GRPEL1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.10267672
2ribosome assembly (GO:0042255)5.07838425
3ATP synthesis coupled proton transport (GO:0015986)4.65525183
4energy coupled proton transport, down electrochemical gradient (GO:0015985)4.65525183
5chaperone-mediated protein transport (GO:0072321)4.59271271
6proteasome assembly (GO:0043248)4.40597204
7establishment of integrated proviral latency (GO:0075713)4.33198694
8mitotic metaphase plate congression (GO:0007080)4.08896677
9L-phenylalanine metabolic process (GO:0006558)4.03465131
10erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)4.03465131
11respiratory electron transport chain (GO:0022904)4.00902443
12mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.98161101
13pseudouridine synthesis (GO:0001522)3.94087446
14electron transport chain (GO:0022900)3.90306531
15ribosome biogenesis (GO:0042254)3.84510580
16DNA deamination (GO:0045006)3.84282296
17glycine metabolic process (GO:0006544)3.83706203
18aldehyde catabolic process (GO:0046185)3.82334643
19L-phenylalanine catabolic process (GO:0006559)3.82149288
20erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.82149288
21cullin deneddylation (GO:0010388)3.78820777
22* protein targeting to mitochondrion (GO:0006626)3.74028324
23oxidative phosphorylation (GO:0006119)3.73595828
24serine family amino acid biosynthetic process (GO:0009070)3.71075705
25regulation of ubiquitin-protein transferase activity (GO:0051438)3.69420482
26establishment of viral latency (GO:0019043)3.66902355
27rRNA processing (GO:0006364)3.64732881
28regulation of cellular amino acid metabolic process (GO:0006521)3.60639353
29DNA strand elongation involved in DNA replication (GO:0006271)3.60191356
30telomere maintenance via semi-conservative replication (GO:0032201)3.59659014
31protein deneddylation (GO:0000338)3.58769513
32regulation of ligase activity (GO:0051340)3.58438355
33maturation of 5.8S rRNA (GO:0000460)3.58033268
34glyoxylate metabolic process (GO:0046487)3.56762450
35purine nucleobase biosynthetic process (GO:0009113)3.56568881
36spliceosomal snRNP assembly (GO:0000387)3.54895026
37DNA strand elongation (GO:0022616)3.51966595
38negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.51960448
39L-methionine salvage (GO:0071267)3.47080545
40L-methionine biosynthetic process (GO:0071265)3.47080545
41amino acid salvage (GO:0043102)3.47080545
42rRNA metabolic process (GO:0016072)3.46655928
43* protein localization to mitochondrion (GO:0070585)3.44221914
44aromatic amino acid family catabolic process (GO:0009074)3.44166691
45cysteine metabolic process (GO:0006534)3.42738512
46serine family amino acid metabolic process (GO:0009069)3.42190448
47nucleobase biosynthetic process (GO:0046112)3.41828863
48serine family amino acid catabolic process (GO:0009071)3.39680897
49* establishment of protein localization to mitochondrion (GO:0072655)3.37508554
50metaphase plate congression (GO:0051310)3.36207493
51positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.33932901
52transcription from mitochondrial promoter (GO:0006390)3.33517541
53L-serine metabolic process (GO:0006563)3.31566921
54regulation of translational termination (GO:0006449)3.31400493
55rRNA methylation (GO:0031167)3.29169526
56mitochondrial RNA metabolic process (GO:0000959)3.25423875
57IMP biosynthetic process (GO:0006188)3.25004612
587-methylguanosine mRNA capping (GO:0006370)3.24817325
59DNA replication checkpoint (GO:0000076)3.24246920
60negative regulation of protein ubiquitination (GO:0031397)3.23925163
61L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.23497835
62CENP-A containing nucleosome assembly (GO:0034080)3.22925316
63regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.22445515
64G1/S transition of mitotic cell cycle (GO:0000082)3.20849139
65cell cycle G1/S phase transition (GO:0044843)3.20849139
66branched-chain amino acid catabolic process (GO:0009083)3.20540580
67lysine metabolic process (GO:0006553)3.20434977
68lysine catabolic process (GO:0006554)3.20434977
69protein maturation by protein folding (GO:0022417)3.20207776
70regulation of mitochondrial translation (GO:0070129)3.20078349
71tricarboxylic acid cycle (GO:0006099)3.17769074
72DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.17240186
73folic acid metabolic process (GO:0046655)3.17030750
74negative regulation of ligase activity (GO:0051352)3.16839784
75negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.16839784
76ribosomal small subunit assembly (GO:0000028)3.16672381
77establishment of protein localization to mitochondrial membrane (GO:0090151)3.16610570
78anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.15946234
79transcription-coupled nucleotide-excision repair (GO:0006283)3.15709402
807-methylguanosine RNA capping (GO:0009452)3.14564547
81RNA capping (GO:0036260)3.14564547
82formation of translation preinitiation complex (GO:0001731)3.14126775
83mitochondrial respiratory chain complex I assembly (GO:0032981)3.13591245
84NADH dehydrogenase complex assembly (GO:0010257)3.13591245
85mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.13591245
86indole-containing compound catabolic process (GO:0042436)3.11853105
87indolalkylamine catabolic process (GO:0046218)3.11853105
88tryptophan catabolic process (GO:0006569)3.11853105
89signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.10761186
90intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.10761186
91viral mRNA export from host cell nucleus (GO:0046784)3.10103361
92telomere maintenance via recombination (GO:0000722)3.09459667
93NADH metabolic process (GO:0006734)3.09399300
94signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.08916878
95signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.08916878
96signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.08916878
97rRNA modification (GO:0000154)3.08373540
98protein localization to kinetochore (GO:0034501)3.08245515
99ribosomal small subunit biogenesis (GO:0042274)3.08194986
100transcription from RNA polymerase I promoter (GO:0006360)3.07963132
101chromatin remodeling at centromere (GO:0031055)3.07948377
102positive regulation of cell cycle arrest (GO:0071158)3.06097598
103negative regulation of protein modification by small protein conjugation or removal (GO:1903321)3.05343840
104antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.04880775
105triglyceride-rich lipoprotein particle remodeling (GO:0034370)3.03494839
106DNA damage response, signal transduction by p53 class mediator (GO:0030330)3.03440721
107ribosomal large subunit biogenesis (GO:0042273)3.02462061
108signal transduction involved in DNA integrity checkpoint (GO:0072401)3.02330207
109signal transduction involved in DNA damage checkpoint (GO:0072422)3.02330207
110tryptophan metabolic process (GO:0006568)3.01988177
111kynurenine metabolic process (GO:0070189)3.01897853
112DNA damage response, detection of DNA damage (GO:0042769)3.01133734
113termination of RNA polymerase I transcription (GO:0006363)3.00971912
114protein localization to chromosome, centromeric region (GO:0071459)2.99779464
115termination of RNA polymerase III transcription (GO:0006386)2.98954213
116transcription elongation from RNA polymerase III promoter (GO:0006385)2.98954213
117cellular ketone body metabolic process (GO:0046950)2.98004075
118tRNA methylation (GO:0030488)2.97772766
119signal transduction involved in cell cycle checkpoint (GO:0072395)2.97763766
120sulfur amino acid biosynthetic process (GO:0000097)2.97538052
121metallo-sulfur cluster assembly (GO:0031163)2.96794939
122iron-sulfur cluster assembly (GO:0016226)2.96794939
123mitotic sister chromatid segregation (GO:0000070)2.96637431
124histone mRNA metabolic process (GO:0008334)2.96479893
125positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.94619325
126viral transcription (GO:0019083)2.94399458
127DNA catabolic process, exonucleolytic (GO:0000738)2.94267539
128exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.93795355
129translation (GO:0006412)2.91039201
130maturation of SSU-rRNA (GO:0030490)2.89545026
131quinone biosynthetic process (GO:1901663)2.87901833
132ubiquinone biosynthetic process (GO:0006744)2.87901833
133aromatic amino acid family metabolic process (GO:0009072)2.87522364
134sulfur amino acid catabolic process (GO:0000098)2.86416291
135translational termination (GO:0006415)2.85281410
136antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.84543531
137positive regulation of ligase activity (GO:0051351)2.84309840
138protein complex biogenesis (GO:0070271)2.84059432
139ribonucleoprotein complex biogenesis (GO:0022613)2.83830391
140pteridine-containing compound biosynthetic process (GO:0042559)2.80399884
141folic acid-containing compound biosynthetic process (GO:0009396)2.80289364
142mitochondrial respiratory chain complex assembly (GO:0033108)2.79656498
143bile acid biosynthetic process (GO:0006699)2.79317247
144methionine metabolic process (GO:0006555)2.78515788
145amino-acid betaine metabolic process (GO:0006577)2.76640238
146cellular component biogenesis (GO:0044085)2.74680216
147alpha-amino acid catabolic process (GO:1901606)2.73895486
148regulation of cellular amine metabolic process (GO:0033238)2.71976166
149SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.71805361
150branched-chain amino acid metabolic process (GO:0009081)2.71659526
151nucleobase-containing small molecule interconversion (GO:0015949)2.69777588

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.41980063
2ESR1_17901129_ChIP-ChIP_LIVER_Mouse4.12762416
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.99948793
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.70693039
5GABP_17652178_ChIP-ChIP_JURKAT_Human3.69378264
6* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.59780153
7E2F7_22180533_ChIP-Seq_HELA_Human3.53579529
8EST1_17652178_ChIP-ChIP_JURKAT_Human3.42353285
9PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.35412370
10CREB1_15753290_ChIP-ChIP_HEK293T_Human3.35370888
11E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.28761207
12ETS1_20019798_ChIP-Seq_JURKAT_Human3.16451627
13NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.89986294
14* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.88828668
15CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.84855592
16MYC_19030024_ChIP-ChIP_MESCs_Mouse2.60714356
17RXR_22158963_ChIP-Seq_LIVER_Mouse2.54017172
18HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.52592334
19EGR1_23403033_ChIP-Seq_LIVER_Mouse2.51106269
20CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.50723820
21* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.42742235
22DCP1A_22483619_ChIP-Seq_HELA_Human2.37432533
23CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.36317726
24* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.35988299
25PPARA_22158963_ChIP-Seq_LIVER_Mouse2.30627694
26HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.30482055
27VDR_23849224_ChIP-Seq_CD4+_Human2.23012649
28SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.21446345
29SRF_21415370_ChIP-Seq_HL-1_Mouse2.19381696
30NELFA_20434984_ChIP-Seq_ESCs_Mouse2.14883008
31PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.10384356
32* XRN2_22483619_ChIP-Seq_HELA_Human2.07545273
33E2F4_17652178_ChIP-ChIP_JURKAT_Human2.02361236
34FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.93119400
35ELF1_17652178_ChIP-ChIP_JURKAT_Human1.91541737
36FOXP3_21729870_ChIP-Seq_TREG_Human1.91249461
37POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.88372393
38GABP_19822575_ChIP-Seq_HepG2_Human1.87915406
39YY1_21170310_ChIP-Seq_MESCs_Mouse1.86772611
40THAP11_20581084_ChIP-Seq_MESCs_Mouse1.77446007
41HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.75316458
42TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.74996049
43CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.71790324
44PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.70398551
45NANOG_18555785_ChIP-Seq_MESCs_Mouse1.67101946
46* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.63824574
47ELK1_19687146_ChIP-ChIP_HELA_Human1.58880554
48LXR_22158963_ChIP-Seq_LIVER_Mouse1.57193351
49TTF2_22483619_ChIP-Seq_HELA_Human1.55037137
50FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.53074897
51STAT3_1855785_ChIP-Seq_MESCs_Mouse1.51778836
52MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.50496856
53AR_21909140_ChIP-Seq_LNCAP_Human1.49761779
54FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.48375004
55MYCN_18555785_ChIP-Seq_MESCs_Mouse1.46770122
56* ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.41088769
57ZFX_18555785_ChIP-Seq_MESCs_Mouse1.40550293
58* NOTCH1_21737748_ChIP-Seq_TLL_Human1.38117571
59HOXB4_20404135_ChIP-ChIP_EML_Mouse1.36867344
60BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.34269164
61KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.33325870
62DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.30571886
63POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.28202689
64MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.28032554
65* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.25204362
66CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.24677967
67ELK1_22589737_ChIP-Seq_MCF10A_Human1.24268798
68POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.20014802
69YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.19165264
70* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.18410651
71FOXM1_23109430_ChIP-Seq_U2OS_Human1.16792085
72ZNF263_19887448_ChIP-Seq_K562_Human1.15296465
73SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.14196105
74TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.13207711
75CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.12869930
76KDM5A_27292631_Chip-Seq_BREAST_Human1.12680580
77PADI4_21655091_ChIP-ChIP_MCF-7_Human1.12088151
78* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.11796414
79* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.06959425
80TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.06394907
81ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.05444410
82DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.01618865
83PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.01325648
84HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.00413606
85SOX17_20123909_ChIP-Seq_XEN_Mouse0.99572942
86E2F1_21310950_ChIP-Seq_MCF-7_Human0.97017158
87* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.96250419
88CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.95650365
89SOX2_18692474_ChIP-Seq_MEFs_Mouse0.94868634
90ELF5_23300383_ChIP-Seq_T47D_Human0.94551502
91FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.93855259
92OCT4_18692474_ChIP-Seq_MEFs_Mouse0.93479033
93CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.92908810
94* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.92359550
95MYC_18940864_ChIP-ChIP_HL60_Human0.91837605
96ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.91279380
97ESR1_15608294_ChIP-ChIP_MCF-7_Human0.89137890
98KLF4_18555785_ChIP-Seq_MESCs_Mouse0.88906915
99GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.87745514
100MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.87067643
101SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.84050681
102SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.83205552
103CTCF_18555785_ChIP-Seq_MESCs_Mouse0.80832861
104* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.80761405
105SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.78790211
106TBX5_21415370_ChIP-Seq_HL-1_Mouse0.78450337
107TFEB_21752829_ChIP-Seq_HELA_Human0.78445754
108KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.78337549
109E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.78180454
110* CIITA_25753668_ChIP-Seq_RAJI_Human0.77187013
111ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.76522576
112SOX2_18555785_ChIP-Seq_MESCs_Mouse0.76212711
113RBPJ_22232070_ChIP-Seq_NCS_Mouse0.75940026
114CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.75834206
115SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.73218251
116KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.72433777
117NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.71799621
118STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.70541046
119TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.68717342

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003806_abnormal_nucleotide_metabolis5.86128019
2MP0002139_abnormal_hepatobiliary_system5.54753137
3MP0005360_urolithiasis4.73936676
4MP0005085_abnormal_gallbladder_physiolo4.22911587
5MP0005365_abnormal_bile_salt3.87483939
6MP0003950_abnormal_plasma_membrane3.59712232
7MP0003693_abnormal_embryo_hatching3.32531274
8MP0003186_abnormal_redox_activity3.21450295
9MP0008875_abnormal_xenobiotic_pharmacok3.15389755
10MP0006036_abnormal_mitochondrial_physio2.93175210
11MP0004957_abnormal_blastocyst_morpholog2.77936471
12MP0005332_abnormal_amino_acid2.66648000
13MP0003195_calcinosis2.56967361
14MP0009379_abnormal_foot_pigmentation2.50328511
15MP0001764_abnormal_homeostasis2.29232432
16MP0009697_abnormal_copulation2.26033862
17MP0003646_muscle_fatigue2.25050220
18MP0005083_abnormal_biliary_tract2.18023583
19MP0010329_abnormal_lipoprotein_level2.09167133
20MP0003718_maternal_effect1.97249678
21MP0006035_abnormal_mitochondrial_morpho1.96550770
22MP0009840_abnormal_foam_cell1.94732549
23MP0003941_abnormal_skin_development1.84105523
24MP0005319_abnormal_enzyme/_coenzyme1.75435573
25MP0004019_abnormal_vitamin_homeostasis1.65963205
26MP0004233_abnormal_muscle_weight1.65838476
27MP0003252_abnormal_bile_duct1.63254505
28MP0002837_dystrophic_cardiac_calcinosis1.63010099
29MP0010094_abnormal_chromosome_stability1.61719344
30MP0005266_abnormal_metabolism1.56900360
31MP0005451_abnormal_body_composition1.55804147
32MP0000609_abnormal_liver_physiology1.55466008
33MP0003111_abnormal_nucleus_morphology1.53292843
34MP0008932_abnormal_embryonic_tissue1.49235125
35MP0001666_abnormal_nutrient_absorption1.47883380
36MP0003221_abnormal_cardiomyocyte_apopto1.44867892
37MP0000313_abnormal_cell_death1.44838217
38MP0003077_abnormal_cell_cycle1.42538162
39MP0005584_abnormal_enzyme/coenzyme_acti1.41789643
40MP0008007_abnormal_cellular_replicative1.40654197
41MP0005670_abnormal_white_adipose1.39340256
42MP0008058_abnormal_DNA_repair1.37681776
43MP0009643_abnormal_urine_homeostasis1.35408209
44MP0005376_homeostasis/metabolism_phenot1.29541017
45MP0002118_abnormal_lipid_homeostasis1.27411440
46MP0002877_abnormal_melanocyte_morpholog1.25848357
47MP0005330_cardiomyopathy1.25522707
48MP0000372_irregular_coat_pigmentation1.25509856
49MP0005636_abnormal_mineral_homeostasis1.23843616
50MP0005501_abnormal_skin_physiology1.23244501
51MP0003786_premature_aging1.19524016
52MP0002332_abnormal_exercise_endurance1.18138725
53MP0003011_delayed_dark_adaptation1.17998822
54MP0003191_abnormal_cellular_cholesterol1.17574867
55MP0002796_impaired_skin_barrier1.15498977
56MP0005408_hypopigmentation1.13503019
57MP0001881_abnormal_mammary_gland1.09846606
58MP0010234_abnormal_vibrissa_follicle1.08953663
59MP0002102_abnormal_ear_morphology1.08580487
60MP0000598_abnormal_liver_morphology1.08574911
61MP0002019_abnormal_tumor_incidence1.06000983
62MP0002160_abnormal_reproductive_system1.05221039
63MP0005084_abnormal_gallbladder_morpholo1.04142097
64MP0002210_abnormal_sex_determination1.04026811
65MP0004043_abnormal_pH_regulation1.03822446
66MP0008057_abnormal_DNA_replication1.02590201
67MP0004084_abnormal_cardiac_muscle1.02540923
68MP0010307_abnormal_tumor_latency1.01550746
69MP0001929_abnormal_gametogenesis0.99781296
70MP0002138_abnormal_hepatobiliary_system0.99623931
71MP0001756_abnormal_urination0.99486117
72MP0003656_abnormal_erythrocyte_physiolo0.99052513
73MP0001661_extended_life_span0.97214105
74MP0001730_embryonic_growth_arrest0.96887431
75MP0000358_abnormal_cell_content/0.95965622
76MP0001853_heart_inflammation0.94173776
77MP0002396_abnormal_hematopoietic_system0.94077117
78MP0002876_abnormal_thyroid_physiology0.93834119
79MP0008260_abnormal_autophagy0.92965430
80MP0002132_abnormal_respiratory_system0.92540458
81MP0000749_muscle_degeneration0.89667086
82MP0000750_abnormal_muscle_regeneration0.88222626
83MP0001542_abnormal_bone_strength0.87199771
84MP0002085_abnormal_embryonic_tissue0.84685070
