GPR62

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1fatty acid elongation (GO:0030497)6.96773239
2myelination (GO:0042552)6.65766829
3ensheathment of neurons (GO:0007272)6.64080010
4axon ensheathment (GO:0008366)6.64080010
5dopamine biosynthetic process (GO:0042416)6.27874003
6long-chain fatty acid biosynthetic process (GO:0042759)5.55971462
7postsynaptic membrane organization (GO:0001941)5.46398849
8glutamate secretion (GO:0014047)5.23910215
9negative regulation of neurotransmitter secretion (GO:0046929)5.18331321
10myelin maintenance (GO:0043217)4.91115537
11negative regulation of neurotransmitter transport (GO:0051589)4.73795899
12negative regulation of synaptic transmission, GABAergic (GO:0032229)4.59712147
13membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.55241719
14synaptic vesicle exocytosis (GO:0016079)4.47486790
15protein localization to synapse (GO:0035418)4.46015017
16oligodendrocyte differentiation (GO:0048709)4.43476991
17positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.33635826
18presynaptic membrane organization (GO:0097090)4.30106770
19glycerophospholipid catabolic process (GO:0046475)4.17729406
20establishment of mitochondrion localization (GO:0051654)4.16027252
21auditory behavior (GO:0031223)4.14423592
22synaptic vesicle docking involved in exocytosis (GO:0016081)4.12674304
23eye photoreceptor cell differentiation (GO:0001754)4.11634201
24photoreceptor cell differentiation (GO:0046530)4.11634201
25presynaptic membrane assembly (GO:0097105)4.09790699
26synaptic vesicle maturation (GO:0016188)4.08154204
27creatine metabolic process (GO:0006600)4.07934846
28neurotransmitter secretion (GO:0007269)4.05230509
29prepulse inhibition (GO:0060134)3.99975123
30neuron cell-cell adhesion (GO:0007158)3.99398164
31astrocyte development (GO:0014002)3.99295830
32vocalization behavior (GO:0071625)3.99066693
33L-amino acid import (GO:0043092)3.95414227
34ionotropic glutamate receptor signaling pathway (GO:0035235)3.94441605
35negative regulation of protein localization to cell surface (GO:2000009)3.92147807
36regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.89786262
37regulation of collateral sprouting (GO:0048670)3.88902450
38peptidyl-tyrosine autophosphorylation (GO:0038083)3.88051021
39positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.88036141
40cellular potassium ion homeostasis (GO:0030007)3.86767443
41asymmetric protein localization (GO:0008105)3.86424597
42apical protein localization (GO:0045176)3.85215140
43dopamine transport (GO:0015872)3.84178913
44behavioral response to nicotine (GO:0035095)3.82619586
45response to auditory stimulus (GO:0010996)3.78934158
46regulation of synapse structural plasticity (GO:0051823)3.76209043
47catechol-containing compound biosynthetic process (GO:0009713)3.74199959
48catecholamine biosynthetic process (GO:0042423)3.74199959
49negative regulation of peptidyl-threonine phosphorylation (GO:0010801)3.72323377
50substantia nigra development (GO:0021762)3.68229698
51positive regulation of oligodendrocyte differentiation (GO:0048714)3.67795355
52response to methylmercury (GO:0051597)3.67178216
53neurotransmitter transport (GO:0006836)3.64079849
54regulation of short-term neuronal synaptic plasticity (GO:0048172)3.62880035
55response to insecticide (GO:0017085)3.61996757
56neurotransmitter-gated ion channel clustering (GO:0072578)3.61179363
57potassium ion import (GO:0010107)3.60779532
58import into cell (GO:0098657)3.60348743
59regulation of neuronal synaptic plasticity (GO:0048168)3.60146867
60adult walking behavior (GO:0007628)3.56071785
61regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.54559599
62regulation of synaptic vesicle exocytosis (GO:2000300)3.54277746
63regulation of neurotransmitter levels (GO:0001505)3.53711426
64regulation of synaptic vesicle transport (GO:1902803)3.50280826
65cholesterol biosynthetic process (GO:0006695)3.48162901
66cerebral cortex radially oriented cell migration (GO:0021799)3.48125669
67transmission of nerve impulse (GO:0019226)3.47990426
68gamma-aminobutyric acid transport (GO:0015812)3.46879508
69sodium ion export (GO:0071436)3.44978815
70virion attachment to host cell (GO:0019062)3.42605529
71adhesion of symbiont to host cell (GO:0044650)3.42605529
72long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)3.40557036
73neuronal action potential propagation (GO:0019227)3.36744820
74synaptic transmission, glutamatergic (GO:0035249)3.32349707
75regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.30136292
76glutamate receptor signaling pathway (GO:0007215)3.29479105
77exploration behavior (GO:0035640)3.27224193
78nerve growth factor signaling pathway (GO:0038180)3.26371174
79regulation of respiratory system process (GO:0044065)3.23444019
80locomotory exploration behavior (GO:0035641)3.22740062
81negative regulation of execution phase of apoptosis (GO:1900118)3.20534219
82catecholamine transport (GO:0051937)3.20365216
83long-chain fatty-acyl-CoA metabolic process (GO:0035336)3.19982634
84negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.19440761
85regulation of respiratory gaseous exchange (GO:0043576)3.19332609
86positive regulation of synapse assembly (GO:0051965)3.18394646
