

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation by symbiont of host defense response (GO:0052509) | 6.38566823 |
| 2 | modulation by symbiont of host defense response (GO:0052031) | 6.38566823 |
| 3 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 6.38566823 |
| 4 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 6.38566823 |
| 5 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 6.38566823 |
| 6 | modulation by symbiont of host immune response (GO:0052553) | 6.38566823 |
| 7 | cellular response to exogenous dsRNA (GO:0071360) | 6.33915942 |
| 8 | positive regulation of chemokine biosynthetic process (GO:0045080) | 6.15731722 |
| 9 | intracellular pH reduction (GO:0051452) | 6.11702794 |
| 10 | fat-soluble vitamin biosynthetic process (GO:0042362) | 5.96988173 |
| 11 | regulation of T-helper 1 cell differentiation (GO:0045625) | 5.74708246 |
| 12 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.53018558 |
| 13 | negative regulation of type 2 immune response (GO:0002829) | 5.37327581 |
| 14 | regulation of T-helper 2 cell differentiation (GO:0045628) | 5.17713567 |
| 15 | microglial cell activation (GO:0001774) | 5.13720331 |
| 16 | cellular response to interferon-beta (GO:0035458) | 4.97634434 |
| 17 | pH reduction (GO:0045851) | 4.86493767 |
| 18 | natural killer cell mediated cytotoxicity (GO:0042267) | 4.81629254 |
| 19 | natural killer cell mediated immunity (GO:0002228) | 4.81629254 |
| 20 | positive regulation of monocyte chemotaxis (GO:0090026) | 4.81550314 |
| 21 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.70739516 |
| 22 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.70739516 |
| 23 | positive regulation of natural killer cell differentiation (GO:0032825) | 4.67849883 |
| 24 | response to host immune response (GO:0052572) | 4.65840597 |
| 25 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 4.65840597 |
| 26 | positive regulation of interferon-alpha production (GO:0032727) | 4.58925540 |
| 27 | positive regulation of T-helper 1 type immune response (GO:0002827) | 4.55742801 |
| 28 | regulation of chemokine biosynthetic process (GO:0045073) | 4.54923536 |
| 29 | regulation of phospholipase A2 activity (GO:0032429) | 4.52738547 |
| 30 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 4.50305776 |
| 31 | cellular extravasation (GO:0045123) | 4.41750514 |
| 32 | positive regulation of interleukin-17 production (GO:0032740) | 4.34351278 |
| 33 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.34017466 |
| 34 | immunoglobulin mediated immune response (GO:0016064) | 4.24687077 |
| 35 | regulation of interferon-alpha production (GO:0032647) | 4.24639911 |
| 36 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.21916392 |
| 37 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 4.16131179 |
| 38 | I-kappaB phosphorylation (GO:0007252) | 4.07583046 |
| 39 | response to host (GO:0075136) | 4.06292427 |
| 40 | response to host defenses (GO:0052200) | 4.06292427 |
| 41 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 4.06292427 |
| 42 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.98448030 |
| 43 | type I interferon signaling pathway (GO:0060337) | 3.95944944 |
| 44 | cellular response to type I interferon (GO:0071357) | 3.95944944 |
| 45 | macrophage activation involved in immune response (GO:0002281) | 3.94560046 |
| 46 | regulation of type 2 immune response (GO:0002828) | 3.89935276 |
| 47 | response to type I interferon (GO:0034340) | 3.88041672 |
| 48 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.84985201 |
| 49 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.63141287 |
| 50 | positive regulation of T-helper cell differentiation (GO:0045624) | 3.62322137 |
| 51 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.62315763 |
| 52 | myeloid dendritic cell differentiation (GO:0043011) | 3.61219690 |
| 53 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 3.59581235 |
| 54 | regulation of interferon-gamma biosynthetic process (GO:0045072) | 3.58233870 |
| 55 | pinocytosis (GO:0006907) | 3.58184907 |
| 56 | positive regulation of tyrosine phosphorylation of Stat1 protein (GO:0042511) | 3.56426574 |
| 57 | regulation of T-helper 1 type immune response (GO:0002825) | 3.52619514 |
| 58 | cellular response to interferon-gamma (GO:0071346) | 3.44729755 |
| 59 | response to interferon-beta (GO:0035456) | 3.42789928 |
