

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | protein neddylation (GO:0045116) | 9.41215091 |
| 2 | thrombin receptor signaling pathway (GO:0070493) | 7.87901074 |
| 3 | neutrophil activation involved in immune response (GO:0002283) | 7.12396640 |
| 4 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 7.07072836 |
| 5 | blood coagulation, intrinsic pathway (GO:0007597) | 6.11472700 |
| 6 | regulation of platelet aggregation (GO:0090330) | 5.93966099 |
| 7 | regulation of platelet activation (GO:0010543) | 5.92106229 |
| 8 | adenosine receptor signaling pathway (GO:0001973) | 5.85740147 |
| 9 | negative regulation of norepinephrine secretion (GO:0010700) | 5.63624362 |
| 10 | leukocyte migration involved in inflammatory response (GO:0002523) | 5.63539153 |
| 11 | low-density lipoprotein particle remodeling (GO:0034374) | 5.53677121 |
| 12 | regulation of integrin-mediated signaling pathway (GO:2001044) | 5.45124894 |
| 13 | negative regulation of heart rate (GO:0010459) | 5.34933779 |
| 14 | negative regulation of thymocyte apoptotic process (GO:0070244) | 5.28516552 |
| 15 | platelet aggregation (GO:0070527) | 5.27620967 |
| 16 | negative regulation of platelet activation (GO:0010544) | 5.26593354 |
| 17 | negative regulation of homotypic cell-cell adhesion (GO:0034111) | 5.12422612 |
| 18 | negative regulation of macrophage derived foam cell differentiation (GO:0010745) | 5.00045921 |
| 19 | lipoxygenase pathway (GO:0019372) | 4.87879706 |
| 20 | beta-amyloid metabolic process (GO:0050435) | 4.71324105 |
| 21 | positive regulation of endothelial cell differentiation (GO:0045603) | 4.54213227 |
| 22 | fusion of sperm to egg plasma membrane (GO:0007342) | 4.46023272 |
| 23 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 4.42943214 |
| 24 | high-density lipoprotein particle remodeling (GO:0034375) | 4.38932543 |
| 25 | platelet degranulation (GO:0002576) | 4.30314654 |
| 26 | negative regulation of response to food (GO:0032096) | 4.27350768 |
| 27 | negative regulation of appetite (GO:0032099) | 4.27350768 |
| 28 | purinergic nucleotide receptor signaling pathway (GO:0035590) | 4.19827908 |
| 29 | negative regulation of protein localization to cell surface (GO:2000009) | 4.17589923 |
| 30 | regulation of Golgi to plasma membrane protein transport (GO:0042996) | 4.17544823 |
| 31 | positive regulation of mast cell activation (GO:0033005) | 4.10476552 |
| 32 | neutrophil activation (GO:0042119) | 4.08842508 |
| 33 | reverse cholesterol transport (GO:0043691) | 4.07381442 |
| 34 | regulation of norepinephrine secretion (GO:0014061) | 4.04207401 |
| 35 | angiogenesis involved in wound healing (GO:0060055) | 4.01921338 |
| 36 | positive regulation of cAMP-mediated signaling (GO:0043950) | 3.98065730 |
| 37 | regulation of integrin activation (GO:0033623) | 3.97540993 |
| 38 | phospholipid homeostasis (GO:0055091) | 3.95797132 |
| 39 | regulation of lipoprotein metabolic process (GO:0050746) | 3.94773177 |
| 40 | positive regulation of systemic arterial blood pressure (GO:0003084) | 3.90547521 |
| 41 | polyamine biosynthetic process (GO:0006596) | 3.85613593 |
| 42 | positive regulation of Rho protein signal transduction (GO:0035025) | 3.82921527 |
| 43 | platelet formation (GO:0030220) | 3.82414885 |
| 44 | positive regulation of mitochondrial calcium ion concentration (GO:0051561) | 3.79387338 |
| 45 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 3.78705653 |
| 46 | regulation of macrophage derived foam cell differentiation (GO:0010743) | 3.78612742 |
| 47 | extracellular fibril organization (GO:0043206) | 3.78600021 |
| 48 | positive regulation of macrophage differentiation (GO:0045651) | 3.78078424 |
| 49 | platelet activation (GO:0030168) | 3.74183504 |
| 50 | negative regulation of heart contraction (GO:0045822) | 3.71254560 |
| 51 | long-chain fatty acid biosynthetic process (GO:0042759) | 3.65161133 |
| 52 | purinergic receptor signaling pathway (GO:0035587) | 3.62196351 |
| 53 | positive regulation of receptor recycling (GO:0001921) | 3.61156188 |
| 54 | negative regulation of catecholamine secretion (GO:0033604) | 3.60585408 |
| 55 | regulation of cholesterol efflux (GO:0010874) | 3.60109302 |
| 56 | megakaryocyte development (GO:0035855) | 3.58007756 |
| 57 | homotypic cell-cell adhesion (GO:0034109) | 3.57817641 |
| 58 | regulation of homotypic cell-cell adhesion (GO:0034110) | 3.56466357 |
| 59 | granulocyte activation (GO:0036230) | 3.55604958 |
