Rank | Gene Set | Z-score |
---|---|---|
1 | intestinal absorption (GO:0050892) | 8.12653796 |
2 | maintenance of gastrointestinal epithelium (GO:0030277) | 7.31412764 |
3 | axonemal dynein complex assembly (GO:0070286) | 7.14061590 |
4 | intestinal cholesterol absorption (GO:0030299) | 6.60487442 |
5 | flavonoid metabolic process (GO:0009812) | 6.50927304 |
6 | response to nitrosative stress (GO:0051409) | 5.86492174 |
7 | cilium or flagellum-dependent cell motility (GO:0001539) | 5.85326554 |
8 | cellular glucuronidation (GO:0052695) | 5.75711820 |
9 | epithelial structure maintenance (GO:0010669) | 5.50537454 |
10 | xenobiotic catabolic process (GO:0042178) | 5.30587429 |
11 | digestion (GO:0007586) | 5.28974686 |
12 | * glutathione derivative biosynthetic process (GO:1901687) | 5.27134557 |
13 | * glutathione derivative metabolic process (GO:1901685) | 5.27134557 |
14 | digestive system process (GO:0022600) | 5.25582716 |
15 | uronic acid metabolic process (GO:0006063) | 5.18355486 |
16 | glucuronate metabolic process (GO:0019585) | 5.18355486 |
17 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 5.15042565 |
18 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 5.01151901 |
19 | omega-hydroxylase P450 pathway (GO:0097267) | 5.00831551 |
20 | cilium movement (GO:0003341) | 4.88488116 |
21 | regulation of protein activation cascade (GO:2000257) | 4.86324755 |
22 | purine ribonucleoside bisphosphate metabolic process (GO:0034035) | 4.79778843 |
23 | 3-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427) | 4.79778843 |
24 | drug catabolic process (GO:0042737) | 4.75374345 |
25 | sulfation (GO:0051923) | 4.68716995 |
26 | motile cilium assembly (GO:0044458) | 4.60533580 |
27 | bile acid biosynthetic process (GO:0006699) | 4.57648849 |
28 | fructose metabolic process (GO:0006000) | 4.56086947 |
29 | regulation of complement activation (GO:0030449) | 4.55035302 |
30 | regulation of fibrinolysis (GO:0051917) | 4.50019540 |
31 | urea cycle (GO:0000050) | 4.49535764 |
32 | urea metabolic process (GO:0019627) | 4.49535764 |
33 | regulation of triglyceride catabolic process (GO:0010896) | 4.48061295 |
34 | negative regulation of sterol transport (GO:0032372) | 4.45684179 |
35 | negative regulation of cholesterol transport (GO:0032375) | 4.45684179 |
36 | phenylpropanoid metabolic process (GO:0009698) | 4.45157655 |
37 | protein autoprocessing (GO:0016540) | 4.40928495 |
38 | polyketide metabolic process (GO:0030638) | 4.40433492 |
39 | doxorubicin metabolic process (GO:0044598) | 4.40433492 |
40 | daunorubicin metabolic process (GO:0044597) | 4.40433492 |
41 | phospholipid efflux (GO:0033700) | 4.40133524 |
42 | vitamin transmembrane transport (GO:0035461) | 4.40034786 |
43 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 4.37163117 |
44 | sulfur amino acid catabolic process (GO:0000098) | 4.33023877 |
45 | negative regulation of fibrinolysis (GO:0051918) | 4.32075109 |
46 | complement activation, alternative pathway (GO:0006957) | 4.31403301 |
47 | cysteine metabolic process (GO:0006534) | 4.29333740 |
48 | regulation of cholesterol esterification (GO:0010872) | 4.28441288 |
49 | peptidyl-glutamic acid carboxylation (GO:0017187) | 4.27779095 |
50 | protein carboxylation (GO:0018214) | 4.27779095 |
51 | negative regulation of digestive system process (GO:0060457) | 4.25465578 |
52 | very-low-density lipoprotein particle assembly (GO:0034379) | 4.25118066 |
53 | plasma lipoprotein particle assembly (GO:0034377) | 4.24443188 |
54 | NADH metabolic process (GO:0006734) | 4.18687303 |
55 | primary alcohol metabolic process (GO:0034308) | 4.15291276 |
56 | epithelial cilium movement (GO:0003351) | 4.10940420 |
57 | regulation of cholesterol homeostasis (GO:2000188) | 4.10206867 |
58 | progesterone metabolic process (GO:0042448) | 4.09010111 |
59 | protein-lipid complex assembly (GO:0065005) | 4.07960405 |
60 | nitrogen cycle metabolic process (GO:0071941) | 4.02824019 |
61 | lipoprotein metabolic process (GO:0042157) | 3.99917820 |
62 | fat-soluble vitamin biosynthetic process (GO:0042362) | 3.99698265 |
63 | aminoglycoside antibiotic metabolic process (GO:0030647) | 3.96230207 |
64 | fibrinolysis (GO:0042730) | 3.92479316 |
65 | cholesterol efflux (GO:0033344) | 3.89538470 |
66 | negative regulation of lipase activity (GO:0060192) | 3.88587590 |
67 | angiotensin maturation (GO:0002003) | 3.87402698 |
68 | cholesterol homeostasis (GO:0042632) | 3.85935308 |
69 | high-density lipoprotein particle remodeling (GO:0034375) | 3.85346719 |
70 | sterol homeostasis (GO:0055092) | 3.83726863 |
71 | L-ascorbic acid metabolic process (GO:0019852) | 3.81121297 |
72 | reverse cholesterol transport (GO:0043691) | 3.77009616 |
73 | positive regulation of triglyceride lipase activity (GO:0061365) | 3.76671333 |
74 | positive regulation of lipoprotein lipase activity (GO:0051006) | 3.76671333 |
75 | O-glycan processing (GO:0016266) | 3.75871310 |
76 | diacylglycerol metabolic process (GO:0046339) | 3.66168123 |
77 | bile acid and bile salt transport (GO:0015721) | 3.65567642 |
78 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 3.65109877 |
79 | L-phenylalanine metabolic process (GO:0006558) | 3.65109877 |
80 | homocysteine metabolic process (GO:0050667) | 3.64894715 |
81 | oxidative demethylation (GO:0070989) | 3.63552288 |
82 | plasma lipoprotein particle remodeling (GO:0034369) | 3.61457882 |
83 | protein-lipid complex remodeling (GO:0034368) | 3.61457882 |
84 | macromolecular complex remodeling (GO:0034367) | 3.61457882 |
85 | lipoprotein transport (GO:0042953) | 3.60641821 |
86 | drug metabolic process (GO:0017144) | 3.56016490 |
87 | acylglycerol homeostasis (GO:0055090) | 3.55679966 |
88 | triglyceride homeostasis (GO:0070328) | 3.55679966 |
