Rank | Gene Set | Z-score |
---|---|---|
1 | proteasome assembly (GO:0043248) | 5.45811796 |
2 | nuclear pore complex assembly (GO:0051292) | 5.37928087 |
3 | nuclear pore organization (GO:0006999) | 5.31078921 |
4 | protein localization to kinetochore (GO:0034501) | 4.52620338 |
5 | mitotic nuclear envelope disassembly (GO:0007077) | 4.48763282 |
6 | ribosome assembly (GO:0042255) | 4.39859245 |
7 | nucleobase biosynthetic process (GO:0046112) | 4.38363900 |
8 | mitotic metaphase plate congression (GO:0007080) | 4.33869450 |
9 | folic acid-containing compound biosynthetic process (GO:0009396) | 4.30836339 |
10 | purine nucleobase biosynthetic process (GO:0009113) | 4.29290730 |
11 | DNA unwinding involved in DNA replication (GO:0006268) | 4.28402478 |
12 | formation of translation preinitiation complex (GO:0001731) | 4.26230271 |
13 | nuclear envelope disassembly (GO:0051081) | 4.25314276 |
14 | membrane disassembly (GO:0030397) | 4.25314276 |
15 | DNA replication-dependent nucleosome organization (GO:0034723) | 4.19061433 |
16 | DNA replication-dependent nucleosome assembly (GO:0006335) | 4.19061433 |
17 | pore complex assembly (GO:0046931) | 4.18782842 |
18 | DNA replication initiation (GO:0006270) | 4.14151901 |
19 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 4.13530240 |
20 | protein localization to chromosome, centromeric region (GO:0071459) | 4.04400419 |
21 | non-recombinational repair (GO:0000726) | 3.94783325 |
22 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.94783325 |
23 | regulation of spindle organization (GO:0090224) | 3.94301388 |
24 | establishment of integrated proviral latency (GO:0075713) | 3.94201600 |
25 | transcription from mitochondrial promoter (GO:0006390) | 3.85780423 |
26 | DNA replication checkpoint (GO:0000076) | 3.84397371 |
27 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.83200993 |
28 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.83154956 |
29 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.79057632 |
30 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.76222326 |
31 | IMP biosynthetic process (GO:0006188) | 3.75699395 |
32 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.73659147 |
33 | mitotic chromosome condensation (GO:0007076) | 3.69950007 |
34 | positive regulation of chromosome segregation (GO:0051984) | 3.68250857 |
35 | maturation of SSU-rRNA (GO:0030490) | 3.66415190 |
36 | metaphase plate congression (GO:0051310) | 3.64336452 |
37 | ribosome biogenesis (GO:0042254) | 3.64029865 |
38 | regulation of translational termination (GO:0006449) | 3.63273766 |
39 | DNA strand elongation (GO:0022616) | 3.56283384 |
40 | regulation of mitotic spindle organization (GO:0060236) | 3.54461960 |
41 | tRNA aminoacylation (GO:0043039) | 3.53147184 |
42 | amino acid activation (GO:0043038) | 3.53147184 |
43 | folic acid metabolic process (GO:0046655) | 3.52693824 |
44 | tRNA aminoacylation for protein translation (GO:0006418) | 3.51673755 |
45 | mitochondrial RNA metabolic process (GO:0000959) | 3.49766682 |
46 | cullin deneddylation (GO:0010388) | 3.49031154 |
47 | protein heterotetramerization (GO:0051290) | 3.48572660 |
48 | chaperone-mediated protein complex assembly (GO:0051131) | 3.48542452 |
49 | chromatin remodeling at centromere (GO:0031055) | 3.47720024 |
50 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.47139189 |
51 | nuclear envelope organization (GO:0006998) | 3.43503634 |
52 | regulation of centrosome cycle (GO:0046605) | 3.40470606 |
53 | IMP metabolic process (GO:0046040) | 3.38543711 |
54 | mitotic sister chromatid segregation (GO:0000070) | 3.37910619 |
55 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.37276353 |
56 | negative regulation of ligase activity (GO:0051352) | 3.37276353 |
57 | regulation of histone H3-K9 methylation (GO:0051570) | 3.35835900 |
58 | protein deneddylation (GO:0000338) | 3.34835392 |
59 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.34332474 |
60 | CENP-A containing nucleosome assembly (GO:0034080) | 3.32087752 |
61 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.31337967 |
62 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.31337967 |
63 | isotype switching (GO:0045190) | 3.31337967 |
64 | establishment of viral latency (GO:0019043) | 3.30200535 |
65 | sister chromatid segregation (GO:0000819) | 3.29768462 |
66 | DNA double-strand break processing (GO:0000729) | 3.29086464 |
67 | regulation of chromosome segregation (GO:0051983) | 3.24996273 |
68 | histone exchange (GO:0043486) | 3.24159729 |
69 | ribonucleoprotein complex disassembly (GO:0032988) | 3.24139861 |
70 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.24069725 |
71 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.23855969 |
72 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.23419067 |
73 | establishment of chromosome localization (GO:0051303) | 3.22814272 |
74 | DNA geometric change (GO:0032392) | 3.22673401 |
75 | DNA duplex unwinding (GO:0032508) | 3.22349864 |
76 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.22318357 |
77 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.22318357 |
78 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.20503249 |
79 | positive regulation of ligase activity (GO:0051351) | 3.19868012 |
80 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.18838274 |
81 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.18838274 |
82 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.18838274 |
83 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.18408857 |
84 | kinetochore organization (GO:0051383) | 3.16361001 |
85 | heterochromatin organization (GO:0070828) | 3.16247628 |
86 | DNA replication-independent nucleosome organization (GO:0034724) | 3.16162802 |
87 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.16162802 |
88 | tRNA methylation (GO:0030488) | 3.15001411 |
89 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.14636909 |
90 | mitotic sister chromatid cohesion (GO:0007064) | 3.11394104 |
91 | regulation of centriole replication (GO:0046599) | 3.11262446 |
92 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.10430861 |
93 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.10430861 |
94 | response to X-ray (GO:0010165) | 3.08781890 |
95 | spindle checkpoint (GO:0031577) | 3.07689084 |
96 | telomere maintenance via recombination (GO:0000722) | 3.06148030 |