| 60 | positive regulation of blood coagulation (GO:0030194) | 3.51924501 |
| 61 | positive regulation of hemostasis (GO:1900048) | 3.51924501 |
| 62 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 3.50974042 |
| 63 | L-phenylalanine catabolic process (GO:0006559) | 3.50974042 |
| 64 | G-protein coupled purinergic receptor signaling pathway (GO:0035588) | 3.47827639 |
| 65 | negative regulation of neural precursor cell proliferation (GO:2000178) | 3.44829416 |
| 66 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 3.43548085 |
| 67 | regulation of female receptivity (GO:0045924) | 3.30840274 |
| 68 | termination of G-protein coupled receptor signaling pathway (GO:0038032) | 3.26721815 |
| 69 | negative regulation of T cell apoptotic process (GO:0070233) | 3.26659127 |
| 70 | plasma membrane fusion (GO:0045026) | 3.25193621 |
| 71 | regulation of MHC class II biosynthetic process (GO:0045346) | 3.24149454 |
| 72 | mitochondrial calcium ion transport (GO:0006851) | 3.21273728 |
| 73 | termination of signal transduction (GO:0023021) | 3.16445552 |
| 74 | positive regulation of coagulation (GO:0050820) | 3.14169844 |
| 75 | regulation of receptor recycling (GO:0001919) | 3.11166086 |
| 76 | fibril organization (GO:0097435) | 3.10481271 |
| 77 | autophagic vacuole fusion (GO:0000046) | 3.09618030 |
| 78 | regulation of hemostasis (GO:1900046) | 3.09207800 |
| 79 | regulation of blood coagulation (GO:0030193) | 3.09207800 |
| 80 | regulation of endothelial cell differentiation (GO:0045601) | 3.06536554 |
| 81 | tyrosine metabolic process (GO:0006570) | 3.04715994 |
| 82 | vesicle targeting (GO:0006903) | 2.97141915 |
| 83 | sequestering of actin monomers (GO:0042989) | 2.95851646 |
| 84 | cellular biogenic amine biosynthetic process (GO:0042401) | 2.95439734 |
| 85 | dopamine transport (GO:0015872) | 2.95332391 |
| 86 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 2.95096514 |
| 87 | negative regulation of calcium ion transmembrane transport (GO:1903170) | 2.93722321 |
| 88 | negative regulation of calcium ion transmembrane transporter activity (GO:1901020) | 2.93722321 |
| 89 | positive regulation of protein homodimerization activity (GO:0090073) | 2.91825060 |
| 90 | L-phenylalanine metabolic process (GO:0006558) | 2.91672351 |
| 91 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 2.91672351 |
| 92 | negative regulation of blood coagulation (GO:0030195) | 2.90356800 |
| 93 | negative regulation of hemostasis (GO:1900047) | 2.90356800 |
| 94 | female mating behavior (GO:0060180) | 2.87169261 |
| 95 | monoamine transport (GO:0015844) | 2.87126715 |
| 96 | fatty acid elongation (GO:0030497) | 2.87103733 |
| 97 | leukocyte degranulation (GO:0043299) | 2.86882204 |
| 98 | negative regulation of protein localization to plasma membrane (GO:1903077) | 2.85805963 |
| 99 | relaxation of smooth muscle (GO:0044557) | 2.84631957 |
| 100 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.84043761 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 5.10349108 |
| 2 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 4.52194098 |
| 3 | SCL_19346495_ChIP-Seq_HPC-7_Human | 3.70441817 |
| 4 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.44532284 |
| 5 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 3.13521946 |
| 6 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 3.10514411 |
| 7 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 3.07123846 |
| 8 | GATA1_19941826_ChIP-Seq_K562_Human | 2.87656858 |
| 9 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 2.82843984 |
| 10 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.80291225 |
| 11 | GATA2_19941826_ChIP-Seq_K562_Human | 2.50429860 |
| 12 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.49720010 |
| 13 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.47800220 |
| 14 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 2.41815387 |
| 15 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.38723181 |
| 16 | HTT_18923047_ChIP-ChIP_STHdh_Human | 2.36820017 |
| 17 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.27411676 |
| 18 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.24548636 |
| 19 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.19948885 |
| 20 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 2.19637066 |
| 21 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 2.15310198 |
| 22 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.07160902 |