85MP0002086_abnormal_extraembryonic_tissu0.84210248
86MP0002269_muscular_atrophy0.83958115
87MP0008469_abnormal_protein_level0.81098546
88MP0005395_other_phenotype0.80520470
89MP0008995_early_reproductive_senescence0.79686498
90MP0002163_abnormal_gland_morphology0.78463576
91MP0009763_increased_sensitivity_to0.77811711
92MP0005666_abnormal_adipose_tissue0.77702682
93MP0004215_abnormal_myocardial_fiber0.77189007
94MP0005389_reproductive_system_phenotype0.76983775
95MP0002084_abnormal_developmental_patter0.76276836
96MP0001216_abnormal_epidermal_layer0.75492641
97MP0008789_abnormal_olfactory_epithelium0.75424377
98MP0000627_abnormal_mammary_gland0.73835045
99MP0000653_abnormal_sex_gland0.73571057
100MP0009053_abnormal_anal_canal0.72874873
101MP0009672_abnormal_birth_weight0.72806107
102MP0005384_cellular_phenotype0.71829958
103MP0001145_abnormal_male_reproductive0.71576080
104MP0003315_abnormal_perineum_morphology0.70650423
105MP0004036_abnormal_muscle_relaxation0.70055217
106MP0001727_abnormal_embryo_implantation0.69073753
107MP0002060_abnormal_skin_morphology0.69068535
108MP0003724_increased_susceptibility_to0.68251344
109MP0001919_abnormal_reproductive_system0.67207873
110MP0009642_abnormal_blood_homeostasis0.67014464
111MP0003868_abnormal_feces_composition0.67011650
112MP0005410_abnormal_fertilization0.66918282
113MP0002971_abnormal_brown_adipose0.66232976
114MP0005165_increased_susceptibility_to0.66175968
115MP0003699_abnormal_female_reproductive0.65800892
116MP0000762_abnormal_tongue_morphology0.64840730
117MP0000490_abnormal_crypts_of0.63681301
118MP0009333_abnormal_splenocyte_physiolog0.63306971
119MP0003984_embryonic_growth_retardation0.63100526
120MP0001697_abnormal_embryo_size0.62178616
121MP0003567_abnormal_fetal_cardiomyocyte0.61856567
122MP0002088_abnormal_embryonic_growth/wei0.61846408
123MP0001873_stomach_inflammation0.61834268
124MP0003123_paternal_imprinting0.61214470
125MP0001672_abnormal_embryogenesis/_devel0.60715672
126MP0005380_embryogenesis_phenotype0.60715672
127MP0001544_abnormal_cardiovascular_syste0.60619967
128MP0005385_cardiovascular_system_phenoty0.60619967
129MP0002080_prenatal_lethality0.60098014
130MP0002078_abnormal_glucose_homeostasis0.59976300
131MP0010352_gastrointestinal_tract_polyps0.59846100
132MP0000747_muscle_weakness0.59156943
133MP0008873_increased_physiological_sensi0.58970803
134MP0004782_abnormal_surfactant_physiolog0.57969027
135MP0005535_abnormal_body_temperature0.57312761
136MP0000350_abnormal_cell_proliferation0.57200458
137MP0001119_abnormal_female_reproductive0.55694465
138MP0000343_altered_response_to0.54800772
139MP0004130_abnormal_muscle_cell0.53898684
140MP0002970_abnormal_white_adipose0.53588724
141MP0010030_abnormal_orbit_morphology0.53574113
142MP0010771_integument_phenotype0.52938740
143MP0002006_tumorigenesis0.52381113
144MP0005621_abnormal_cell_physiology0.51723618
145MP0001529_abnormal_vocalization0.51556117
146MP0004185_abnormal_adipocyte_glucose0.51466649
147MP0009765_abnormal_xenobiotic_induced0.50392727
148MP0002972_abnormal_cardiac_muscle0.50222995

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.67278435
2Hepatic necrosis (HP:0002605)4.53431719
3Acute encephalopathy (HP:0006846)4.52940468
4Abnormal mitochondria in muscle tissue (HP:0008316)4.40133184
5Cerebral edema (HP:0002181)4.30300158
6Abnormality of glycolysis (HP:0004366)4.19144345
7Increased serum pyruvate (HP:0003542)4.19144345
8Mitochondrial inheritance (HP:0001427)4.16174237
9Hepatocellular necrosis (HP:0001404)4.13881430
10Abnormality of aromatic amino acid family metabolism (HP:0004338)4.06381387
11Increased CSF lactate (HP:0002490)4.01559004
12Hypobetalipoproteinemia (HP:0003563)3.92027227
13Hyperglycinemia (HP:0002154)3.83074238
14Progressive macrocephaly (HP:0004481)3.78138681
15Hyperglycinuria (HP:0003108)3.67627484
16Abnormality of monocarboxylic acid metabolism (HP:0010996)3.55290550
17Lethargy (HP:0001254)3.50180401
18Hyperammonemia (HP:0001987)3.47305034
19Abnormality of glycine metabolism (HP:0010895)3.46545793
20Abnormality of serine family amino acid metabolism (HP:0010894)3.46545793
21Lipid accumulation in hepatocytes (HP:0006561)3.44564465
22Abnormality of dicarboxylic acid metabolism (HP:0010995)3.41611278
23Dicarboxylic aciduria (HP:0003215)3.41611278
24Increased serum lactate (HP:0002151)3.40443609
25Intrahepatic cholestasis (HP:0001406)3.37030702
26Lactic acidosis (HP:0003128)3.35982609
27Hypoglycemic coma (HP:0001325)3.32510886
28Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.31753419
29Decreased activity of mitochondrial respiratory chain (HP:0008972)3.31753419
30Abnormality of fatty-acid metabolism (HP:0004359)3.30350333
31Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.25987854
32Increased hepatocellular lipid droplets (HP:0006565)3.24601995
33Aplastic anemia (HP:0001915)3.22090625
34Abnormality of the anterior horn cell (HP:0006802)3.11135024
35Degeneration of anterior horn cells (HP:0002398)3.11135024
363-Methylglutaconic aciduria (HP:0003535)3.11092999
37Type I transferrin isoform profile (HP:0003642)3.11044362