97 | COPII vesicle coating (GO:0048208) | 3.04818716 |
98 | mitotic recombination (GO:0006312) | 3.04717373 |
99 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.03677336 |
100 | negative regulation of histone methylation (GO:0031061) | 3.03386787 |
101 | regulation of translation in response to stress (GO:0043555) | 3.00649042 |
102 | synaptonemal complex assembly (GO:0007130) | 3.00643949 |
103 | protein K6-linked ubiquitination (GO:0085020) | 2.99903298 |
104 | regulation of RNA export from nucleus (GO:0046831) | 2.98122899 |
105 | negative regulation of chromosome segregation (GO:0051985) | 2.97855709 |
106 | regulation of sister chromatid cohesion (GO:0007063) | 2.97315534 |
107 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.96433027 |
108 | ribosomal large subunit biogenesis (GO:0042273) | 2.95771796 |
109 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 2.95057689 |
110 | protein localization to chromosome (GO:0034502) | 2.94026091 |
111 | mitotic spindle checkpoint (GO:0071174) | 2.94011495 |
112 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 2.93578892 |
113 | negative regulation of sister chromatid segregation (GO:0033046) | 2.93578892 |
114 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 2.93578892 |
115 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 2.93578892 |
116 | chromatin assembly or disassembly (GO:0006333) | 2.92975108 |
117 | regulation of mitotic sister chromatid separation (GO:0010965) | 2.91664161 |
118 | regulation of sister chromatid segregation (GO:0033045) | 2.91664161 |
119 | DNA ligation (GO:0006266) | 2.90556323 |
120 | meiotic chromosome segregation (GO:0045132) | 2.89532379 |
121 | piRNA metabolic process (GO:0034587) | 2.89411152 |
122 | rRNA processing (GO:0006364) | 2.89221811 |
123 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 2.88890537 |
124 | spindle assembly checkpoint (GO:0071173) | 2.88798776 |
125 | regulation of posttranscriptional gene silencing (GO:0060147) | 2.88336085 |
126 | regulation of gene silencing by miRNA (GO:0060964) | 2.88336085 |
127 | regulation of gene silencing by RNA (GO:0060966) | 2.88336085 |
128 | mitotic spindle assembly checkpoint (GO:0007094) | 2.85982828 |
129 | regulation of ligase activity (GO:0051340) | 2.85902477 |
130 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 2.85641365 |
131 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.84898618 |
132 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.84898618 |
133 | chromosome condensation (GO:0030261) | 2.84398136 |
134 | lipopolysaccharide biosynthetic process (GO:0009103) | 2.84006011 |
135 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 2.82888307 |
136 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 2.82888307 |
137 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 2.82888307 |
138 | G1/S transition of mitotic cell cycle (GO:0000082) | 2.82872148 |
139 | cell cycle G1/S phase transition (GO:0044843) | 2.82872148 |
140 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.82860240 |
141 | chromosome segregation (GO:0007059) | 2.82738765 |
142 | rRNA metabolic process (GO:0016072) | 2.82589775 |
143 | chromatin assembly (GO:0031497) | 2.82572290 |
144 | mitotic G1 DNA damage checkpoint (GO:0031571) | 2.82007341 |
145 | spliceosomal snRNP assembly (GO:0000387) | 2.81944194 |
146 | resolution of meiotic recombination intermediates (GO:0000712) | 2.81832547 |
147 | nucleobase-containing small molecule interconversion (GO:0015949) | 2.81334280 |
148 | DNA conformation change (GO:0071103) | 2.80693667 |
149 | maturation of 5.8S rRNA (GO:0000460) | 2.78914338 |
150 | histone-serine phosphorylation (GO:0035404) | 2.77502947 |
151 | synaptonemal complex organization (GO:0070193) | 2.76934593 |
152 | organelle disassembly (GO:1903008) | 2.74496443 |
153 | rRNA methylation (GO:0031167) | 2.74344091 |
154 | regulation of mitotic sister chromatid segregation (GO:0033047) | 2.73695765 |
155 | replication fork processing (GO:0031297) | 2.72953417 |
156 | mitochondrial DNA replication (GO:0006264) | 2.70496929 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 8.22272306 |
2 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.13338124 |
3 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.01949053 |
4 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.42680595 |
5 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.28557008 |
6 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 3.24069977 |
7 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.92020561 |
8 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.88639672 |
9 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.68106747 |
10 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.55159435 |
11 | * CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.51037051 |
12 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.49986282 |
13 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.47280064 |
14 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.39438922 |
15 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.39100195 |
16 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.38642187 |
17 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.38046956 |
18 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.34731803 |
19 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.23919317 |
20 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.16636327 |
21 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.10365141 |
22 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.07691507 |
23 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 2.05013645 |
24 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.01715651 |
25 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.99138282 |
26 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.93499197 |
27 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.88830310 |
28 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.88021446 |
29 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.84343592 |
30 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.80796558 |
31 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.79437694 |
32 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.75649665 |
33 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.74434814 |
34 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.74135220 |