| 60 | cellular response to interferon-alpha (GO:0035457) | 3.42112189 |
| 61 | regulation of monocyte chemotaxis (GO:0090025) | 3.39350458 |
| 62 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 3.36265829 |
| 63 | negative regulation of B cell mediated immunity (GO:0002713) | 3.33463300 |
| 64 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 3.33463300 |
| 65 | regulation of extracellular matrix disassembly (GO:0010715) | 3.31686739 |
| 66 | T cell migration (GO:0072678) | 3.27913371 |
| 67 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 3.24161979 |
| 68 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 3.21652673 |
| 69 | regulation of intracellular pH (GO:0051453) | 3.21383891 |
| 70 | regulation of lymphocyte migration (GO:2000401) | 3.19295710 |
| 71 | natural killer cell differentiation (GO:0001779) | 3.18442700 |
| 72 | regulation of cellular extravasation (GO:0002691) | 3.15165421 |
| 73 | positive regulation of type 2 immune response (GO:0002830) | 3.11781621 |
| 74 | regulation of natural killer cell differentiation (GO:0032823) | 3.11318636 |
| 75 | positive regulation of interleukin-12 production (GO:0032735) | 3.08357982 |
| 76 | cellular response to dsRNA (GO:0071359) | 3.08256929 |
| 77 | regulation of interleukin-17 production (GO:0032660) | 3.08012156 |
| 78 | positive regulation of response to biotic stimulus (GO:0002833) | 3.06858113 |
| 79 | natural killer cell activation (GO:0030101) | 3.05234700 |
| 80 | myeloid dendritic cell activation (GO:0001773) | 3.02443262 |
| 81 | response to interferon-gamma (GO:0034341) | 3.02124893 |
| 82 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.01976582 |
| 83 | positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516) | 2.99842329 |
| 84 | membrane raft organization (GO:0031579) | 2.98971240 |
| 85 | leukocyte mediated cytotoxicity (GO:0001909) | 2.97984093 |
| 86 | lymphocyte chemotaxis (GO:0048247) | 2.95495953 |
| 87 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.95267556 |
| 88 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.95267556 |
| 89 | positive regulation of antigen processing and presentation (GO:0002579) | 2.92018723 |
| 90 | actin nucleation (GO:0045010) | 2.88867859 |
| 91 | regulation of cellular pH (GO:0030641) | 2.88735313 |
| 92 | response to peptidoglycan (GO:0032494) | 2.88223899 |
| 93 | grooming behavior (GO:0007625) | 2.87278853 |
| 94 | regulation of B cell mediated immunity (GO:0002712) | 2.86953832 |
| 95 | macrophage activation (GO:0042116) | 2.85923614 |
| 96 | negative regulation of epidermal growth factor-activated receptor activity (GO:0007175) | 2.85738938 |
| 97 | B cell mediated immunity (GO:0019724) | 2.85575599 |
| 98 | regulation of natural killer cell activation (GO:0032814) | 2.85335810 |
| 99 | regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370) | 2.81827351 |
| 100 | sphingolipid catabolic process (GO:0030149) | 2.81470742 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 7.97487842 |
| 2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 6.35405659 |
| 3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.50646167 |
| 4 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 4.64010292 |
| 5 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 4.38753736 |
| 6 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.16679431 |
| 7 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.71657831 |
| 8 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.27287461 |
| 9 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.61845825 |
| 10 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.39709388 |
| 11 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.29307013 |
| 12 | * STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.24336772 |
| 13 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.14660724 |
| 14 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.09473591 |
| 15 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.06777875 |
| 16 | EGR1_19032775_ChIP-ChIP_M12_Human | 2.04452908 |
| 17 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.96228361 |
| 18 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.95250289 |
| 19 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.91982971 |
| 20 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.86895105 |
| 21 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.86168644 |
