GSTCD

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)4.98462458
2protein localization to kinetochore (GO:0034501)4.75872159
3nuclear pore organization (GO:0006999)4.61712093
4nuclear pore complex assembly (GO:0051292)4.58693421
5mitotic nuclear envelope disassembly (GO:0007077)4.16077288
6protein localization to chromosome, centromeric region (GO:0071459)4.14673823
7DNA strand elongation involved in DNA replication (GO:0006271)4.04013853
8DNA replication initiation (GO:0006270)3.97509417
9mitotic metaphase plate congression (GO:0007080)3.95143613
10folic acid-containing compound biosynthetic process (GO:0009396)3.93058250
11replication fork processing (GO:0031297)3.87539724
12membrane disassembly (GO:0030397)3.87303413
13nuclear envelope disassembly (GO:0051081)3.87303413
14DNA strand elongation (GO:0022616)3.83086000
15IMP biosynthetic process (GO:0006188)3.77754048
16sister chromatid segregation (GO:0000819)3.77043944
17mitotic sister chromatid cohesion (GO:0007064)3.76786542
18DNA replication-dependent nucleosome assembly (GO:0006335)3.76611281
19DNA replication-dependent nucleosome organization (GO:0034723)3.76611281
20mitotic chromosome condensation (GO:0007076)3.76474505
21mitotic sister chromatid segregation (GO:0000070)3.70972102
22DNA double-strand break processing (GO:0000729)3.62510691
23DNA geometric change (GO:0032392)3.62183249
24DNA duplex unwinding (GO:0032508)3.60779619
25telomere maintenance via semi-conservative replication (GO:0032201)3.58469088
26somatic diversification of immune receptors via somatic mutation (GO:0002566)3.53647480
27somatic hypermutation of immunoglobulin genes (GO:0016446)3.53647480
28metaphase plate congression (GO:0051310)3.49379774
29regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.47521916
30kinetochore organization (GO:0051383)3.47511203
31nucleobase biosynthetic process (GO:0046112)3.44644337
32DNA ligation (GO:0006266)3.41245785
33mitotic recombination (GO:0006312)3.40250814
34IMP metabolic process (GO:0046040)3.40111533
35ribosomal small subunit assembly (GO:0000028)3.37521483
36pore complex assembly (GO:0046931)3.37132691
37chromatin remodeling at centromere (GO:0031055)3.36786084
38regulation of histone H3-K9 methylation (GO:0051570)3.36256414
39telomere maintenance via recombination (GO:0000722)3.36056702
40formation of translation preinitiation complex (GO:0001731)3.34108928
41maturation of SSU-rRNA (GO:0030490)3.33616813
42regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.33483383
43DNA replication checkpoint (GO:0000076)3.31118545
44CENP-A containing nucleosome assembly (GO:0034080)3.30908913
45non-recombinational repair (GO:0000726)3.30220609
46double-strand break repair via nonhomologous end joining (GO:0006303)3.30220609
47meiotic chromosome segregation (GO:0045132)3.29208431
48maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.26218611
49regulation of spindle organization (GO:0090224)3.24465946
50DNA replication-independent nucleosome organization (GO:0034724)3.23061758
51DNA replication-independent nucleosome assembly (GO:0006336)3.23061758
52heterochromatin organization (GO:0070828)3.20358663
53negative regulation of DNA-dependent DNA replication (GO:2000104)3.19848240
54regulation of centriole replication (GO:0046599)3.18055591
55water-soluble vitamin biosynthetic process (GO:0042364)3.17939558
56regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.15766940
57regulation of mitotic spindle checkpoint (GO:1903504)3.15766940
58establishment of chromosome localization (GO:0051303)3.15364153
59regulation of centrosome cycle (GO:0046605)3.15248755
60negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.12915139
61establishment of integrated proviral latency (GO:0075713)3.11596164
62negative regulation of histone methylation (GO:0031061)3.10114461
63chromatin assembly or disassembly (GO:0006333)3.09836722
64DNA conformation change (GO:0071103)3.09558131
65positive regulation of chromosome segregation (GO:0051984)3.09350692
66attachment of spindle microtubules to kinetochore (GO:0008608)3.08230167
67dosage compensation (GO:0007549)3.07070853
68negative regulation of RNA splicing (GO:0033119)3.06319813
69synapsis (GO:0007129)3.05709219
70nuclear envelope organization (GO:0006998)3.04348930
71purine nucleobase biosynthetic process (GO:0009113)3.01810567
72RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.99616074
73translesion synthesis (GO:0019985)2.99526746
74chromatin assembly (GO:0031497)2.98809288
75regulation of sister chromatid cohesion (GO:0007063)2.97901814
76regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.97366006
77ribosome assembly (GO:0042255)2.97200884
78histone exchange (GO:0043486)2.97164702
79postreplication repair (GO:0006301)2.96521011
80recombinational repair (GO:0000725)2.96042398
81double-strand break repair via homologous recombination (GO:0000724)2.95719965
82microtubule depolymerization (GO:0007019)2.94945197
83telomere maintenance via telomere lengthening (GO:0010833)2.94849790
84positive regulation of mitotic sister chromatid separation (GO:1901970)2.94640040
85positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.94640040
86positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.94640040
87protein localization to chromosome (GO:0034502)2.94579750
88viral transcription (GO:0019083)2.94573889
89chromosome condensation (GO:0030261)2.93105236
90translational termination (GO:0006415)2.92512944
91RNA stabilization (GO:0043489)2.91519160
92mRNA stabilization (GO:0048255)2.91519160
93maturation of 5.8S rRNA (GO:0000460)2.91205302
94pre-miRNA processing (GO:0031054)2.91025598
95nucleotide-excision repair, DNA gap filling (GO:0006297)2.90687025
96DNA topological change (GO:0006265)2.90320193
