GSTA6P

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein neddylation (GO:0045116)9.41215091
2thrombin receptor signaling pathway (GO:0070493)7.87901074
3neutrophil activation involved in immune response (GO:0002283)7.12396640
4triglyceride-rich lipoprotein particle remodeling (GO:0034370)7.07072836
5blood coagulation, intrinsic pathway (GO:0007597)6.11472700
6regulation of platelet aggregation (GO:0090330)5.93966099
7regulation of platelet activation (GO:0010543)5.92106229
8adenosine receptor signaling pathway (GO:0001973)5.85740147
9negative regulation of norepinephrine secretion (GO:0010700)5.63624362
10leukocyte migration involved in inflammatory response (GO:0002523)5.63539153
11low-density lipoprotein particle remodeling (GO:0034374)5.53677121
12regulation of integrin-mediated signaling pathway (GO:2001044)5.45124894
13negative regulation of heart rate (GO:0010459)5.34933779
14negative regulation of thymocyte apoptotic process (GO:0070244)5.28516552
15platelet aggregation (GO:0070527)5.27620967
16negative regulation of platelet activation (GO:0010544)5.26593354
17negative regulation of homotypic cell-cell adhesion (GO:0034111)5.12422612
18negative regulation of macrophage derived foam cell differentiation (GO:0010745)5.00045921
19lipoxygenase pathway (GO:0019372)4.87879706
20beta-amyloid metabolic process (GO:0050435)4.71324105
21positive regulation of endothelial cell differentiation (GO:0045603)4.54213227
22fusion of sperm to egg plasma membrane (GO:0007342)4.46023272
23G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)4.42943214
24high-density lipoprotein particle remodeling (GO:0034375)4.38932543
25platelet degranulation (GO:0002576)4.30314654
26negative regulation of response to food (GO:0032096)4.27350768
27negative regulation of appetite (GO:0032099)4.27350768
28purinergic nucleotide receptor signaling pathway (GO:0035590)4.19827908
29negative regulation of protein localization to cell surface (GO:2000009)4.17589923
30regulation of Golgi to plasma membrane protein transport (GO:0042996)4.17544823
31positive regulation of mast cell activation (GO:0033005)4.10476552
32neutrophil activation (GO:0042119)4.08842508
33reverse cholesterol transport (GO:0043691)4.07381442
34regulation of norepinephrine secretion (GO:0014061)4.04207401
35angiogenesis involved in wound healing (GO:0060055)4.01921338
36positive regulation of cAMP-mediated signaling (GO:0043950)3.98065730
37regulation of integrin activation (GO:0033623)3.97540993
38phospholipid homeostasis (GO:0055091)3.95797132
39regulation of lipoprotein metabolic process (GO:0050746)3.94773177
40positive regulation of systemic arterial blood pressure (GO:0003084)3.90547521
41polyamine biosynthetic process (GO:0006596)3.85613593
42positive regulation of Rho protein signal transduction (GO:0035025)3.82921527
43platelet formation (GO:0030220)3.82414885
44positive regulation of mitochondrial calcium ion concentration (GO:0051561)3.79387338
45negative regulation of hematopoietic progenitor cell differentiation (GO:1901533)3.78705653
46regulation of macrophage derived foam cell differentiation (GO:0010743)3.78612742
47extracellular fibril organization (GO:0043206)3.78600021
48positive regulation of macrophage differentiation (GO:0045651)3.78078424
49platelet activation (GO:0030168)3.74183504
50negative regulation of heart contraction (GO:0045822)3.71254560
51long-chain fatty acid biosynthetic process (GO:0042759)3.65161133
52purinergic receptor signaling pathway (GO:0035587)3.62196351
53positive regulation of receptor recycling (GO:0001921)3.61156188
54negative regulation of catecholamine secretion (GO:0033604)3.60585408
55regulation of cholesterol efflux (GO:0010874)3.60109302
