GPR83

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.99085936
2regulation of short-term neuronal synaptic plasticity (GO:0048172)5.61189753
3vocalization behavior (GO:0071625)5.54479106
4regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.31136762
5synaptic vesicle maturation (GO:0016188)5.09501246
6regulation of glutamate receptor signaling pathway (GO:1900449)5.06902242
7synaptic vesicle exocytosis (GO:0016079)5.05143509
8synaptic transmission, dopaminergic (GO:0001963)5.00784000
9striatum development (GO:0021756)4.89956532
10prepulse inhibition (GO:0060134)4.85034949
11locomotory exploration behavior (GO:0035641)4.83119945
12regulation of synapse structural plasticity (GO:0051823)4.73171008
13neurotransmitter-gated ion channel clustering (GO:0072578)4.69382122
14regulation of long-term neuronal synaptic plasticity (GO:0048169)4.68887108
15regulation of synaptic vesicle exocytosis (GO:2000300)4.67536079
16synaptic vesicle docking involved in exocytosis (GO:0016081)4.65803080
17positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.63896012
18behavioral response to nicotine (GO:0035095)4.62823356
19ionotropic glutamate receptor signaling pathway (GO:0035235)4.62599224
20regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.61798250
21positive regulation of synaptic transmission, dopaminergic (GO:0032226)4.61236454
22neurotransmitter secretion (GO:0007269)4.55996559
23protein localization to synapse (GO:0035418)4.54625061
24neuron-neuron synaptic transmission (GO:0007270)4.53088971
25neuronal action potential propagation (GO:0019227)4.46600282
26regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)4.46022912
27regulation of dopamine uptake involved in synaptic transmission (GO:0051584)4.46022912
28positive regulation of synaptic transmission, GABAergic (GO:0032230)4.44419116
29membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.42945234
30regulation of neuronal synaptic plasticity (GO:0048168)4.41693275
31glutamate secretion (GO:0014047)4.38036475
32behavioral response to cocaine (GO:0048148)4.32042287
33positive regulation of neurotransmitter transport (GO:0051590)4.24980682
34regulation of glutamate secretion (GO:0014048)4.24946422
35negative regulation of synaptic transmission, glutamatergic (GO:0051967)4.24107600
36synaptic transmission, glutamatergic (GO:0035249)4.21922616
37adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)4.21329962
38response to pheromone (GO:0019236)4.17776670
39sulfation (GO:0051923)4.16866541
40neuron cell-cell adhesion (GO:0007158)4.16011771
41regulation of excitatory postsynaptic membrane potential (GO:0060079)4.15744734
42positive regulation of synaptic transmission, glutamatergic (GO:0051968)4.14153868
43regulation of synaptic vesicle transport (GO:1902803)4.11537298
44positive regulation of membrane potential (GO:0045838)4.10731214
45auditory behavior (GO:0031223)4.09649512
46response to histamine (GO:0034776)4.03506458
47long-term memory (GO:0007616)4.01227723
48glutamate receptor signaling pathway (GO:0007215)4.00506301
49gamma-aminobutyric acid transport (GO:0015812)3.97853910
50regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.97517837
51DNA deamination (GO:0045006)3.95743713
52fucose catabolic process (GO:0019317)3.93502216
53L-fucose metabolic process (GO:0042354)3.93502216
54L-fucose catabolic process (GO:0042355)3.93502216
55regulation of synaptic transmission, glutamatergic (GO:0051966)3.92944130
56negative regulation of synaptic transmission, GABAergic (GO:0032229)3.91714316
57limb bud formation (GO:0060174)3.91655821
58regulation of postsynaptic membrane potential (GO:0060078)3.88315669
59response to amphetamine (GO:0001975)3.87845649
60long-term synaptic potentiation (GO:0060291)3.87068683
61regulation of dendritic spine morphogenesis (GO:0061001)3.85026746
62gamma-aminobutyric acid signaling pathway (GO:0007214)3.78305744
63dopamine receptor signaling pathway (GO:0007212)3.75670822
64regulation of neurotransmitter uptake (GO:0051580)3.74829297
65G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.73117225
66transmission of nerve impulse (GO:0019226)3.69555359
67response to auditory stimulus (GO:0010996)3.69102670
68regulation of synaptic plasticity (GO:0048167)3.67824706
69positive regulation of neurotransmitter secretion (GO:0001956)3.66927231
70regulation of female receptivity (GO:0045924)3.62303018
71neurotransmitter transport (GO:0006836)3.56950285
72exploration behavior (GO:0035640)3.55660144
73regulation of synaptic transmission, GABAergic (GO:0032228)3.53496765
74female mating behavior (GO:0060180)3.53016739
75activation of protein kinase A activity (GO:0034199)3.52549932
76dendritic spine morphogenesis (GO:0060997)3.52381863
77negative regulation of amino acid transport (GO:0051956)3.50996776
78regulation of synaptic transmission, dopaminergic (GO:0032225)3.50424024
79regulation of mesoderm development (GO:2000380)3.49801094
80mechanosensory behavior (GO:0007638)3.49795200
81neuromuscular process controlling posture (GO:0050884)3.47243242
82neuronal ion channel clustering (GO:0045161)3.47040035
83regulation of neurotransmitter levels (GO:0001505)3.46473683
84behavioral defense response (GO:0002209)3.46163610
85behavioral fear response (GO:0001662)3.46163610
86membrane hyperpolarization (GO:0060081)3.43187897
87regulation of protein kinase A signaling (GO:0010738)3.42756530
88positive regulation of synaptic transmission (GO:0050806)3.37569270
89adenosine receptor signaling pathway (GO:0001973)3.37490123
90neuromuscular process controlling balance (GO:0050885)3.36739364
91regulation of neurotransmitter transport (GO:0051588)3.33832419
92water-soluble vitamin biosynthetic process (GO:0042364)3.33273888
93negative regulation of dendrite morphogenesis (GO:0050774)3.30633877
94presynaptic membrane assembly (GO:0097105)3.30034711
95membrane depolarization (GO:0051899)3.29423369