89 | hormone catabolic process (GO:0042447) | 3.55478854 |
90 | L-phenylalanine catabolic process (GO:0006559) | 3.50872886 |
91 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 3.50872886 |
92 | regulation of proton transport (GO:0010155) | 3.47353880 |
93 | negative regulation of blood coagulation (GO:0030195) | 3.45040070 |
94 | negative regulation of hemostasis (GO:1900047) | 3.45040070 |
95 | epoxygenase P450 pathway (GO:0019373) | 3.42571794 |
96 | diterpenoid biosynthetic process (GO:0016102) | 3.42559467 |
97 | ethanol metabolic process (GO:0006067) | 3.41817813 |
98 | blood coagulation, intrinsic pathway (GO:0007597) | 3.40136546 |
99 | exogenous drug catabolic process (GO:0042738) | 3.39457768 |
100 | phospholipid homeostasis (GO:0055091) | 3.39138538 |
101 | * xenobiotic metabolic process (GO:0006805) | 3.39119236 |
102 | alkaloid metabolic process (GO:0009820) | 3.36953451 |
103 | androgen biosynthetic process (GO:0006702) | 3.36020339 |
104 | * glutathione metabolic process (GO:0006749) | 3.35690762 |
105 | androgen metabolic process (GO:0008209) | 3.34097760 |
106 | regulation of bile acid biosynthetic process (GO:0070857) | 3.31883200 |
107 | ethanol oxidation (GO:0006069) | 3.31567614 |
108 | vitamin A metabolic process (GO:0006776) | 3.30370119 |
109 | response to iron ion (GO:0010039) | 3.27719330 |
110 | alpha-linolenic acid metabolic process (GO:0036109) | 3.25567063 |
111 | negative regulation of coagulation (GO:0050819) | 3.20930287 |
112 | positive regulation of heterotypic cell-cell adhesion (GO:0034116) | 3.20757413 |
113 | negative regulation of humoral immune response (GO:0002921) | 3.19588504 |
114 | plasma lipoprotein particle clearance (GO:0034381) | 3.16896656 |
115 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 3.16736406 |
116 | drug transport (GO:0015893) | 3.16682602 |
117 | carnitine metabolic process (GO:0009437) | 3.15996406 |
118 | regulation of humoral immune response (GO:0002920) | 3.13377328 |
119 | sterol transport (GO:0015918) | 3.13264314 |
120 | cholesterol transport (GO:0030301) | 3.13264314 |
121 | heme transport (GO:0015886) | 3.09983489 |
122 | positive regulation of fatty acid biosynthetic process (GO:0045723) | 3.09914895 |
123 | plasma lipoprotein particle organization (GO:0071827) | 3.09288317 |
124 | protein-lipid complex subunit organization (GO:0071825) | 3.07147015 |
125 | regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081) | 3.06358806 |
126 | lysine metabolic process (GO:0006553) | 3.05744984 |
127 | lysine catabolic process (GO:0006554) | 3.05744984 |
128 | benzene-containing compound metabolic process (GO:0042537) | 3.05528620 |
129 | lipid homeostasis (GO:0055088) | 3.05247869 |
130 | positive regulation of lipid catabolic process (GO:0050996) | 3.02594685 |
131 | glyoxylate metabolic process (GO:0046487) | 3.02481171 |
132 | drug transmembrane transport (GO:0006855) | 2.99595999 |
133 | thyroid hormone metabolic process (GO:0042403) | 2.98089895 |
134 | aromatic amino acid family catabolic process (GO:0009074) | 2.97944133 |
135 | positive regulation of triglyceride metabolic process (GO:0090208) | 2.97191429 |
136 | amino-acid betaine metabolic process (GO:0006577) | 2.97145096 |
137 | primary alcohol catabolic process (GO:0034310) | 2.95466207 |
138 | bile acid metabolic process (GO:0008206) | 2.94390341 |
139 | intestinal epithelial cell development (GO:0060576) | 2.92618465 |
140 | negative regulation of fatty acid metabolic process (GO:0045922) | 2.92588353 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 7.11911167 |
2 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 5.34070608 |
3 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 5.12405139 |
4 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 4.72011582 |
5 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 4.45228984 |
6 | * SOX2_27498859_Chip-Seq_STOMACH_Mouse | 4.28365787 |
7 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 4.22278299 |
8 | * EGR1_23403033_ChIP-Seq_LIVER_Mouse | 3.62558063 |
9 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 3.41719247 |
10 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 3.32623123 |
11 | * NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 3.15809809 |
12 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 3.14626832 |
13 | GATA4_25053715_ChIP-Seq_YYC3_Human | 3.02639876 |
14 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 2.84855745 |
15 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 2.78453072 |
16 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 2.76606939 |
17 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 2.57171926 |
18 | GATA6_25053715_ChIP-Seq_YYC3_Human | 2.43021592 |
19 | SOX2_20726797_ChIP-Seq_SW620_Human | 2.27107667 |
20 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 2.20408721 |
21 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 2.14293892 |
22 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 2.13847900 |
23 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.00795899 |
24 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.88400409 |
25 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.81021657 |
26 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.80509652 |
27 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.75288828 |
28 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.74924668 |
29 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.67803606 |
30 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.65768774 |
31 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.64417878 |
32 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.61381478 |
33 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.59593503 |