38Abnormality of serum amino acid levels (HP:0003112)3.10676066
39Nausea (HP:0002018)3.10460512
40Rough bone trabeculation (HP:0100670)3.07818909
41Sparse eyelashes (HP:0000653)3.02549403
42Respiratory failure (HP:0002878)3.01486395
43Increased muscle lipid content (HP:0009058)3.00996316
44Abnormality of placental membranes (HP:0011409)2.97989022
45Amniotic constriction ring (HP:0009775)2.97989022
46Increased intramyocellular lipid droplets (HP:0012240)2.94256236
47Xanthomatosis (HP:0000991)2.92025170
48CNS demyelination (HP:0007305)2.91886081
49Progressive muscle weakness (HP:0003323)2.89768385
50Prolonged partial thromboplastin time (HP:0003645)2.89005087
51Generalized aminoaciduria (HP:0002909)2.87547936
52Reduced antithrombin III activity (HP:0001976)2.85130169
53Abnormality of pyrimidine metabolism (HP:0004353)2.85016983
54Hypolipoproteinemia (HP:0010981)2.82879524
55Exercise intolerance (HP:0003546)2.82489879
56Renal Fanconi syndrome (HP:0001994)2.82444325
57Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.79787438
58Glycosuria (HP:0003076)2.76202010
59Abnormality of urine glucose concentration (HP:0011016)2.76202010
60Abnormality of methionine metabolism (HP:0010901)2.71897929
61Proximal tubulopathy (HP:0000114)2.70451069
62Ketosis (HP:0001946)2.70104958
63Abnormality of aspartate family amino acid metabolism (HP:0010899)2.66537728
64Long foot (HP:0001833)2.63399361
65Chromosomal breakage induced by crosslinking agents (HP:0003221)2.62966534
66Multiple enchondromatosis (HP:0005701)2.61643986
67Abnormality of the preputium (HP:0100587)2.61534600
68Chromsome breakage (HP:0040012)2.60049496
69Neoplasm of the adrenal gland (HP:0100631)2.56070553
70Birth length less than 3rd percentile (HP:0003561)2.56002150
71Deep venous thrombosis (HP:0002625)2.54860878
72Abnormal glycosylation (HP:0012345)2.53457448
73Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.53457448
74Abnormal protein N-linked glycosylation (HP:0012347)2.53457448
75Abnormal protein glycosylation (HP:0012346)2.53457448
76Vomiting (HP:0002013)2.51743300
77Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.51268838
78Hyperlipoproteinemia (HP:0010980)2.51108484
79Rhabdomyolysis (HP:0003201)2.48045076
80Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.46587340
81Premature ovarian failure (HP:0008209)2.45707339
82Metabolic acidosis (HP:0001942)2.45370012
83Cerebral hypomyelination (HP:0006808)2.44422002
84Abnormal trabecular bone morphology (HP:0100671)2.38786432
85Methylmalonic aciduria (HP:0012120)2.37473392
86Pancytopenia (HP:0001876)2.35000765
87Abnormality of alanine metabolism (HP:0010916)2.33205144
88Hyperalaninemia (HP:0003348)2.33205144
89Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.33205144
90Breast hypoplasia (HP:0003187)2.32659914
91Abnormality of sulfur amino acid metabolism (HP:0004339)2.30860123
92Trismus (HP:0000211)2.29896878
93Macrocytic anemia (HP:0001972)2.27768052
94Ketoacidosis (HP:0001993)2.26420758
95Reduced subcutaneous adipose tissue (HP:0003758)2.25542758
96Delayed CNS myelination (HP:0002188)2.25348354
97Oral leukoplakia (HP:0002745)2.24201008
98Testicular atrophy (HP:0000029)2.24113787
99Leukodystrophy (HP:0002415)2.21844718
100Abnormal gallbladder physiology (HP:0012438)2.20957101
101Cholecystitis (HP:0001082)2.20957101
102Palpitations (HP:0001962)2.20444921
103Meckel diverticulum (HP:0002245)2.19505288
104Hypoalphalipoproteinemia (HP:0003233)2.17647875
105Respiratory difficulties (HP:0002880)2.15841131
106Microvesicular hepatic steatosis (HP:0001414)2.15107771
107Exertional dyspnea (HP:0002875)2.14735435
108Hyperphosphaturia (HP:0003109)2.13687697
109Opisthotonus (HP:0002179)2.13151608
110Ragged-red muscle fibers (HP:0003200)2.12387393
111Abnormality of nucleobase metabolism (HP:0010932)2.11829508
112Fat malabsorption (HP:0002630)2.11434464
113Abnormality of cells of the erythroid lineage (HP:0012130)2.11412600
114Abnormalities of placenta or umbilical cord (HP:0001194)2.10076512
115Abnormality of the ileum (HP:0001549)2.09985724
116Megaloblastic anemia (HP:0001889)2.09910512
117Reticulocytopenia (HP:0001896)2.08695158
118Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.06204982
119Abnormal number of erythroid precursors (HP:0012131)2.05212920
120Optic disc pallor (HP:0000543)2.04864189
121Abnormality of glutamine family amino acid metabolism (HP:0010902)2.04759853
122Myoglobinuria (HP:0002913)2.02413411
123Hyperbilirubinemia (HP:0002904)2.01926032
124Carpal bone hypoplasia (HP:0001498)2.00119526
125X-linked dominant inheritance (HP:0001423)1.98299354
126Hypokinesia (HP:0002375)1.96713888
127Brushfield spots (HP:0001088)1.96143790
128Congenital ichthyosiform erythroderma (HP:0007431)1.96067945
129Gliosis (HP:0002171)1.95795778
130Diastasis recti (HP:0001540)1.92305217
131Emotional lability (HP:0000712)1.92233414
132Secondary amenorrhea (HP:0000869)1.90951171
133Progressive external ophthalmoplegia (HP:0000590)1.90364775
134Postnatal microcephaly (HP:0005484)1.88346593
135Death in infancy (HP:0001522)1.84596529
136Horseshoe kidney (HP:0000085)1.84314186