| 23 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 2.00024816 |
| 24 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 1.98963072 |
| 25 | SPI1_23127762_ChIP-Seq_K562_Human | 1.97349316 |
| 26 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.94783173 |
| 27 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.93936961 |
| 28 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.92297492 |
| 29 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.82116940 |
| 30 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.77828927 |
| 31 | GATA1_22025678_ChIP-Seq_K562_Human | 1.65123452 |
| 32 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.64874612 |
| 33 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.52740836 |
| 34 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 1.49032657 |
| 35 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.44023841 |
| 36 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.43456389 |
| 37 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.42908098 |
| 38 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.40977008 |
| 39 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.40977008 |
| 40 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.38249762 |
| 41 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.37703477 |
| 42 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.37655054 |
| 43 | VDR_22108803_ChIP-Seq_LS180_Human | 1.34222422 |
| 44 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.34175152 |
| 45 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.33783823 |
| 46 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.31169482 |
| 47 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.27525092 |
| 48 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.25590958 |
| 49 | KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse | 1.18166417 |
| 50 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.16173247 |
| 51 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.14155931 |
| 52 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.12196209 |
| 53 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.11158677 |
| 54 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.10632230 |
| 55 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.08105994 |
| 56 | ETS1_22383799_ChIP-Seq_G1ME_Mouse | 1.05885699 |
| 57 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.05129103 |
| 58 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.04482429 |
| 59 | LMO2_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.03178269 |
| 60 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.00958515 |
| 61 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.00804888 |
| 62 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.99387307 |
| 63 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.97755511 |
| 64 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.97010640 |
| 65 | OCT1_27270436_Chip-Seq_PROSTATE_Human | 0.94743585 |
| 66 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.93609333 |
| 67 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.91867425 |
| 68 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.91728565 |
| 69 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.91668189 |
| 70 | GATA4_25053715_ChIP-Seq_YYC3_Human | 0.91655083 |
| 71 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.91292555 |
| 72 | EWS_26573619_Chip-Seq_HEK293_Human | 0.91080529 |
| 73 | AR_25329375_ChIP-Seq_VCAP_Human | 0.90180898 |
| 74 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.89712750 |
| 75 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.88095934 |
| 76 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.87192549 |
| 77 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.86711065 |
| 78 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.85847323 |
| 79 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 0.84983473 |
| 80 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.82772168 |
| 81 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.82772168 |
| 82 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.82026448 |
| 83 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.80252834 |
| 84 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.80178940 |
| 85 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.79548651 |
| 86 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.78911452 |