34 | GATA1_22025678_ChIP-Seq_K562_Human | 1.51343529 |
35 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.48980552 |
36 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.48846812 |
37 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.48482459 |
38 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.47358959 |
39 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.46471862 |
40 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.46463910 |
41 | * HNF4A_19822575_ChIP-Seq_HepG2_Human | 1.45874535 |
42 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.44887175 |
43 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.43764814 |
44 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.41849943 |
45 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.40896536 |
46 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 1.40888751 |
47 | ATF3_27146783_Chip-Seq_COLON_Human | 1.37420813 |
48 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.36355674 |
49 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.36328844 |
50 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.34227825 |
51 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.30803580 |
52 | KLF5_25053715_ChIP-Seq_YYC3_Human | 1.28504070 |
53 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.26984563 |
54 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.25563292 |
55 | * AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.23235576 |
56 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.21525948 |
57 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.20988732 |
58 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.20912919 |
59 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 1.20821422 |
60 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.20159883 |
61 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.20159883 |
62 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.19969511 |
63 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.17956979 |
64 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.16915080 |
65 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.16557398 |
66 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.16437850 |
67 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.10679611 |
68 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 1.10534124 |
69 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.10029176 |
70 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 1.09687032 |
71 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.08405553 |
72 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 1.07183673 |
73 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.06154243 |
74 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.05653835 |
75 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.04445425 |
76 | TP63_23658742_ChIP-Seq_EP156T_Human | 1.03813250 |
77 | PHF8_20622853_ChIP-Seq_HELA_Human | 1.03190885 |
78 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.02949566 |
79 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.00401447 |
80 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.99246888 |
81 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.97878293 |
82 | ETV1_20927104_ChIP-Seq_GIST48_Human | 0.95138605 |
83 | AR_20517297_ChIP-Seq_VCAP_Human | 0.94374774 |
84 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.93676184 |
85 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.93320487 |
86 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.92829045 |
87 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.92488265 |
88 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 0.91895947 |
89 | GATA1_19941826_ChIP-Seq_K562_Human | 0.91851944 |
90 | CBP_21632823_ChIP-Seq_H3396_Human | 0.90888115 |
91 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.90118114 |
92 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.89695670 |
93 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.89528258 |
94 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.89061935 |
95 | NFYA_21822215_ChIP-Seq_K562_Human | 0.86163927 |
96 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.85882422 |
97 | CBX2_22325352_ChIP-Seq_293T-Rex_Human | 0.84815876 |
98 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.84711821 |
99 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.83879810 |
100 | * EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.83336149 |
101 | GATA2_19941826_ChIP-Seq_K562_Human | 0.83218293 |
102 | CREB1_26743006_Chip-Seq_LNCaP_Human | 0.83170012 |
103 | SOX2_21211035_ChIP-Seq_LN229_Human | 0.83129763 |
104 | * PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.82604999 |
105 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.82078676 |
106 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 0.81734734 |
107 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.81210779 |
108 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.81086809 |
109 | SMC4_20622854_ChIP-Seq_HELA_Human | 0.80767226 |
110 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.78642695 |
111 | FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 0.77782868 |
112 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.77515296 |
113 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.77155726 |
114 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.76606128 |
115 | RARA_24833708_ChIP-Seq_LIVER_Mouse | 0.76394697 |
116 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.75891933 |
117 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.75891933 |
118 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 0.75548078 |
119 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.74985369 |
120 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.74985369 |