| 22 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.69696056 |
| 23 | GATA1_22025678_ChIP-Seq_K562_Human | 1.67690690 |
| 24 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.65665105 |
| 25 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.53081585 |
| 26 | SPI1_23127762_ChIP-Seq_K562_Human | 1.52002916 |
| 27 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.50617731 |
| 28 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.49895323 |
| 29 | MYB_26560356_Chip-Seq_TH2_Human | 1.46309500 |
| 30 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.33911173 |
| 31 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.28287145 |
| 32 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.24937074 |
| 33 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.23025741 |
| 34 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.21571968 |
| 35 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.20633510 |
| 36 | MAF_26560356_Chip-Seq_TH1_Human | 1.16630678 |
| 37 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.15156345 |
| 38 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.12118334 |
| 39 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.11743107 |
| 40 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.11156867 |
| 41 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.10934453 |
| 42 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.10725764 |
| 43 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.09970286 |
| 44 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.09687919 |
| 45 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.08311324 |
| 46 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.06915653 |
| 47 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.06494776 |
| 48 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.06069381 |
| 49 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.04311958 |
| 50 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.03720036 |
| 51 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.02937700 |
| 52 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 0.99828619 |
| 53 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.97677284 |
| 54 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.97278798 |
| 55 | RXR_22108803_ChIP-Seq_LS180_Human | 0.96423109 |
| 56 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 0.95780615 |
| 57 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 0.94360995 |
| 58 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.93748260 |
| 59 | GATA3_26560356_Chip-Seq_TH2_Human | 0.93236880 |
| 60 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.93119101 |
| 61 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.89271858 |
| 62 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.88680063 |
| 63 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.88408665 |
| 64 | MYB_26560356_Chip-Seq_TH1_Human | 0.87452011 |
| 65 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.86869070 |
| 66 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 0.86815724 |
| 67 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.85729005 |
| 68 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 0.84955185 |
| 69 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 0.84823149 |
| 70 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.84148404 |
| 71 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 0.80461216 |
| 72 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 0.80461216 |
| 73 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.79879109 |
| 74 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.78544781 |
| 75 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.78117480 |
| 76 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.77594597 |
| 77 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.77365896 |
| 78 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.76623776 |
| 79 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.75421558 |
| 80 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.74402156 |
| 81 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 0.74131698 |
| 82 | VDR_24763502_ChIP-Seq_THP-1_Human | 0.72738931 |
| 83 | OCT1_27270436_Chip-Seq_PROSTATE_Human | 0.72429486 |
| 84 | * PU_27001747_Chip-Seq_BMDM_Mouse | 0.71830655 |
| 85 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.71712544 |
| 86 | P300_19829295_ChIP-Seq_ESCs_Human | 0.69930115 |