97ATP-dependent chromatin remodeling (GO:0043044)2.87586603
98nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.85698264
99somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.82868293
100somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.82868293
101isotype switching (GO:0045190)2.82868293
102exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.82087257
103regulation of mitotic spindle organization (GO:0060236)2.82042450
104regulation of chromosome segregation (GO:0051983)2.81268037
105translational initiation (GO:0006413)2.79288781
106kinetochore assembly (GO:0051382)2.79238056
107regulation of gene silencing by RNA (GO:0060966)2.79217899
108regulation of posttranscriptional gene silencing (GO:0060147)2.79217899
109regulation of gene silencing by miRNA (GO:0060964)2.79217899
110negative regulation of mRNA processing (GO:0050686)2.79126497
111somatic recombination of immunoglobulin gene segments (GO:0016447)2.77358194
112negative regulation of DNA recombination (GO:0045910)2.77215978
113centriole replication (GO:0007099)2.77125515
114regulation of translational fidelity (GO:0006450)2.77039307
115somatic diversification of immunoglobulins (GO:0016445)2.76596842
1163-UTR-mediated mRNA stabilization (GO:0070935)2.75989251
117translational elongation (GO:0006414)2.74798894
118regulation of helicase activity (GO:0051095)2.74304592
119protein K6-linked ubiquitination (GO:0085020)2.73500073
120regulation of DNA endoreduplication (GO:0032875)2.72726021
121nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.72200534
122regulation of centrosome duplication (GO:0010824)2.72060716
123chromosome segregation (GO:0007059)2.70852305
124reciprocal DNA recombination (GO:0035825)2.70724317
125reciprocal meiotic recombination (GO:0007131)2.70724317
126DNA packaging (GO:0006323)2.70303750
127regulation of telomere maintenance via telomerase (GO:0032210)2.70295015
128regulation of nuclear cell cycle DNA replication (GO:0033262)2.69737970
129mitotic spindle checkpoint (GO:0071174)2.68399266
130proteasome assembly (GO:0043248)2.68090267
131spindle checkpoint (GO:0031577)2.67746817
132cullin deneddylation (GO:0010388)2.66759449
133DNA catabolic process, exonucleolytic (GO:0000738)2.66714831
134regulation of mitotic metaphase/anaphase transition (GO:0030071)2.66708557
135regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.66708557
136negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.66662411
137negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.66662411
138negative regulation of mitotic sister chromatid segregation (GO:0033048)2.66662411
139negative regulation of mitotic sister chromatid separation (GO:2000816)2.66662411
140negative regulation of sister chromatid segregation (GO:0033046)2.66662411
141regulation of sister chromatid segregation (GO:0033045)2.66420948
142regulation of mitotic sister chromatid separation (GO:0010965)2.66420948
143regulation of mitotic sister chromatid segregation (GO:0033047)2.66420948
144negative regulation of chromosome segregation (GO:0051985)2.64022299
145RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.63986845
146mRNA splicing, via spliceosome (GO:0000398)2.63986845
147ncRNA catabolic process (GO:0034661)2.63828864
148RNA splicing, via transesterification reactions (GO:0000375)2.63481779
149ribosome biogenesis (GO:0042254)2.62553826
150establishment of protein localization to mitochondrial membrane (GO:0090151)2.62449637
151histone mRNA metabolic process (GO:0008334)2.59925321
152mismatch repair (GO:0006298)2.58138792
153response to X-ray (GO:0010165)2.55702155
154double-strand break repair (GO:0006302)2.54257204
155DNA strand renaturation (GO:0000733)2.51130601

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.64494364
2FOXM1_23109430_ChIP-Seq_U2OS_Human5.30940781
3E2F4_17652178_ChIP-ChIP_JURKAT_Human4.05092608
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.78129869
5* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.41491460
6EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.14626572
7EGR1_19374776_ChIP-ChIP_THP-1_Human3.07909010
8* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.66742722
9ZNF274_21170338_ChIP-Seq_K562_Hela2.57131996
10E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.49202906
11MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.47821613
12HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.44436030
13AR_21909140_ChIP-Seq_LNCAP_Human2.43501421
14MYC_22102868_ChIP-Seq_BL_Human2.43325440
15VDR_22108803_ChIP-Seq_LS180_Human2.42738953
16* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.41874728
17HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.39406603
18FUS_26573619_Chip-Seq_HEK293_Human2.32664192
19EWS_26573619_Chip-Seq_HEK293_Human2.28103657
20* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.18000027
21E2F1_21310950_ChIP-Seq_MCF-7_Human2.17107890
22IGF1R_20145208_ChIP-Seq_DFB_Human2.17063272
23NELFA_20434984_ChIP-Seq_ESCs_Mouse2.12311254
24* POU3F2_20337985_ChIP-ChIP_501MEL_Human2.11319505
25KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.05937503
26XRN2_22483619_ChIP-Seq_HELA_Human2.02316393
27MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.87187135
28EST1_17652178_ChIP-ChIP_JURKAT_Human1.82512443
29GBX2_23144817_ChIP-Seq_PC3_Human1.79251523
30ZFP57_27257070_Chip-Seq_ESCs_Mouse1.79084915
31MYC_18940864_ChIP-ChIP_HL60_Human1.73513162
32MYCN_18555785_ChIP-Seq_MESCs_Mouse1.73347097
33ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.72855003
34GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.71595184
35ETS1_20019798_ChIP-Seq_JURKAT_Human1.69849075
36VDR_23849224_ChIP-Seq_CD4+_Human1.69204662
37CREB1_15753290_ChIP-ChIP_HEK293T_Human1.69161351
38FLI1_27457419_Chip-Seq_LIVER_Mouse1.64538129
39HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.63838215
40NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.63379333
41CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.62479090
42ELF1_17652178_ChIP-ChIP_JURKAT_Human1.60393230
43CIITA_25753668_ChIP-Seq_RAJI_Human1.58998315
44* P300_19829295_ChIP-Seq_ESCs_Human1.58412556
45TAF15_26573619_Chip-Seq_HEK293_Human1.56716114
46TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.54591473
47* TTF2_22483619_ChIP-Seq_HELA_Human1.53612140
48SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.52681283
49SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.52103625
50GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.51494075
51* FOXP3_21729870_ChIP-Seq_TREG_Human1.49305977
52ELK1_19687146_ChIP-ChIP_HELA_Human1.48616822
53* POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.48427158
54E2F1_18555785_ChIP-Seq_MESCs_Mouse1.47982898
55CTBP2_25329375_ChIP-Seq_LNCAP_Human1.47404199
56CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.46870386
57* DCP1A_22483619_ChIP-Seq_HELA_Human1.46291993
58KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.45342957
59ZFX_18555785_ChIP-Seq_MESCs_Mouse1.43279708
60VDR_21846776_ChIP-Seq_THP-1_Human1.42624408
61NANOG_18555785_ChIP-Seq_MESCs_Mouse1.42569712
62PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.42516958
63GABP_17652178_ChIP-ChIP_JURKAT_Human1.40702568
64CTBP1_25329375_ChIP-Seq_LNCAP_Human1.39894527
65JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.39862143
66TP63_19390658_ChIP-ChIP_HaCaT_Human1.39792774
67POU5F1_16153702_ChIP-ChIP_HESCs_Human1.36528645
68SALL1_21062744_ChIP-ChIP_HESCs_Human1.34959023
69IRF1_19129219_ChIP-ChIP_H3396_Human1.33180600
70KDM5A_27292631_Chip-Seq_BREAST_Human1.32896056
71SOX2_16153702_ChIP-ChIP_HESCs_Human1.30629847
72* GABP_19822575_ChIP-Seq_HepG2_Human1.30538342
73YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.27275653
74STAT3_1855785_ChIP-Seq_MESCs_Mouse1.25751253
75NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.25568379
76SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.25171760
77PCGF2_27294783_Chip-Seq_ESCs_Mouse1.23982672
78ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.23963798
79SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.22205472
80KLF4_18555785_ChIP-Seq_MESCs_Mouse1.21434641
81AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.21299701
82POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.20866077
83CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.19628143
84SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.19270447
85FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.17457986
86DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.17164909
87TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.17002504
88IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.16834388
89CBP_20019798_ChIP-Seq_JUKART_Human1.16834388
90HOXB4_20404135_ChIP-ChIP_EML_Mouse1.16677383
91TFEB_21752829_ChIP-Seq_HELA_Human1.16096244
92E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.15894158
93* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.15850331
94* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.15816089
95ER_23166858_ChIP-Seq_MCF-7_Human1.14984355
96MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.14880235
97* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.14706237
98MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.14070401
99SRF_21415370_ChIP-Seq_HL-1_Mouse1.12160580
100NANOG_16153702_ChIP-ChIP_HESCs_Human1.11043948
101EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.10563532
102ERG_20887958_ChIP-Seq_HPC-7_Mouse1.10316579
103* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.08653886
104ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.08257160
105SOX2_18555785_ChIP-Seq_MESCs_Mouse1.08021550
106UTX_26944678_Chip-Seq_JUKART_Human1.07275546
107* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.05433265
108RBPJ_22232070_ChIP-Seq_NCS_Mouse1.05372086
109STAT3_23295773_ChIP-Seq_U87_Human1.05207804
110UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.05180476
111RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.04262140
112TCF7_22412390_ChIP-Seq_EML_Mouse1.03777136
113TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.00965822
114NOTCH1_21737748_ChIP-Seq_TLL_Human1.00368090
115THAP11_20581084_ChIP-Seq_MESCs_Mouse0.99049470
116* TP53_22573176_ChIP-Seq_HFKS_Human0.98788024
117POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.98762307
118PCGF2_27294783_Chip-Seq_NPCs_Mouse0.98248306
119MAF_26560356_Chip-Seq_TH1_Human0.98004698
120PADI4_21655091_ChIP-ChIP_MCF-7_Human0.97931667
121ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.97436833
122SMAD3_21741376_ChIP-Seq_EPCs_Human0.97316067
123MYB_21317192_ChIP-Seq_ERMYB_Mouse0.97065475
124MYB_26560356_Chip-Seq_TH1_Human0.96289036
125FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.95897869
126SPI1_23547873_ChIP-Seq_NB4_Human0.95848530
127MYB_26560356_Chip-Seq_TH2_Human0.95687956
128KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.95645032
129GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.95208296
130SCL_19346495_ChIP-Seq_HPC-7_Human0.94953954
131NANOG_19829295_ChIP-Seq_ESCs_Human0.94377351
132SOX2_19829295_ChIP-Seq_ESCs_Human0.94377351
133* KLF5_20875108_ChIP-Seq_MESCs_Mouse0.94181441
134STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.93513016
135SMAD4_21799915_ChIP-Seq_A2780_Human0.93454257
136TCF4_23295773_ChIP-Seq_U87_Human0.93297982
137SUZ12_27294783_Chip-Seq_NPCs_Mouse0.93090261
138SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.92765260
139PIAS1_25552417_ChIP-Seq_VCAP_Human0.90700350
140BRD4_27068464_Chip-Seq_AML-cells_Mouse0.90391106
141* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.90180149
142KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.90075188
143GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.89631081
144NFE2_27457419_Chip-Seq_LIVER_Mouse0.89626066
145TOP2B_26459242_ChIP-Seq_MCF-7_Human0.89183597
146PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.88832094
147NANOG_21062744_ChIP-ChIP_HESCs_Human0.87321617
148SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.87187867
149* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.86051988
150CHD1_26751641_Chip-Seq_LNCaP_Human0.85826596
151TCF3_18692474_ChIP-Seq_MEFs_Mouse0.85226537
152ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.83899193
153MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.81445644
154RUNX1_22412390_ChIP-Seq_EML_Mouse0.80106402
155KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.79577978
156YY1_21170310_ChIP-Seq_MESCs_Mouse0.78947440

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.15664885
2MP0010094_abnormal_chromosome_stability4.10624837
3MP0003111_abnormal_nucleus_morphology3.80051686
4MP0004957_abnormal_blastocyst_morpholog3.46535913
5MP0003077_abnormal_cell_cycle3.41550719
6MP0008057_abnormal_DNA_replication3.19145532
7MP0010352_gastrointestinal_tract_polyps2.74665922
8MP0008007_abnormal_cellular_replicative2.56885964
9MP0002102_abnormal_ear_morphology2.44377540
10MP0002396_abnormal_hematopoietic_system2.38962164
11MP0006292_abnormal_olfactory_placode2.36741601
12MP0009697_abnormal_copulation2.35311326
13MP0008058_abnormal_DNA_repair2.30853823
14MP0010307_abnormal_tumor_latency2.26207945
15MP0001730_embryonic_growth_arrest2.21033295
16MP0000350_abnormal_cell_proliferation2.19753767
17MP0005076_abnormal_cell_differentiation2.15339159
18MP0006072_abnormal_retinal_apoptosis2.08396764
19MP0002938_white_spotting2.04155799
20MP0008932_abnormal_embryonic_tissue2.03627536
21MP0003136_yellow_coat_color1.97621037
22MP0002638_abnormal_pupillary_reflex1.96909866
23MP0004808_abnormal_hematopoietic_stem1.95534233
24MP0000569_abnormal_digit_pigmentation1.86208899
25MP0003705_abnormal_hypodermis_morpholog1.78424656
26MP0005380_embryogenesis_phenotype1.75930806
27MP0001672_abnormal_embryogenesis/_devel1.75930806
28MP0000490_abnormal_crypts_of1.75255792
29MP0001697_abnormal_embryo_size1.72772186
30MP0004197_abnormal_fetal_growth/weight/1.65403477
31MP0003984_embryonic_growth_retardation1.60270656
32MP0002084_abnormal_developmental_patter1.59865897
33MP0002085_abnormal_embryonic_tissue1.59639969
34MP0002088_abnormal_embryonic_growth/wei1.59226715
35MP0005253_abnormal_eye_physiology1.58331271
36MP0003011_delayed_dark_adaptation1.57487298
37MP0003123_paternal_imprinting1.57385390
38MP0001529_abnormal_vocalization1.55711524
39MP0002653_abnormal_ependyma_morphology1.55315749
40MP0005084_abnormal_gallbladder_morpholo1.53808100
41MP0002086_abnormal_extraembryonic_tissu1.53799902
42MP0002080_prenatal_lethality1.51722473
43MP0000372_irregular_coat_pigmentation1.48878547
44MP0005551_abnormal_eye_electrophysiolog1.47276750
45MP0003787_abnormal_imprinting1.44549981
46MP0000427_abnormal_hair_cycle1.41916793
47MP0000313_abnormal_cell_death1.38435204
48MP0010030_abnormal_orbit_morphology1.38134212
49MP0002019_abnormal_tumor_incidence1.35572549
50MP0003567_abnormal_fetal_cardiomyocyte1.35540991
51MP0001293_anophthalmia1.34629274
52MP0004133_heterotaxia1.34380445
53MP0005397_hematopoietic_system_phenotyp1.33606510
54MP0001545_abnormal_hematopoietic_system1.33606510
55MP0002234_abnormal_pharynx_morphology1.28559408
56MP0000703_abnormal_thymus_morphology1.24169895
57MP0003195_calcinosis1.24146623
58MP0002398_abnormal_bone_marrow1.23686949
59MP0000537_abnormal_urethra_morphology1.22552825
60MP0000631_abnormal_neuroendocrine_gland1.22461138
61MP0003890_abnormal_embryonic-extraembry1.20268822
62MP0003763_abnormal_thymus_physiology1.19997934
63MP0003121_genomic_imprinting1.19425658
64MP0003786_premature_aging1.17835234
65MP0009278_abnormal_bone_marrow1.17483135
66MP0009053_abnormal_anal_canal1.16692027
67MP0005645_abnormal_hypothalamus_physiol1.16422704
68MP0008877_abnormal_DNA_methylation1.16324073
69MP0002160_abnormal_reproductive_system1.16028877
70MP0000858_altered_metastatic_potential1.13781162
71MP0002751_abnormal_autonomic_nervous1.12260823
72MP0002722_abnormal_immune_system1.10689633
73MP0005391_vision/eye_phenotype1.09441676
74MP0005023_abnormal_wound_healing1.09434621
75MP0003122_maternal_imprinting1.09376825
76MP0008789_abnormal_olfactory_epithelium1.09171753
77MP0000733_abnormal_muscle_development1.08567264
78MP0000689_abnormal_spleen_morphology1.07666552
79MP0000647_abnormal_sebaceous_gland1.06625277
80MP0003566_abnormal_cell_adhesion1.05620990
81MP0000383_abnormal_hair_follicle1.04741871
82MP0001915_intracranial_hemorrhage1.02636188
83MP0009672_abnormal_birth_weight1.02160071
84MP0009333_abnormal_splenocyte_physiolog1.01682683
85MP0010234_abnormal_vibrissa_follicle1.00862267
86MP0002210_abnormal_sex_determination1.00178588
87MP0003698_abnormal_male_reproductive1.00175641
88MP0002092_abnormal_eye_morphology0.99479322
89MP0002928_abnormal_bile_duct0.96689272
90MP0009703_decreased_birth_body0.96072722
91MP0010678_abnormal_skin_adnexa0.94227913
92MP0006035_abnormal_mitochondrial_morpho0.93968224
93MP0006054_spinal_hemorrhage0.92957878
94MP0001485_abnormal_pinna_reflex0.92249089
95MP0002233_abnormal_nose_morphology0.91460857
96MP0008995_early_reproductive_senescence0.91379662
97MP0002111_abnormal_tail_morphology0.91210530
98MP0002697_abnormal_eye_size0.90453756
99MP0002429_abnormal_blood_cell0.90353231
100MP0002837_dystrophic_cardiac_calcinosis0.87657338
101MP0003937_abnormal_limbs/digits/tail_de0.87068473
102MP0001929_abnormal_gametogenesis0.86921726
103MP0001849_ear_inflammation0.86705295
104MP0005379_endocrine/exocrine_gland_phen0.86670979