35 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.73898953 |
36 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.73669336 |
37 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.73470231 |
38 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.72064644 |
39 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.72011121 |
40 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.69479984 |
41 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.64166806 |
42 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.63865916 |
43 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.63131992 |
44 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.61508435 |
45 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.61411798 |
46 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.56879109 |
47 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.56352454 |
48 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.50362990 |
49 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.48080731 |
50 | * KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.44286672 |
51 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.38340553 |
52 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.38297785 |
53 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.37274440 |
54 | MYC_22102868_ChIP-Seq_BL_Human | 1.36441922 |
55 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.35992663 |
56 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.35132007 |
57 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.32614275 |
58 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.31661946 |
59 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.28446373 |
60 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.28362052 |
61 | FUS_26573619_Chip-Seq_HEK293_Human | 1.28316362 |
62 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.26913325 |
63 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.25852841 |
64 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.25260226 |
65 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.25218507 |
66 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.24079128 |
67 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.24036904 |
68 | * FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.22440236 |
69 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.22313974 |
70 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.22073637 |
71 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.20721281 |
72 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.20721281 |
73 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.20721281 |
74 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.19024834 |
75 | GATA1_22025678_ChIP-Seq_K562_Human | 1.18448494 |
76 | EWS_26573619_Chip-Seq_HEK293_Human | 1.16985515 |
77 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.16846524 |
78 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.14870021 |
79 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.14468641 |
80 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.12780526 |
81 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.12437326 |
82 | * DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.11481573 |
83 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.11365711 |
84 | * E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.10853680 |
85 | ELF5_23300383_ChIP-Seq_T47D_Human | 1.10659376 |
86 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.10398805 |
87 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.10223323 |
88 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.09190976 |
89 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.08168873 |
90 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.07240169 |
91 | * SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.06749532 |
92 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.06131228 |
93 | * CIITA_25753668_ChIP-Seq_RAJI_Human | 1.04423161 |
94 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 1.04216535 |
95 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.04141388 |
96 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.03385016 |
97 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.02452414 |
98 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.02193657 |
99 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.01498398 |
100 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.01124876 |
101 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.00789513 |
102 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.99228644 |
103 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.96510154 |
104 | ZNF274_21170338_ChIP-Seq_K562_Hela | 0.94403273 |
105 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 0.94239842 |
106 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.94087583 |
107 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.93409855 |
108 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.89644170 |
109 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.89243910 |
110 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.88811675 |
111 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.86810092 |
112 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.86740865 |
113 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.86609760 |
114 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.86266812 |
115 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 0.86086902 |
116 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.85998564 |
117 | * TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.85947410 |
118 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.85298091 |
119 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.83664340 |
120 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.83655400 |
121 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.83655400 |
122 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.83626712 |
123 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.83411077 |
124 | * BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.83182786 |
125 | * SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 0.82547914 |
126 | * SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 0.82547914 |
127 | * ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 0.82518581 |
