GPX8

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1chondrocyte proliferation (GO:0035988)5.99612341
2collagen fibril organization (GO:0030199)5.98800630
3protein heterotrimerization (GO:0070208)5.37531157
4sequestering of extracellular ligand from receptor (GO:0035581)4.64255425
5bone trabecula formation (GO:0060346)4.21925696
6mesenchymal-epithelial cell signaling (GO:0060638)4.14182202
7negative regulation of chondrocyte differentiation (GO:0032331)4.00531697
8metanephric mesenchyme development (GO:0072075)3.99936831
9cartilage development involved in endochondral bone morphogenesis (GO:0060351)3.93806813
10dermatan sulfate biosynthetic process (GO:0030208)3.93562051
11keratan sulfate catabolic process (GO:0042340)3.85924731
12endodermal cell differentiation (GO:0035987)3.85270330
13kidney mesenchyme development (GO:0072074)3.81416849
14glomerular basement membrane development (GO:0032836)3.80847506
15collagen metabolic process (GO:0032963)3.76989790
16neuron projection extension involved in neuron projection guidance (GO:1902284)3.72670536
17axon extension involved in axon guidance (GO:0048846)3.72670536
18outer ear morphogenesis (GO:0042473)3.65234734
19collagen catabolic process (GO:0030574)3.64776784
20embryonic skeletal joint morphogenesis (GO:0060272)3.63924669
21chondrocyte development (GO:0002063)3.61767144
22notochord development (GO:0030903)3.60307645
23dermatan sulfate metabolic process (GO:0030205)3.59114754
24extracellular fibril organization (GO:0043206)3.56206612
25endothelial cell morphogenesis (GO:0001886)3.51512436
26multicellular organismal macromolecule metabolic process (GO:0044259)3.51361410
27regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.50828759
28cell proliferation involved in metanephros development (GO:0072203)3.50471245
29positive regulation of epithelial to mesenchymal transition (GO:0010718)3.47018620
30negative regulation of cartilage development (GO:0061037)3.42355504
31peptidyl-proline hydroxylation (GO:0019511)3.42189938
32maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.42143287
33protein retention in ER lumen (GO:0006621)3.41952525
34cell migration involved in heart development (GO:0060973)3.40195748
35positive regulation of cartilage development (GO:0061036)3.37042459
36mesenchyme morphogenesis (GO:0072132)3.36425722
37ventricular cardiac muscle cell development (GO:0055015)3.35993716
38mesenchymal cell proliferation (GO:0010463)3.35542243
39regulation of integrin-mediated signaling pathway (GO:2001044)3.34180726
40multicellular organismal catabolic process (GO:0044243)3.33536123
41multicellular organismal metabolic process (GO:0044236)3.32977368
42cell proliferation involved in kidney development (GO:0072111)3.31790576
43type B pancreatic cell proliferation (GO:0044342)3.29595634
44wound healing, spreading of epidermal cells (GO:0035313)3.29320868
45cell migration involved in sprouting angiogenesis (GO:0002042)3.26047386
46paraxial mesoderm development (GO:0048339)3.25921417
47cell adhesion mediated by integrin (GO:0033627)3.22983141
48craniofacial suture morphogenesis (GO:0097094)3.22710610
49fibril organization (GO:0097435)3.21492733
50regulation of tight junction assembly (GO:2000810)3.21221898
51negative regulation of fatty acid transport (GO:2000192)3.18532053
52substrate-dependent cell migration (GO:0006929)3.17494307
53negative regulation of axon extension involved in axon guidance (GO:0048843)3.16921336
54extracellular matrix disassembly (GO:0022617)3.16216085
55G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071993.16003511
56basement membrane organization (GO:0071711)3.15060988
57anterior/posterior axis specification, embryo (GO:0008595)3.13116628
58skin morphogenesis (GO:0043589)3.12859585
59regulation of branching involved in salivary gland morphogenesis (GO:0060693)3.12839823
60substrate adhesion-dependent cell spreading (GO:0034446)3.11639548
61neural crest cell development (GO:0014032)3.06146264
62planar cell polarity pathway involved in neural tube closure (GO:0090179)3.04229683
63regulation of cartilage development (GO:0061035)3.03576322
64positive regulation of endothelial cell apoptotic process (GO:2000353)3.03206109
65middle ear morphogenesis (GO:0042474)3.02747589
66regulation of heart morphogenesis (GO:2000826)3.02486883
67endocardial cushion morphogenesis (GO:0003203)3.02411999
68endocardial cushion development (GO:0003197)3.00799249
69epithelial to mesenchymal transition (GO:0001837)3.00474012
70embryonic cranial skeleton morphogenesis (GO:0048701)2.99683976
71positive regulation of stem cell differentiation (GO:2000738)2.98583765
72regulation of chondrocyte differentiation (GO:0032330)2.97195403
73positive regulation of extracellular matrix organization (GO:1903055)2.96929799
74hippo signaling (GO:0035329)2.96892003
75cardiac epithelial to mesenchymal transition (GO:0060317)2.95942466
76extracellular matrix organization (GO:0030198)2.93558521
77extracellular regulation of signal transduction (GO:1900115)2.93169845