121 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.74379862 |
122 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.73719524 |
123 | * TP63_22573176_ChIP-Seq_HFKS_Human | 0.73668794 |
124 | P300_27268052_Chip-Seq_Bcells_Human | 0.73333341 |
125 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.72636690 |
126 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.72593491 |
127 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.72559692 |
128 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.71215962 |
129 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.69533752 |
130 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.69468601 |
131 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 0.69441628 |
132 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 0.69431204 |
133 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.69263918 |
134 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.69230543 |
135 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 0.67856188 |
136 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.65791233 |
137 | * KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.65174241 |
138 | CJUN_26792858_Chip-Seq_BT549_Human | 0.64750536 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008004_abnormal_stomach_pH | 9.60895253 |
2 | MP0005360_urolithiasis | 6.52838099 |
3 | MP0002139_abnormal_hepatobiliary_system | 5.09855686 |
4 | MP0001666_abnormal_nutrient_absorption | 4.29354460 |
5 | MP0008875_abnormal_xenobiotic_pharmacok | 4.05349798 |
6 | MP0005085_abnormal_gallbladder_physiolo | 4.05322014 |
7 | MP0003806_abnormal_nucleotide_metabolis | 3.85457248 |
8 | MP0001873_stomach_inflammation | 3.66965407 |
9 | MP0005365_abnormal_bile_salt | 3.50905554 |
10 | MP0001664_abnormal_digestion | 3.24139616 |
11 | MP0010234_abnormal_vibrissa_follicle | 3.12890029 |
12 | MP0009840_abnormal_foam_cell | 3.01560737 |
13 | MP0010329_abnormal_lipoprotein_level | 2.72073425 |
14 | MP0003252_abnormal_bile_duct | 2.70120269 |
15 | MP0002876_abnormal_thyroid_physiology | 2.34861189 |
16 | MP0000470_abnormal_stomach_morphology | 2.20324814 |
17 | MP0004264_abnormal_extraembryonic_tissu | 2.19974279 |
18 | MP0002132_abnormal_respiratory_system | 2.07157972 |
19 | MP0004019_abnormal_vitamin_homeostasis | 1.88622205 |
20 | MP0001663_abnormal_digestive_system | 1.83562771 |
21 | MP0000462_abnormal_digestive_system | 1.72798015 |
22 | MP0005083_abnormal_biliary_tract | 1.71707993 |
23 | MP0005381_digestive/alimentary_phenotyp | 1.64599821 |
24 | MP0003705_abnormal_hypodermis_morpholog | 1.57770387 |
25 | MP0003191_abnormal_cellular_cholesterol | 1.52253177 |
26 | MP0005332_abnormal_amino_acid | 1.39849077 |
27 | MP0000609_abnormal_liver_physiology | 1.38202371 |
28 | MP0002118_abnormal_lipid_homeostasis | 1.37336222 |
29 | MP0000477_abnormal_intestine_morphology | 1.34969974 |
30 | MP0005408_hypopigmentation | 1.32157828 |
31 | MP0003868_abnormal_feces_composition | 1.26911447 |
32 | MP0002796_impaired_skin_barrier | 1.23338285 |
33 | MP0006054_spinal_hemorrhage | 1.20096505 |
34 | MP0001765_abnormal_ion_homeostasis | 1.16656567 |
35 | MP0009384_cardiac_valve_regurgitation | 1.14924742 |
36 | MP0000537_abnormal_urethra_morphology | 1.08873810 |
37 | MP0003186_abnormal_redox_activity | 1.06845585 |
38 | MP0003866_abnormal_defecation | 1.06805614 |
39 | MP0003011_delayed_dark_adaptation | 1.05780080 |
40 | MP0005319_abnormal_enzyme/_coenzyme | 1.05571943 |
41 | MP0005165_increased_susceptibility_to | 1.01841088 |
42 | MP0000490_abnormal_crypts_of | 1.01628915 |
43 | MP0010352_gastrointestinal_tract_polyps | 0.98840464 |
44 | MP0005636_abnormal_mineral_homeostasis | 0.98315794 |
45 | MP0005409_darkened_coat_color | 0.97254865 |
46 | MP0009643_abnormal_urine_homeostasis | 0.96932345 |
47 | MP0005395_other_phenotype | 0.96544795 |
48 | MP0003879_abnormal_hair_cell | 0.93105189 |
49 | MP0010155_abnormal_intestine_physiology | 0.92809825 |
50 | MP0002653_abnormal_ependyma_morphology | 0.89966276 |
51 | MP0002277_abnormal_respiratory_mucosa | 0.89955874 |
52 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.88905087 |
53 | MP0000566_synostosis | 0.85862866 |
54 | MP0002168_other_aberrant_phenotype | 0.85656646 |
55 | MP0009053_abnormal_anal_canal | 0.84536666 |
56 | MP0009379_abnormal_foot_pigmentation | 0.83618800 |
57 | MP0005266_abnormal_metabolism | 0.82512110 |
58 | MP0004043_abnormal_pH_regulation | 0.82482938 |
59 | MP0003453_abnormal_keratinocyte_physiol | 0.82164148 |
60 | MP0001984_abnormal_olfaction | 0.79526555 |
61 | MP0001756_abnormal_urination | 0.76624567 |
62 | MP0010678_abnormal_skin_adnexa | 0.76036343 |
63 | MP0002254_reproductive_system_inflammat | 0.75527633 |
64 | MP0005670_abnormal_white_adipose | 0.74566756 |
65 | MP0003300_gastrointestinal_ulcer | 0.74197615 |
66 | MP0000598_abnormal_liver_morphology | 0.74047226 |
67 | MP0000678_abnormal_parathyroid_gland | 0.73384884 |
68 | MP0005451_abnormal_body_composition | 0.72838930 |
69 | MP0005084_abnormal_gallbladder_morpholo | 0.72694699 |
70 | MP0000639_abnormal_adrenal_gland | 0.72296082 |
71 | MP0003183_abnormal_peptide_metabolism | 0.71976427 |
72 | MP0005058_abnormal_lysosome_morphology | 0.71668346 |
73 | MP0009697_abnormal_copulation | 0.70740125 |
74 | MP0002822_catalepsy | 0.68695568 |
75 | MP0004947_skin_inflammation | 0.68448738 |
76 | MP0003656_abnormal_erythrocyte_physiolo | 0.65440126 |
77 | MP0000467_abnormal_esophagus_morphology | 0.65338657 |
78 | MP0004883_abnormal_blood_vessel | 0.64629093 |
79 | MP0009763_increased_sensitivity_to | 0.63857675 |
80 | MP0004133_heterotaxia | 0.63771473 |
81 | MP0005501_abnormal_skin_physiology | 0.63619494 |
82 | MP0005248_abnormal_Harderian_gland | 0.62032689 |
