Rank | Gene Set | Z-score |
---|---|---|
1 | alanine transport (GO:0032328) | 6.66042454 |
2 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 6.06167901 |
3 | cellular potassium ion homeostasis (GO:0030007) | 5.90644985 |
4 | C4-dicarboxylate transport (GO:0015740) | 5.89600826 |
5 | amino acid import (GO:0043090) | 5.84058576 |
6 | L-amino acid import (GO:0043092) | 5.80301605 |
7 | sodium ion export (GO:0071436) | 5.64385165 |
8 | L-serine transport (GO:0015825) | 5.40246835 |
9 | cell communication by electrical coupling (GO:0010644) | 5.17477536 |
10 | locomotory exploration behavior (GO:0035641) | 5.00900522 |
11 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 4.99819931 |
12 | positive regulation of cellular amide metabolic process (GO:0034250) | 4.98620547 |
13 | gamma-aminobutyric acid transport (GO:0015812) | 4.93415870 |
14 | neurotransmitter-gated ion channel clustering (GO:0072578) | 4.88809136 |
15 | serine transport (GO:0032329) | 4.67354830 |
16 | regulation of beta-amyloid formation (GO:1902003) | 4.64065037 |
17 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.62369735 |
18 | presynaptic membrane organization (GO:0097090) | 4.50372596 |
19 | regulation of synapse structural plasticity (GO:0051823) | 4.49131917 |
20 | cellular response to cholesterol (GO:0071397) | 4.48491713 |
21 | low-density lipoprotein particle remodeling (GO:0034374) | 4.44634002 |
22 | potassium ion import (GO:0010107) | 4.36674755 |
23 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 4.35410395 |
24 | regulation of synaptic vesicle transport (GO:1902803) | 4.34567209 |
25 | axon ensheathment in central nervous system (GO:0032291) | 4.26399432 |
26 | central nervous system myelination (GO:0022010) | 4.26399432 |
27 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 4.24552942 |
28 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 4.15201779 |
29 | cellular sodium ion homeostasis (GO:0006883) | 4.13256684 |
30 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 4.09788183 |
31 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 4.08699821 |
32 | chondroitin sulfate catabolic process (GO:0030207) | 4.06825373 |
33 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.99932667 |
34 | adenine nucleotide transport (GO:0051503) | 3.98188549 |
35 | protein localization to synapse (GO:0035418) | 3.94288786 |
36 | neuronal ion channel clustering (GO:0045161) | 3.92239114 |
37 | glial cell proliferation (GO:0014009) | 3.91322032 |
38 | neurotransmitter transport (GO:0006836) | 3.87550058 |
39 | dendritic spine morphogenesis (GO:0060997) | 3.87503167 |
40 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 3.83238489 |
41 | regulation of amyloid precursor protein catabolic process (GO:1902991) | 3.80787926 |
42 | potassium ion homeostasis (GO:0055075) | 3.80667370 |
43 | response to auditory stimulus (GO:0010996) | 3.77702554 |
44 | acidic amino acid transport (GO:0015800) | 3.77536887 |
45 | proline transport (GO:0015824) | 3.76543442 |
46 | cellular response to sterol (GO:0036315) | 3.75923664 |
47 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 3.75785473 |
48 | neuron-neuron synaptic transmission (GO:0007270) | 3.75568281 |
49 | positive regulation of dendritic spine development (GO:0060999) | 3.75150235 |
50 | neurotransmitter uptake (GO:0001504) | 3.72612325 |
51 | dermatan sulfate biosynthetic process (GO:0030208) | 3.72151108 |
52 | positive regulation of membrane potential (GO:0045838) | 3.71689061 |
53 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.69296152 |
54 | dermatan sulfate metabolic process (GO:0030205) | 3.68311812 |
55 | regulation of neurotransmitter levels (GO:0001505) | 3.66870733 |
56 | atrial cardiac muscle cell action potential (GO:0086014) | 3.64759988 |
57 | positive regulation of synapse maturation (GO:0090129) | 3.62571752 |
58 | transmission of nerve impulse (GO:0019226) | 3.60280887 |
59 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 3.60220760 |
60 | cerebellar granule cell differentiation (GO:0021707) | 3.59649143 |
61 | glutamate receptor signaling pathway (GO:0007215) | 3.56307734 |
62 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 3.51192912 |
63 | regulation of phospholipid biosynthetic process (GO:0071071) | 3.47375628 |
64 | regulation of neurotransmitter uptake (GO:0051580) | 3.47242401 |
65 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.45903302 |
66 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.43972177 |
67 | purine nucleotide transport (GO:0015865) | 3.43235025 |
68 | regulation of neurotransmitter transport (GO:0051588) | 3.42045554 |
69 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 3.41582159 |
70 | regulation of postsynaptic membrane potential (GO:0060078) | 3.41079588 |
71 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 3.40966859 |
72 | regulation of neurotransmitter secretion (GO:0046928) | 3.35378375 |
73 | neuronal action potential propagation (GO:0019227) | 3.34083875 |
74 | mechanosensory behavior (GO:0007638) | 3.33188870 |
75 | purine ribonucleotide transport (GO:0015868) | 3.30319024 |
76 | membrane depolarization during action potential (GO:0086010) | 3.29492099 |
77 | neuromuscular process controlling balance (GO:0050885) | 3.28421600 |
78 | auditory behavior (GO:0031223) | 3.27934165 |
79 | L-glutamate transport (GO:0015813) | 3.25784455 |
80 | positive regulation of triglyceride biosynthetic process (GO:0010867) | 3.25091846 |
81 | regulation of voltage-gated calcium channel activity (GO:1901385) | 3.22972800 |
82 | * negative regulation of astrocyte differentiation (GO:0048712) | 3.22246374 |
83 | neuromuscular synaptic transmission (GO:0007274) | 3.20732308 |
84 | regulation of synaptic plasticity (GO:0048167) | 3.20474934 |