96negative regulation of dendrite development (GO:2000171)3.27677601
97learning (GO:0007612)3.24673798
98visual learning (GO:0008542)3.24614543
99DNA double-strand break processing (GO:0000729)3.24597850
100regulation of neurotransmitter secretion (GO:0046928)3.24476192
101reflex (GO:0060004)3.24197853
102regulation of vesicle fusion (GO:0031338)3.20135260
103cAMP catabolic process (GO:0006198)3.19019681
104negative regulation of cytosolic calcium ion concentration (GO:0051481)3.18801288
105regulation of dendritic spine development (GO:0060998)3.17864947
106proline transport (GO:0015824)3.17420497
107cerebellar Purkinje cell differentiation (GO:0021702)3.16320486
108synaptic transmission (GO:0007268)3.16314715
109protein polyglutamylation (GO:0018095)3.16030125
110layer formation in cerebral cortex (GO:0021819)3.15221667
111somite development (GO:0061053)3.14952043
112presynaptic membrane organization (GO:0097090)3.14113461
113regulation of voltage-gated calcium channel activity (GO:1901385)3.13168410
114positive regulation of synapse maturation (GO:0090129)3.12462504
115negative regulation of axon guidance (GO:1902668)3.05790265
116negative regulation of axon extension involved in axon guidance (GO:0048843)3.05653274
117detection of light stimulus involved in visual perception (GO:0050908)3.04738257
118detection of light stimulus involved in sensory perception (GO:0050962)3.04738257
119cell proliferation in forebrain (GO:0021846)3.03637644
120mitochondrial respiratory chain complex I assembly (GO:0032981)2.99360040
121NADH dehydrogenase complex assembly (GO:0010257)2.99360040
122mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.99360040
123negative regulation of mast cell activation (GO:0033004)2.98500024
124detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.97680952
125tryptophan catabolic process (GO:0006569)2.95914929
126indole-containing compound catabolic process (GO:0042436)2.95914929
127indolalkylamine catabolic process (GO:0046218)2.95914929
128G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.94872366
129prostate gland growth (GO:0060736)2.94789497
130regulation of collateral sprouting (GO:0048670)2.91677622
131indolalkylamine metabolic process (GO:0006586)2.88481383
132cellular response to ATP (GO:0071318)2.87370263
133primary amino compound metabolic process (GO:1901160)2.83330411
134regulation of DNA endoreduplication (GO:0032875)2.81612508
135kynurenine metabolic process (GO:0070189)2.79968582
136behavioral response to ethanol (GO:0048149)2.79128230
137neuronal action potential (GO:0019228)2.78494154
138protein complex biogenesis (GO:0070271)2.76105206
139righting reflex (GO:0060013)2.73484485
140kidney morphogenesis (GO:0060993)2.71859110
141serotonin metabolic process (GO:0042428)2.70353321
142endoderm formation (GO:0001706)2.68188511
143retinal ganglion cell axon guidance (GO:0031290)2.65302143
144postsynaptic membrane organization (GO:0001941)2.65068134
145protein localization to cilium (GO:0061512)2.63900935
146replication fork processing (GO:0031297)2.63467533
147negative regulation of transcription regulatory region DNA binding (GO:2000678)2.57513605
148membrane depolarization during action potential (GO:0086010)2.57293220
149indole-containing compound metabolic process (GO:0042430)2.57248553
150photoreceptor cell development (GO:0042461)2.56553732
151regulation of action potential (GO:0098900)2.56061217
152protein K11-linked deubiquitination (GO:0035871)2.55771255
153startle response (GO:0001964)2.55413111
154regulation of rhodopsin mediated signaling pathway (GO:0022400)2.55073515
155mitochondrial respiratory chain complex assembly (GO:0033108)2.55035177
1563-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)2.54517427
157purine ribonucleoside bisphosphate metabolic process (GO:0034035)2.54517427
158protein-cofactor linkage (GO:0018065)2.53663933
159positive regulation of meiosis (GO:0045836)2.50733699
160piRNA metabolic process (GO:0034587)2.50326467
161rhodopsin mediated signaling pathway (GO:0016056)2.49113150
162somite rostral/caudal axis specification (GO:0032525)2.48672027
163dopamine transport (GO:0015872)2.48628267
164negative regulation of membrane potential (GO:0045837)2.48596333
165regulation of glomerulus development (GO:0090192)2.48556207
166tryptophan metabolic process (GO:0006568)2.47884185
167pyrimidine nucleobase catabolic process (GO:0006208)2.47592724
168retinal cone cell development (GO:0046549)2.46450901
169negative regulation of axon extension (GO:0030517)2.44647743
170platelet dense granule organization (GO:0060155)2.43552735
171cornea development in camera-type eye (GO:0061303)2.43551230
172positive regulation of potassium ion transmembrane transport (GO:1901381)2.40992217
173negative regulation of systemic arterial blood pressure (GO:0003085)2.39799665
174activated T cell proliferation (GO:0050798)2.39466749
175cilium morphogenesis (GO:0060271)2.37631765
176adaptation of signaling pathway (GO:0023058)2.37278251
177negative regulation of telomere maintenance (GO:0032205)2.36735854
178regulation of glucokinase activity (GO:0033131)2.36344762
179regulation of hexokinase activity (GO:1903299)2.36344762

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.46192087
2GBX2_23144817_ChIP-Seq_PC3_Human3.78032055
3RARB_27405468_Chip-Seq_BRAIN_Mouse3.44073057
4* SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.27121174
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.19504595
6JARID2_20064375_ChIP-Seq_MESCs_Mouse3.14935873
7ZNF274_21170338_ChIP-Seq_K562_Hela3.12907073
8VDR_22108803_ChIP-Seq_LS180_Human2.84720234
9REST_21632747_ChIP-Seq_MESCs_Mouse2.83549188
10* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.71119754
11* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.69282027
12EZH2_18974828_ChIP-Seq_MESCs_Mouse2.67939020
13RNF2_18974828_ChIP-Seq_MESCs_Mouse2.67939020
