

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | behavioral response to nicotine (GO:0035095) | 7.54426903 |
| 2 | glycerophospholipid catabolic process (GO:0046475) | 6.76146386 |
| 3 | adaptation of signaling pathway (GO:0023058) | 6.52113364 |
| 4 | positive regulation of action potential (GO:0045760) | 6.48951831 |
| 5 | synaptic transmission, dopaminergic (GO:0001963) | 6.44664288 |
| 6 | regulation of synapse structural plasticity (GO:0051823) | 6.11320752 |
| 7 | prepulse inhibition (GO:0060134) | 6.10606918 |
| 8 | establishment of mitochondrion localization (GO:0051654) | 5.84121081 |
| 9 | pyrimidine nucleobase catabolic process (GO:0006208) | 5.83080384 |
| 10 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 5.75779415 |
| 11 | locomotory exploration behavior (GO:0035641) | 5.53992327 |
| 12 | mitochondrion transport along microtubule (GO:0047497) | 5.49976245 |
| 13 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 5.49976245 |
| 14 | adenosine receptor signaling pathway (GO:0001973) | 5.49206039 |
| 15 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 5.38796316 |
| 16 | striatum development (GO:0021756) | 5.35380916 |
| 17 | synaptic vesicle maturation (GO:0016188) | 5.32577068 |
| 18 | negative regulation of axon guidance (GO:1902668) | 5.29736628 |
| 19 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 5.20856552 |
| 20 | head development (GO:0060322) | 5.16538141 |
| 21 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 5.13258344 |
| 22 | response to amphetamine (GO:0001975) | 4.95975067 |
| 23 | vocalization behavior (GO:0071625) | 4.89997327 |
| 24 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 4.88595644 |
| 25 | auditory behavior (GO:0031223) | 4.86980036 |
| 26 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 4.84671285 |
| 27 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 4.73585896 |
| 28 | dopamine receptor signaling pathway (GO:0007212) | 4.72901008 |
| 29 | regulation of glutamate receptor signaling pathway (GO:1900449) | 4.68984253 |
| 30 | regulation of neuronal synaptic plasticity (GO:0048168) | 4.66191338 |
| 31 | behavioral response to cocaine (GO:0048148) | 4.63823041 |
| 32 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 4.62225099 |
| 33 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 4.59504250 |
| 34 | nucleobase catabolic process (GO:0046113) | 4.59154847 |
| 35 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 4.57271575 |
| 36 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 4.55735935 |
| 37 | regulation of action potential (GO:0098900) | 4.51950253 |
| 38 | neurotransmitter-gated ion channel clustering (GO:0072578) | 4.49295719 |
| 39 | positive regulation of neurotransmitter transport (GO:0051590) | 4.48631067 |
| 40 | regulation of glutamate secretion (GO:0014048) | 4.44345751 |
| 41 | regulation of dendritic spine morphogenesis (GO:0061001) | 4.44186020 |
| 42 | regulation of catecholamine uptake involved in synaptic transmission (GO:0051940) | 4.36089332 |
| 43 | regulation of dopamine uptake involved in synaptic transmission (GO:0051584) | 4.36089332 |
| 44 | detection of calcium ion (GO:0005513) | 4.32802202 |
| 45 | activated T cell proliferation (GO:0050798) | 4.31122700 |
| 46 | regulation of female receptivity (GO:0045924) | 4.28398995 |
| 47 | cAMP catabolic process (GO:0006198) | 4.27975704 |
| 48 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 4.27469931 |
| 49 | synaptic vesicle exocytosis (GO:0016079) | 4.24937779 |
| 50 | activation of MAPKKK activity (GO:0000185) | 4.18406980 |
| 51 | synapse assembly (GO:0007416) | 4.16394709 |
| 52 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 4.14632889 |
| 53 | neuromuscular process controlling balance (GO:0050885) | 4.14443289 |
| 54 | response to auditory stimulus (GO:0010996) | 4.14322315 |
| 55 | substrate-independent telencephalic tangential migration (GO:0021826) | 4.13979980 |
| 56 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 4.13979980 |
| 57 | neurotransmitter secretion (GO:0007269) | 4.13281333 |
| 58 | protein localization to synapse (GO:0035418) | 4.11877553 |
| 59 | neuron-neuron synaptic transmission (GO:0007270) | 4.11675635 |
| 60 | dendritic spine morphogenesis (GO:0060997) | 4.10376475 |
| 61 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.07365007 |
| 62 | exploration behavior (GO:0035640) | 4.07347292 |
| 63 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 4.03305394 |
| 64 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 4.03055489 |
| 65 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 4.02511069 |
| 66 | positive regulation of neurotransmitter secretion (GO:0001956) | 4.00520054 |
| 67 | axonal fasciculation (GO:0007413) | 3.99379903 |
| 68 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.90551494 |
| 69 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339) | 3.90072257 |
| 70 | regulation of cilium movement (GO:0003352) | 3.89515684 |
| 71 | long-term memory (GO:0007616) | 3.89050808 |
| 72 | phospholipase C-activating dopamine receptor signaling pathway (GO:0060158) | 3.88279387 |
| 73 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 3.88057833 |
| 74 | regulation of neurotransmitter uptake (GO:0051580) | 3.86532761 |
| 75 | synaptic transmission, cholinergic (GO:0007271) | 3.85248860 |
| 76 | synaptic transmission, glutamatergic (GO:0035249) | 3.81625883 |
| 77 | transmission of nerve impulse (GO:0019226) | 3.81062686 |
| 78 | positive regulation of membrane potential (GO:0045838) | 3.80683826 |
| 79 | neuronal ion channel clustering (GO:0045161) | 3.80163239 |
| 80 | female mating behavior (GO:0060180) | 3.78319793 |
| 81 | cyclic nucleotide catabolic process (GO:0009214) | 3.76323417 |
| 82 | layer formation in cerebral cortex (GO:0021819) | 3.73311706 |
| 83 | gamma-aminobutyric acid transport (GO:0015812) | 3.71752976 |
| 84 | behavioral fear response (GO:0001662) | 3.70702031 |
| 85 | behavioral defense response (GO:0002209) | 3.70702031 |
| 86 | regulation of postsynaptic membrane potential (GO:0060078) | 3.69818185 |
| 87 | visual learning (GO:0008542) | 3.67391348 |
| 88 | regulation of protein kinase A signaling (GO:0010738) | 3.67044289 |
| 89 | adult walking behavior (GO:0007628) | 3.64067049 |
| 90 | regulation of synaptic plasticity (GO:0048167) | 3.63770885 |
| 91 | neuronal action potential propagation (GO:0019227) | 3.63520527 |
| 92 | peristalsis (GO:0030432) | 3.62638805 |
| 93 | epithelial cell differentiation involved in kidney development (GO:0035850) | 3.61218114 |
