

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 8.82592388 |
| 2 | negative regulation of vascular permeability (GO:0043116) | 8.52267272 |
| 3 | regulation of mononuclear cell migration (GO:0071675) | 8.51084013 |
| 4 | regulation of feeding behavior (GO:0060259) | 8.06696690 |
| 5 | negative regulation of axon guidance (GO:1902668) | 8.01547154 |
| 6 | regulation of catecholamine metabolic process (GO:0042069) | 7.81398511 |
| 7 | regulation of dopamine metabolic process (GO:0042053) | 7.81398511 |
| 8 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 7.11899334 |
| 9 | negative regulation of smooth muscle cell migration (GO:0014912) | 7.11885943 |
| 10 | regulation of monocyte chemotaxis (GO:0090025) | 6.44442289 |
| 11 | detection of light stimulus involved in sensory perception (GO:0050962) | 6.13394848 |
| 12 | detection of light stimulus involved in visual perception (GO:0050908) | 6.13394848 |
| 13 | positive regulation of amino acid transport (GO:0051957) | 5.95228555 |
| 14 | cell migration involved in sprouting angiogenesis (GO:0002042) | 5.76253557 |
| 15 | regulation of dopamine secretion (GO:0014059) | 5.71648221 |
| 16 | positive regulation of heart rate (GO:0010460) | 5.67802443 |
| 17 | regulation of axon guidance (GO:1902667) | 5.59130410 |
| 18 | membrane hyperpolarization (GO:0060081) | 5.44411897 |
| 19 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 5.17877161 |
| 20 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 5.09582413 |
| 21 | motor neuron axon guidance (GO:0008045) | 4.99714366 |
| 22 | synaptic transmission, glutamatergic (GO:0035249) | 4.86613940 |
| 23 | response to morphine (GO:0043278) | 4.80694939 |
| 24 | hyperosmotic response (GO:0006972) | 4.62170128 |
| 25 | response to isoquinoline alkaloid (GO:0014072) | 4.56778456 |
| 26 | negative chemotaxis (GO:0050919) | 4.46894364 |
| 27 | mating behavior (GO:0007617) | 4.43657971 |
| 28 | retinal ganglion cell axon guidance (GO:0031290) | 4.28451034 |
| 29 | negative regulation of axon extension (GO:0030517) | 4.23754947 |
| 30 | neuron-neuron synaptic transmission (GO:0007270) | 4.14338935 |
| 31 | protein localization to synapse (GO:0035418) | 4.13650622 |
| 32 | response to salt stress (GO:0009651) | 4.05160785 |
| 33 | positive regulation of heart contraction (GO:0045823) | 4.04632568 |
| 34 | positive regulation of smooth muscle contraction (GO:0045987) | 4.00214513 |
| 35 | regulation of neutrophil chemotaxis (GO:0090022) | 3.97932875 |
| 36 | regulation of neutrophil migration (GO:1902622) | 3.97932875 |
| 37 | neuromuscular process controlling posture (GO:0050884) | 3.93244953 |
| 38 | apoptotic process involved in development (GO:1902742) | 3.89200672 |
| 39 | blood vessel endothelial cell migration (GO:0043534) | 3.69893670 |
| 40 | positive regulation of blood pressure (GO:0045777) | 3.61357625 |
| 41 | detection of temperature stimulus (GO:0016048) | 3.60954317 |
| 42 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 3.60893844 |
| 43 | regulation of vascular permeability (GO:0043114) | 3.56195792 |
| 44 | negative regulation of leukocyte migration (GO:0002686) | 3.49693966 |
| 45 | startle response (GO:0001964) | 3.49677483 |
| 46 | regulation of lamellipodium assembly (GO:0010591) | 3.41201159 |
| 47 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 3.37254982 |
| 48 | synaptic vesicle endocytosis (GO:0048488) | 3.36217133 |
| 49 | response to cocaine (GO:0042220) | 3.34168981 |
| 50 | behavioral response to pain (GO:0048266) | 3.27983176 |
| 51 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 3.18202484 |
| 52 | detection of temperature stimulus involved in sensory perception of pain (GO:0050965) | 3.14941862 |
| 53 | detection of temperature stimulus involved in sensory perception (GO:0050961) | 3.14941862 |
| 54 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 3.14866187 |
| 55 | synaptic vesicle maturation (GO:0016188) | 3.14476330 |
| 56 | cellular potassium ion homeostasis (GO:0030007) | 3.12393845 |
| 57 | positive regulation of muscle contraction (GO:0045933) | 3.12302287 |
| 58 | iron coordination entity transport (GO:1901678) | 3.12062646 |
| 59 | regulation of amino acid transport (GO:0051955) | 3.10723506 |
| 60 | negative regulation of chemotaxis (GO:0050922) | 3.08063465 |
| 61 | glutamate receptor signaling pathway (GO:0007215) | 3.05529481 |
| 62 | righting reflex (GO:0060013) | 3.04910491 |