78extracellular negative regulation of signal transduction (GO:1900116)2.93169845
79protein hydroxylation (GO:0018126)2.92856405
80extracellular structure organization (GO:0043062)2.92259683
81extracellular matrix assembly (GO:0085029)2.91675848
82atrioventricular valve morphogenesis (GO:0003181)2.91265721
83negative regulation of catenin import into nucleus (GO:0035414)2.90132235
84negative regulation of embryonic development (GO:0045992)2.90006700
85smooth muscle tissue development (GO:0048745)2.87751511
86cranial suture morphogenesis (GO:0060363)2.87367742
87lymphangiogenesis (GO:0001946)2.86828683
88muscle cell migration (GO:0014812)2.85610147
89positive regulation of mesenchymal cell proliferation (GO:0002053)2.85378863
90negative regulation of stem cell proliferation (GO:2000647)2.82897325
91regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.81372704
92heparan sulfate proteoglycan biosynthetic process (GO:0015012)2.80649897
93regulation of transforming growth factor beta2 production (GO:0032909)2.79597150
94wound healing, spreading of cells (GO:0044319)2.79269576
95positive regulation of osteoblast proliferation (GO:0033690)2.79153069
96regulation of mesenchymal cell proliferation (GO:0010464)2.79104151
97cellular response to vitamin D (GO:0071305)2.75427890
98organ induction (GO:0001759)2.74571467
99protein localization to cell surface (GO:0034394)2.73089812
100heart valve morphogenesis (GO:0003179)2.72388438
101cellular response to vitamin (GO:0071295)2.71395563
102regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.70597287
103mesenchymal cell development (GO:0014031)2.69640428
104epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)2.69510370
105retina vasculature morphogenesis in camera-type eye (GO:0061299)2.69499727
106glomerulus development (GO:0032835)2.68840898
107convergent extension (GO:0060026)2.68708279
108mesonephric tubule development (GO:0072164)2.67334990
109negative regulation of axon guidance (GO:1902668)2.67231446
110mesenchyme development (GO:0060485)2.66602127
111mesodermal cell differentiation (GO:0048333)2.65731515
112Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.65180464
113Golgi transport vesicle coating (GO:0048200)2.65129261
114COPI coating of Golgi vesicle (GO:0048205)2.65129261
115negative regulation of BMP signaling pathway (GO:0030514)2.62567674
116artery development (GO:0060840)2.60212679
117establishment of integrated proviral latency (GO:0075713)2.58630630
118regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.55774656
119negative regulation of fibroblast growth factor receptor signaling pathway (GO:0040037)2.54599020
120regulation of establishment of planar polarity (GO:0090175)2.52582048
121proteasome assembly (GO:0043248)2.51761331
122mitotic metaphase plate congression (GO:0007080)2.51637898
123blood vessel maturation (GO:0001955)2.50520294
124positive regulation of SMAD protein import into nucleus (GO:0060391)2.49085676
125vascular endothelial growth factor signaling pathway (GO:0038084)2.48420199
126sprouting angiogenesis (GO:0002040)2.47217647
127establishment of planar polarity (GO:0001736)2.45893742
128establishment of tissue polarity (GO:0007164)2.45893742
129negative regulation of cardiac muscle tissue development (GO:0055026)2.45843166
130pericardium development (GO:0060039)2.45580802
131regulation of cell fate specification (GO:0042659)2.44328649
132CENP-A containing nucleosome assembly (GO:0034080)2.43472439
133cochlea morphogenesis (GO:0090103)2.42136750
134negative chemotaxis (GO:0050919)2.41805814
135chromatin remodeling at centromere (GO:0031055)2.39254042
136establishment of apical/basal cell polarity (GO:0035089)2.38615372
137protein localization to kinetochore (GO:0034501)2.36947086
138regulation of cardioblast differentiation (GO:0051890)2.36059773

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRIM28_21343339_ChIP-Seq_HEK293_Human7.80309304
2TP63_17297297_ChIP-ChIP_HaCaT_Human5.25623416
3RARG_19884340_ChIP-ChIP_MEFs_Mouse4.85643957
4PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse3.78147922
5TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.67090984
6RBPJ_22232070_ChIP-Seq_NCS_Mouse3.50456596
7CLOCK_20551151_ChIP-Seq_293T_Human3.26811657
8WT1_19549856_ChIP-ChIP_CCG9911_Human3.19240004
9CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse2.93264543
10E2F7_22180533_ChIP-Seq_HELA_Human2.72038122
11CJUN_26792858_Chip-Seq_BT549_Human2.70494509
12RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.59450035
13FOXM1_23109430_ChIP-Seq_U2OS_Human2.49392326
14ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.45372901
15EP300_21415370_ChIP-Seq_HL-1_Mouse2.43327877
16HIF1A_21447827_ChIP-Seq_MCF-7_Human2.43138123
17TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.32487164
18BRD4_25478319_ChIP-Seq_HGPS_Human2.27584730
19CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse2.24765674
20HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.19684026
21TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.13657709
22NFE2L2_20460467_ChIP-Seq_MEFs_Mouse2.12826817