87protein palmitoylation (GO:0018345)3.18011550
88response to redox state (GO:0051775)3.17692286
89membrane tubulation (GO:0097320)3.16267953
90positive regulation of synapse maturation (GO:0090129)3.16165722
91potassium ion homeostasis (GO:0055075)3.15655068
92limb bud formation (GO:0060174)3.13792073
93negative regulation of axonogenesis (GO:0050771)3.13208579
94organ growth (GO:0035265)3.12919979
95glycosylceramide metabolic process (GO:0006677)3.12485092
96dopamine metabolic process (GO:0042417)3.10687535
97regulation of long-term neuronal synaptic plasticity (GO:0048169)3.10508192
98acidic amino acid transport (GO:0015800)3.10377185
99amyloid precursor protein metabolic process (GO:0042982)3.09737180
100cellular response to nicotine (GO:0071316)3.09379264
101sterol biosynthetic process (GO:0016126)3.05565016
102magnesium ion transport (GO:0015693)3.04060400
103neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)3.03877820
104regulation of glutamate receptor signaling pathway (GO:1900449)3.03248050
105neuron-neuron synaptic transmission (GO:0007270)3.02167816
106negative regulation of inclusion body assembly (GO:0090084)3.00848545
107cerebellar granule cell differentiation (GO:0021707)3.00589276
108GPI anchor metabolic process (GO:0006505)2.98436530
109regulation of synaptic transmission, glutamatergic (GO:0051966)2.98181750
110myelination in peripheral nervous system (GO:0022011)2.98038543
111peripheral nervous system axon ensheathment (GO:0032292)2.98038543
112regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.97506230
113GPI anchor biosynthetic process (GO:0006506)2.96956735
114neuron recognition (GO:0008038)2.96433590
115astrocyte differentiation (GO:0048708)2.96174678
116positive regulation of dendritic spine development (GO:0060999)2.96083642
117positive regulation of action potential (GO:0045760)2.95673009
118mechanosensory behavior (GO:0007638)2.95629558
119amino acid import (GO:0043090)2.93451803
120positive regulation of membrane potential (GO:0045838)2.93298031
121membrane depolarization during action potential (GO:0086010)2.91430681
122fatty-acyl-CoA biosynthetic process (GO:0046949)2.90727257
123positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.90148691
124regulation of excitatory postsynaptic membrane potential (GO:0060079)2.90092949
125neuronal ion channel clustering (GO:0045161)2.88361825
126positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.86901097
127cellular response to epinephrine stimulus (GO:0071872)2.85961490
128neuromuscular synaptic transmission (GO:0007274)2.85576092
129regulation of neurotransmitter transport (GO:0051588)2.85343327
130neuron remodeling (GO:0016322)2.84922940
131axon development (GO:0061564)2.80263728
132isoprenoid biosynthetic process (GO:0008299)2.80010927
133response to lipoprotein particle (GO:0055094)2.79955041
134regulation of neurotransmitter uptake (GO:0051580)2.76116492
135regulation of postsynaptic membrane potential (GO:0060078)2.75899463
136axonal fasciculation (GO:0007413)2.74328258
137histone H2B ubiquitination (GO:0033523)2.70980132
138cyclic nucleotide catabolic process (GO:0009214)2.70322027
139protein polyglutamylation (GO:0018095)2.70104198
140fatty-acyl-CoA metabolic process (GO:0035337)2.69753894
141neurotransmitter uptake (GO:0001504)2.68459929
142gamma-aminobutyric acid signaling pathway (GO:0007214)2.67751332
143preassembly of GPI anchor in ER membrane (GO:0016254)2.67444372
144negative regulation of JUN kinase activity (GO:0043508)2.66626221
145very long-chain fatty acid metabolic process (GO:0000038)2.66263490
146dendritic spine morphogenesis (GO:0060997)2.65690269
147regulation of dopamine metabolic process (GO:0042053)2.63911997
148regulation of catecholamine metabolic process (GO:0042069)2.63911997
149neurotransmitter catabolic process (GO:0042135)2.62932641
150mating behavior (GO:0007617)2.62875026
151positive regulation of glial cell differentiation (GO:0045687)2.61806655
152microtubule polymerization or depolymerization (GO:0031109)2.61323499
153glial cell development (GO:0021782)2.60919912
154membrane assembly (GO:0071709)2.60826540
155peripheral nervous system development (GO:0007422)2.60782261
156leukocyte migration involved in inflammatory response (GO:0002523)2.57891017
157Leydig cell differentiation (GO:0033327)2.57586442
158response to epinephrine (GO:0071871)2.57187266
159cellular response to catecholamine stimulus (GO:0071870)2.56062378
160cellular response to monoamine stimulus (GO:0071868)2.56062378
161interleukin-6-mediated signaling pathway (GO:0070102)2.54439246
162peptidyl-cysteine modification (GO:0018198)2.53052401
163nucleotide transmembrane transport (GO:1901679)2.52990799
164acrosome reaction (GO:0007340)2.52558214
165neural nucleus development (GO:0048857)2.52264688
166microtubule severing (GO:0051013)2.50206164
167negative regulation of axon extension (GO:0030517)2.50014219
168axon ensheathment in central nervous system (GO:0032291)11.3711286
169central nervous system myelination (GO:0022010)11.3711286

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.48557282
2GBX2_23144817_ChIP-Seq_PC3_Human3.23305601