83 | MP0009642_abnormal_blood_homeostasis | 0.61227842 |
84 | MP0002138_abnormal_hepatobiliary_system | 0.61214913 |
85 | MP0005448_abnormal_energy_balance | 0.60855739 |
86 | MP0000538_abnormal_urinary_bladder | 0.58847844 |
87 | MP0008873_increased_physiological_sensi | 0.58835173 |
88 | MP0010368_abnormal_lymphatic_system | 0.58650309 |
89 | MP0005164_abnormal_response_to | 0.58510221 |
90 | MP0009780_abnormal_chondrocyte_physiolo | 0.58409533 |
91 | MP0005535_abnormal_body_temperature | 0.58364265 |
92 | MP0001216_abnormal_epidermal_layer | 0.57905566 |
93 | MP0000372_irregular_coat_pigmentation | 0.57568063 |
94 | MP0003718_maternal_effect | 0.56141317 |
95 | MP0001986_abnormal_taste_sensitivity | 0.55141432 |
96 | MP0005376_homeostasis/metabolism_phenot | 0.54960240 |
97 | MP0002078_abnormal_glucose_homeostasis | 0.54943475 |
98 | MP0002971_abnormal_brown_adipose | 0.53854699 |
99 | MP0003566_abnormal_cell_adhesion | 0.53090659 |
100 | MP0004147_increased_porphyrin_level | 0.52167859 |
101 | MP0002098_abnormal_vibrissa_morphology | 0.51863815 |
102 | MP0001764_abnormal_homeostasis | 0.51693937 |
103 | MP0005464_abnormal_platelet_physiology | 0.50042465 |
104 | MP0001661_extended_life_span | 0.49805885 |
105 | MP0000249_abnormal_blood_vessel | 0.49224533 |
106 | MP0005166_decreased_susceptibility_to | 0.48527099 |
107 | MP0003878_abnormal_ear_physiology | 0.48246250 |
108 | MP0005377_hearing/vestibular/ear_phenot | 0.48246250 |
109 | MP0006036_abnormal_mitochondrial_physio | 0.46284027 |
110 | MP0003950_abnormal_plasma_membrane | 0.45863176 |
111 | MP0003283_abnormal_digestive_organ | 0.45845597 |
112 | MP0000604_amyloidosis | 0.45636346 |
113 | MP0002136_abnormal_kidney_physiology | 0.44947925 |
114 | MP0005220_abnormal_exocrine_pancreas | 0.44895770 |
115 | MP0006082_CNS_inflammation | 0.44186607 |
116 | MP0003195_calcinosis | 0.43614447 |
117 | MP0002909_abnormal_adrenal_gland | 0.43512755 |
118 | MP0004782_abnormal_surfactant_physiolog | 0.43096555 |
119 | MP0001849_ear_inflammation | 0.42364247 |
120 | MP0003075_altered_response_to | 0.42266633 |
121 | MP0003953_abnormal_hormone_level | 0.42193101 |
122 | MP0000371_diluted_coat_color | 0.41835562 |
123 | MP0000377_abnormal_hair_follicle | 0.41558137 |
124 | MP0008469_abnormal_protein_level | 0.41339451 |
125 | MP0002877_abnormal_melanocyte_morpholog | 0.40969070 |
126 | MP0001845_abnormal_inflammatory_respons | 0.40867978 |
127 | MP0004185_abnormal_adipocyte_glucose | 0.40391030 |
128 | MP0005023_abnormal_wound_healing | 0.40165506 |
129 | MP0002060_abnormal_skin_morphology | 0.39823015 |
130 | MP0005334_abnormal_fat_pad | 0.39804068 |
131 | MP0008872_abnormal_physiological_respon | 0.39535538 |
132 | MP0002160_abnormal_reproductive_system | 0.38824369 |
133 | MP0002249_abnormal_larynx_morphology | 0.38606409 |
134 | MP0003119_abnormal_digestive_system | 0.37856918 |
135 | MP0009765_abnormal_xenobiotic_induced | 0.37598200 |
136 | MP0001243_abnormal_dermal_layer | 0.37472571 |
137 | MP0003638_abnormal_response/metabolism_ | 0.37036590 |
138 | MP0002282_abnormal_trachea_morphology | 0.33968714 |
139 | MP0009764_decreased_sensitivity_to | 0.33568570 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 7.98129908 |
2 | Abnormal respiratory motile cilium morphology (HP:0005938) | 7.05929946 |
3 | Abnormal respiratory epithelium morphology (HP:0012253) | 7.05929946 |
4 | Abnormal respiratory motile cilium physiology (HP:0012261) | 6.92246915 |
5 | Hypobetalipoproteinemia (HP:0003563) | 6.79173640 |
6 | Rhinitis (HP:0012384) | 6.71785040 |
7 | Abnormal ciliary motility (HP:0012262) | 6.71369650 |
8 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 6.69774663 |
9 | Absent/shortened dynein arms (HP:0200106) | 6.69774663 |
10 | Right ventricular cardiomyopathy (HP:0011663) | 6.08299779 |
11 | Intrahepatic cholestasis (HP:0001406) | 5.51226062 |
12 | Malnutrition (HP:0004395) | 5.38434151 |
13 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 5.31849530 |
14 | Chronic bronchitis (HP:0004469) | 5.03039738 |
15 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 4.90320904 |
16 | Abnormal gallbladder physiology (HP:0012438) | 4.82058278 |
17 | Cholecystitis (HP:0001082) | 4.82058278 |
18 | Xanthomatosis (HP:0000991) | 4.79790398 |
19 | Acanthocytosis (HP:0001927) | 4.78257758 |
20 | Bronchiectasis (HP:0002110) | 4.77155543 |
21 | Conjugated hyperbilirubinemia (HP:0002908) | 4.74621347 |
22 | Ileus (HP:0002595) | 4.69503757 |
23 | Hypolipoproteinemia (HP:0010981) | 4.53782218 |
24 | Nasal polyposis (HP:0100582) | 4.37868502 |
25 | Fat malabsorption (HP:0002630) | 4.27051517 |
26 | Deep venous thrombosis (HP:0002625) | 4.10493296 |
27 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 3.89342048 |
28 | Systemic lupus erythematosus (HP:0002725) | 3.75460021 |
29 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 3.69093992 |
30 | Abnormality of the nasal mucosa (HP:0000433) | 3.64391158 |
31 | Epidermoid cyst (HP:0200040) | 3.61572077 |
32 | Abnormality of purine metabolism (HP:0004352) | 3.59238291 |
33 | Male infertility (HP:0003251) | 3.56719715 |
34 | Hyperammonemia (HP:0001987) | 3.49232818 |
35 | Abnormality of vitamin metabolism (HP:0100508) | 3.30536189 |
36 | Hypercholesterolemia (HP:0003124) | 3.29561847 |
37 | Hyperglycinuria (HP:0003108) | 3.20371937 |
38 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 3.19942130 |
39 | Infertility (HP:0000789) | 3.15341508 |
40 | Spontaneous abortion (HP:0005268) | 3.11859405 |
41 | Glomerulonephritis (HP:0000099) | 3.08019050 |
42 | Joint hemorrhage (HP:0005261) | 3.06031183 |
43 | Hyperactive renin-angiotensin system (HP:0000841) | 3.05383727 |
44 | Hyperbilirubinemia (HP:0002904) | 3.02179039 |
45 | Megaloblastic anemia (HP:0001889) | 3.00515335 |