| 63 | axon extension (GO:0048675) | 3.04784636 |
| 64 | regulation of postsynaptic membrane potential (GO:0060078) | 3.03957782 |
| 65 | synaptic transmission, cholinergic (GO:0007271) | 3.03749909 |
| 66 | regulation of synaptic vesicle exocytosis (GO:2000300) | 3.02448196 |
| 67 | regulation of granulocyte chemotaxis (GO:0071622) | 3.00887277 |
| 68 | regulation of transmission of nerve impulse (GO:0051969) | 2.93350902 |
| 69 | synaptic vesicle exocytosis (GO:0016079) | 2.92536424 |
| 70 | negative regulation of cytokine-mediated signaling pathway (GO:0001960) | 2.88348656 |
| 71 | negative regulation of endothelial cell migration (GO:0010596) | 2.86421871 |
| 72 | retinal rod cell development (GO:0046548) | 2.85836227 |
| 73 | neuron projection extension (GO:1990138) | 2.81171869 |
| 74 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 2.79952025 |
| 75 | N-acetylglucosamine metabolic process (GO:0006044) | 2.77964266 |
| 76 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 2.77215701 |
| 77 | positive regulation of organic acid transport (GO:0032892) | 2.75102511 |
| 78 | regulation of smooth muscle cell migration (GO:0014910) | 2.73034073 |
| 79 | regulation of catecholamine secretion (GO:0050433) | 2.69979344 |
| 80 | negative regulation of small GTPase mediated signal transduction (GO:0051058) | 2.68903476 |
| 81 | membrane depolarization (GO:0051899) | 2.67617250 |
| 82 | regulation of lamellipodium organization (GO:1902743) | 2.65896364 |
| 83 | regulation of synaptic transmission, GABAergic (GO:0032228) | 2.63545605 |
| 84 | regulation of amine transport (GO:0051952) | 2.62725076 |
| 85 | fat-soluble vitamin biosynthetic process (GO:0042362) | 2.55917195 |
| 86 | regulation of cofactor metabolic process (GO:0051193) | 2.55647741 |
| 87 | regulation of coenzyme metabolic process (GO:0051196) | 2.55647741 |
| 88 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 2.53379885 |
| 89 | negative regulation of response to cytokine stimulus (GO:0060761) | 2.48326252 |
| 90 | innervation (GO:0060384) | 2.48157425 |
| 91 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.46781902 |
| 92 | response to pheromone (GO:0019236) | 17.9317141 |
| 93 | tachykinin receptor signaling pathway (GO:0007217) | 15.5787026 |
| 94 | positive regulation of uterine smooth muscle contraction (GO:0070474) | 13.4938926 |
| 95 | hyperosmotic salinity response (GO:0042538) | 13.0070159 |
| 96 | negative regulation of leukocyte chemotaxis (GO:0002689) | 12.3814126 |
| 97 | regulation of chemokine-mediated signaling pathway (GO:0070099) | 11.4115149 |
| 98 | axon extension involved in axon guidance (GO:0048846) | 11.3137135 |
| 99 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 11.3137135 |
| 100 | regulation of uterine smooth muscle contraction (GO:0070472) | 10.8608104 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 7.71673388 |
| 2 | GBX2_23144817_ChIP-Seq_PC3_Human | 4.35948095 |
| 3 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 4.20203854 |
| 4 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 3.36769332 |
| 5 | TAF15_26573619_Chip-Seq_HEK293_Human | 3.30595378 |
| 6 | ZNF263_19887448_ChIP-Seq_K562_Human | 3.15704111 |
| 7 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 3.11399102 |
| 8 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.07572883 |
| 9 | VDR_22108803_ChIP-Seq_LS180_Human | 2.89834867 |
| 10 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.68043423 |
| 11 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.64618291 |
| 12 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.61936537 |
| 13 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.56340862 |
| 14 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.47442227 |
| 15 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.47442227 |
| 16 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.45238438 |
| 17 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.30876113 |
| 18 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.29940535 |
| 19 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.29259331 |
| 20 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.21535428 |
| 21 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.14310813 |
| 22 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.00125123 |
| 23 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.99509198 |