| 94 | neuron recognition (GO:0008038) | 3.60499957 |
| 95 | neuromuscular process controlling posture (GO:0050884) | 3.59578380 |
| 96 | activation of protein kinase A activity (GO:0034199) | 3.59560571 |
| 97 | regulation of axon guidance (GO:1902667) | 3.59535457 |
| 98 | regulation of synaptic vesicle transport (GO:1902803) | 3.59403953 |
| 99 | response to histamine (GO:0034776) | 3.58707194 |
| 100 | mechanosensory behavior (GO:0007638) | 3.56576560 |
| 101 | negative regulation of dendrite development (GO:2000171) | 3.56085583 |
| 102 | regulation of dopamine secretion (GO:0014059) | 3.55612103 |
| 103 | regulation of norepinephrine secretion (GO:0014061) | 3.54884354 |
| 104 | cAMP metabolic process (GO:0046058) | 3.54651780 |
| 105 | glutamate receptor signaling pathway (GO:0007215) | 3.53944660 |
| 106 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 3.52769171 |
| 107 | axon extension involved in axon guidance (GO:0048846) | 3.52769171 |
| 108 | membrane hyperpolarization (GO:0060081) | 3.50852792 |
| 109 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.50004700 |
| 110 | neuronal action potential (GO:0019228) | 3.48362882 |
| 111 | regulation of synaptic transmission, GABAergic (GO:0032228) | 3.47470788 |
| 112 | response to amine (GO:0014075) | 3.46601628 |
| 113 | regulation of feeding behavior (GO:0060259) | 3.46210382 |
| 114 | mating behavior (GO:0007617) | 3.46017199 |
| 115 | visual behavior (GO:0007632) | 3.45806543 |
| 116 | regulation of voltage-gated calcium channel activity (GO:1901385) | 3.44818898 |
| 117 | negative regulation of amino acid transport (GO:0051956) | 3.44545884 |
| 118 | regulation of dendritic spine development (GO:0060998) | 3.43496813 |
| 119 | regulation of synapse maturation (GO:0090128) | 3.42694070 |
| 120 | long-term synaptic potentiation (GO:0060291) | 3.42420611 |
| 121 | membrane depolarization during action potential (GO:0086010) | 3.39033652 |
| 122 | organelle transport along microtubule (GO:0072384) | 3.38447943 |
| 123 | positive regulation of synapse maturation (GO:0090129) | 3.37731971 |
| 124 | platelet dense granule organization (GO:0060155) | 3.37608867 |
| 125 | fear response (GO:0042596) | 3.36580672 |
| 126 | regulation of microtubule-based movement (GO:0060632) | 3.36251738 |
| 127 | neuron cell-cell adhesion (GO:0007158) | 3.34507160 |
| 128 | glutamate secretion (GO:0014047) | 3.33818105 |
| 129 | positive regulation of mitochondrial fission (GO:0090141) | 3.29855492 |
| 130 | glycine transport (GO:0015816) | 3.28730141 |
| 131 | postsynaptic membrane organization (GO:0001941) | 3.28474843 |
| 132 | learning (GO:0007612) | 3.27214548 |
| 133 | vesicle transport along microtubule (GO:0047496) | 3.26657935 |
| 134 | drinking behavior (GO:0042756) | 3.22970681 |
| 135 | regulation of neurotransmitter levels (GO:0001505) | 3.20682407 |
| 136 | negative regulation of amine transport (GO:0051953) | 3.19802416 |
| 137 | axoneme assembly (GO:0035082) | 3.19049006 |
| 138 | cAMP biosynthetic process (GO:0006171) | 3.17098375 |
| 139 | neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976) | 3.16928894 |
| 140 | regulation of synaptic transmission, dopaminergic (GO:0032225) | 3.16653355 |
| 141 | positive regulation of oligodendrocyte differentiation (GO:0048714) | 3.14832629 |
| 142 | protein polyglutamylation (GO:0018095) | 3.13858342 |
| 143 | synapse organization (GO:0050808) | 3.12894652 |
| 144 | negative regulation of JUN kinase activity (GO:0043508) | 3.11528868 |
| 145 | ganglion development (GO:0061548) | 3.05434598 |
| 146 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.04437922 |
| 147 | cerebellar Purkinje cell differentiation (GO:0021702) | 2.98833735 |
| 148 | neurofilament cytoskeleton organization (GO:0060052) | 2.98599390 |
| 149 | calcium ion-dependent exocytosis (GO:0017156) | 2.98585100 |
| 150 | negative regulation of axon extension involved in axon guidance (GO:0048843) | 2.98494151 |
| 151 | positive regulation of gastrulation (GO:2000543) | 2.96353198 |
| 152 | negative regulation of receptor-mediated endocytosis (GO:0048261) | 2.95840179 |
| 153 | cytoskeleton-dependent intracellular transport (GO:0030705) | 2.95651932 |
| 154 | piRNA metabolic process (GO:0034587) | 2.95508230 |
| 155 | inner ear receptor cell differentiation (GO:0060113) | 2.94695907 |
| 156 | cell-cell junction maintenance (GO:0045217) | 2.88900366 |
| 157 | cell junction maintenance (GO:0034331) | 2.84829806 |
| 158 | neuromuscular synaptic transmission (GO:0007274) | 2.83022233 |
| 159 | mitochondrion localization (GO:0051646) | 2.82211422 |
| 160 | N-glycan processing (GO:0006491) | 2.79846246 |
| 161 | retinal ganglion cell axon guidance (GO:0031290) | 2.78266085 |
| 162 | glycosphingolipid biosynthetic process (GO:0006688) | 2.74759179 |
| 163 | axon cargo transport (GO:0008088) | 2.73214844 |
| 164 | microtubule-based transport (GO:0010970) | 2.71583738 |
| 165 | entrainment of circadian clock (GO:0009649) | 2.70397678 |
| 166 | protein localization to cilium (GO:0061512) | 2.70018473 |
| 167 | kynurenine metabolic process (GO:0070189) | 2.69552353 |
| 168 | protein targeting to lysosome (GO:0006622) | 2.68497115 |
| 169 | establishment of protein localization to vacuole (GO:0072666) | 2.68497115 |
| 170 | protein targeting to vacuole (GO:0006623) | 2.68497115 |
| 171 | membrane depolarization (GO:0051899) | 2.68155369 |
| 172 | action potential (GO:0001508) | 2.67848740 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.11975213 |
| 2 | * RARB_27405468_Chip-Seq_BRAIN_Mouse | 4.10954888 |
| 3 | VDR_22108803_ChIP-Seq_LS180_Human | 4.04828863 |
| 4 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 3.28165310 |
| 5 | * SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 3.19798026 |
| 6 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 3.14593038 |
| 7 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 3.10246641 |
| 8 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 3.01092411 |
| 9 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.01088485 |
| 10 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.83993760 |
| 11 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.81605573 |
| 12 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.81605573 |
| 13 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.80340725 |
| 14 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.79416678 |
| 15 | * REST_21632747_ChIP-Seq_MESCs_Mouse | 2.75083737 |
| 16 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.73575557 |
| 17 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.71226809 |