105MP0001800_abnormal_humoral_immune0.86358228
106MP0001145_abnormal_male_reproductive0.85073992
107MP0005646_abnormal_pituitary_gland0.84859104
108MP0009046_muscle_twitch0.84795385
109MP0005410_abnormal_fertilization0.84688796
110MP0005220_abnormal_exocrine_pancreas0.84455348
111MP0005499_abnormal_olfactory_system0.83222181
112MP0005394_taste/olfaction_phenotype0.83222181
113MP0003119_abnormal_digestive_system0.82740897
114MP0000716_abnormal_immune_system0.81942577
115MP0001324_abnormal_eye_pigmentation0.81360799
116MP0005075_abnormal_melanosome_morpholog0.81338224
117MP0005621_abnormal_cell_physiology0.80893935
118MP0003755_abnormal_palate_morphology0.80816891
119MP0005395_other_phenotype0.80290996
120MP0003718_maternal_effect0.78923808
121MP0001286_abnormal_eye_development0.78768370
122MP0003941_abnormal_skin_development0.78243273
123MP0000685_abnormal_immune_system0.77910969
124MP0005195_abnormal_posterior_eye0.77477337
125MP0005389_reproductive_system_phenotype0.77455260
126MP0005187_abnormal_penis_morphology0.76868559
127MP0005083_abnormal_biliary_tract0.76742177
128MP0002736_abnormal_nociception_after0.76675461
129MP0000428_abnormal_craniofacial_morphol0.76416116
130MP0001299_abnormal_eye_distance/0.74977333
131MP0003448_altered_tumor_morphology0.74756313
132MP0002925_abnormal_cardiovascular_devel0.74069308
133MP0005408_hypopigmentation0.73662621
134MP0000432_abnormal_head_morphology0.73606294
135MP0000778_abnormal_nervous_system0.73536545
136MP0002405_respiratory_system_inflammati0.73536107
137MP0002095_abnormal_skin_pigmentation0.73514376
138MP0001764_abnormal_homeostasis0.72910974
139MP0000653_abnormal_sex_gland0.72670409
140MP0001984_abnormal_olfaction0.72525382
141MP0005384_cellular_phenotype0.72463388
142MP0002452_abnormal_antigen_presenting0.72377950
143MP0003861_abnormal_nervous_system0.72367131
144MP0003115_abnormal_respiratory_system0.71835514
145MP0003806_abnormal_nucleotide_metabolis0.71750167
146MP0002877_abnormal_melanocyte_morpholog0.70642508
147MP0000477_abnormal_intestine_morphology0.70204014
148MP0003300_gastrointestinal_ulcer0.69568071
149MP0003453_abnormal_keratinocyte_physiol0.69349114
150MP0002420_abnormal_adaptive_immunity0.67685583
151MP0003943_abnormal_hepatobiliary_system0.67234358
152MP0003935_abnormal_craniofacial_develop0.66715724
153MP0001819_abnormal_immune_cell0.66611732
154MP0010155_abnormal_intestine_physiology0.66464065
155MP0001119_abnormal_female_reproductive0.66372047
156MP0003303_peritoneal_inflammation0.65294539
157MP0002282_abnormal_trachea_morphology0.65199841
158MP0000371_diluted_coat_color0.63777353

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)3.52943937
2Reticulocytopenia (HP:0001896)3.41196559
3Chromosomal breakage induced by crosslinking agents (HP:0003221)3.32525898
4Pancreatic cysts (HP:0001737)3.26289203
5Birth length less than 3rd percentile (HP:0003561)3.14159686
6Selective tooth agenesis (HP:0001592)2.99712694
7Pancreatic fibrosis (HP:0100732)2.98115788
8Abnormality of chromosome stability (HP:0003220)2.76937170
9Ependymoma (HP:0002888)2.74870750
10Colon cancer (HP:0003003)2.71063317
11Myelodysplasia (HP:0002863)2.68459138
12Medulloblastoma (HP:0002885)2.64415376
13Increased nuchal translucency (HP:0010880)2.63998601
14True hermaphroditism (HP:0010459)2.63144636
15Abnormality of cells of the erythroid lineage (HP:0012130)2.58848218
16Intestinal atresia (HP:0011100)2.58265853
17Abnormality of midbrain morphology (HP:0002418)2.56501967
18Molar tooth sign on MRI (HP:0002419)2.56501967
19Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.53313510
20Short 4th metacarpal (HP:0010044)2.53313510
21Meckel diverticulum (HP:0002245)2.52556325
22Ectopic kidney (HP:0000086)2.50272944
23Deviation of the thumb (HP:0009603)2.47416702
24Aplasia/Hypoplasia of the uvula (HP:0010293)2.46012967
25Squamous cell carcinoma (HP:0002860)2.45559892
26Abnormality of the ileum (HP:0001549)2.43790171
27Abnormal number of erythroid precursors (HP:0012131)2.41041212
28Impulsivity (HP:0100710)2.38889497
29Proximal placement of thumb (HP:0009623)2.38587517
30Abnormality of the preputium (HP:0100587)2.37650042
31Basal cell carcinoma (HP:0002671)2.37304028
32Patellar aplasia (HP:0006443)2.36125100
33Cutaneous melanoma (HP:0012056)2.35595706
34Nephronophthisis (HP:0000090)2.33802480
35Missing ribs (HP:0000921)2.32532011
3611 pairs of ribs (HP:0000878)2.31989311
37Amaurosis fugax (HP:0100576)2.28329882
38Aplastic anemia (HP:0001915)2.28211336
39Abnormality of the renal cortex (HP:0011035)2.27906134
40Abnormality of the pons (HP:0007361)2.26133457
41Duodenal stenosis (HP:0100867)2.25978833
42Small intestinal stenosis (HP:0012848)2.25978833
43Hypoplasia of the pons (HP:0012110)2.25793163
44Chronic hepatic failure (HP:0100626)2.25606805
45Heterotopia (HP:0002282)2.25499669
46Thrombocytosis (HP:0001894)2.24803198
47Increased density of long bones (HP:0006392)2.24000171
48Hyperacusis (HP:0010780)2.23847913
49High pitched voice (HP:0001620)2.23654634
50Abnormality of the anterior horn cell (HP:0006802)2.22759876
51Degeneration of anterior horn cells (HP:0002398)2.22759876
52Aplasia/Hypoplasia of the patella (HP:0006498)2.22274645
53Aplasia/Hypoplasia of the tibia (HP:0005772)2.20823367
54Rhabdomyosarcoma (HP:0002859)2.15211738
55Triphalangeal thumb (HP:0001199)2.14700750
56Pendular nystagmus (HP:0012043)2.14676754
57Nephroblastoma (Wilms tumor) (HP:0002667)2.14478756
58Abnormality of the carotid arteries (HP:0005344)2.13668561
59Absent thumb (HP:0009777)2.12681964
60Breast hypoplasia (HP:0003187)2.12504098
61Absent radius (HP:0003974)2.11427752
62Atresia of the external auditory canal (HP:0000413)2.11400597
63Embryonal renal neoplasm (HP:0011794)2.08721115
64Bifid tongue (HP:0010297)2.08509485