128 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.81755179 |
129 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.81639048 |
130 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.81633273 |
131 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 0.81616092 |
132 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 0.80917470 |
133 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.80783605 |
134 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.79717746 |
135 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.79257829 |
136 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.78063172 |
137 | CHD1_26751641_Chip-Seq_LNCaP_Human | 0.77992281 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 5.07773725 |
2 | MP0003111_abnormal_nucleus_morphology | 4.18649896 |
3 | MP0004957_abnormal_blastocyst_morpholog | 4.16870561 |
4 | MP0010094_abnormal_chromosome_stability | 4.06506891 |
5 | MP0008057_abnormal_DNA_replication | 3.95545041 |
6 | MP0003077_abnormal_cell_cycle | 3.55368149 |
7 | MP0010352_gastrointestinal_tract_polyps | 3.17151626 |
8 | MP0000015_abnormal_ear_pigmentation | 2.92489446 |
9 | MP0010307_abnormal_tumor_latency | 2.77088206 |
10 | MP0000569_abnormal_digit_pigmentation | 2.74395332 |
11 | MP0005075_abnormal_melanosome_morpholog | 2.57410407 |
12 | MP0001730_embryonic_growth_arrest | 2.55870021 |
13 | MP0003806_abnormal_nucleotide_metabolis | 2.55270129 |
14 | MP0008058_abnormal_DNA_repair | 2.54251229 |
15 | MP0008007_abnormal_cellular_replicative | 2.41953182 |
16 | MP0009697_abnormal_copulation | 2.40280150 |
17 | MP0000350_abnormal_cell_proliferation | 2.20939053 |
18 | MP0008932_abnormal_embryonic_tissue | 2.14716758 |
19 | MP0003705_abnormal_hypodermis_morpholog | 2.09333937 |
20 | MP0002095_abnormal_skin_pigmentation | 2.09190216 |
21 | MP0003786_premature_aging | 1.87305324 |
22 | MP0008877_abnormal_DNA_methylation | 1.85435837 |
23 | MP0003123_paternal_imprinting | 1.82462234 |
24 | MP0001672_abnormal_embryogenesis/_devel | 1.78623517 |
25 | MP0005380_embryogenesis_phenotype | 1.78623517 |
26 | MP0003718_maternal_effect | 1.76941487 |
27 | MP0001697_abnormal_embryo_size | 1.74286239 |
28 | MP0008260_abnormal_autophagy | 1.73511778 |
29 | MP0004197_abnormal_fetal_growth/weight/ | 1.65315385 |
30 | MP0002090_abnormal_vision | 1.65218115 |
31 | MP0005174_abnormal_tail_pigmentation | 1.65107217 |
32 | MP0006036_abnormal_mitochondrial_physio | 1.62607199 |
33 | MP0002210_abnormal_sex_determination | 1.61059517 |
34 | MP0002080_prenatal_lethality | 1.60748567 |
35 | MP0003656_abnormal_erythrocyte_physiolo | 1.60069241 |
36 | MP0006035_abnormal_mitochondrial_morpho | 1.59437561 |
37 | MP0003984_embryonic_growth_retardation | 1.59268933 |
38 | MP0002088_abnormal_embryonic_growth/wei | 1.55774641 |
39 | MP0004233_abnormal_muscle_weight | 1.55643939 |
40 | MP0002086_abnormal_extraembryonic_tissu | 1.53967015 |
41 | MP0001929_abnormal_gametogenesis | 1.53174207 |
42 | MP0005408_hypopigmentation | 1.52850021 |
43 | MP0003941_abnormal_skin_development | 1.50535966 |
44 | MP0005076_abnormal_cell_differentiation | 1.47186124 |
45 | MP0002084_abnormal_developmental_patter | 1.44948229 |
46 | MP0002085_abnormal_embryonic_tissue | 1.43754335 |
47 | MP0001145_abnormal_male_reproductive | 1.42233704 |
48 | MP0002102_abnormal_ear_morphology | 1.39187252 |
49 | MP0002396_abnormal_hematopoietic_system | 1.37125423 |
50 | MP0000490_abnormal_crypts_of | 1.35686119 |
51 | MP0002877_abnormal_melanocyte_morpholog | 1.30908575 |
52 | MP0005275_abnormal_skin_tensile | 1.30080683 |
53 | MP0000371_diluted_coat_color | 1.27977638 |
54 | MP0002019_abnormal_tumor_incidence | 1.27754734 |
55 | MP0004808_abnormal_hematopoietic_stem | 1.27662000 |
56 | MP0000313_abnormal_cell_death | 1.26160953 |
57 | MP0004272_abnormal_basement_membrane | 1.22142681 |
58 | MP0005410_abnormal_fertilization | 1.22120474 |
59 | MP0000653_abnormal_sex_gland | 1.21522407 |
60 | MP0002060_abnormal_skin_morphology | 1.19498038 |
61 | MP0000358_abnormal_cell_content/ | 1.19000804 |
62 | MP0000749_muscle_degeneration | 1.16909355 |
63 | MP0003566_abnormal_cell_adhesion | 1.15983456 |
64 | MP0005023_abnormal_wound_healing | 1.11031123 |
65 | MP0001542_abnormal_bone_strength | 1.10671948 |
66 | MP0003567_abnormal_fetal_cardiomyocyte | 1.08670353 |
67 | MP0003186_abnormal_redox_activity | 1.07911287 |
68 | MP0000427_abnormal_hair_cycle | 1.06493616 |
69 | MP0009840_abnormal_foam_cell | 1.05656543 |
70 | MP0000372_irregular_coat_pigmentation | 1.05518037 |
71 | MP0010234_abnormal_vibrissa_follicle | 1.04757353 |
72 | MP0009333_abnormal_splenocyte_physiolog | 1.01117850 |
73 | MP0001324_abnormal_eye_pigmentation | 0.99994991 |
74 | MP0005197_abnormal_uvea_morphology | 0.98942274 |
75 | MP0001243_abnormal_dermal_layer | 0.98226624 |
76 | MP0005397_hematopoietic_system_phenotyp | 0.97104763 |
77 | MP0001545_abnormal_hematopoietic_system | 0.97104763 |
78 | MP0005501_abnormal_skin_physiology | 0.95760359 |
79 | MP0005621_abnormal_cell_physiology | 0.95626963 |
80 | MP0005165_increased_susceptibility_to | 0.94789861 |
81 | MP0001853_heart_inflammation | 0.94239342 |
82 | MP0003698_abnormal_male_reproductive | 0.94034772 |
83 | MP0001293_anophthalmia | 0.93258913 |
84 | MP0000647_abnormal_sebaceous_gland | 0.92874980 |
85 | MP0004264_abnormal_extraembryonic_tissu | 0.92828334 |
86 | MP0005384_cellular_phenotype | 0.92742583 |
87 | MP0000733_abnormal_muscle_development | 0.90444080 |
88 | MP0002269_muscular_atrophy | 0.90419240 |
89 | MP0003890_abnormal_embryonic-extraembry | 0.90194150 |
90 | MP0003221_abnormal_cardiomyocyte_apopto | 0.88734563 |
91 | MP0009672_abnormal_birth_weight | 0.86005039 |
92 | MP0001915_intracranial_hemorrhage | 0.85301181 |
93 | MP0009703_decreased_birth_body | 0.83489685 |
94 | MP0001661_extended_life_span | 0.82617742 |
95 | MP0001191_abnormal_skin_condition | 0.82443133 |
96 | MP0002653_abnormal_ependyma_morphology | 0.82154308 |
97 | MP0008438_abnormal_cutaneous_collagen | 0.81882350 |
98 | MP0004185_abnormal_adipocyte_glucose | 0.81025545 |
99 | MP0002161_abnormal_fertility/fecundity | 0.80078347 |
100 | MP0003878_abnormal_ear_physiology | 0.79141624 |
101 | MP0005377_hearing/vestibular/ear_phenot | 0.79141624 |
102 | MP0002075_abnormal_coat/hair_pigmentati | 0.78693048 |
103 | MP0001764_abnormal_homeostasis | 0.78116952 |
104 | MP0003136_yellow_coat_color | 0.77875914 |