14DROSHA_22980978_ChIP-Seq_HELA_Human2.59022228
15* SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.58268523
16EZH2_27304074_Chip-Seq_ESCs_Mouse2.53826644
17* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.53780365
18* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.51971914
19IKZF1_21737484_ChIP-ChIP_HCT116_Human2.47500805
20MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.40295373
21REST_18959480_ChIP-ChIP_MESCs_Mouse2.37119122
22* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.37014777
23CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.29454017
24TAF15_26573619_Chip-Seq_HEK293_Human2.29430894
25SUZ12_27294783_Chip-Seq_ESCs_Mouse2.29206576
26AR_21572438_ChIP-Seq_LNCaP_Human2.24718313
27CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.22490272
28EWS_26573619_Chip-Seq_HEK293_Human2.22270211
29* FUS_26573619_Chip-Seq_HEK293_Human2.15882961
30EZH2_27294783_Chip-Seq_ESCs_Mouse2.15238947
31RNF2_27304074_Chip-Seq_ESCs_Mouse2.14293565
32ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.09799659
33EED_16625203_ChIP-ChIP_MESCs_Mouse2.03385562
34GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.96798417
35CTBP2_25329375_ChIP-Seq_LNCAP_Human1.95771654
36FLI1_27457419_Chip-Seq_LIVER_Mouse1.94589337
37HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.90575425
38NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.86504347
39SALL1_21062744_ChIP-ChIP_HESCs_Human1.78587524
40EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.76942844
41GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.75412773
42CTBP1_25329375_ChIP-Seq_LNCAP_Human1.71741261
43SMAD4_21799915_ChIP-Seq_A2780_Human1.70729128
44ERG_21242973_ChIP-ChIP_JURKAT_Human1.68287216
45* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.68216873
46PCGF2_27294783_Chip-Seq_ESCs_Mouse1.63258388
47MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.61042597
48ZFP57_27257070_Chip-Seq_ESCs_Mouse1.60994484
49HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.57916040
50MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.49308213
51SMAD_19615063_ChIP-ChIP_OVARY_Human1.49291003
52* IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.48305823
53* CBP_20019798_ChIP-Seq_JUKART_Human1.48305823
54P300_19829295_ChIP-Seq_ESCs_Human1.45503494
55MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.44470039
56NR3C1_21868756_ChIP-Seq_MCF10A_Human1.41606126
57PCGF2_27294783_Chip-Seq_NPCs_Mouse1.40335048
58PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.38553072
59SMAD3_21741376_ChIP-Seq_EPCs_Human1.37918395
60DNAJC2_21179169_ChIP-ChIP_NT2_Human1.37121271
61SUZ12_27294783_Chip-Seq_NPCs_Mouse1.36766049
62PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.36393999
63VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.36013435
64* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.35932770
65EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.34974821
66EZH2_27294783_Chip-Seq_NPCs_Mouse1.34006033
67SOX2_21211035_ChIP-Seq_LN229_Gbm1.31008388
68FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.30711199
69* SMAD4_21741376_ChIP-Seq_EPCs_Human1.30162656
70RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.30049062
71IRF1_19129219_ChIP-ChIP_H3396_Human1.28769415
72TCF4_22108803_ChIP-Seq_LS180_Human1.28378135
73TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.27675021
74E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.27173099
75BMI1_23680149_ChIP-Seq_NPCS_Mouse1.26120446
76RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.25737636
77NFE2_27457419_Chip-Seq_LIVER_Mouse1.25299109
78P53_22127205_ChIP-Seq_FIBROBLAST_Human1.23262864
79TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.23191339
80TP53_22573176_ChIP-Seq_HFKS_Human1.22438065
81STAT3_23295773_ChIP-Seq_U87_Human1.22377089
82* NANOG_19829295_ChIP-Seq_ESCs_Human1.22012617
83* SOX2_19829295_ChIP-Seq_ESCs_Human1.22012617
84POU5F1_16153702_ChIP-ChIP_HESCs_Human1.21554734
85ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.21512408
86AR_25329375_ChIP-Seq_VCAP_Human1.19699260
87NOTCH1_21737748_ChIP-Seq_TLL_Human1.19655148
88EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.19010674
89RING1B_27294783_Chip-Seq_ESCs_Mouse1.18479822
90* KLF5_20875108_ChIP-Seq_MESCs_Mouse1.17811968
91NR3C1_23031785_ChIP-Seq_PC12_Mouse1.17329194
92GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.17203494
93TOP2B_26459242_ChIP-Seq_MCF-7_Human1.17138439
94AR_19668381_ChIP-Seq_PC3_Human1.15350562
95MYC_18940864_ChIP-ChIP_HL60_Human1.15345961
96CBX2_27304074_Chip-Seq_ESCs_Mouse1.14930377
97PRDM14_20953172_ChIP-Seq_ESCs_Human1.12880434
98RNF2_27304074_Chip-Seq_NSC_Mouse1.12802436
99OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.12597954
100P53_22387025_ChIP-Seq_ESCs_Mouse1.12577062
101CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.12552198
102TCF4_23295773_ChIP-Seq_U87_Human1.10673582
103GABP_17652178_ChIP-ChIP_JURKAT_Human1.10572794
104MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.09511803
105EST1_17652178_ChIP-ChIP_JURKAT_Human1.09472399
106PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.08843710
107BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.06972427
108POU3F2_20337985_ChIP-ChIP_501MEL_Human1.06072353
109CRX_20693478_ChIP-Seq_RETINA_Mouse1.05901449
110SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.05453040
111PIAS1_25552417_ChIP-Seq_VCAP_Human1.05439884
112WT1_25993318_ChIP-Seq_PODOCYTE_Human1.04774264
113KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.04017151
114FOXA1_27270436_Chip-Seq_PROSTATE_Human1.02068644
115FOXA1_25329375_ChIP-Seq_VCAP_Human1.02068644
116RUNX2_22187159_ChIP-Seq_PCA_Human1.01869867
117TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.01182526
118FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.00878742
119UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.98509496
120AHR_22903824_ChIP-Seq_MCF-7_Human0.96350307