46 | Prolonged partial thromboplastin time (HP:0003645) | 2.99221869 |
47 | Abnormality of nucleobase metabolism (HP:0010932) | 2.96624451 |
48 | Recurrent sinusitis (HP:0011108) | 2.95988400 |
49 | Pigmentary retinal degeneration (HP:0001146) | 2.95472634 |
50 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.92864636 |
51 | Glycosuria (HP:0003076) | 2.88615595 |
52 | Abnormality of urine glucose concentration (HP:0011016) | 2.88615595 |
53 | Abdominal distention (HP:0003270) | 2.86162611 |
54 | Hypoglycemic coma (HP:0001325) | 2.85321063 |
55 | Increased purine levels (HP:0004368) | 2.84411804 |
56 | Hyperuricemia (HP:0002149) | 2.84411804 |
57 | Abnormality of vitamin B metabolism (HP:0004340) | 2.82333058 |
58 | Esophageal varix (HP:0002040) | 2.82331010 |
59 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.82037476 |
60 | Palpitations (HP:0001962) | 2.80423408 |
61 | Hypoalphalipoproteinemia (HP:0003233) | 2.79883397 |
62 | Bronchitis (HP:0012387) | 2.76160660 |
63 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.75936834 |
64 | Abnormality of glycine metabolism (HP:0010895) | 2.75936834 |
65 | Hydroxyprolinuria (HP:0003080) | 2.73232202 |
66 | Abnormality of proline metabolism (HP:0010907) | 2.73232202 |
67 | Proximal tubulopathy (HP:0000114) | 2.72199120 |
68 | Hyperlipoproteinemia (HP:0010980) | 2.70831829 |
69 | Abnormality of pyrimidine metabolism (HP:0004353) | 2.70069093 |
70 | Poikilocytosis (HP:0004447) | 2.65122986 |
71 | Gout (HP:0001997) | 2.63701849 |
72 | Complement deficiency (HP:0004431) | 2.56820932 |
73 | Late onset (HP:0003584) | 2.54749547 |
74 | Abnormal cartilage morphology (HP:0002763) | 2.54718160 |
75 | Recurrent otitis media (HP:0000403) | 2.54698496 |
76 | Metabolic acidosis (HP:0001942) | 2.54572847 |
77 | Cholelithiasis (HP:0001081) | 2.52747510 |
78 | Abnormal gallbladder morphology (HP:0012437) | 2.51344583 |
79 | Micronodular cirrhosis (HP:0001413) | 2.50378146 |
80 | Abnormality of the common coagulation pathway (HP:0010990) | 2.49658482 |
81 | Abnormal number of erythroid precursors (HP:0012131) | 2.49323687 |
82 | Rickets (HP:0002748) | 2.48992013 |
83 | Cupped ribs (HP:0000887) | 2.46427602 |
84 | Chronic sinusitis (HP:0011109) | 2.45750696 |
85 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 2.41960791 |
86 | Alkalosis (HP:0001948) | 2.38818165 |
87 | Ketosis (HP:0001946) | 2.36655607 |
88 | Hyperglycinemia (HP:0002154) | 2.35519963 |
89 | Skin nodule (HP:0200036) | 2.34582253 |
90 | Nausea (HP:0002018) | 2.34445257 |
91 | Decreased circulating renin level (HP:0003351) | 2.33972447 |
92 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.32266213 |
93 | Woolly hair (HP:0002224) | 2.30283424 |
94 | Abnormality of fatty-acid metabolism (HP:0004359) | 2.29928516 |
95 | Vascular calcification (HP:0004934) | 2.29688561 |
96 | Renal salt wasting (HP:0000127) | 2.29631515 |
97 | Nephritis (HP:0000123) | 2.28934253 |
98 | Lethargy (HP:0001254) | 2.28589955 |
99 | Ketoacidosis (HP:0001993) | 2.22739343 |
100 | Hyperphosphaturia (HP:0003109) | 2.21621801 |
101 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.20191158 |
102 | Autoimmune thrombocytopenia (HP:0001973) | 2.19221962 |
103 | Syncope (HP:0001279) | 2.18567812 |
104 | Gingival bleeding (HP:0000225) | 2.17809968 |
105 | Hemorrhage of the eye (HP:0011885) | 2.16832024 |
106 | Abnormality of the intrinsic pathway (HP:0010989) | 2.14032851 |
107 | Polycythemia (HP:0001901) | 2.13511576 |
108 | Sensorimotor neuropathy (HP:0007141) | 2.12126831 |
109 | Chronic hepatic failure (HP:0100626) | 2.11280049 |
110 | Reticulocytosis (HP:0001923) | 2.10845216 |
111 | Osteomalacia (HP:0002749) | 2.10158167 |
112 | Hepatocellular carcinoma (HP:0001402) | 2.09008755 |
113 | Amyloidosis (HP:0011034) | 2.08360712 |
114 | Focal segmental glomerulosclerosis (HP:0000097) | 2.07991991 |
115 | Flat acetabular roof (HP:0003180) | 2.05288070 |
116 | Abnormality of the gallbladder (HP:0005264) | 2.04810681 |
117 | Glomerulosclerosis (HP:0000096) | 2.03478654 |
118 | Gastrointestinal dysmotility (HP:0002579) | 2.03304253 |
119 | Cardiovascular calcification (HP:0011915) | 2.02994364 |
120 | Increased mean platelet volume (HP:0011877) | 2.00133697 |
121 | Mitral stenosis (HP:0001718) | 1.98996842 |
122 | Abnormality of complement system (HP:0005339) | 1.98861629 |
123 | Abnormal biliary tract morphology (HP:0012440) | 1.98248843 |
124 | Steatorrhea (HP:0002570) | 1.98001575 |
125 | Hyperaldosteronism (HP:0000859) | 1.96185643 |
126 | Occipital encephalocele (HP:0002085) | 1.95315837 |
127 | Abnormality of the gastric mucosa (HP:0004295) | 1.94156906 |
128 | Goiter (HP:0000853) | 1.93924181 |
129 | Abnormal tarsal ossification (HP:0008369) | 1.92105945 |
130 | Chronic otitis media (HP:0000389) | 1.90509030 |
131 | Male pseudohermaphroditism (HP:0000037) | 1.88252305 |
132 | Abnormal urine phosphate concentration (HP:0012599) | 1.87718372 |
133 | Generalized aminoaciduria (HP:0002909) | 1.85105256 |
134 | Widely patent fontanelles and sutures (HP:0004492) | 1.83998235 |
135 | Dicarboxylic aciduria (HP:0003215) | 1.83177544 |
136 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.83177544 |
137 | Pancreatitis (HP:0001733) | 1.81601826 |
138 | Abnormality of methionine metabolism (HP:0010901) | 1.81054215 |
139 | Spastic diplegia (HP:0001264) | 1.80648794 |
140 | Dehydration (HP:0001944) | 1.78343218 |
141 | Mesangial abnormality (HP:0001966) | 1.76509873 |
142 | Ventricular fibrillation (HP:0001663) | 1.76426983 |
143 | Abnormality of renin-angiotensin system (HP:0000847) | 1.73072061 |
144 | Hypotension (HP:0002615) | 1.71533891 |
145 | Bifid scrotum (HP:0000048) | 1.69061647 |
146 | Atelectasis (HP:0100750) | 1.63270268 |
