_abnormal_ion_homeostasis0.78762704
84MP0001545_abnormal_hematopoietic_system0.78705886
85MP0005397_hematopoietic_system_phenotyp0.78705886
86MP0003045_fibrosis0.78316084
87MP0002210_abnormal_sex_determination0.78072953
88MP0001986_abnormal_taste_sensitivity0.75701853
89MP0005084_abnormal_gallbladder_morpholo0.73837207
90MP0005174_abnormal_tail_pigmentation0.72679044
91MP0002132_abnormal_respiratory_system0.72225880
92MP0001851_eye_inflammation0.70889063
93MP0002998_abnormal_bone_remodeling0.70782882
94MP0002161_abnormal_fertility/fecundity0.70147187
95MP0010307_abnormal_tumor_latency0.68823811
96MP0002136_abnormal_kidney_physiology0.67832055
97MP0009763_increased_sensitivity_to0.67784944
98MP0008058_abnormal_DNA_repair0.65586578
99MP0006054_spinal_hemorrhage0.62311177
100MP0004957_abnormal_blastocyst_morpholog0.61296146
101MP0005167_abnormal_blood-brain_barrier0.60624502
102MP0001486_abnormal_startle_reflex0.60609656
103MP0005023_abnormal_wound_healing0.60398679
104MP0001145_abnormal_male_reproductive0.59509276
105MP0003011_delayed_dark_adaptation0.58923913
106MP0000230_abnormal_systemic_arterial0.57785258
107MP0000653_abnormal_sex_gland0.57192287
108MP0001663_abnormal_digestive_system0.54562788
109MP0005645_abnormal_hypothalamus_physiol0.54526858
110MP0009765_abnormal_xenobiotic_induced0.53999206
111MP0000313_abnormal_cell_death0.51778696
112MP0010234_abnormal_vibrissa_follicle0.51711820
113MP0000015_abnormal_ear_pigmentation0.51441075
114MP0002693_abnormal_pancreas_physiology0.51097473
115MP0003111_abnormal_nucleus_morphology0.50572435
116MP0000609_abnormal_liver_physiology0.50473864
117MP0005166_decreased_susceptibility_to0.50411045
118MP0005076_abnormal_cell_differentiation0.49266560
119MP0001191_abnormal_skin_condition0.48167597
120MP0002095_abnormal_skin_pigmentation0.48166325
121MP0002163_abnormal_gland_morphology0.47220742
122MP0001348_abnormal_lacrimal_gland0.46362067
123MP0009278_abnormal_bone_marrow0.46058274
124MP0000249_abnormal_blood_vessel0.45541392
125MP0008961_abnormal_basal_metabolism0.44571416
126MP0003172_abnormal_lysosome_physiology0.44430386
127MP0000477_abnormal_intestine_morphology0.44032160
128MP0003183_abnormal_peptide_metabolism0.43856864
129MP0003795_abnormal_bone_structure0.43315773
130MP0003453_abnormal_keratinocyte_physiol0.42621558
131MP0002083_premature_death0.40943226
132MP0005058_abnormal_lysosome_morphology0.38704003
133MP0008007_abnormal_cellular_replicative0.36982344
134MP0000350_abnormal_cell_proliferation0.36049222

Predicted human phenotypes

RankGene SetZ-score
1Recurrent bronchitis (HP:0002837)6.33517031
2Agammaglobulinemia (HP:0004432)6.20311314
3T lymphocytopenia (HP:0005403)6.02912286
4Abnormality of T cell number (HP:0011839)5.97601621
5IgM deficiency (HP:0002850)4.80972757
6Recurrent viral infections (HP:0004429)4.78546918
7Elevated erythrocyte sedimentation rate (HP:0003565)4.76713299
8Abnormality of T cells (HP:0002843)4.70291111
9Recurrent sinusitis (HP:0011108)4.65304865
10IgG deficiency (HP:0004315)4.59865102
11Severe combined immunodeficiency (HP:0004430)4.57563778
12Combined immunodeficiency (HP:0005387)4.51962575
13Chronic otitis media (HP:0000389)4.43100010
14Gastrointestinal stroma tumor (HP:0100723)4.42433351
15Lymphopenia (HP:0001888)4.37575253
16Recurrent fungal infections (HP:0002841)4.37553507
17Abnormality of cells of the lymphoid lineage (HP:0012140)4.25783172
18Recurrent cutaneous fungal infections (HP:0011370)4.22166923
19Chronic mucocutaneous candidiasis (HP:0002728)4.22166923
20Panhypogammaglobulinemia (HP:0003139)4.22027724
21Meningitis (HP:0001287)4.12446424
22Recurrent abscess formation (HP:0002722)4.10656307
23Eczematoid dermatitis (HP:0000976)4.08742103
24Thyroiditis (HP:0100646)4.07834951
25Chronic hepatic failure (HP:0100626)4.06222761
