Rank | Gene Set | Z-score |
---|---|---|
1 | righting reflex (GO:0060013) | 6.86792794 |
2 | * auditory receptor cell differentiation (GO:0042491) | 6.45952722 |
3 | DNA strand renaturation (GO:0000733) | 5.71667927 |
4 | face development (GO:0060324) | 5.17845857 |
5 | behavioral response to ethanol (GO:0048149) | 4.97831777 |
6 | negative regulation of organelle assembly (GO:1902116) | 4.76923475 |
7 | mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337) | 4.63226512 |
8 | positive regulation of keratinocyte differentiation (GO:0045618) | 4.57485479 |
9 | cranial nerve morphogenesis (GO:0021602) | 4.49261755 |
10 | pentose metabolic process (GO:0019321) | 4.46420175 |
11 | glucocorticoid biosynthetic process (GO:0006704) | 4.13813766 |
12 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 4.08770757 |
13 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.95942171 |
14 | cochlea morphogenesis (GO:0090103) | 3.87846532 |
15 | N-acetylglucosamine metabolic process (GO:0006044) | 3.85528314 |
16 | toxin transport (GO:1901998) | 3.83850827 |
17 | * hair cell differentiation (GO:0035315) | 3.78809537 |
18 | positive regulation of amino acid transport (GO:0051957) | 3.75999087 |
19 | metanephric mesenchyme development (GO:0072075) | 3.68129409 |
20 | short-term memory (GO:0007614) | 3.63784134 |
21 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 3.57056277 |
22 | inositol metabolic process (GO:0006020) | 3.55362822 |
23 | eyelid development in camera-type eye (GO:0061029) | 3.51081108 |
24 | reflex (GO:0060004) | 3.42797063 |
25 | positive regulation of vesicle fusion (GO:0031340) | 3.41820326 |
26 | negative regulation of establishment of protein localization to plasma membrane (GO:0090005) | 3.40470409 |
27 | positive regulation of epidermal cell differentiation (GO:0045606) | 3.36235847 |
28 | * inner ear receptor cell differentiation (GO:0060113) | 3.35203904 |
29 | notochord development (GO:0030903) | 3.33586277 |
30 | negative regulation of keratinocyte proliferation (GO:0010839) | 3.31428754 |
31 | keratinocyte development (GO:0003334) | 3.29410088 |
32 | cardiac right ventricle morphogenesis (GO:0003215) | 3.27788038 |
33 | head development (GO:0060322) | 3.26623500 |
34 | regulation of DNA damage checkpoint (GO:2000001) | 3.26573451 |
35 | kidney mesenchyme development (GO:0072074) | 3.25374209 |
36 | cell migration in hindbrain (GO:0021535) | 3.24683879 |
37 | single strand break repair (GO:0000012) | 3.22916429 |
38 | sulfation (GO:0051923) | 3.22329885 |
39 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339 | 3.21542536 |
40 | positive regulation of protein dephosphorylation (GO:0035307) | 3.20261957 |
41 | negative regulation of leukocyte chemotaxis (GO:0002689) | 3.16671698 |
42 | glycine transport (GO:0015816) | 3.16404916 |
43 | mesenchymal to epithelial transition (GO:0060231) | 3.16164255 |
44 | cranial nerve development (GO:0021545) | 3.12051986 |
45 | pattern specification involved in kidney development (GO:0061004) | 3.11660722 |
46 | establishment of apical/basal cell polarity (GO:0035089) | 3.11231006 |
47 | adult feeding behavior (GO:0008343) | 3.07366743 |
48 | pathway-restricted SMAD protein phosphorylation (GO:0060389) | 3.07356537 |
49 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla | 3.05110915 |
50 | nephron tubule formation (GO:0072079) | 3.02196125 |
51 | glucosamine-containing compound metabolic process (GO:1901071) | 3.01168665 |
52 | sympathetic nervous system development (GO:0048485) | 3.00753179 |
53 | establishment or maintenance of monopolar cell polarity (GO:0061339) | 2.98346811 |
54 | establishment of monopolar cell polarity (GO:0061162) | 2.98346811 |
55 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 2.95268273 |
56 | myelin assembly (GO:0032288) | 2.93818010 |
57 | cell differentiation involved in metanephros development (GO:0072202) | 2.93738549 |
58 | proline biosynthetic process (GO:0006561) | 2.88548442 |
59 | cellular response to ATP (GO:0071318) | 2.86198377 |
60 | urogenital system development (GO:0001655) | 2.85693359 |
61 | inner ear morphogenesis (GO:0042472) | 2.83667499 |
62 | neuron cell-cell adhesion (GO:0007158) | 2.83311790 |
63 | neuron fate specification (GO:0048665) | 2.79652963 |