23NRF2_20460467_ChIP-Seq_MEFs_Mouse2.12826817
24SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.12629754
25KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.07372889
26CHD7_19251738_ChIP-ChIP_MESCs_Mouse2.04608713
27EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.03450827
28MYC_18555785_ChIP-Seq_MESCs_Mouse1.97985376
29ESR1_21235772_ChIP-Seq_MCF-7_Human1.95465217
30EED_16625203_ChIP-ChIP_MESCs_Mouse1.94850078
31NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.93577958
32POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.93307681
33SALL4_18804426_ChIP-ChIP_XEN_Mouse1.86147112
34TP53_18474530_ChIP-ChIP_U2OS_Human1.86129583
35PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.83318714
36GABP_17652178_ChIP-ChIP_JURKAT_Human1.81721331
37TP53_20018659_ChIP-ChIP_R1E_Mouse1.81464565
38WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.80809738
39FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.79677307
40E2F4_17652178_ChIP-ChIP_JURKAT_Human1.78255128
41SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.76672802
42SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.76672802
43CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.72855699
44MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.67904387
45CDX2_19796622_ChIP-Seq_MESCs_Mouse1.67484944
46HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.65701804
47PPAR_26484153_Chip-Seq_NCI-H1993_Human1.63353558
48SOX2_20726797_ChIP-Seq_SW620_Human1.55540037
49* ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.49125164
50SMAD_19615063_ChIP-ChIP_OVARY_Human1.47733738
51RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.47664821
52NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.46276043
53AR_21909140_ChIP-Seq_LNCAP_Human1.45832152
54JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.45211022
55TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.44577511
56NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.42930034
57KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.42441864
58PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.41093824
59TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.40403949
60CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.39937896
61EWS_26573619_Chip-Seq_HEK293_Human1.33135147
62MYC_19079543_ChIP-ChIP_MESCs_Mouse1.30802110
63JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.29935436
64FUS_26573619_Chip-Seq_HEK293_Human1.29674675
65CREB1_15753290_ChIP-ChIP_HEK293T_Human1.29499790
66E2F1_18555785_ChIP-Seq_MESCs_Mouse1.29466155
67ISL1_27105846_Chip-Seq_CPCs_Mouse1.28515245
68UBF1/2_26484160_Chip-Seq_HMECs_Human1.28050267
69RNF2_18974828_ChIP-Seq_MESCs_Mouse1.28032736
70EZH2_18974828_ChIP-Seq_MESCs_Mouse1.28032736
71TBX3_20139965_ChIP-Seq_ESCs_Mouse1.27930229
72SALL1_21062744_ChIP-ChIP_HESCs_Human1.27521404
73SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.27363085
74SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.26852980
75* SMC1_22415368_ChIP-Seq_MEFs_Mouse1.26828587
76TBX3_20139965_ChIP-Seq_MESCs_Mouse1.26390507
77ESR1_20079471_ChIP-ChIP_T-47D_Human1.26219961
78ELK1_22589737_ChIP-Seq_MCF10A_Human1.25973053
79ZNF217_24962896_ChIP-Seq_MCF-7_Human1.23364704
80SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.22705720
81NELFA_20434984_ChIP-Seq_ESCs_Mouse1.21488457
82MYC_19030024_ChIP-ChIP_MESCs_Mouse1.21254540
83ZFP57_27257070_Chip-Seq_ESCs_Mouse1.19198478
84SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.17869572
85SOX2_18555785_ChIP-Seq_MESCs_Mouse1.12980077
86FLI1_27457419_Chip-Seq_LIVER_Mouse1.12967250
87MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.11168119
88POU5F1_16153702_ChIP-ChIP_HESCs_Human1.11058107
89NANOG_16153702_ChIP-ChIP_HESCs_Human1.10531521
90GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.09945915
91SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.09628146
92* SA1_22415368_ChIP-Seq_MEFs_Mouse1.09285215
93MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.08989067
94SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.08325457
95TBX20_22328084_ChIP-Seq_HEART_Mouse1.08061072
96TBX20_22080862_ChIP-Seq_HEART_Mouse1.08061072
97SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.07653720
98ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.06919603
99EOMES_21245162_ChIP-Seq_HESCs_Human1.06605573
100PCGF2_27294783_Chip-Seq_ESCs_Mouse1.06198437
101SOX2_16153702_ChIP-ChIP_HESCs_Human1.05890841
102ELK1_19687146_ChIP-ChIP_HELA_Human1.05329093
103NFI_21473784_ChIP-Seq_ESCs_Mouse1.05120897
104ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.03765920
105FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.03689076
106TP63_19390658_ChIP-ChIP_HaCaT_Human1.03686500
107P300_19829295_ChIP-Seq_ESCs_Human1.03473635
108SOX9_24532713_ChIP-Seq_HFSC_Mouse1.02503424
109ESR2_21235772_ChIP-Seq_MCF-7_Human1.01804860
110KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.01556466
111KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.01556466
112KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.01556466
113SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.01506044
114* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.00660518
115PIAS1_25552417_ChIP-Seq_VCAP_Human1.00268696
116EST1_17652178_ChIP-ChIP_JURKAT_Human0.99354618
117TP53_16413492_ChIP-PET_HCT116_Human0.99068625
118EGR1_19374776_ChIP-ChIP_THP-1_Human0.98913958
119HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.98266044
120PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.97695890
121TCF4_18268006_ChIP-ChIP_LS174T_Human0.96910463
122GATA4_21415370_ChIP-Seq_HL-1_Mouse0.96711976
123PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.96121346
124EZH2_27304074_Chip-Seq_ESCs_Mouse0.95948145
125EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.95205212
126PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.95035198
127PADI4_21655091_ChIP-ChIP_MCF-7_Human0.94092721
128OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.93912795
129TCF3_18692474_ChIP-Seq_MESCs_Mouse0.92373712
130PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.91840748
131DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.91413685
132TCF3_18692474_ChIP-Seq_MEFs_Mouse0.91275901
133ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.90944414
134MYCN_18555785_ChIP-Seq_MESCs_Mouse0.90874009
135TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.90179441
136TP53_23651856_ChIP-Seq_MEFs_Mouse0.88040639
137* SMC3_22415368_ChIP-Seq_MEFs_Mouse0.87950239
138P300_27058665_Chip-Seq_ZR-75-30cells_Human0.87249458
139RXR_22108803_ChIP-Seq_LS180_Human0.85339090
140ELK3_25401928_ChIP-Seq_HUVEC_Human0.85306738
141SOX17_20123909_ChIP-Seq_XEN_Mouse0.84988257
142JARID2_20075857_ChIP-Seq_MESCs_Mouse0.83469567
143KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.82329538
144UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.81618050

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen6.85541997
2MP0005503_abnormal_tendon_morphology5.42553708
3MP0005275_abnormal_skin_tensile4.45844267
4MP0003279_aneurysm3.40820499
5MP0003705_abnormal_hypodermis_morpholog3.14644960
6MP0004272_abnormal_basement_membrane3.10268306
7MP0010030_abnormal_orbit_morphology2.95224149
8MP0001958_emphysema2.85078077
9MP0009384_cardiac_valve_regurgitation2.81270043
10MP0009250_abnormal_appendicular_skeleto2.40421339
11MP0005508_abnormal_skeleton_morphology2.33638762
12MP0005623_abnormal_meninges_morphology2.26103856
13MP0006054_spinal_hemorrhage2.14781425
14MP0003385_abnormal_body_wall2.05215701
15MP0010368_abnormal_lymphatic_system2.00961236
16MP0002282_abnormal_trachea_morphology2.00255479
17MP0001542_abnormal_bone_strength1.90995334
18MP0003942_abnormal_urinary_system1.87758060
19MP0009053_abnormal_anal_canal1.72611019
20MP0005023_abnormal_wound_healing1.69145570
21MP0001879_abnormal_lymphatic_vessel1.68922008
22MP0004134_abnormal_chest_morphology1.68384405
23MP0002108_abnormal_muscle_morphology1.67123109
24MP0003566_abnormal_cell_adhesion1.63417742
25MP0000163_abnormal_cartilage_morphology1.59944399
26MP0002295_abnormal_pulmonary_circulatio1.57388253
27MP0003941_abnormal_skin_development1.54635522
28MP0002896_abnormal_bone_mineralization1.52053252
29MP0002060_abnormal_skin_morphology1.52013829
30MP0000049_abnormal_middle_ear1.47296402
31MP0005171_absent_coat_pigmentation1.47127083
32MP0002115_abnormal_skeleton_extremities1.44587597
33MP0000534_abnormal_ureter_morphology1.43587337
34MP0001299_abnormal_eye_distance/1.43355117
35MP0000537_abnormal_urethra_morphology1.43230326
36MP0000767_abnormal_smooth_muscle1.35263276
37MP0003115_abnormal_respiratory_system1.34280496
38MP0005257_abnormal_intraocular_pressure1.32926647
39MP0002932_abnormal_joint_morphology1.31326731
40MP0003937_abnormal_limbs/digits/tail_de1.29456335
41MP0003755_abnormal_palate_morphology1.29329323
42MP0002249_abnormal_larynx_morphology1.28124690
43MP0000428_abnormal_craniofacial_morphol1.27438336
44MP0000733_abnormal_muscle_development1.26149098
45MP0003091_abnormal_cell_migration1.26146755
46MP0000762_abnormal_tongue_morphology1.25897196
47MP0002113_abnormal_skeleton_development1.22520617
48MP0010352_gastrointestinal_tract_polyps1.19987195
49MP0005390_skeleton_phenotype1.18513126
50MP0008932_abnormal_embryonic_tissue1.17822539
51MP0003122_maternal_imprinting1.17636015
52MP0002933_joint_inflammation1.16885904
53MP0005248_abnormal_Harderian_gland1.16681824
54MP0009780_abnormal_chondrocyte_physiolo1.16582939
55MP0002938_white_spotting1.15667263
56MP0002109_abnormal_limb_morphology1.14217149
57MP0001243_abnormal_dermal_layer1.12735501
58MP0004084_abnormal_cardiac_muscle1.12277179
59MP0001293_anophthalmia1.11878802
60MP0003123_paternal_imprinting1.09729260
61MP0002697_abnormal_eye_size1.06276275
62MP0000749_muscle_degeneration1.05279676
63MP0003935_abnormal_craniofacial_develop1.04769085
64MP0000750_abnormal_muscle_regeneration1.03209776
65MP0002116_abnormal_craniofacial_bone1.02824972
66MP0000432_abnormal_head_morphology1.01257456
67MP0004957_abnormal_blastocyst_morpholog1.01100496
68MP0002233_abnormal_nose_morphology1.00864398