| 18 | * SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.70535867 |
| 19 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.67789932 |
| 20 | * MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.65988509 |
| 21 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.57875825 |
| 22 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.52187737 |
| 23 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.43937826 |
| 24 | * SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.42312160 |
| 25 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.40143206 |
| 26 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.37184115 |
| 27 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.33095689 |
| 28 | * EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.32204321 |
| 29 | * REST_18959480_ChIP-ChIP_MESCs_Mouse | 2.30252496 |
| 30 | * SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.28279127 |
| 31 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.24292149 |
| 32 | RNF2_27304074_Chip-Seq_NSC_Mouse | 2.22062820 |
| 33 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.15427884 |
| 34 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.00628660 |
| 35 | * EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.95244969 |
| 36 | * ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.87755440 |
| 37 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.87304410 |
| 38 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.85767020 |
| 39 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.83346087 |
| 40 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.67819540 |
| 41 | * DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.56374857 |
| 42 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.52213219 |
| 43 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.50741682 |
| 44 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.46715585 |
| 45 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.43295454 |
| 46 | * RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.40087586 |
| 47 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.36725247 |
| 48 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.35707843 |
| 49 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.34558205 |
| 50 | KDM2B_26808549_Chip-Seq_K562_Human | 1.34446038 |
| 51 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.33984433 |
| 52 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.32243693 |
| 53 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.31590308 |
| 54 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.29307188 |
| 55 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.29169481 |
| 56 | * SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.28293883 |
| 57 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.27546932 |
| 58 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.26912142 |
| 59 | * UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.24528823 |
| 60 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.24457109 |
| 61 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.24277100 |
| 62 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.22916617 |
| 63 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.22166735 |
| 64 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.21305706 |
| 65 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.19247837 |
| 66 | * SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.18899115 |
| 67 | * P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.18656248 |
| 68 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.17949704 |
| 69 | AR_19668381_ChIP-Seq_PC3_Human | 1.17933076 |
| 70 | * GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.15092172 |
| 71 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.13717035 |
| 72 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.13023450 |
| 73 | * SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.12587195 |
| 74 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.11400816 |
| 75 | STAT3_23295773_ChIP-Seq_U87_Human | 1.09227648 |
| 76 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.09199225 |
| 77 | * CTCF_27219007_Chip-Seq_Bcells_Human | 1.08164045 |
| 78 | JUN_21703547_ChIP-Seq_K562_Human | 1.07612807 |
| 79 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.04885970 |
| 80 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.03692274 |
| 81 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.03588714 |
| 82 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.03260978 |
| 83 | FUS_26573619_Chip-Seq_HEK293_Human | 1.03122845 |
| 84 | * SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.03062425 |
| 85 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.02083858 |
| 86 | P300_19829295_ChIP-Seq_ESCs_Human | 0.99964978 |
| 87 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 0.99073189 |
| 88 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.98983149 |
| 89 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.98784705 |
| 90 | SETDB1_19884257_ChIP-Seq_MESCs_Mouse | 0.97565304 |
| 91 | EWS_26573619_Chip-Seq_HEK293_Human | 0.97052132 |
| 92 | KLF4_19829295_ChIP-Seq_ESCs_Human | 0.96789222 |
| 93 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 0.96417154 |
| 94 | REST_19997604_ChIP-ChIP_NEURONS_Mouse | 0.95904121 |
| 95 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.95805067 |
| 96 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.94440637 |
| 97 | TCF4_23295773_ChIP-Seq_U87_Human | 0.94063157 |
| 98 | AR_25329375_ChIP-Seq_VCAP_Human | 0.93660077 |
| 99 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 0.93558331 |
| 100 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.93377434 |
| 101 | NCOR_22424771_ChIP-Seq_293T_Human | 0.92998452 |
| 102 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.92883427 |
| 103 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 0.92596491 |
| 104 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.92472995 |
| 105 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.92132475 |
| 106 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 0.91988694 |
| 107 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.91975269 |
| 108 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.91652129 |
| 109 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.91231754 |
| 110 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.90367240 |
| 111 | * FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.90092571 |
| 112 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.89954693 |