147 | Hypophosphatemic rickets (HP:0004912) | 1.62635444 |
148 | Delayed CNS myelination (HP:0002188) | 1.60705326 |
149 | Purpura (HP:0000979) | 1.60086229 |
150 | Retinal atrophy (HP:0001105) | 1.58987607 |
151 | Hypophosphatemia (HP:0002148) | 1.55279577 |
152 | Joint swelling (HP:0001386) | 1.54479135 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ERBB4 | 7.36467057 |
2 | MAPK15 | 6.95992000 |
3 | MST1R | 6.58931637 |
4 | ACVR1B | 4.25582064 |
5 | MST4 | 3.97477676 |
6 | FRK | 3.81389657 |
7 | LMTK2 | 3.32738046 |
8 | EPHA2 | 2.74417491 |
9 | MET | 2.60858749 |
10 | MAP3K12 | 2.42632532 |
11 | PRKG2 | 2.34592601 |
12 | PKN2 | 2.11605055 |
13 | ERN1 | 2.04515087 |
14 | MAP2K2 | 1.99185548 |
15 | PTK6 | 1.84372950 |
16 | TRIB3 | 1.80818014 |
17 | MAP3K2 | 1.80269992 |
18 | MAPKAPK3 | 1.78121342 |
19 | LATS1 | 1.74254362 |
20 | RIPK1 | 1.74079093 |
21 | NUAK1 | 1.57268994 |
22 | GRK6 | 1.51781162 |
23 | STK24 | 1.46945645 |
24 | BMX | 1.40315403 |
25 | MAP3K3 | 1.30884957 |
26 | NME1 | 1.30035460 |
27 | EPHB2 | 1.27187698 |
28 | KSR2 | 1.27127963 |
29 | LRRK2 | 1.22725009 |
30 | OXSR1 | 1.20864817 |
31 | MAP2K1 | 1.17661594 |
32 | EPHA3 | 1.16664557 |
33 | TYK2 | 1.15134679 |
34 | BCKDK | 1.14858333 |
35 | TESK1 | 1.14523110 |
36 | MAP3K10 | 1.13861498 |
37 | FER | 1.11704402 |
38 | STK10 | 1.05037664 |
39 | FGFR3 | 1.04575363 |
40 | SMG1 | 1.03309944 |
41 | NEK6 | 0.99390661 |
42 | MAP3K11 | 0.98499677 |
43 | PTK2 | 0.97462324 |
44 | GRK1 | 0.96518573 |
45 | TAOK3 | 0.95859788 |
46 | NLK | 0.92506416 |
47 | PRKCI | 0.88809673 |
48 | MAP3K8 | 0.88721430 |
49 | AKT3 | 0.88168771 |
50 | DDR2 | 0.87051946 |
51 | MAP2K6 | 0.86988506 |
52 | PIM2 | 0.86767544 |
53 | ERBB2 | 0.83108157 |
54 | MAP3K9 | 0.82146099 |
55 | MYLK | 0.81903956 |
56 | NEK1 | 0.81662949 |
57 | EPHA4 | 0.81168970 |
58 | TAOK1 | 0.79719116 |
59 | MAPK11 | 0.78371868 |
60 | PAK3 | 0.72922625 |
61 | RPS6KB2 | 0.72569139 |
62 | PRKAA2 | 0.70501398 |
63 | NEK9 | 0.69151238 |
64 | FGFR4 | 0.67667139 |
65 | MAP3K1 | 0.66587270 |
66 | PRKCA | 0.66583337 |
67 | PDK3 | 0.63801531 |
68 | PDK4 | 0.63801531 |
69 | PRKCZ | 0.63373834 |
70 | EPHB1 | 0.62731414 |
71 | BCR | 0.62448078 |
72 | MAP3K7 | 0.62245054 |
73 | PIK3CG | 0.61910719 |
74 | PAK4 | 0.61519522 |
75 | STK16 | 0.61516109 |
76 | PBK | 0.61309136 |
77 | EEF2K | 0.60559414 |
78 | STK39 | 0.56571930 |
79 | STK38 | 0.56086604 |
80 | PRKACA | 0.56068436 |
81 | ARAF | 0.56026807 |
82 | WNK4 | 0.55999541 |
83 | TESK2 | 0.55938221 |
84 | PTK2B | 0.53985385 |
85 | STK3 | 0.51467850 |
86 | TBK1 | 0.50921037 |
87 | PRKCD | 0.49411517 |
88 | IRAK3 | 0.48723810 |
89 | GSK3A | 0.47504680 |
90 | CAMK2G | 0.45958858 |
91 | CDK6 | 0.45819581 |
92 | ICK | 0.43636367 |
93 | IGF1R | 0.43432805 |
94 | PDPK1 | 0.43321904 |
95 | SGK1 | 0.42037587 |
96 | WNK3 | 0.41747019 |
97 | PRKG1 | 0.41058891 |
98 | PDK2 | 0.39227566 |
99 | TRPM7 | 0.38274573 |
100 | ERBB3 | 0.38241497 |
101 | SCYL2 | 0.38191168 |
102 | DYRK1B | 0.37340501 |
103 | MATK | 0.37156859 |
104 | JAK1 | 0.36731544 |
105 | NME2 | 0.36352846 |
106 | PDGFRA | 0.36032984 |
107 | SIK1 | 0.36021754 |
108 | ABL2 | 0.34358180 |
109 | PRPF4B | 0.34160630 |
110 | CDC42BPA | 0.33225198 |
111 | PRKAA1 | 0.32592490 |
112 | PRKCE | 0.32503415 |
113 | FYN | 0.31804266 |
114 | MAP3K5 | 0.30570461 |
115 | LIMK1 | 0.30263648 |
116 | SRC | 0.30145998 |
117 | PAK2 | 0.30105567 |
118 | CSK | 0.29644499 |
119 | CAMK2B | 0.28931622 |
120 | TAOK2 | 0.28800962 |
121 | STK38L | 0.28311684 |
122 | PRKCB | 0.27918765 |
123 | TTK | 0.27732439 |
124 | PIK3CA | 0.27153364 |
125 | BMPR2 | 0.25739547 |
126 | CASK | 0.25691398 |
127 | CSNK1A1 | 0.24712465 |
128 | FLT3 | 0.24711393 |
129 | RIPK4 | 0.24438589 |
130 | PDGFRB | 0.23168522 |
131 | INSRR | 0.21913881 |
132 | RET | 0.21089015 |
133 | ROCK1 | 0.20451607 |
134 | CAMK2D | 0.20366059 |
135 | PDK1 | 0.19858942 |
136 | AKT2 | 0.19201285 |
137 | EGFR | 0.18861832 |
138 | PRKACG | 0.18772100 |
139 | MAP2K4 | 0.18447486 |
140 | PRKCQ | 0.18342256 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Fat digestion and absorption_Homo sapiens_hsa04975 | 3.88087475 |
2 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 3.45943932 |
3 | Nitrogen metabolism_Homo sapiens_hsa00910 | 3.21085169 |
4 | * Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 3.15445362 |
5 | * Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 3.00325320 |
6 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.92148361 |
7 | * Chemical carcinogenesis_Homo sapiens_hsa05204 | 2.54646144 |
8 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 2.52623497 |
9 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 2.39751935 |
10 | Arginine biosynthesis_Homo sapiens_hsa00220 | 2.31668728 |
11 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.30417093 |
12 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 2.18831632 |
13 | * Glutathione metabolism_Homo sapiens_hsa00480 | 2.12103239 |
14 | Mineral absorption_Homo sapiens_hsa04978 | 2.08184376 |
15 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 2.06879972 |
16 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.94840248 |
17 | Retinol metabolism_Homo sapiens_hsa00830 | 1.91642610 |
18 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.88934612 |
19 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.86614807 |
20 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.84932165 |
21 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.79418491 |
22 | Histidine metabolism_Homo sapiens_hsa00340 | 1.77582648 |
23 | Bile secretion_Homo sapiens_hsa04976 | 1.76978643 |
24 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.72879692 |
25 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.69331127 |