105 | MP0005171_absent_coat_pigmentation | 0.77207446 |
106 | MP0004215_abnormal_myocardial_fiber | 0.76967223 |
107 | MP0000343_altered_response_to | 0.76420758 |
108 | MP0005389_reproductive_system_phenotype | 0.75806284 |
109 | MP0000689_abnormal_spleen_morphology | 0.74870730 |
110 | MP0003191_abnormal_cellular_cholesterol | 0.73942422 |
111 | MP0002722_abnormal_immune_system | 0.73376111 |
112 | MP0010386_abnormal_urinary_bladder | 0.73326843 |
113 | MP0002092_abnormal_eye_morphology | 0.72360278 |
114 | MP0002160_abnormal_reproductive_system | 0.71792572 |
115 | MP0003315_abnormal_perineum_morphology | 0.71523252 |
116 | MP0005395_other_phenotype | 0.70608231 |
117 | MP0000858_altered_metastatic_potential | 0.69954757 |
118 | MP0000703_abnormal_thymus_morphology | 0.69118294 |
119 | MP0000598_abnormal_liver_morphology | 0.68853578 |
120 | MP0003448_altered_tumor_morphology | 0.68235482 |
121 | MP0005367_renal/urinary_system_phenotyp | 0.67134497 |
122 | MP0000516_abnormal_urinary_system | 0.67134497 |
123 | MP0002332_abnormal_exercise_endurance | 0.67017303 |
124 | MP0000537_abnormal_urethra_morphology | 0.66793214 |
125 | MP0001849_ear_inflammation | 0.65830252 |
126 | MP0000627_abnormal_mammary_gland | 0.65518794 |
127 | MP0005253_abnormal_eye_physiology | 0.65418544 |
128 | MP0005257_abnormal_intraocular_pressure | 0.65144928 |
129 | MP0002398_abnormal_bone_marrow | 0.64385631 |
130 | MP0001216_abnormal_epidermal_layer | 0.64067474 |
131 | MP0003950_abnormal_plasma_membrane | 0.63943904 |
132 | MP0005266_abnormal_metabolism | 0.63698189 |
133 | MP0010678_abnormal_skin_adnexa | 0.63158275 |
134 | MP0002177_abnormal_outer_ear | 0.62622219 |
135 | MP0001119_abnormal_female_reproductive | 0.62496103 |
136 | MP0006054_spinal_hemorrhage | 0.62182593 |
137 | MP0003699_abnormal_female_reproductive | 0.61468865 |
138 | MP0005193_abnormal_anterior_eye | 0.61335410 |
139 | MP0002111_abnormal_tail_morphology | 0.61077319 |
140 | MP0002796_impaired_skin_barrier | 0.60554002 |
141 | MP0000477_abnormal_intestine_morphology | 0.58879357 |
142 | MP0001186_pigmentation_phenotype | 0.58424871 |
143 | MP0003453_abnormal_keratinocyte_physiol | 0.57694194 |
144 | MP0003936_abnormal_reproductive_system | 0.57194681 |
145 | MP0002234_abnormal_pharynx_morphology | 0.56633954 |
146 | MP0005058_abnormal_lysosome_morphology | 0.56078783 |
147 | MP0003943_abnormal_hepatobiliary_system | 0.56077880 |
148 | MP0010771_integument_phenotype | 0.55779474 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Birth length less than 3rd percentile (HP:0003561) | 4.77867766 |
2 | Breast hypoplasia (HP:0003187) | 4.53181042 |
3 | Carpal bone hypoplasia (HP:0001498) | 3.61852701 |
4 | Abnormality of the anterior horn cell (HP:0006802) | 3.61700146 |
5 | Degeneration of anterior horn cells (HP:0002398) | 3.61700146 |
6 | Ependymoma (HP:0002888) | 3.58153269 |
7 | Increased serum pyruvate (HP:0003542) | 3.54546042 |
8 | Albinism (HP:0001022) | 3.41808335 |
9 | Selective tooth agenesis (HP:0001592) | 3.39792020 |
10 | Impulsivity (HP:0100710) | 3.32215845 |
11 | Abnormality of glycolysis (HP:0004366) | 3.31150982 |
12 | Agnosia (HP:0010524) | 3.23360658 |
13 | Multiple enchondromatosis (HP:0005701) | 3.07651343 |
14 | Rhabdomyosarcoma (HP:0002859) | 2.98417765 |
15 | Patchy hypopigmentation of hair (HP:0011365) | 2.92158702 |
16 | Cerebral hypomyelination (HP:0006808) | 2.86349703 |
17 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.83938071 |
18 | Hypoplasia of the fovea (HP:0007750) | 2.83938071 |
19 | Osteolytic defects of the hand bones (HP:0009699) | 2.81156083 |
20 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.81156083 |
21 | Abnormality of methionine metabolism (HP:0010901) | 2.77279390 |
22 | Abnormality of chromosome stability (HP:0003220) | 2.76427865 |
23 | Oral leukoplakia (HP:0002745) | 2.75662390 |
24 | Rough bone trabeculation (HP:0100670) | 2.73679941 |
25 | Follicular hyperkeratosis (HP:0007502) | 2.73267619 |
26 | Colon cancer (HP:0003003) | 2.69080328 |
27 | Volvulus (HP:0002580) | 2.64521388 |
28 | Aplasia/hypoplasia of the humerus (HP:0006507) | 2.62293072 |
29 | Abnormality of the labia minora (HP:0012880) | 2.58174146 |
30 | Absent radius (HP:0003974) | 2.55422304 |
31 | Increased CSF lactate (HP:0002490) | 2.55374581 |
32 | Biliary tract neoplasm (HP:0100574) | 2.54005335 |
33 | Chromsome breakage (HP:0040012) | 2.53000252 |
34 | Abnormal auditory evoked potentials (HP:0006958) | 2.52979436 |
35 | Reticulocytopenia (HP:0001896) | 2.52700146 |
36 | Patellar aplasia (HP:0006443) | 2.51454889 |
37 | Personality changes (HP:0000751) | 2.51262956 |
38 | Increased serum lactate (HP:0002151) | 2.46977857 |
39 | Increased hepatocellular lipid droplets (HP:0006565) | 2.46733555 |
40 | Premature ovarian failure (HP:0008209) | 2.46579964 |
41 | Abnormality of the astrocytes (HP:0100707) | 2.46374775 |
42 | Astrocytoma (HP:0009592) | 2.46374775 |
43 | White forelock (HP:0002211) | 2.45518953 |
44 | Premature rupture of membranes (HP:0001788) | 2.45416210 |
45 | Secondary amenorrhea (HP:0000869) | 2.44467638 |
46 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.41649360 |
47 | Medulloblastoma (HP:0002885) | 2.41441975 |
48 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.39674842 |
49 | Prominent nose (HP:0000448) | 2.39663926 |
50 | Abnormality of the fovea (HP:0000493) | 2.39022868 |
51 | Pelvic girdle muscle weakness (HP:0003749) | 2.37721801 |
52 | Myelodysplasia (HP:0002863) | 2.36784485 |
53 | Papillary thyroid carcinoma (HP:0002895) | 2.35735942 |
54 | Poor head control (HP:0002421) | 2.35552055 |
55 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.35029675 |
56 | Reduced subcutaneous adipose tissue (HP:0003758) | 2.33664438 |
57 | Aplasia involving forearm bones (HP:0009822) | 2.30177753 |
58 | Absent forearm bone (HP:0003953) | 2.30177753 |
59 | Absent thumb (HP:0009777) | 2.30015851 |
60 | Short humerus (HP:0005792) | 2.29769997 |
61 | Meckel diverticulum (HP:0002245) | 2.29116462 |
62 | Premature graying of hair (HP:0002216) | 2.28395037 |
63 | Cutaneous melanoma (HP:0012056) | 2.27897167 |
64 | Sensory axonal neuropathy (HP:0003390) | 2.27887710 |
65 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.27743424 |
66 | Facial hemangioma (HP:0000329) | 2.26659825 |
67 | Trismus (HP:0000211) | 2.25469129 |