| 113 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.89359536 |
| 114 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.89206636 |
| 115 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 0.88911165 |
| 116 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 0.88451796 |
| 117 | * TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.88214657 |
| 118 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.88213198 |
| 119 | * TAF2_19829295_ChIP-Seq_ESCs_Human | 0.87349768 |
| 120 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.86942256 |
| 121 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.86847709 |
| 122 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.85962548 |
| 123 | * SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.85778235 |
| 124 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 0.84842662 |
| 125 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.84807505 |
| 126 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 0.84507500 |
| 127 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.83084223 |
| 128 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 0.82879277 |
| 129 | * TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.82622361 |
| 130 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.82252956 |
| 131 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.82216579 |
| 132 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.81879516 |
| 133 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.80630586 |
| 134 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.80339570 |
| 135 | * BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.79507359 |
| 136 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.79409302 |
| 137 | TP53_16413492_ChIP-PET_HCT116_Human | 0.78623271 |
| 138 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.78480608 |
| 139 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.78418398 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002822_catalepsy | 9.16446225 |
| 2 | MP0004859_abnormal_synaptic_plasticity | 6.12764011 |
| 3 | MP0003880_abnormal_central_pattern | 4.14399352 |
| 4 | MP0003635_abnormal_synaptic_transmissio | 4.07140672 |
| 5 | MP0009745_abnormal_behavioral_response | 3.78998409 |
| 6 | MP0002102_abnormal_ear_morphology | 3.60644593 |
| 7 | MP0003121_genomic_imprinting | 3.54075147 |
| 8 | * MP0002063_abnormal_learning/memory/cond | 3.42390650 |
| 9 | MP0004270_analgesia | 3.20686108 |
| 10 | MP0008877_abnormal_DNA_methylation | 3.18356776 |
| 11 | MP0001529_abnormal_vocalization | 3.04873571 |
| 12 | MP0002064_seizures | 2.98776016 |
| 13 | MP0002572_abnormal_emotion/affect_behav | 2.82612880 |
| 14 | MP0003011_delayed_dark_adaptation | 2.73427995 |
| 15 | MP0009046_muscle_twitch | 2.70635746 |
| 16 | MP0001486_abnormal_startle_reflex | 2.70378243 |
| 17 | MP0001968_abnormal_touch/_nociception | 2.56308694 |
| 18 | MP0005423_abnormal_somatic_nervous | 2.51133289 |
| 19 | MP0002272_abnormal_nervous_system | 2.42772129 |
| 20 | MP0002909_abnormal_adrenal_gland | 2.41475152 |
| 21 | MP0006072_abnormal_retinal_apoptosis | 2.23431626 |
| 22 | MP0005646_abnormal_pituitary_gland | 2.14602877 |
| 23 | MP0003890_abnormal_embryonic-extraembry | 2.11644544 |
| 24 | MP0002734_abnormal_mechanical_nocicepti | 2.11098567 |
| 25 | MP0001501_abnormal_sleep_pattern | 2.03964993 |
| 26 | MP0004924_abnormal_behavior | 2.01685884 |
| 27 | MP0005386_behavior/neurological_phenoty | 2.01685884 |
| 28 | MP0005409_darkened_coat_color | 1.97008691 |
| 29 | MP0001970_abnormal_pain_threshold | 1.84193324 |
| 30 | MP0002733_abnormal_thermal_nociception | 1.80433880 |
| 31 | MP0001188_hyperpigmentation | 1.77544958 |
| 32 | MP0003878_abnormal_ear_physiology | 1.76509794 |
| 33 | MP0005377_hearing/vestibular/ear_phenot | 1.76509794 |
| 34 | MP0002736_abnormal_nociception_after | 1.70400895 |
| 35 | MP0002557_abnormal_social/conspecific_i | 1.70320068 |
| 36 | MP0001984_abnormal_olfaction | 1.69610652 |
| 37 | MP0001440_abnormal_grooming_behavior | 1.65003654 |
| 38 | MP0004811_abnormal_neuron_physiology | 1.62479181 |
| 39 | MP0008569_lethality_at_weaning | 1.57581637 |
| 40 | MP0003123_paternal_imprinting | 1.56672938 |
| 41 | MP0005253_abnormal_eye_physiology | 1.52059443 |
| 42 | MP0002332_abnormal_exercise_endurance | 1.51894523 |
| 43 | MP0009780_abnormal_chondrocyte_physiolo | 1.48599184 |
| 44 | MP0001986_abnormal_taste_sensitivity | 1.48246317 |
| 45 | MP0001905_abnormal_dopamine_level | 1.46278039 |
| 46 | MP0002067_abnormal_sensory_capabilities | 1.45886646 |
| 47 | MP0003075_altered_response_to | 1.41189679 |
| 48 | MP0008872_abnormal_physiological_respon | 1.37088033 |
| 49 | MP0008874_decreased_physiological_sensi | 1.35778503 |
| 50 | MP0005167_abnormal_blood-brain_barrier | 1.31359685 |
| 51 | MP0003329_amyloid_beta_deposits | 1.31168239 |
| 52 | MP0005083_abnormal_biliary_tract | 1.31013512 |
| 53 | MP0003879_abnormal_hair_cell | 1.30991664 |
| 54 | MP0003633_abnormal_nervous_system | 1.29131601 |
| 55 | MP0002066_abnormal_motor_capabilities/c | 1.27966609 |
| 56 | MP0002735_abnormal_chemical_nociception | 1.27717728 |
| 57 | MP0000013_abnormal_adipose_tissue | 1.27535386 |
| 58 | MP0004885_abnormal_endolymph | 1.23388082 |
| 59 | MP0001177_atelectasis | 1.22825837 |
| 60 | MP0002184_abnormal_innervation | 1.22784382 |
| 61 | MP0000955_abnormal_spinal_cord | 1.19590295 |
| 62 | MP0010234_abnormal_vibrissa_follicle | 1.10868527 |
| 63 | MP0002882_abnormal_neuron_morphology | 1.08417113 |
| 64 | MP0000778_abnormal_nervous_system | 1.06649435 |
| 65 | MP0003283_abnormal_digestive_organ | 1.03825908 |
| 66 | MP0008961_abnormal_basal_metabolism | 1.02255493 |
| 67 | MP0004085_abnormal_heartbeat | 1.01899126 |
| 68 | MP0003631_nervous_system_phenotype | 1.00159277 |
| 69 | MP0001502_abnormal_circadian_rhythm | 0.98838300 |
| 70 | MP0004142_abnormal_muscle_tone | 0.97950899 |
| 71 | MP0002069_abnormal_eating/drinking_beha | 0.97055554 |
| 72 | MP0002090_abnormal_vision | 0.96167941 |
| 73 | MP0004858_abnormal_nervous_system | 0.94427233 |
| 74 | MP0003690_abnormal_glial_cell | 0.93560433 |
| 75 | MP0005535_abnormal_body_temperature | 0.92873614 |
| 76 | MP0004264_abnormal_extraembryonic_tissu | 0.91241977 |
| 77 | MP0004133_heterotaxia | 0.89482093 |
| 78 | MP0008789_abnormal_olfactory_epithelium | 0.88127765 |
| 79 | MP0000751_myopathy | 0.87996002 |
| 80 | MP0002876_abnormal_thyroid_physiology | 0.85751931 |
| 81 | MP0003787_abnormal_imprinting | 0.84252866 |
| 82 | * MP0002152_abnormal_brain_morphology | 0.83752294 |
| 83 | MP0001764_abnormal_homeostasis | 0.82713976 |