| 87 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.69375544 |
| 88 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.69375544 |
| 89 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.68137677 |
| 90 | SCL_19346495_ChIP-Seq_HPC-7_Human | 0.67985383 |
| 91 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 0.67777969 |
| 92 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.67574801 |
| 93 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.64879600 |
| 94 | PU1_27457419_Chip-Seq_LIVER_Mouse | 0.64618365 |
| 95 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.63590164 |
| 96 | CJUN_26792858_Chip-Seq_BT549_Human | 0.63085203 |
| 97 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.62254691 |
| 98 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.61543770 |
| 99 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.61396140 |
| 100 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.60622650 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001835_abnormal_antigen_presentation | 7.17363746 |
| 2 | MP0004510_myositis | 4.38093009 |
| 3 | MP0006082_CNS_inflammation | 3.45563659 |
| 4 | MP0000685_abnormal_immune_system | 3.43662840 |
| 5 | MP0001790_abnormal_immune_system | 3.15101596 |
| 6 | MP0005387_immune_system_phenotype | 3.15101596 |
| 7 | MP0009785_altered_susceptibility_to | 3.14022397 |
| 8 | MP0002148_abnormal_hypersensitivity_rea | 3.02325508 |
| 9 | MP0005451_abnormal_body_composition | 2.82752983 |
| 10 | MP0010234_abnormal_vibrissa_follicle | 2.76319511 |
| 11 | MP0002452_abnormal_antigen_presenting | 2.57657185 |
| 12 | MP0005000_abnormal_immune_tolerance | 2.55423563 |
| 13 | MP0001800_abnormal_humoral_immune | 2.48024890 |
| 14 | MP0003436_decreased_susceptibility_to | 2.45995996 |
| 15 | MP0009046_muscle_twitch | 2.43487769 |
| 16 | MP0002419_abnormal_innate_immunity | 2.41689367 |
| 17 | MP0005025_abnormal_response_to | 2.39812428 |
| 18 | MP0005671_abnormal_response_to | 2.33576689 |
| 19 | MP0009764_decreased_sensitivity_to | 2.19862126 |
| 20 | MP0001873_stomach_inflammation | 2.13825748 |
| 21 | MP0001853_heart_inflammation | 2.11839596 |
| 22 | MP0001819_abnormal_immune_cell | 2.06873996 |
| 23 | MP0002723_abnormal_immune_serum | 2.03742090 |
| 24 | MP0000566_synostosis | 1.94192694 |
| 25 | MP0005623_abnormal_meninges_morphology | 1.94159555 |
| 26 | MP0003303_peritoneal_inflammation | 1.91297982 |
| 27 | MP0002420_abnormal_adaptive_immunity | 1.91297312 |
| 28 | MP0002405_respiratory_system_inflammati | 1.83921129 |
| 29 | MP0001958_emphysema | 1.65662203 |
| 30 | MP0009333_abnormal_splenocyte_physiolog | 1.63658671 |
| 31 | MP0003448_altered_tumor_morphology | 1.62677241 |
| 32 | MP0003075_altered_response_to | 1.61837919 |
| 33 | MP0005423_abnormal_somatic_nervous | 1.61551046 |
| 34 | MP0002006_tumorigenesis | 1.61489240 |
| 35 | MP0005645_abnormal_hypothalamus_physiol | 1.59592789 |
| 36 | MP0005464_abnormal_platelet_physiology | 1.55657184 |
| 37 | MP0002876_abnormal_thyroid_physiology | 1.49826833 |
| 38 | MP0005084_abnormal_gallbladder_morpholo | 1.44621911 |
| 39 | MP0002166_altered_tumor_susceptibility | 1.44584170 |
| 40 | MP0002396_abnormal_hematopoietic_system | 1.43248372 |
| 41 | MP0003045_fibrosis | 1.41402396 |
| 42 | MP0000716_abnormal_immune_system | 1.36790136 |
| 43 | MP0002933_joint_inflammation | 1.34328615 |
| 44 | MP0001845_abnormal_inflammatory_respons | 1.31618218 |
| 45 | MP0001440_abnormal_grooming_behavior | 1.31386727 |
| 46 | MP0005166_decreased_susceptibility_to | 1.30108725 |
| 47 | MP0009780_abnormal_chondrocyte_physiolo | 1.27204889 |
| 48 | MP0002398_abnormal_bone_marrow | 1.22347464 |
| 49 | MP0002138_abnormal_hepatobiliary_system | 1.19334918 |
| 50 | MP0003941_abnormal_skin_development | 1.19266096 |
| 51 | MP0001533_abnormal_skeleton_physiology | 1.18773844 |
| 52 | MP0000343_altered_response_to | 1.17758332 |
| 53 | MP0003453_abnormal_keratinocyte_physiol | 1.14241693 |
| 54 | MP0005360_urolithiasis | 1.13902604 |
| 55 | MP0008469_abnormal_protein_level | 1.11348241 |
| 56 | MP0002090_abnormal_vision | 1.11055944 |
| 57 | MP0000689_abnormal_spleen_morphology | 1.08304106 |
| 58 | MP0005310_abnormal_salivary_gland | 1.08086114 |
| 59 | MP0002429_abnormal_blood_cell | 1.07962513 |
| 60 | MP0004947_skin_inflammation | 1.05651841 |
| 61 | MP0003866_abnormal_defecation | 0.99590241 |
| 62 | MP0000858_altered_metastatic_potential | 0.99249672 |