| 87 | AR_20517297_ChIP-Seq_VCAP_Human | 0.78007727 |
| 88 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.77935639 |
| 89 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.77826644 |
| 90 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.77472902 |
| 91 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.77104453 |
| 92 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.76217206 |
| 93 | PU1_27457419_Chip-Seq_LIVER_Mouse | 0.76012244 |
| 94 | GATA3_26560356_Chip-Seq_TH2_Human | 0.74724787 |
| 95 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.74603094 |
| 96 | CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.73475492 |
| 97 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.73455660 |
| 98 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 0.73187545 |
| 99 | SOX2_22085726_ChIP-Seq_NPCs_Mouse | 0.73156715 |
| 100 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.72508660 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008004_abnormal_stomach_pH | 5.01236595 |
| 2 | MP0003724_increased_susceptibility_to | 3.53973451 |
| 3 | MP0000465_gastrointestinal_hemorrhage | 3.06604693 |
| 4 | MP0000343_altered_response_to | 2.47976343 |
| 5 | MP0000230_abnormal_systemic_arterial | 2.40831630 |
| 6 | MP0004510_myositis | 2.35595086 |
| 7 | MP0002736_abnormal_nociception_after | 2.31132900 |
| 8 | MP0003566_abnormal_cell_adhesion | 2.24583579 |
| 9 | MP0001879_abnormal_lymphatic_vessel | 2.17828613 |
| 10 | MP0005410_abnormal_fertilization | 2.15925919 |
| 11 | MP0001835_abnormal_antigen_presentation | 2.14891784 |
| 12 | MP0005083_abnormal_biliary_tract | 2.10183417 |
| 13 | MP0005084_abnormal_gallbladder_morpholo | 2.05575247 |
| 14 | MP0008872_abnormal_physiological_respon | 2.03367645 |
| 15 | MP0005464_abnormal_platelet_physiology | 10.6077637 |
| 16 | MP0003303_peritoneal_inflammation | 1.98853200 |
| 17 | MP0005167_abnormal_blood-brain_barrier | 1.96953913 |
| 18 | MP0003638_abnormal_response/metabolism_ | 1.95113276 |
| 19 | MP0003879_abnormal_hair_cell | 1.93119612 |
| 20 | MP0004084_abnormal_cardiac_muscle | 1.92584026 |
| 21 | MP0005646_abnormal_pituitary_gland | 1.84309738 |
| 22 | MP0008775_abnormal_heart_ventricle | 1.79316597 |
| 23 | MP0005058_abnormal_lysosome_morphology | 1.74110819 |
| 24 | MP0003828_pulmonary_edema | 1.65048505 |
| 25 | MP0004130_abnormal_muscle_cell | 1.60855487 |
| 26 | MP0010155_abnormal_intestine_physiology | 1.60098033 |
| 27 | MP0005671_abnormal_response_to | 1.53427717 |
| 28 | MP0010329_abnormal_lipoprotein_level | 1.52934768 |
| 29 | MP0002733_abnormal_thermal_nociception | 1.47236941 |
| 30 | MP0002148_abnormal_hypersensitivity_rea | 1.46233637 |
| 31 | MP0009780_abnormal_chondrocyte_physiolo | 1.42189654 |
| 32 | MP0001968_abnormal_touch/_nociception | 1.42017740 |
| 33 | MP0002132_abnormal_respiratory_system | 1.39715971 |
| 34 | MP0004036_abnormal_muscle_relaxation | 1.38955893 |
| 35 | MP0001851_eye_inflammation | 1.38293019 |
| 36 | MP0004215_abnormal_myocardial_fiber | 1.32927946 |
| 37 | MP0000249_abnormal_blood_vessel | 1.31661513 |
| 38 | MP0009697_abnormal_copulation | 1.30747080 |
| 39 | MP0001545_abnormal_hematopoietic_system | 1.25575246 |
| 40 | MP0005397_hematopoietic_system_phenotyp | 1.25575246 |
| 41 | MP0001663_abnormal_digestive_system | 1.25269243 |
| 42 | MP0009763_increased_sensitivity_to | 1.21951189 |
| 43 | MP0005000_abnormal_immune_tolerance | 1.21890917 |
| 44 | MP0002398_abnormal_bone_marrow | 1.18683558 |
| 45 | MP0004947_skin_inflammation | 1.17961676 |
| 46 | MP0003136_yellow_coat_color | 1.09350361 |
| 47 | MP0006276_abnormal_autonomic_nervous | 1.08679686 |
| 48 | MP0008874_decreased_physiological_sensi | 1.07872633 |
| 49 | MP0009642_abnormal_blood_homeostasis | 1.05387607 |
| 50 | MP0003656_abnormal_erythrocyte_physiolo | 1.00821733 |
| 51 | MP0003011_delayed_dark_adaptation | 0.99125674 |
| 52 | MP0001533_abnormal_skeleton_physiology | 0.98594558 |
| 53 | MP0000015_abnormal_ear_pigmentation | 0.97598858 |
| 54 | MP0001970_abnormal_pain_threshold | 0.96468049 |
| 55 | MP0001765_abnormal_ion_homeostasis | 0.93554512 |
| 56 | MP0000858_altered_metastatic_potential | 0.91871481 |
| 57 | MP0002723_abnormal_immune_serum | 0.91038454 |
| 58 | MP0003866_abnormal_defecation | 0.90892541 |
| 59 | MP0009765_abnormal_xenobiotic_induced | 0.90745352 |
| 60 | MP0002972_abnormal_cardiac_muscle | 0.88753571 |
| 61 | MP0006054_spinal_hemorrhage | 0.88571984 |