| 84 | MP0000920_abnormal_myelination | 0.80249886 |
| 85 | MP0005195_abnormal_posterior_eye | 0.80235364 |
| 86 | MP0005623_abnormal_meninges_morphology | 0.80200817 |
| 87 | MP0003861_abnormal_nervous_system | 0.79529439 |
| 88 | MP0005645_abnormal_hypothalamus_physiol | 0.78574942 |
| 89 | MP0006276_abnormal_autonomic_nervous | 0.77499959 |
| 90 | MP0005499_abnormal_olfactory_system | 0.75761458 |
| 91 | MP0005394_taste/olfaction_phenotype | 0.75761458 |
| 92 | MP0002160_abnormal_reproductive_system | 0.73288472 |
| 93 | MP0002229_neurodegeneration | 0.71379902 |
| 94 | MP0004130_abnormal_muscle_cell | 0.70904530 |
| 95 | MP0003137_abnormal_impulse_conducting | 0.69864209 |
| 96 | MP0000631_abnormal_neuroendocrine_gland | 0.68841330 |
| 97 | MP0005391_vision/eye_phenotype | 0.67803787 |
| 98 | MP0003122_maternal_imprinting | 0.66775111 |
| 99 | MP0003634_abnormal_glial_cell | 0.64183658 |
| 100 | MP0002928_abnormal_bile_duct | 0.62678707 |
| 101 | MP0005166_decreased_susceptibility_to | 0.60567030 |
| 102 | MP0002254_reproductive_system_inflammat | 0.59422926 |
| 103 | MP0003195_calcinosis | 0.59399757 |
| 104 | MP0001664_abnormal_digestion | 0.59226173 |
| 105 | MP0000604_amyloidosis | 0.58515031 |
| 106 | MP0000026_abnormal_inner_ear | 0.57586314 |
| 107 | MP0008995_early_reproductive_senescence | 0.56789974 |
| 108 | MP0000569_abnormal_digit_pigmentation | 0.55415989 |
| 109 | MP0003938_abnormal_ear_development | 0.55320402 |
| 110 | MP0005389_reproductive_system_phenotype | 0.55136404 |
| 111 | MP0003632_abnormal_nervous_system | 0.53439494 |
| 112 | MP0005551_abnormal_eye_electrophysiolog | 0.52233100 |
| 113 | MP0001293_anophthalmia | 0.51535641 |
| 114 | MP0000538_abnormal_urinary_bladder | 0.50573178 |
| 115 | MP0002638_abnormal_pupillary_reflex | 0.50526421 |
| 116 | MP0004043_abnormal_pH_regulation | 0.50099079 |
| 117 | MP0001943_abnormal_respiration | 0.47636797 |
| 118 | MP0004742_abnormal_vestibular_system | 0.47430431 |
| 119 | MP0003956_abnormal_body_size | 0.44834315 |
| 120 | MP0000003_abnormal_adipose_tissue | 0.42414091 |
| 121 | MP0002752_abnormal_somatic_nervous | 0.41715655 |
| 122 | MP0001963_abnormal_hearing_physiology | 0.40223277 |
| 123 | MP0000230_abnormal_systemic_arterial | 0.38769076 |
| 124 | MP0010386_abnormal_urinary_bladder | 0.37930675 |
| 125 | MP0001485_abnormal_pinna_reflex | 0.37618808 |
| 126 | MP0003303_peritoneal_inflammation | 0.37308716 |
| 127 | MP0010769_abnormal_survival | 0.36938728 |
| 128 | MP0004036_abnormal_muscle_relaxation | 0.36896812 |
| 129 | MP0005620_abnormal_muscle_contractility | 0.36453972 |
| 130 | MP0004145_abnormal_muscle_electrophysio | 0.35903092 |
| 131 | MP0002082_postnatal_lethality | 0.35766836 |
| 132 | MP0010770_preweaning_lethality | 0.35766836 |
| 133 | MP0004233_abnormal_muscle_weight | 0.34914254 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Myokymia (HP:0002411) | 9.67063885 |
| 2 | Focal motor seizures (HP:0011153) | 7.72701401 |
| 3 | Pendular nystagmus (HP:0012043) | 5.81967477 |
| 4 | Focal seizures (HP:0007359) | 5.66358700 |
| 5 | Polyphagia (HP:0002591) | 4.94599298 |
| 6 | Chronic hepatic failure (HP:0100626) | 4.78285519 |
| 7 | Annular pancreas (HP:0001734) | 4.77641849 |
| 8 | Resting tremor (HP:0002322) | 4.76125141 |
| 9 | Torticollis (HP:0000473) | 4.55495804 |
| 10 | Visual hallucinations (HP:0002367) | 4.54892153 |
| 11 | Abnormality of the labia minora (HP:0012880) | 4.48786142 |
| 12 | Cortical dysplasia (HP:0002539) | 4.42976789 |
| 13 | Poor eye contact (HP:0000817) | 4.27092333 |
| 14 | Anxiety (HP:0000739) | 4.09231998 |
| 15 | Focal dystonia (HP:0004373) | 3.95269271 |
| 16 | Failure to thrive in infancy (HP:0001531) | 3.94036907 |
| 17 | Craniofacial dystonia (HP:0012179) | 3.89019932 |
| 18 | Action tremor (HP:0002345) | 3.86593123 |
| 19 | Abnormal social behavior (HP:0012433) | 3.83010251 |
| 20 | Impaired social interactions (HP:0000735) | 3.83010251 |
| 21 | Ankle clonus (HP:0011448) | 3.77038688 |
| 22 | Depression (HP:0000716) | 3.74142937 |
| 23 | Abnormal pancreas size (HP:0012094) | 3.72584891 |
| 24 | Impaired vibration sensation in the lower limbs (HP:0002166) | 3.68168900 |
| 25 | Esotropia (HP:0000565) | 3.62035473 |
| 26 | Broad-based gait (HP:0002136) | 3.60720722 |
| 27 | Epileptic encephalopathy (HP:0200134) | 3.56001562 |
| 28 | Generalized tonic-clonic seizures (HP:0002069) | 3.51127327 |
| 29 | Buphthalmos (HP:0000557) | 3.50289166 |
| 30 | Ankyloglossia (HP:0010296) | 3.46833369 |
| 31 | Febrile seizures (HP:0002373) | 3.40636378 |
| 32 | Dysdiadochokinesis (HP:0002075) | 3.38137201 |
| 33 | Absence seizures (HP:0002121) | 3.34066098 |
| 34 | Abnormal hair whorl (HP:0010721) | 3.30008719 |
| 35 | Urinary bladder sphincter dysfunction (HP:0002839) | 3.19565042 |
| 36 | Stereotypic behavior (HP:0000733) | 3.17301056 |
| 37 | Oligomenorrhea (HP:0000876) | 3.15074519 |
| 38 | Abnormality of midbrain morphology (HP:0002418) | 3.14233364 |
| 39 | Molar tooth sign on MRI (HP:0002419) | 3.14233364 |
| 40 | Dialeptic seizures (HP:0011146) | 3.11002622 |
| 41 | Pointed chin (HP:0000307) | 3.09178468 |
| 42 | Papilledema (HP:0001085) | 3.05800486 |
| 43 | Lower limb amyotrophy (HP:0007210) | 3.04141423 |
| 44 | Hemorrhage of the eye (HP:0011885) | 3.03964674 |
| 45 | Gaze-evoked nystagmus (HP:0000640) | 3.03781699 |
| 46 | Scanning speech (HP:0002168) | 3.02736969 |
| 47 | Hypoplasia of the brainstem (HP:0002365) | 3.01660012 |
| 48 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 3.01660012 |
| 49 | Limb dystonia (HP:0002451) | 3.01041629 |
| 50 | Spastic tetraplegia (HP:0002510) | 2.98664278 |
| 51 | Sleep apnea (HP:0010535) | 2.98025161 |
| 52 | Abnormal eating behavior (HP:0100738) | 2.96428881 |
| 53 | Prolonged QT interval (HP:0001657) | 2.95891968 |
| 54 | Urinary urgency (HP:0000012) | 2.94475729 |
| 55 | Abnormality of the corticospinal tract (HP:0002492) | 2.94315474 |
| 56 | Dysmetria (HP:0001310) | 2.94090743 |
| 57 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.93358033 |
| 58 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.93358033 |
| 59 | Atonic seizures (HP:0010819) | 2.92582579 |
| 60 | Postural instability (HP:0002172) | 2.91141102 |
| 61 | Agitation (HP:0000713) | 2.80579178 |
| 62 | Truncal ataxia (HP:0002078) | 2.79824452 |
| 63 | Dysmetric saccades (HP:0000641) | 2.76238681 |
| 64 | Supranuclear gaze palsy (HP:0000605) | 2.75164363 |
| 65 | Polygenic inheritance (HP:0010982) | 2.74164134 |
| 66 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.71574767 |
| 67 | Abnormal EKG (HP:0003115) | 2.70404383 |