64 | glucocorticoid metabolic process (GO:0008211) | 2.78223706 |
65 | regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307) | 2.76322691 |
66 | piRNA metabolic process (GO:0034587) | 2.74633536 |
67 | opioid receptor signaling pathway (GO:0038003) | 2.73823929 |
68 | * sensory perception of sound (GO:0007605) | 2.73572486 |
69 | * sensory perception of mechanical stimulus (GO:0050954) | 2.72368251 |
70 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.71894922 |
71 | locomotory exploration behavior (GO:0035641) | 2.71024042 |
72 | * mechanoreceptor differentiation (GO:0042490) | 2.68139783 |
73 | pharyngeal system development (GO:0060037) | 2.67742053 |
74 | cellular response to cadmium ion (GO:0071276) | 2.67730697 |
75 | proximal/distal pattern formation (GO:0009954) | 2.67137531 |
76 | regulation of cAMP-dependent protein kinase activity (GO:2000479) | 2.66154261 |
77 | kidney morphogenesis (GO:0060993) | 2.61718156 |
78 | postsynaptic membrane organization (GO:0001941) | 2.61665667 |
79 | mesenchymal cell differentiation involved in renal system development (GO:2001012) | 2.61219458 |
80 | mesenchymal cell differentiation involved in kidney development (GO:0072161) | 2.61219458 |
81 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 2.61177040 |
82 | dendritic spine morphogenesis (GO:0060997) | 2.60933481 |
83 | negative regulation of execution phase of apoptosis (GO:1900118) | 2.60733550 |
84 | synaptic vesicle exocytosis (GO:0016079) | 2.59886737 |
85 | positive regulation of metanephros development (GO:0072216) | 2.59178744 |
86 | negative regulation of granulocyte differentiation (GO:0030853) | 2.55636848 |
87 | ventricular system development (GO:0021591) | 2.52788946 |
88 | positive regulation of branching involved in ureteric bud morphogenesis (GO:0090190) | 2.51044780 |
89 | negative regulation of Ras GTPase activity (GO:0034261) | 2.50404705 |
90 | positive regulation of mesonephros development (GO:0061213) | 2.49927908 |
91 | diterpenoid biosynthetic process (GO:0016102) | 2.49484658 |
92 | startle response (GO:0001964) | 2.48945368 |
93 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 2.48712840 |
94 | RNA destabilization (GO:0050779) | 2.48301153 |
95 | regulation of non-canonical Wnt signaling pathway (GO:2000050) | 2.46941688 |
96 | negative regulation of protein localization to cell surface (GO:2000009) | 2.45471600 |
97 | lateral sprouting from an epithelium (GO:0060601) | 2.44650553 |
98 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 2.43552291 |
99 | adenosine metabolic process (GO:0046085) | 2.43447802 |
100 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 2.43224365 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.83137965 |
2 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 3.19499888 |
3 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.82138749 |
4 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.61209990 |
5 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.53840871 |
6 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.39307153 |
7 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.37801074 |
8 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.37801074 |
9 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.36119075 |
10 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.24657751 |
11 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.22958860 |
12 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.22461094 |
13 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.12226116 |
14 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.10320626 |
15 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.05789873 |
16 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.05150725 |
17 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.99464295 |
18 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.99430534 |
19 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.92634520 |
20 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.91769752 |
21 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.91639822 |
22 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.90152521 |
23 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.87759970 |
24 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.84820836 |
25 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.81575878 |
26 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.81575878 |
27 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.81575878 |
28 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.80190283 |
29 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.78993062 |
30 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.78710388 |
31 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.78696947 |
32 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.74784395 |
33 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.63946096 |
34 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.55678855 |
35 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.54392614 |
36 | * ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.47655541 |
37 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.41315106 |
38 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.41315106 |
39 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.41296992 |
40 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.40826792 |
41 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.38018299 |
42 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.36851226 |
43 | VDR_22108803_ChIP-Seq_LS180_Human | 1.34084066 |
44 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.28644855 |
45 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.28259179 |
46 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.28067293 |
47 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.27764153 |
48 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.26764609 |
49 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.24870320 |
50 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.24599621 |
51 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.24097394 |
52 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.21814651 |
53 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.21184490 |
54 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.20451616 |
55 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.20011641 |
56 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.19549252 |
57 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.18384296 |
58 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 1.17887921 |
59 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.16469653 |
60 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.14739574 |
61 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.14560188 |
62 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.13760995 |
63 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.13669545 |
64 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 1.13234301 |
65 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.11710142 |
66 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.10870326 |
67 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.09910546 |
68 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.09218258 |
69 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.09184420 |
70 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.06601880 |
71 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.06004272 |
72 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.05322663 |
73 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.05179544 |
74 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.04776603 |
75 | ESRRB_18555785_Chip-Seq_ESCs_Mouse | 1.04244567 |
76 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.03926532 |
77 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.02568571 |
78 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.02124170 |
79 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.01945596 |
80 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.01727407 |
81 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 1.01451757 |
82 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.00298627 |
83 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.99853198 |
84 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.99662938 |
85 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.99064456 |
86 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 0.98947976 |
87 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.97104847 |
88 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 0.96788386 |