56megakaryocyte development (GO:0035855)3.58007756
57homotypic cell-cell adhesion (GO:0034109)3.57817641
58regulation of homotypic cell-cell adhesion (GO:0034110)3.56466357
59granulocyte activation (GO:0036230)3.55604958
60positive regulation of blood coagulation (GO:0030194)3.51924501
61positive regulation of hemostasis (GO:1900048)3.51924501
62erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.50974042
63L-phenylalanine catabolic process (GO:0006559)3.50974042
64G-protein coupled purinergic receptor signaling pathway (GO:0035588)3.47827639
65negative regulation of neural precursor cell proliferation (GO:2000178)3.44829416
66negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)3.43548085
67regulation of female receptivity (GO:0045924)3.30840274
68termination of G-protein coupled receptor signaling pathway (GO:0038032)3.26721815
69negative regulation of T cell apoptotic process (GO:0070233)3.26659127
70plasma membrane fusion (GO:0045026)3.25193621
71regulation of MHC class II biosynthetic process (GO:0045346)3.24149454
72mitochondrial calcium ion transport (GO:0006851)3.21273728
73termination of signal transduction (GO:0023021)3.16445552
74positive regulation of coagulation (GO:0050820)3.14169844
75regulation of receptor recycling (GO:0001919)3.11166086
76fibril organization (GO:0097435)3.10481271
77autophagic vacuole fusion (GO:0000046)3.09618030
78regulation of hemostasis (GO:1900046)3.09207800
79regulation of blood coagulation (GO:0030193)3.09207800
80regulation of endothelial cell differentiation (GO:0045601)3.06536554
81tyrosine metabolic process (GO:0006570)3.04715994
82vesicle targeting (GO:0006903)2.97141915
83sequestering of actin monomers (GO:0042989)2.95851646
84cellular biogenic amine biosynthetic process (GO:0042401)2.95439734
85dopamine transport (GO:0015872)2.95332391
86negative regulation of calcium ion transport into cytosol (GO:0010523)2.95096514
87negative regulation of calcium ion transmembrane transport (GO:1903170)2.93722321
88negative regulation of calcium ion transmembrane transporter activity (GO:1901020)2.93722321
89positive regulation of protein homodimerization activity (GO:0090073)2.91825060
90L-phenylalanine metabolic process (GO:0006558)2.91672351
91erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)2.91672351
92negative regulation of blood coagulation (GO:0030195)2.90356800
93negative regulation of hemostasis (GO:1900047)2.90356800
94female mating behavior (GO:0060180)2.87169261
95monoamine transport (GO:0015844)2.87126715
96fatty acid elongation (GO:0030497)2.87103733
97leukocyte degranulation (GO:0043299)2.86882204
98negative regulation of protein localization to plasma membrane (GO:1903077)2.85805963
99relaxation of smooth muscle (GO:0044557)2.84631957
100negative regulation of T-helper cell differentiation (GO:0045623)2.84043761

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human5.10349108
2LYL1_20887958_ChIP-Seq_HPC-7_Mouse4.52194098
3SCL_19346495_ChIP-Seq_HPC-7_Human3.70441817
4EZH2_22144423_ChIP-Seq_EOC_Human3.44532284
5GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human3.13521946
6RUNX1_20887958_ChIP-Seq_HPC-7_Mouse3.10514411
7SRY_22984422_ChIP-ChIP_TESTIS_Rat3.07123846
8GATA1_19941826_ChIP-Seq_K562_Human2.87656858
9LMO2_20887958_ChIP-Seq_HPC-7_Mouse2.82843984
10MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.80291225
11GATA2_19941826_ChIP-Seq_K562_Human2.50429860
12HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.49720010
13FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.47800220
14GATA1_19941827_ChIP-Seq_MEL_Mouse2.41815387
15GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.38723181
16HTT_18923047_ChIP-ChIP_STHdh_Human2.36820017
17Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.27411676
18GBX2_23144817_ChIP-Seq_PC3_Human2.24548636
19PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.19948885
20GATA2_21666600_ChIP-Seq_HMVEC_Human2.19637066
21GATA2_20887958_ChIP-Seq_HPC-7_Mouse2.15310198
22IRF8_21731497_ChIP-ChIP_J774_Mouse2.07160902
23CDX2_19796622_ChIP-Seq_MESCs_Mouse2.00024816
24ELK4_26923725_Chip-Seq_MESODERM_Mouse1.98963072
25SPI1_23127762_ChIP-Seq_K562_Human1.97349316
26TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.94783173
27IKZF1_21737484_ChIP-ChIP_HCT116_Human1.93936961
28GATA1_22383799_ChIP-Seq_G1ME_Mouse1.92297492
29TAF15_26573619_Chip-Seq_HEK293_Human1.82116940
30MYB_21317192_ChIP-Seq_ERMYB_Mouse1.77828927
31GATA1_22025678_ChIP-Seq_K562_Human1.65123452
32MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.64874612
33RUNX1_22412390_ChIP-Seq_EML_Mouse1.52740836
34GATA1_19941827_ChIP-Seq_MEL86_Mouse1.49032657
35IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.44023841
36PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.43456389
37IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.42908098
38NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.40977008
39NRF2_20460467_ChIP-Seq_MEFs_Mouse1.40977008
40STAT6_21828071_ChIP-Seq_BEAS2B_Human1.38249762
41POU3F2_20337985_ChIP-ChIP_501MEL_Human1.37703477
42NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.37655054
43VDR_22108803_ChIP-Seq_LS180_Human1.34222422
44EGR1_23403033_ChIP-Seq_LIVER_Mouse1.34175152
45STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.33783823
46PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.31169482
47SALL4_22934838_ChIP-ChIP_CD34+_Human1.27525092
48IRF8_27001747_Chip-Seq_BMDM_Mouse1.25590958
49KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.18166417
50SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.16173247
51PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.14155931
52SPI1_20517297_ChIP-Seq_HL60_Human1.12196209
53EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.11158677
54FLI1_27457419_Chip-Seq_LIVER_Mouse1.10632230
55BCAT_22108803_ChIP-Seq_LS180_Human1.08105994
56ETS1_22383799_ChIP-Seq_G1ME_Mouse1.05885699
57GATA2_22383799_ChIP-Seq_G1ME_Mouse1.05129103
58UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.04482429
59LMO2_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.03178269
60RUNX_20019798_ChIP-Seq_JUKART_Human1.00958515
61TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.00804888
62STAT1_20625510_ChIP-Seq_HELA_Human0.99387307
63GATA3_21878914_ChIP-Seq_MCF-7_Human0.97755511
64EZH2_27294783_Chip-Seq_NPCs_Mouse0.97010640
65OCT1_27270436_Chip-Seq_PROSTATE_Human0.94743585
66ESR1_20079471_ChIP-ChIP_T-47D_Human0.93609333
67TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.91867425
68TCF4_18268006_ChIP-ChIP_LS174T_Human0.91728565
69SUZ12_27294783_Chip-Seq_NPCs_Mouse0.91668189
70GATA4_25053715_ChIP-Seq_YYC3_Human0.91655083
71P53_22387025_ChIP-Seq_ESCs_Mouse0.91292555
72EWS_26573619_Chip-Seq_HEK293_Human0.91080529
73AR_25329375_ChIP-Seq_VCAP_Human0.90180898
74SMAD4_21799915_ChIP-Seq_A2780_Human0.89712750
75AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.88095934
76ERG_20517297_ChIP-Seq_VCAP_Human0.87192549
77IGF1R_20145208_ChIP-Seq_DFB_Human0.86711065
78SOX2_20726797_ChIP-Seq_SW620_Human0.85847323
79FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.84983473
80SOX2_19829295_ChIP-Seq_ESCs_Human0.82772168
81NANOG_19829295_ChIP-Seq_ESCs_Human0.82772168
82NCOR1_26117541_ChIP-Seq_K562_Human0.82026448
83JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.80252834
84HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.80178940
85OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.79548651
86PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.78911452
87AR_20517297_ChIP-Seq_VCAP_Human0.78007727
88IRF1_19129219_ChIP-ChIP_H3396_Human0.77935639
89NFE2_27457419_Chip-Seq_LIVER_Mouse0.77826644
90PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.77472902
91NANOG_20526341_ChIP-Seq_ESCs_Human0.77104453
92JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.76217206
93PU1_27457419_Chip-Seq_LIVER_Mouse0.76012244
94GATA3_26560356_Chip-Seq_TH2_Human0.74724787
95SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.74603094
96CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.73475492
97CRX_20693478_ChIP-Seq_RETINA_Mouse0.73455660
98RUNX1_27457419_Chip-Seq_LIVER_Mouse0.73187545
99SOX2_22085726_ChIP-Seq_NPCs_Mouse0.73156715
100OCT4_21477851_ChIP-Seq_ESCs_Mouse0.72508660

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008004_abnormal_stomach_pH5.01236595
2MP0003724_increased_susceptibility_to3.53973451
3MP0000465_gastrointestinal_hemorrhage3.06604693
4MP0000343_altered_response_to2.47976343
5MP0000230_abnormal_systemic_arterial2.40831630
6MP0004510_myositis2.35595086
7MP0002736_abnormal_nociception_after2.31132900
8MP0003566_abnormal_cell_adhesion2.24583579
9MP0001879_abnormal_lymphatic_vessel2.17828613
10MP0005410_abnormal_fertilization2.15925919
11MP0001835_abnormal_antigen_presentation2.14891784
12MP0005083_abnormal_biliary_tract2.10183417
13MP0005084_abnormal_gallbladder_morpholo2.05575247
14MP0008872_abnormal_physiological_respon2.03367645
15MP0005464_abnormal_platelet_physiology10.6077637
16MP0003303_peritoneal_inflammation1.98853200
17MP0005167_abnormal_blood-brain_barrier1.96953913
18MP0003638_abnormal_response/metabolism_1.95113276
19MP0003879_abnormal_hair_cell1.93119612
20MP0004084_abnormal_cardiac_muscle1.92584026
21MP0005646_abnormal_pituitary_gland1.84309738
22MP0008775_abnormal_heart_ventricle1.79316597
23MP0005058_abnormal_lysosome_morphology1.74110819
24MP0003828_pulmonary_edema1.65048505
25MP0004130_abnormal_muscle_cell1.60855487
26MP0010155_abnormal_intestine_physiology1.60098033
27MP0005671_abnormal_response_to1.53427717
28MP0010329_abnormal_lipoprotein_level1.52934768
29MP0002733_abnormal_thermal_nociception1.47236941
30MP0002148_abnormal_hypersensitivity_rea1.46233637
31MP0009780_abnormal_chondrocyte_physiolo1.42189654
32MP0001968_abnormal_touch/_nociception1.42017740
33MP0002132_abnormal_respiratory_system1.39715971
34MP0004036_abnormal_muscle_relaxation1.38955893
35MP0001851_eye_inflammation1.38293019
36MP0004215_abnormal_myocardial_fiber1.32927946
37MP0000249_abnormal_blood_vessel1.31661513
38MP0009697_abnormal_copulation1.30747080
39MP0001545_abnormal_hematopoietic_system1.25575246
40MP0005397_hematopoietic_system_phenotyp1.25575246
41MP0001663_abnormal_digestive_system1.25269243
42MP0009763_increased_sensitivity_to1.21951189
43MP0005000_abnormal_immune_tolerance1.21890917
44MP0002398_abnormal_bone_marrow1.18683558
45MP0004947_skin_inflammation1.17961676
46MP0003136_yellow_coat_color1.09350361
47MP0006276_abnormal_autonomic_nervous1.08679686
48MP0008874_decreased_physiological_sensi1.07872633
49MP0009642_abnormal_blood_homeostasis1.05387607
50MP0003656_abnormal_erythrocyte_physiolo1.00821733
51MP0003011_delayed_dark_adaptation0.99125674
52MP0001533_abnormal_skeleton_physiology0.98594558
53MP0000015_abnormal_ear_pigmentation0.97598858
54MP0001970_abnormal_pain_threshold0.96468049
55MP0001765_abnormal_ion_homeostasis0.93554512
56MP0000858_altered_metastatic_potential0.91871481
57MP0002723_abnormal_immune_serum0.91038454
58MP0003866_abnormal_defecation0.90892541
59MP0009765_abnormal_xenobiotic_induced0.90745352
60MP0002972_abnormal_cardiac_muscle0.88753571