85 | long-term synaptic potentiation (GO:0060291) | 3.19866637 |
86 | regulation of dendritic spine development (GO:0060998) | 3.19690321 |
87 | neuron cell-cell adhesion (GO:0007158) | 3.19422160 |
88 | blood vessel maturation (GO:0001955) | 3.19205159 |
89 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 3.18605546 |
90 | lens fiber cell development (GO:0070307) | 3.18583342 |
91 | cerebellar Purkinje cell differentiation (GO:0021702) | 3.18068672 |
92 | membrane depolarization (GO:0051899) | 3.17725491 |
93 | synaptic transmission, glutamatergic (GO:0035249) | 3.16332610 |
94 | regulation of cellular amide metabolic process (GO:0034248) | 3.14644000 |
95 | ovulation cycle (GO:0042698) | 3.12931993 |
96 | synaptic vesicle endocytosis (GO:0048488) | 3.10371308 |
97 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 3.09783581 |
98 | positive regulation of potassium ion transmembrane transport (GO:1901381) | 3.09182343 |
99 | neuromuscular process controlling posture (GO:0050884) | 3.08510338 |
100 | synaptic transmission (GO:0007268) | 3.06984212 |
101 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 3.06272368 |
102 | peripheral nervous system axon ensheathment (GO:0032292) | 3.06096432 |
103 | myelination in peripheral nervous system (GO:0022011) | 3.06096432 |
104 | cerebellar Purkinje cell layer development (GO:0021680) | 3.04933110 |
105 | exploration behavior (GO:0035640) | 3.02583641 |
106 | membrane hyperpolarization (GO:0060081) | 3.01692492 |
107 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 3.01532018 |
108 | astrocyte differentiation (GO:0048708) | 3.01494976 |
109 | regulation of dendritic spine morphogenesis (GO:0061001) | 3.01399366 |
110 | positive regulation of inositol phosphate biosynthetic process (GO:0060732) | 3.01037979 |
111 | regulation of synapse maturation (GO:0090128) | 3.00550288 |
112 | synaptic vesicle exocytosis (GO:0016079) | 3.00304605 |
113 | potassium ion transmembrane transport (GO:0071805) | 3.00140813 |
114 | cellular potassium ion transport (GO:0071804) | 3.00140813 |
115 | layer formation in cerebral cortex (GO:0021819) | 2.99372601 |
116 | synaptic vesicle maturation (GO:0016188) | 2.98520446 |
117 | negative regulation of sodium ion transport (GO:0010766) | 2.98211452 |
118 | regulation of synaptic transmission (GO:0050804) | 2.93625862 |
119 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 2.93513550 |
120 | adult walking behavior (GO:0007628) | 2.92959003 |
121 | regulation of respiratory system process (GO:0044065) | 2.88636461 |
122 | regulation of female receptivity (GO:0045924) | 2.88625879 |
123 | glutamate secretion (GO:0014047) | 2.87557449 |
124 | serotonin metabolic process (GO:0042428) | 2.86623621 |
125 | neurotransmitter secretion (GO:0007269) | 2.85775015 |
126 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 2.85494942 |
127 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 2.85293704 |
128 | L-amino acid transport (GO:0015807) | 2.82586556 |
129 | vocalization behavior (GO:0071625) | 2.82002423 |
130 | long-term memory (GO:0007616) | 2.81275611 |
131 | regulation of membrane repolarization (GO:0060306) | 2.80242963 |
132 | response to histamine (GO:0034776) | 2.80053814 |
133 | neuroblast proliferation (GO:0007405) | 2.78630125 |
134 | postsynaptic membrane organization (GO:0001941) | 2.75137359 |
135 | regulation of neuronal synaptic plasticity (GO:0048168) | 2.73863913 |
136 | positive regulation of sodium ion transmembrane transport (GO:1902307) | 2.70646075 |
137 | oligodendrocyte differentiation (GO:0048709) | 2.70532693 |
138 | regulation of glutamate receptor signaling pathway (GO:1900449) | 2.69348464 |
139 | reverse cholesterol transport (GO:0043691) | 2.69304351 |
140 | response to gravity (GO:0009629) | 2.65249635 |
141 | regulation of cholesterol biosynthetic process (GO:0045540) | 2.64846398 |
142 | glycine transport (GO:0015816) | 2.63108035 |
143 | membrane repolarization (GO:0086009) | 2.62711458 |
144 | neutral amino acid transport (GO:0015804) | 2.62459259 |
145 | dendrite morphogenesis (GO:0048813) | 2.60965299 |
146 | presynaptic membrane assembly (GO:0097105) | 2.58353745 |
147 | regulation of glomerular filtration (GO:0003093) | 2.56354824 |
148 | response to cholesterol (GO:0070723) | 2.56140269 |
149 | dicarboxylic acid transport (GO:0006835) | 2.55209284 |
150 | positive regulation of alcohol biosynthetic process (GO:1902932) | 2.54671129 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.92434351 |
2 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 3.29889171 |
3 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 3.08459487 |
4 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.95841199 |
5 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.93722372 |
6 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.71900976 |
7 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.69553715 |
8 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.69061621 |
9 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.68262107 |
10 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.66161311 |
11 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.66161311 |
12 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.63289411 |
13 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.60693613 |
14 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.59793850 |
15 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.51887298 |
16 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.47192430 |
17 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.42563874 |
18 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.35035155 |
19 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.34630363 |
20 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.25356307 |