89 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 0.96099316 |
90 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 0.95651908 |
91 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.95257917 |
92 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.94437982 |
93 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.93387202 |
94 | KDM2B_26808549_Chip-Seq_K562_Human | 0.93197750 |
95 | ETV1_20927104_ChIP-Seq_GIST48_Human | 0.92614386 |
96 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.91826521 |
97 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.91590037 |
98 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.91315496 |
99 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 0.90945888 |
100 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.90751259 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003879_abnormal_hair_cell | 4.77981328 |
2 | MP0001485_abnormal_pinna_reflex | 4.75401835 |
3 | MP0002102_abnormal_ear_morphology | 4.70792236 |
4 | MP0005377_hearing/vestibular/ear_phenot | 3.84360347 |
5 | MP0003878_abnormal_ear_physiology | 3.84360347 |
6 | * MP0000026_abnormal_inner_ear | 2.98285598 |
7 | * MP0001963_abnormal_hearing_physiology | 2.91630951 |
8 | * MP0001486_abnormal_startle_reflex | 2.84799057 |
9 | MP0008995_early_reproductive_senescence | 2.83708823 |
10 | MP0005645_abnormal_hypothalamus_physiol | 2.81516808 |
11 | MP0009278_abnormal_bone_marrow | 2.67675869 |
12 | MP0000566_synostosis | 2.51716612 |
13 | MP0003938_abnormal_ear_development | 2.45494350 |
14 | MP0005623_abnormal_meninges_morphology | 2.41656987 |
15 | MP0006072_abnormal_retinal_apoptosis | 2.40147000 |
16 | MP0000383_abnormal_hair_follicle | 2.02044873 |
17 | MP0002249_abnormal_larynx_morphology | 1.99976674 |
18 | MP0002938_white_spotting | 1.92816243 |
19 | MP0000013_abnormal_adipose_tissue | 1.87425067 |
20 | * MP0004742_abnormal_vestibular_system | 1.86702040 |
21 | MP0002139_abnormal_hepatobiliary_system | 1.74294642 |
22 | MP0003890_abnormal_embryonic-extraembry | 1.65326304 |
23 | MP0000049_abnormal_middle_ear | 1.63505957 |
24 | MP0003942_abnormal_urinary_system | 1.59959883 |
25 | MP0010678_abnormal_skin_adnexa | 1.54999619 |
26 | MP0005248_abnormal_Harderian_gland | 1.54127232 |
27 | MP0002751_abnormal_autonomic_nervous | 1.50021413 |
28 | MP0004885_abnormal_endolymph | 1.48894721 |
29 | MP0004019_abnormal_vitamin_homeostasis | 1.47813904 |
30 | MP0002653_abnormal_ependyma_morphology | 1.38092707 |
31 | MP0001968_abnormal_touch/_nociception | 1.35648262 |
32 | MP0010368_abnormal_lymphatic_system | 1.35573031 |
33 | MP0005451_abnormal_body_composition | 1.31056259 |
34 | MP0005187_abnormal_penis_morphology | 1.30362853 |
35 | MP0002184_abnormal_innervation | 1.28376921 |
36 | MP0003786_premature_aging | 1.28340399 |
37 | MP0008789_abnormal_olfactory_epithelium | 1.23857625 |
38 | MP0002697_abnormal_eye_size | 1.23438814 |
39 | MP0004859_abnormal_synaptic_plasticity | 1.23086166 |
40 | * MP0002752_abnormal_somatic_nervous | 1.22769472 |
41 | MP0005670_abnormal_white_adipose | 1.22689061 |
42 | MP0002733_abnormal_thermal_nociception | 1.20828043 |
43 | MP0000534_abnormal_ureter_morphology | 1.17195838 |
44 | MP0005085_abnormal_gallbladder_physiolo | 1.16997705 |
45 | MP0000579_abnormal_nail_morphology | 1.14945461 |
46 | MP0000613_abnormal_salivary_gland | 1.12641695 |
47 | MP0005174_abnormal_tail_pigmentation | 1.11311471 |
48 | MP0001340_abnormal_eyelid_morphology | 1.10442297 |
49 | MP0003045_fibrosis | 1.09927434 |
50 | MP0010030_abnormal_orbit_morphology | 1.07451158 |
51 | MP0000647_abnormal_sebaceous_gland | 1.06372477 |
52 | MP0005253_abnormal_eye_physiology | 1.05489734 |
53 | MP0002098_abnormal_vibrissa_morphology | 1.05484957 |
54 | MP0005423_abnormal_somatic_nervous | 1.04709067 |
55 | MP0000762_abnormal_tongue_morphology | 1.03500937 |
56 | MP0001970_abnormal_pain_threshold | 1.03486024 |
57 | MP0003453_abnormal_keratinocyte_physiol | 1.01538004 |
58 | MP0003137_abnormal_impulse_conducting | 1.00982421 |
59 | MP0009780_abnormal_chondrocyte_physiolo | 1.00670357 |
60 | MP0002116_abnormal_craniofacial_bone | 1.00312363 |
61 | MP0009745_abnormal_behavioral_response | 0.98294972 |
62 | MP0001986_abnormal_taste_sensitivity | 0.96015383 |