| 63 | MP0000604_amyloidosis | 0.99082500 |
| 64 | MP0002722_abnormal_immune_system | 0.95294215 |
| 65 | MP0002998_abnormal_bone_remodeling | 0.90617011 |
| 66 | MP0002064_seizures | 0.88581003 |
| 67 | MP0003724_increased_susceptibility_to | 0.84766251 |
| 68 | MP0004859_abnormal_synaptic_plasticity | 0.82344538 |
| 69 | MP0001881_abnormal_mammary_gland | 0.81504302 |
| 70 | MP0009763_increased_sensitivity_to | 0.79761429 |
| 71 | MP0002168_other_aberrant_phenotype | 0.79150896 |
| 72 | MP0000470_abnormal_stomach_morphology | 0.77574514 |
| 73 | MP0004142_abnormal_muscle_tone | 0.75347509 |
| 74 | MP0000467_abnormal_esophagus_morphology | 0.74228234 |
| 75 | MP0003763_abnormal_thymus_physiology | 0.74187533 |
| 76 | MP0003638_abnormal_response/metabolism_ | 0.71824073 |
| 77 | MP0003091_abnormal_cell_migration | 0.71400602 |
| 78 | MP0010155_abnormal_intestine_physiology | 0.68940713 |
| 79 | MP0003690_abnormal_glial_cell | 0.68521558 |
| 80 | MP0005395_other_phenotype | 0.67388254 |
| 81 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.66328382 |
| 82 | MP0003329_amyloid_beta_deposits | 0.65876906 |
| 83 | MP0002136_abnormal_kidney_physiology | 0.65267088 |
| 84 | MP0002693_abnormal_pancreas_physiology | 0.65113192 |
| 85 | MP0001663_abnormal_digestive_system | 0.63596715 |
| 86 | MP0003787_abnormal_imprinting | 0.63204653 |
| 87 | MP0000920_abnormal_myelination | 0.60495882 |
| 88 | MP0003252_abnormal_bile_duct | 0.59577497 |
| 89 | MP0005248_abnormal_Harderian_gland | 0.57306721 |
| 90 | MP0003718_maternal_effect | 0.56777531 |
| 91 | MP0003186_abnormal_redox_activity | 0.56595649 |
| 92 | MP0005390_skeleton_phenotype | 0.54196548 |
| 93 | MP0005595_abnormal_vascular_smooth | 0.52799072 |
| 94 | MP0009745_abnormal_behavioral_response | 0.50319974 |
| 95 | MP0001851_eye_inflammation | 0.48175284 |
| 96 | MP0006138_congestive_heart_failure | 0.47603605 |
| 97 | MP0008874_decreased_physiological_sensi | 0.46092265 |
| 98 | MP0001348_abnormal_lacrimal_gland | 0.45802119 |
| 99 | MP0000598_abnormal_liver_morphology | 0.42983721 |
| 100 | MP0005165_increased_susceptibility_to | 0.42439455 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Chronic otitis media (HP:0000389) | 6.39864288 |
| 2 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 5.59705537 |
| 3 | Recurrent abscess formation (HP:0002722) | 5.47871385 |
| 4 | Vacuolated lymphocytes (HP:0001922) | 5.27504949 |
| 5 | Loss of speech (HP:0002371) | 5.22986865 |
| 6 | Increased cerebral lipofuscin (HP:0011813) | 5.22796900 |
| 7 | Recurrent bacterial skin infections (HP:0005406) | 4.97645785 |
| 8 | Hyperventilation (HP:0002883) | 4.73519836 |
| 9 | Conjugated hyperbilirubinemia (HP:0002908) | 4.43973710 |
| 10 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.06248295 |
| 11 | IgM deficiency (HP:0002850) | 3.61029682 |
| 12 | Progressive microcephaly (HP:0000253) | 3.55463865 |
| 13 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.54368483 |
| 14 | Eczematoid dermatitis (HP:0000976) | 3.54287184 |
| 15 | J-shaped sella turcica (HP:0002680) | 3.52955856 |
| 16 | Myositis (HP:0100614) | 3.51443425 |
| 17 | Azoospermia (HP:0000027) | 3.25634911 |
| 18 | Abnormality of liposaccharide metabolism (HP:0010968) | 3.23618733 |
| 19 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 3.23618733 |
| 20 | Abnormality of glycolipid metabolism (HP:0010969) | 3.23618733 |
| 21 | Recurrent skin infections (HP:0001581) | 3.19983542 |
| 22 | Recurrent viral infections (HP:0004429) | 3.19251243 |
| 23 | Polygenic inheritance (HP:0010982) | 3.14911835 |
| 24 | Chronic obstructive pulmonary disease (HP:0006510) | 3.07927543 |
| 25 | Obstructive lung disease (HP:0006536) | 3.07927543 |
| 26 | Amyloidosis (HP:0011034) | 3.05719106 |
| 27 | Basal ganglia calcification (HP:0002135) | 2.95487741 |
| 28 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.91721098 |
| 29 | Gingival bleeding (HP:0000225) | 2.88367758 |
| 30 | Increased IgM level (HP:0003496) | 2.88250895 |
| 31 | Chronic sinusitis (HP:0011109) | 2.84145624 |
| 32 | Abnormality of the lumbar spine (HP:0100712) | 2.80288470 |
| 33 | Vasculitis (HP:0002633) | 2.80201286 |
| 34 | Panhypogammaglobulinemia (HP:0003139) | 2.77669211 |
| 35 | Macular degeneration (HP:0000608) | 2.76249213 |
| 36 | Acrocyanosis (HP:0001063) | 2.75279276 |
| 37 | Recurrent bronchitis (HP:0002837) | 2.70942931 |