68 | Neoplasm of the pancreas (HP:0002894) | 2.24903159 |
69 | Azoospermia (HP:0000027) | 2.23757324 |
70 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.23286602 |
71 | Thyroid carcinoma (HP:0002890) | 2.23202342 |
72 | Proximal placement of thumb (HP:0009623) | 2.22826663 |
73 | Abnormal protein glycosylation (HP:0012346) | 2.22633870 |
74 | Abnormal glycosylation (HP:0012345) | 2.22633870 |
75 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.22633870 |
76 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.22633870 |
77 | Methylmalonic acidemia (HP:0002912) | 2.21516771 |
78 | Microglossia (HP:0000171) | 2.20509716 |
79 | B lymphocytopenia (HP:0010976) | 2.19854278 |
80 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.19798235 |
81 | Deviation of the thumb (HP:0009603) | 2.19727838 |
82 | Stillbirth (HP:0003826) | 2.19687543 |
83 | Supernumerary spleens (HP:0009799) | 2.17972970 |
84 | Glioma (HP:0009733) | 2.17831142 |
85 | Neoplasm of the peripheral nervous system (HP:0100007) | 2.16747117 |
86 | Abnormal spermatogenesis (HP:0008669) | 2.16091398 |
87 | Metaphyseal cupping (HP:0003021) | 2.14413981 |
88 | Acute necrotizing encephalopathy (HP:0006965) | 2.13640735 |
89 | Abnormality of the ileum (HP:0001549) | 2.13583592 |
90 | Abnormality of the preputium (HP:0100587) | 2.12821433 |
91 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.12619380 |
92 | Horizontal nystagmus (HP:0000666) | 2.12184444 |
93 | Hypokinesia (HP:0002375) | 2.11272955 |
94 | Type I transferrin isoform profile (HP:0003642) | 2.10539557 |
95 | Neoplasm of the oral cavity (HP:0100649) | 2.09814053 |
96 | Autoamputation (HP:0001218) | 2.09599758 |
97 | Sloping forehead (HP:0000340) | 2.09038695 |
98 | Ankle contracture (HP:0006466) | 2.08575232 |
99 | Squamous cell carcinoma (HP:0002860) | 2.08341173 |
100 | Abnormal biliary tract morphology (HP:0012440) | 2.07701374 |
101 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.07178636 |
102 | Abnormality of alanine metabolism (HP:0010916) | 2.07178636 |
103 | Hyperalaninemia (HP:0003348) | 2.07178636 |
104 | Spinal muscular atrophy (HP:0007269) | 2.07114971 |
105 | Renal Fanconi syndrome (HP:0001994) | 2.06824170 |
106 | Posterior subcapsular cataract (HP:0007787) | 2.06208520 |
107 | Progressive macrocephaly (HP:0004481) | 2.05786505 |
108 | Upper motor neuron abnormality (HP:0002127) | 2.05445363 |
109 | Microvesicular hepatic steatosis (HP:0001414) | 2.05342325 |
110 | Abnormality of the umbilical cord (HP:0010881) | 2.05108750 |
111 | Generalized hypopigmentation (HP:0007513) | 2.04716252 |
112 | Delayed gross motor development (HP:0002194) | 2.04638363 |
113 | Shoulder girdle muscle weakness (HP:0003547) | 2.04435376 |
114 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.03549378 |
115 | Small epiphyses (HP:0010585) | 2.03167841 |
116 | Orthostatic hypotension (HP:0001278) | 2.02497506 |
117 | Entropion (HP:0000621) | 2.01931753 |
118 | Short nail (HP:0001799) | 2.01647600 |
119 | Basal cell carcinoma (HP:0002671) | 2.00638762 |
120 | Poikiloderma (HP:0001029) | 1.99824672 |
121 | Abnormality of the fetal cardiovascular system (HP:0010948) | 1.99593690 |
122 | Abnormal umbilical cord blood vessels (HP:0011403) | 1.99593690 |
123 | Single umbilical artery (HP:0001195) | 1.99593690 |
124 | Bone marrow hypocellularity (HP:0005528) | 1.99489740 |
125 | Redundant skin (HP:0001582) | 1.99113736 |
126 | Abnormality of the lower motor neuron (HP:0002366) | 1.99100583 |
127 | Cafe-au-lait spot (HP:0000957) | 1.98920487 |
128 | Lipid accumulation in hepatocytes (HP:0006561) | 1.98685703 |
129 | Abnormal trabecular bone morphology (HP:0100671) | 1.98604241 |
130 | Mitochondrial inheritance (HP:0001427) | 1.98542202 |
131 | Spastic diplegia (HP:0001264) | 1.98356117 |
132 | Reduced antithrombin III activity (HP:0001976) | 1.98192647 |
133 | Neoplasm of striated muscle (HP:0009728) | 1.97673764 |
134 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.97380938 |
135 | Hypopigmentation of the fundus (HP:0007894) | 1.96439017 |
136 | Freckling (HP:0001480) | 1.95652221 |
137 | Duodenal stenosis (HP:0100867) | 1.94226297 |
138 | Small intestinal stenosis (HP:0012848) | 1.94226297 |
139 | Megaloblastic anemia (HP:0001889) | 1.93764190 |
140 | Hepatocellular necrosis (HP:0001404) | 1.92909657 |
141 | 11 pairs of ribs (HP:0000878) | 1.92773003 |
142 | CNS hypomyelination (HP:0003429) | 1.92304943 |
143 | Missing ribs (HP:0000921) | 1.91961128 |
144 | Neoplasm of the colon (HP:0100273) | 1.91585553 |
145 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.91402431 |
146 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.91402431 |
147 | Acute encephalopathy (HP:0006846) | 1.90846663 |
148 | Glossoptosis (HP:0000162) | 1.90786595 |
149 | Long clavicles (HP:0000890) | 1.90749911 |
150 | Irregular epiphyses (HP:0010582) | 1.90663331 |
151 | Abnormalities of placenta or umbilical cord (HP:0001194) | 1.90214936 |
152 | Sparse eyelashes (HP:0000653) | 1.89786975 |
153 | Ocular albinism (HP:0001107) | 1.89658879 |
154 | Neoplasm of the adrenal gland (HP:0100631) | 1.89508656 |
155 | Opisthotonus (HP:0002179) | 1.89333763 |
156 | Embryonal renal neoplasm (HP:0011794) | 1.88269599 |
157 | Gonadotropin excess (HP:0000837) | 1.87385832 |
158 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.86105308 |
159 | Hepatic necrosis (HP:0002605) | 1.85787152 |
160 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.84000896 |
161 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.84000896 |
162 | Amaurosis fugax (HP:0100576) | 1.83524065 |
163 | Melanoma (HP:0002861) | 1.83460871 |
164 | Microretrognathia (HP:0000308) | 1.83424829 |
165 | Conjunctival telangiectasia (HP:0000524) | 1.83029217 |
166 | Amniotic constriction ring (HP:0009775) | 1.83021459 |
167 | Abnormality of placental membranes (HP:0011409) | 1.83021459 |
168 | Abnormality of pyrimidine metabolism (HP:0004353) | 1.82769557 |
169 | Abnormal cartilage morphology (HP:0002763) | 1.82746991 |
170 | Aplasia/Hypoplasia of the macula (HP:0008059) | 1.82608094 |
171 | Atresia of the external auditory canal (HP:0000413) | 1.82043332 |
172 | Breast aplasia (HP:0100783) | 1.81919110 |
173 | Macrocytic anemia (HP:0001972) | 1.81337148 |
174 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 1.80591714 |
175 | Overlapping toe (HP:0001845) | 1.80289401 |