137Abnormality of renal resorption (HP:0011038)1.80527675
138Ureteral duplication (HP:0000073)1.77436834
139Posterior subcapsular cataract (HP:0007787)1.75624714
140Myelodysplasia (HP:0002863)1.75062993
141Abnormality of the umbilical cord (HP:0010881)1.74332362
142Squamous cell carcinoma (HP:0002860)1.73861575
143Abnormality of chromosome stability (HP:0003220)1.73564337
144Microretrognathia (HP:0000308)1.71172789
145Nemaline bodies (HP:0003798)1.70559930
146Aplasia/Hypoplasia of the sacrum (HP:0008517)1.70536663

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK165.06099132
2BUB14.24399555
3BCKDK4.11917574
4NME24.11621415
5EIF2AK14.11543320
6VRK23.47254198
7WEE13.46361143
8EIF2AK32.27363755
9PBK2.13170771
10SRPK12.07763590
11TSSK62.01174620
12NME11.97583142
13PDK31.89760189
14PDK41.89760189
15BRSK21.85994750
16PLK41.82195883
17NEK11.76750430
18TLK11.75833872
19TESK21.73414553
20MYLK1.67230113
21STK38L1.66398121
22PDK21.63400445
23KDR1.59049568
24IRAK31.51901134
25NEK91.50186059
26VRK11.48063098
27TRIM281.45795221
28SCYL21.38229023
29TTK1.36434565
30MKNK21.31194770
31ZAK1.31125568
32PIM21.30979623
33EPHA21.29999460
34MAP3K111.27567234
35PLK11.26344567
36ABL21.24835444
37OBSCN1.17797481
38BRAF1.14054295
39TESK11.13720589
40MAP3K31.13185336
41AURKA1.09562462
42ARAF1.08752086
43PRKG21.08389569
44STK101.06699247
45PLK31.01364290
46CDC71.01269918
47AURKB0.97739489
48MST40.95972688
49MKNK10.94188029
50LIMK10.93827069
51ACVR1B0.93593539
52BMPR1B0.89706937
53AKT30.86977778
54EIF2AK20.85280126
55BRSK10.82472004
56PIK3CG0.77061367
57NUAK10.75287755
58CSNK2A10.72576606
59CAMK2G0.70569020
60DYRK30.68179209
61DAPK30.66826283
62RPS6KA40.64244716
63CSNK2A20.63786736
64CDK90.63784436
65MAP3K120.62247453
66CDK70.60434387
67MAP2K30.59823838
68CDK80.59817515
69PAK40.59616550
70ERBB40.58623202
71CCNB10.58535191
72NEK20.58319535
73MAP3K80.58310017
74STK240.58092338
75ALK0.54802610
76PRKCI0.54544872
77RAF10.52998849
78ERBB30.52806379
79DYRK20.51520204
80CHEK20.49172186
81STK40.46820171
82MAPKAPK30.46142619
83AKT20.45254114
84CSNK1G30.45231456
85MAP3K50.44992819
86PINK10.44560835
87FLT30.44184730
88MAP3K90.43959014
89SMG10.43532398
90PIM10.42804208
91ATM0.41733520
92ILK0.41407805
93CAMK2D0.41290577
94TAOK20.40326540
95PLK20.40245049
96CAMK2B0.38110100
97MOS0.37949106
98CSNK1G10.37867937
99PAK10.37258132
100CLK10.36984707
101MST1R0.36613789
102LRRK20.34990890
103STK390.34441379
104RPS6KB20.33671621
105ATR0.33544828
106CDK40.33468199
107IRAK10.33465819
108ERN10.33162258
109CSNK1A1L0.32433198
110NEK60.32229335
111GRK60.32166793
112SIK30.29531144
113BMPR20.29223743
114LATS20.29069841
115MUSK0.28967153
116CSNK1E0.28407526
117RPS6KA50.27861291
118IRAK40.26853609
119MAPK40.26782613
120CDK10.26295483
121GRK70.25755885
122MAPK110.25318755
123MAPKAPK50.25129323
124STK30.23983946
125BCR0.23505030
126WNK30.20389946
127PIK3CA0.20380951
128CHEK10.19253208
129MET0.16805747
130DAPK10.16599647
131MARK30.16168053
132TGFBR10.16101791

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030503.43579888
2Oxidative phosphorylation_Homo sapiens_hsa001902.70495715
3Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.63785990
4Ribosome_Homo sapiens_hsa030102.59329242
5Parkinsons disease_Homo sapiens_hsa050122.41932315
6Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.35897903
7Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.15939782
82-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.14941767
9Propanoate metabolism_Homo sapiens_hsa006402.12911728
10RNA polymerase_Homo sapiens_hsa030202.12010020
11Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.11826461
12Primary bile acid biosynthesis_Homo sapiens_hsa001202.08375868
13Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.08256777
14Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.98803581
15Fatty acid degradation_Homo sapiens_hsa000711.91815509
16DNA replication_Homo sapiens_hsa030301.85766921
17Carbon metabolism_Homo sapiens_hsa012001.79793855
18Huntingtons disease_Homo sapiens_hsa050161.78409983
19Pyruvate metabolism_Homo sapiens_hsa006201.73437552
20One carbon pool by folate_Homo sapiens_hsa006701.70152878
21Folate biosynthesis_Homo sapiens_hsa007901.68182323
22Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.67440509
23Peroxisome_Homo sapiens_hsa041461.61507831
24Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.61443654
25Pyrimidine metabolism_Homo sapiens_hsa002401.60228426
26Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.60081385
27Cysteine and methionine metabolism_Homo sapiens_hsa002701.59291885
28Tryptophan metabolism_Homo sapiens_hsa003801.55994494
29Alzheimers disease_Homo sapiens_hsa050101.53525691
30Mismatch repair_Homo sapiens_hsa034301.53244723
31Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.50834342
32Butanoate metabolism_Homo sapiens_hsa006501.49854658
33Biosynthesis of amino acids_Homo sapiens_hsa012301.46056924
34Drug metabolism - other enzymes_Homo sapiens_hsa009831.45006911
35Protein export_Homo sapiens_hsa030601.43002576
36Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.41521312