63 | MP0001286_abnormal_eye_development | 0.95067132 |
64 | MP0005171_absent_coat_pigmentation | 0.93426328 |
65 | MP0002796_impaired_skin_barrier | 0.92795617 |
66 | * MP0002067_abnormal_sensory_capabilities | 0.91516936 |
67 | MP0000465_gastrointestinal_hemorrhage | 0.91131038 |
68 | MP0002572_abnormal_emotion/affect_behav | 0.90208701 |
69 | MP0000778_abnormal_nervous_system | 0.90104252 |
70 | MP0002557_abnormal_social/conspecific_i | 0.89598562 |
71 | MP0001501_abnormal_sleep_pattern | 0.88675531 |
72 | * MP0002272_abnormal_nervous_system | 0.87509494 |
73 | MP0003787_abnormal_imprinting | 0.87199945 |
74 | MP0003635_abnormal_synaptic_transmissio | 0.84794450 |
75 | MP0010352_gastrointestinal_tract_polyps | 0.81906208 |
76 | MP0002111_abnormal_tail_morphology | 0.81694592 |
77 | MP0004270_analgesia | 0.81138486 |
78 | MP0008877_abnormal_DNA_methylation | 0.80734157 |
79 | MP0002282_abnormal_trachea_morphology | 0.80542543 |
80 | MP0002063_abnormal_learning/memory/cond | 0.79863018 |
81 | MP0002233_abnormal_nose_morphology | 0.78374904 |
82 | MP0000462_abnormal_digestive_system | 0.76711548 |
83 | * MP0002882_abnormal_neuron_morphology | 0.73020690 |
84 | MP0009046_muscle_twitch | 0.70380445 |
85 | MP0005195_abnormal_posterior_eye | 0.69587232 |
86 | MP0005391_vision/eye_phenotype | 0.68259249 |
87 | MP0000631_abnormal_neuroendocrine_gland | 0.67580103 |
88 | MP0005365_abnormal_bile_salt | 0.67314331 |
89 | MP0003385_abnormal_body_wall | 0.67240938 |
90 | MP0002064_seizures | 0.67096028 |
91 | MP0001664_abnormal_digestion | 0.66854371 |
92 | * MP0002066_abnormal_motor_capabilities/c | 0.66447895 |
93 | MP0005394_taste/olfaction_phenotype | 0.66392509 |
94 | MP0005499_abnormal_olfactory_system | 0.66392509 |
95 | MP0008874_decreased_physiological_sensi | 0.66181005 |
96 | MP0003935_abnormal_craniofacial_develop | 0.65618691 |
97 | MP0002277_abnormal_respiratory_mucosa | 0.65211816 |
98 | MP0002932_abnormal_joint_morphology | 0.65122501 |
99 | MP0000955_abnormal_spinal_cord | 0.63069409 |
100 | MP0003868_abnormal_feces_composition | 0.62878686 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Duplicated collecting system (HP:0000081) | 5.85063354 |
2 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 5.57120495 |
3 | Abnormality of the renal collecting system (HP:0004742) | 5.48851192 |
4 | Intestinal atresia (HP:0011100) | 5.23375862 |
5 | Lip pit (HP:0100267) | 4.77821401 |
6 | Chromsome breakage (HP:0040012) | 4.49387300 |
7 | Unilateral renal agenesis (HP:0000122) | 4.07803473 |
8 | Reticulocytopenia (HP:0001896) | 3.93012953 |
9 | Mixed hearing impairment (HP:0000410) | 3.78913370 |
10 | Bilateral sensorineural hearing impairment (HP:0008619) | 3.75954902 |
11 | Hypoplasia of the fovea (HP:0007750) | 3.68935302 |
12 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 3.68935302 |
13 | Bilateral microphthalmos (HP:0007633) | 3.66883044 |
14 | Fused cervical vertebrae (HP:0002949) | 3.53612807 |
15 | Congenital stationary night blindness (HP:0007642) | 3.36484083 |
16 | Renal agenesis (HP:0000104) | 3.35442739 |
17 | Abnormality of DNA repair (HP:0003254) | 3.29882685 |
18 | Abnormality of dentin (HP:0010299) | 3.15235186 |
19 | Gastrointestinal atresia (HP:0002589) | 3.10704170 |
20 | Duplication of thumb phalanx (HP:0009942) | 3.01497050 |
21 | Absent radius (HP:0003974) | 2.95199772 |
22 | Morphological abnormality of the middle ear (HP:0008609) | 2.91266474 |
23 | Ectopic anus (HP:0004397) | 2.90868640 |
24 | Upper limb muscle weakness (HP:0003484) | 2.88662614 |
25 | Absent thumb (HP:0009777) | 2.87896168 |
26 | Abnormality of pyrimidine metabolism (HP:0004353) | 2.86683501 |
27 | Aplasia involving forearm bones (HP:0009822) | 2.86149747 |
28 | Absent forearm bone (HP:0003953) | 2.86149747 |
29 | Increased IgM level (HP:0003496) | 2.80664776 |
30 | Hypochromic microcytic anemia (HP:0004840) | 2.80621003 |
31 | Squamous cell carcinoma (HP:0002860) | 2.72996045 |
32 | Ureteral duplication (HP:0000073) | 2.72450985 |
33 | Abnormality of the fovea (HP:0000493) | 2.57597040 |
34 | Severe Myopia (HP:0011003) | 2.54064090 |
35 | Annular pancreas (HP:0001734) | 2.48287652 |
36 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 2.47168043 |
37 | Aplasia/Hypoplasia of the macula (HP:0008059) | 2.41865221 |