21 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.23307048 |
22 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.11724101 |
23 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 2.10140161 |
24 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.04579009 |
25 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.99778852 |
26 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.74245849 |
27 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.74195267 |
28 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.69906289 |
29 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.69254607 |
30 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.68843105 |
31 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.65705651 |
32 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.60515712 |
33 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.59352963 |
34 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.54587946 |
35 | RXR_22108803_ChIP-Seq_LS180_Human | 1.54468417 |
36 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.52394840 |
37 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.48380258 |
38 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.47891155 |
39 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.46735876 |
40 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.44450668 |
41 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.38495473 |
42 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.37938069 |
43 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.35984284 |
44 | TP53_16413492_ChIP-PET_HCT116_Human | 1.35945663 |
45 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.35897608 |
46 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.31433562 |
47 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.30121304 |
48 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.26389821 |
49 | AR_25329375_ChIP-Seq_VCAP_Human | 1.25734843 |
50 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.25032511 |
51 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.24057849 |
52 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.22895328 |
53 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.22716223 |
54 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.22469405 |
55 | P300_19829295_ChIP-Seq_ESCs_Human | 1.21549219 |
56 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.17336335 |
57 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.16197721 |
58 | AR_19668381_ChIP-Seq_PC3_Human | 1.15316158 |
59 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.13905018 |
60 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.13131204 |
61 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.12909567 |
62 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.12837177 |
63 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.11452612 |
64 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.11374847 |
65 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.10470092 |
66 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.08737315 |
67 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.08671269 |
68 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.07994809 |
69 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.07988561 |
70 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.04447456 |
71 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.04321077 |
72 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.03364310 |
73 | STAT3_23295773_ChIP-Seq_U87_Human | 1.01862081 |
74 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.01711119 |
75 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.01640807 |
76 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.01455374 |
77 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.00641601 |
78 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.00545432 |
79 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.99430019 |
80 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.98994546 |
81 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 0.98214214 |
82 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.97937280 |
83 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 0.95908082 |
84 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.95078317 |
85 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.95067118 |
86 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.94641056 |
87 | * ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.93798040 |
88 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.91636998 |
89 | * RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 0.91603126 |
90 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.91390158 |
91 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.91370322 |
92 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.90851231 |
93 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.89797605 |
94 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.89340502 |
95 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.89277006 |
96 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.89277006 |
97 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.88487529 |
98 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.88307905 |
99 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.87779872 |
100 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.87732168 |
101 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.86155058 |
102 | TCF4_23295773_ChIP-Seq_U87_Human | 0.85123588 |
103 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.85102023 |
104 | * YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.84410998 |
105 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.84069243 |
106 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 0.83356681 |