121ARNT_22903824_ChIP-Seq_MCF-7_Human0.95823062
122CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.95373487
123EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.94352166
124RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.94177512
125TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.94135289
126ZNF217_24962896_ChIP-Seq_MCF-7_Human0.92949766
127SMAD3_21741376_ChIP-Seq_HESCs_Human0.92633138
128RING1B_27294783_Chip-Seq_NPCs_Mouse0.92499980
129YAP1_20516196_ChIP-Seq_MESCs_Mouse0.92370561
130IGF1R_20145208_ChIP-Seq_DFB_Human0.92034061
131ER_23166858_ChIP-Seq_MCF-7_Human0.91300508
132GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.90982126
133RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.90761005
134CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89098273
135JUN_21703547_ChIP-Seq_K562_Human0.89010258
136* SMAD3_21741376_ChIP-Seq_ESCs_Human0.88101892
137POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.87680866
138TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87680866
139TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.87266495
140NANOG_18555785_Chip-Seq_ESCs_Mouse0.87184636
141SMAD4_21741376_ChIP-Seq_HESCs_Human0.86740048
142AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.85962126
143STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.84966470
144WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.84775714
145ZFP281_18757296_ChIP-ChIP_E14_Mouse0.84219357
146BCAT_22108803_ChIP-Seq_LS180_Human0.83307576
147FLI1_21867929_ChIP-Seq_TH2_Mouse0.82771834

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002822_catalepsy6.36802955
2MP0004859_abnormal_synaptic_plasticity6.18179678
3MP0003880_abnormal_central_pattern5.05259496
4MP0003635_abnormal_synaptic_transmissio4.30665125
5MP0009745_abnormal_behavioral_response3.95518943
6MP0002063_abnormal_learning/memory/cond3.49154248
7MP0009046_muscle_twitch3.48232383
8MP0002064_seizures3.43896001
9MP0004270_analgesia3.12390369
10MP0002572_abnormal_emotion/affect_behav3.04818541
11MP0001968_abnormal_touch/_nociception2.88112101
12MP0001486_abnormal_startle_reflex2.85763352
13MP0002272_abnormal_nervous_system2.82127171
14MP0001529_abnormal_vocalization2.72604920
15MP0001501_abnormal_sleep_pattern2.58166852
16MP0003195_calcinosis2.48910908
17MP0002653_abnormal_ependyma_morphology2.46938420
18MP0002102_abnormal_ear_morphology2.46678073
19MP0006072_abnormal_retinal_apoptosis2.27518701
20MP0005646_abnormal_pituitary_gland2.22937271
21MP0005423_abnormal_somatic_nervous2.21759995
22MP0002736_abnormal_nociception_after2.19541480
23MP0002734_abnormal_mechanical_nocicepti2.16929346
24MP0006292_abnormal_olfactory_placode2.07691974
25MP0000569_abnormal_digit_pigmentation1.97495887
26MP0001440_abnormal_grooming_behavior1.94148461
27MP0005386_behavior/neurological_phenoty1.92408226
28MP0004924_abnormal_behavior1.92408226
29MP0001970_abnormal_pain_threshold1.91539871
30MP0008569_lethality_at_weaning1.89208635
31MP0001984_abnormal_olfaction1.87933825
32MP0001986_abnormal_taste_sensitivity1.86586631
33MP0005253_abnormal_eye_physiology1.85673100
34MP0002909_abnormal_adrenal_gland1.84832074
35MP0002067_abnormal_sensory_capabilities1.84740558
36MP0003787_abnormal_imprinting1.83405191
37MP0002557_abnormal_social/conspecific_i1.80283852
38MP0002733_abnormal_thermal_nociception1.77524661
39MP0002751_abnormal_autonomic_nervous1.70557908
40MP0002735_abnormal_chemical_nociception1.70498832
41MP0003011_delayed_dark_adaptation1.64656644
42MP0003890_abnormal_embryonic-extraembry1.64085584
43MP0003879_abnormal_hair_cell1.59959953
44MP0001905_abnormal_dopamine_level1.59380842
45MP0004811_abnormal_neuron_physiology1.57282234
46MP0000049_abnormal_middle_ear1.55881016
47MP0009780_abnormal_chondrocyte_physiolo1.54988635
48MP0002160_abnormal_reproductive_system1.51974446
49MP0001188_hyperpigmentation1.51199015
50MP0004133_heterotaxia1.50441274
51MP0003122_maternal_imprinting1.48715085
52MP0008872_abnormal_physiological_respon1.48196420
53MP0002184_abnormal_innervation1.44908915
54MP0004145_abnormal_muscle_electrophysio1.35870849
55MP0002066_abnormal_motor_capabilities/c1.34540654
56MP0003119_abnormal_digestive_system1.34304856
57MP0005409_darkened_coat_color1.33612354
58MP0008874_decreased_physiological_sensi1.32487435
59MP0003633_abnormal_nervous_system1.25299087
60MP0004142_abnormal_muscle_tone1.23379317
61MP0006276_abnormal_autonomic_nervous1.22149702
62MP0004147_increased_porphyrin_level1.21867433
63MP0005389_reproductive_system_phenotype1.21539292
64MP0000955_abnormal_spinal_cord1.21512005
65MP0002938_white_spotting1.20435438
66MP0000013_abnormal_adipose_tissue1.20098431
67MP0000778_abnormal_nervous_system1.18480869
68MP0004215_abnormal_myocardial_fiber1.17701535
69MP0003329_amyloid_beta_deposits1.17362805
70MP0002882_abnormal_neuron_morphology1.17201280
71MP0003937_abnormal_limbs/digits/tail_de1.15872140
72MP0000372_irregular_coat_pigmentation1.12422075
73MP0005645_abnormal_hypothalamus_physiol1.09571411
74MP0001502_abnormal_circadian_rhythm1.06088984
75MP0003646_muscle_fatigue1.05954663
76MP0004885_abnormal_endolymph1.05551469
77MP0008995_early_reproductive_senescence1.04064800
78MP0003631_nervous_system_phenotype1.00133378
79MP0003567_abnormal_fetal_cardiomyocyte1.00132405
80MP0002138_abnormal_hepatobiliary_system0.99765710
81MP0002234_abnormal_pharynx_morphology0.99350292
82MP0000026_abnormal_inner_ear0.98574559
83MP0000383_abnormal_hair_follicle0.98345107
84MP0002069_abnormal_eating/drinking_beha0.96512927
85MP0005174_abnormal_tail_pigmentation0.95288125
86MP0003938_abnormal_ear_development0.93013366
87MP0003075_altered_response_to0.92801127
88MP0004134_abnormal_chest_morphology0.92298686
89MP0000427_abnormal_hair_cycle0.90106554
90MP0001177_atelectasis0.90086614
91MP0008961_abnormal_basal_metabolism0.88793958
92MP0002152_abnormal_brain_morphology0.88410606
93MP0000751_myopathy0.88292856
