

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of gamma-delta T cell activation (GO:0046645) | 6.57759534 |
| 2 | regulation of B cell receptor signaling pathway (GO:0050855) | 5.90261760 |
| 3 | negative regulation of cell killing (GO:0031342) | 5.68385211 |
| 4 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.68385211 |
| 5 | B cell receptor signaling pathway (GO:0050853) | 5.47547584 |
| 6 | negative thymic T cell selection (GO:0045060) | 5.27925695 |
| 7 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 5.24311304 |
| 8 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.21950604 |
| 9 | negative T cell selection (GO:0043383) | 5.15509279 |
| 10 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.10660742 |
| 11 | positive thymic T cell selection (GO:0045059) | 5.07980009 |
| 12 | regulation of gamma-delta T cell activation (GO:0046643) | 4.91111388 |
| 13 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.80281421 |
| 14 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.80153037 |
| 15 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.77103261 |
| 16 | thymic T cell selection (GO:0045061) | 4.66364280 |
| 17 | positive T cell selection (GO:0043368) | 4.65841669 |
| 18 | T cell selection (GO:0045058) | 4.45587217 |
| 19 | positive regulation of B cell differentiation (GO:0045579) | 4.28711594 |
| 20 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 4.24323253 |
| 21 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 4.24323253 |
| 22 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 4.24323253 |
| 23 | modulation by symbiont of host immune response (GO:0052553) | 4.24323253 |
| 24 | positive regulation by symbiont of host defense response (GO:0052509) | 4.24323253 |
| 25 | modulation by symbiont of host defense response (GO:0052031) | 4.24323253 |
| 26 | T cell migration (GO:0072678) | 4.23528779 |
| 27 | regulation of B cell differentiation (GO:0045577) | 4.19678159 |
| 28 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 4.14235999 |
| 29 | response to interleukin-15 (GO:0070672) | 4.06258813 |
| 30 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 3.97557019 |
| 31 | positive regulation of granulocyte differentiation (GO:0030854) | 3.89240644 |
| 32 | leukocyte aggregation (GO:0070486) | 3.86392134 |
| 33 | detection of other organism (GO:0098543) | 3.78225109 |
| 34 | detection of bacterium (GO:0016045) | 3.76628766 |
| 35 | B cell homeostasis (GO:0001782) | 3.75528812 |
| 36 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 3.75398340 |
| 37 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.68149436 |
| 38 | germinal center formation (GO:0002467) | 3.67997550 |
| 39 | tolerance induction (GO:0002507) | 3.67182701 |
| 40 | histone H3-K36 demethylation (GO:0070544) | 3.59514745 |
| 41 | macrophage activation involved in immune response (GO:0002281) | 3.54721782 |
| 42 | cellular response to interleukin-15 (GO:0071350) | 3.51604050 |
| 43 | negative regulation of T cell mediated immunity (GO:0002710) | 3.50946342 |
| 44 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.48490783 |
| 45 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.47796250 |
| 46 | response to muramyl dipeptide (GO:0032495) | 3.45452385 |
| 47 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.44333525 |
| 48 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.40770323 |
| 49 | cellular extravasation (GO:0045123) | 3.28093786 |
| 50 | T cell homeostasis (GO:0043029) | 3.27150143 |
| 51 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.23700760 |
| 52 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.18002165 |
| 53 | lymphocyte homeostasis (GO:0002260) | 3.14797568 |
| 54 | response to type I interferon (GO:0034340) | 3.13757924 |
| 55 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.13262676 |
| 56 | regulation of T cell tolerance induction (GO:0002664) | 3.11826280 |
| 57 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.09504165 |
| 58 | cellular response to type I interferon (GO:0071357) | 3.09433350 |
| 59 | type I interferon signaling pathway (GO:0060337) | 3.09433350 |
| 60 | positive regulation of Rap GTPase activity (GO:0032854) | 3.08159817 |
| 61 | B cell proliferation (GO:0042100) | 3.04748836 |
| 62 | immunoglobulin mediated immune response (GO:0016064) | 3.04590013 |