107 | * TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.82856001 |
108 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.82513307 |
109 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.82436489 |
110 | * ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.81210048 |
111 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 0.80973335 |
112 | KDM2B_26808549_Chip-Seq_K562_Human | 0.80288833 |
113 | ZNF274_21170338_ChIP-Seq_K562_Hela | 0.79458508 |
114 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.79325070 |
115 | * NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.79320000 |
116 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.78806158 |
117 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.78222754 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003690_abnormal_glial_cell | 3.92429697 |
2 | MP0004859_abnormal_synaptic_plasticity | 3.66704803 |
3 | MP0003329_amyloid_beta_deposits | 3.45230275 |
4 | MP0005646_abnormal_pituitary_gland | 3.23882979 |
5 | MP0002254_reproductive_system_inflammat | 3.15622717 |
6 | MP0004858_abnormal_nervous_system | 2.88293606 |
7 | MP0009780_abnormal_chondrocyte_physiolo | 2.84881879 |
8 | MP0001486_abnormal_startle_reflex | 2.84145092 |
9 | MP0003635_abnormal_synaptic_transmissio | 2.83842243 |
10 | MP0004885_abnormal_endolymph | 2.80054669 |
11 | MP0009046_muscle_twitch | 2.71429510 |
12 | MP0005423_abnormal_somatic_nervous | 2.53248898 |
13 | MP0003880_abnormal_central_pattern | 2.48389719 |
14 | MP0001440_abnormal_grooming_behavior | 2.44843695 |
15 | MP0004270_analgesia | 2.43122390 |
16 | MP0002064_seizures | 2.35906319 |
17 | MP0009384_cardiac_valve_regurgitation | 2.33576733 |
18 | MP0009745_abnormal_behavioral_response | 2.32471393 |
19 | MP0001502_abnormal_circadian_rhythm | 2.18605332 |
20 | MP0002572_abnormal_emotion/affect_behav | 2.16033430 |
21 | MP0008569_lethality_at_weaning | 2.13168544 |
22 | MP0002063_abnormal_learning/memory/cond | 2.12826936 |
23 | MP0009840_abnormal_foam_cell | 2.08959347 |
24 | MP0000566_synostosis | 2.00481581 |
25 | MP0003279_aneurysm | 1.90053236 |
26 | MP0000604_amyloidosis | 1.89216222 |
27 | MP0001984_abnormal_olfaction | 1.86610094 |
28 | MP0003634_abnormal_glial_cell | 1.86506283 |
29 | MP0003136_yellow_coat_color | 1.85909157 |
30 | MP0002272_abnormal_nervous_system | 1.84200744 |
31 | MP0001968_abnormal_touch/_nociception | 1.84187742 |
32 | MP0003879_abnormal_hair_cell | 1.80433246 |
33 | MP0002736_abnormal_nociception_after | 1.79926590 |
34 | MP0003075_altered_response_to | 1.77542674 |
35 | MP0002733_abnormal_thermal_nociception | 1.71019163 |
36 | MP0002734_abnormal_mechanical_nocicepti | 1.70724350 |
37 | MP0005377_hearing/vestibular/ear_phenot | 1.66454515 |
38 | MP0003878_abnormal_ear_physiology | 1.66454515 |
39 | MP0002638_abnormal_pupillary_reflex | 1.65724639 |
40 | MP0003633_abnormal_nervous_system | 1.64571841 |
41 | MP0003787_abnormal_imprinting | 1.61852342 |
42 | MP0002557_abnormal_social/conspecific_i | 1.58089185 |
43 | MP0002067_abnormal_sensory_capabilities | 1.57739049 |
44 | MP0001501_abnormal_sleep_pattern | 1.56305626 |
45 | MP0003632_abnormal_nervous_system | 1.53057732 |
46 | MP0001485_abnormal_pinna_reflex | 1.49423758 |
47 | MP0001853_heart_inflammation | 1.48580588 |
48 | MP0003631_nervous_system_phenotype | 1.47749311 |
49 | MP0003183_abnormal_peptide_metabolism | 1.46434060 |
50 | MP0003011_delayed_dark_adaptation | 1.44612302 |
51 | MP0006276_abnormal_autonomic_nervous | 1.43375932 |
52 | MP0002909_abnormal_adrenal_gland | 1.37760677 |
53 | MP0005386_behavior/neurological_phenoty | 1.37742721 |
54 | MP0004924_abnormal_behavior | 1.37742721 |
55 | MP0003137_abnormal_impulse_conducting | 1.37351580 |
56 | MP0004811_abnormal_neuron_physiology | 1.35582695 |
57 | MP0004142_abnormal_muscle_tone | 1.34500604 |
58 | MP0005171_absent_coat_pigmentation | 1.33908173 |
59 | MP0000920_abnormal_myelination | 1.32129866 |
60 | MP0001970_abnormal_pain_threshold | 1.32096840 |
61 | MP0005551_abnormal_eye_electrophysiolog | 1.31246602 |
62 | MP0000778_abnormal_nervous_system | 1.30350224 |
63 | MP0004215_abnormal_myocardial_fiber | 1.29971891 |
64 | MP0002882_abnormal_neuron_morphology | 1.14101979 |
65 | MP0005645_abnormal_hypothalamus_physiol | 1.13715377 |
66 | MP0005253_abnormal_eye_physiology | 1.08996779 |
67 | MP0000955_abnormal_spinal_cord | 1.06428008 |
68 | MP0002066_abnormal_motor_capabilities/c | 1.06370910 |
69 | MP0008872_abnormal_physiological_respon | 1.05038482 |
70 | MP0005379_endocrine/exocrine_gland_phen | 1.03941625 |
71 | MP0002090_abnormal_vision | 1.02938826 |
72 | MP0001905_abnormal_dopamine_level | 0.98290647 |
73 | MP0005167_abnormal_blood-brain_barrier | 0.97597740 |
74 | MP0001963_abnormal_hearing_physiology | 0.97363636 |
75 | MP0002229_neurodegeneration | 0.96649448 |
76 | MP0001299_abnormal_eye_distance/ | 0.95321161 |
77 | MP0002152_abnormal_brain_morphology | 0.94986620 |
78 | MP0002127_abnormal_cardiovascular_syste | 0.93563021 |
79 | MP0002089_abnormal_postnatal_growth/wei | 0.91874786 |
80 | MP0002735_abnormal_chemical_nociception | 0.91172441 |
81 | MP0008877_abnormal_DNA_methylation | 0.89666970 |
82 | MP0001986_abnormal_taste_sensitivity | 0.89088949 |
83 | MP0000569_abnormal_digit_pigmentation | 0.88590787 |
84 | MP0001529_abnormal_vocalization | 0.88359139 |
85 | MP0003172_abnormal_lysosome_physiology | 0.87930818 |
86 | MP0002184_abnormal_innervation | 0.85486975 |
87 | MP0004742_abnormal_vestibular_system | 0.85194389 |
88 | MP0005332_abnormal_amino_acid | 0.81668141 |
89 | MP0000026_abnormal_inner_ear | 0.80744493 |
90 | MP0000049_abnormal_middle_ear | 0.79390241 |
91 | MP0004147_increased_porphyrin_level | 0.78393156 |