176 | Autoimmune hemolytic anemia (HP:0001890) | 1.79387839 |
177 | Abdominal situs inversus (HP:0003363) | 1.79225147 |
178 | Abnormality of abdominal situs (HP:0011620) | 1.79225147 |
Rank | Gene Set | Z-score |
---|---|---|
1 | WEE1 | 4.44169129 |
2 | BUB1 | 3.55686036 |
3 | CDC7 | 3.42873742 |
4 | EIF2AK1 | 3.19540576 |
5 | NEK2 | 2.83726485 |
6 | MST4 | 2.80989284 |
7 | TTK | 2.45365889 |
8 | PDK4 | 2.42088745 |
9 | PDK3 | 2.42088745 |
10 | BMPR1B | 2.40375507 |
11 | EPHA2 | 2.33341812 |
12 | NEK1 | 2.29576374 |
13 | BRSK2 | 2.23175127 |
14 | TRIM28 | 2.18687634 |
15 | EIF2AK3 | 2.07439750 |
16 | PLK4 | 2.07095551 |
17 | SCYL2 | 2.05563096 |
18 | TSSK6 | 2.03787782 |
19 | PKN2 | 1.98989089 |
20 | SRPK1 | 1.92816149 |
21 | ERBB3 | 1.88802085 |
22 | TESK2 | 1.86947387 |
23 | PLK1 | 1.81017687 |
24 | MAP3K12 | 1.76205353 |
25 | ACVR1B | 1.75910041 |
26 | RPS6KB2 | 1.74221874 |
27 | CDK12 | 1.73394451 |
28 | PDK2 | 1.66810722 |
29 | RPS6KA4 | 1.61335691 |
30 | PNCK | 1.58257849 |
31 | MAP3K8 | 1.55689896 |
32 | PLK3 | 1.53353160 |
33 | TAF1 | 1.52314500 |
34 | AURKB | 1.48466122 |
35 | NME2 | 1.48142057 |
36 | DYRK3 | 1.43138877 |
37 | LATS1 | 1.41844583 |
38 | CHEK2 | 1.41818993 |
39 | ATR | 1.41502555 |
40 | STK3 | 1.40768098 |
41 | CDK7 | 1.37273164 |
42 | STK10 | 1.37057591 |
43 | BCR | 1.33163887 |
44 | TESK1 | 1.33046049 |
45 | CHEK1 | 1.23517881 |
46 | PASK | 1.22441792 |
47 | EEF2K | 1.17204624 |
48 | TLK1 | 1.16971762 |
49 | PLK2 | 1.14846241 |
50 | CDK8 | 1.13760462 |
51 | AURKA | 1.13233612 |
52 | CDK4 | 1.13006999 |
53 | CSNK1A1L | 1.08378565 |
54 | CSNK1G3 | 1.05989705 |
55 | CSNK1G1 | 1.05847462 |
56 | VRK2 | 1.05156623 |
57 | PBK | 1.04810964 |
58 | PAK4 | 1.00901184 |
59 | STK4 | 1.00567030 |
60 | FRK | 0.95764336 |
61 | CSNK1G2 | 0.94712393 |
62 | PIM1 | 0.94612542 |
63 | ZAK | 0.94610717 |
64 | MYLK | 0.93028869 |
65 | TRIB3 | 0.88671594 |
66 | BRSK1 | 0.87395303 |
67 | ATM | 0.86817230 |
68 | MAP4K2 | 0.84534690 |
69 | SIK3 | 0.84488982 |
70 | FLT3 | 0.82149019 |
71 | ALK | 0.81252898 |
72 | MARK3 | 0.80332742 |
73 | TGFBR1 | 0.79219056 |
74 | MET | 0.77783645 |
75 | LATS2 | 0.77311789 |
76 | CDK2 | 0.76688288 |
77 | CDK6 | 0.76297681 |
78 | CAMKK2 | 0.74651120 |
79 | IRAK3 | 0.72032959 |
80 | MST1R | 0.71919038 |
81 | STK39 | 0.70970293 |
82 | MKNK1 | 0.68475487 |
83 | LRRK2 | 0.66673551 |
84 | VRK1 | 0.66175388 |
85 | MAP2K3 | 0.65471636 |
86 | PAK1 | 0.64767365 |
87 | MTOR | 0.64422439 |
88 | FER | 0.64278228 |
89 | MAP2K7 | 0.63276197 |
90 | PIK3CG | 0.61592481 |
91 | CSNK2A2 | 0.59962971 |
92 | AKT3 | 0.59450020 |
93 | STK38L | 0.59131469 |
94 | CDK1 | 0.55545862 |
95 | BRAF | 0.55292990 |
96 | NEK9 | 0.53987131 |
97 | BMPR2 | 0.53205627 |
98 | BRD4 | 0.51970081 |
99 | TRPM7 | 0.50692090 |
100 | MELK | 0.50244907 |
101 | GRK7 | 0.49718347 |
102 | TEC | 0.48666017 |
103 | JAK3 | 0.47597324 |
104 | BMX | 0.46945493 |
105 | CSNK2A1 | 0.45874194 |
106 | MAP3K4 | 0.45370212 |
107 | RPS6KA5 | 0.44896495 |
108 | CLK1 | 0.43226845 |
109 | CSNK1E | 0.43090842 |
110 | PRKCI | 0.42945187 |
111 | NEK6 | 0.42628412 |
112 | PAK2 | 0.41573724 |
113 | RAF1 | 0.40328177 |
114 | TTN | 0.39892274 |
115 | MAP3K3 | 0.39163989 |
116 | MAP3K5 | 0.39085443 |
117 | PIM2 | 0.38413904 |
118 | CDK9 | 0.36708269 |
119 | CSNK1D | 0.35823482 |
120 | KSR1 | 0.35347832 |
121 | MUSK | 0.33676587 |
122 | DAPK1 | 0.33067766 |
123 | EIF2AK2 | 0.32983162 |
124 | NUAK1 | 0.32479807 |
125 | ILK | 0.32034275 |
126 | DDR2 | 0.31276590 |
127 | WNK3 | 0.30695731 |
128 | JAK1 | 0.30311457 |
129 | MAP4K1 | 0.30245831 |
130 | PRKDC | 0.29679718 |
131 | MKNK2 | 0.27797278 |
132 | TYRO3 | 0.27731762 |
133 | AKT2 | 0.27677499 |
134 | CCNB1 | 0.26456653 |
135 | ABL2 | 0.25220305 |
136 | FGFR1 | 0.23636337 |
137 | MAPKAPK3 | 0.22401674 |
138 | LIMK1 | 0.21819667 |
139 | STK16 | 0.21808530 |
140 | ERBB4 | 0.20251224 |
141 | MAP3K10 | 0.19004454 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.97841428 |
2 | DNA replication_Homo sapiens_hsa03030 | 3.95063889 |
3 | Mismatch repair_Homo sapiens_hsa03430 | 3.55034408 |
4 | RNA transport_Homo sapiens_hsa03013 | 3.51773706 |
5 | One carbon pool by folate_Homo sapiens_hsa00670 | 3.00491195 |
6 | Protein export_Homo sapiens_hsa03060 | 2.91741793 |
7 | Proteasome_Homo sapiens_hsa03050 | 2.91250788 |
8 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.88263555 |
9 | Spliceosome_Homo sapiens_hsa03040 | 2.82767784 |
10 | RNA polymerase_Homo sapiens_hsa03020 | 2.71909861 |
11 | Cell cycle_Homo sapiens_hsa04110 | 2.71176641 |
12 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 2.51812666 |
13 | * Nucleotide excision repair_Homo sapiens_hsa03420 | 2.34032636 |
14 | Homologous recombination_Homo sapiens_hsa03440 | 2.23884272 |
15 | Base excision repair_Homo sapiens_hsa03410 | 2.17306674 |
16 | Ribosome_Homo sapiens_hsa03010 | 2.07634768 |
17 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.01061311 |
18 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.91724667 |
19 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.84470302 |
20 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.80586843 |
21 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.72947749 |
22 | RNA degradation_Homo sapiens_hsa03018 | 1.68943436 |
23 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.65584350 |
24 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.63554071 |
25 | * Basal transcription factors_Homo sapiens_hsa03022 | 1.63482108 |
26 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.57084240 |
27 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.51524217 |
28 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.49455793 |
29 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.45175121 |
30 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.39694123 |
31 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.37856755 |
32 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.28113858 |
33 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.24505318 |
34 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.22959137 |
35 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.20603438 |
36 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.19755214 |
37 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.18940165 |
38 | * Viral carcinogenesis_Homo sapiens_hsa05203 | 1.15736485 |
39 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.15631300 |