26Stomatitis (HP:0010280)4.05499460
27Abnormal delayed hypersensitivity skin test (HP:0002963)3.99870290
28Parkinsonism with favorable response to dopaminergic medication (HP:0002548)3.98439243
29Myositis (HP:0100614)3.77214941
30Chronic diarrhea (HP:0002028)3.76837553
31Vasculitis (HP:0002633)3.76583160
32Cellulitis (HP:0100658)3.75290240
33B lymphocytopenia (HP:0010976)3.72190948
34Abnormality of B cell number (HP:0010975)3.72190948
35IgA deficiency (HP:0002720)3.70437233
36Inflammation of the large intestine (HP:0002037)3.68334184
37Verrucae (HP:0200043)3.67849542
38Papilloma (HP:0012740)3.67849542
39Nasal polyposis (HP:0100582)3.63061692
40Autoimmune thrombocytopenia (HP:0001973)3.62980925
41Increased IgM level (HP:0003496)3.62707309
42Bronchitis (HP:0012387)3.62437219
43Chronic sinusitis (HP:0011109)3.61480805
44Gastrointestinal inflammation (HP:0004386)3.58752906
45Abnormality of T cell physiology (HP:0011840)3.45728776
46Colitis (HP:0002583)3.43929029
47Recurrent bacterial skin infections (HP:0005406)3.41933872
48Mediastinal lymphadenopathy (HP:0100721)3.39614726
49Abnormality of eosinophils (HP:0001879)3.37179311
50Pustule (HP:0200039)3.30735114
51Recurrent skin infections (HP:0001581)3.28750183
52Prolonged bleeding time (HP:0003010)3.17999392
53Autoimmune hemolytic anemia (HP:0001890)3.16325032
54Emphysema (HP:0002097)3.16296884
55Recurrent otitis media (HP:0000403)3.11446874
56Eosinophilia (HP:0001880)3.08703350
57Lymphoma (HP:0002665)3.05010450
58Severe visual impairment (HP:0001141)3.04297143
59Leukocytosis (HP:0001974)3.00275126
60Abnormality of the nasal mucosa (HP:0000433)3.00068935
61Tubulointerstitial nephritis (HP:0001970)2.98213853
62Abnormality of the fingertips (HP:0001211)2.96949226
63Pulmonary infiltrates (HP:0002113)2.96019240
64Encephalitis (HP:0002383)2.92317702
65Recurrent pneumonia (HP:0006532)2.87901607
66Recurrent lower respiratory tract infections (HP:0002783)2.82664886
67Chronic obstructive pulmonary disease (HP:0006510)2.79004793
68Obstructive lung disease (HP:0006536)2.79004793
69Gingival bleeding (HP:0000225)2.77463120
70Optic neuritis (HP:0100653)2.73366309
71Retrobulbar optic neuritis (HP:0100654)2.73366309
72Attenuation of retinal blood vessels (HP:0007843)2.72757468
73Dynein arm defect of respiratory motile cilia (HP:0012255)2.72543537
74Absent/shortened dynein arms (HP:0200106)2.72543537
75Thrombocytosis (HP:0001894)2.67414101
76Granulocytopenia (HP:0001913)2.65673601
77Visual hallucinations (HP:0002367)2.65381375
78Hypergammaglobulinemia (HP:0010702)2.61378830
79Restrictive lung disease (HP:0002091)2.57323130
80Osteomyelitis (HP:0002754)2.57201842
81Menstrual irregularities (HP:0000858)2.56836882
82Joint swelling (HP:0001386)2.55119801
83Hypoplasia of the thymus (HP:0000778)2.52790373
84Asymmetric septal hypertrophy (HP:0001670)2.50241919
85Orchitis (HP:0100796)2.49083725
86Sepsis (HP:0100806)2.46561351
87Spontaneous hematomas (HP:0007420)2.43219643
88Hemoptysis (HP:0002105)2.41611819
89Facial shape deformation (HP:0011334)2.39913212
90Potter facies (HP:0002009)2.39913212
91Neoplasm of the tracheobronchial system (HP:0100552)2.38063365
92Abnormality of dental color (HP:0011073)2.32645693
93Cone-rod dystrophy (HP:0000548)2.29848289
94Gastrointestinal infarctions (HP:0005244)2.29508658
95Skin rash (HP:0000988)2.28746588
96Increased IgE level (HP:0003212)2.27289603
97Alveolar cell carcinoma (HP:0006519)2.26523454
98Hypoproteinemia (HP:0003075)2.25102775
99Skin ulcer (HP:0200042)2.22591836
100Acute hepatic failure (HP:0006554)2.22499725
101Gingivitis (HP:0000230)2.18147141
102Recurrent gram-negative bacterial infections (HP:0005420)2.17400449
103Keratoconjunctivitis sicca (HP:0001097)2.14906951
104Leukopenia (HP:0001882)2.10057047
105Truncal obesity (HP:0001956)2.09337383
106Abnormality of the prostate (HP:0008775)2.07172885
107Arterial thrombosis (HP:0004420)2.04552534
108Abnormality of macrophages (HP:0004311)2.03700633
109Pulmonary embolism (HP:0002204)2.03086624
110Basal cell carcinoma (HP:0002671)2.02805127
111Neutropenia (HP:0001875)2.02077341
112Hyperkalemia (HP:0002153)2.01513848
113Interstitial pulmonary disease (HP:0006530)2.01432037
114Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.99475372
115Postural instability (HP:0002172)1.98478146
116Arthralgia (HP:0002829)1.98401545
117Portal hypertension (HP:0001409)1.96607584
118Keratoconjunctivitis (HP:0001096)1.94143225
119Petechiae (HP:0000967)1.91411166
120Chest pain (HP:0100749)1.87771051
121Bronchiectasis (HP:0002110)1.85730865
122Aplasia/Hypoplasia of the thymus (HP:0010515)1.79374274
123Cheilitis (HP:0100825)1.79364367
124Periodontitis (HP:0000704)1.78316850
125Hepatitis (HP:0012115)1.77832190
126Epistaxis (HP:0000421)1.75988632

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K16.71013497
2TXK4.86750553
3PLK44.85952912
4BMPR22.89364641
5PIK3CG2.88568189
6ZAP702.88289378
7ITK2.87612248
8BLK2.58817884
9JAK32.58726855
10MAP3K142.58152020
11IKBKE2.49069244
12GRK62.46851017
13TYK22.43750787
14INSRR2.32459896
15SYK2.28231301
16STK102.26506054
17BTK2.11886971
18JAK12.10558338
19TBK12.08983474
20FGFR41.98133819
21TEC1.96707190
22MST41.85678426
23PLK21.84881624
24NLK1.82441646
25LCK1.82109851
26CSK1.74377859
27ERN11.73844780
28PNCK1.69469071
29KIT1.68165794
30CSF1R1.67435028
31TESK21.64406048
32IRAK41.60799703
33MAP3K101.58623641
34MAP3K131.58606143
35IKBKB1.51843084
36HCK1.49676798
37LYN1.41400189
38CLK11.38899081
39FGFR31.37641662
40KDR1.35883221
41NME21.35764195
42LRRK21.25715173
43FGR1.23541542
44PRKCH1.22627836
45PRKCQ1.15632464
46MAP3K111.13414292
47NEK61.10005273
48PTK2B1.07075137
49RPS6KA41.04713607
50PIM11.04301655
51TYRO31.04280038
52RIPK41.02846064
53MARK30.98327956
54CHUK0.94664381
55FES0.91332039
56SIK30.90192004
57SIK20.85669213
58FRK0.85469089
59SGK20.83102260
60CAMK1G0.83025831
61TGFBR20.82744662
62EEF2K0.81995341
63PDPK10.79334429
64CAMKK20.77067106
65MAP4K20.74663539
66EIF2AK10.71239338
67EIF2AK30.67334538
68IRAK30.64004351
69MATK0.62301153
70TNK20.62188571
71CDK120.60502656
72MAP3K120.58704464
73CDK190.57679466
74WNK10.57428979
75JAK20.53127645
76TLK10.52882777
77EPHA30.52424894
78ADRBK20.52331604
79INSR0.51924718
80EPHB10.50387004
81FYN0.50342796
82MELK0.49358204
83MAP3K30.48609718
84TAOK30.48382131
85BRSK20.47896448
86CDK40.47426959
87MAP2K20.46724326
88DYRK1B0.46483738
89MAP3K10.45370091
90STK40.45149124
91SGK2230.43148821
92SGK4940.43148821
93ALK0.42203542
94FLT30.41978409
95PRKCD0.39791100
96SGK10.39022063
97TESK10.38301635
98MARK20.38188590
99MAP3K70.37965481
100MAP2K30.37341429
101PDK10.37220284
102GRK50.36891434
103CDC70.35477584
104STK380.34633739
105PRKD20.34570736
106PKN20.34105632
107ABL10.33279705
108SGK30.32611190
109PIM20.32411962
110GRK10.32408187
111CDK30.32040279
112HIPK20.31781069
113MAPK150.31426820
114IGF1R0.30577307
115CAMK10.30576490
116BRD40.28733741
117RPS6KA50.28289702
118MAPK110.28047316
119ACVR1B0.27544836
120NEK20.27503586
121MAPK70.26022482
122MAPKAPK20.25712500
123CDK90.25502831
124PASK0.25378909
125AKT30.24956037
126ATR0.24340704
127RAF10.23278913
128PRKG10.23113141
129NUAK10.22705374
130KSR20.22177696
131NEK90.21779624
132SIK10.21323354
133TRIB30.20779885
134TSSK60.20679993
135PAK30.20626924
136STK240.20474779
137IRAK10.20403439
138RPS6KA60.20355287
139PDGFRB0.19986335
140MAPK120.19359559
141MAPK30.19125860
142EGFR0.17771609

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053406.06722844
2Graft-versus-host disease_Homo sapiens_hsa053323.38626842
3Intestinal immune network for IgA production_Homo sapiens_hsa046723.21795766
4Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.97920955
5T cell receptor signaling pathway_Homo sapiens_hsa046602.96615230
6B cell receptor signaling pathway_Homo sapiens_hsa046622.95113388
7Antigen processing and presentation_Homo sapiens_hsa046122.89972508
8Allograft rejection_Homo sapiens_hsa053302.84794477
9NF-kappa B signaling pathway_Homo sapiens_hsa040642.82966022
10Measles_Homo sapiens_hsa051622.52365535
11Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.52081047
12Hematopoietic cell lineage_Homo sapiens_hsa046402.42274729
13Leishmaniasis_Homo sapiens_hsa051402.11434082
14Fatty acid biosynthesis_Homo sapiens_hsa000611.96076409
15Osteoclast differentiation_Homo sapiens_hsa043801.95771728
16Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.82085555
17Viral myocarditis_Homo sapiens_hsa054161.75078708
18Herpes simplex infection_Homo sapiens_hsa051681.72349734
19Autoimmune thyroid disease_Homo sapiens_hsa053201.71756446
20Olfactory transduction_Homo sapiens_hsa047401.68009304
21RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.64077123
22Type I diabetes mellitus_Homo sapiens_hsa049401.61088242
23Jak-STAT signaling pathway_Homo sapiens_hsa046301.56262048
24Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.47078461
25Base excision repair_Homo sapiens_hsa034101.33325643
26Toll-like receptor signaling pathway_Homo sapiens_hsa046201.29808683
27DNA replication_Homo sapiens_hsa030301.27820069
28Chemokine signaling pathway_Homo sapiens_hsa040621.27615662
29NOD-like receptor signaling pathway_Homo sapiens_hsa046211.27047395
30Ribosome_Homo sapiens_hsa030101.26309765
31Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.26123272
32Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.22593446
33Influenza A_Homo sapiens_hsa051641.21297469
34Toxoplasmosis_Homo sapiens_hsa051451.21265832
35Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.19786927
36Leukocyte transendothelial migration_Homo sapiens_hsa046701.18357888
37Mismatch repair_Homo sapiens_hsa034301.15675877
38Shigellosis_Homo sapiens_hsa051311.15011744
39Hepatitis B_Homo sapiens_hsa051611.13890822
40Non-homologous end-joining_Homo sapiens_hsa034501.12132179
41Apoptosis_Homo sapiens_hsa042101.08485319
42Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.07954465
43Tuberculosis_Homo sapiens_hsa051521.03467541
44Epstein-Barr virus infection_Homo sapiens_hsa051691.02540403
45Asthma_Homo sapiens_hsa053101.02020226
46Acute myeloid leukemia_Homo sapiens_hsa052210.99521542
47Legionellosis_Homo sapiens_hsa051340.99078424
48Malaria_Homo sapiens_hsa051440.98490582
49TNF signaling pathway_Homo sapiens_hsa046680.97819755
50Phototransduction_Homo sapiens_hsa047440.96171754
51Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.95917876
52HTLV-I infection_Homo sapiens_hsa051660.92821770
53SNARE interactions in vesicular transport_Homo sapiens_hsa041300.89137575
54Dorso-ventral axis formation_Homo sapiens_hsa043200.88179605
55Glycerophospholipid metabolism_Homo sapiens_hsa005640.81876442
56Pancreatic cancer_Homo sapiens_hsa052120.78351749
57Staphylococcus aureus infection_Homo sapiens_hsa051500.75512507
58Spliceosome_Homo sapiens_hsa030400.75004464
59Viral carcinogenesis_Homo sapiens_hsa052030.74411570
60Pertussis_Homo sapiens_hsa051330.74177907
61Hepatitis C_Homo sapiens_hsa051600.74147261
62Salmonella infection_Homo sapiens_hsa051320.73235240
63Proteasome_Homo sapiens_hsa030500.72028654
64Nitrogen metabolism_Homo sapiens_hsa009100.70768990
65Regulation of autophagy_Homo sapiens_hsa041400.68879288
66p53 signaling pathway_Homo sapiens_hsa041150.68647320
67Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.68418071
68Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.68007355
69Platelet activation_Homo sapiens_hsa046110.67210040
70Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.65870017
71Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.65073160
72Homologous recombination_Homo sapiens_hsa034400.64449468
73Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.64429259
74African trypanosomiasis_Homo sapiens_hsa051430.62435645
75Nucleotide excision repair_Homo sapiens_hsa034200.62008717
76Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.61931914
77Transcriptional misregulation in cancer_Homo sapiens_hsa052020.61160746
78Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.61051371
79Chronic myeloid leukemia_Homo sapiens_hsa052200.59344493
80Colorectal cancer_Homo sapiens_hsa052100.58864421
81Type II diabetes mellitus_Homo sapiens_hsa049300.58496761
82Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.56860291
83VEGF signaling pathway_Homo sapiens_hsa043700.54895774
84AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.54348548
85Neurotrophin signaling pathway_Homo sapiens_hsa047220.51440261
86Serotonergic synapse_Homo sapiens_hsa047260.50075648
87RNA degradation_Homo sapiens_hsa030180.47909568
88Morphine addiction_Homo sapiens_hsa050320.46811909
89Carbohydrate digestion and absorption_Homo sapiens_hsa049730.46807199
90ABC transporters_Homo sapiens_hsa020100.46783654
91Prolactin signaling pathway_Homo sapiens_hsa049170.46247599
92Rheumatoid arthritis_Homo sapiens_hsa053230.44414923
93Non-small cell lung cancer_Homo sapiens_hsa052230.42031703
94Small cell lung cancer_Homo sapiens_hsa052220.41083431
95Other glycan degradation_Homo sapiens_hsa005110.39458439
96Taste transduction_Homo sapiens_hsa047420.38524483
97Phagosome_Homo sapiens_hsa041450.36028586
98Endocytosis_Homo sapiens_hsa041440.34555487
99Fanconi anemia pathway_Homo sapiens_hsa034600.33493262
100RNA polymerase_Homo sapiens_hsa030200.33168417
101Choline metabolism in cancer_Homo sapiens_hsa052310.31892655
102Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.31331926
103Notch signaling pathway_Homo sapiens_hsa043300.30319109
104Pyrimidine metabolism_Homo sapiens_hsa002400.30297490
105Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.27854445
106Cholinergic synapse_Homo sapiens_hsa047250.27350611
107Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.27158611
108Phosphatidylinositol signaling system_Homo sapiens_hsa040700.26730724
109Regulation of actin cytoskeleton_Homo sapiens_hsa048100.26728138
110Sphingolipid signaling pathway_Homo sapiens_hsa040710.25707686
111mRNA surveillance pathway_Homo sapiens_hsa030150.25223999
112RNA transport_Homo sapiens_hsa030130.24156750
113Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.23575705
114FoxO signaling pathway_Homo sapiens_hsa040680.23564616
115Vascular smooth muscle contraction_Homo sapiens_hsa042700.23181858
116MAPK signaling pathway_Homo sapiens_hsa040100.22763985
117Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.21615063
118Cell cycle_Homo sapiens_hsa041100.20416042
119Systemic lupus erythematosus_Homo sapiens_hsa053220.20347327
120HIF-1 signaling pathway_Homo sapiens_hsa040660.19350489
121Calcium signaling pathway_Homo sapiens_hsa040200.18005546
122Basal transcription factors_Homo sapiens_hsa030220.18002767
123Pentose phosphate pathway_Homo sapiens_hsa000300.17550659
124Protein export_Homo sapiens_hsa030600.17256970
125Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.16761773
126Inositol phosphate metabolism_Homo sapiens_hsa005620.15146179
127Prostate cancer_Homo sapiens_hsa052150.14451864
128mTOR signaling pathway_Homo sapiens_hsa041500.14305664
129Insulin resistance_Homo sapiens_hsa049310.14227032
130Adipocytokine signaling pathway_Homo sapiens_hsa049200.12840117

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