| 62 | MP0006036_abnormal_mitochondrial_physio | 0.88549491 |
| 63 | MP0009764_decreased_sensitivity_to | 0.87637141 |
| 64 | MP0005501_abnormal_skin_physiology | 0.85263276 |
| 65 | MP0002429_abnormal_blood_cell | 0.85092861 |
| 66 | MP0004134_abnormal_chest_morphology | 0.83646928 |
| 67 | MP0006138_congestive_heart_failure | 0.82844387 |
| 68 | MP0005165_increased_susceptibility_to | 0.82444091 |
| 69 | MP0005385_cardiovascular_system_phenoty | 0.81624962 |
| 70 | MP0001544_abnormal_cardiovascular_syste | 0.81624962 |
| 71 | MP0000689_abnormal_spleen_morphology | 0.81296290 |
| 72 | MP0001800_abnormal_humoral_immune | 0.80129584 |
| 73 | MP0005647_abnormal_sex_gland | 0.79782216 |
| 74 | MP0001756_abnormal_urination | 0.79559322 |
| 75 | MP0003186_abnormal_redox_activity | 0.79087435 |
| 76 | MP0005381_digestive/alimentary_phenotyp | 0.78980754 |
| 77 | MP0002452_abnormal_antigen_presenting | 0.78427165 |
| 78 | MP0002118_abnormal_lipid_homeostasis | 0.78084888 |
| 79 | MP0001664_abnormal_digestion | 0.77360699 |
| 80 | MP0005187_abnormal_penis_morphology | 0.77173225 |
| 81 | MP0005409_darkened_coat_color | 0.75720101 |
| 82 | MP0000383_abnormal_hair_follicle | 0.72933658 |
| 83 | MP0001845_abnormal_inflammatory_respons | 0.71440393 |
| 84 | MP0002735_abnormal_chemical_nociception | 0.71332669 |
| 85 | MP0005365_abnormal_bile_salt | 0.70550021 |
| 86 | MP0002722_abnormal_immune_system | 0.68940360 |
| 87 | MP0005620_abnormal_muscle_contractility | 0.68008804 |
| 88 | MP0002877_abnormal_melanocyte_morpholog | 0.67966507 |
| 89 | MP0002128_abnormal_blood_circulation | 0.67907816 |
| 90 | MP0003436_decreased_susceptibility_to | 0.67228070 |
| 91 | MP0005023_abnormal_wound_healing | 0.66513072 |
| 92 | MP0002653_abnormal_ependyma_morphology | 0.66489622 |
| 93 | MP0000358_abnormal_cell_content/ | 0.66198861 |
| 94 | MP0002998_abnormal_bone_remodeling | 0.66017194 |
| 95 | MP0004272_abnormal_basement_membrane | 0.65174774 |
| 96 | MP0005174_abnormal_tail_pigmentation | 0.65014989 |
| 97 | MP0009333_abnormal_splenocyte_physiolog | 0.64989659 |
| 98 | MP0005666_abnormal_adipose_tissue | 0.64770220 |
| 99 | MP0004085_abnormal_heartbeat | 0.64535401 |
| 100 | MP0002420_abnormal_adaptive_immunity | 0.63874736 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormal platelet volume (HP:0011876) | 9.64320885 |
| 2 | Petechiae (HP:0000967) | 9.50009473 |
| 3 | Purpura (HP:0000979) | 8.76491454 |
| 4 | Epistaxis (HP:0000421) | 7.72044429 |
| 5 | Hyperlipoproteinemia (HP:0010980) | 7.48204055 |
| 6 | Gingival bleeding (HP:0000225) | 6.59318588 |
| 7 | Abnormal platelet function (HP:0011869) | 5.40321418 |
| 8 | Impaired platelet aggregation (HP:0003540) | 5.40321418 |
| 9 | Dyschromatopsia (HP:0007641) | 4.31397738 |
| 10 | Poikilocytosis (HP:0004447) | 4.27881051 |
| 11 | Acanthocytosis (HP:0001927) | 4.18071633 |
| 12 | Abnormal pupillary function (HP:0007686) | 3.74754968 |
| 13 | Abnormality of the common coagulation pathway (HP:0010990) | 3.74189043 |
| 14 | Conjunctival telangiectasia (HP:0000524) | 3.74163605 |
| 15 | Paralysis (HP:0003470) | 3.68194870 |
| 16 | Spontaneous hematomas (HP:0007420) | 3.64982879 |
| 17 | Abnormality of lateral ventricle (HP:0030047) | 3.38047420 |
| 18 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 3.36482443 |
| 19 | Bruising susceptibility (HP:0000978) | 3.35626144 |
| 20 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 3.27019570 |
| 21 | Xanthomatosis (HP:0000991) | 3.02771056 |
| 22 | Increased density of long bones (HP:0006392) | 2.88647920 |
| 23 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 2.83178463 |
| 24 | Joint swelling (HP:0001386) | 2.77937663 |
| 25 | Abnormal auditory evoked potentials (HP:0006958) | 2.70435915 |
| 26 | Joint hemorrhage (HP:0005261) | 2.67866908 |
| 27 | Hepatosplenomegaly (HP:0001433) | 2.66131004 |
| 28 | Upper limb muscle weakness (HP:0003484) | 2.56493078 |
| 29 | Male infertility (HP:0003251) | 2.56327609 |
| 30 | Decreased central vision (HP:0007663) | 2.56241195 |
| 31 | Generalized aminoaciduria (HP:0002909) | 2.54738058 |
| 32 | Spontaneous abortion (HP:0005268) | 2.49747533 |
| 33 | Abnormal ciliary motility (HP:0012262) | 2.42638071 |
| 34 | Thyroid-stimulating hormone excess (HP:0002925) | 2.41856298 |
| 35 | Nausea (HP:0002018) | 2.39914802 |
| 36 | Papillary thyroid carcinoma (HP:0002895) | 2.38253871 |
| 37 | Increased IgM level (HP:0003496) | 2.34551626 |