| 38 | Restrictive lung disease (HP:0002091) | 2.70467659 |
| 39 | Nephritis (HP:0000123) | 2.70133969 |
| 40 | Nasal polyposis (HP:0100582) | 2.64128147 |
| 41 | Prolonged partial thromboplastin time (HP:0003645) | 2.61916732 |
| 42 | Abnormality of complement system (HP:0005339) | 2.57169752 |
| 43 | Abolished electroretinogram (ERG) (HP:0000550) | 2.56945368 |
| 44 | Pustule (HP:0200039) | 2.56135799 |
| 45 | Xerostomia (HP:0000217) | 2.53825971 |
| 46 | Hypergammaglobulinemia (HP:0010702) | 2.53226691 |
| 47 | Absent frontal sinuses (HP:0002688) | 2.52977606 |
| 48 | Deformed sella turcica (HP:0002681) | 2.50315030 |
| 49 | Squamous cell carcinoma (HP:0002860) | 2.49382438 |
| 50 | Urethral obstruction (HP:0000796) | 2.48148296 |
| 51 | Recurrent fungal infections (HP:0002841) | 2.47085788 |
| 52 | Selective tooth agenesis (HP:0001592) | 2.46192079 |
| 53 | Gingivitis (HP:0000230) | 2.44751624 |
| 54 | Abnormality of the nasal mucosa (HP:0000433) | 2.43731558 |
| 55 | Mediastinal lymphadenopathy (HP:0100721) | 2.41461732 |
| 56 | Hemoptysis (HP:0002105) | 2.34987714 |
| 57 | Recurrent cutaneous fungal infections (HP:0011370) | 2.32408230 |
| 58 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.32408230 |
| 59 | Meningitis (HP:0001287) | 2.30814611 |
| 60 | IgA deficiency (HP:0002720) | 2.30539188 |
| 61 | Poor head control (HP:0002421) | 2.27998860 |
| 62 | Abnormality of the pleura (HP:0002103) | 2.25600646 |
| 63 | Acute myeloid leukemia (HP:0004808) | 2.24355522 |
| 64 | Abnormality of macrophages (HP:0004311) | 2.24073877 |
| 65 | Systemic lupus erythematosus (HP:0002725) | 2.22781727 |
| 66 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.21391869 |
| 67 | Mucopolysacchariduria (HP:0008155) | 2.21391869 |
| 68 | Agammaglobulinemia (HP:0004432) | 2.15004012 |
| 69 | Emphysema (HP:0002097) | 2.11764405 |
| 70 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.11434794 |
| 71 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.11434794 |
| 72 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.11434794 |
| 73 | IgG deficiency (HP:0004315) | 2.10284911 |
| 74 | Neonatal short-limb short stature (HP:0008921) | 2.08442346 |
| 75 | Autoimmune hemolytic anemia (HP:0001890) | 2.06943895 |
| 76 | Abnormal number of incisors (HP:0011064) | 2.05431213 |
| 77 | Gastrointestinal infarctions (HP:0005244) | 2.03180154 |
| 78 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.01795669 |
| 79 | Progressive visual loss (HP:0000529) | 2.00746334 |
| 80 | Abnormality of the sella turcica (HP:0002679) | 2.00699662 |
| 81 | Aplasia/Hypoplasia involving the sinuses (HP:0009120) | 1.95953640 |
| 82 | Periodontitis (HP:0000704) | 1.94420866 |
| 83 | Arterial thrombosis (HP:0004420) | 1.93985645 |
| 84 | Joint swelling (HP:0001386) | 1.92927847 |
| 85 | Oral leukoplakia (HP:0002745) | 1.92630254 |
| 86 | Pulmonary infiltrates (HP:0002113) | 1.92483595 |
| 87 | Osteolytic defects of the hand bones (HP:0009699) | 1.92167551 |
| 88 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.92167551 |
| 89 | Skin rash (HP:0000988) | 1.91910051 |
| 90 | Abnormal spermatogenesis (HP:0008669) | 1.91640413 |
| 91 | Polyneuropathy (HP:0001271) | 1.91624006 |
| 92 | Abnormality of the pericardium (HP:0001697) | 1.91142480 |
| 93 | Cheilitis (HP:0100825) | 1.90893484 |
| 94 | Interstitial pulmonary disease (HP:0006530) | 1.85136897 |
| 95 | Abnormality of the prostate (HP:0008775) | 1.84252443 |
| 96 | Cervical subluxation (HP:0003308) | 1.83291369 |
| 97 | Peritonitis (HP:0002586) | 1.81244532 |
| 98 | Hemangiomatosis (HP:0007461) | 1.79996649 |
| 99 | Tinnitus (HP:0000360) | 1.79896053 |
| 100 | Skin ulcer (HP:0200042) | 1.78960737 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP3K12 | 4.86112201 |
| 2 | BLK | 4.64651317 |
| 3 | MAP3K14 | 4.56363505 |
| 4 | EPHB1 | 3.46550565 |
| 5 | CDK19 | 3.13434711 |
| 6 | JAK3 | 2.80942410 |
| 7 | TYK2 | 2.78153765 |
| 8 | FGFR4 | 2.70723349 |
| 9 | KIT | 2.64131393 |
| 10 | FGFR3 | 2.28071709 |
| 11 | TBK1 | 2.28064442 |
| 12 | TAOK3 | 2.25109229 |
| 13 | JAK1 | 2.22570022 |
| 14 | RIPK4 | 2.22508953 |
| 15 | RIPK1 | 1.88287382 |
| 16 | EPHA3 | 1.87238359 |
| 17 | MYLK | 1.81083100 |
| 18 | IKBKE | 1.80449014 |
| 19 | IRAK4 | 1.72115488 |
| 20 | ITK | 1.68517540 |
| 21 | OXSR1 | 1.63306091 |
| 22 | EIF2AK2 | 1.59818826 |
| 23 | TAOK1 | 1.51155843 |
| 24 | TTK | 1.51087080 |