| 24 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.95237740 |
| 25 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.93860847 |
| 26 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.91550949 |
| 27 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.88110529 |
| 28 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.86509473 |
| 29 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.86454685 |
| 30 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.84272288 |
| 31 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.79191401 |
| 32 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.74541227 |
| 33 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.70402947 |
| 34 | P300_19829295_ChIP-Seq_ESCs_Human | 1.70126364 |
| 35 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.62331164 |
| 36 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.61021251 |
| 37 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.60533736 |
| 38 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.56832766 |
| 39 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.54744691 |
| 40 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.46972103 |
| 41 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.45303243 |
| 42 | TP53_16413492_ChIP-PET_HCT116_Human | 1.39751095 |
| 43 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.39191702 |
| 44 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.38301459 |
| 45 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.35495393 |
| 46 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.35148951 |
| 47 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.33123534 |
| 48 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.32961377 |
| 49 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.30297052 |
| 50 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.26788511 |
| 51 | GATA3_20176728_ChIP-ChIP_TSCs_Mouse | 1.26399790 |
| 52 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.19934979 |
| 53 | AR_25329375_ChIP-Seq_VCAP_Human | 1.17763460 |
| 54 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.15920686 |
| 55 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.14428221 |
| 56 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.14226104 |
| 57 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.09675963 |
| 58 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.08370687 |
| 59 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.07552237 |
| 60 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.07109743 |
| 61 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.03809827 |
| 62 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.99479804 |
| 63 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 0.99152214 |
| 64 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.99045585 |
| 65 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 0.98584866 |
| 66 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.97522666 |
| 67 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.97010571 |
| 68 | RXR_22108803_ChIP-Seq_LS180_Human | 0.96794856 |
| 69 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.96746907 |
| 70 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.96641737 |
| 71 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.96629853 |
| 72 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.95512301 |
| 73 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.94812433 |
| 74 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.94131752 |
| 75 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 0.93362306 |
| 76 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.93162175 |
| 77 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.90497276 |
| 78 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.88471870 |
| 79 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 0.86235907 |
| 80 | EWS_26573619_Chip-Seq_HEK293_Human | 0.85535135 |
| 81 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.83463833 |
| 82 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.82755753 |
| 83 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.82585201 |
| 84 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 0.82516951 |
| 85 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.81281693 |
| 86 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.81210147 |
| 87 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 0.81072035 |