| 38 | Stomatitis (HP:0010280) | 2.28585981 |
| 39 | Tinnitus (HP:0000360) | 2.27667110 |
| 40 | Ventricular fibrillation (HP:0001663) | 2.12831177 |
| 41 | Dysautonomia (HP:0002459) | 2.10464038 |
| 42 | 3-Methylglutaconic aciduria (HP:0003535) | 2.09689680 |
| 43 | Abnormality of iron homeostasis (HP:0011031) | 2.08386609 |
| 44 | Abnormality of macrophages (HP:0004311) | 2.07994159 |
| 45 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.06369120 |
| 46 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.06369120 |
| 47 | Hypophosphatemic rickets (HP:0004912) | 2.04945238 |
| 48 | Prolonged bleeding time (HP:0003010) | 11.5874806 |
| 49 | Menorrhagia (HP:0000132) | 10.9224031 |
| 50 | Increased mean platelet volume (HP:0011877) | 10.3328899 |
| 51 | Biliary tract neoplasm (HP:0100574) | 1.99061855 |
| 52 | Infertility (HP:0000789) | 1.92503816 |
| 53 | Tongue fasciculations (HP:0001308) | 1.90740227 |
| 54 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.85972982 |
| 55 | Arthropathy (HP:0003040) | 1.84335067 |
| 56 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.81209284 |
| 57 | Abnormality of alanine metabolism (HP:0010916) | 1.81209284 |
| 58 | Hyperalaninemia (HP:0003348) | 1.81209284 |
| 59 | Episodic fever (HP:0001954) | 1.79045455 |
| 60 | Absent/shortened dynein arms (HP:0200106) | 1.75628032 |
| 61 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.75628032 |
| 62 | Myocardial infarction (HP:0001658) | 1.75437789 |
| 63 | Basal ganglia calcification (HP:0002135) | 1.70879078 |
| 64 | Encephalitis (HP:0002383) | 1.69292533 |
| 65 | Hyperthyroidism (HP:0000836) | 1.69202152 |
| 66 | Muscle fibrillation (HP:0010546) | 1.68774632 |
| 67 | Abnormality of the prostate (HP:0008775) | 1.68441989 |
| 68 | Distal lower limb amyotrophy (HP:0008944) | 1.66339907 |
| 69 | Thyroid carcinoma (HP:0002890) | 1.66208069 |
| 70 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.65760633 |
| 71 | Mitral stenosis (HP:0001718) | 1.65449692 |
| 72 | Arterial thrombosis (HP:0004420) | 1.65168853 |
| 73 | Transitional cell carcinoma of the bladder (HP:0006740) | 1.63514407 |
| 74 | Leiomyosarcoma (HP:0100243) | 1.62736477 |
| 75 | Uterine leiomyosarcoma (HP:0002891) | 1.62736477 |
| 76 | Polyphagia (HP:0002591) | 1.62665168 |
| 77 | Increased serum ferritin (HP:0003281) | 1.62578906 |
| 78 | Renal Fanconi syndrome (HP:0001994) | 1.60785993 |
| 79 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 1.57628459 |
| 80 | Testicular neoplasm (HP:0010788) | 1.55926590 |
| 81 | Polycythemia (HP:0001901) | 1.52071649 |
| 82 | Vertigo (HP:0002321) | 1.50910133 |
| 83 | Back pain (HP:0003418) | 1.48332293 |
| 84 | Autoimmune hemolytic anemia (HP:0001890) | 1.46556386 |
| 85 | Abnormal spermatogenesis (HP:0008669) | 1.46285379 |
| 86 | Bladder neoplasm (HP:0009725) | 1.45450244 |
| 87 | Bladder carcinoma (HP:0002862) | 1.45450244 |
| 88 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 1.42730631 |
| 89 | Exertional dyspnea (HP:0002875) | 1.40249312 |
| 90 | Vascular calcification (HP:0004934) | 1.38650534 |
| 91 | Congenital sensorineural hearing impairment (HP:0008527) | 1.38334611 |
| 92 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 1.36766792 |
| 93 | Central scotoma (HP:0000603) | 1.36147004 |
| 94 | Neoplasm of the rectum (HP:0100743) | 1.35162294 |
| 95 | Abnormality of the Achilles tendon (HP:0005109) | 1.34214016 |
| 96 | Chronic obstructive pulmonary disease (HP:0006510) | 1.32609358 |
| 97 | Obstructive lung disease (HP:0006536) | 1.32609358 |
| 98 | Ileus (HP:0002595) | 1.30342345 |
| 99 | Lower limb amyotrophy (HP:0007210) | 1.29293969 |
| 100 | Dysostosis multiplex (HP:0000943) | 1.28758675 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MST4 | 6.30304029 |
| 2 | BMX | 4.54141600 |
| 3 | MYLK | 4.07316093 |
| 4 | RIPK4 | 4.04670354 |
| 5 | BTK | 2.98429048 |
| 6 | TEC | 2.90663455 |
| 7 | PTK2B | 2.89816427 |
| 8 | EIF2AK1 | 2.70552592 |
| 9 | GRK5 | 2.36844549 |
| 10 | ILK | 2.32241243 |
| 11 | TAOK3 | 2.20964221 |
| 12 | CSF1R | 2.16914621 |
| 13 | PIK3CG | 2.08800020 |
| 14 | SYK | 2.00381700 |
| 15 | MAPKAPK3 | 1.97818143 |
| 16 | GRK6 | 1.93429305 |
| 17 | ZAP70 | 1.87162571 |
| 18 | PLK2 | 1.74762055 |
| 19 | STK3 | 1.72534686 |
| 20 | BMPR2 | 1.62955771 |
| 21 | FGR | 1.62872850 |
| 22 | DAPK3 | 1.34449409 |
| 23 | ADRBK2 | 1.34335955 |
| 24 | LMTK2 | 1.31133599 |
| 25 | PAK1 | 1.31124366 |
| 26 | ACVR1B | 1.25261336 |
| 27 | TLK1 | 1.19572347 |