| 25 | FES | 1.38042045 |
| 26 | IKBKB | 1.35408640 |
| 27 | CSK | 1.34971391 |
| 28 | STK16 | 1.33841720 |
| 29 | CSF1R | 1.31372382 |
| 30 | MAP4K1 | 1.29588221 |
| 31 | SYK | 1.28941940 |
| 32 | EIF2AK1 | 1.28895624 |
| 33 | PAK4 | 1.19941508 |
| 34 | CSNK1A1L | 1.12262493 |
| 35 | PKN1 | 1.11814418 |
| 36 | JAK2 | 1.11204106 |
| 37 | BMX | 1.10905520 |
| 38 | FGR | 1.05375019 |
| 39 | MAP3K13 | 1.04062733 |
| 40 | MAP3K5 | 1.01233942 |
| 41 | ERN1 | 1.00106922 |
| 42 | CSNK1G3 | 0.91689010 |
| 43 | PBK | 0.83948597 |
| 44 | LRRK2 | 0.83671257 |
| 45 | GRK1 | 0.82688638 |
| 46 | LCK | 0.79165816 |
| 47 | TXK | 0.78478603 |
| 48 | CAMKK1 | 0.75834897 |
| 49 | DAPK3 | 0.74030705 |
| 50 | ALK | 0.73004820 |
| 51 | LYN | 0.72237640 |
| 52 | ATR | 0.70295019 |
| 53 | ABL2 | 0.66484680 |
| 54 | NUAK1 | 0.66457465 |
| 55 | TEC | 0.63066690 |
| 56 | BMPR2 | 0.60871683 |
| 57 | SIK1 | 0.60844063 |
| 58 | BTK | 0.59349594 |
| 59 | DAPK1 | 0.58880303 |
| 60 | STK10 | 0.58042687 |
| 61 | FLT3 | 0.54492788 |
| 62 | ILK | 0.53559251 |
| 63 | LATS2 | 0.53185329 |
| 64 | PDK1 | 0.50177121 |
| 65 | PRKCQ | 0.49863051 |
| 66 | PRKCD | 0.49300315 |
| 67 | CSNK1G1 | 0.48874537 |
| 68 | ZAP70 | 0.48694866 |
| 69 | CSNK1G2 | 0.46918101 |
| 70 | LATS1 | 0.44980360 |
| 71 | VRK1 | 0.44205184 |
| 72 | NTRK2 | 0.43089722 |
| 73 | HIPK2 | 0.40986670 |
| 74 | NTRK3 | 0.40561860 |
| 75 | ABL1 | 0.37946599 |
| 76 | DYRK1B | 0.37766827 |
| 77 | PDPK1 | 0.32807264 |
| 78 | IGF1R | 0.32720098 |
| 79 | PRKG2 | 0.32253750 |
| 80 | NLK | 0.31077415 |
| 81 | DAPK2 | 0.29547412 |
| 82 | IRAK3 | 0.28564797 |
| 83 | PKN2 | 0.28027149 |
| 84 | FYN | 0.27931177 |
| 85 | CHUK | 0.27741648 |
| 86 | MAP2K7 | 0.27280186 |
| 87 | KDR | 0.26079582 |
| 88 | ROCK2 | 0.25673138 |
| 89 | PTK2B | 0.25620486 |
| 90 | STK11 | 0.25561653 |
| 91 | SIK2 | 0.25201281 |
| 92 | ADRBK2 | 0.23907851 |
| 93 | BCR | 0.23677598 |
| 94 | ADRBK1 | 0.23162637 |
| 95 | WNK1 | 0.23087202 |
| 96 | DMPK | 0.22760946 |
| 97 | GRK6 | 0.22465679 |
| 98 | IRAK1 | 0.20989009 |
| 99 | NME1 | 0.19159139 |
| 100 | MST4 | 0.18484541 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.49998592 |
| 2 | Fatty acid elongation_Homo sapiens_hsa00062 | 3.29115549 |
| 3 | Allograft rejection_Homo sapiens_hsa05330 | 2.94529459 |
| 4 | Viral myocarditis_Homo sapiens_hsa05416 | 2.68782495 |
| 5 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.64387998 |
| 6 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.44018434 |
| 7 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.29582967 |
| 8 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.28243953 |
| 9 | Leishmaniasis_Homo sapiens_hsa05140 | 2.26715425 |
| 10 | Salmonella infection_Homo sapiens_hsa05132 | 2.21372324 |
| 11 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.21117530 |
| 12 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 2.11266745 |
| 13 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.01867754 |
| 14 | Measles_Homo sapiens_hsa05162 | 1.86506229 |
| 15 | Malaria_Homo sapiens_hsa05144 | 1.85537095 |
| 16 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.83856886 |
| 17 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.80831578 |
| 18 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.80250731 |
| 19 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.79419616 |
| 20 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.77403302 |
| 21 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.74982897 |
| 22 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.72284572 |
| 23 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.63732682 |
| 24 | Influenza A_Homo sapiens_hsa05164 | 1.62527209 |
| 25 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.57074770 |
| 26 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.56452405 |
| 27 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.54936514 |
| 28 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.54320996 |
| 29 | Lysosome_Homo sapiens_hsa04142 | 1.53778932 |
| 30 | Tuberculosis_Homo sapiens_hsa05152 | 1.49531243 |
| 31 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.47474006 |
| 32 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.47126607 |
| 33 | Apoptosis_Homo sapiens_hsa04210 | 1.36621795 |
| 34 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.35619847 |
| 35 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.35460316 |