38 | Lower limb amyotrophy (HP:0007210) | 2.37249997 |
39 | Facial shape deformation (HP:0011334) | 2.36149061 |
40 | Potter facies (HP:0002009) | 2.36149061 |
41 | Alacrima (HP:0000522) | 2.35649142 |
42 | Mesomelia (HP:0003027) | 2.34209042 |
43 | Osteomalacia (HP:0002749) | 2.32882318 |
44 | Abnormality of the ileum (HP:0001549) | 2.30951226 |
45 | Chorioretinal atrophy (HP:0000533) | 2.26771213 |
46 | Ectopic kidney (HP:0000086) | 2.26677276 |
47 | Distal lower limb amyotrophy (HP:0008944) | 2.25682600 |
48 | Coronal craniosynostosis (HP:0004440) | 2.25564801 |
49 | Distal lower limb muscle weakness (HP:0009053) | 2.24262785 |
50 | Overfolded helix (HP:0000396) | 2.24051717 |
51 | Congenital sensorineural hearing impairment (HP:0008527) | 2.23050983 |
52 | Intrahepatic cholestasis (HP:0001406) | 2.20695953 |
53 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.17559735 |
54 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.17559735 |
55 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.14581509 |
56 | Horseshoe kidney (HP:0000085) | 2.13936317 |
57 | Meckel diverticulum (HP:0002245) | 2.11830404 |
58 | Vertebral fusion (HP:0002948) | 2.09258482 |
59 | Anteriorly placed anus (HP:0001545) | 2.07999754 |
60 | Hyperthyroidism (HP:0000836) | 2.07591016 |
61 | Turricephaly (HP:0000262) | 2.04622430 |
62 | Esophageal atresia (HP:0002032) | 2.03720067 |
63 | Papillary thyroid carcinoma (HP:0002895) | 2.01842118 |
64 | Aplasia/Hypoplasia affecting the retina (HP:0008061) | 2.01422477 |
65 | Abnormally folded helix (HP:0008544) | 2.01298461 |
66 | Prostate neoplasm (HP:0100787) | 2.00784064 |
67 | Renal hypoplasia (HP:0000089) | 1.99668474 |
68 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 1.98982556 |
69 | Abnormality of the duodenum (HP:0002246) | 1.98830936 |
70 | Short thumb (HP:0009778) | 1.96893429 |
71 | Bicornuate uterus (HP:0000813) | 1.96408268 |
72 | Epiphyseal dysplasia (HP:0002656) | 1.95000322 |
73 | Abnormality of the preputium (HP:0100587) | 1.94775810 |
74 | Anophthalmia (HP:0000528) | 1.91601184 |
75 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.87863298 |
76 | Hypoplastic ischia (HP:0003175) | 1.87191538 |
77 | Atelectasis (HP:0100750) | 1.85524451 |
78 | Dysautonomia (HP:0002459) | 1.82041694 |
79 | Decreased number of peripheral myelinated nerve fibers (HP:0003380) | 1.80484132 |
80 | Morphological abnormality of the inner ear (HP:0011390) | 1.79892117 |
81 | Febrile seizures (HP:0002373) | 1.79286643 |
82 | Hepatoblastoma (HP:0002884) | 1.78824210 |
83 | Cupped ear (HP:0000378) | 1.78249127 |
84 | Abnormality of the pubic bones (HP:0003172) | 1.77140454 |
85 | Decreased motor nerve conduction velocity (HP:0003431) | 1.76367987 |
86 | Exotropia (HP:0000577) | 1.75465076 |
87 | Down-sloping shoulders (HP:0200021) | 1.74533754 |
88 | Progressive sensorineural hearing impairment (HP:0000408) | 1.70588600 |
89 | Aplasia/Hypoplasia of the earlobes (HP:0009906) | 1.70155010 |
90 | Acute lymphatic leukemia (HP:0006721) | 1.68519854 |
91 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.68313909 |
92 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.68313909 |
93 | Facial cleft (HP:0002006) | 1.68140042 |
94 | Abnormality of the antihelix (HP:0009738) | 1.67574210 |
95 | Abnormal hemoglobin (HP:0011902) | 1.67542508 |
96 | Skin pits (HP:0100276) | 1.67387483 |
97 | Parakeratosis (HP:0001036) | 1.67166884 |
98 | Myocardial infarction (HP:0001658) | 1.66681512 |
99 | Abnormality of the corticospinal tract (HP:0002492) | 1.66415224 |
100 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.64576306 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DDR2 | 5.57481251 |
2 | NTRK3 | 3.84604968 |
3 | MAPK15 | 3.00501630 |
4 | CASK | 2.85399042 |
5 | GRK1 | 2.53936847 |
6 | KSR1 | 2.51521310 |
7 | PAK6 | 2.50701776 |
8 | PDGFRA | 2.35350466 |
9 | LATS2 | 2.30292695 |
10 | LATS1 | 2.19040675 |
11 | EIF2AK2 | 2.11127116 |
12 | ADRBK2 | 2.09511304 |
13 | UHMK1 | 2.03747023 |
14 | ICK | 1.81135279 |
15 | PIK3CG | 1.79852237 |
16 | DYRK1B | 1.79022407 |
17 | PINK1 | 1.65174311 |
18 | TNIK | 1.59141581 |
19 | KSR2 | 1.56322446 |
20 | FGR | 1.56229371 |
21 | CDC42BPA | 1.55725372 |
22 | MARK1 | 1.50972086 |
23 | DYRK2 | 1.40744893 |
24 | HIPK2 | 1.38979473 |
25 | IRAK2 | 1.38296078 |