| 28 | HCK | 1.18681952 |
| 29 | TNK2 | 1.16930313 |
| 30 | PNCK | 1.14328653 |
| 31 | IKBKB | 1.12293680 |
| 32 | DAPK2 | 1.11955400 |
| 33 | PIM2 | 1.10651510 |
| 34 | TRIM28 | 1.10613985 |
| 35 | TNIK | 1.07115937 |
| 36 | LYN | 1.06152462 |
| 37 | EPHB2 | 1.03718720 |
| 38 | BLK | 0.98899620 |
| 39 | EPHA3 | 0.95595393 |
| 40 | NUAK1 | 0.88733995 |
| 41 | MATK | 0.86169128 |
| 42 | FES | 0.85479573 |
| 43 | ADRBK1 | 0.85330996 |
| 44 | ERBB2 | 0.84753972 |
| 45 | STK24 | 0.84316570 |
| 46 | MAP4K2 | 0.81740999 |
| 47 | FER | 0.81639407 |
| 48 | RET | 0.80462409 |
| 49 | DAPK1 | 0.78401608 |
| 50 | BMPR1B | 0.75890192 |
| 51 | MAP3K5 | 0.74773210 |
| 52 | ITK | 0.74426529 |
| 53 | PRKD1 | 0.72833470 |
| 54 | PKN1 | 0.72071580 |
| 55 | MINK1 | 0.68012378 |
| 56 | TXK | 0.63974325 |
| 57 | IRAK1 | 0.62903700 |
| 58 | MARK3 | 0.60629913 |
| 59 | TESK2 | 0.59942273 |
| 60 | STK16 | 0.56719839 |
| 61 | PAK3 | 0.56290494 |
| 62 | SIK3 | 0.56123052 |
| 63 | GRK1 | 0.55619620 |
| 64 | MAP3K12 | 0.55456979 |
| 65 | PRKACG | 0.55355926 |
| 66 | MAP2K3 | 0.49871234 |
| 67 | TAOK2 | 0.49729962 |
| 68 | MAPK12 | 0.49570993 |
| 69 | ZAK | 0.49569811 |
| 70 | STK4 | 0.47614683 |
| 71 | PRKG1 | 0.45520014 |
| 72 | ARAF | 0.44381774 |
| 73 | MAPK13 | 0.44041928 |
| 74 | MAP2K1 | 0.42649555 |
| 75 | CAMKK2 | 0.42351014 |
| 76 | PDK1 | 0.41571427 |
| 77 | BRSK2 | 0.39818921 |
| 78 | PDGFRB | 0.39735960 |
| 79 | ROCK1 | 0.38747474 |
| 80 | CSK | 0.38428737 |
| 81 | FYN | 0.37208636 |
| 82 | PRKCE | 0.35633064 |
| 83 | LCK | 0.32439100 |
| 84 | PRKCB | 0.32082253 |
| 85 | PDPK1 | 0.31409126 |
| 86 | PRKCA | 0.30624696 |
| 87 | CDK14 | 0.30427669 |
| 88 | CAMK2G | 0.30263606 |
| 89 | CAMK2A | 0.29620745 |
| 90 | IGF1R | 0.29338562 |
| 91 | PRKCD | 0.29018048 |
| 92 | TAOK1 | 0.26512301 |
| 93 | PRKCQ | 0.25051110 |
| 94 | SRC | 0.24456919 |
| 95 | DYRK3 | 0.22717406 |
| 96 | JAK2 | 0.22269188 |
| 97 | DYRK1A | 0.21196762 |
| 98 | PLK3 | 0.21048737 |
| 99 | CAMK2D | 0.20450167 |
| 100 | PRKCG | 0.20340937 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Platelet activation_Homo sapiens_hsa04611 | 5.69024816 |
| 2 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 3.77435261 |
| 3 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 3.36326583 |
| 4 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 2.69997137 |
| 5 | ECM-receptor interaction_Homo sapiens_hsa04512 | 2.55980144 |
| 6 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.53504284 |
| 7 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 2.50985468 |
| 8 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.18171124 |
| 9 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.00691578 |
| 10 | Gap junction_Homo sapiens_hsa04540 | 1.95441930 |
| 11 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.94793223 |
| 12 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.84935075 |
| 13 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.83052330 |
| 14 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.79991407 |
| 15 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.71944006 |
| 16 | Alcoholism_Homo sapiens_hsa05034 | 1.66271796 |
| 17 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.58887375 |
| 18 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.55936745 |
| 19 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.47245956 |
| 20 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.47120742 |
| 21 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.34254578 |
| 22 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.32348998 |
| 23 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.32130532 |
| 24 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.27693640 |
| 25 | Endocytosis_Homo sapiens_hsa04144 | 1.26451832 |
| 26 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.24426953 |
| 27 | Shigellosis_Homo sapiens_hsa05131 | 1.11258706 |
| 28 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 1.08867494 |
| 29 | Mismatch repair_Homo sapiens_hsa03430 | 1.08069669 |
| 30 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.04584876 |
| 31 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.04075016 |
| 32 | Olfactory transduction_Homo sapiens_hsa04740 | 1.03881719 |
| 33 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.00137664 |
| 34 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.98080334 |
| 35 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.97861548 |