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.47140227
4JARID2_20064375_ChIP-Seq_MESCs_Mouse2.44149922
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.43936370
6SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.39516501
7CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.32622546
8TAF15_26573619_Chip-Seq_HEK293_Human2.32412096
9EZH2_27304074_Chip-Seq_ESCs_Mouse2.28954174
10RNF2_18974828_ChIP-Seq_MESCs_Mouse2.15806798
11EZH2_18974828_ChIP-Seq_MESCs_Mouse2.15806798
12MTF2_20144788_ChIP-Seq_MESCs_Mouse2.13988591
13SUZ12_27294783_Chip-Seq_ESCs_Mouse2.09013040
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.08419480
15* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.08249269
16SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.07756554
17EZH2_27294783_Chip-Seq_ESCs_Mouse2.05488857
18VDR_22108803_ChIP-Seq_LS180_Human2.05200460
19EED_16625203_ChIP-ChIP_MESCs_Mouse2.00665874
20SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.98952157
21SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.92554390
22JARID2_20075857_ChIP-Seq_MESCs_Mouse1.87907552
23VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.86273376
24OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.85111851
25RNF2_27304074_Chip-Seq_ESCs_Mouse1.83639566
26DROSHA_22980978_ChIP-Seq_HELA_Human1.81463271
27ZFP57_27257070_Chip-Seq_ESCs_Mouse1.79952657
28GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.70945329
29CBX2_27304074_Chip-Seq_ESCs_Mouse1.70356415
30ER_23166858_ChIP-Seq_MCF-7_Human1.67605507
31AR_21572438_ChIP-Seq_LNCaP_Human1.66006349
32TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.65192429
33RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.61560682
34CDX2_19796622_ChIP-Seq_MESCs_Mouse1.60345735
35CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.59469610
36CTBP1_25329375_ChIP-Seq_LNCAP_Human1.58276660
37SMAD3_21741376_ChIP-Seq_EPCs_Human1.58229722
38RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.56323252
39ERG_21242973_ChIP-ChIP_JURKAT_Human1.54240474
40PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.51591466
41BMI1_23680149_ChIP-Seq_NPCS_Mouse1.48866124
42REST_21632747_ChIP-Seq_MESCs_Mouse1.48572970
43EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.47181196
44POU3F2_20337985_ChIP-ChIP_501MEL_Human1.45758600
45CTBP2_25329375_ChIP-Seq_LNCAP_Human1.45221869
46RARB_27405468_Chip-Seq_BRAIN_Mouse1.43757749
47STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.41674146
48RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.38589542
49PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.38173134
50ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.36541094
51* OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.33400844
52TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.31895686
53SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.28793338
54RNF2_27304074_Chip-Seq_NSC_Mouse1.28701563
55P300_19829295_ChIP-Seq_ESCs_Human1.27116576
56NR3C1_23031785_ChIP-Seq_PC12_Mouse1.25872166
57PIAS1_25552417_ChIP-Seq_VCAP_Human1.25391387
58P53_22127205_ChIP-Seq_FIBROBLAST_Human1.24787323
59FUS_26573619_Chip-Seq_HEK293_Human1.19289745
60SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.19218865
61TP53_20018659_ChIP-ChIP_R1E_Mouse1.18807788
62RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.18227278
63SOX2_21211035_ChIP-Seq_LN229_Gbm1.16776230
64WT1_19549856_ChIP-ChIP_CCG9911_Human1.15968208
65GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.15622652
66IKZF1_21737484_ChIP-ChIP_HCT116_Human1.14340788
67GATA1_26923725_Chip-Seq_HPCs_Mouse1.14220668
68REST_18959480_ChIP-ChIP_MESCs_Mouse1.14056680
69DNAJC2_21179169_ChIP-ChIP_NT2_Human1.13125156
70NANOG_18555785_Chip-Seq_ESCs_Mouse1.10872831
71SMAD4_21799915_ChIP-Seq_A2780_Human1.10836719
72STAT3_23295773_ChIP-Seq_U87_Human1.09004961
73CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08982730
74TAL1_26923725_Chip-Seq_HPCs_Mouse1.08848428
75SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.08577883
76EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.07488075
77AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.06247476
78AR_19668381_ChIP-Seq_PC3_Human1.06196523
79TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.05981739
80CMYC_18555785_Chip-Seq_ESCs_Mouse1.05777305
81SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.05645205
82RING1B_27294783_Chip-Seq_ESCs_Mouse1.05596758
83TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.04601818
84TOP2B_26459242_ChIP-Seq_MCF-7_Human1.04539264
85RING1B_27294783_Chip-Seq_NPCs_Mouse1.03052320
86TCF4_23295773_ChIP-Seq_U87_Human1.02628996
87TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01979630
88POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.01979630
89EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.01371941
90EP300_21415370_ChIP-Seq_HL-1_Mouse1.00169839
91WT1_25993318_ChIP-Seq_PODOCYTE_Human0.99806085
92CTCF_27219007_Chip-Seq_Bcells_Human0.99802907
93P300_18555785_Chip-Seq_ESCs_Mouse0.98305607
94MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.97307489
95UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.97231946
96SMAD4_21741376_ChIP-Seq_HESCs_Human0.97083777
97CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.97025629
98HTT_18923047_ChIP-ChIP_STHdh_Human0.96566680
99LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.96529226
100SUZ12_18555785_Chip-Seq_ESCs_Mouse0.96248206
101EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.95138563
102MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.94709432
103PRDM14_20953172_ChIP-Seq_ESCs_Human0.94120516
104E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.93866666
105YAP1_20516196_ChIP-Seq_MESCs_Mouse0.93802580
106RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.92694248
107SOX9_26525672_Chip-Seq_HEART_Mouse0.92606629
108NR3C1_21868756_ChIP-Seq_MCF10A_Human0.92559001
109GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.92438148
110LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.92065224
111KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.91519698
112CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.91292033
113EOMES_21245162_ChIP-Seq_HESCs_Human0.91034196
114NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.90306815
115PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.90125206
116MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.89309709
117RUNX2_22187159_ChIP-Seq_PCA_Human0.87573936
118IRF1_19129219_ChIP-ChIP_H3396_Human0.87174274
119NANOG_19829295_ChIP-Seq_ESCs_Human0.86705579
120SOX2_19829295_ChIP-Seq_ESCs_Human0.86705579
121ARNT_22903824_ChIP-Seq_MCF-7_Human0.86626858
122TRIM28_21343339_ChIP-Seq_HEK293_Human0.86351704
123TBL1_22424771_ChIP-Seq_293T_Human0.86311543
124PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.85984643
125AR_25329375_ChIP-Seq_VCAP_Human0.84373847
126SMAD3_21741376_ChIP-Seq_ESCs_Human0.83454787
127KDM2B_26808549_Chip-Seq_REH_Human0.81747013
128ZFP281_18757296_ChIP-ChIP_E14_Mouse0.81555523
129TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.81469908
130KDM2B_26808549_Chip-Seq_K562_Human0.81334517
131ZFP281_27345836_Chip-Seq_ESCs_Mouse0.79282285

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000920_abnormal_myelination5.06790494
2MP0003880_abnormal_central_pattern4.52186912
3MP0004270_analgesia3.46573183
4MP0003950_abnormal_plasma_membrane3.05601394
5MP0005410_abnormal_fertilization2.86175620
6MP0003690_abnormal_glial_cell2.80977876
7MP0004859_abnormal_synaptic_plasticity2.79952109
8MP0002272_abnormal_nervous_system2.69656196
9MP0001486_abnormal_startle_reflex2.67455485
10MP0003329_amyloid_beta_deposits2.66458276
11MP0004885_abnormal_endolymph2.52110045
12MP0004742_abnormal_vestibular_system2.48591268
13MP0005171_absent_coat_pigmentation2.48148685
14MP0002064_seizures2.45362360
15MP0001905_abnormal_dopamine_level2.28077357
16MP0005409_darkened_coat_color2.23534344
17MP0001485_abnormal_pinna_reflex2.21829333
18MP0001529_abnormal_vocalization2.21312698
19MP0003136_yellow_coat_color2.17533520
20MP0000778_abnormal_nervous_system2.17019824
21MP0003634_abnormal_glial_cell2.15871163
22MP0003635_abnormal_synaptic_transmissio2.15269683
23MP0000569_abnormal_digit_pigmentation2.10269031
24MP0002638_abnormal_pupillary_reflex2.08703937
25MP0004142_abnormal_muscle_tone2.08301247
26MP0005423_abnormal_somatic_nervous2.07924109
27MP0009046_muscle_twitch2.05696670
28MP0009745_abnormal_behavioral_response2.04566971
29MP0002229_neurodegeneration1.83591647
30MP0000462_abnormal_digestive_system1.81168046
31MP0002734_abnormal_mechanical_nocicepti1.78412118
32MP0003632_abnormal_nervous_system1.73906519
33MP0001986_abnormal_taste_sensitivity1.62008330
34MP0001984_abnormal_olfaction1.59691888
35MP0000955_abnormal_spinal_cord1.56099174
36MP0002572_abnormal_emotion/affect_behav1.54935242
37MP0002063_abnormal_learning/memory/cond1.52626241
38MP0010678_abnormal_skin_adnexa1.52230975
39MP0000383_abnormal_hair_follicle1.49362016
40MP0005551_abnormal_eye_electrophysiolog1.48246769
41MP0002882_abnormal_neuron_morphology1.47048697
42MP0001440_abnormal_grooming_behavior1.44739841
43MP0004381_abnormal_hair_follicle1.43181909
44MP0002067_abnormal_sensory_capabilities1.42195033
45MP0005451_abnormal_body_composition1.42067883
46MP0009379_abnormal_foot_pigmentation1.38557851
47MP0004043_abnormal_pH_regulation1.37584897
48MP0003631_nervous_system_phenotype1.37518297
49MP0000566_synostosis1.36297147
50MP0008569_lethality_at_weaning1.35887550
51MP0002066_abnormal_motor_capabilities/c1.33286981
52MP0008260_abnormal_autophagy1.31950825
53MP0001963_abnormal_hearing_physiology1.31520487
54MP0000604_amyloidosis1.27145848
55MP0005187_abnormal_penis_morphology1.26743499
56MP0001970_abnormal_pain_threshold1.25920689
57MP0003938_abnormal_ear_development1.22661311
58MP0004924_abnormal_behavior1.21947153
59MP0005386_behavior/neurological_phenoty1.21947153
60MP0002752_abnormal_somatic_nervous1.21745241
61MP0001299_abnormal_eye_distance/1.21107630
62MP0003633_abnormal_nervous_system1.20304060
63MP0004133_heterotaxia1.17046671
64MP0004147_increased_porphyrin_level1.13429097
65MP0002733_abnormal_thermal_nociception1.12830600
66MP0002653_abnormal_ependyma_morphology1.11776285
67MP0005623_abnormal_meninges_morphology1.10853218
68MP0001968_abnormal_touch/_nociception1.10057247
69MP0002909_abnormal_adrenal_gland1.09410120
70MP0003283_abnormal_digestive_organ1.08063930