26 | WNK4 | 1.32184370 |
27 | PAK3 | 1.30860058 |
28 | EPHB1 | 1.28719293 |
29 | MAP3K6 | 1.24575487 |
30 | TRPM7 | 1.20492029 |
31 | CLK1 | 1.20178992 |
32 | YES1 | 1.17720022 |
33 | EPHA3 | 1.15881791 |
34 | RIPK1 | 1.15768434 |
35 | EPHB2 | 1.11738889 |
36 | PHKG2 | 1.09823525 |
37 | PHKG1 | 1.09823525 |
38 | NME1 | 1.04741479 |
39 | MARK3 | 1.01292635 |
40 | FER | 1.00105362 |
41 | ALK | 0.98059001 |
42 | MAP3K9 | 0.94686583 |
43 | ERBB4 | 0.93539931 |
44 | EPHA2 | 0.91468330 |
45 | BMPR1B | 0.90542192 |
46 | PRKD2 | 0.89932467 |
47 | PRPF4B | 0.88152903 |
48 | TYRO3 | 0.87241191 |
49 | STK39 | 0.86975098 |
50 | PRKAA1 | 0.85278600 |
51 | WNK1 | 0.85248627 |
52 | CAMK2A | 0.83300097 |
53 | MAP2K7 | 0.81750003 |
54 | SIK2 | 0.81280639 |
55 | STK3 | 0.79792541 |
56 | PAK2 | 0.79564703 |
57 | MATK | 0.78241563 |
58 | CSK | 0.78001545 |
59 | ERBB3 | 0.75417616 |
60 | NTRK2 | 0.70769940 |
61 | PKN1 | 0.70178466 |
62 | FGFR4 | 0.69412772 |
63 | MAP3K2 | 0.69155500 |
64 | CDK7 | 0.66979902 |
65 | ADRBK1 | 0.65135223 |
66 | MAP3K4 | 0.64650378 |
67 | GSK3A | 0.59373469 |
68 | PRKAA2 | 0.57465220 |
69 | TTK | 0.56012636 |
70 | DAPK1 | 0.53308181 |
71 | SGK1 | 0.50527500 |
72 | PDGFRB | 0.49989524 |
73 | NTRK1 | 0.47593892 |
74 | PRKD3 | 0.46898523 |
75 | MKNK2 | 0.45659607 |
76 | PTK2 | 0.44303479 |
77 | RAF1 | 0.44249339 |
78 | CSNK1G1 | 0.44181895 |
79 | CAMK2B | 0.43349083 |
80 | STK16 | 0.42625924 |
81 | HCK | 0.42514391 |
82 | BLK | 0.42078471 |
83 | DAPK2 | 0.40567236 |
84 | CSNK1A1L | 0.40485346 |
85 | IRAK1 | 0.40137305 |
86 | CDK5 | 0.39405153 |
87 | SIK1 | 0.37255644 |
88 | PRKCE | 0.37216648 |
89 | PRKCZ | 0.37131726 |
90 | MAP2K1 | 0.36604072 |
91 | CSNK1E | 0.35980192 |
92 | ERBB2 | 0.34911491 |
93 | MAPK13 | 0.34757251 |
94 | BCR | 0.33480704 |
95 | PRKCG | 0.32213358 |
96 | SRC | 0.32182892 |
97 | INSRR | 0.31321698 |
98 | CAMK2D | 0.30698378 |
99 | STK11 | 0.30450622 |
100 | PIM1 | 0.30381796 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 4.25587090 |
2 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 3.01927922 |
3 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 2.68369084 |
4 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 2.68160985 |
5 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.59770245 |
6 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 2.46155378 |
7 | Histidine metabolism_Homo sapiens_hsa00340 | 2.04724688 |
8 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.91922535 |
9 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.76780060 |
10 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.74678348 |
11 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.60949792 |
12 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.59941948 |
13 | Taste transduction_Homo sapiens_hsa04742 | 1.59379227 |
14 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 1.57378541 |
15 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 1.56430241 |
16 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.50282726 |
17 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.43305089 |
18 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.37339521 |
19 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.35365495 |
20 | Phototransduction_Homo sapiens_hsa04744 | 1.32928874 |
21 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.30329769 |
22 | ABC transporters_Homo sapiens_hsa02010 | 1.29746631 |
23 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.26109215 |
24 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.24296012 |
25 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.23825600 |
26 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.22383940 |
27 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.21080735 |
28 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.19890417 |
29 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.18171329 |
30 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.17918937 |
31 | Morphine addiction_Homo sapiens_hsa05032 | 1.17889440 |
32 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.15694157 |
33 | Axon guidance_Homo sapiens_hsa04360 | 1.14237213 |
34 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.13460832 |
35 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.08579111 |