92 | MP0005595_abnormal_vascular_smooth | 0.77789283 |
93 | MP0003122_maternal_imprinting | 0.76177492 |
94 | MP0005166_decreased_susceptibility_to | 0.73549030 |
95 | MP0005535_abnormal_body_temperature | 0.72186226 |
96 | MP0004130_abnormal_muscle_cell | 0.71316564 |
97 | MP0004043_abnormal_pH_regulation | 0.70899177 |
98 | MP0006072_abnormal_retinal_apoptosis | 0.69845218 |
99 | MP0001177_atelectasis | 0.69055845 |
100 | MP0010386_abnormal_urinary_bladder | 0.68892666 |
101 | MP0008874_decreased_physiological_sensi | 0.68676172 |
102 | MP0004133_heterotaxia | 0.68401664 |
103 | MP0000751_myopathy | 0.67683814 |
104 | MP0002752_abnormal_somatic_nervous | 0.67636467 |
105 | MP0005174_abnormal_tail_pigmentation | 0.66345471 |
106 | MP0005647_abnormal_sex_gland | 0.64909006 |
107 | MP0003646_muscle_fatigue | 0.64277622 |
108 | MP0000631_abnormal_neuroendocrine_gland | 0.63643972 |
109 | MP0005165_increased_susceptibility_to | 0.63545189 |
110 | MP0002069_abnormal_eating/drinking_beha | 0.63150825 |
111 | MP0002653_abnormal_ependyma_morphology | 0.62432502 |
112 | MP0000647_abnormal_sebaceous_gland | 0.62097955 |
113 | MP0006292_abnormal_olfactory_placode | 0.59150761 |
114 | MP0002822_catalepsy | 0.58736434 |
115 | MP0000579_abnormal_nail_morphology | 0.55271608 |
116 | MP0003123_paternal_imprinting | 0.54264903 |
117 | MP0002876_abnormal_thyroid_physiology | 0.54220424 |
118 | MP0000639_abnormal_adrenal_gland | 0.52342947 |
119 | MP0010769_abnormal_survival | 0.52044191 |
120 | MP0003283_abnormal_digestive_organ | 0.51573743 |
121 | MP0010768_mortality/aging | 0.48792929 |
122 | MP0002082_postnatal_lethality | 0.48787897 |
123 | MP0010770_preweaning_lethality | 0.48787897 |
124 | MP0004085_abnormal_heartbeat | 0.48262222 |
125 | MP0001188_hyperpigmentation | 0.45931029 |
126 | MP0003956_abnormal_body_size | 0.45773341 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Aplasia involving bones of the extremities (HP:0009825) | 7.39542826 |
2 | Aplasia involving bones of the upper limbs (HP:0009823) | 7.39542826 |
3 | Aplasia of the phalanges of the hand (HP:0009802) | 7.39542826 |
4 | Megalencephaly (HP:0001355) | 6.38856569 |
5 | Neurofibrillary tangles (HP:0002185) | 5.54559242 |
6 | Febrile seizures (HP:0002373) | 5.19718224 |
7 | Atonic seizures (HP:0010819) | 4.65260936 |
8 | Diplopia (HP:0000651) | 4.50123673 |
9 | Abnormality of binocular vision (HP:0011514) | 4.50123673 |
10 | Hemiparesis (HP:0001269) | 4.27278869 |
11 | Hypoplastic left heart (HP:0004383) | 4.13313440 |
12 | Cerebral inclusion bodies (HP:0100314) | 4.12391748 |
13 | Abnormality of the axillary hair (HP:0100134) | 3.94022076 |
14 | Abnormality of secondary sexual hair (HP:0009888) | 3.94022076 |
15 | Increased circulating renin level (HP:0000848) | 3.75425645 |
16 | Hemiplegia (HP:0002301) | 3.74006660 |
17 | Focal motor seizures (HP:0011153) | 3.72461173 |
18 | Humeroradial synostosis (HP:0003041) | 3.69403010 |
19 | Synostosis involving the elbow (HP:0003938) | 3.69403010 |
20 | Ankle clonus (HP:0011448) | 3.60367054 |
21 | Absence seizures (HP:0002121) | 3.57892794 |
22 | Dialeptic seizures (HP:0011146) | 3.57602818 |
23 | Clumsiness (HP:0002312) | 3.39272664 |
24 | Peripheral hypomyelination (HP:0007182) | 3.37962918 |
25 | Split foot (HP:0001839) | 3.35684773 |
26 | Epileptic encephalopathy (HP:0200134) | 3.30767036 |
27 | Mixed hearing impairment (HP:0000410) | 3.26788496 |
28 | Limb dystonia (HP:0002451) | 3.25720428 |
29 | Back pain (HP:0003418) | 3.16052204 |
30 | Hypoplastic heart (HP:0001961) | 3.15983457 |
31 | Long nose (HP:0003189) | 3.11322188 |
32 | Supranuclear gaze palsy (HP:0000605) | 3.05866676 |
33 | Myokymia (HP:0002411) | 3.00972033 |
34 | Spastic gait (HP:0002064) | 2.97716929 |
35 | Short hallux (HP:0010109) | 2.94486665 |
36 | Action tremor (HP:0002345) | 2.93844079 |
37 | Abnormality of the dental pulp (HP:0006479) | 2.92736507 |
38 | Akinesia (HP:0002304) | 2.91845995 |
39 | Short middle phalanx of the 5th finger (HP:0004220) | 2.87868972 |
40 | Cerebral hypomyelination (HP:0006808) | 2.84575744 |
41 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.84277249 |
42 | Pseudobulbar signs (HP:0002200) | 2.80769025 |
43 | Tetraparesis (HP:0002273) | 2.79201249 |
44 | Broad alveolar ridges (HP:0000187) | 2.75492923 |
45 | Gaze-evoked nystagmus (HP:0000640) | 2.75089963 |
46 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 2.71101299 |
47 | Mutism (HP:0002300) | 2.70753552 |
48 | Adactyly (HP:0009776) | 2.70712085 |
49 | Status epilepticus (HP:0002133) | 2.70298752 |
50 | Torticollis (HP:0000473) | 2.69876915 |
51 | Annular pancreas (HP:0001734) | 2.63139438 |
52 | Abnormality of the middle phalanges of the toes (HP:0010183) | 2.62619000 |
53 | Obstructive sleep apnea (HP:0002870) | 2.62410255 |
54 | Narrow nasal bridge (HP:0000446) | 2.60858329 |
55 | Anxiety (HP:0000739) | 2.60785403 |
56 | Dysdiadochokinesis (HP:0002075) | 2.58966686 |
57 | Polydipsia (HP:0001959) | 2.58450713 |
58 | Abnormal drinking behavior (HP:0030082) | 2.58450713 |
59 | Hyperlipoproteinemia (HP:0010980) | 2.56694675 |
60 | Broad-based gait (HP:0002136) | 2.56620034 |
61 | Metabolic alkalosis (HP:0200114) | 2.55204472 |
62 | Epileptiform EEG discharges (HP:0011182) | 2.54698549 |
63 | Focal seizures (HP:0007359) | 2.51742888 |
64 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 2.46368961 |
65 | Poor eye contact (HP:0000817) | 2.46139047 |
66 | Fibular aplasia (HP:0002990) | 2.46068915 |
67 | Dry hair (HP:0011359) | 2.44420006 |
68 | Genetic anticipation (HP:0003743) | 2.43646364 |
69 | Progressive cerebellar ataxia (HP:0002073) | 2.42345614 |
70 | Confusion (HP:0001289) | 2.42246064 |
71 | Abnormality of permanent molar morphology (HP:0011071) | 2.39950971 |
72 | Abnormality of the dental root (HP:0006486) | 2.39950971 |