94MP0005535_abnormal_body_temperature0.88045444
95MP0008875_abnormal_xenobiotic_pharmacok0.85146252
96MP0003718_maternal_effect0.85098631
97MP0004085_abnormal_heartbeat0.84988522
98MP0005084_abnormal_gallbladder_morpholo0.84903874
99MP0009250_abnormal_appendicular_skeleto0.82680664
100MP0005167_abnormal_blood-brain_barrier0.80164187
101MP0005195_abnormal_posterior_eye0.79445551
102MP0004742_abnormal_vestibular_system0.77783931
103MP0002229_neurodegeneration0.77452177
104MP0000516_abnormal_urinary_system0.77267445
105MP0005367_renal/urinary_system_phenotyp0.77267445
106MP0002282_abnormal_trachea_morphology0.77001601
107MP0004858_abnormal_nervous_system0.76827648
108MP0002876_abnormal_thyroid_physiology0.74233253
109MP0000631_abnormal_neuroendocrine_gland0.74071450
110MP0010386_abnormal_urinary_bladder0.73495869
111MP0005499_abnormal_olfactory_system0.73175459
112MP0005394_taste/olfaction_phenotype0.73175459
113MP0002928_abnormal_bile_duct0.72163228
114MP0001664_abnormal_digestion0.71616046
115MP0001485_abnormal_pinna_reflex0.71371162
116MP0001919_abnormal_reproductive_system0.70103637
117MP0003690_abnormal_glial_cell0.70050872
118MP0000920_abnormal_myelination0.68522239
119MP0005551_abnormal_eye_electrophysiolog0.66920554
120MP0001963_abnormal_hearing_physiology0.65792812
121MP0002090_abnormal_vision0.62752411
122MP0005310_abnormal_salivary_gland0.61839700
123MP0002837_dystrophic_cardiac_calcinosis0.58111708
124MP0010234_abnormal_vibrissa_follicle0.57916788
125MP0000604_amyloidosis0.57480696
126MP0003121_genomic_imprinting0.56891731
127MP0002752_abnormal_somatic_nervous0.55073027
128MP0008877_abnormal_DNA_methylation0.54144175
129MP0003634_abnormal_glial_cell0.53317362
130MP0001943_abnormal_respiration0.52232240
131MP0002638_abnormal_pupillary_reflex0.51651548
132MP0003632_abnormal_nervous_system0.51600308
133MP0003866_abnormal_defecation0.51182788
134MP0003956_abnormal_body_size0.49738962
135MP0010769_abnormal_survival0.47011487
136MP0003137_abnormal_impulse_conducting0.46547343
137MP0002082_postnatal_lethality0.46063449
138MP0010770_preweaning_lethality0.46063449
139MP0003283_abnormal_digestive_organ0.44430294
140MP0010768_mortality/aging0.44076963
141MP0001765_abnormal_ion_homeostasis0.43293232
142MP0004484_altered_response_of0.41156215
143MP0003303_peritoneal_inflammation0.40275980

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)9.67787109
2Myokymia (HP:0002411)7.90361279
3Focal seizures (HP:0007359)6.44203249
4Atonic seizures (HP:0010819)5.78112843
5Febrile seizures (HP:0002373)5.27897642
6Epileptic encephalopathy (HP:0200134)5.22426061
7Absence seizures (HP:0002121)4.81805846
8Visual hallucinations (HP:0002367)4.71858670
9Dialeptic seizures (HP:0011146)4.42841241
10Pancreatic cysts (HP:0001737)4.33014434
11True hermaphroditism (HP:0010459)4.28251922
12Annular pancreas (HP:0001734)4.19298445
13Pancreatic fibrosis (HP:0100732)4.16005145
14Generalized tonic-clonic seizures (HP:0002069)4.14757022
15Broad-based gait (HP:0002136)3.94822052
16Pendular nystagmus (HP:0012043)3.77149777
17Hyperventilation (HP:0002883)3.69427987
18Progressive cerebellar ataxia (HP:0002073)3.67470420
19Resting tremor (HP:0002322)3.62686836
20Gaze-evoked nystagmus (HP:0000640)3.61239964
21Poor eye contact (HP:0000817)3.61118930
22Congenital stationary night blindness (HP:0007642)3.52820366
23Impaired vibration sensation in the lower limbs (HP:0002166)3.52337572
24Anxiety (HP:0000739)3.51544678
25Molar tooth sign on MRI (HP:0002419)3.50726139
26Abnormality of midbrain morphology (HP:0002418)3.50726139
27Abolished electroretinogram (ERG) (HP:0000550)3.44439491
28Impaired social interactions (HP:0000735)3.40158437
29Abnormal social behavior (HP:0012433)3.40158437
30Abnormal eating behavior (HP:0100738)3.32497439
31Depression (HP:0000716)3.25778464
32Progressive inability to walk (HP:0002505)3.23503881
33Nephronophthisis (HP:0000090)3.22365599
34Torticollis (HP:0000473)3.18324444
35Urinary bladder sphincter dysfunction (HP:0002839)3.15332548
36Ankle clonus (HP:0011448)3.15328117
37Truncal ataxia (HP:0002078)3.12632100
38Action tremor (HP:0002345)3.11201265
39Dysdiadochokinesis (HP:0002075)3.08163391
40Focal dystonia (HP:0004373)2.96226139
41Dysmetria (HP:0001310)2.91011489
42Cystic liver disease (HP:0006706)2.89136431
43Dysmetric saccades (HP:0000641)2.87548107
44Stereotypic behavior (HP:0000733)2.84532673
45Septo-optic dysplasia (HP:0100842)2.83164947
46Urinary urgency (HP:0000012)2.81056599
47Aplasia/Hypoplasia of the tibia (HP:0005772)2.80851252
48Abnormal hair whorl (HP:0010721)2.77583185
49Furrowed tongue (HP:0000221)2.76436927
50Abnormal rod and cone electroretinograms (HP:0008323)2.76409408
51Limb dystonia (HP:0002451)2.76127638
52Scanning speech (HP:0002168)2.75474007
53Craniofacial dystonia (HP:0012179)2.73453756
54Asplenia (HP:0001746)2.70128034
55Aplasia/Hypoplasia of the spleen (HP:0010451)2.69820794
56Absent rod-and cone-mediated responses on ERG (HP:0007688)2.67721306
57Amblyopia (HP:0000646)2.67059674
58Increased corneal curvature (HP:0100692)2.64575938
59Keratoconus (HP:0000563)2.64575938
60Abnormality of the renal medulla (HP:0100957)2.64037057
61Decreased central vision (HP:0007663)2.59089319
62Short tibia (HP:0005736)2.57043773
63Inability to walk (HP:0002540)2.56676949
64Status epilepticus (HP:0002133)2.55910783
65Impaired smooth pursuit (HP:0007772)2.55460131
66Attenuation of retinal blood vessels (HP:0007843)2.53823473
67Anomalous pulmonary venous return (HP:0010772)2.52450400
68Disproportionate short-trunk short stature (HP:0003521)2.52134606
69Aplasia/Hypoplasia of the tongue (HP:0010295)2.51910802
70Sclerocornea (HP:0000647)2.49496315
71Optic nerve hypoplasia (HP:0000609)2.47414466
72Spastic gait (HP:0002064)2.46695055
73Impaired vibratory sensation (HP:0002495)2.43391745
74Congenital, generalized hypertrichosis (HP:0004540)2.42419312
75Abnormality of the renal cortex (HP:0011035)2.41642859
76Bradykinesia (HP:0002067)2.40465393
77Postural instability (HP:0002172)2.38687545
78Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.37149241
79Hemiplegia (HP:0002301)2.34482225
80Abnormality of the pulmonary veins (HP:0011718)2.31955012
81Rib fusion (HP:0000902)2.30731890
82Lower limb amyotrophy (HP:0007210)2.30454883
83Chorioretinal atrophy (HP:0000533)2.29826578
84Methylmalonic acidemia (HP:0002912)2.27480317
85Polyphagia (HP:0002591)2.27191158
86Abnormality of the middle phalanx of the 5th finger (HP:0004219)2.27082428
87Hypothermia (HP:0002045)2.26294164
88Epileptiform EEG discharges (HP:0011182)2.25493417
89Medial flaring of the eyebrow (HP:0010747)2.24893164
90Abnormality of binocular vision (HP:0011514)2.23145690
91Diplopia (HP:0000651)2.23145690
92Anencephaly (HP:0002323)2.21276149
93Genetic anticipation (HP:0003743)2.19653624
94Conjunctival hamartoma (HP:0100780)2.19327599
95Small hand (HP:0200055)2.19214492
96Abnormality of ocular smooth pursuit (HP:0000617)2.19028611
97Generalized myoclonic seizures (HP:0002123)2.18821884
98Pointed chin (HP:0000307)2.17535718
99Drooling (HP:0002307)2.16810431
100Excessive salivation (HP:0003781)2.16810431
101Aplasia/Hypoplasia of the uvula (HP:0010293)2.15602723
102Type II lissencephaly (HP:0007260)2.15446045
103Male pseudohermaphroditism (HP:0000037)2.14547236
104Supranuclear gaze palsy (HP:0000605)2.14276614
105EEG with generalized epileptiform discharges (HP:0011198)2.13602134
106Abnormality of the phalanges of the 2nd finger (HP:0009541)2.11220893
107Ankyloglossia (HP:0010296)2.11083310
108Failure to thrive in infancy (HP:0001531)2.10705306
109Spinal canal stenosis (HP:0003416)2.09686228
110Mutism (HP:0002300)2.09366593
111Postaxial foot polydactyly (HP:0001830)2.07682323
112Abnormality of the phalanges of the 5th finger (HP:0004213)2.06795471
113Genital tract atresia (HP:0001827)2.06661552
114Papilledema (HP:0001085)2.06405535
115Hemiparesis (HP:0001269)2.06257666
116Pheochromocytoma (HP:0002666)2.06173070
117Bony spicule pigmentary retinopathy (HP:0007737)2.05795957
118Generalized hypotonia (HP:0001290)2.04549684
119Hypoplastic pelvis (HP:0008839)2.04268319
120Hypsarrhythmia (HP:0002521)2.03738668
121Short hallux (HP:0010109)2.02684712
122Incomplete penetrance (HP:0003829)2.02651359
123Gait imbalance (HP:0002141)2.01868688
124Congenital sensorineural hearing impairment (HP:0008527)2.01738874
125Vaginal atresia (HP:0000148)2.01409713
126Abnormality of the labia minora (HP:0012880)2.01063652
127Aplasia/Hypoplasia of the hallux (HP:0008362)2.00709899
128Fetal akinesia sequence (HP:0001989)1.98682088
129Abnormality of the lower motor neuron (HP:0002366)1.97604491
130Absent speech (HP:0001344)1.96032744
131Termporal pattern (HP:0011008)1.93358969
132Insidious onset (HP:0003587)1.93358969
133Abnormal EKG (HP:0003115)1.93091285
134Iris hypopigmentation (HP:0007730)1.92761173
135Neuroendocrine neoplasm (HP:0100634)1.92630926
136Blue irides (HP:0000635)1.91286399
137Hamartoma of the eye (HP:0010568)1.91019685
138Abnormal biliary tract physiology (HP:0012439)1.90663587
139Bile duct proliferation (HP:0001408)1.90663587
140Decreased electroretinogram (ERG) amplitude (HP:0000654)1.90653026
141Prolonged QT interval (HP:0001657)1.89454145
142Abnormality of oral frenula (HP:0000190)1.89131910
143Psychosis (HP:0000709)1.88423791
144Distal lower limb amyotrophy (HP:0008944)1.87914183
145Sleep apnea (HP:0010535)1.86870574
146Specific learning disability (HP:0001328)1.86337077
147Abnormality of macular pigmentation (HP:0008002)1.86141906
148Lower limb muscle weakness (HP:0007340)1.86095584
149Protruding tongue (HP:0010808)1.85239642
150Abnormality of saccadic eye movements (HP:0000570)1.83852437
151Abnormality of the middle phalanges of the toes (HP:0010183)1.83699711
152Congenital primary aphakia (HP:0007707)1.83513059
153Renal cortical cysts (HP:0000803)1.82778210
154Intention tremor (HP:0002080)1.82617676
155Clonus (HP:0002169)1.82086516
156Absent/shortened dynein arms (HP:0200106)1.81954850
157Dynein arm defect of respiratory motile cilia (HP:0012255)1.81954850
158Chronic hepatic failure (HP:0100626)1.81921996
159Gait ataxia (HP:0002066)1.80487088
160Preaxial hand polydactyly (HP:0001177)1.80161522
161Abnormality of DNA repair (HP:0003254)1.80089571
162Abnormality of the ileum (HP:0001549)1.79754700
163Poor suck (HP:0002033)1.79217401
164Abnormality of pain sensation (HP:0010832)1.78989655
165Impaired pain sensation (HP:0007328)1.78989655
166Stomach cancer (HP:0012126)1.78029334
167Meckel diverticulum (HP:0002245)1.77609550
168Deeply set eye (HP:0000490)1.77129483
169Congenital hepatic fibrosis (HP:0002612)1.75878778
170Large for gestational age (HP:0001520)1.75021257
171Hyperalaninemia (HP:0003348)1.74449408
172Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.74449408
173Abnormality of alanine metabolism (HP:0010916)1.74449408
174Methylmalonic aciduria (HP:0012120)1.74341628
175Abnormality of the renal collecting system (HP:0004742)1.73273963
176Postaxial hand polydactyly (HP:0001162)1.72492321
177Oligodactyly (hands) (HP:0001180)1.71691202
178Abnormal drinking behavior (HP:0030082)1.71224670
179Polydipsia (HP:0001959)1.71224670
180Intestinal atresia (HP:0011100)1.70852722
181Severe visual impairment (HP:0001141)1.70825146
182Aplasia/hypoplasia of the uterus (HP:0008684)1.70355017

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA46.51665985
2FRK4.89949429
3NTRK34.24857551
4MAP3K93.20276007
5WNK33.05316148
6CASK2.98789763
7BMPR1B2.80217293
8MAP3K122.66496960
9DAPK22.64957974
10MAP3K42.55639780
11TRIM282.52907313
12MAP4K22.49051752
13GRK12.46234401
14ACVR1B2.27652871
15MAP2K72.23858837
16NUAK12.21915112
17NTRK22.17337957
18MAP3K132.14319144
19FES2.08916427
20RIPK42.07457756
21MINK12.05287338
22KSR21.97523277
23DAPK11.97401642
24ARAF1.93488077
25ZAK1.86369292
26CAMKK11.74915605
27SIK21.74811453
28MKNK21.70286171
29TNIK1.62823189
30PRKD31.59115576
31PRPF4B1.55781610
32CDK51.54291791
33MAP2K41.52754647
34KSR11.47465375
35INSRR1.41710370
36PAK61.41355829
37ERBB31.38801484
38WNK41.35965861
39TAOK31.35196374
40CDK191.33696147
41EIF2AK31.33340315
42TLK11.32817084
43TAOK11.32014665
44MARK11.31947522
45STK391.31821867
46PLK21.26663890
47CAMKK21.26042019
48NTRK11.23563377
49TNK21.22983445
50BCR1.19354862
51GRK51.16908962
52CSNK1G21.15540669
53TYRO31.14163216
54PRKCH1.13282961
55SGK21.12733533
56PLK41.10934680
57PRKCG1.09035913
58SIK31.08513792
59CSNK1G11.07564680
60FGFR21.07481042
61SGK2231.05525460
62SGK4941.05525460
63STK38L1.02795032
64STK381.01811266
65PLK31.01504772
66RAF11.01288551
67AKT31.00621005
68CSNK1G30.99268040
69DYRK20.96510174
70ADRBK10.95953603
71SGK30.93802127
72CAMK2A0.93439515
73VRK10.93162536
74BMPR20.92182401
75WEE10.87466533
76NEK60.87424996
77CAMK2B0.86376016
78CDK180.85548277
79CSNK1A1L0.83747966
80STK110.83375623
81PHKG10.82540076
82PHKG20.82540076
83PNCK0.82128771
84OXSR10.81914154
85MAP3K20.80766744
86TXK0.80390254
87CDK150.80379070
88MAPK130.79737774
89SGK10.78872898
90MST40.78443138
91MARK20.77843199
92CCNB10.77469906
93CDK140.77179559
94UHMK10.77099784
95CAMK10.75815691
96TGFBR10.75132650
97PDK10.72748971
98CDK11A0.68021252
99TAF10.67782303
100GRK70.67054637
101EIF2AK20.65935633
102MAP3K10.64899300
103BRAF0.64059433
104MKNK10.64002944
105PTK2B0.63824744
106BCKDK0.60069487
107MUSK0.59071556
108PDPK10.58096862
109PKN10.57754938
110PINK10.56737832
111ADRBK20.55520000
112FYN0.54879804
113EIF2AK10.53333479
114CSNK1A10.51262833
115DAPK30.50481112
116ALK0.50258567
117LATS10.48717442
118TSSK60.46121728
119RPS6KA30.45874175
120GRK60.45756669
121RET0.45635777
122NME10.43811024
123FGR0.43644885
124PRKCE0.43346211
125PRKCQ0.42989066
126TEC0.42887133
127CAMK2G0.42140579
128CAMK40.41604110
129BRSK20.40860499
130MAPK70.39123043
131MAPK100.39099042
132DYRK1A0.38918473
133ERBB20.38461278
134FER0.37882244
135WNK10.37194559
136PRKCB0.37165661
137TIE10.36490774
138NLK0.36244328
139IRAK10.35077892
140CSNK1D0.34668798
141RPS6KA50.34486848
142IKBKB0.34213891
143PRKCZ0.34037439
144MOS0.33815247
145PLK10.33700642
146CDK30.33283910
147CHEK20.32846569
148PRKG10.32524537
149MAP2K10.32448085
150IGF1R0.32232929
151HCK0.31756836
152PAK30.31411820
153VRK20.31325068
154CAMK2D0.31238066
155PRKCI0.30341101
156PRKACA0.30241469
157PRKD20.30077132
158PRKCA0.29271719
159PDK40.28978314
160PDK30.28978314
161PIK3CA0.28564176

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.86720804
2Olfactory transduction_Homo sapiens_hsa047403.41647427
3Synaptic vesicle cycle_Homo sapiens_hsa047213.37024541
4GABAergic synapse_Homo sapiens_hsa047272.99776390
5Morphine addiction_Homo sapiens_hsa050322.99199296
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.76385248
7Amphetamine addiction_Homo sapiens_hsa050312.66577409
8Circadian entrainment_Homo sapiens_hsa047132.61420735
9Long-term potentiation_Homo sapiens_hsa047202.60673482
10Protein export_Homo sapiens_hsa030602.47711923
11Glutamatergic synapse_Homo sapiens_hsa047242.45117580
12Dopaminergic synapse_Homo sapiens_hsa047282.31619150
13Cocaine addiction_Homo sapiens_hsa050302.22940358
14Salivary secretion_Homo sapiens_hsa049702.06034388
15Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.05771536
16Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.04685087
17Collecting duct acid secretion_Homo sapiens_hsa049662.01509036
18Maturity onset diabetes of the young_Homo sapiens_hsa049502.00138138
19Cholinergic synapse_Homo sapiens_hsa047251.95646835
20Butanoate metabolism_Homo sapiens_hsa006501.89518913
21Renin secretion_Homo sapiens_hsa049241.88411348
22Insulin secretion_Homo sapiens_hsa049111.76325576
23Taste transduction_Homo sapiens_hsa047421.75692826
24alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.73861265
25Linoleic acid metabolism_Homo sapiens_hsa005911.73278244
26Gastric acid secretion_Homo sapiens_hsa049711.71998713
27Calcium signaling pathway_Homo sapiens_hsa040201.71584677
28Aldosterone synthesis and secretion_Homo sapiens_hsa049251.71551272
29Serotonergic synapse_Homo sapiens_hsa047261.69860311
30Oxytocin signaling pathway_Homo sapiens_hsa049211.65856269
31Fanconi anemia pathway_Homo sapiens_hsa034601.63518994
32Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.61272348
33Basal transcription factors_Homo sapiens_hsa030221.61110797
34Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.59137940
35Long-term depression_Homo sapiens_hsa047301.57728414
36Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.51992887
37Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.51640022
38Selenocompound metabolism_Homo sapiens_hsa004501.50449696
39Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.49634141
40Homologous recombination_Homo sapiens_hsa034401.42142300
41Gap junction_Homo sapiens_hsa045401.32502685
42Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.32095055
43GnRH signaling pathway_Homo sapiens_hsa049121.29760717
44cAMP signaling pathway_Homo sapiens_hsa040241.27201294
45Tryptophan metabolism_Homo sapiens_hsa003801.26448733
46Type I diabetes mellitus_Homo sapiens_hsa049401.25918805
47* Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.25424728
48Sulfur metabolism_Homo sapiens_hsa009201.24089551
49Propanoate metabolism_Homo sapiens_hsa006401.20312627
50Vibrio cholerae infection_Homo sapiens_hsa051101.20167261
51Caffeine metabolism_Homo sapiens_hsa002321.18738791
52Ether lipid metabolism_Homo sapiens_hsa005651.18445175
53Phosphatidylinositol signaling system_Homo sapiens_hsa040701.17437833
54Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.15723306
55Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.11224237
56RNA degradation_Homo sapiens_hsa030181.10405527
57Hedgehog signaling pathway_Homo sapiens_hsa043401.03908646
58Regulation of autophagy_Homo sapiens_hsa041400.98736952
59Vascular smooth muscle contraction_Homo sapiens_hsa042700.97641630
60Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.96624964
61Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.95767237
62cGMP-PKG signaling pathway_Homo sapiens_hsa040220.95742446
63Estrogen signaling pathway_Homo sapiens_hsa049150.92550006
64RNA polymerase_Homo sapiens_hsa030200.90718245
65Chemical carcinogenesis_Homo sapiens_hsa052040.90669200
66ErbB signaling pathway_Homo sapiens_hsa040120.90616977
67Phototransduction_Homo sapiens_hsa047440.90401589
68Glioma_Homo sapiens_hsa052140.90008798
69Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.89993170
70Cardiac muscle contraction_Homo sapiens_hsa042600.88884459
71Retinol metabolism_Homo sapiens_hsa008300.88135348
72Parkinsons disease_Homo sapiens_hsa050120.86312815
73Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.85504571
74Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.84943806
75Melanogenesis_Homo sapiens_hsa049160.84798366
76Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.84177103
77Type II diabetes mellitus_Homo sapiens_hsa049300.82504796
78Primary bile acid biosynthesis_Homo sapiens_hsa001200.82321164
79Steroid hormone biosynthesis_Homo sapiens_hsa001400.81619505
80Oxidative phosphorylation_Homo sapiens_hsa001900.80690184
81Axon guidance_Homo sapiens_hsa043600.76786121
82Phospholipase D signaling pathway_Homo sapiens_hsa040720.75651076
83Peroxisome_Homo sapiens_hsa041460.74514159
84Oocyte meiosis_Homo sapiens_hsa041140.73533817
85MAPK signaling pathway_Homo sapiens_hsa040100.73088644
86Glycerolipid metabolism_Homo sapiens_hsa005610.71951640
87Alzheimers disease_Homo sapiens_hsa050100.71709414
88Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.71607819
89Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.70592783
90Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.70017192
91Steroid biosynthesis_Homo sapiens_hsa001000.68430144
92Non-homologous end-joining_Homo sapiens_hsa034500.66786290
93Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.66264031
94Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.65127417
95Non-small cell lung cancer_Homo sapiens_hsa052230.64620789
96Alcoholism_Homo sapiens_hsa050340.64414668
97Dorso-ventral axis formation_Homo sapiens_hsa043200.62970346
98Pancreatic secretion_Homo sapiens_hsa049720.62063583
99Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.62019761
100Rap1 signaling pathway_Homo sapiens_hsa040150.62004684
101ABC transporters_Homo sapiens_hsa020100.61981014
102Dilated cardiomyopathy_Homo sapiens_hsa054140.60850841
103Intestinal immune network for IgA production_Homo sapiens_hsa046720.60497241
104Proteasome_Homo sapiens_hsa030500.60082746
105Thyroid hormone synthesis_Homo sapiens_hsa049180.59453364
106Basal cell carcinoma_Homo sapiens_hsa052170.59132692
107Rheumatoid arthritis_Homo sapiens_hsa053230.57368436
108Chemokine signaling pathway_Homo sapiens_hsa040620.57043888
109Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.56283914
110T cell receptor signaling pathway_Homo sapiens_hsa046600.56060680
111beta-Alanine metabolism_Homo sapiens_hsa004100.55908561
112Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.55898026
113Choline metabolism in cancer_Homo sapiens_hsa052310.55732844
114Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.54570025
115Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.54120365
116Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.54039810
117Ras signaling pathway_Homo sapiens_hsa040140.53884886
118Arachidonic acid metabolism_Homo sapiens_hsa005900.51839398
119Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.51830718
120Neurotrophin signaling pathway_Homo sapiens_hsa047220.51711276
121Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.49738209
122Inositol phosphate metabolism_Homo sapiens_hsa005620.49552966
123Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.48308465
124Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.46823332
125Mineral absorption_Homo sapiens_hsa049780.46287176
126Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.45667296
127Purine metabolism_Homo sapiens_hsa002300.44009098
128Thyroid hormone signaling pathway_Homo sapiens_hsa049190.43845585
129One carbon pool by folate_Homo sapiens_hsa006700.43702063
130VEGF signaling pathway_Homo sapiens_hsa043700.43618175
131Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.43294626
132Glucagon signaling pathway_Homo sapiens_hsa049220.42773539
133African trypanosomiasis_Homo sapiens_hsa051430.41905633
134Sphingolipid signaling pathway_Homo sapiens_hsa040710.39000532
135TGF-beta signaling pathway_Homo sapiens_hsa043500.38263965
136Vitamin digestion and absorption_Homo sapiens_hsa049770.37508411
137Metabolic pathways_Homo sapiens_hsa011000.37025819
138Endocytosis_Homo sapiens_hsa041440.35034702
139Huntingtons disease_Homo sapiens_hsa050160.34666882
140Fat digestion and absorption_Homo sapiens_hsa049750.34391874
141Hippo signaling pathway_Homo sapiens_hsa043900.32695275
142Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.32518002
143Circadian rhythm_Homo sapiens_hsa047100.32449931
144Renal cell carcinoma_Homo sapiens_hsa052110.32433054
145Ovarian steroidogenesis_Homo sapiens_hsa049130.30819056
146Platelet activation_Homo sapiens_hsa046110.30321457
147Nitrogen metabolism_Homo sapiens_hsa009100.28126453
148SNARE interactions in vesicular transport_Homo sapiens_hsa041300.26878049
149Endometrial cancer_Homo sapiens_hsa052130.26687056
150Prion diseases_Homo sapiens_hsa050200.25942484
151Longevity regulating pathway - mammal_Homo sapiens_hsa042110.25030179
152mTOR signaling pathway_Homo sapiens_hsa041500.24841810
153Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.24817710
154Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.24646618
155Wnt signaling pathway_Homo sapiens_hsa043100.23849042

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