| 68 | Progressive cerebellar ataxia (HP:0002073) | 2.70262927 |
| 69 | Megalencephaly (HP:0001355) | 2.69268933 |
| 70 | Retinal dysplasia (HP:0007973) | 2.65352119 |
| 71 | Atrioventricular block (HP:0001678) | 2.63040993 |
| 72 | Abnormality of oral frenula (HP:0000190) | 2.62013341 |
| 73 | Abolished electroretinogram (ERG) (HP:0000550) | 2.60949713 |
| 74 | Spastic gait (HP:0002064) | 2.59192979 |
| 75 | Amblyopia (HP:0000646) | 2.58429457 |
| 76 | Specific learning disability (HP:0001328) | 2.58071190 |
| 77 | Hypoalbuminemia (HP:0003073) | 2.56883088 |
| 78 | Abnormal albumin level (HP:0012116) | 2.56883088 |
| 79 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.55432474 |
| 80 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.55432474 |
| 81 | Distal lower limb amyotrophy (HP:0008944) | 2.54876735 |
| 82 | Pachygyria (HP:0001302) | 2.53709006 |
| 83 | Intention tremor (HP:0002080) | 2.53140408 |
| 84 | Hip dysplasia (HP:0001385) | 2.52290538 |
| 85 | Impaired smooth pursuit (HP:0007772) | 2.51359003 |
| 86 | Mutism (HP:0002300) | 2.48706148 |
| 87 | Impaired vibratory sensation (HP:0002495) | 2.48644110 |
| 88 | Bradykinesia (HP:0002067) | 2.47546038 |
| 89 | True hermaphroditism (HP:0010459) | 2.43582921 |
| 90 | 3-Methylglutaconic aciduria (HP:0003535) | 2.40247558 |
| 91 | Limb hypertonia (HP:0002509) | 2.30831376 |
| 92 | Polymicrogyria (HP:0002126) | 2.29925418 |
| 93 | Hyperventilation (HP:0002883) | 2.27383525 |
| 94 | Truncus arteriosus (HP:0001660) | 2.27323380 |
| 95 | Progressive inability to walk (HP:0002505) | 2.26887606 |
| 96 | Tubulointerstitial fibrosis (HP:0005576) | 2.26653574 |
| 97 | Decreased muscle mass (HP:0003199) | 2.25306249 |
| 98 | Lissencephaly (HP:0001339) | 2.24975573 |
| 99 | Poor suck (HP:0002033) | 2.23852018 |
| 100 | Status epilepticus (HP:0002133) | 2.23027643 |
| 101 | Labial hypoplasia (HP:0000066) | 2.22670504 |
| 102 | Neurofibrillary tangles (HP:0002185) | 2.21255274 |
| 103 | Clonus (HP:0002169) | 2.21134991 |
| 104 | Cerebral inclusion bodies (HP:0100314) | 2.20964341 |
| 105 | Lower limb asymmetry (HP:0100559) | 2.20396597 |
| 106 | Abnormality of the lower motor neuron (HP:0002366) | 2.20164590 |
| 107 | Incomplete penetrance (HP:0003829) | 2.19074824 |
| 108 | Heart block (HP:0012722) | 2.18717230 |
| 109 | Pancreatic fibrosis (HP:0100732) | 2.14575810 |
| 110 | Ventricular fibrillation (HP:0001663) | 2.14239935 |
| 111 | Abnormality of the anterior chamber (HP:0000593) | 2.13972493 |
| 112 | Lower limb muscle weakness (HP:0007340) | 2.13945936 |
| 113 | Microretrognathia (HP:0000308) | 2.12841972 |
| 114 | Upper limb amyotrophy (HP:0009129) | 2.07903913 |
| 115 | Distal upper limb amyotrophy (HP:0007149) | 2.07903913 |
| 116 | Gait imbalance (HP:0002141) | 2.07123356 |
| 117 | Congenital glaucoma (HP:0001087) | 2.05557310 |
| 118 | Morphological abnormality of the pyramidal tract (HP:0002062) | 2.05469111 |
| 119 | Axonal loss (HP:0003447) | 2.05365628 |
| 120 | Termporal pattern (HP:0011008) | 2.05040251 |
| 121 | Insidious onset (HP:0003587) | 2.05040251 |
| 122 | Bowel incontinence (HP:0002607) | 2.04978488 |
| 123 | Abnormality of ocular smooth pursuit (HP:0000617) | 2.04703478 |
| 124 | Hemiparesis (HP:0001269) | 2.03666514 |
| 125 | Pancreatic cysts (HP:0001737) | 2.01254700 |
| 126 | Cortical visual impairment (HP:0100704) | 2.01004653 |
| 127 | Neuronal loss in central nervous system (HP:0002529) | 2.00940570 |
| 128 | Hypoplastic female external genitalia (HP:0012815) | 1.99342796 |
| 129 | Obstructive sleep apnea (HP:0002870) | 1.98541320 |
| 130 | Abnormal atrioventricular conduction (HP:0005150) | 1.97418252 |
| 131 | Hypomagnesemia (HP:0002917) | 1.97091044 |
| 132 | Hypogonadotrophic hypogonadism (HP:0000044) | 1.96305995 |
| 133 | Hemiplegia (HP:0002301) | 1.95053729 |
| 134 | Epileptiform EEG discharges (HP:0011182) | 1.93411286 |
| 135 | Drooling (HP:0002307) | 1.93261586 |
| 136 | Excessive salivation (HP:0003781) | 1.93261586 |
| 137 | Abnormal ciliary motility (HP:0012262) | 1.92934728 |
| 138 | Palpebral edema (HP:0100540) | 1.92524935 |
| 139 | Insomnia (HP:0100785) | 1.92300569 |
| 140 | EEG with generalized epileptiform discharges (HP:0011198) | 1.90917532 |
| 141 | Long foot (HP:0001833) | 1.89874440 |
| 142 | Hypsarrhythmia (HP:0002521) | 1.88853194 |
| 143 | Vaginal atresia (HP:0000148) | 1.88501933 |
| 144 | Spinal canal stenosis (HP:0003416) | 1.86590868 |
| 145 | Abnormality of saccadic eye movements (HP:0000570) | 1.85250464 |
| 146 | Abnormal large intestine physiology (HP:0012700) | 1.84135930 |
| 147 | Rigidity (HP:0002063) | 1.83404783 |
| 148 | Neoplasm of the peripheral nervous system (HP:0100007) | 1.82813006 |
| 149 | Abnormality of the labia (HP:0000058) | 1.82570399 |
| 150 | Generalized hypopigmentation (HP:0007513) | 1.82064643 |
| 151 | Abnormality of the periventricular white matter (HP:0002518) | 1.81711873 |
| 152 | Onion bulb formation (HP:0003383) | 1.81446749 |
| 153 | Genital tract atresia (HP:0001827) | 1.81218488 |
| 154 | Fetal akinesia sequence (HP:0001989) | 1.80663217 |
| 155 | Restlessness (HP:0000711) | 1.80058759 |
| 156 | Dysphonia (HP:0001618) | 1.79551462 |
| 157 | Pheochromocytoma (HP:0002666) | 1.77765050 |
| 158 | Generalized hypotonia (HP:0001290) | 1.77718436 |
| 159 | Abnormal tarsal ossification (HP:0008369) | 1.77150309 |
| 160 | Hypoplasia of the corpus callosum (HP:0002079) | 1.75224290 |
| 161 | Bilateral microphthalmos (HP:0007633) | 1.74471382 |
| 162 | Narrow forehead (HP:0000341) | 1.74129685 |
| 163 | Wrist flexion contracture (HP:0001239) | 1.73764849 |
| 164 | Growth hormone deficiency (HP:0000824) | 1.72373420 |
| 165 | Hypoventilation (HP:0002791) | 1.71316600 |
| 166 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.71285597 |
| 167 | Narrow nasal bridge (HP:0000446) | 1.70398256 |
| 168 | Protruding tongue (HP:0010808) | 1.69658965 |
| 169 | Tubulointerstitial abnormality (HP:0001969) | 1.69419676 |
| 170 | Postaxial foot polydactyly (HP:0001830) | 1.69372752 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EPHA4 | 8.11455238 |
| 2 | EPHA3 | 4.76557438 |
| 3 | NTRK3 | 3.97370185 |
| 4 | MAP3K9 | 3.62650421 |
| 5 | SIK3 | 3.02281794 |
| 6 | KSR2 | 2.93341572 |
| 7 | WNK3 | 2.88648563 |
| 8 | DAPK2 | 2.87820573 |
| 9 | RIPK4 | 2.51017075 |
| 10 | PRKD3 | 2.47423870 |
| 11 | EPHB1 | 2.40780514 |
| 12 | CAMKK1 | 2.24729115 |
| 13 | MAP3K11 | 2.20944346 |
| 14 | MINK1 | 2.16341032 |
| 15 | NTRK1 | 2.13604490 |
| 16 | ARAF | 2.09284231 |
| 17 | MAP3K13 | 2.02163642 |
| 18 | FES | 1.96475162 |