| 88 | NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse | 0.80987713 |
| 89 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.79782076 |
| 90 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 0.78797658 |
| 91 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 0.78055280 |
| 92 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.77777413 |
| 93 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 0.77702827 |
| 94 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.77248902 |
| 95 | AR_19668381_ChIP-Seq_PC3_Human | 0.76753808 |
| 96 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.76217771 |
| 97 | RUNX1_26923725_Chip-Seq_HPCs_Mouse | 0.75863750 |
| 98 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.73191213 |
| 99 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.73008542 |
| 100 | STAT3_23295773_ChIP-Seq_U87_Human | 0.71998047 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002735_abnormal_chemical_nociception | 6.63256350 |
| 2 | MP0005551_abnormal_eye_electrophysiolog | 4.74475748 |
| 3 | MP0003880_abnormal_central_pattern | 4.10009181 |
| 4 | MP0010368_abnormal_lymphatic_system | 3.75508799 |
| 5 | MP0000534_abnormal_ureter_morphology | 3.58990258 |
| 6 | MP0004859_abnormal_synaptic_plasticity | 3.25743935 |
| 7 | MP0002736_abnormal_nociception_after | 3.16425874 |
| 8 | MP0003635_abnormal_synaptic_transmissio | 3.08168291 |
| 9 | MP0001968_abnormal_touch/_nociception | 3.06306927 |
| 10 | MP0002272_abnormal_nervous_system | 2.86609435 |
| 11 | MP0005423_abnormal_somatic_nervous | 2.80104581 |
| 12 | MP0004858_abnormal_nervous_system | 2.74447798 |
| 13 | MP0002090_abnormal_vision | 2.53918617 |
| 14 | MP0001486_abnormal_startle_reflex | 2.34689799 |
| 15 | MP0002064_seizures | 2.33638017 |
| 16 | MP0004510_myositis | 2.28873828 |
| 17 | MP0003950_abnormal_plasma_membrane | 2.15103781 |
| 18 | MP0002063_abnormal_learning/memory/cond | 2.14644543 |
| 19 | MP0003172_abnormal_lysosome_physiology | 1.99978647 |
| 20 | MP0004270_analgesia | 1.97390109 |
| 21 | MP0001440_abnormal_grooming_behavior | 1.97130731 |
| 22 | MP0002572_abnormal_emotion/affect_behav | 1.90342542 |
| 23 | MP0005670_abnormal_white_adipose | 1.88488406 |
| 24 | MP0003329_amyloid_beta_deposits | 1.86168287 |
| 25 | MP0001970_abnormal_pain_threshold | 1.83571979 |
| 26 | MP0003942_abnormal_urinary_system | 1.81631473 |
| 27 | MP0005253_abnormal_eye_physiology | 1.80833053 |
| 28 | MP0005623_abnormal_meninges_morphology | 1.79582137 |
| 29 | MP0005195_abnormal_posterior_eye | 1.60503910 |
| 30 | MP0009745_abnormal_behavioral_response | 1.59719312 |
| 31 | MP0004134_abnormal_chest_morphology | 1.58304531 |
| 32 | MP0008961_abnormal_basal_metabolism | 1.56121769 |
| 33 | MP0002733_abnormal_thermal_nociception | 1.54071132 |
| 34 | MP0009046_muscle_twitch | 1.52895885 |
| 35 | MP0002638_abnormal_pupillary_reflex | 1.51356545 |
| 36 | MP0003303_peritoneal_inflammation | 1.47650563 |
| 37 | MP0002067_abnormal_sensory_capabilities | 1.46287697 |
| 38 | MP0009840_abnormal_foam_cell | 1.39390695 |
| 39 | MP0003941_abnormal_skin_development | 1.39100229 |
| 40 | MP0003191_abnormal_cellular_cholesterol | 1.36290812 |
| 41 | MP0005365_abnormal_bile_salt | 1.35655005 |
| 42 | MP0006072_abnormal_retinal_apoptosis | 1.31445114 |
| 43 | MP0003279_aneurysm | 1.30852494 |
| 44 | MP0001502_abnormal_circadian_rhythm | 1.28606369 |
| 45 | MP0003633_abnormal_nervous_system | 1.26792601 |
| 46 | MP0003011_delayed_dark_adaptation | 1.23896863 |
| 47 | MP0002734_abnormal_mechanical_nocicepti | 1.19196224 |
| 48 | MP0002229_neurodegeneration | 1.17938929 |
| 49 | MP0003806_abnormal_nucleotide_metabolis | 1.16472001 |
| 50 | MP0001661_extended_life_span | 1.15935181 |
| 51 | MP0010329_abnormal_lipoprotein_level | 1.15049631 |
| 52 | MP0004885_abnormal_endolymph | 1.13368611 |
| 53 | MP0002909_abnormal_adrenal_gland | 1.12371991 |
| 54 | MP0008875_abnormal_xenobiotic_pharmacok | 1.10566862 |
| 55 | MP0002882_abnormal_neuron_morphology | 1.08082719 |
| 56 | MP0001879_abnormal_lymphatic_vessel | 1.05949265 |
| 57 | MP0000604_amyloidosis | 1.01145087 |
| 58 | MP0006276_abnormal_autonomic_nervous | 0.99681864 |
| 59 | MP0003879_abnormal_hair_cell | 0.99586209 |
| 60 | MP0003868_abnormal_feces_composition | 0.96460819 |
| 61 | MP0003631_nervous_system_phenotype | 0.95218610 |
| 62 | MP0002752_abnormal_somatic_nervous | 0.93747330 |
| 63 | MP0005360_urolithiasis | 0.92216740 |