37Vitamin B6 metabolism_Homo sapiens_hsa007501.41497443
38Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.40353468
39Pentose and glucuronate interconversions_Homo sapiens_hsa000401.39508795
40Fatty acid elongation_Homo sapiens_hsa000621.36501974
41Arginine biosynthesis_Homo sapiens_hsa002201.35434594
42Sulfur relay system_Homo sapiens_hsa041221.33779469
43Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.32080074
44Selenocompound metabolism_Homo sapiens_hsa004501.32031475
45Fatty acid metabolism_Homo sapiens_hsa012121.31478966
46Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.31175861
47Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.29538592
48Glutathione metabolism_Homo sapiens_hsa004801.24220715
49Sulfur metabolism_Homo sapiens_hsa009201.23683045
50Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.22179751
51Phenylalanine metabolism_Homo sapiens_hsa003601.19927335
52Chemical carcinogenesis_Homo sapiens_hsa052041.18173107
53Nucleotide excision repair_Homo sapiens_hsa034201.16366409
54beta-Alanine metabolism_Homo sapiens_hsa004101.13516491
55Cyanoamino acid metabolism_Homo sapiens_hsa004601.11813606
56Tyrosine metabolism_Homo sapiens_hsa003501.11079632
57RNA transport_Homo sapiens_hsa030131.10234848
58Pentose phosphate pathway_Homo sapiens_hsa000301.07654494
59Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.06376005
60Spliceosome_Homo sapiens_hsa030401.06057257
61Complement and coagulation cascades_Homo sapiens_hsa046101.04616162
62Homologous recombination_Homo sapiens_hsa034401.02522194
63PPAR signaling pathway_Homo sapiens_hsa033201.01112537
64Histidine metabolism_Homo sapiens_hsa003400.96932396
65Retinol metabolism_Homo sapiens_hsa008300.91357165
66Metabolic pathways_Homo sapiens_hsa011000.88414704
67Base excision repair_Homo sapiens_hsa034100.88200954
68Steroid hormone biosynthesis_Homo sapiens_hsa001400.88102151
69Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.88045986
70Arginine and proline metabolism_Homo sapiens_hsa003300.87936124
71mRNA surveillance pathway_Homo sapiens_hsa030150.83882174
72Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.81754730
73Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.79991037
74Fructose and mannose metabolism_Homo sapiens_hsa000510.77767918
75Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.77004395
76Purine metabolism_Homo sapiens_hsa002300.74617274
77Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.73309181
78Cardiac muscle contraction_Homo sapiens_hsa042600.72383862
79Fat digestion and absorption_Homo sapiens_hsa049750.69806053
80Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.67699973
81Steroid biosynthesis_Homo sapiens_hsa001000.65353986
82Nitrogen metabolism_Homo sapiens_hsa009100.64242150
83Starch and sucrose metabolism_Homo sapiens_hsa005000.63876269
84Basal transcription factors_Homo sapiens_hsa030220.63221055
85Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.60002447
86Oocyte meiosis_Homo sapiens_hsa041140.59697856
87RNA degradation_Homo sapiens_hsa030180.58585924
88N-Glycan biosynthesis_Homo sapiens_hsa005100.57009285
89Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.53789101
90Galactose metabolism_Homo sapiens_hsa000520.52755716
91Collecting duct acid secretion_Homo sapiens_hsa049660.52078723
92Caffeine metabolism_Homo sapiens_hsa002320.46771594
93Vitamin digestion and absorption_Homo sapiens_hsa049770.45184316
94Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.44788186
95Vibrio cholerae infection_Homo sapiens_hsa051100.44561744
96Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.43747109
97Cell cycle_Homo sapiens_hsa041100.43413892
98Non-homologous end-joining_Homo sapiens_hsa034500.40093334
99Maturity onset diabetes of the young_Homo sapiens_hsa049500.39814347
100Staphylococcus aureus infection_Homo sapiens_hsa051500.39375868
101Legionellosis_Homo sapiens_hsa051340.38508859
102Arachidonic acid metabolism_Homo sapiens_hsa005900.37730632
103Glycerolipid metabolism_Homo sapiens_hsa005610.34222893
104Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.31731442
105Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.31253400
106Fanconi anemia pathway_Homo sapiens_hsa034600.29972870
107Linoleic acid metabolism_Homo sapiens_hsa005910.25907113
108Regulation of autophagy_Homo sapiens_hsa041400.24451663
109Epstein-Barr virus infection_Homo sapiens_hsa051690.24354554
110Mineral absorption_Homo sapiens_hsa049780.22541651
111Herpes simplex infection_Homo sapiens_hsa051680.22094840
112Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.19445732
113Systemic lupus erythematosus_Homo sapiens_hsa053220.18638005
114p53 signaling pathway_Homo sapiens_hsa041150.18348280
115Shigellosis_Homo sapiens_hsa051310.17246547
116SNARE interactions in vesicular transport_Homo sapiens_hsa041300.14208215
117Viral carcinogenesis_Homo sapiens_hsa052030.13196497
118Apoptosis_Homo sapiens_hsa042100.10748139
119Circadian rhythm_Homo sapiens_hsa047100.07505020
120HTLV-I infection_Homo sapiens_hsa051660.06464886

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