| 19 | NTRK2 | 1.93851668 |
| 20 | BCR | 1.93129412 |
| 21 | DYRK2 | 1.90719825 |
| 22 | MARK1 | 1.89625099 |
| 23 | MAP3K4 | 1.86392869 |
| 24 | KSR1 | 1.84105429 |
| 25 | EIF2AK3 | 1.70157862 |
| 26 | TAOK1 | 1.69329419 |
| 27 | CDK5 | 1.62278199 |
| 28 | FRK | 1.58173946 |
| 29 | PAK6 | 1.57394216 |
| 30 | STK16 | 1.57194271 |
| 31 | DAPK1 | 1.56374146 |
| 32 | MAP3K2 | 1.55772023 |
| 33 | CAMKK2 | 1.53852838 |
| 34 | WNK4 | 1.53498917 |
| 35 | TNIK | 1.47239179 |
| 36 | TYRO3 | 1.44006850 |
| 37 | SIK2 | 1.43931305 |
| 38 | NEK2 | 1.42065064 |
| 39 | MAP2K7 | 1.35905024 |
| 40 | RAF1 | 1.28574246 |
| 41 | DYRK3 | 1.25568164 |
| 42 | MAP3K5 | 1.19160254 |
| 43 | NUAK1 | 1.14187695 |
| 44 | STK39 | 1.13544232 |
| 45 | MAP2K4 | 1.08534567 |
| 46 | MAP4K2 | 1.04773256 |
| 47 | PRPF4B | 1.03411878 |
| 48 | SGK494 | 0.98163444 |
| 49 | SGK223 | 0.98163444 |
| 50 | PRKCH | 0.96404479 |
| 51 | BMPR2 | 0.96364735 |
| 52 | UHMK1 | 0.95630409 |
| 53 | PRKCQ | 0.93009185 |
| 54 | CDK18 | 0.91433885 |
| 55 | CDK15 | 0.90492402 |
| 56 | PINK1 | 0.89696001 |
| 57 | TRIM28 | 0.88453402 |
| 58 | CDK14 | 0.87576136 |
| 59 | STK38 | 0.86582550 |
| 60 | FER | 0.84688500 |
| 61 | PRKCG | 0.84587000 |
| 62 | GRK5 | 0.83921421 |
| 63 | MARK2 | 0.82654651 |
| 64 | CAMK2B | 0.82057991 |
| 65 | MARK3 | 0.81352678 |
| 66 | RET | 0.80913934 |
| 67 | STK11 | 0.80693960 |
| 68 | SGK1 | 0.80474015 |
| 69 | CSNK1G3 | 0.80401832 |
| 70 | SGK2 | 0.79829885 |
| 71 | PDPK1 | 0.79422167 |
| 72 | NEK1 | 0.79387527 |
| 73 | CDK11A | 0.79143701 |
| 74 | MAPK13 | 0.78941646 |
| 75 | CAMK2A | 0.78509147 |
| 76 | SIK1 | 0.77669885 |
| 77 | RPS6KA4 | 0.76257344 |
| 78 | MAP3K1 | 0.75839307 |
| 79 | ALK | 0.75719147 |
| 80 | OXSR1 | 0.74991841 |
| 81 | SGK3 | 0.74537110 |
| 82 | CAMK1D | 0.73343914 |
| 83 | PDK1 | 0.72956443 |
| 84 | TNK2 | 0.68322282 |
| 85 | PTK2B | 0.68030980 |
| 86 | CAMK1 | 0.67867331 |
| 87 | PIK3CA | 0.66236832 |
| 88 | MAP3K12 | 0.64289467 |
| 89 | LIMK1 | 0.63916208 |
| 90 | MAP2K1 | 0.62335997 |
| 91 | CSNK1A1L | 0.61125701 |
| 92 | PLK2 | 0.60339733 |
| 93 | CSNK1G1 | 0.59834886 |
| 94 | DAPK3 | 0.58841233 |
| 95 | NEK6 | 0.57398976 |
| 96 | GRK1 | 0.56938457 |
| 97 | MOS | 0.55288790 |
| 98 | FYN | 0.54623802 |
| 99 | IRAK1 | 0.53967968 |
| 100 | PRKCZ | 0.53541291 |
| 101 | RPS6KA5 | 0.53270894 |
| 102 | LMTK2 | 0.53072252 |
| 103 | RPS6KA3 | 0.52793922 |
| 104 | BRSK1 | 0.50493450 |
| 105 | RIPK1 | 0.50154477 |
| 106 | PRKD2 | 0.48640764 |
| 107 | PHKG1 | 0.45891454 |
| 108 | PHKG2 | 0.45891454 |
| 109 | CAMK4 | 0.44446845 |
| 110 | MAPK10 | 0.44196667 |
| 111 | BRAF | 0.43885412 |
| 112 | FGFR4 | 0.42737063 |
| 113 | TRIB3 | 0.40974710 |
| 114 | DMPK | 0.40125327 |
| 115 | FGFR2 | 0.39754741 |
| 116 | SCYL2 | 0.39256870 |
| 117 | CAMK2G | 0.38951185 |
| 118 | CDK19 | 0.38655439 |
| 119 | CAMK2D | 0.38403548 |
| 120 | RPS6KB1 | 0.37858767 |
| 121 | INSRR | 0.37743568 |
| 122 | PRKCE | 0.35850415 |
| 123 | CSNK1G2 | 0.34802206 |
| 124 | CASK | 0.34752260 |
| 125 | FGR | 0.33372401 |
| 126 | PRKCB | 0.33347742 |
| 127 | DYRK1A | 0.32282323 |
| 128 | TLK1 | 0.32146009 |
| 129 | IKBKE | 0.31672868 |
| 130 | PRKAA1 | 0.31566315 |
| 131 | RPS6KA2 | 0.31421493 |
| 132 | PAK3 | 0.31175460 |
| 133 | PNCK | 0.30900398 |
| 134 | PRKACA | 0.30794192 |
| 135 | PRKACG | 0.30724659 |
| 136 | DYRK1B | 0.28521300 |
| 137 | MAP3K6 | 0.28520009 |
| 138 | CSNK1A1 | 0.27578383 |
| 139 | WNK1 | 0.27199576 |
| 140 | MAPK8 | 0.25975257 |
| 141 | PRKCA | 0.25664088 |
| 142 | PKN1 | 0.24848398 |
| 143 | TIE1 | 0.24602453 |
| 144 | MAPK15 | 0.24133355 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Olfactory transduction_Homo sapiens_hsa04740 | 3.83879637 |
| 2 | Morphine addiction_Homo sapiens_hsa05032 | 3.01202972 |
| 3 | Nicotine addiction_Homo sapiens_hsa05033 | 2.96531264 |
| 4 | Cocaine addiction_Homo sapiens_hsa05030 | 2.88171801 |
| 5 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.85825094 |
| 6 | GABAergic synapse_Homo sapiens_hsa04727 | 2.84799516 |
| 7 | Circadian entrainment_Homo sapiens_hsa04713 | 2.75717872 |
| 8 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.71310823 |
| 9 | Long-term potentiation_Homo sapiens_hsa04720 | 2.63146311 |
| 10 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.49876834 |
| 11 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.47740617 |
| 12 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.41773838 |
| 13 | Cholinergic synapse_Homo sapiens_hsa04725 | 2.28786410 |
| 14 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 2.06151052 |
| 15 | Renin secretion_Homo sapiens_hsa04924 | 2.05194522 |
| 16 | Salivary secretion_Homo sapiens_hsa04970 | 2.03071319 |
| 17 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.91917396 |
| 18 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.85609906 |
| 19 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.80327989 |
| 20 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.77033586 |
| 21 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.74243286 |
| 22 | Insulin secretion_Homo sapiens_hsa04911 | 1.70478819 |
| 23 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.69016416 |
| 24 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.67609829 |
| 25 | Gap junction_Homo sapiens_hsa04540 | 1.65546709 |
| 26 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.64787253 |
| 27 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.64011489 |
| 28 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.61887004 |
| 29 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.58303694 |
| 30 | Long-term depression_Homo sapiens_hsa04730 | 1.55553227 |
| 31 | Taste transduction_Homo sapiens_hsa04742 | 1.53948669 |
| 32 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.44125154 |
| 33 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.40565663 |
| 34 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.38510739 |
| 35 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.37597892 |
| 36 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.32389360 |
| 37 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.29763996 |
| 38 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.26087940 |
| 39 | Glioma_Homo sapiens_hsa05214 | 1.16854587 |
| 40 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.12808515 |
| 41 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.11679118 |
| 42 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.08533532 |
| 43 | Huntingtons disease_Homo sapiens_hsa05016 | 1.07765917 |
| 44 | ABC transporters_Homo sapiens_hsa02010 | 1.07451824 |
| 45 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.06721550 |
| 46 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.06698302 |
| 47 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.05491816 |
| 48 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.02992642 |
| 49 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.02901923 |
| 50 | Alcoholism_Homo sapiens_hsa05034 | 1.00963273 |
| 51 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.99289988 |
| 52 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.99064570 |
| 53 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.98344966 |
| 54 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.97447025 |
| 55 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.96979397 |
| 56 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.95511361 |
| 57 | Melanogenesis_Homo sapiens_hsa04916 | 0.94595199 |
| 58 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.93610133 |
| 59 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.92834928 |
| 60 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.92716052 |
| 61 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.90977792 |
| 62 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.89483014 |
| 63 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.87845563 |
| 64 | Phototransduction_Homo sapiens_hsa04744 | 0.87593602 |
| 65 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.87209419 |
| 66 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.85993809 |
| 67 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.85502481 |
| 68 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.84965406 |
| 69 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.84668125 |
| 70 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.83498466 |
| 71 | Axon guidance_Homo sapiens_hsa04360 | 0.82170248 |
| 72 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.81685367 |
| 73 | Alzheimers disease_Homo sapiens_hsa05010 | 0.81003191 |
| 74 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.80917510 |
| 75 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.79870757 |
| 76 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.79231636 |
| 77 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.77207965 |
| 78 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.73404905 |
| 79 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.71579704 |
| 80 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.71475451 |
| 81 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.69931706 |
| 82 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.69795615 |
| 83 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.67675683 |
| 84 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.66029723 |
| 85 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.65386870 |
| 86 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.65361838 |
| 87 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.64143132 |
| 88 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.63341888 |
| 89 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.63075497 |
| 90 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.61544126 |
| 91 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.57644941 |
| 92 | Prion diseases_Homo sapiens_hsa05020 | 0.55934561 |
| 93 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.55620059 |
| 94 | Bile secretion_Homo sapiens_hsa04976 | 0.55391789 |
| 95 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.55325729 |
| 96 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.53378162 |
| 97 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.52835330 |
| 98 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.51387809 |
| 99 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.51141292 |
| 100 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.50855596 |
| 101 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.48850430 |
| 102 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.48837847 |
| 103 | Retinol metabolism_Homo sapiens_hsa00830 | 0.48809222 |
| 104 | Phagosome_Homo sapiens_hsa04145 | 0.48432619 |
| 105 | Histidine metabolism_Homo sapiens_hsa00340 | 0.48147332 |
| 106 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.46071174 |
| 107 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.45756683 |
| 108 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.45677580 |
| 109 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.44684155 |
| 110 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.43896083 |
| 111 | Endometrial cancer_Homo sapiens_hsa05213 | 0.43631061 |
| 112 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.42826226 |
| 113 | Thyroid cancer_Homo sapiens_hsa05216 | 0.42513622 |
| 114 | Endocytosis_Homo sapiens_hsa04144 | 0.41395547 |
| 115 | Platelet activation_Homo sapiens_hsa04611 | 0.41365220 |
| 116 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.40869782 |
| 117 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.40793803 |
| 118 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.39415042 |
| 119 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.38949164 |
| 120 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.38679977 |
| 121 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.38144767 |
| 122 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.37321181 |
| 123 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.36802378 |
| 124 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.36566279 |
| 125 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.34977402 |
| 126 | Circadian rhythm_Homo sapiens_hsa04710 | 0.34762299 |
| 127 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.34428608 |
| 128 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.33296266 |
| 129 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.32869332 |
| 130 | Parkinsons disease_Homo sapiens_hsa05012 | 0.32277899 |
| 131 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.31377022 |
| 132 | Salmonella infection_Homo sapiens_hsa05132 | 0.30949876 |
| 133 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.30947807 |
| 134 | Tight junction_Homo sapiens_hsa04530 | 0.29912506 |
| 135 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.29454614 |
| 136 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.27567996 |
| 137 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.27556093 |
| 138 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.26506468 |
| 139 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.25036190 |
| 140 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.24559845 |