65Septo-optic dysplasia (HP:0100842)2.07991774
66Medial flaring of the eyebrow (HP:0010747)2.06323119
67Optic nerve hypoplasia (HP:0000609)2.05407846
68Abnormality of the labia minora (HP:0012880)2.04041761
69Methylmalonic acidemia (HP:0002912)2.03491715
70Abnormality of the renal medulla (HP:0100957)2.02869052
71Astrocytoma (HP:0009592)2.01564953
72Abnormality of the astrocytes (HP:0100707)2.01564953
73Bilateral microphthalmos (HP:0007633)2.01311354
74Aplasia/Hypoplasia of the tongue (HP:0010295)2.01026099
75Renal duplication (HP:0000075)2.00224061
76Prominent nose (HP:0000448)2.00017825
77Pallor (HP:0000980)1.99874666
78Sclerocornea (HP:0000647)1.97706000
79Tracheoesophageal fistula (HP:0002575)1.97428913
80Acute necrotizing encephalopathy (HP:0006965)1.97365293
81Short tibia (HP:0005736)1.94955263
82Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.94621076
83Hyperglycinemia (HP:0002154)1.94284349
84Absent forearm bone (HP:0003953)1.93841707
85Aplasia involving forearm bones (HP:0009822)1.93841707
86Oral leukoplakia (HP:0002745)1.93802585
87Cafe-au-lait spot (HP:0000957)1.93346144
88Duplicated collecting system (HP:0000081)1.93074527
89Volvulus (HP:0002580)1.93003005
90Neoplasm of the adrenal cortex (HP:0100641)1.92782597
91Acute myeloid leukemia (HP:0004808)1.91833437
92Renal cortical cysts (HP:0000803)1.91657577
93Sloping forehead (HP:0000340)1.90814931
94Acute encephalopathy (HP:0006846)1.90569561
95Carpal bone hypoplasia (HP:0001498)1.89538798
96Gastrointestinal atresia (HP:0002589)1.89441614
97Abnormality of the duodenum (HP:0002246)1.89071714
98Abnormality of the 4th metacarpal (HP:0010012)1.88911228
99Preaxial hand polydactyly (HP:0001177)1.88405881
100Abnormal lung lobation (HP:0002101)1.88347026
101Congenital stationary night blindness (HP:0007642)1.86934629
102Abnormal biliary tract physiology (HP:0012439)1.84262486
103Bile duct proliferation (HP:0001408)1.84262486
104Tubular atrophy (HP:0000092)1.83831726
105Pancreatic islet-cell hyperplasia (HP:0004510)1.83074332
106Neoplasm of the pancreas (HP:0002894)1.83012943
107Deep philtrum (HP:0002002)1.82818100
108Dandy-Walker malformation (HP:0001305)1.82214822
109Renovascular hypertension (HP:0100817)1.81640185
110Increased CSF lactate (HP:0002490)1.81542780
111Bone marrow hypocellularity (HP:0005528)1.81175004
112Horseshoe kidney (HP:0000085)1.81127599
113Anophthalmia (HP:0000528)1.80468008
114Agnosia (HP:0010524)1.80315024
115Type II lissencephaly (HP:0007260)1.79910000
116Skull defect (HP:0001362)1.79851742
117Abnormal number of incisors (HP:0011064)1.79405428
118Breech presentation (HP:0001623)1.78171945
119Neoplasm of the oral cavity (HP:0100649)1.77932263
120Astigmatism (HP:0000483)1.77101890
121Abnormality of the renal collecting system (HP:0004742)1.76763941
122Abnormality of the calcaneus (HP:0008364)1.76739511
123Genital tract atresia (HP:0001827)1.75676437
124Supernumerary spleens (HP:0009799)1.75639863
125Abnormality of reticulocytes (HP:0004312)1.74220757
126Progressive macrocephaly (HP:0004481)1.73721387
127Cystic liver disease (HP:0006706)1.73525088
128Cerebellar dysplasia (HP:0007033)1.73010155
129Skin tags (HP:0010609)1.72993513
130Progressive inability to walk (HP:0002505)1.72055308
131Anencephaly (HP:0002323)1.71612070
132Sandal gap (HP:0001852)1.71536032
133Personality changes (HP:0000751)1.71523201
134Oligodactyly (hands) (HP:0001180)1.71186306
135Long eyelashes (HP:0000527)1.71171750
136Neoplasm of striated muscle (HP:0009728)1.70147474
137Abnormality of the fingertips (HP:0001211)1.70015447
138Short thumb (HP:0009778)1.69898021
139Clubbing of toes (HP:0100760)1.69754050
140Preauricular skin tag (HP:0000384)1.69606224
141Vaginal atresia (HP:0000148)1.69590653
142Aplasia/hypoplasia of the humerus (HP:0006507)1.68327027
143Aplasia/Hypoplasia of the fovea (HP:0008060)1.68165230
144Hypoplasia of the fovea (HP:0007750)1.68165230
145Methylmalonic aciduria (HP:0012120)1.67895835
146Small hand (HP:0200055)1.67768675
147Lymphoma (HP:0002665)1.67572606
148Glioma (HP:0009733)1.66476622
149Abdominal situs inversus (HP:0003363)1.66412131
150Abnormality of abdominal situs (HP:0011620)1.66412131
151Abnormality of methionine metabolism (HP:0010901)1.66039424
152Increased hepatocellular lipid droplets (HP:0006565)1.65738134
153Pseudobulbar signs (HP:0002200)1.64212053
154IgM deficiency (HP:0002850)1.63601488
155Postaxial foot polydactyly (HP:0001830)1.63471861
156Oligohydramnios (HP:0001562)1.63090909
157Abnormality of alanine metabolism (HP:0010916)1.61709362
158Hyperalaninemia (HP:0003348)1.61709362
159Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.61709362
160Recurrent viral infections (HP:0004429)1.61368638
161Elfin facies (HP:0004428)1.60473341
162Cortical dysplasia (HP:0002539)1.60359178
163Bicuspid aortic valve (HP:0001647)1.60225733
164Overriding aorta (HP:0002623)1.59916493
165Cutis marmorata (HP:0000965)1.59441487
166Macrocytic anemia (HP:0001972)1.59343321
167Short humerus (HP:0005792)1.57279786

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.13759276
2WEE13.25091003
3EEF2K3.10811792
4FRK3.07966430
5NEK22.81028849
6BUB12.64557077
7CDK122.52756738
8PKN22.42961513
9EIF2AK12.42755822
10MAP3K102.41077433
11BMPR1B2.32500676
12NUAK12.23715956
13PBK2.07588033
14WNK32.07107049
15SRPK12.06923094
16RPS6KB22.05473674
17TNIK2.00700279
18TRIM281.97192548
19BRSK21.95677336
20RPS6KA41.94933811
21MKNK11.83608575
22TTK1.82070242
23NME11.81684671
24STK101.74294133
25PASK1.71259856
26MAP3K41.69666994
27TESK21.59936415
28MAP4K21.58787516
29VRK21.58553505
30PLK11.57958560
31SCYL21.56041519
32TGFBR11.54098570
33AURKB1.53402390
34CDK41.53255551
35ATR1.52647057
36MAP3K81.46737044
37CDK71.44413672
38PLK41.40862845
39BCR1.40707091
40EPHA21.40071048
41FLT31.35245741