| 36 | Circadian entrainment_Homo sapiens_hsa04713 | 0.97685152 |
| 37 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.96896929 |
| 38 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.93782545 |
| 39 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.93369732 |
| 40 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.92261601 |
| 41 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.92065008 |
| 42 | Morphine addiction_Homo sapiens_hsa05032 | 0.91430567 |
| 43 | Long-term depression_Homo sapiens_hsa04730 | 0.89586682 |
| 44 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.88964535 |
| 45 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.87152494 |
| 46 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.84990091 |
| 47 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.80016063 |
| 48 | Focal adhesion_Homo sapiens_hsa04510 | 0.76142090 |
| 49 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.75744727 |
| 50 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.73604826 |
| 51 | GABAergic synapse_Homo sapiens_hsa04727 | 0.72145009 |
| 52 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.71346629 |
| 53 | Phagosome_Homo sapiens_hsa04145 | 0.71277968 |
| 54 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.68775082 |
| 55 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.66658064 |
| 56 | Phototransduction_Homo sapiens_hsa04744 | 0.64362444 |
| 57 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.64357943 |
| 58 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.62822873 |
| 59 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.62365369 |
| 60 | Retinol metabolism_Homo sapiens_hsa00830 | 0.61264308 |
| 61 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.60924611 |
| 62 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.60042323 |
| 63 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.59932498 |
| 64 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.59871306 |
| 65 | Malaria_Homo sapiens_hsa05144 | 0.57206078 |
| 66 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.56980202 |
| 67 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.54613499 |
| 68 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.51901494 |
| 69 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.51774626 |
| 70 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.51746863 |
| 71 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.51266168 |
| 72 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.49610418 |
| 73 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.49530863 |
| 74 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.49020734 |
| 75 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.48912799 |
| 76 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.48844493 |
| 77 | Renin secretion_Homo sapiens_hsa04924 | 0.47650804 |
| 78 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.47007924 |
| 79 | Melanoma_Homo sapiens_hsa05218 | 0.46849889 |
| 80 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.46254308 |
| 81 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.44319711 |
| 82 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.43875457 |
| 83 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.43842521 |
| 84 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.43567926 |
| 85 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.41877614 |
| 86 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.39717376 |
| 87 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.39344643 |
| 88 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.37410594 |
| 89 | Endometrial cancer_Homo sapiens_hsa05213 | 0.37330598 |
| 90 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.36119570 |
| 91 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.36003062 |
| 92 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.34424436 |
| 93 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.34350320 |
| 94 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.34089113 |
| 95 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.33710403 |
| 96 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.33682802 |
| 97 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.33616252 |
| 98 | Thyroid cancer_Homo sapiens_hsa05216 | 0.32669985 |
| 99 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.31641415 |
| 100 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.29466179 |