| 64 | MP0000920_abnormal_myelination | 0.92183433 |
| 65 | MP0002066_abnormal_motor_capabilities/c | 0.91367920 |
| 66 | MP0004142_abnormal_muscle_tone | 0.88446821 |
| 67 | MP0004215_abnormal_myocardial_fiber | 0.87898115 |
| 68 | MP0002184_abnormal_innervation | 0.87067034 |
| 69 | MP0000013_abnormal_adipose_tissue | 0.86668767 |
| 70 | MP0005187_abnormal_penis_morphology | 0.82691437 |
| 71 | MP0010030_abnormal_orbit_morphology | 0.81734338 |
| 72 | MP0004145_abnormal_muscle_electrophysio | 0.81291203 |
| 73 | MP0002876_abnormal_thyroid_physiology | 0.80802967 |
| 74 | MP0002557_abnormal_social/conspecific_i | 0.80760628 |
| 75 | MP0005410_abnormal_fertilization | 0.79583972 |
| 76 | MP0002139_abnormal_hepatobiliary_system | 0.79514296 |
| 77 | MP0004811_abnormal_neuron_physiology | 0.79060298 |
| 78 | MP0005394_taste/olfaction_phenotype | 0.78581788 |
| 79 | MP0005499_abnormal_olfactory_system | 0.78581788 |
| 80 | MP0003283_abnormal_digestive_organ | 0.77699952 |
| 81 | MP0008569_lethality_at_weaning | 0.77098891 |
| 82 | MP0010386_abnormal_urinary_bladder | 0.76783585 |
| 83 | MP0000955_abnormal_spinal_cord | 0.76052138 |
| 84 | MP0008789_abnormal_olfactory_epithelium | 0.75677939 |
| 85 | MP0003634_abnormal_glial_cell | 0.73876633 |
| 86 | MP0009384_cardiac_valve_regurgitation | 0.73835903 |
| 87 | MP0005085_abnormal_gallbladder_physiolo | 0.72987550 |
| 88 | MP0004272_abnormal_basement_membrane | 0.72313238 |
| 89 | MP0000639_abnormal_adrenal_gland | 0.68542123 |
| 90 | MP0003632_abnormal_nervous_system | 0.68416111 |
| 91 | MP0005595_abnormal_vascular_smooth | 0.66910136 |
| 92 | MP0001324_abnormal_eye_pigmentation | 0.66156248 |
| 93 | MP0002108_abnormal_muscle_morphology | 0.65871564 |
| 94 | MP0001346_abnormal_lacrimal_gland | 0.65733294 |
| 95 | MP0008874_decreased_physiological_sensi | 0.64556765 |
| 96 | MP0008872_abnormal_physiological_respon | 0.64371245 |
| 97 | MP0001501_abnormal_sleep_pattern | 0.63769079 |
| 98 | MP0000631_abnormal_neuroendocrine_gland | 0.63516221 |
| 99 | MP0004924_abnormal_behavior | 0.61313992 |
| 100 | MP0005386_behavior/neurological_phenoty | 0.61313992 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Congenital stationary night blindness (HP:0007642) | 7.25120409 |
| 2 | Hypogonadotrophic hypogonadism (HP:0000044) | 5.63216061 |
| 3 | Decreased central vision (HP:0007663) | 5.57700108 |
| 4 | Cone-rod dystrophy (HP:0000548) | 5.02989215 |
| 5 | Erectile abnormalities (HP:0100639) | 4.92304761 |
| 6 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 4.70017514 |
| 7 | Abnormality of alanine metabolism (HP:0010916) | 4.70017514 |
| 8 | Hyperalaninemia (HP:0003348) | 4.70017514 |
| 9 | Breast aplasia (HP:0100783) | 4.57056607 |
| 10 | Central scotoma (HP:0000603) | 4.55239842 |
| 11 | Neoplasm of the heart (HP:0100544) | 4.42162247 |
| 12 | Septo-optic dysplasia (HP:0100842) | 4.41048166 |
| 13 | Abnormality of macular pigmentation (HP:0008002) | 4.12531395 |
| 14 | Severe visual impairment (HP:0001141) | 4.04789580 |
| 15 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 4.02908751 |
| 16 | Focal seizures (HP:0007359) | 4.01395458 |
| 17 | Aplasia/Hypoplasia of the breasts (HP:0010311) | 3.95676510 |
| 18 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 3.89551855 |
| 19 | Focal motor seizures (HP:0011153) | 3.80896992 |
| 20 | Increased cerebral lipofuscin (HP:0011813) | 3.62184015 |
| 21 | Atonic seizures (HP:0010819) | 3.61970290 |
| 22 | Febrile seizures (HP:0002373) | 3.60098081 |
| 23 | Dialeptic seizures (HP:0011146) | 3.56144020 |
| 24 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.52071745 |
| 25 | Ependymoma (HP:0002888) | 3.48185734 |
| 26 | Epileptic encephalopathy (HP:0200134) | 3.47210150 |
| 27 | Absence seizures (HP:0002121) | 3.46324298 |
| 28 | Scotoma (HP:0000575) | 3.44551579 |
| 29 | Decreased testicular size (HP:0008734) | 3.42265935 |
| 30 | Supernumerary spleens (HP:0009799) | 3.31580162 |
| 31 | Diplopia (HP:0000651) | 3.29134401 |
| 32 | Abnormality of binocular vision (HP:0011514) | 3.29134401 |
| 33 | Frequent falls (HP:0002359) | 2.94426206 |
| 34 | Abnormality of the astrocytes (HP:0100707) | 2.90567869 |
| 35 | Astrocytoma (HP:0009592) | 2.90567869 |
| 36 | Type 1 muscle fiber predominance (HP:0003803) | 2.87033544 |
| 37 | Chronic sinusitis (HP:0011109) | 2.84305248 |
| 38 | Absent septum pellucidum (HP:0001331) | 2.82580392 |