69MP0003283_abnormal_digestive_organ0.99759240
70MP0003950_abnormal_plasma_membrane0.97394892
71MP0002254_reproductive_system_inflammat0.96586566
72MP0000516_abnormal_urinary_system0.94915672
73MP0005367_renal/urinary_system_phenotyp0.94915672
74MP0002089_abnormal_postnatal_growth/wei0.90618682
75MP0005595_abnormal_vascular_smooth0.90559220
76MP0001286_abnormal_eye_development0.90189829
77MP0008007_abnormal_cellular_replicative0.88473414
78MP0002111_abnormal_tail_morphology0.88298844
79MP0002085_abnormal_embryonic_tissue0.87276422
80MP0002128_abnormal_blood_circulation0.87115120
81MP0009697_abnormal_copulation0.85558173
82MP0000566_synostosis0.85366732
83MP0002084_abnormal_developmental_patter0.83979201
84MP0006138_congestive_heart_failure0.83297975
85MP0000751_myopathy0.82367379
86MP0005388_respiratory_system_phenotype0.82270679
87MP0002133_abnormal_respiratory_system0.82270679
88MP0001177_atelectasis0.80367005
89MP0005164_abnormal_response_to0.80030561
90MP0001614_abnormal_blood_vessel0.80013917
91MP0001175_abnormal_lung_morphology0.79880261
92MP0002177_abnormal_outer_ear0.78911239
93MP0009379_abnormal_foot_pigmentation0.78846467
94MP0002114_abnormal_axial_skeleton0.78668104
95MP0000013_abnormal_adipose_tissue0.78459883
96MP0001849_ear_inflammation0.78096986
97MP0003795_abnormal_bone_structure0.77686090
98MP0002998_abnormal_bone_remodeling0.77333088
99MP0004883_abnormal_blood_vessel0.76498229
100MP0004233_abnormal_muscle_weight0.74277599
101MP0002925_abnormal_cardiovascular_devel0.73558490
102MP0002102_abnormal_ear_morphology0.71766590
103MP0002092_abnormal_eye_morphology0.71649540
104MP0002168_other_aberrant_phenotype0.69187306
105MP0000462_abnormal_digestive_system0.69024489
106MP0003119_abnormal_digestive_system0.68823165
107MP0010386_abnormal_urinary_bladder0.68788295
108MP0005197_abnormal_uvea_morphology0.68303618
109MP0002972_abnormal_cardiac_muscle0.68258503
110MP0004197_abnormal_fetal_growth/weight/0.68078754
111MP0008775_abnormal_heart_ventricle0.67035183
112MP0002877_abnormal_melanocyte_morpholog0.66950065
113MP0005193_abnormal_anterior_eye0.66778155
114MP0004858_abnormal_nervous_system0.66189774
115MP0003111_abnormal_nucleus_morphology0.65884122
116MP0004087_abnormal_muscle_fiber0.64813174
117MP0003121_genomic_imprinting0.64163525
118MP0000467_abnormal_esophagus_morphology0.62738627
119MP0001915_intracranial_hemorrhage0.62512617
120MP0005620_abnormal_muscle_contractility0.62497857
121MP0010630_abnormal_cardiac_muscle0.62319006
122MP0003077_abnormal_cell_cycle0.62066890
123MP0003186_abnormal_redox_activity0.59288540
124MP0002234_abnormal_pharynx_morphology0.59283708
125MP0001348_abnormal_lacrimal_gland0.58884897
126MP0001661_extended_life_span0.58017902
127MP0004133_heterotaxia0.57377774

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)6.99002740
2Premature rupture of membranes (HP:0001788)6.32609932
3Neonatal short-limb short stature (HP:0008921)4.34363239
4Aortic dissection (HP:0002647)4.25842880
5Abnormality of dentin (HP:0010299)4.11009555
6Soft skin (HP:0000977)4.03231959
7Aortic aneurysm (HP:0004942)4.03142493
8Shallow orbits (HP:0000586)3.67467350
9Atrophic scars (HP:0001075)3.62380568
10Ankle contracture (HP:0006466)3.57660629
11Wormian bones (HP:0002645)3.51682880
12Spinal rigidity (HP:0003306)3.48702457
13Cervical subluxation (HP:0003308)3.46806201
14Biconcave vertebral bodies (HP:0004586)3.35041027
15Broad metatarsal (HP:0001783)3.26473127
16Vascular tortuosity (HP:0004948)3.24390021
17Type 1 muscle fiber predominance (HP:0003803)3.15394536
18Bladder diverticulum (HP:0000015)3.03630413
19Blue sclerae (HP:0000592)3.00233342
20Vertebral compression fractures (HP:0002953)2.98597634
21Follicular hyperkeratosis (HP:0007502)2.94236931
22Dilatation of the ascending aorta (HP:0005111)2.91885713
23Mesomelia (HP:0003027)2.84925922
24Arterial tortuosity (HP:0005116)2.80523147
25Cerebral aneurysm (HP:0004944)2.74820765
26Fragile skin (HP:0001030)2.73311566
27Cupped ribs (HP:0000887)2.60483298
28Peritonitis (HP:0002586)2.60296757
29Epiphyseal dysplasia (HP:0002656)2.59794734
30Wide anterior fontanel (HP:0000260)2.47137313
31Overgrowth (HP:0001548)2.41651254
32Bell-shaped thorax (HP:0001591)2.37581644
33Abnormality of the acetabulum (HP:0003170)2.33966466
34Coronal craniosynostosis (HP:0004440)2.30805225
35Mitral valve prolapse (HP:0001634)2.28532704
36Osteoarthritis (HP:0002758)2.27417844
37Hepatoblastoma (HP:0002884)2.27317389
38Hypoplastic ischia (HP:0003175)2.25714413
39Wrist flexion contracture (HP:0001239)2.24794776
40Aortic regurgitation (HP:0001659)2.24738728
41Spinal cord lesions (HP:0100561)2.24291743
42Syringomyelia (HP:0003396)2.24291743
43Genu recurvatum (HP:0002816)2.23788684
44Short nail (HP:0001799)2.23108457
45Mild short stature (HP:0003502)2.22219352
46Aortic valve stenosis (HP:0001650)2.21843781
47Coxa vara (HP:0002812)2.18126793
48Ectopia lentis (HP:0001083)2.17763043
49Hyperextensible skin (HP:0000974)2.16930320
50Mildly elevated creatine phosphokinase (HP:0008180)2.16311415
51Increased connective tissue (HP:0009025)2.15286037
52Broad long bones (HP:0005622)2.14682923
53Spondylolisthesis (HP:0003302)2.14077242
54Slender build (HP:0001533)2.13919979
55Breech presentation (HP:0001623)2.13770567
56Short hallux (HP:0010109)2.13658057
57Platyspondyly (HP:0000926)2.13345228
58Joint laxity (HP:0001388)2.10090663
59Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.09796410
60Abnormality of the ischium (HP:0003174)2.07902806
61Abnormal delivery (HP:0001787)2.05217710
62Tarsal synostosis (HP:0008368)2.02212179
63Elbow flexion contracture (HP:0002987)2.01220624
64Abnormality of the umbilical cord (HP:0010881)1.99589902
65Morphological abnormality of the middle ear (HP:0008609)1.99431512
66Abnormality of the 2nd finger (HP:0004100)1.98794349
67Osteolytic defects of the phalanges of the hand (HP:0009771)1.95945846
68Osteolytic defects of the hand bones (HP:0009699)1.95945846
69Hip contracture (HP:0003273)1.95429522
70Femoral bowing (HP:0002980)1.94150034
71Pterygium (HP:0001059)1.92886157
72Delayed gross motor development (HP:0002194)1.92670519
73Ulnar bowing (HP:0003031)1.92410902
74Vitreoretinal degeneration (HP:0000655)1.92336211
75Renal duplication (HP:0000075)1.92196121
76Aplasia/Hypoplasia of the hallux (HP:0008362)1.91502819
77Aplasia involving bones of the extremities (HP:0009825)1.90879695
78Aplasia involving bones of the upper limbs (HP:0009823)1.90879695
79Aplasia of the phalanges of the hand (HP:0009802)1.90879695
80Subacute progressive viral hepatitis (HP:0006572)1.90346049
81Deformed tarsal bones (HP:0008119)1.89371804
82Deviation of the hallux (HP:0010051)1.89185681
83Abnormality of carpal bone ossification (HP:0006257)1.88965527
84Redundant skin (HP:0001582)1.87890903
85Knee flexion contracture (HP:0006380)1.87203029
86Broad toe (HP:0001837)1.86924139
87Nonimmune hydrops fetalis (HP:0001790)1.85240267
88Buphthalmos (HP:0000557)1.85097780
89Asymmetry of the thorax (HP:0001555)1.84988883
90Limited hip movement (HP:0008800)1.84964547
91Metaphyseal dysplasia (HP:0100255)1.83370752
92Spinal cord compression (HP:0002176)1.83200627
93Increased corneal curvature (HP:0100692)1.82800698
94Keratoconus (HP:0000563)1.82800698
95Single umbilical artery (HP:0001195)1.82572277
96Abnormality of the fetal cardiovascular system (HP:0010948)1.82572277
97Abnormal umbilical cord blood vessels (HP:0011403)1.82572277
98Broad ribs (HP:0000885)1.82534383
99Protruding ear (HP:0000411)1.82259833
100Calcaneovalgus deformity (HP:0001848)1.81576133
101Inguinal hernia (HP:0000023)1.81139580
102Synostosis involving bones of the lower limbs (HP:0009138)1.80786799
103Synostosis involving bones of the feet (HP:0009140)1.80786799
104Broad phalanx (HP:0006009)1.80778981
105Camptodactyly of toe (HP:0001836)1.80666506
106Delayed cranial suture closure (HP:0000270)1.79949046
107Beaking of vertebral bodies (HP:0004568)1.79560857
108Short middle phalanx of the 5th finger (HP:0004220)1.78866713
109Infantile muscular hypotonia (HP:0008947)1.78695077
110Microglossia (HP:0000171)1.77570116
111Osteopenia (HP:0000938)1.77110646
112Decreased skull ossification (HP:0004331)1.76680985
113Scapular winging (HP:0003691)1.76640356
114Pulmonary artery stenosis (HP:0004415)1.76543795
115Tibial bowing (HP:0002982)1.75523826
116Mitral regurgitation (HP:0001653)1.75438812
117Abnormal ossification of hand bones (HP:0005921)1.74849427
118Bifid tongue (HP:0010297)1.74797396
119Generalized amyotrophy (HP:0003700)1.74719750
120Hallux valgus (HP:0001822)1.74614584
121Bowel diverticulosis (HP:0005222)1.73592047
122Abnormality of the phalanges of the 2nd finger (HP:0009541)1.73098649
123Round ear (HP:0100830)1.72843413
124Absent frontal sinuses (HP:0002688)1.72819969
125Natal tooth (HP:0000695)1.71416906
126Cardiovascular calcification (HP:0011915)1.71031219
127Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.69057203
128Disproportionate tall stature (HP:0001519)1.65184710
129Delayed closure of the anterior fontanelle (HP:0001476)1.63752272
130Hypoventilation (HP:0002791)1.63030307
131Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)1.61888836
132Hypoplasia of the iris (HP:0007676)1.61780874
133Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.58876680
134Abnormality of the phalanges of the hallux (HP:0010057)1.57330584
135Joint stiffness (HP:0001387)1.56754538
136Mitral stenosis (HP:0001718)1.56269049
137Partial duplication of the phalanx of hand (HP:0009999)1.55155325

Predicted kinase interactions (KEA)

RankGene SetZ-score
1DDR24.84318417
2LATS23.09603449
3EPHB23.01567270
4ERBB32.92353791
5LATS12.92121219
6TESK12.81198782
7TTN2.77343142
8LIMK12.71816593
9PDGFRA2.71357182
10BUB12.61853068
11STK38L2.59027907
12MYLK2.57988791
13TRIB32.51369913
14NEK12.29669255
15TRPM72.26681967
16FRK1.92367314
17ZAK1.92261047
18PAK21.91954418
19FER1.91463330
20NTRK11.86816195
21TTK1.82746408
22VRK21.80173750
23PIK3CA1.76203258
24FLT31.70899038
25ROCK11.54725935
26ILK1.48660018
27SIK11.46191676
28RPS6KA41.45842824
29FGFR11.42480512
30NEK91.41662867
31STK31.41015290
32PAK31.40716726
33EPHA31.40524741