36 | GABAergic synapse_Homo sapiens_hsa04727 | 1.05567519 |
37 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.04774798 |
38 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.03627607 |
39 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.02668416 |
40 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.02383646 |
41 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.01314855 |
42 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.98336054 |
43 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.98038104 |
44 | Lysine degradation_Homo sapiens_hsa00310 | 0.97962382 |
45 | Viral myocarditis_Homo sapiens_hsa05416 | 0.95603207 |
46 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.92201969 |
47 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.92126441 |
48 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.85483817 |
49 | Nicotine addiction_Homo sapiens_hsa05033 | 0.84408258 |
50 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.83964465 |
51 | Insulin secretion_Homo sapiens_hsa04911 | 0.83811901 |
52 | Cocaine addiction_Homo sapiens_hsa05030 | 0.83355679 |
53 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.83272229 |
54 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.82899395 |
55 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.81682630 |
56 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.81280749 |
57 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.80357805 |
58 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.80220140 |
59 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.77943271 |
60 | Melanogenesis_Homo sapiens_hsa04916 | 0.77779926 |
61 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.75496357 |
62 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.75494829 |
63 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.74316097 |
64 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.74177996 |
65 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.73663303 |
66 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.73464853 |
67 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.70846024 |
68 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.70687090 |
69 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.70610554 |
70 | Olfactory transduction_Homo sapiens_hsa04740 | 0.68926746 |
71 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.67956810 |
72 | Long-term depression_Homo sapiens_hsa04730 | 0.67114211 |
73 | Focal adhesion_Homo sapiens_hsa04510 | 0.66963050 |
74 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.66734528 |
75 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.62626878 |
76 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.62399249 |
77 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.62141467 |
78 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.61532633 |
79 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.61178699 |
80 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.60866417 |
81 | Tight junction_Homo sapiens_hsa04530 | 0.59896718 |
82 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.58397879 |
83 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.54800888 |
84 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.54230782 |
85 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.53220429 |
86 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.52492316 |
87 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.52097841 |
88 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.51994152 |
89 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.50789387 |
90 | Colorectal cancer_Homo sapiens_hsa05210 | 0.50323119 |
91 | Prion diseases_Homo sapiens_hsa05020 | 0.49337687 |
92 | Circadian entrainment_Homo sapiens_hsa04713 | 0.49278567 |
93 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.48447341 |
94 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.47539268 |
95 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.45558122 |
96 | Circadian rhythm_Homo sapiens_hsa04710 | 0.45383884 |
97 | Retinol metabolism_Homo sapiens_hsa00830 | 0.44463183 |
98 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.41007551 |
99 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.40997018 |
100 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.40648192 |