71MP0001346_abnormal_lacrimal_gland1.07101441
72MP0001348_abnormal_lacrimal_gland1.04275331
73MP0000747_muscle_weakness0.99294698
74MP0004145_abnormal_muscle_electrophysio0.98479936
75MP0001188_hyperpigmentation0.96851025
76MP0002152_abnormal_brain_morphology0.95529012
77MP0000026_abnormal_inner_ear0.94593979
78MP0008872_abnormal_physiological_respon0.94294857
79MP0005195_abnormal_posterior_eye0.93459010
80MP0003879_abnormal_hair_cell0.92019099
81MP0001851_eye_inflammation0.90589210
82MP0002735_abnormal_chemical_nociception0.90241365
83MP0003698_abnormal_male_reproductive0.89626044
84MP0003195_calcinosis0.89269775
85MP0002184_abnormal_innervation0.86430622
86MP0003119_abnormal_digestive_system0.86246637
87MP0002234_abnormal_pharynx_morphology0.85468901
88MP0000762_abnormal_tongue_morphology0.85109494
89MP0002822_catalepsy0.85089379
90MP0003122_maternal_imprinting0.84718507
91MP0001502_abnormal_circadian_rhythm0.83532951
92MP0004134_abnormal_chest_morphology0.83173263
93MP0002557_abnormal_social/conspecific_i0.83005310
94MP0005253_abnormal_eye_physiology0.82826132
95MP0003137_abnormal_impulse_conducting0.80753217
96MP0000467_abnormal_esophagus_morphology0.80537164
97MP0000647_abnormal_sebaceous_gland0.80060306
98MP0006072_abnormal_retinal_apoptosis0.77627961
99MP0003861_abnormal_nervous_system0.77070381
100MP0004811_abnormal_neuron_physiology0.75871044
101MP0002736_abnormal_nociception_after0.74556158
102MP0003937_abnormal_limbs/digits/tail_de0.74262691
103MP0005645_abnormal_hypothalamus_physiol0.73718920
104MP0001177_atelectasis0.72289623
105MP0002295_abnormal_pulmonary_circulatio0.72192220
106MP0002069_abnormal_eating/drinking_beha0.72143124
107MP0000049_abnormal_middle_ear0.71595926
108MP0001727_abnormal_embryo_implantation0.70871070
109MP0002938_white_spotting0.70416605
110MP0002102_abnormal_ear_morphology0.68903036
111MP0000631_abnormal_neuroendocrine_gland0.68671651
112MP0003787_abnormal_imprinting0.67704590
113MP0000579_abnormal_nail_morphology0.67126050
114MP0002751_abnormal_autonomic_nervous0.67079324
115MP0005379_endocrine/exocrine_gland_phen0.66582744
116MP0003123_paternal_imprinting0.65738535
117MP0001501_abnormal_sleep_pattern0.64896917
118MP0005646_abnormal_pituitary_gland0.64800922
119MP0006276_abnormal_autonomic_nervous0.62156874
120MP0000639_abnormal_adrenal_gland0.60714627
121MP0004036_abnormal_muscle_relaxation0.60421795
122MP0001943_abnormal_respiration0.60390048
123MP0000534_abnormal_ureter_morphology0.59627391
124MP0001661_extended_life_span0.59587657
125MP0001340_abnormal_eyelid_morphology0.59515073
126MP0005535_abnormal_body_temperature0.58690446
127MP0005167_abnormal_blood-brain_barrier0.56835932
128MP0010769_abnormal_survival0.54088423
129MP0010770_preweaning_lethality0.53963017
130MP0002082_postnatal_lethality0.53963017

Predicted human phenotypes

RankGene SetZ-score
1Limb dystonia (HP:0002451)7.84998071
2Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)6.28561679
3Degeneration of the lateral corticospinal tracts (HP:0002314)6.28561679
4Neurofibrillary tangles (HP:0002185)6.15570225
5Sensory axonal neuropathy (HP:0003390)4.86839429
6Peripheral hypomyelination (HP:0007182)4.80035772
7Abnormality of the corticospinal tract (HP:0002492)4.72062458
8Parakeratosis (HP:0001036)4.63351765
9Cerebral inclusion bodies (HP:0100314)4.43016074
10Cerebral hypomyelination (HP:0006808)4.14319168
11Spastic gait (HP:0002064)3.91015977
12Supranuclear gaze palsy (HP:0000605)3.70105792
13Abnormality of binocular vision (HP:0011514)3.66508574
14Diplopia (HP:0000651)3.66508574
15Onion bulb formation (HP:0003383)3.63524018
16Myokymia (HP:0002411)3.56615224
17Insidious onset (HP:0003587)3.51660494
18Termporal pattern (HP:0011008)3.51660494
19Abnormal eating behavior (HP:0100738)3.50670659
20Postural instability (HP:0002172)3.49457618
21Intention tremor (HP:0002080)3.48376393
22Febrile seizures (HP:0002373)3.46416806
23Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.45325523
24Alacrima (HP:0000522)3.42811913
25Dysmetria (HP:0001310)3.41996873
26Abnormal auditory evoked potentials (HP:0006958)3.19985065
27Generalized tonic-clonic seizures (HP:0002069)3.18261806
28Retinal dysplasia (HP:0007973)3.13110737
29Hemiparesis (HP:0001269)3.04787361
30Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)3.03113066
31Ankle clonus (HP:0011448)3.02242880
32Absent/shortened dynein arms (HP:0200106)2.92320382
33Dynein arm defect of respiratory motile cilia (HP:0012255)2.92320382
34Scanning speech (HP:0002168)2.89110730
35Progressive cerebellar ataxia (HP:0002073)2.81269297
36Hemiplegia (HP:0002301)2.75321796
37Polyphagia (HP:0002591)2.74727359
38Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.73984003
39Slow saccadic eye movements (HP:0000514)2.73598114
40Leukodystrophy (HP:0002415)2.72482927
41Dialeptic seizures (HP:0011146)2.72286813
42Decreased lacrimation (HP:0000633)2.68837936
43Spastic paraparesis (HP:0002313)2.68811524
44Focal motor seizures (HP:0011153)2.66303539
45Visual hallucinations (HP:0002367)2.65096065
46Absent septum pellucidum (HP:0001331)2.64103945
47Rigidity (HP:0002063)2.61718072
48Clumsiness (HP:0002312)2.61099140
49Increased hepatocellular lipid droplets (HP:0006565)2.58745959