34LRRK21.40292997
35PKN21.40166239
36PLK21.38624981
37PIM21.38290562
38TGFBR21.36464729
39TGFBR11.35636236
40MKNK11.35064697
41WEE11.34953116
42MAP3K31.34604019
43EIF2AK31.29294967
44CDC71.28518862
45MAP3K121.26790005
46TAF11.23080182
47PTK2B1.20951716
48MET1.20877698
49STK241.19950848
50MUSK1.17485431
51NUAK11.15779586
52NME21.13196653
53TRIM281.12581949
54MOS1.12408948
55PLK41.11375235
56NEK21.07856391
57PTK21.07331184
58PAK41.04333500
59TSSK61.04214639
60BRSK11.04100739
61SRPK11.02595138
62PLK10.99810232
63GRK10.99008616
64PNCK0.98353123
65PIK3CG0.97618704
66TNIK0.97137375
67DMPK0.96090858
68AKT30.92469079
69ERN10.91506185
70OBSCN0.89784397
71STK160.86791254
72ROCK20.86736462
73EPHA20.86136131
74BMX0.85282361
75FGFR20.82438663
76PDGFRB0.80829778
77MST40.80809039
78CHEK20.77562895
79PLK30.77040092
80PRKG20.74533693
81PTK60.72692357
82MAP2K10.71406634
83PRKD30.69377002
84TAOK20.67418394
85RIPK10.66546193
86EIF2AK10.66324450
87LMTK20.64323381
88CDK80.63049152
89BRSK20.62083003
90PDK20.61264801
91BCR0.60054813
92MKNK20.57885775
93PAK10.54721816
94CDC42BPA0.53405927
95VRK10.52336204
96PRKD20.52323278
97INSR0.50187870
98STK380.49103421
99KDR0.47738234
100WNK10.45529938
101MST1R0.45436484
102CDK60.44980774
103STK100.44879751
104PRKD10.43969468
105STK40.43304561
106DYRK30.40841901
107PAK60.40604950
108AURKB0.39993299
109PBK0.39622365
110MTOR0.37813699
111CSNK1G10.37608061
112AURKA0.37167874
113EIF2AK20.37119218
114IGF1R0.35196790
115BRAF0.35005908
116BMPR1B0.34092068
117DAPK30.33057858
118PRKCE0.31844522
119MELK0.31191853
120ERBB20.31167951
121GRK70.30629892
122ADRBK10.30453398
123ERBB40.30306237
124CHEK10.29904480
125WNK30.29574917
126TESK20.29172684
127MAPKAPK20.28366283
128SRC0.27925780
129CDK70.27766519
130RPS6KB20.26134261
131DYRK1B0.26061789
132NEK60.25773751
133CDK140.25298068
134GSK3A0.21968325
135FGFR30.20889837
136MAP3K80.20540085
137TIE10.20027463
138ABL20.19321167

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045124.61166492
2Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005323.31465983
3Focal adhesion_Homo sapiens_hsa045103.19877277
4TGF-beta signaling pathway_Homo sapiens_hsa043502.88622964
5Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054102.68506708
6Hippo signaling pathway_Homo sapiens_hsa043902.63797734
7Protein digestion and absorption_Homo sapiens_hsa049742.53179012
8Adherens junction_Homo sapiens_hsa045202.51573051
9Basal cell carcinoma_Homo sapiens_hsa052172.49123725
10Proteoglycans in cancer_Homo sapiens_hsa052052.47823966
11Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.41500459
12Dilated cardiomyopathy_Homo sapiens_hsa054142.39964055
13Bacterial invasion of epithelial cells_Homo sapiens_hsa051002.02231830
14Hedgehog signaling pathway_Homo sapiens_hsa043401.94969705
15Malaria_Homo sapiens_hsa051441.93771731
16Small cell lung cancer_Homo sapiens_hsa052221.86098640
17Mismatch repair_Homo sapiens_hsa034301.84744844
18One carbon pool by folate_Homo sapiens_hsa006701.81658943
19Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.81471212
20PI3K-Akt signaling pathway_Homo sapiens_hsa041511.81055931
21AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.79181048
22MicroRNAs in cancer_Homo sapiens_hsa052061.75151764
23Bladder cancer_Homo sapiens_hsa052191.71508570
24Non-homologous end-joining_Homo sapiens_hsa034501.65792210
25Amoebiasis_Homo sapiens_hsa051461.57132406
26RNA polymerase_Homo sapiens_hsa030201.55908925
27DNA replication_Homo sapiens_hsa030301.53733553
28Tight junction_Homo sapiens_hsa045301.51752059
29Melanoma_Homo sapiens_hsa052181.48951333
30Protein export_Homo sapiens_hsa030601.47781626
31Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.44235747
32Basal transcription factors_Homo sapiens_hsa030221.40762581
33Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.39344769
34Viral myocarditis_Homo sapiens_hsa054161.38894743
35Selenocompound metabolism_Homo sapiens_hsa004501.38412963
36Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.37061192
37Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.34759648
38p53 signaling pathway_Homo sapiens_hsa041151.34603935
39Wnt signaling pathway_Homo sapiens_hsa043101.32197386
40Vitamin B6 metabolism_Homo sapiens_hsa007501.29169627
41Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.29131628
42Regulation of actin cytoskeleton_Homo sapiens_hsa048101.22786239
43Pathways in cancer_Homo sapiens_hsa052001.22531822
44Sulfur metabolism_Homo sapiens_hsa009201.20463195
45Prostate cancer_Homo sapiens_hsa052151.18904893
46Homologous recombination_Homo sapiens_hsa034401.16554511
47Leukocyte transendothelial migration_Homo sapiens_hsa046701.12985598
48Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.11929010
49Pyrimidine metabolism_Homo sapiens_hsa002401.10687260
50Cell cycle_Homo sapiens_hsa041101.09748312
51Fanconi anemia pathway_Homo sapiens_hsa034601.04288770
52Axon guidance_Homo sapiens_hsa043601.02620377
53HTLV-I infection_Homo sapiens_hsa051661.02463564
54N-Glycan biosynthesis_Homo sapiens_hsa005101.01048536
55Steroid biosynthesis_Homo sapiens_hsa001001.00687997
56Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.00014533
57Cysteine and methionine metabolism_Homo sapiens_hsa002700.99465036
58Rap1 signaling pathway_Homo sapiens_hsa040150.96931984
59Fatty acid elongation_Homo sapiens_hsa000620.95085808
60Folate biosynthesis_Homo sapiens_hsa007900.92337603
61Melanogenesis_Homo sapiens_hsa049160.89659962
62Pyruvate metabolism_Homo sapiens_hsa006200.89647820
63Chronic myeloid leukemia_Homo sapiens_hsa052200.88278435
64Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.88032997
65Biosynthesis of amino acids_Homo sapiens_hsa012300.82465851
662-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.75320085
67Base excision repair_Homo sapiens_hsa034100.75031974
68Endometrial cancer_Homo sapiens_hsa052130.74454428
69HIF-1 signaling pathway_Homo sapiens_hsa040660.73719025
70Shigellosis_Homo sapiens_hsa051310.73653094
71Proteasome_Homo sapiens_hsa030500.73363199
72Colorectal cancer_Homo sapiens_hsa052100.71773710
73Purine metabolism_Homo sapiens_hsa002300.71400943
74* Glutathione metabolism_Homo sapiens_hsa004800.69968360
75RNA degradation_Homo sapiens_hsa030180.69730584
76Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.69058166
77Spliceosome_Homo sapiens_hsa030400.68046159
78Thyroid cancer_Homo sapiens_hsa052160.66612009
79Central carbon metabolism in cancer_Homo sapiens_hsa052300.65520707
80Pancreatic cancer_Homo sapiens_hsa052120.65366488
81Ovarian steroidogenesis_Homo sapiens_hsa049130.65115670
82Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.63263828
83Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.60675653
84Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.60121473
85Platelet activation_Homo sapiens_hsa046110.60023928
86Phagosome_Homo sapiens_hsa041450.59852020
87Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.57611857
88Gap junction_Homo sapiens_hsa045400.57122548
89Cardiac muscle contraction_Homo sapiens_hsa042600.56388591
90Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.55900570
91Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.55258509
92Ribosome_Homo sapiens_hsa030100.55122519
93Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.54694852
94TNF signaling pathway_Homo sapiens_hsa046680.54103365
95Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.52894030
96Parkinsons disease_Homo sapiens_hsa050120.50907279
97Vascular smooth muscle contraction_Homo sapiens_hsa042700.50665957
98Glycosaminoglycan degradation_Homo sapiens_hsa005310.47825717
99Glioma_Homo sapiens_hsa052140.46546518
100Viral carcinogenesis_Homo sapiens_hsa052030.46259679
101* Arachidonic acid metabolism_Homo sapiens_hsa005900.45431062
102Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.45223793
103Oxidative phosphorylation_Homo sapiens_hsa001900.45108754
104Renin-angiotensin system_Homo sapiens_hsa046140.44810407
105Alzheimers disease_Homo sapiens_hsa050100.44159789
106RNA transport_Homo sapiens_hsa030130.44106018
107Carbon metabolism_Homo sapiens_hsa012000.43489518
108Toxoplasmosis_Homo sapiens_hsa051450.42749639
109Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.42639095
110Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.42617677
111Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.42538067
112Hepatitis B_Homo sapiens_hsa051610.39988297
113cGMP-PKG signaling pathway_Homo sapiens_hsa040220.39472537
114Mineral absorption_Homo sapiens_hsa049780.38873132
115Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.38561928
116Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.37990536
117Apoptosis_Homo sapiens_hsa042100.37264461
118Ras signaling pathway_Homo sapiens_hsa040140.36845359
119Oocyte meiosis_Homo sapiens_hsa041140.36833412
120Chemical carcinogenesis_Homo sapiens_hsa052040.36097423
121* Thyroid hormone synthesis_Homo sapiens_hsa049180.35013858
122Metabolic pathways_Homo sapiens_hsa011000.34734204
123Renal cell carcinoma_Homo sapiens_hsa052110.34360493
124Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.33304543
125Notch signaling pathway_Homo sapiens_hsa043300.32388481
126Sphingolipid metabolism_Homo sapiens_hsa006000.30631464
127Thyroid hormone signaling pathway_Homo sapiens_hsa049190.29584491
128FoxO signaling pathway_Homo sapiens_hsa040680.28253870
129Nucleotide excision repair_Homo sapiens_hsa034200.26695787
130Galactose metabolism_Homo sapiens_hsa000520.26631064
131Starch and sucrose metabolism_Homo sapiens_hsa005000.25345518
132mRNA surveillance pathway_Homo sapiens_hsa030150.24974847
133Pentose phosphate pathway_Homo sapiens_hsa000300.24733166
134Vibrio cholerae infection_Homo sapiens_hsa051100.24356775
135Transcriptional misregulation in cancer_Homo sapiens_hsa052020.21849102
136Longevity regulating pathway - mammal_Homo sapiens_hsa042110.21771985
137Huntingtons disease_Homo sapiens_hsa050160.19158512
138Propanoate metabolism_Homo sapiens_hsa006400.17984896
139Endocytosis_Homo sapiens_hsa041440.16444339
140Fatty acid metabolism_Homo sapiens_hsa012120.15318144

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