73 | Taurodontia (HP:0000679) | 2.39950971 |
74 | Hypoalphalipoproteinemia (HP:0003233) | 2.39903069 |
75 | Morphological abnormality of the inner ear (HP:0011390) | 2.35537684 |
76 | Focal dystonia (HP:0004373) | 2.33949558 |
77 | Hypokalemic alkalosis (HP:0001949) | 2.33394932 |
78 | Postural instability (HP:0002172) | 2.32827514 |
79 | Paraparesis (HP:0002385) | 2.31300950 |
80 | Sleep apnea (HP:0010535) | 2.29696124 |
81 | EEG with generalized epileptiform discharges (HP:0011198) | 2.26337697 |
82 | Tetraplegia (HP:0002445) | 2.26051062 |
83 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.24688343 |
84 | Atrioventricular block (HP:0001678) | 2.24509161 |
85 | Abnormality of molar (HP:0011077) | 2.23579422 |
86 | Abnormality of molar morphology (HP:0011070) | 2.23579422 |
87 | Papilledema (HP:0001085) | 2.22583284 |
88 | Impaired smooth pursuit (HP:0007772) | 2.21509630 |
89 | Abnormality of the corticospinal tract (HP:0002492) | 2.21082726 |
90 | Hypoplastic pelvis (HP:0008839) | 2.19910884 |
91 | Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376) | 2.18910251 |
92 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.17681524 |
93 | Maternal diabetes (HP:0009800) | 2.17453924 |
94 | Delusions (HP:0000746) | 2.16865479 |
95 | Onycholysis (HP:0001806) | 2.16174649 |
96 | Absent hair (HP:0002298) | 2.15586207 |
97 | Polyphagia (HP:0002591) | 2.14730535 |
98 | Hypomagnesemia (HP:0002917) | 2.14323868 |
99 | Hypsarrhythmia (HP:0002521) | 2.12199468 |
100 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.11257657 |
101 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.11257657 |
102 | Intention tremor (HP:0002080) | 2.10198480 |
103 | Truncal ataxia (HP:0002078) | 2.09767628 |
104 | Polyuria (HP:0000103) | 2.09341007 |
105 | Craniofacial dystonia (HP:0012179) | 2.09296111 |
106 | Urinary urgency (HP:0000012) | 2.08841519 |
107 | Scanning speech (HP:0002168) | 2.08270000 |
108 | Absent speech (HP:0001344) | 2.06860683 |
109 | Generalized tonic-clonic seizures (HP:0002069) | 2.06668859 |
110 | Amblyopia (HP:0000646) | 2.06030412 |
111 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 2.05347191 |
112 | Oligodactyly (hands) (HP:0001180) | 2.04861721 |
113 | Abnormality of cochlea (HP:0000375) | 2.03852413 |
114 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 2.02700921 |
115 | Abnormal social behavior (HP:0012433) | 2.02545721 |
116 | Impaired social interactions (HP:0000735) | 2.02545721 |
117 | Clonus (HP:0002169) | 2.01959299 |
118 | Rigidity (HP:0002063) | 2.01526994 |
119 | Abnormal eating behavior (HP:0100738) | 2.00989344 |
120 | Spastic tetraparesis (HP:0001285) | 1.98444117 |
121 | Selective tooth agenesis (HP:0001592) | 1.98229512 |
122 | Abnormality of ocular smooth pursuit (HP:0000617) | 1.97223338 |
123 | Visual hallucinations (HP:0002367) | 1.95671844 |
124 | Dysmetria (HP:0001310) | 1.95381153 |
125 | CNS hypomyelination (HP:0003429) | 1.94466654 |
126 | Anomalous pulmonary venous return (HP:0010772) | 1.93276043 |
127 | Heart block (HP:0012722) | 1.92198154 |
128 | Drooling (HP:0002307) | 1.91674309 |
129 | Choreoathetosis (HP:0001266) | 1.91304230 |
130 | Aplasia/Hypoplasia of the 5th finger (HP:0006262) | 1.88402751 |
131 | Abnormal urine output (HP:0012590) | 1.87966717 |
132 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 1.86616807 |
133 | Absent toe (HP:0010760) | 1.86603594 |
134 | Depression (HP:0000716) | 1.85663410 |
135 | Cutaneous syndactyly (HP:0012725) | 1.84980439 |
136 | Morphological abnormality of the pyramidal tract (HP:0002062) | 1.84758534 |
137 | Stereotypic behavior (HP:0000733) | 1.84001185 |
138 | Hyperglycinuria (HP:0003108) | 1.83638614 |
139 | Dementia (HP:0000726) | 1.80390862 |
140 | Fetal akinesia sequence (HP:0001989) | 1.79232765 |
141 | Microglossia (HP:0000171) | 1.77786895 |
142 | Ventricular fibrillation (HP:0001663) | 1.77403426 |
143 | Median cleft lip (HP:0000161) | 1.76610035 |
144 | Abnormality of magnesium homeostasis (HP:0004921) | 1.74500583 |
145 | Athetosis (HP:0002305) | 1.74449843 |
146 | Abnormality of renin-angiotensin system (HP:0000847) | 1.73980836 |
147 | Neonatal short-limb short stature (HP:0008921) | 1.72317371 |
148 | Anteriorly placed anus (HP:0001545) | 1.71919340 |
149 | Decreased central vision (HP:0007663) | 1.71800922 |
150 | Inability to walk (HP:0002540) | 1.71607526 |
151 | Excessive salivation (HP:0003781) | 1.71597179 |
152 | Coronal craniosynostosis (HP:0004440) | 1.69768574 |
153 | Abnormal atrioventricular conduction (HP:0005150) | 1.68765196 |
154 | Bradykinesia (HP:0002067) | 1.68028667 |
155 | Bronchomalacia (HP:0002780) | 1.67418379 |
156 | Abnormality of the columella (HP:0009929) | 1.66424984 |
157 | Slow-growing hair (HP:0002217) | 1.66402309 |
158 | Abnormality of hair growth rate (HP:0011363) | 1.66402309 |
159 | Abnormality of glycine metabolism (HP:0010895) | 1.66201465 |
160 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.66201465 |
161 | Hyperventilation (HP:0002883) | 1.64223295 |
162 | Exercise-induced myalgia (HP:0003738) | 1.64139632 |
163 | Alacrima (HP:0000522) | 1.63576373 |
164 | Mesangial abnormality (HP:0001966) | 1.63464454 |
165 | Limb ataxia (HP:0002070) | 1.63131343 |
166 | Lower limb muscle weakness (HP:0007340) | 1.61126909 |
167 | Hypoplastic nipples (HP:0002557) | 1.60797471 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EPHA4 | 5.66707386 |
2 | TNIK | 4.36859058 |
3 | LMTK2 | 4.27347432 |
4 | PHKG1 | 3.89182789 |
5 | PHKG2 | 3.89182789 |
6 | MUSK | 3.28999236 |
7 | NTRK2 | 3.25502666 |
8 | NTRK3 | 2.53252944 |
9 | PRKD3 | 2.12638614 |
10 | SIK1 | 2.01991403 |
11 | MAPK12 | 1.82826023 |
12 | CASK | 1.79783693 |
13 | PLK2 | 1.72916246 |
14 | MINK1 | 1.71305537 |