| 63 | detection of external biotic stimulus (GO:0098581) | 3.03848134 |
| 64 | regulation of granulocyte differentiation (GO:0030852) | 3.03283320 |
| 65 | NIK/NF-kappaB signaling (GO:0038061) | 3.01226101 |
| 66 | natural killer cell differentiation (GO:0001779) | 2.98644778 |
| 67 | regulation of histone H3-K27 methylation (GO:0061085) | 2.98451180 |
| 68 | regulation of necroptotic process (GO:0060544) | 2.96481503 |
| 69 | negative regulation of interleukin-12 production (GO:0032695) | 2.94346447 |
| 70 | defense response to protozoan (GO:0042832) | 2.93666491 |
| 71 | interferon-gamma production (GO:0032609) | 2.92955692 |
| 72 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 2.90926693 |
| 73 | T cell receptor signaling pathway (GO:0050852) | 2.90346521 |
| 74 | activated T cell proliferation (GO:0050798) | 2.89497613 |
| 75 | myeloid cell activation involved in immune response (GO:0002275) | 2.88448473 |
| 76 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.88241523 |
| 77 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 2.86238848 |
| 78 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.85846931 |
| 79 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.82832795 |
| 80 | negative regulation of innate immune response (GO:0045824) | 2.82333227 |
| 81 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.81779307 |
| 82 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.81779307 |
| 83 | mucosal-associated lymphoid tissue development (GO:0048537) | 2.81752648 |
| 84 | Peyers patch development (GO:0048541) | 2.81752648 |
| 85 | regulation of tolerance induction (GO:0002643) | 2.79495404 |
| 86 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.79233557 |
| 87 | positive regulation of interleukin-2 production (GO:0032743) | 2.78938186 |
| 88 | positive regulation of B cell activation (GO:0050871) | 2.78106426 |
| 89 | mast cell activation (GO:0045576) | 2.76011901 |
| 90 | myeloid dendritic cell activation (GO:0001773) | 2.75848505 |
| 91 | positive regulation of isotype switching (GO:0045830) | 2.75413606 |
| 92 | regulation of MHC class I biosynthetic process (GO:0045343) | 2.74639647 |
| 93 | neutrophil activation involved in immune response (GO:0002283) | 2.74059850 |
| 94 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 2.72847212 |
| 95 | response to protozoan (GO:0001562) | 2.72689638 |
| 96 | regulation of antigen processing and presentation (GO:0002577) | 2.70330930 |
| 97 | response to host immune response (GO:0052572) | 2.70155383 |
| 98 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 2.70155383 |
| 99 | negative regulation of phagocytosis (GO:0050765) | 2.69932767 |
| 100 | leukocyte homeostasis (GO:0001776) | 2.69919885 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.26868374 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.77465487 |
| 3 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.35152942 |
| 4 | MYC_22102868_ChIP-Seq_BL_Human | 4.10818527 |
| 5 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.30221531 |
| 6 | VDR_21846776_ChIP-Seq_THP-1_Human | 3.17902854 |
| 7 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.13030367 |
| 8 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.98518398 |
| 9 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.87316781 |
| 10 | MAF_26560356_Chip-Seq_TH1_Human | 2.85274288 |
| 11 | MYB_26560356_Chip-Seq_TH2_Human | 2.81752945 |
| 12 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.73830659 |
| 13 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.71384267 |
| 14 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.61169539 |
| 15 | MYB_26560356_Chip-Seq_TH1_Human | 2.59769051 |
| 16 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.58544956 |
| 17 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.56199958 |
| 18 | UTX_26944678_Chip-Seq_JUKART_Human | 2.53932110 |
| 19 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.44207294 |
| 20 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.42772332 |
| 21 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.39959979 |
| 22 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.36955298 |
| 23 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.35890024 |
| 24 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.33504575 |
| 25 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.32664532 |