| 39 | Hyperlipoproteinemia (HP:0010980) | 2.80183611 |
| 40 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.64229989 |
| 41 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.63354514 |
| 42 | Facial shape deformation (HP:0011334) | 2.60972099 |
| 43 | Potter facies (HP:0002009) | 2.60972099 |
| 44 | Growth hormone deficiency (HP:0000824) | 2.60689268 |
| 45 | Generalized tonic-clonic seizures (HP:0002069) | 2.56584772 |
| 46 | Macular degeneration (HP:0000608) | 2.55454992 |
| 47 | Enlarged kidneys (HP:0000105) | 2.49711177 |
| 48 | Nemaline bodies (HP:0003798) | 2.46595065 |
| 49 | Abnormal drinking behavior (HP:0030082) | 2.45658532 |
| 50 | Polydipsia (HP:0001959) | 2.45658532 |
| 51 | Atelectasis (HP:0100750) | 2.45126044 |
| 52 | Rocker bottom foot (HP:0001838) | 2.44471717 |
| 53 | Abnormality of the septum pellucidum (HP:0007375) | 2.41228068 |
| 54 | Hypokinesia (HP:0002375) | 2.38253983 |
| 55 | Oral leukoplakia (HP:0002745) | 2.37076972 |
| 56 | Primary amenorrhea (HP:0000786) | 2.35103699 |
| 57 | Cholecystitis (HP:0001082) | 2.29901666 |
| 58 | Abnormal gallbladder physiology (HP:0012438) | 2.29901666 |
| 59 | Achilles tendon contracture (HP:0001771) | 2.27412941 |
| 60 | Gynecomastia (HP:0000771) | 2.26758231 |
| 61 | Spastic gait (HP:0002064) | 2.25649905 |
| 62 | Abnormality of the Achilles tendon (HP:0005109) | 2.25577585 |
| 63 | Clumsiness (HP:0002312) | 2.23106149 |
| 64 | Choroideremia (HP:0001139) | 2.19440471 |
| 65 | Hemiparesis (HP:0001269) | 2.19008269 |
| 66 | Tubulointerstitial fibrosis (HP:0005576) | 2.14536996 |
| 67 | Abolished electroretinogram (ERG) (HP:0000550) | 2.12323024 |
| 68 | Morphological abnormality of the middle ear (HP:0008609) | 2.11102879 |
| 69 | Recurrent bronchitis (HP:0002837) | 2.10949892 |
| 70 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.10790462 |
| 71 | Abnormal sex determination (HP:0012244) | 2.06831934 |
| 72 | Sex reversal (HP:0012245) | 2.06831934 |
| 73 | Status epilepticus (HP:0002133) | 1.98893472 |
| 74 | EEG with generalized epileptiform discharges (HP:0011198) | 1.95086870 |
| 75 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 1.93282870 |
| 76 | Long toe (HP:0010511) | 1.90554936 |
| 77 | Absent eyelashes (HP:0000561) | 1.89262205 |
| 78 | Epileptiform EEG discharges (HP:0011182) | 1.87939488 |
| 79 | Glioma (HP:0009733) | 1.87871337 |
| 80 | Aplastic anemia (HP:0001915) | 1.86923178 |
| 81 | Deep venous thrombosis (HP:0002625) | 1.85753323 |
| 82 | Visual hallucinations (HP:0002367) | 1.84844181 |
| 83 | Lymphangioma (HP:0100764) | 1.82731671 |
| 84 | Midline defect of the nose (HP:0004122) | 1.82482174 |
| 85 | Hypochromic microcytic anemia (HP:0004840) | 1.81694755 |
| 86 | Hemiplegia (HP:0002301) | 1.81101972 |
| 87 | Xanthomatosis (HP:0000991) | 1.77041823 |
| 88 | Abnormal eating behavior (HP:0100738) | 1.75765458 |
| 89 | Progressive visual loss (HP:0000529) | 1.72810939 |
| 90 | Abnormality of the periventricular white matter (HP:0002518) | 1.71661185 |
| 91 | Muscle fiber inclusion bodies (HP:0100299) | 1.68727516 |
| 92 | Anophthalmia (HP:0000528) | 1.68717749 |
| 93 | Oligodactyly (hands) (HP:0001180) | 1.67367337 |
| 94 | True hermaphroditism (HP:0010459) | 1.64972645 |
| 95 | Anteriorly placed anus (HP:0001545) | 1.64354158 |
| 96 | Stereotypic behavior (HP:0000733) | 1.64137954 |
| 97 | Micropenis (HP:0000054) | 1.64113623 |
| 98 | Pancreatic fibrosis (HP:0100732) | 1.63477905 |
| 99 | Absent speech (HP:0001344) | 1.62791673 |
| 100 | Polyphagia (HP:0002591) | 1.61157264 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STK38L | 5.14604140 |
| 2 | MARK1 | 4.63809196 |
| 3 | NEK1 | 4.31275824 |
| 4 | FES | 3.91823694 |
| 5 | EPHA3 | 3.77741782 |
| 6 | RIPK1 | 3.12725687 |
| 7 | STK38 | 2.96879707 |
| 8 | SIK1 | 2.77551202 |
| 9 | ERN1 | 2.49046498 |
| 10 | SIK2 | 2.19365815 |
| 11 | FER | 2.16844533 |
| 12 | PHKG2 | 1.95642931 |
| 13 | PHKG1 | 1.95642931 |
| 14 | WNK1 | 1.90731674 |
| 15 | PKN1 | 1.90025991 |
| 16 | LMTK2 | 1.76739768 |
| 17 | DYRK1A | 1.69718857 |
| 18 | CDK14 | 1.61446919 |
| 19 | MINK1 | 1.57456959 |
| 20 | CDK15 | 1.43808873 |
| 21 | MARK3 | 1.38005973 |
| 22 | CDK11A | 1.36046498 |
| 23 | CDK18 | 1.35879063 |
| 24 | PAK6 | 1.35430933 |
| 25 | DDR2 | 1.27278933 |
| 26 | NTRK1 | 1.08079556 |
| 27 | PRKAA1 | 1.07953587 |
| 28 | MAP3K12 | 1.07491877 |
| 29 | GRK1 | 1.05740516 |
| 30 | CDK5 | 1.01758310 |