26 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.65731020 |
27 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.64310848 |
28 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.54968200 |
29 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.51287030 |
30 | Galactose metabolism_Homo sapiens_hsa00052 | 1.47179213 |
31 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.41781056 |
32 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.40984549 |
33 | Carbon metabolism_Homo sapiens_hsa01200 | 1.40882882 |
34 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.40142079 |
35 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.30490371 |
36 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.26308041 |
37 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.26295432 |
38 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.22590763 |
39 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.21750545 |
40 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.18686877 |
41 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.18558137 |
42 | Renin-angiotensin system_Homo sapiens_hsa04614 | 1.14904369 |
43 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.14564501 |
44 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.13955742 |
45 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.13875200 |
46 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.10175623 |
47 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.09828515 |
48 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.08152613 |
49 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.06370574 |
50 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.04912591 |
51 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.01540904 |
52 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.99344697 |
53 | Peroxisome_Homo sapiens_hsa04146 | 0.98119790 |
54 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.96049579 |
55 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.95682883 |
56 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.95259626 |
57 | ABC transporters_Homo sapiens_hsa02010 | 0.94959345 |
58 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.93587337 |
59 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.87410512 |
60 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.86362585 |
61 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.84781865 |
62 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.82732534 |
63 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.82346239 |
64 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.81173425 |
65 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.80526710 |
66 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.70472336 |
67 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.65176497 |
68 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.63694598 |
69 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.60744072 |
70 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.58456452 |
71 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.57827389 |
72 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.56220425 |
73 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.55760063 |
74 | Sulfur relay system_Homo sapiens_hsa04122 | 0.52881593 |
75 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.45428532 |
76 | Metabolic pathways_Homo sapiens_hsa01100 | 0.39944303 |
77 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.39747166 |
78 | Tight junction_Homo sapiens_hsa04530 | 0.38582837 |
79 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.37639812 |
80 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.36129134 |
81 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.34768762 |
82 | Other glycan degradation_Homo sapiens_hsa00511 | 0.34490503 |
83 | Prion diseases_Homo sapiens_hsa05020 | 0.31687830 |
84 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.30384457 |
85 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.29860727 |
86 | Lysine degradation_Homo sapiens_hsa00310 | 0.29109615 |
87 | Thyroid cancer_Homo sapiens_hsa05216 | 0.25599866 |
88 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.25523362 |
89 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.25382805 |
90 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.24327091 |
91 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.18507517 |
92 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.17571205 |
93 | Bladder cancer_Homo sapiens_hsa05219 | 0.17497821 |
94 | Adherens junction_Homo sapiens_hsa04520 | 0.11491934 |
95 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.08580679 |
96 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.07952364 |
97 | Hepatitis C_Homo sapiens_hsa05160 | 0.07341415 |
98 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.05967698 |
99 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.05829053 |
100 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.03603221 |
101 | Insulin resistance_Homo sapiens_hsa04931 | 0.03356870 |
102 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.03135947 |
103 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.01406939 |
104 | Pertussis_Homo sapiens_hsa05133 | 0.01038313 |
105 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.00380004 |
106 | Cocaine addiction_Homo sapiens_hsa05030 | -0.0730960 |
107 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | -0.0693853 |
108 | African trypanosomiasis_Homo sapiens_hsa05143 | -0.0466627 |
109 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | -0.0292919 |
110 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | -0.0114260 |
111 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | -0.0084703 |
112 | Huntingtons disease_Homo sapiens_hsa05016 | -0.0019929 |