42ACVR1B1.33791232
43TRIB31.32695702
44CASK1.31533775
45CDK61.30710502
46MAP2K31.30378559
47TAF11.28843063
48CHEK21.28775505
49DYRK31.28717691
50PLK31.27714829
51TLK11.26923254
52NEK11.26331859
53CHEK11.23055433
54MKNK21.21686299
55ERBB31.20074788
56TESK11.19837258
57LRRK21.18332347
58MAP4K11.18039448
59NME21.17611572
60PIM11.15259042
61TSSK61.13279765
62STK38L1.12891695
63STK41.11557494
64STK391.10105295
65ALK1.09678565
66BRD41.07828179
67PAK41.07668445
68STK161.04779913
69STK31.04197117
70VRK11.03218293
71LATS11.02366802
72PLK21.01115333
73CSNK1G10.97734118
74GRK10.96012072
75MAP2K70.95413710
76ATM0.95149449
77ADRBK20.95000060
78BRSK10.94138824
79PINK10.92213495
80WNK40.90300574
81EIF2AK30.89921027
82OXSR10.88181681
83INSRR0.87872087
84MTOR0.87054177
85CSNK1G30.86414310
86CDK20.83719882
87AURKA0.80822030
88PTK60.80137224
89CSNK1G20.79814635
90CSNK1A1L0.75711517
91FGFR20.73664461
92BTK0.71342015
93TTN0.68968050
94DYRK20.68323186
95EIF2AK20.65022448
96MELK0.61532087
97PAK20.60259625
98MARK30.59533918
99CDK10.58701908
100JAK30.56715338
101PRKCG0.55559007
102PRKCE0.54455849
103CCNB10.53666626
104PNCK0.50535874
105CSF1R0.49723098
106CLK10.48539514
107BCKDK0.48265050
108CHUK0.47827769
109FGFR10.47739020
110ZAK0.46398174
111GRK60.46079715
112RPS6KA50.45792368
113PAK10.45701646
114ICK0.44712804
115ZAP700.44521677
116ERBB40.43152269
117CSNK2A20.42536057
118MAPK130.42098836
119PRKCI0.40947048
120CAMK1G0.40265725
121BMX0.40040961
122CSNK1E0.39630128
123DYRK1B0.39245236
124AKT20.37369327
125CDK80.36201323
126TRPM70.35732595
127CDK30.35413394
128TYK20.34914798
129CSNK1D0.33996194
130KDR0.33799853
131MAP3K30.33696578
132EPHA40.33618033
133AKT10.33049629
134CSNK2A10.33014626
135MAPKAPK20.32805140
136MAPK140.32541159
137PRKDC0.32163318
138PDGFRA0.30761960
139MAP3K90.29358514
140IRAK40.28064012
141CSNK1A10.27731827
142MAPK10.27481817
143MET0.26769192
144LATS20.26465374
145MST40.26285558
146PAK30.25809905
147YES10.25492939
148MAP3K140.25489545

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.38718629
2Mismatch repair_Homo sapiens_hsa034303.54075932
3One carbon pool by folate_Homo sapiens_hsa006703.00957260
4RNA transport_Homo sapiens_hsa030132.93682256
5Spliceosome_Homo sapiens_hsa030402.89699975
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.86620473
7Base excision repair_Homo sapiens_hsa034102.84427764
8Cell cycle_Homo sapiens_hsa041102.76166452
9Protein export_Homo sapiens_hsa030602.49303183
10Homologous recombination_Homo sapiens_hsa034402.48593873
11Nucleotide excision repair_Homo sapiens_hsa034202.48347957
12Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.42002229
13Ribosome_Homo sapiens_hsa030102.16052886
14Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.13322664
15Fanconi anemia pathway_Homo sapiens_hsa034601.98659502
16mRNA surveillance pathway_Homo sapiens_hsa030151.95965579
17Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.86662346
18Non-homologous end-joining_Homo sapiens_hsa034501.84584972
19p53 signaling pathway_Homo sapiens_hsa041151.75097573
20Propanoate metabolism_Homo sapiens_hsa006401.74549556
21Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.74074132
22RNA degradation_Homo sapiens_hsa030181.71818331
23Systemic lupus erythematosus_Homo sapiens_hsa053221.68240432
24Pyrimidine metabolism_Homo sapiens_hsa002401.65339075
25Basal transcription factors_Homo sapiens_hsa030221.62984653
26RNA polymerase_Homo sapiens_hsa030201.55778397
27Oxidative phosphorylation_Homo sapiens_hsa001901.49286603
28Butanoate metabolism_Homo sapiens_hsa006501.44524361
29Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.43821028
30Viral carcinogenesis_Homo sapiens_hsa052031.41074642
31Steroid biosynthesis_Homo sapiens_hsa001001.38278226
32Proteasome_Homo sapiens_hsa030501.35390386
33Herpes simplex infection_Homo sapiens_hsa051681.34018674
34Phototransduction_Homo sapiens_hsa047441.32437202
35Vitamin B6 metabolism_Homo sapiens_hsa007501.28810152
36Parkinsons disease_Homo sapiens_hsa050121.28635286
37Epstein-Barr virus infection_Homo sapiens_hsa051691.26417133
38Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.25096454
39Small cell lung cancer_Homo sapiens_hsa052221.24659991
40Selenocompound metabolism_Homo sapiens_hsa004501.22501395
41Huntingtons disease_Homo sapiens_hsa050161.22068502
42Chronic myeloid leukemia_Homo sapiens_hsa052201.19725490
43MicroRNAs in cancer_Homo sapiens_hsa052061.17635486
44Antigen processing and presentation_Homo sapiens_hsa046121.15221195
45HTLV-I infection_Homo sapiens_hsa051661.12410463
46Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.07987964
47Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.00386258
48Caffeine metabolism_Homo sapiens_hsa002320.99653505
49Transcriptional misregulation in cancer_Homo sapiens_hsa052020.96732211
50Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.96583656
51Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.95618831
52NF-kappa B signaling pathway_Homo sapiens_hsa040640.94790383
53Thyroid cancer_Homo sapiens_hsa052160.94471289
54Legionellosis_Homo sapiens_hsa051340.94294669
55Pyruvate metabolism_Homo sapiens_hsa006200.93890993
56Nitrogen metabolism_Homo sapiens_hsa009100.92698827
57Shigellosis_Homo sapiens_hsa051310.91121028
58Measles_Homo sapiens_hsa051620.91079531
59Tryptophan metabolism_Homo sapiens_hsa003800.90877569
60Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.90100427
61Apoptosis_Homo sapiens_hsa042100.89821439
62Maturity onset diabetes of the young_Homo sapiens_hsa049500.86686605
63Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.85380318
64Oocyte meiosis_Homo sapiens_hsa041140.83167490
65Fatty acid elongation_Homo sapiens_hsa000620.81733029
66Bladder cancer_Homo sapiens_hsa052190.79362086
67Primary immunodeficiency_Homo sapiens_hsa053400.79184281