| 31 | TAOK2 | 1.01662626 |
| 32 | PRKD3 | 1.01406234 |
| 33 | NTRK3 | 1.00651750 |
| 34 | ROCK2 | 0.96952519 |
| 35 | PAK3 | 0.96508799 |
| 36 | MAPK10 | 0.95183662 |
| 37 | EPHA4 | 0.94057187 |
| 38 | FGFR1 | 0.91376097 |
| 39 | SIK3 | 0.87855240 |
| 40 | CAMK2D | 0.83914416 |
| 41 | UHMK1 | 0.81058838 |
| 42 | TYK2 | 0.80968299 |
| 43 | MAPK9 | 0.80640290 |
| 44 | TAOK1 | 0.76684010 |
| 45 | DYRK1B | 0.76626596 |
| 46 | CDK19 | 0.75306050 |
| 47 | CDC42BPA | 0.74478159 |
| 48 | SGK223 | 0.73170272 |
| 49 | SGK494 | 0.73170272 |
| 50 | PRKCA | 0.67502817 |
| 51 | PTK6 | 0.65935867 |
| 52 | PRKCG | 0.63844365 |
| 53 | EGFR | 0.62693676 |
| 54 | CAMK2A | 0.61280427 |
| 55 | MAP2K4 | 0.60193243 |
| 56 | RIPK4 | 0.59654060 |
| 57 | CAMK1 | 0.59429602 |
| 58 | CSF1R | 0.58378162 |
| 59 | ADRBK1 | 0.58059226 |
| 60 | PRKCB | 0.57440377 |
| 61 | PASK | 0.57212654 |
| 62 | RPS6KA3 | 0.54506141 |
| 63 | MAPK4 | 0.54366149 |
| 64 | KSR2 | 0.51794147 |
| 65 | PRKCE | 0.51591853 |
| 66 | PDK4 | 0.49385551 |
| 67 | PDK3 | 0.49385551 |
| 68 | ERBB3 | 0.48851741 |
| 69 | GRK5 | 0.48639740 |
| 70 | FYN | 0.47398345 |
| 71 | FGR | 0.46597504 |
| 72 | SGK1 | 0.45954815 |
| 73 | TTN | 0.45041268 |
| 74 | CAMK1G | 0.42203586 |
| 75 | CAMKK1 | 0.42190046 |
| 76 | MAP3K11 | 0.40832588 |
| 77 | MATK | 0.39037385 |
| 78 | SRC | 0.35604493 |
| 79 | CSK | 0.35428797 |
| 80 | NTRK2 | 0.32616271 |
| 81 | MAP3K10 | 0.32410345 |
| 82 | PLK2 | 0.31436443 |
| 83 | FGFR4 | 0.30719524 |
| 84 | PRKACB | 0.29059261 |
| 85 | HIPK2 | 0.28540842 |
| 86 | CSNK1E | 0.28206438 |
| 87 | PRKCZ | 0.27758939 |
| 88 | MARK2 | 0.27751816 |
| 89 | ERBB2 | 0.26472471 |
| 90 | PLK3 | 0.25926891 |
| 91 | PRKDC | 0.25562659 |
| 92 | HCK | 0.24808497 |
| 93 | CAMK4 | 0.24182060 |
| 94 | MET | 0.23731173 |
| 95 | CAMK1D | 0.22349217 |
| 96 | CSNK1D | 0.21976842 |
| 97 | PRKACA | 0.21074625 |
| 98 | JAK1 | 0.19500270 |
| 99 | MAPK8 | 0.19279932 |
| 100 | MAP3K9 | 0.18275710 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Nicotine addiction_Homo sapiens_hsa05033 | 6.77899144 |
| 2 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 3.35367807 |
| 3 | GABAergic synapse_Homo sapiens_hsa04727 | 2.99807359 |
| 4 | Morphine addiction_Homo sapiens_hsa05032 | 2.77526017 |
| 5 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.64436144 |
| 6 | Circadian entrainment_Homo sapiens_hsa04713 | 2.54888017 |
| 7 | Cholinergic synapse_Homo sapiens_hsa04725 | 2.38326116 |
| 8 | Phototransduction_Homo sapiens_hsa04744 | 2.20339880 |
| 9 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.18407265 |
| 10 | Insulin secretion_Homo sapiens_hsa04911 | 2.08588285 |
| 11 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.97738244 |
| 12 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.82177227 |
| 13 | Renin secretion_Homo sapiens_hsa04924 | 1.81619529 |
| 14 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.77217220 |
| 15 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.74187399 |
| 16 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.68510098 |
| 17 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.60287466 |
| 18 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.59556137 |
| 19 | Bile secretion_Homo sapiens_hsa04976 | 1.58585041 |
| 20 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.58290361 |
| 21 | Salivary secretion_Homo sapiens_hsa04970 | 1.56825135 |
| 22 | Long-term potentiation_Homo sapiens_hsa04720 | 1.55136095 |
| 23 | Taste transduction_Homo sapiens_hsa04742 | 1.53106816 |
| 24 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.46153782 |
| 25 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.44189159 |
| 26 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.38277254 |
| 27 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.32793761 |
| 28 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.25712504 |
| 29 | Axon guidance_Homo sapiens_hsa04360 | 1.24177562 |
| 30 | Olfactory transduction_Homo sapiens_hsa04740 | 1.23380731 |
| 31 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.16291533 |
| 32 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.15338645 |
| 33 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.14069887 |
| 34 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.11899676 |
| 35 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.09418305 |
| 36 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 1.05459228 |