50Hypokinesia (HP:0002375)2.56214483
51Aplasia involving bones of the extremities (HP:0009825)2.54027439
52Aplasia involving bones of the upper limbs (HP:0009823)2.54027439
53Aplasia of the phalanges of the hand (HP:0009802)2.54027439
54Thickened helices (HP:0000391)2.50966548
55Increased circulating renin level (HP:0000848)2.49402916
56Split foot (HP:0001839)2.45483316
57CNS hypomyelination (HP:0003429)2.45420871
58Hypoplastic pelvis (HP:0008839)2.45026881
59Diminished movement (HP:0002374)2.44988113
60Akinesia (HP:0002304)2.44915706
61Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.43437468
62Anteriorly placed anus (HP:0001545)2.42801308
63Absence seizures (HP:0002121)2.39976386
64Bradykinesia (HP:0002067)2.39889117
65Rapidly progressive (HP:0003678)2.35856155
66Congenital ichthyosiform erythroderma (HP:0007431)2.31580781
67Stridor (HP:0010307)2.30189309
68Torticollis (HP:0000473)2.30138973
69Ulnar claw (HP:0001178)2.29849957
70Morphological abnormality of the inner ear (HP:0011390)2.28496212
71Lower limb muscle weakness (HP:0007340)2.26913588
72Truncal ataxia (HP:0002078)2.24990052
73Cerebral hemorrhage (HP:0001342)2.23108833
74Hypomagnesemia (HP:0002917)2.21694149
75Lipid accumulation in hepatocytes (HP:0006561)2.21502521
76Abnormality of the septum pellucidum (HP:0007375)2.21474033
77Poor speech (HP:0002465)2.21343162
78Coronal craniosynostosis (HP:0004440)2.19028486
79Concave nail (HP:0001598)2.18124187
80Segmental peripheral demyelination/remyelination (HP:0003481)2.16823295
81Premature skin wrinkling (HP:0100678)2.15851868
82Drooling (HP:0002307)2.15401329
83Pheochromocytoma (HP:0002666)2.13073862
84Status epilepticus (HP:0002133)2.11471708
85Autoamputation (HP:0001218)2.10893410
86Renal Fanconi syndrome (HP:0001994)2.10151401
87Abnormal respiratory motile cilium physiology (HP:0012261)2.10010236
88Poor eye contact (HP:0000817)2.09960755
89Urinary bladder sphincter dysfunction (HP:0002839)2.09786627
90Muscular hypotonia of the trunk (HP:0008936)2.06595770
91White forelock (HP:0002211)2.06027132
92Hypoplasia of the iris (HP:0007676)2.04175933
93Metabolic alkalosis (HP:0200114)2.03851690
94Oligodactyly (hands) (HP:0001180)2.03213901
95Infantile muscular hypotonia (HP:0008947)2.02897709
96Esophageal atresia (HP:0002032)2.02727445
97Sleep apnea (HP:0010535)2.02360827
98Decreased motor nerve conduction velocity (HP:0003431)2.01928504
99Megalencephaly (HP:0001355)2.01262592
100Patchy hypopigmentation of hair (HP:0011365)2.00729096
101Annular pancreas (HP:0001734)2.00465856
102Urinary urgency (HP:0000012)1.99999106
103Spastic tetraparesis (HP:0001285)1.99979348
104Partial duplication of the phalanx of hand (HP:0009999)1.99670766
105Epileptiform EEG discharges (HP:0011182)1.98854686
106Foot dorsiflexor weakness (HP:0009027)1.96384598
107Abnormal ciliary motility (HP:0012262)1.95466040
108Excessive salivation (HP:0003781)1.94837162
109Paraparesis (HP:0002385)1.94638346
110Partial duplication of thumb phalanx (HP:0009944)1.94529878
111Amblyopia (HP:0000646)1.93161570
112Epileptic encephalopathy (HP:0200134)1.93139858
113Generalized myoclonic seizures (HP:0002123)1.92994257
114Clonus (HP:0002169)1.91907111
115Bowel incontinence (HP:0002607)1.91904879
116Morphological abnormality of the pyramidal tract (HP:0002062)1.91724226
117Hyperventilation (HP:0002883)1.88595714
118Action tremor (HP:0002345)1.88028653
119Abnormality of the phalanges of the 2nd finger (HP:0009541)1.86143301
120Adrenal hypoplasia (HP:0000835)1.85365155
121Type II lissencephaly (HP:0007260)1.85174975
122Partial agenesis of the corpus callosum (HP:0001338)1.85143205
123Abnormality of glycolysis (HP:0004366)1.84638307
124Increased serum pyruvate (HP:0003542)1.84638307
125Atonic seizures (HP:0010819)1.84199191
126EEG with generalized epileptiform discharges (HP:0011198)1.83781957
127Incomplete penetrance (HP:0003829)1.82759065
128Ventricular fibrillation (HP:0001663)1.82698690
129Synostosis involving the elbow (HP:0003938)1.82571303
130Humeroradial synostosis (HP:0003041)1.82571303
131Neuroendocrine neoplasm (HP:0100634)1.82459208
132Choreoathetosis (HP:0001266)1.81897840
133Dysdiadochokinesis (HP:0002075)1.81544464
134Turricephaly (HP:0000262)1.81298043
135Gait imbalance (HP:0002141)1.81143422
136Septo-optic dysplasia (HP:0100842)1.80849086
137Focal seizures (HP:0007359)1.80813567
138Hypsarrhythmia (HP:0002521)1.80218416
139Broad-based gait (HP:0002136)1.79937953
140Esotropia (HP:0000565)1.79719527
141Axonal loss (HP:0003447)1.79165922
142Buphthalmos (HP:0000557)1.78754280
143Abnormality of the periventricular white matter (HP:0002518)1.78495828
144Urinary incontinence (HP:0000020)1.78283075
145Anxiety (HP:0000739)1.77624849
146Mask-like facies (HP:0000298)1.77221459
147Abnormality of the foot musculature (HP:0001436)1.76964157
148Cupped ear (HP:0000378)1.75961838
149Impaired vibration sensation in the lower limbs (HP:0002166)1.75712392
150Muscle fiber splitting (HP:0003555)1.75288684
151Gaze-evoked nystagmus (HP:0000640)1.75175932
152Abnormal large intestine physiology (HP:0012700)1.74672801
153Focal dystonia (HP:0004373)1.73559877

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK396.24155787
2OXSR14.70028982
3CDK193.18648117
4EPHB12.83778273
5WNK42.59062339
6PKN12.58268481
7BCR2.48788590
8MET2.22060790
9FGFR22.19003056
10ICK2.11446313
11PBK2.09054935
12WNK11.98554049
13TNIK1.95063046
14PNCK1.90163911
15MAPKAPK51.89404234
16PINK11.86533465
17NEK61.85182470
18PRPF4B1.82330784
19CASK1.81236106
20UHMK11.77950409
21NTRK11.64435034
22DAPK21.60523126
23EPHA41.57541259
24GRK51.55849737
25CAMK2B1.54438715
26TESK21.53505426
27CSNK1G31.52181088
28PLK21.49816143
29ROCK21.49476392
30LIMK11.49333782
31CLK11.47768918
32PAK61.47433694
33CSNK1A1L1.44561025
34PRKCG1.27761208
35MARK11.27738438
36CAMK2D1.24156593
37FGR1.22934513
38CSNK1G11.17201466
39CAMKK11.16051031
40CSNK1G21.14415444
41PAK31.11458001
42MARK21.09061464
43SGK4941.08017061
44SGK2231.08017061
45TYRO31.06446648
46DYRK20.98819698
47CAMK2G0.97916526
48CDK50.95981335
49LATS20.94121345
50SGK20.93966087
51CDK140.91351104
52WEE10.88274103
53CAMK2A0.85862289
54CDK150.82655130
55PRKCZ0.82382063
56BLK0.82162921
57MAP4K20.81807069
58PRKD30.81344971
59MAP2K40.79378306
60TSSK60.78422002
61CDK180.77081467
62PRKCQ0.75902767
63CAMK1D0.75088546
64BMPR1B0.75069973
65CDK11A0.73608432
66PHKG20.73494714
67PHKG10.73494714
68NTRK30.73300909
69BUB10.72698568
70IRAK20.72425562
71CAMK10.72068339
72MAP3K110.71756312
73MAP2K70.70890022
74PDPK10.69137442
75MUSK0.68994708
76PRKD10.64704095
77CDK30.62114954
78NTRK20.62002101
79SGK10.61604859
80MAPK150.61010443
81PRKCE0.60780104
82STK110.59876262
83RIPK40.57487202
84INSRR0.57251173
85MAP3K120.56929591
86ERBB40.56561397
87MST40.55682880
88DDR20.55012337
89FYN0.54979727
90ALK0.53932731
91FES0.53751441
92TLK10.53542243
93IRAK10.52788494
94PTK2B0.51484761
95MAP3K90.50422946
96MAP3K130.49548574
97PRKG10.49367545
98RPS6KA30.48096386
99PRKD20.48028478
100MAPK130.47612254
101ARAF0.47034344
102MAP3K40.46014160
103CSNK1D0.45334429
104TAF10.43979255
105PRKCH0.41450277
106SIK20.40658134
107PDK10.39488384
108CSNK1A10.38474781
109LATS10.38368716
110GSK3A0.37978376
111ERBB30.37739749
112SGK30.37109717
113DYRK1A0.36511806
114MAPK120.36077797
115RPS6KA50.35903426
116PRKACB0.35138213
117PDGFRB0.33107016
118ROCK10.31655022
119STK380.30659094
120PIK3CA0.30600352
121CAMK1G0.30523269
122TRPM70.30492485
123CSNK1E0.30187801
124DAPK30.29761945
125MINK10.29390730
126PAK10.28954501
127MAPK70.28672963
128RET0.28641398
129PRKCA0.28408027
130PDK20.28175190
131KSR20.27657228
132MAPK100.27543803
133ADRBK20.26645959
134PRKACA0.25869297
135MAPK40.25121845
136MAP2K20.24859774
137ILK0.24848093

Predicted pathways (KEGG)

RankGene SetZ-score
1Terpenoid backbone biosynthesis_Homo sapiens_hsa009004.56316950
2Fatty acid elongation_Homo sapiens_hsa000624.07775374
3Steroid biosynthesis_Homo sapiens_hsa001003.74110871
4Ether lipid metabolism_Homo sapiens_hsa005652.94718936
5Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.88964531
6Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.70179467
7Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.17809999
8Axon guidance_Homo sapiens_hsa043602.06437832
9Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.04286167
10Vitamin B6 metabolism_Homo sapiens_hsa007501.82538739
11Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.80544432
12Oxidative phosphorylation_Homo sapiens_hsa001901.79115837
13GABAergic synapse_Homo sapiens_hsa047271.76945579
14Sphingolipid metabolism_Homo sapiens_hsa006001.73358240
15Linoleic acid metabolism_Homo sapiens_hsa005911.67128102
16Sulfur metabolism_Homo sapiens_hsa009201.65866809
17Glutamatergic synapse_Homo sapiens_hsa047241.61404808
18Morphine addiction_Homo sapiens_hsa050321.55538251
19Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.51133278
20Serotonergic synapse_Homo sapiens_hsa047261.48485662
21alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.47735066
22Histidine metabolism_Homo sapiens_hsa003401.46561382
23Nicotine addiction_Homo sapiens_hsa050331.42422442
24Protein export_Homo sapiens_hsa030601.42174158
25Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.41576312
26Aldosterone synthesis and secretion_Homo sapiens_hsa049251.39249876
27Nitrogen metabolism_Homo sapiens_hsa009101.35813647
28Long-term depression_Homo sapiens_hsa047301.31467637
29Renal cell carcinoma_Homo sapiens_hsa052111.25504281
30Alzheimers disease_Homo sapiens_hsa050101.23300302
31beta-Alanine metabolism_Homo sapiens_hsa004101.22449826
32Parkinsons disease_Homo sapiens_hsa050121.21940663
33Cocaine addiction_Homo sapiens_hsa050301.18337670
34Circadian entrainment_Homo sapiens_hsa047131.15968548
35Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.15786025
36Butanoate metabolism_Homo sapiens_hsa006501.12229758
37Bile secretion_Homo sapiens_hsa049761.11998529
38Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.11137867
39Arginine and proline metabolism_Homo sapiens_hsa003301.10643403
40Estrogen signaling pathway_Homo sapiens_hsa049151.10041576
41Cardiac muscle contraction_Homo sapiens_hsa042601.08112775
42Vibrio cholerae infection_Homo sapiens_hsa051101.05294873
43Salivary secretion_Homo sapiens_hsa049701.04963675
44Phototransduction_Homo sapiens_hsa047441.02717800
45Synaptic vesicle cycle_Homo sapiens_hsa047211.01079443
46Collecting duct acid secretion_Homo sapiens_hsa049661.00926583
47Endocytosis_Homo sapiens_hsa041440.95906519
48Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.94653669
49Gastric acid secretion_Homo sapiens_hsa049710.94408481
50Tight junction_Homo sapiens_hsa045300.94284992
51Dopaminergic synapse_Homo sapiens_hsa047280.91433988
52Vascular smooth muscle contraction_Homo sapiens_hsa042700.90045280
53Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.88619324
54Dorso-ventral axis formation_Homo sapiens_hsa043200.85747992
55Circadian rhythm_Homo sapiens_hsa047100.85469934
56Ras signaling pathway_Homo sapiens_hsa040140.84040184
57Sphingolipid signaling pathway_Homo sapiens_hsa040710.83154753
58Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.82949994
59Renin secretion_Homo sapiens_hsa049240.82432351
60Glycerophospholipid metabolism_Homo sapiens_hsa005640.80854561
61Phospholipase D signaling pathway_Homo sapiens_hsa040720.80807834
62ErbB signaling pathway_Homo sapiens_hsa040120.79211264
63SNARE interactions in vesicular transport_Homo sapiens_hsa041300.77872387
64GnRH signaling pathway_Homo sapiens_hsa049120.77450957
65Amphetamine addiction_Homo sapiens_hsa050310.77011077
66Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.76906375
67Thyroid hormone synthesis_Homo sapiens_hsa049180.75825926
68Taste transduction_Homo sapiens_hsa047420.75716924
69Gap junction_Homo sapiens_hsa045400.75500645
70Cholinergic synapse_Homo sapiens_hsa047250.74300466
71Ovarian steroidogenesis_Homo sapiens_hsa049130.72394520
72Arachidonic acid metabolism_Homo sapiens_hsa005900.71355161
73Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.70025412
74cGMP-PKG signaling pathway_Homo sapiens_hsa040220.68174126
75Autoimmune thyroid disease_Homo sapiens_hsa053200.67589349
76Pancreatic secretion_Homo sapiens_hsa049720.66540033
77Huntingtons disease_Homo sapiens_hsa050160.65699582
78Long-term potentiation_Homo sapiens_hsa047200.65693471
79Rheumatoid arthritis_Homo sapiens_hsa053230.65224057
80Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.64689005
81Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.62419591
82Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.61413770
83cAMP signaling pathway_Homo sapiens_hsa040240.57737234
84Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.57666989
85Regulation of actin cytoskeleton_Homo sapiens_hsa048100.57071040
86Oocyte meiosis_Homo sapiens_hsa041140.56830044
87Rap1 signaling pathway_Homo sapiens_hsa040150.56760694
88Hippo signaling pathway_Homo sapiens_hsa043900.56590189
89Olfactory transduction_Homo sapiens_hsa047400.56287889
90Regulation of autophagy_Homo sapiens_hsa041400.56039856
91Fatty acid biosynthesis_Homo sapiens_hsa000610.55120073
92Hedgehog signaling pathway_Homo sapiens_hsa043400.53983306
93ABC transporters_Homo sapiens_hsa020100.52201336
94Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.52176550
95Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.51921786
96Oxytocin signaling pathway_Homo sapiens_hsa049210.51742373
97Mineral absorption_Homo sapiens_hsa049780.51404779
98Prion diseases_Homo sapiens_hsa050200.51186323
99Calcium signaling pathway_Homo sapiens_hsa040200.51057303
100Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.49550741
101Glutathione metabolism_Homo sapiens_hsa004800.48486759
102Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.47245449
103Insulin secretion_Homo sapiens_hsa049110.46903375
104Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.46735567
105Alcoholism_Homo sapiens_hsa050340.45967129
106Dilated cardiomyopathy_Homo sapiens_hsa054140.45567330
107Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.44957851
108MAPK signaling pathway_Homo sapiens_hsa040100.44412324
109Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.42299247
110Fatty acid metabolism_Homo sapiens_hsa012120.40907947
111Inositol phosphate metabolism_Homo sapiens_hsa005620.40456641
112Choline metabolism in cancer_Homo sapiens_hsa052310.40226607
113Lysosome_Homo sapiens_hsa041420.39833243
114Type II diabetes mellitus_Homo sapiens_hsa049300.39367939
115Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.38517480
116Phagosome_Homo sapiens_hsa041450.38262682
117Steroid hormone biosynthesis_Homo sapiens_hsa001400.37881076
118Propanoate metabolism_Homo sapiens_hsa006400.37023011
119Phosphatidylinositol signaling system_Homo sapiens_hsa040700.36125142
120Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.35769961
121Folate biosynthesis_Homo sapiens_hsa007900.34703182
122Maturity onset diabetes of the young_Homo sapiens_hsa049500.34362275
123Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.34167494
124Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.34015635
125Wnt signaling pathway_Homo sapiens_hsa043100.33571930
126Melanogenesis_Homo sapiens_hsa049160.32759527
127Neurotrophin signaling pathway_Homo sapiens_hsa047220.31795987
128Glioma_Homo sapiens_hsa052140.28087423
129Carbohydrate digestion and absorption_Homo sapiens_hsa049730.28036550
130Glucagon signaling pathway_Homo sapiens_hsa049220.27116252
131Tyrosine metabolism_Homo sapiens_hsa003500.25259042
132PPAR signaling pathway_Homo sapiens_hsa033200.24307307

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