68Leishmaniasis_Homo sapiens_hsa051400.78993446
69Colorectal cancer_Homo sapiens_hsa052100.78616587
70Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.78244694
71Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.77523719
72Notch signaling pathway_Homo sapiens_hsa043300.76190891
73Hepatitis B_Homo sapiens_hsa051610.76119567
74Adherens junction_Homo sapiens_hsa045200.75816813
75Viral myocarditis_Homo sapiens_hsa054160.75063367
76Cyanoamino acid metabolism_Homo sapiens_hsa004600.75014909
77Biosynthesis of amino acids_Homo sapiens_hsa012300.74149249
78Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.73093824
79Pentose phosphate pathway_Homo sapiens_hsa000300.72124711
80Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.71952759
81Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.71932813
82Acute myeloid leukemia_Homo sapiens_hsa052210.71740281
83TGF-beta signaling pathway_Homo sapiens_hsa043500.70245692
84Pancreatic cancer_Homo sapiens_hsa052120.69931099
85Peroxisome_Homo sapiens_hsa041460.69884614
86Alzheimers disease_Homo sapiens_hsa050100.69720468
87Basal cell carcinoma_Homo sapiens_hsa052170.69623369
88Metabolic pathways_Homo sapiens_hsa011000.68454438
89Hippo signaling pathway_Homo sapiens_hsa043900.68055871
90Central carbon metabolism in cancer_Homo sapiens_hsa052300.67825516
91B cell receptor signaling pathway_Homo sapiens_hsa046620.66992707
92Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.66323511
93Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.63163417
94Purine metabolism_Homo sapiens_hsa002300.62817976
95Drug metabolism - other enzymes_Homo sapiens_hsa009830.61693378
96Cysteine and methionine metabolism_Homo sapiens_hsa002700.61044624
97Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.60808757
98NOD-like receptor signaling pathway_Homo sapiens_hsa046210.60787208
99Nicotine addiction_Homo sapiens_hsa050330.59592937
100Olfactory transduction_Homo sapiens_hsa047400.59359847
101Non-small cell lung cancer_Homo sapiens_hsa052230.59121339
102Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.58399095
103Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.58324715
104Fatty acid metabolism_Homo sapiens_hsa012120.57782440
105Proteoglycans in cancer_Homo sapiens_hsa052050.57254331
106Lysine degradation_Homo sapiens_hsa003100.57182394
107Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.57137964
108Influenza A_Homo sapiens_hsa051640.56410893
109Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.55485718
110N-Glycan biosynthesis_Homo sapiens_hsa005100.55429231
111Prostate cancer_Homo sapiens_hsa052150.55256503
112Alcoholism_Homo sapiens_hsa050340.54964565
113Leukocyte transendothelial migration_Homo sapiens_hsa046700.53927281
114T cell receptor signaling pathway_Homo sapiens_hsa046600.52607464
115Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.51793020
116Toxoplasmosis_Homo sapiens_hsa051450.51332285
117beta-Alanine metabolism_Homo sapiens_hsa004100.50535082
118Regulation of autophagy_Homo sapiens_hsa041400.50028564
119Taste transduction_Homo sapiens_hsa047420.49966769
120Linoleic acid metabolism_Homo sapiens_hsa005910.49692160
121Steroid hormone biosynthesis_Homo sapiens_hsa001400.49619387
122Primary bile acid biosynthesis_Homo sapiens_hsa001200.49298813
123Pathways in cancer_Homo sapiens_hsa052000.48567569
124RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.48364544
125Glutathione metabolism_Homo sapiens_hsa004800.48330715
126Cardiac muscle contraction_Homo sapiens_hsa042600.47863560
127mTOR signaling pathway_Homo sapiens_hsa041500.47572751
128Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.47513698
129Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.45300032
130Retinol metabolism_Homo sapiens_hsa008300.42486504
131HIF-1 signaling pathway_Homo sapiens_hsa040660.42252577
132Ether lipid metabolism_Homo sapiens_hsa005650.41782752
133AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.41637684
134Hematopoietic cell lineage_Homo sapiens_hsa046400.41455919
135Sulfur metabolism_Homo sapiens_hsa009200.41365177
136Endometrial cancer_Homo sapiens_hsa052130.40535014
137TNF signaling pathway_Homo sapiens_hsa046680.40243905
138Pentose and glucuronate interconversions_Homo sapiens_hsa000400.38599695
139Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.38211209
140Jak-STAT signaling pathway_Homo sapiens_hsa046300.37040639
141Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.36835239
142Sulfur relay system_Homo sapiens_hsa041220.36599557
143Folate biosynthesis_Homo sapiens_hsa007900.36584880
144Circadian rhythm_Homo sapiens_hsa047100.36152864
145Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.35854509
146Osteoclast differentiation_Homo sapiens_hsa043800.35488275
147Wnt signaling pathway_Homo sapiens_hsa043100.35204441
148Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.33790322
149Intestinal immune network for IgA production_Homo sapiens_hsa046720.33470815
150FoxO signaling pathway_Homo sapiens_hsa040680.32798164
151Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.31732193
152Focal adhesion_Homo sapiens_hsa045100.31478205
153Arginine and proline metabolism_Homo sapiens_hsa003300.30265364
154Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.30245817
155Carbon metabolism_Homo sapiens_hsa012000.29958612
1562-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.29958108
157alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.29463286
158Hedgehog signaling pathway_Homo sapiens_hsa043400.29461670
159Toll-like receptor signaling pathway_Homo sapiens_hsa046200.28177315
160Fatty acid degradation_Homo sapiens_hsa000710.27897781
161Fatty acid biosynthesis_Homo sapiens_hsa000610.27662190

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