| 37 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.01080410 |
| 38 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.97705675 |
| 39 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.91698449 |
| 40 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.90611510 |
| 41 | Long-term depression_Homo sapiens_hsa04730 | 0.87489958 |
| 42 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.86401538 |
| 43 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.85800410 |
| 44 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.83000127 |
| 45 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.82216098 |
| 46 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.81698854 |
| 47 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.80842962 |
| 48 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.80400972 |
| 49 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.80385316 |
| 50 | Circadian rhythm_Homo sapiens_hsa04710 | 0.80097888 |
| 51 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.77297627 |
| 52 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.74295954 |
| 53 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.71973431 |
| 54 | Galactose metabolism_Homo sapiens_hsa00052 | 0.69615934 |
| 55 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.68681107 |
| 56 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.67516423 |
| 57 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.67324616 |
| 58 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.66916271 |
| 59 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.64368375 |
| 60 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.63509198 |
| 61 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.62994419 |
| 62 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.58949805 |
| 63 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.57521049 |
| 64 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.54315516 |
| 65 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.52616134 |
| 66 | Lysosome_Homo sapiens_hsa04142 | 0.51274011 |
| 67 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.49848055 |
| 68 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.49314324 |
| 69 | Carbon metabolism_Homo sapiens_hsa01200 | 0.49198001 |
| 70 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.48682877 |
| 71 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.46852750 |
| 72 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.45584256 |
| 73 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.45273787 |
| 74 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.45079116 |
| 75 | Gap junction_Homo sapiens_hsa04540 | 0.43483444 |
| 76 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.43298236 |
| 77 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.43167672 |
| 78 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.41954301 |
| 79 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.40399642 |
| 80 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.39506670 |
| 81 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.39097252 |
| 82 | Cocaine addiction_Homo sapiens_hsa05030 | 0.38947159 |
| 83 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.37270591 |
| 84 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.36866898 |
| 85 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.35428265 |
| 86 | Melanogenesis_Homo sapiens_hsa04916 | 0.33274797 |
| 87 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.32332128 |
| 88 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.32008401 |
| 89 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.30328885 |
| 90 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.29533790 |
| 91 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.29432242 |
| 92 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.27645514 |
| 93 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.26091602 |
| 94 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.25411168 |
| 95 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.24956234 |
| 96 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.24758261 |
| 97 | Platelet activation_Homo sapiens_hsa04611 | 0.24658924 |
| 98 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.23032885 |
| 99 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.21731980 |
| 100 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.20872214 |