| 36 | Shigellosis_Homo sapiens_hsa05131 | 1.34747830 |
| 37 | Homologous recombination_Homo sapiens_hsa03440 | 1.32401514 |
| 38 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.30422428 |
| 39 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.30039554 |
| 40 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.27040672 |
| 41 | Pertussis_Homo sapiens_hsa05133 | 1.26116347 |
| 42 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.20137394 |
| 43 | Hepatitis C_Homo sapiens_hsa05160 | 1.14034884 |
| 44 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.13480099 |
| 45 | Phagosome_Homo sapiens_hsa04145 | 1.13014952 |
| 46 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.11620255 |
| 47 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.08291684 |
| 48 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.05859240 |
| 49 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.04450182 |
| 50 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.01350497 |
| 51 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.00893090 |
| 52 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.93904717 |
| 53 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.89234376 |
| 54 | Legionellosis_Homo sapiens_hsa05134 | 0.87452915 |
| 55 | Hepatitis B_Homo sapiens_hsa05161 | 0.85315354 |
| 56 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.83935392 |
| 57 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.76298595 |
| 58 | Platelet activation_Homo sapiens_hsa04611 | 0.74474725 |
| 59 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.74296974 |
| 60 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.73127013 |
| 61 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.71149258 |
| 62 | ABC transporters_Homo sapiens_hsa02010 | 0.69313173 |
| 63 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.68888868 |
| 64 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.66318870 |
| 65 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.62918664 |
| 66 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.62724790 |
| 67 | Salivary secretion_Homo sapiens_hsa04970 | 0.61449292 |
| 68 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.60951557 |
| 69 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.53116842 |
| 70 | Amoebiasis_Homo sapiens_hsa05146 | 0.51176593 |
| 71 | Prion diseases_Homo sapiens_hsa05020 | 0.44469471 |
| 72 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.44284935 |
| 73 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.42825021 |
| 74 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.39567240 |
| 75 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.37852269 |
| 76 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.36118845 |
| 77 | Morphine addiction_Homo sapiens_hsa05032 | 0.32741151 |
| 78 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.31993322 |
| 79 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.29459454 |
| 80 | Other glycan degradation_Homo sapiens_hsa00511 | 0.29320633 |
| 81 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.27042845 |
| 82 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.26550082 |
| 83 | Circadian entrainment_Homo sapiens_hsa04713 | 0.26257452 |
| 84 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.26207329 |
| 85 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.25911057 |
| 86 | Mineral absorption_Homo sapiens_hsa04978 | 0.25827893 |
| 87 | Nicotine addiction_Homo sapiens_hsa05033 | 0.25374198 |
| 88 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.24388656 |
| 89 | GABAergic synapse_Homo sapiens_hsa04727 | 0.24338547 |
| 90 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.24085918 |
| 91 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.23210566 |
| 92 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.23038171 |
| 93 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.20620808 |
| 94 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.19499789 |
| 95 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.19453336 |
| 96 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.18350114 |
| 97 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.17499948 |
| 98 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.16780039 |
| 99 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.16374205 |
| 100 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.14082967 |