40 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.12423319 |
41 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.09100400 |
42 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.08228145 |
43 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.01942400 |
44 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.00267143 |
45 | Purine metabolism_Homo sapiens_hsa00230 | 0.98599448 |
46 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.97878667 |
47 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.95333579 |
48 | Carbon metabolism_Homo sapiens_hsa01200 | 0.90425685 |
49 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.86975671 |
50 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.86930771 |
51 | Legionellosis_Homo sapiens_hsa05134 | 0.86136964 |
52 | Parkinsons disease_Homo sapiens_hsa05012 | 0.85195431 |
53 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.83220831 |
54 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.82008336 |
55 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.79400144 |
56 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.79174625 |
57 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.75558277 |
58 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.72586033 |
59 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.70798472 |
60 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.70422408 |
61 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.69999355 |
62 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.69098917 |
63 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.68956318 |
64 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.68931942 |
65 | Huntingtons disease_Homo sapiens_hsa05016 | 0.68303615 |
66 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.67678977 |
67 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.65338050 |
68 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.64416248 |
69 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.63921805 |
70 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.62387892 |
71 | Circadian rhythm_Homo sapiens_hsa04710 | 0.61901243 |
72 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.60630840 |
73 | HTLV-I infection_Homo sapiens_hsa05166 | 0.58516633 |
74 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.57221365 |
75 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.55901014 |
76 | Apoptosis_Homo sapiens_hsa04210 | 0.54979823 |
77 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.54184366 |
78 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.52773075 |
79 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.52327241 |
80 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.51192752 |
81 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.50118886 |
82 | Thyroid cancer_Homo sapiens_hsa05216 | 0.47230482 |
83 | Shigellosis_Homo sapiens_hsa05131 | 0.47089778 |
84 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.45193457 |
85 | Sulfur relay system_Homo sapiens_hsa04122 | 0.44860017 |
86 | Lysosome_Homo sapiens_hsa04142 | 0.42819383 |
87 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.42135657 |
88 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.40487134 |
89 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.40252134 |
90 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.40105651 |
91 | Peroxisome_Homo sapiens_hsa04146 | 0.39127183 |
92 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.38254154 |
93 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.38131196 |
94 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.36771358 |
95 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.36459996 |
96 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.35339051 |
97 | Galactose metabolism_Homo sapiens_hsa00052 | 0.35221726 |
98 | Hepatitis B_Homo sapiens_hsa05161 | 0.34391981 |
99 | Bladder cancer_Homo sapiens_hsa05219 | 0.33427525 |
100 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.33040900 |
101 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.32699964 |
102 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.32340731 |
103 | Measles_Homo sapiens_hsa05162 | 0.32092947 |
104 | Prostate cancer_Homo sapiens_hsa05215 | 0.32029367 |
105 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.29685171 |
106 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.29547302 |
107 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.28571346 |
108 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.28450041 |
109 | Alcoholism_Homo sapiens_hsa05034 | 0.26910683 |
110 | Alzheimers disease_Homo sapiens_hsa05010 | 0.26525330 |
111 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.26270828 |
112 | Adherens junction_Homo sapiens_hsa04520 | 0.25370489 |
113 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.25229505 |
114 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.25211280 |
115 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.25167922 |
116 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.25066369 |
117 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.23722279 |
118 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.23608001 |
119 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.23155006 |
120 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.21264249 |
121 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.21117794 |
122 | Influenza A_Homo sapiens_hsa05164 | 0.20840217 |
123 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.20258178 |
124 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.19960359 |
125 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.19727261 |
126 | Tight junction_Homo sapiens_hsa04530 | 0.18665742 |
127 | Lysine degradation_Homo sapiens_hsa00310 | 0.18033677 |
128 | Metabolic pathways_Homo sapiens_hsa01100 | 0.17474659 |
129 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.16249224 |
130 | Colorectal cancer_Homo sapiens_hsa05210 | 0.15726236 |
131 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.13466139 |
132 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.12457669 |
133 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.11155094 |
134 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.11115863 |
135 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.10905004 |
136 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.10093357 |