15 | TRIB3 | 1.68365479 |
16 | MAPK13 | 1.60150306 |
17 | PRKCG | 1.43156588 |
18 | MAP3K4 | 1.40545127 |
19 | TYRO3 | 1.38013800 |
20 | SGK494 | 1.33165579 |
21 | SGK223 | 1.33165579 |
22 | FRK | 1.31835785 |
23 | SGK2 | 1.31582722 |
24 | PRPF4B | 1.30975298 |
25 | PAK6 | 1.28200731 |
26 | MAP2K7 | 1.27616875 |
27 | NEK6 | 1.24915204 |
28 | MAP3K9 | 1.24436241 |
29 | MARK1 | 1.24429958 |
30 | FGFR2 | 1.18591987 |
31 | MAPK7 | 1.15584273 |
32 | NTRK1 | 1.13858369 |
33 | FGR | 1.07951480 |
34 | SGK3 | 1.07624094 |
35 | CDK5 | 1.07586967 |
36 | CAMKK1 | 1.06489225 |
37 | PINK1 | 1.06090274 |
38 | IRAK3 | 1.00561486 |
39 | CAMKK2 | 0.91758096 |
40 | DAPK1 | 0.89071820 |
41 | STK38 | 0.88973418 |
42 | MAPK15 | 0.86685130 |
43 | DYRK1A | 0.85463686 |
44 | ADRBK1 | 0.85220304 |
45 | PRKCE | 0.83870702 |
46 | MAP3K13 | 0.83283306 |
47 | FES | 0.82841530 |
48 | CAMK2A | 0.82071775 |
49 | STK11 | 0.81750837 |
50 | KSR2 | 0.80477925 |
51 | ADRBK2 | 0.78792573 |
52 | DAPK2 | 0.77032310 |
53 | PRKCH | 0.74506514 |
54 | WNK4 | 0.69542751 |
55 | MAPK10 | 0.69121583 |
56 | RIPK1 | 0.69108760 |
57 | OXSR1 | 0.68896832 |
58 | WNK3 | 0.68332389 |
59 | BMX | 0.67190349 |
60 | BMPR2 | 0.66217505 |
61 | PNCK | 0.65822253 |
62 | ARAF | 0.65181930 |
63 | CAMK2G | 0.64870788 |
64 | WNK1 | 0.64812874 |
65 | DDR2 | 0.64450768 |
66 | ROCK1 | 0.64429861 |
67 | CAMK1G | 0.63733960 |
68 | CDK15 | 0.63555969 |
69 | TNK2 | 0.63050766 |
70 | PAK3 | 0.62958282 |
71 | CAMK4 | 0.61977118 |
72 | MAP2K4 | 0.61700479 |
73 | CSNK1G2 | 0.61417252 |
74 | ROCK2 | 0.59977978 |
75 | ALK | 0.59430769 |
76 | CDK18 | 0.59392583 |
77 | RIPK4 | 0.58465060 |
78 | SGK1 | 0.57536428 |
79 | CDC42BPA | 0.57162931 |
80 | INSRR | 0.56995818 |
81 | PRKCZ | 0.55402579 |
82 | FGFR1 | 0.55174956 |
83 | CDK11A | 0.53296082 |
84 | MAP3K2 | 0.53095418 |
85 | PDPK1 | 0.51126899 |
86 | PRKCA | 0.50994756 |
87 | CAMK1 | 0.50277383 |
88 | RPS6KA3 | 0.49542760 |
89 | UHMK1 | 0.48397470 |
90 | CDK3 | 0.48329396 |
91 | GRK6 | 0.48276856 |
92 | GRK1 | 0.48121348 |
93 | CDK14 | 0.47164165 |
94 | STK39 | 0.46403358 |
95 | GRK5 | 0.46197971 |
96 | PRKACA | 0.46181933 |
97 | IGF1R | 0.45949625 |
98 | MAPKAPK5 | 0.45533414 |
99 | CSNK1A1 | 0.45495668 |
100 | SIK2 | 0.44597020 |
101 | TAOK2 | 0.44409727 |
102 | ERBB2 | 0.44409332 |
103 | KSR1 | 0.43653559 |
104 | CCNB1 | 0.43389542 |
105 | CAMK2B | 0.43367895 |
106 | CSNK1D | 0.43084111 |
107 | PRKACG | 0.42779912 |
108 | PRKCQ | 0.41925138 |
109 | CDK19 | 0.41805874 |
110 | PRKD2 | 0.41689631 |
111 | PRKG1 | 0.41144782 |
112 | FYN | 0.41070076 |
113 | PDGFRA | 0.40671040 |
114 | PDK1 | 0.40255527 |
115 | MAP4K2 | 0.39841951 |
116 | PKN1 | 0.39564420 |
117 | SRC | 0.39356247 |
118 | LATS2 | 0.37930555 |
119 | PIK3CA | 0.36755867 |
120 | CAMK2D | 0.36677867 |
121 | PRKD1 | 0.36525529 |
122 | PRKAA2 | 0.35966430 |
123 | MARK2 | 0.35222062 |
124 | MAP3K7 | 0.35098476 |
125 | PBK | 0.34434337 |
126 | MAP2K1 | 0.34070824 |
127 | BRSK1 | 0.32430856 |
128 | MAP2K6 | 0.31753097 |
129 | MAPK4 | 0.31062220 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nitrogen metabolism_Homo sapiens_hsa00910 | 4.78096994 |
2 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 4.56658310 |
3 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 3.51664185 |
4 | Nicotine addiction_Homo sapiens_hsa05033 | 2.85937911 |
5 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.31747916 |
6 | Fatty acid metabolism_Homo sapiens_hsa01212 | 2.25968698 |
7 | GABAergic synapse_Homo sapiens_hsa04727 | 2.16578936 |
8 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 2.09174182 |
9 | Salivary secretion_Homo sapiens_hsa04970 | 2.01389392 |
10 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.84431627 |
11 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.75992067 |
12 | Circadian entrainment_Homo sapiens_hsa04713 | 1.71714789 |
13 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.70497523 |
14 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.68825659 |
15 | Insulin secretion_Homo sapiens_hsa04911 | 1.67098152 |
16 | Morphine addiction_Homo sapiens_hsa05032 | 1.61581847 |
17 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.48909539 |
18 | Long-term potentiation_Homo sapiens_hsa04720 | 1.47262288 |
19 | Olfactory transduction_Homo sapiens_hsa04740 | 1.44120647 |
20 | Bile secretion_Homo sapiens_hsa04976 | 1.34269769 |
21 | Cocaine addiction_Homo sapiens_hsa05030 | 1.34178929 |
22 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.29433414 |
23 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.21135289 |
24 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.20797605 |
25 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.17686772 |
26 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.17497540 |
27 | Circadian rhythm_Homo sapiens_hsa04710 | 1.16042213 |
28 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.15131574 |
29 | Phototransduction_Homo sapiens_hsa04744 | 1.14874126 |
30 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.10787073 |
31 | Mineral absorption_Homo sapiens_hsa04978 | 1.09821045 |
32 | Taste transduction_Homo sapiens_hsa04742 | 1.07886130 |
33 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 1.07390239 |
34 | Long-term depression_Homo sapiens_hsa04730 | 1.06669890 |
35 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.06562958 |
36 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.03999859 |
37 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.01021508 |
38 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.99393713 |
39 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.98996602 |
40 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.98524083 |
41 | Histidine metabolism_Homo sapiens_hsa00340 | 0.97847557 |