61MP0006054_spinal_hemorrhage0.88571984
62MP0006036_abnormal_mitochondrial_physio0.88549491
63MP0009764_decreased_sensitivity_to0.87637141
64MP0005501_abnormal_skin_physiology0.85263276
65MP0002429_abnormal_blood_cell0.85092861
66MP0004134_abnormal_chest_morphology0.83646928
67MP0006138_congestive_heart_failure0.82844387
68MP0005165_increased_susceptibility_to0.82444091
69MP0005385_cardiovascular_system_phenoty0.81624962
70MP0001544_abnormal_cardiovascular_syste0.81624962
71MP0000689_abnormal_spleen_morphology0.81296290
72MP0001800_abnormal_humoral_immune0.80129584
73MP0005647_abnormal_sex_gland0.79782216
74MP0001756_abnormal_urination0.79559322
75MP0003186_abnormal_redox_activity0.79087435
76MP0005381_digestive/alimentary_phenotyp0.78980754
77MP0002452_abnormal_antigen_presenting0.78427165
78MP0002118_abnormal_lipid_homeostasis0.78084888
79MP0001664_abnormal_digestion0.77360699
80MP0005187_abnormal_penis_morphology0.77173225
81MP0005409_darkened_coat_color0.75720101
82MP0000383_abnormal_hair_follicle0.72933658
83MP0001845_abnormal_inflammatory_respons0.71440393
84MP0002735_abnormal_chemical_nociception0.71332669
85MP0005365_abnormal_bile_salt0.70550021
86MP0002722_abnormal_immune_system0.68940360
87MP0005620_abnormal_muscle_contractility0.68008804
88MP0002877_abnormal_melanocyte_morpholog0.67966507
89MP0002128_abnormal_blood_circulation0.67907816
90MP0003436_decreased_susceptibility_to0.67228070
91MP0005023_abnormal_wound_healing0.66513072
92MP0002653_abnormal_ependyma_morphology0.66489622
93MP0000358_abnormal_cell_content/0.66198861
94MP0002998_abnormal_bone_remodeling0.66017194
95MP0004272_abnormal_basement_membrane0.65174774
96MP0005174_abnormal_tail_pigmentation0.65014989
97MP0009333_abnormal_splenocyte_physiolog0.64989659
98MP0005666_abnormal_adipose_tissue0.64770220
99MP0004085_abnormal_heartbeat0.64535401
100MP0002420_abnormal_adaptive_immunity0.63874736

Predicted human phenotypes

RankGene SetZ-score
1Abnormal platelet volume (HP:0011876)9.64320885
2Petechiae (HP:0000967)9.50009473
3Purpura (HP:0000979)8.76491454
4Epistaxis (HP:0000421)7.72044429
5Hyperlipoproteinemia (HP:0010980)7.48204055
6Gingival bleeding (HP:0000225)6.59318588
7Abnormal platelet function (HP:0011869)5.40321418
8Impaired platelet aggregation (HP:0003540)5.40321418
9Dyschromatopsia (HP:0007641)4.31397738
10Poikilocytosis (HP:0004447)4.27881051
11Acanthocytosis (HP:0001927)4.18071633
12Abnormal pupillary function (HP:0007686)3.74754968
13Abnormality of the common coagulation pathway (HP:0010990)3.74189043
14Conjunctival telangiectasia (HP:0000524)3.74163605
15Paralysis (HP:0003470)3.68194870
16Spontaneous hematomas (HP:0007420)3.64982879
17Abnormality of lateral ventricle (HP:0030047)3.38047420
18Abnormality of the heme biosynthetic pathway (HP:0010472)3.36482443
19Bruising susceptibility (HP:0000978)3.35626144
20Abnormality of the vasculature of the conjunctiva (HP:0008054)3.27019570
21Xanthomatosis (HP:0000991)3.02771056
22Increased density of long bones (HP:0006392)2.88647920
23Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.83178463
24Joint swelling (HP:0001386)2.77937663
25Abnormal auditory evoked potentials (HP:0006958)2.70435915
26Joint hemorrhage (HP:0005261)2.67866908
27Hepatosplenomegaly (HP:0001433)2.66131004
28Upper limb muscle weakness (HP:0003484)2.56493078
29Male infertility (HP:0003251)2.56327609
30Decreased central vision (HP:0007663)2.56241195
31Generalized aminoaciduria (HP:0002909)2.54738058
32Spontaneous abortion (HP:0005268)2.49747533
33Abnormal ciliary motility (HP:0012262)2.42638071
34Thyroid-stimulating hormone excess (HP:0002925)2.41856298
35Nausea (HP:0002018)2.39914802
36Papillary thyroid carcinoma (HP:0002895)2.38253871