| 26 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.32523648 |
| 27 | MAF_26560356_Chip-Seq_TH2_Human | 2.31215309 |
| 28 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.29945263 |
| 29 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.22878212 |
| 30 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.21183755 |
| 31 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 2.15057445 |
| 32 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.14786417 |
| 33 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.14735836 |
| 34 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 2.13959485 |
| 35 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 2.12266465 |
| 36 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.11828069 |
| 37 | SPI1_23127762_ChIP-Seq_K562_Human | 2.06931068 |
| 38 | KDM2B_26808549_Chip-Seq_DND41_Human | 2.01706217 |
| 39 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.99927054 |
| 40 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.92636062 |
| 41 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.90984860 |
| 42 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.87740052 |
| 43 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.80021299 |
| 44 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.75101457 |
| 45 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.69150417 |
| 46 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.63907720 |
| 47 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.62228318 |
| 48 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.62220806 |
| 49 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.49107360 |
| 50 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.48114406 |
| 51 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.47252560 |
| 52 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.42504510 |
| 53 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.39991241 |
| 54 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.36581177 |
| 55 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.35458950 |
| 56 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.34995221 |
| 57 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.33811489 |
| 58 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.33800355 |
| 59 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.32585606 |
| 60 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.30101606 |
| 61 | GATA3_26560356_Chip-Seq_TH2_Human | 1.29746712 |
| 62 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.29659563 |
| 63 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.27888676 |
| 64 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.25928226 |
| 65 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.21974939 |
| 66 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.21765495 |
| 67 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.20839585 |
| 68 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.18191427 |
| 69 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.16777772 |
| 70 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.15962576 |
| 71 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.14966804 |
| 72 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.13491326 |
| 73 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.11212991 |
| 74 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.09439633 |
| 75 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.09434880 |
| 76 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.07705406 |
| 77 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.07264535 |
| 78 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.07120548 |
| 79 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.05189999 |
| 80 | GATA1_19941826_ChIP-Seq_K562_Human | 1.04371612 |
| 81 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.03607247 |
| 82 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.03578975 |
| 83 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.02756035 |
| 84 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.00215664 |
| 85 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.00029536 |
| 86 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.98813267 |
| 87 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.98079698 |
| 88 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.97813263 |