42 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.95969012 |
43 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.93020752 |
44 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.92808822 |
45 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.92315753 |
46 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.92106742 |
47 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.90919160 |
48 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.89713614 |
49 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.89451878 |
50 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.86672892 |
51 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.86519322 |
52 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.86411364 |
53 | Gap junction_Homo sapiens_hsa04540 | 0.86032787 |
54 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.84049443 |
55 | Renin secretion_Homo sapiens_hsa04924 | 0.83269302 |
56 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.82537560 |
57 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.79472978 |
58 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.78738809 |
59 | Melanogenesis_Homo sapiens_hsa04916 | 0.78722213 |
60 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.78044515 |
61 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.74723904 |
62 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.74310663 |
63 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.72355583 |
64 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.71867375 |
65 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.71287930 |
66 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.69937946 |
67 | Glioma_Homo sapiens_hsa05214 | 0.69760983 |
68 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.69564461 |
69 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.69259844 |
70 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.69042279 |
71 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.67426535 |
72 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.66881651 |
73 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.66538713 |
74 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.65315536 |
75 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.64560874 |
76 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.64460445 |
77 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.61377861 |
78 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.60485662 |
79 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.60073966 |
80 | Peroxisome_Homo sapiens_hsa04146 | 0.59109921 |
81 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.59100826 |
82 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.58269513 |
83 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.57921084 |
84 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.57415135 |
85 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.56299783 |
86 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.55679820 |
87 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.55209477 |
88 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.55190637 |
89 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.54027853 |
90 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.53737596 |
91 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.53204946 |
92 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.53007768 |
93 | Axon guidance_Homo sapiens_hsa04360 | 0.52004372 |
94 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.50968704 |
95 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.50267873 |
96 | Sulfur relay system_Homo sapiens_hsa04122 | 0.49682601 |
97 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.49349913 |
98 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.47892120 |
99 | Prion diseases_Homo sapiens_hsa05020 | 0.46698528 |
100 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.45479300 |
101 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.42747704 |
102 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.42563800 |
103 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.42177628 |
104 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.42132354 |
105 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.41826891 |
106 | Lysosome_Homo sapiens_hsa04142 | 0.41216923 |
107 | Alzheimers disease_Homo sapiens_hsa05010 | 0.40978900 |
108 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.40559920 |
109 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.40314605 |
110 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.40215181 |
111 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.39841978 |
112 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.38785510 |
113 | ABC transporters_Homo sapiens_hsa02010 | 0.38707779 |
114 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.38697147 |
115 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.38521353 |
116 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.37751737 |
117 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.34886359 |
118 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.34086769 |
119 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.33571344 |
120 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.31646822 |
121 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.31505105 |
122 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.31392499 |
123 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.29026191 |
124 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.28014591 |
125 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.27580501 |
126 | Alcoholism_Homo sapiens_hsa05034 | 0.26003030 |
127 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.25805772 |
128 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.23947763 |