37Increased IgM level (HP:0003496)2.34551626
38Stomatitis (HP:0010280)2.28585981
39Tinnitus (HP:0000360)2.27667110
40Ventricular fibrillation (HP:0001663)2.12831177
41Dysautonomia (HP:0002459)2.10464038
423-Methylglutaconic aciduria (HP:0003535)2.09689680
43Abnormality of iron homeostasis (HP:0011031)2.08386609
44Abnormality of macrophages (HP:0004311)2.07994159
45Abnormal respiratory epithelium morphology (HP:0012253)2.06369120
46Abnormal respiratory motile cilium morphology (HP:0005938)2.06369120
47Hypophosphatemic rickets (HP:0004912)2.04945238
48Prolonged bleeding time (HP:0003010)11.5874806
49Menorrhagia (HP:0000132)10.9224031
50Increased mean platelet volume (HP:0011877)10.3328899
51Biliary tract neoplasm (HP:0100574)1.99061855
52Infertility (HP:0000789)1.92503816
53Tongue fasciculations (HP:0001308)1.90740227
54Abnormality of transition element cation homeostasis (HP:0011030)1.85972982
55Arthropathy (HP:0003040)1.84335067
56Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.81209284
57Abnormality of alanine metabolism (HP:0010916)1.81209284
58Hyperalaninemia (HP:0003348)1.81209284
59Episodic fever (HP:0001954)1.79045455
60Absent/shortened dynein arms (HP:0200106)1.75628032
61Dynein arm defect of respiratory motile cilia (HP:0012255)1.75628032
62Myocardial infarction (HP:0001658)1.75437789
63Basal ganglia calcification (HP:0002135)1.70879078
64Encephalitis (HP:0002383)1.69292533
65Hyperthyroidism (HP:0000836)1.69202152
66Muscle fibrillation (HP:0010546)1.68774632
67Abnormality of the prostate (HP:0008775)1.68441989
68Distal lower limb amyotrophy (HP:0008944)1.66339907
69Thyroid carcinoma (HP:0002890)1.66208069
70Abnormal respiratory motile cilium physiology (HP:0012261)1.65760633
71Mitral stenosis (HP:0001718)1.65449692
72Arterial thrombosis (HP:0004420)1.65168853
73Transitional cell carcinoma of the bladder (HP:0006740)1.63514407
74Leiomyosarcoma (HP:0100243)1.62736477
75Uterine leiomyosarcoma (HP:0002891)1.62736477
76Polyphagia (HP:0002591)1.62665168
77Increased serum ferritin (HP:0003281)1.62578906
78Renal Fanconi syndrome (HP:0001994)1.60785993
79Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.57628459
80Testicular neoplasm (HP:0010788)1.55926590
81Polycythemia (HP:0001901)1.52071649
82Vertigo (HP:0002321)1.50910133
83Back pain (HP:0003418)1.48332293
84Autoimmune hemolytic anemia (HP:0001890)1.46556386
85Abnormal spermatogenesis (HP:0008669)1.46285379
86Bladder neoplasm (HP:0009725)1.45450244
87Bladder carcinoma (HP:0002862)1.45450244
88Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.42730631
89Exertional dyspnea (HP:0002875)1.40249312
90Vascular calcification (HP:0004934)1.38650534
91Congenital sensorineural hearing impairment (HP:0008527)1.38334611
92Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.36766792
93Central scotoma (HP:0000603)1.36147004
94Neoplasm of the rectum (HP:0100743)1.35162294
95Abnormality of the Achilles tendon (HP:0005109)1.34214016
96Chronic obstructive pulmonary disease (HP:0006510)1.32609358
97Obstructive lung disease (HP:0006536)1.32609358
98Ileus (HP:0002595)1.30342345
99Lower limb amyotrophy (HP:0007210)1.29293969
100Dysostosis multiplex (HP:0000943)1.28758675

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MST46.30304029
2BMX4.54141600
3MYLK4.07316093
4RIPK44.04670354
5BTK2.98429048
6TEC2.90663455
7PTK2B2.89816427
8EIF2AK12.70552592
9GRK52.36844549
10ILK2.32241243
11TAOK32.20964221
12CSF1R2.16914621
13PIK3CG2.08800020
14SYK2.00381700
15MAPKAPK31.97818143
16GRK61.93429305
17ZAP701.87162571
18PLK21.74762055
19STK31.72534686
20BMPR21.62955771
21FGR1.62872850
22DAPK31.34449409
23ADRBK21.34335955
24LMTK21.31133599
25PAK11.31124366
26ACVR1B1.25261336
27TLK11.19572347