| 89 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.97358009 |
| 90 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.96329744 |
| 91 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.94834843 |
| 92 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.92391209 |
| 93 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.91706282 |
| 94 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.89092670 |
| 95 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.86316176 |
| 96 | P68_20966046_ChIP-Seq_HELA_Human | 0.84746492 |
| 97 | CTCF_21964334_ChIP-Seq_BJAB-B_Human | 0.83189725 |
| 98 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.79831250 |
| 99 | SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human | 0.79220615 |
| 100 | P300_27268052_Chip-Seq_Bcells_Human | 0.78244397 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003763_abnormal_thymus_physiology | 4.21380846 |
| 2 | MP0001835_abnormal_antigen_presentation | 3.66370373 |
| 3 | MP0001800_abnormal_humoral_immune | 3.48577529 |
| 4 | MP0003436_decreased_susceptibility_to | 3.30482151 |
| 5 | MP0000685_abnormal_immune_system | 3.27485761 |
| 6 | MP0003303_peritoneal_inflammation | 3.14348197 |
| 7 | MP0005387_immune_system_phenotype | 3.11683878 |
| 8 | MP0001790_abnormal_immune_system | 3.11683878 |
| 9 | MP0005000_abnormal_immune_tolerance | 2.84537000 |
| 10 | MP0005671_abnormal_response_to | 2.83513808 |
| 11 | MP0003300_gastrointestinal_ulcer | 2.77075073 |
| 12 | MP0003724_increased_susceptibility_to | 2.76188808 |
| 13 | MP0002452_abnormal_antigen_presenting | 2.71196196 |
| 14 | MP0002420_abnormal_adaptive_immunity | 2.69905112 |
| 15 | MP0002723_abnormal_immune_serum | 2.68819378 |
| 16 | MP0001819_abnormal_immune_cell | 2.65095368 |
| 17 | MP0002398_abnormal_bone_marrow | 2.50353787 |
| 18 | MP0002396_abnormal_hematopoietic_system | 2.49824520 |
| 19 | MP0002419_abnormal_innate_immunity | 2.34542715 |
| 20 | MP0005025_abnormal_response_to | 2.34492739 |
| 21 | MP0000716_abnormal_immune_system | 2.25338347 |
| 22 | MP0009333_abnormal_splenocyte_physiolog | 2.17701704 |
| 23 | MP0000703_abnormal_thymus_morphology | 2.14545396 |
| 24 | MP0000689_abnormal_spleen_morphology | 2.10144675 |
| 25 | MP0002405_respiratory_system_inflammati | 2.07650487 |
| 26 | MP0004381_abnormal_hair_follicle | 2.00990256 |
| 27 | MP0002722_abnormal_immune_system | 2.00779397 |
| 28 | MP0010155_abnormal_intestine_physiology | 1.92815721 |
| 29 | MP0002138_abnormal_hepatobiliary_system | 1.88398635 |
| 30 | MP0001873_stomach_inflammation | 1.88254133 |
| 31 | MP0008260_abnormal_autophagy | 1.86837115 |
| 32 | MP0009785_altered_susceptibility_to | 1.85346952 |
| 33 | MP0002429_abnormal_blood_cell | 1.84814109 |
| 34 | MP0005310_abnormal_salivary_gland | 1.78014301 |
| 35 | MP0002166_altered_tumor_susceptibility | 1.73247107 |
| 36 | MP0005464_abnormal_platelet_physiology | 1.73119876 |
| 37 | MP0004947_skin_inflammation | 1.67829421 |
| 38 | MP0003866_abnormal_defecation | 1.66965697 |
| 39 | MP0000465_gastrointestinal_hemorrhage | 1.61008938 |
| 40 | MP0008057_abnormal_DNA_replication | 1.60226573 |
| 41 | MP0003828_pulmonary_edema | 1.57005466 |
| 42 | MP0002148_abnormal_hypersensitivity_rea | 1.56248195 |
| 43 | MP0001845_abnormal_inflammatory_respons | 1.53624701 |
| 44 | MP0002009_preneoplasia | 1.53399607 |
| 45 | MP0004808_abnormal_hematopoietic_stem | 1.47412672 |
| 46 | MP0001986_abnormal_taste_sensitivity | 1.44125401 |
| 47 | MP0003172_abnormal_lysosome_physiology | 1.36735990 |
| 48 | MP0002933_joint_inflammation | 1.34794070 |
| 49 | MP0003091_abnormal_cell_migration | 1.29391964 |
| 50 | MP0009278_abnormal_bone_marrow | 1.28993261 |
| 51 | MP0003191_abnormal_cellular_cholesterol | 1.28097434 |
| 52 | MP0002132_abnormal_respiratory_system | 1.27331563 |
| 53 | MP0001533_abnormal_skeleton_physiology | 1.26348118 |
| 54 | MP0005075_abnormal_melanosome_morpholog | 1.11697972 |
| 55 | MP0000858_altered_metastatic_potential | 1.11158537 |
| 56 | MP0005451_abnormal_body_composition | 1.09508912 |
| 57 | MP0006082_CNS_inflammation | 1.08486098 |
| 58 | MP0002006_tumorigenesis | 1.07310539 |
| 59 | MP0008469_abnormal_protein_level | 1.06516543 |
| 60 | MP0001851_eye_inflammation | 1.04652644 |
| 61 | MP0002019_abnormal_tumor_incidence | 0.99032592 |
| 62 | MP0002998_abnormal_bone_remodeling | 0.98040807 |
| 63 | MP0001853_heart_inflammation | 0.96774366 |
| 64 | MP0000490_abnormal_crypts_of | 0.93464842 |
| 65 | MP0005397_hematopoietic_system_phenotyp | 0.91624176 |
| 66 | MP0001545_abnormal_hematopoietic_system | 0.91624176 |
| 67 | MP0005076_abnormal_cell_differentiation | 0.91062843 |
| 68 | MP0000015_abnormal_ear_pigmentation | 0.90937576 |
| 69 | MP0003045_fibrosis | 0.90352135 |
| 70 | MP0000249_abnormal_blood_vessel | 0.89156802 |
| 71 | MP0003183_abnormal_peptide_metabolism | 0.86826806 |
| 72 | MP0004883_abnormal_blood_vessel | 0.86000145 |
| 73 | MP0002928_abnormal_bile_duct | 0.79546338 |
| 74 | MP0001348_abnormal_lacrimal_gland | 0.77841849 |
| 75 | MP0003279_aneurysm | 0.77689200 |
| 76 | MP0001663_abnormal_digestive_system | 0.74270938 |
| 77 | MP0005621_abnormal_cell_physiology | 0.72551238 |
| 78 | MP0008961_abnormal_basal_metabolism | 0.71959240 |
| 79 | MP0009764_decreased_sensitivity_to | 0.71560965 |
| 80 | MP0004510_myositis | 0.70381840 |
| 81 | MP0000767_abnormal_smooth_muscle | 0.67909074 |
| 82 | MP0009115_abnormal_fat_cell | 0.66843208 |
| 83 | MP0005058_abnormal_lysosome_morphology | 0.64246953 |
| 84 | MP0005167_abnormal_blood-brain_barrier | 0.58316460 |
| 85 | MP0003448_altered_tumor_morphology | 0.57632096 |
| 86 | MP0004130_abnormal_muscle_cell | 0.57182523 |
| 87 | MP0005409_darkened_coat_color | 0.55186252 |
| 88 | MP0000313_abnormal_cell_death | 0.55019455 |
| 89 | MP0002332_abnormal_exercise_endurance | 0.54550685 |
| 90 | MP0009763_increased_sensitivity_to | 0.54225771 |
| 91 | MP0002136_abnormal_kidney_physiology | 0.53356926 |
| 92 | MP0001879_abnormal_lymphatic_vessel | 0.52444556 |
| 93 | MP0008874_decreased_physiological_sensi | 0.52267511 |
| 94 | MP0001915_intracranial_hemorrhage | 0.51024072 |
| 95 | MP0003221_abnormal_cardiomyocyte_apopto | 0.50433969 |
| 96 | MP0000371_diluted_coat_color | 0.50380126 |
| 97 | MP0005166_decreased_susceptibility_to | 0.49965616 |
| 98 | MP0005164_abnormal_response_to | 0.49178236 |
| 99 | MP0003077_abnormal_cell_cycle | 0.47611044 |
| 100 | MP0000609_abnormal_liver_physiology | 0.47554937 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Eczematoid dermatitis (HP:0000976) | 5.32476740 |
| 2 | Panhypogammaglobulinemia (HP:0003139) | 5.15150479 |
| 3 | Agammaglobulinemia (HP:0004432) | 5.02245493 |
| 4 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 4.88595919 |
| 5 | Recurrent bacterial skin infections (HP:0005406) | 4.48177218 |
| 6 | Colitis (HP:0002583) | 4.36602069 |
| 7 | Meningitis (HP:0001287) | 4.28459593 |
| 8 | Recurrent fungal infections (HP:0002841) | 4.23927789 |
| 9 | Recurrent abscess formation (HP:0002722) | 4.22453183 |
| 10 | Recurrent viral infections (HP:0004429) | 4.21678039 |
| 11 | Spontaneous hematomas (HP:0007420) | 3.96283349 |
| 12 | Cellulitis (HP:0100658) | 3.94968897 |
| 13 | T lymphocytopenia (HP:0005403) | 3.86845212 |
| 14 | Recurrent cutaneous fungal infections (HP:0011370) | 3.84656888 |
| 15 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.84656888 |
| 16 | Mediastinal lymphadenopathy (HP:0100721) | 3.84058703 |
| 17 | Pustule (HP:0200039) | 3.69963529 |
| 18 | Inflammation of the large intestine (HP:0002037) | 3.69666034 |
| 19 | Gastrointestinal inflammation (HP:0004386) | 3.66029048 |
| 20 | Abnormality of T cell number (HP:0011839) | 3.63918310 |
| 21 | Gastrointestinal stroma tumor (HP:0100723) | 3.61512993 |
| 22 | Myositis (HP:0100614) | 3.55381269 |
| 23 | Lymphopenia (HP:0001888) | 3.50141076 |
| 24 | Vasculitis (HP:0002633) | 3.40629159 |
| 25 | Recurrent skin infections (HP:0001581) | 3.39122489 |
| 26 | Abnormality of macrophages (HP:0004311) | 3.36599550 |
| 27 | Abnormality of T cells (HP:0002843) | 3.35668277 |
| 28 | IgM deficiency (HP:0002850) | 3.33790305 |
| 29 | Verrucae (HP:0200043) | 3.32900355 |
| 30 | Papilloma (HP:0012740) | 3.32900355 |
| 31 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 3.27417974 |
| 32 | Recurrent bronchitis (HP:0002837) | 3.19690133 |
| 33 | Abnormality of the fingertips (HP:0001211) | 3.17121265 |
| 34 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.15959227 |
| 35 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.13970443 |
| 36 | Gastrointestinal infarctions (HP:0005244) | 3.13718073 |
| 37 | Viral hepatitis (HP:0006562) | 3.10987018 |
| 38 | Encephalitis (HP:0002383) | 3.09042726 |
| 39 | Prolonged bleeding time (HP:0003010) | 3.01508323 |
| 40 | Recurrent sinusitis (HP:0011108) | 2.94112195 |
| 41 | Retrobulbar optic neuritis (HP:0100654) | 2.93552520 |
| 42 | Optic neuritis (HP:0100653) | 2.93552520 |
| 43 | Abnormality of T cell physiology (HP:0011840) | 2.93274128 |
| 44 | Chest pain (HP:0100749) | 2.91447327 |
| 45 | Orchitis (HP:0100796) | 2.90557532 |
| 46 | Increased IgE level (HP:0003212) | 2.89031888 |
| 47 | Stomatitis (HP:0010280) | 2.88863289 |
| 48 | Obstructive lung disease (HP:0006536) | 2.85334265 |
| 49 | Chronic obstructive pulmonary disease (HP:0006510) | 2.85334265 |
| 50 | Granulocytopenia (HP:0001913) | 2.82252142 |
| 51 | Basal cell carcinoma (HP:0002671) | 2.77975337 |
| 52 | Osteomyelitis (HP:0002754) | 2.74619174 |
| 53 | Epistaxis (HP:0000421) | 2.73970492 |
| 54 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.71797830 |
| 55 | Hypochromic anemia (HP:0001931) | 2.71445248 |
| 56 | IgA deficiency (HP:0002720) | 2.70085786 |
| 57 | Emphysema (HP:0002097) | 2.63995740 |
| 58 | Gingivitis (HP:0000230) | 2.60565878 |
| 59 | Hypoplasia of the thymus (HP:0000778) | 2.53808981 |
| 60 | Pulmonary infiltrates (HP:0002113) | 2.47396455 |
| 61 | IgG deficiency (HP:0004315) | 2.47070967 |
| 62 | Fatigue (HP:0012378) | 2.46217545 |
| 63 | Autoimmune hemolytic anemia (HP:0001890) | 2.43385733 |
| 64 | Restrictive lung disease (HP:0002091) | 2.42747161 |
| 65 | Chronic diarrhea (HP:0002028) | 2.41854062 |
| 66 | Papilledema (HP:0001085) | 2.41801063 |
| 67 | Slow saccadic eye movements (HP:0000514) | 2.40686474 |
| 68 | Hypochromic microcytic anemia (HP:0004840) | 2.36541483 |
| 69 | Lymphoma (HP:0002665) | 2.34702633 |
| 70 | Hemoptysis (HP:0002105) | 2.33645021 |
| 71 | Leukocytosis (HP:0001974) | 2.31998501 |
| 72 | Hematochezia (HP:0002573) | 2.29369286 |
| 73 | Arterial thrombosis (HP:0004420) | 2.27787506 |
| 74 | Sepsis (HP:0100806) | 2.25100728 |
| 75 | Recurrent lower respiratory tract infections (HP:0002783) | 2.24774610 |
| 76 | Eosinophilia (HP:0001880) | 2.24388925 |
| 77 | Severe combined immunodeficiency (HP:0004430) | 2.23586545 |
| 78 | Recurrent pneumonia (HP:0006532) | 2.19527611 |
| 79 | Microcytic anemia (HP:0001935) | 2.15457253 |
| 80 | Gingival bleeding (HP:0000225) | 2.14891360 |
| 81 | Urticaria (HP:0001025) | 2.13265674 |
| 82 | Abnormality of B cell number (HP:0010975) | 2.11145451 |
| 83 | Teleangiectasia of the skin (HP:0100585) | 2.05595587 |
| 84 | Pulmonary embolism (HP:0002204) | 2.03865447 |
| 85 | Abnormality of eosinophils (HP:0001879) | 2.03848578 |
| 86 | Abnormality of the peritoneum (HP:0002585) | 2.03599699 |
| 87 | Keratoconjunctivitis sicca (HP:0001097) | 2.03412321 |
| 88 | Skin ulcer (HP:0200042) | 1.93866654 |
| 89 | Chronic otitis media (HP:0000389) | 1.93761902 |
| 90 | Hepatitis (HP:0012115) | 1.93066208 |
| 91 | Thrombocytosis (HP:0001894) | 1.90662848 |
| 92 | Autoimmune thrombocytopenia (HP:0001973) | 1.89581772 |
| 93 | Keratoconjunctivitis (HP:0001096) | 1.89219174 |
| 94 | Increased IgM level (HP:0003496) | 1.88886547 |
| 95 | Acute hepatic failure (HP:0006554) | 1.87833839 |
| 96 | Abnormality of the pleura (HP:0002103) | 1.84153521 |
| 97 | B lymphocytopenia (HP:0010976) | 1.80170330 |
| 98 | Subacute progressive viral hepatitis (HP:0006572) | 1.79750288 |
| 99 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 1.79709522 |
| 100 | Combined immunodeficiency (HP:0005387) | 1.78452729 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K1 | 4.98970995 |
| 2 | RIPK4 | 3.60843277 |
| 3 | PRPF4B | 3.34734700 |
| 4 | BLK | 3.12021328 |
| 5 | MAP3K10 | 2.92559033 |
| 6 | MAP3K13 | 2.90522227 |
| 7 | FES | 2.31404696 |
| 8 | ERN1 | 2.28890669 |
| 9 | BTK | 2.27441910 |
| 10 | MAP3K14 | 2.25412943 |
| 11 | CDK12 | 2.24456189 |
| 12 | TYK2 | 2.16710818 |
| 13 | SYK | 1.94640386 |
| 14 | IRAK4 | 1.91976044 |
| 15 | ZAP70 | 1.77551073 |
| 16 | JAK3 | 1.77350445 |
| 17 | ITK | 1.76285756 |
| 18 | CSK | 1.75043357 |
| 19 | MAP2K3 | 1.73293354 |
| 20 | GRK6 | 1.67105913 |
| 21 | TEC | 1.64103239 |
| 22 | TXK | 1.63623582 |
| 23 | TRIB3 | 1.61631057 |
| 24 | SIK2 | 1.60958734 |
| 25 | IKBKE | 1.60447499 |
| 26 | HCK | 1.56722356 |
| 27 | TNK2 | 1.48470552 |
| 28 | JAK1 | 1.35962446 |
| 29 | CDK4 | 1.32558219 |
| 30 | MAP3K7 | 1.28525740 |
| 31 | LYN | 1.27218800 |
| 32 | SMG1 | 1.25168308 |
| 33 | TAOK3 | 1.22313975 |
| 34 | LCK | 1.20094085 |
| 35 | SIK3 | 1.19378156 |
| 36 | FGFR4 | 1.18410121 |
| 37 | PASK | 1.16103274 |
| 38 | CSF1R | 1.15727867 |
| 39 | CDC42BPA | 1.15459757 |
| 40 | NLK | 1.13450124 |
| 41 | MARK2 | 1.12666252 |
| 42 | TBK1 | 1.10612246 |
| 43 | TIE1 | 1.09923311 |
| 44 | MARK3 | 1.06594790 |
| 45 | IKBKB | 1.05498196 |
| 46 | FGFR3 | 1.02790852 |
| 47 | BRD4 | 0.99669077 |
| 48 | MAPK11 | 0.95586082 |
| 49 | STK10 | 0.94720705 |
| 50 | MAPK12 | 0.94250937 |
| 51 | MELK | 0.93363961 |
| 52 | PDK1 | 0.88192041 |
| 53 | JAK2 | 0.87741628 |
| 54 | PRKCQ | 0.85893124 |
| 55 | MAPK7 | 0.85855442 |
| 56 | FGR | 0.84962969 |
| 57 | TGFBR2 | 0.79674499 |
| 58 | EPHB1 | 0.78462978 |
| 59 | BMPR2 | 0.77677832 |
| 60 | EEF2K | 0.75715738 |
| 61 | PIM1 | 0.74625554 |
| 62 | KIT | 0.73547591 |
| 63 | CAMKK1 | 0.71366700 |
| 64 | MAP3K1 | 0.69172717 |
| 65 | HIPK2 | 0.69117674 |
| 66 | SIK1 | 0.68347904 |
| 67 | ICK | 0.64326506 |
| 68 | CAMKK2 | 0.62633021 |
| 69 | PTK2B | 0.62573823 |
| 70 | PDPK1 | 0.62298010 |
| 71 | KDR | 0.61601022 |
| 72 | CHUK | 0.59966623 |
| 73 | YES1 | 0.56209050 |
| 74 | MAP3K3 | 0.54170970 |
| 75 | WNK1 | 0.53859826 |
| 76 | CDK6 | 0.51751056 |
| 77 | PRKD2 | 0.51181990 |
| 78 | KSR2 | 0.51013943 |
| 79 | CDK9 | 0.50846417 |
| 80 | TESK2 | 0.50271538 |
| 81 | SGK3 | 0.48832079 |
| 82 | TRPM7 | 0.48347330 |
| 83 | STK4 | 0.46678959 |
| 84 | SGK2 | 0.45018526 |
| 85 | TAOK1 | 0.43852548 |
| 86 | PIK3CG | 0.41670820 |
| 87 | RPS6KL1 | 0.40693563 |
| 88 | RPS6KC1 | 0.40693563 |
| 89 | LRRK2 | 0.40300188 |
| 90 | MAP3K11 | 0.40064670 |
| 91 | NEK9 | 0.38977569 |
| 92 | PTK6 | 0.38570040 |
| 93 | FYN | 0.37928913 |
| 94 | PKN2 | 0.37575823 |
| 95 | PRKCH | 0.37175194 |
| 96 | CAMK4 | 0.36333639 |
| 97 | RPS6KA6 | 0.34499704 |
| 98 | TGFBR1 | 0.30135484 |
| 99 | TYRO3 | 0.29609707 |
| 100 | MAP3K8 | 0.29444324 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.52691020 |
| 2 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 3.13720725 |
| 3 | Allograft rejection_Homo sapiens_hsa05330 | 2.59593077 |
| 4 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.47422623 |
| 5 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.47364414 |
| 6 | Leishmaniasis_Homo sapiens_hsa05140 | 2.34254766 |
| 7 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.29451558 |
| 8 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.19206441 |
| 9 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 2.18537505 |
| 10 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.16455230 |
| 11 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.95617576 |
| 12 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.92288430 |
| 13 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.89152554 |
| 14 | Measles_Homo sapiens_hsa05162 | 1.78559523 |
| 15 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.77681655 |
| 16 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.75829792 |
| 17 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.75286925 |
| 18 | Viral myocarditis_Homo sapiens_hsa05416 | 1.64311400 |
| 19 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.63894692 |
| 20 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.61550906 |
| 21 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.61156923 |
| 22 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.60361175 |
| 23 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.59241390 |
| 24 | Asthma_Homo sapiens_hsa05310 | 1.58730325 |
| 25 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.56452867 |
| 26 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.55145946 |
| 27 | Influenza A_Homo sapiens_hsa05164 | 1.54286067 |
| 28 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.49249927 |
| 29 | Hepatitis B_Homo sapiens_hsa05161 | 1.47601121 |
| 30 | Tuberculosis_Homo sapiens_hsa05152 | 1.47253201 |
| 31 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.41830123 |
| 32 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.33688273 |
| 33 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.32537733 |
| 34 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.25609599 |
| 35 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.23292077 |
| 36 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.22452593 |
| 37 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.15952329 |
| 38 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.12961376 |
| 39 | Apoptosis_Homo sapiens_hsa04210 | 1.12537560 |
| 40 | Other glycan degradation_Homo sapiens_hsa00511 | 1.11073518 |
| 41 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.10153456 |
| 42 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.09562995 |
| 43 | Platelet activation_Homo sapiens_hsa04611 | 1.08623020 |
| 44 | HTLV-I infection_Homo sapiens_hsa05166 | 1.03853543 |
| 45 | Hepatitis C_Homo sapiens_hsa05160 | 0.99965091 |
| 46 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.98298772 |
| 47 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.97774630 |
| 48 | Malaria_Homo sapiens_hsa05144 | 0.96678774 |
| 49 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.96255609 |
| 50 | Colorectal cancer_Homo sapiens_hsa05210 | 0.95647190 |
| 51 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.95631182 |
| 52 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.95307992 |
| 53 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.92554711 |
| 54 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.92472074 |
| 55 | Endometrial cancer_Homo sapiens_hsa05213 | 0.91027674 |
| 56 | Prostate cancer_Homo sapiens_hsa05215 | 0.86193977 |
| 57 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.86187044 |
| 58 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.84903477 |
| 59 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.82255313 |
| 60 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.79767677 |
| 61 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.79659453 |
| 62 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.79461754 |
| 63 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.78771322 |
| 64 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.77402602 |
| 65 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.71387193 |
| 66 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.69710388 |
| 67 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.68636476 |
| 68 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.66009798 |
| 69 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.64983810 |
| 70 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.64462219 |
| 71 | Insulin resistance_Homo sapiens_hsa04931 | 0.63020359 |
| 72 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.62453902 |
| 73 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.62416072 |
| 74 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.61178002 |
| 75 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.60678708 |
| 76 | Glioma_Homo sapiens_hsa05214 | 0.59285373 |
| 77 | Endocytosis_Homo sapiens_hsa04144 | 0.54308680 |
| 78 | Shigellosis_Homo sapiens_hsa05131 | 0.54210243 |
| 79 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.52216763 |
| 80 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.52207281 |
| 81 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.51774499 |
| 82 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.51030571 |
| 83 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.50812776 |
| 84 | Thyroid cancer_Homo sapiens_hsa05216 | 0.50607689 |
| 85 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.49635807 |
| 86 | Legionellosis_Homo sapiens_hsa05134 | 0.49427625 |
| 87 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.49330767 |
| 88 | Pertussis_Homo sapiens_hsa05133 | 0.47258426 |
| 89 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.46903232 |
| 90 | Phagosome_Homo sapiens_hsa04145 | 0.46724877 |
| 91 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.44484999 |
| 92 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.41919810 |
| 93 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.39500633 |
| 94 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.38772004 |
| 95 | Long-term potentiation_Homo sapiens_hsa04720 | 0.37739931 |
| 96 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.36184360 |
| 97 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.33936159 |
| 98 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.33361358 |
| 99 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.33234856 |
| 100 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.33128564 |