28HCK1.18681952
29TNK21.16930313
30PNCK1.14328653
31IKBKB1.12293680
32DAPK21.11955400
33PIM21.10651510
34TRIM281.10613985
35TNIK1.07115937
36LYN1.06152462
37EPHB21.03718720
38BLK0.98899620
39EPHA30.95595393
40NUAK10.88733995
41MATK0.86169128
42FES0.85479573
43ADRBK10.85330996
44ERBB20.84753972
45STK240.84316570
46MAP4K20.81740999
47FER0.81639407
48RET0.80462409
49DAPK10.78401608
50BMPR1B0.75890192
51MAP3K50.74773210
52ITK0.74426529
53PRKD10.72833470
54PKN10.72071580
55MINK10.68012378
56TXK0.63974325
57IRAK10.62903700
58MARK30.60629913
59TESK20.59942273
60STK160.56719839
61PAK30.56290494
62SIK30.56123052
63GRK10.55619620
64MAP3K120.55456979
65PRKACG0.55355926
66MAP2K30.49871234
67TAOK20.49729962
68MAPK120.49570993
69ZAK0.49569811
70STK40.47614683
71PRKG10.45520014
72ARAF0.44381774
73MAPK130.44041928
74MAP2K10.42649555
75CAMKK20.42351014
76PDK10.41571427
77BRSK20.39818921
78PDGFRB0.39735960
79ROCK10.38747474
80CSK0.38428737
81FYN0.37208636
82PRKCE0.35633064
83LCK0.32439100
84PRKCB0.32082253
85PDPK10.31409126
86PRKCA0.30624696
87CDK140.30427669
88CAMK2G0.30263606
89CAMK2A0.29620745
90IGF1R0.29338562
91PRKCD0.29018048
92TAOK10.26512301
93PRKCQ0.25051110
94SRC0.24456919
95DYRK30.22717406
96JAK20.22269188
97DYRK1A0.21196762
98PLK30.21048737
99CAMK2D0.20450167
100PRKCG0.20340937

Predicted pathways (KEGG)

RankGene SetZ-score
1Platelet activation_Homo sapiens_hsa046115.69024816
2Pathogenic Escherichia coli infection_Homo sapiens_hsa051303.77435261
3SNARE interactions in vesicular transport_Homo sapiens_hsa041303.36326583
4Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007602.69997137
5ECM-receptor interaction_Homo sapiens_hsa045122.55980144
6Nitrogen metabolism_Homo sapiens_hsa009102.53504284
7Arachidonic acid metabolism_Homo sapiens_hsa005902.50985468
8Hematopoietic cell lineage_Homo sapiens_hsa046402.18171124
9Collecting duct acid secretion_Homo sapiens_hsa049662.00691578
10Gap junction_Homo sapiens_hsa045401.95441930
11Serotonergic synapse_Homo sapiens_hsa047261.94793223
12alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.84935075
13Vascular smooth muscle contraction_Homo sapiens_hsa042701.83052330
14Sulfur metabolism_Homo sapiens_hsa009201.79991407
15Chemokine signaling pathway_Homo sapiens_hsa040621.71944006
16Alcoholism_Homo sapiens_hsa050341.66271796
17Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.58887375
18Systemic lupus erythematosus_Homo sapiens_hsa053221.55936745
19Fatty acid elongation_Homo sapiens_hsa000621.47245956
20Linoleic acid metabolism_Homo sapiens_hsa005911.47120742
21Glycerolipid metabolism_Homo sapiens_hsa005611.34254578
22Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.32348998
23Pancreatic secretion_Homo sapiens_hsa049721.32130532
24Glutathione metabolism_Homo sapiens_hsa004801.27693640
25Endocytosis_Homo sapiens_hsa041441.26451832
26Steroid hormone biosynthesis_Homo sapiens_hsa001401.24426953
27Shigellosis_Homo sapiens_hsa051311.11258706
28Regulation of actin cytoskeleton_Homo sapiens_hsa048101.08867494
29Mismatch repair_Homo sapiens_hsa034301.08069669
30Fat digestion and absorption_Homo sapiens_hsa049751.04584876
31Pentose and glucuronate interconversions_Homo sapiens_hsa000401.04075016
32Olfactory transduction_Homo sapiens_hsa047401.03881719
33Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.00137664
34Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.98080334
35Starch and sucrose metabolism_Homo sapiens_hsa005000.97861548
36Circadian entrainment_Homo sapiens_hsa047130.97685152
37Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.96896929
38Chemical carcinogenesis_Homo sapiens_hsa052040.93782545
39Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.93369732
40Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.92261601
41Phospholipase D signaling pathway_Homo sapiens_hsa040720.92065008
42Morphine addiction_Homo sapiens_hsa050320.91430567
43Long-term depression_Homo sapiens_hsa047300.89586682
44Renin-angiotensin system_Homo sapiens_hsa046140.88964535
45Leukocyte transendothelial migration_Homo sapiens_hsa046700.87152494
46B cell receptor signaling pathway_Homo sapiens_hsa046620.84990091
47Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.80016063
48Focal adhesion_Homo sapiens_hsa045100.76142090
49Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.75744727
50Primary bile acid biosynthesis_Homo sapiens_hsa001200.73604826
51GABAergic synapse_Homo sapiens_hsa047270.72145009
52Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.71346629
53Phagosome_Homo sapiens_hsa041450.71277968
54T cell receptor signaling pathway_Homo sapiens_hsa046600.68775082
55Rap1 signaling pathway_Homo sapiens_hsa040150.66658064
56Phototransduction_Homo sapiens_hsa047440.64362444
57Primary immunodeficiency_Homo sapiens_hsa053400.64357943
58Complement and coagulation cascades_Homo sapiens_hsa046100.62822873
59Calcium signaling pathway_Homo sapiens_hsa040200.62365369
60Retinol metabolism_Homo sapiens_hsa008300.61264308
61Ras signaling pathway_Homo sapiens_hsa040140.60924611
62PPAR signaling pathway_Homo sapiens_hsa033200.60042323
63Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.59932498
64Glycerophospholipid metabolism_Homo sapiens_hsa005640.59871306
65Malaria_Homo sapiens_hsa051440.57206078
66Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.56980202
67Choline metabolism in cancer_Homo sapiens_hsa052310.54613499
68Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.51901494
69beta-Alanine metabolism_Homo sapiens_hsa004100.51774626
70Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.51746863
71Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.51266168
72Synaptic vesicle cycle_Homo sapiens_hsa047210.49610418
73Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.49530863
74Viral carcinogenesis_Homo sapiens_hsa052030.49020734
75Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.48912799
76Cholinergic synapse_Homo sapiens_hsa047250.48844493
77Renin secretion_Homo sapiens_hsa049240.47650804
78Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.47007924
79Melanoma_Homo sapiens_hsa052180.46849889
80Tyrosine metabolism_Homo sapiens_hsa003500.46254308
81Sphingolipid metabolism_Homo sapiens_hsa006000.44319711
82Steroid biosynthesis_Homo sapiens_hsa001000.43875457
83Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.43842521
84cGMP-PKG signaling pathway_Homo sapiens_hsa040220.43567926
85Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.41877614
86Dilated cardiomyopathy_Homo sapiens_hsa054140.39717376
87Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.39344643
88Gastric acid secretion_Homo sapiens_hsa049710.37410594
89Endometrial cancer_Homo sapiens_hsa052130.37330598
90Glutamatergic synapse_Homo sapiens_hsa047240.36119570
91Phosphatidylinositol signaling system_Homo sapiens_hsa040700.36003062
92Drug metabolism - other enzymes_Homo sapiens_hsa009830.34424436
93Pentose phosphate pathway_Homo sapiens_hsa000300.34350320
94Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.34089113
95Staphylococcus aureus infection_Homo sapiens_hsa051500.33710403
96Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.33682802
97Small cell lung cancer_Homo sapiens_hsa052220.33616252
98Thyroid cancer_Homo sapiens_hsa052160.32669985
99Toll-like receptor signaling pathway_Homo sapiens_hsa046200.31641415
100Regulation of autophagy_Homo sapiens_hsa041400.29466179

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »