

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | proteasome assembly (GO:0043248) | 4.91972306 |
| 2 | chromatin remodeling at centromere (GO:0031055) | 4.65576170 |
| 3 | CENP-A containing nucleosome assembly (GO:0034080) | 4.62741585 |
| 4 | DNA double-strand break processing (GO:0000729) | 4.24455371 |
| 5 | ribosome assembly (GO:0042255) | 4.07723055 |
| 6 | establishment of integrated proviral latency (GO:0075713) | 4.07201887 |
| 7 | histone exchange (GO:0043486) | 3.95756944 |
| 8 | mitotic metaphase plate congression (GO:0007080) | 3.94414525 |
| 9 | protein localization to kinetochore (GO:0034501) | 3.91046287 |
| 10 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.87872883 |
| 11 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.87796808 |
| 12 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.85126846 |
| 13 | DNA ligation (GO:0006266) | 3.79208558 |
| 14 | metaphase plate congression (GO:0051310) | 3.73786974 |
| 15 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.73683695 |
| 16 | non-recombinational repair (GO:0000726) | 3.73683695 |
| 17 | DNA strand elongation (GO:0022616) | 3.71900850 |
| 18 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.69323309 |
| 19 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.69114183 |
| 20 | cullin deneddylation (GO:0010388) | 3.64848889 |
| 21 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.62376726 |
| 22 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.62058207 |
| 23 | spindle checkpoint (GO:0031577) | 3.60235104 |
| 24 | purine nucleobase biosynthetic process (GO:0009113) | 3.58885131 |
| 25 | IMP biosynthetic process (GO:0006188) | 3.57760091 |
| 26 | protein deneddylation (GO:0000338) | 3.57211768 |
| 27 | mitotic sister chromatid segregation (GO:0000070) | 3.54987346 |
| 28 | mitotic spindle checkpoint (GO:0071174) | 3.54496166 |
| 29 | DNA replication-independent nucleosome organization (GO:0034724) | 3.54451607 |
| 30 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.54451607 |
| 31 | DNA replication checkpoint (GO:0000076) | 3.52671576 |
| 32 | nucleobase biosynthetic process (GO:0046112) | 3.51922263 |
| 33 | negative regulation of ligase activity (GO:0051352) | 3.50468443 |
| 34 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.50468443 |
| 35 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.47979951 |
| 36 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.47785701 |
| 37 | regulation of helicase activity (GO:0051095) | 3.46768800 |
| 38 | rRNA modification (GO:0000154) | 3.43952710 |
| 39 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.42951393 |
| 40 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.42951393 |
| 41 | maturation of 5.8S rRNA (GO:0000460) | 3.42739611 |
| 42 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.39818727 |
| 43 | tRNA aminoacylation for protein translation (GO:0006418) | 3.39550794 |
| 44 | sister chromatid segregation (GO:0000819) | 3.39304766 |
| 45 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.38759660 |
| 46 | amino acid activation (GO:0043038) | 3.37915735 |
| 47 | tRNA aminoacylation (GO:0043039) | 3.37915735 |
| 48 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.35854989 |
| 49 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 3.35854989 |
| 50 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.35854989 |
| 51 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.35854989 |
| 52 | negative regulation of sister chromatid segregation (GO:0033046) | 3.35854989 |
| 53 | telomere maintenance via recombination (GO:0000722) | 3.34856775 |
| 54 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.34581851 |
| 55 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.34581851 |
| 56 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.34267700 |
| 57 | mitotic recombination (GO:0006312) | 3.34029035 |
| 58 | regulation of centriole replication (GO:0046599) | 3.34018175 |
| 59 | negative regulation of chromosome segregation (GO:0051985) | 3.32357334 |
| 60 | nuclear pore organization (GO:0006999) | 3.31822691 |
| 61 | kinetochore organization (GO:0051383) | 3.29326723 |
| 62 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.28350523 |
| 63 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.28350523 |
| 64 | isotype switching (GO:0045190) | 3.28350523 |
| 65 | respiratory chain complex IV assembly (GO:0008535) | 3.28259023 |
| 66 | mitotic nuclear envelope disassembly (GO:0007077) | 3.27709903 |
| 67 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.25337669 |
| 68 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.25337669 |
| 69 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.24681660 |
| 70 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 3.23440374 |
| 71 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 3.23440374 |
| 72 | spindle assembly checkpoint (GO:0071173) | 3.22692158 |
| 73 | rRNA methylation (GO:0031167) | 3.22628586 |
| 74 | mitotic spindle assembly checkpoint (GO:0007094) | 3.20520891 |
| 75 | mitochondrial RNA metabolic process (GO:0000959) | 3.18215283 |
| 76 | establishment of viral latency (GO:0019043) | 3.17228560 |
| 77 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.16483748 |
| 78 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.15991286 |
| 79 | synapsis (GO:0007129) | 3.15703045 |
| 80 | replication fork processing (GO:0031297) | 3.14959232 |
| 81 | protein K6-linked ubiquitination (GO:0085020) | 3.14538852 |
| 82 | protein localization to chromosome, centromeric region (GO:0071459) | 3.14538179 |
| 83 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.12701571 |
| 84 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.12425978 |
| 85 | kinetochore assembly (GO:0051382) | 3.11195386 |
| 86 | IMP metabolic process (GO:0046040) | 3.10964472 |
| 87 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.10790287 |
| 88 | establishment of chromosome localization (GO:0051303) | 3.10545243 |
| 89 | pseudouridine synthesis (GO:0001522) | 3.09931412 |
| 90 | negative regulation of DNA recombination (GO:0045910) | 3.08256921 |
| 91 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.07525772 |
| 92 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.07525772 |
| 93 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.07525772 |
| 94 | histone mRNA metabolic process (GO:0008334) | 3.07418476 |
| 95 | regulation of chromosome segregation (GO:0051983) | 3.06487899 |
| 96 | regulation of sister chromatid segregation (GO:0033045) | 3.06017561 |
| 97 | regulation of mitotic sister chromatid separation (GO:0010965) | 3.06017561 |
| 98 | regulation of mitotic sister chromatid segregation (GO:0033047) | 3.06017561 |
| 99 | positive regulation of ligase activity (GO:0051351) | 3.05481670 |
| 100 | nuclear pore complex assembly (GO:0051292) | 3.04991529 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 5.85163976 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.88896626 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.85156519 |
| 4 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.83050323 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.43369647 |
| 6 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.09854350 |
| 7 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.87171163 |
| 8 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.86265621 |
| 9 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.78551949 |
| 10 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.68419078 |
| 11 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.67789566 |
| 12 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.59411071 |
| 13 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.57642446 |
| 14 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.50993246 |
| 15 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.50734496 |
| 16 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.49404763 |
| 17 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.48606505 |
| 18 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.47692424 |
| 19 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.41178787 |
| 20 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.38893400 |
| 21 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.22107576 |
| 22 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.18170842 |
| 23 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 2.16504951 |
| 24 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 2.14594915 |
| 25 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.12398985 |
| 26 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.07585113 |
| 27 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.07571928 |
| 28 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.89443246 |
| 29 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.86465724 |
| 30 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.86245021 |
| 31 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.83053497 |
| 32 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.82334277 |
| 33 | EWS_26573619_Chip-Seq_HEK293_Human | 1.77342540 |
| 34 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.76687153 |
| 35 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.75998717 |
| 36 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.74981708 |
| 37 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.73886451 |
| 38 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.71638235 |
| 39 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.71621297 |
| 40 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.70963003 |
| 41 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.70434051 |
| 42 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.70016253 |
| 43 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.68851936 |
| 44 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.65863607 |
| 45 | FUS_26573619_Chip-Seq_HEK293_Human | 1.65658427 |
| 46 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.57807511 |
| 47 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.55015854 |
| 48 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.52466652 |
| 49 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.44781749 |
| 50 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.44248308 |
| 51 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.39092734 |
| 52 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.36607288 |
| 53 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.36459964 |
| 54 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.35003475 |
| 55 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.29887068 |
| 56 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.27202343 |
| 57 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.25555915 |
| 58 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.25302191 |
| 59 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.22357785 |
| 60 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.18897638 |
| 61 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.15185078 |
| 62 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.12746308 |
| 63 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.10612311 |
| 64 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.08583315 |
| 65 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.07396152 |
| 66 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.04607933 |
| 67 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.02547609 |
| 68 | P300_19829295_ChIP-Seq_ESCs_Human | 1.02305935 |
| 69 | VDR_22108803_ChIP-Seq_LS180_Human | 1.01789475 |
| 70 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.01761243 |
| 71 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.00422422 |
| 72 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.99463731 |
| 73 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.96131319 |
| 74 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.95052720 |
| 75 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.94982145 |
| 76 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.91827863 |
| 77 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.89741148 |
| 78 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.89366669 |
| 79 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.88617377 |
| 80 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.88453617 |
| 81 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.88237416 |
| 82 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.85846261 |
| 83 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 0.85714076 |
| 84 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.85643045 |
| 85 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.85283662 |
| 86 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.84575990 |
| 87 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.83339915 |
| 88 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.82759328 |
| 89 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.82690782 |
| 90 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.81226019 |
| 91 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.80471354 |
| 92 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.80154254 |
| 93 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.78896006 |
| 94 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.78413413 |
| 95 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.77329692 |
| 96 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.76843652 |
| 97 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.74237144 |
| 98 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.71451340 |
| 99 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.71332642 |
| 100 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.70643264 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0010094_abnormal_chromosome_stability | 5.00074119 |
| 2 | MP0008058_abnormal_DNA_repair | 4.79845723 |
| 3 | MP0003693_abnormal_embryo_hatching | 4.32474622 |
| 4 | MP0008057_abnormal_DNA_replication | 4.19506188 |
| 5 | MP0003111_abnormal_nucleus_morphology | 3.75493913 |
| 6 | MP0004957_abnormal_blastocyst_morpholog | 3.75278076 |
| 7 | MP0008877_abnormal_DNA_methylation | 3.65437674 |
| 8 | MP0003077_abnormal_cell_cycle | 3.08829607 |
| 9 | MP0009697_abnormal_copulation | 3.01319944 |
| 10 | MP0003718_maternal_effect | 2.93180030 |
| 11 | MP0008007_abnormal_cellular_replicative | 2.92433947 |
| 12 | MP0003786_premature_aging | 2.80091046 |
| 13 | MP0008932_abnormal_embryonic_tissue | 2.54845372 |
| 14 | MP0000372_irregular_coat_pigmentation | 2.12004475 |
| 15 | MP0006035_abnormal_mitochondrial_morpho | 2.02424569 |
| 16 | MP0002102_abnormal_ear_morphology | 2.02198889 |
| 17 | MP0006072_abnormal_retinal_apoptosis | 1.85025815 |
| 18 | MP0003806_abnormal_nucleotide_metabolis | 1.80777805 |
| 19 | MP0010307_abnormal_tumor_latency | 1.78709730 |
| 20 | MP0001529_abnormal_vocalization | 1.72595541 |
| 21 | MP0006036_abnormal_mitochondrial_physio | 1.67204175 |
| 22 | MP0002254_reproductive_system_inflammat | 1.63212716 |
| 23 | MP0003186_abnormal_redox_activity | 1.62236751 |
| 24 | MP0001661_extended_life_span | 1.49110496 |
| 25 | MP0001730_embryonic_growth_arrest | 1.48924604 |
| 26 | MP0004147_increased_porphyrin_level | 1.43008852 |
| 27 | MP0003941_abnormal_skin_development | 1.40904827 |
| 28 | MP0006054_spinal_hemorrhage | 1.40431139 |
| 29 | MP0001697_abnormal_embryo_size | 1.38009982 |
| 30 | MP0001929_abnormal_gametogenesis | 1.36024310 |
| 31 | MP0000350_abnormal_cell_proliferation | 1.35922935 |
| 32 | MP0005075_abnormal_melanosome_morpholog | 1.34973642 |
| 33 | MP0003890_abnormal_embryonic-extraembry | 1.32895064 |
| 34 | MP0000358_abnormal_cell_content/ | 1.30742288 |
| 35 | MP0005084_abnormal_gallbladder_morpholo | 1.30525736 |
| 36 | MP0008789_abnormal_olfactory_epithelium | 1.29526710 |
| 37 | MP0002938_white_spotting | 1.28005714 |
| 38 | MP0000647_abnormal_sebaceous_gland | 1.26402023 |
| 39 | MP0005253_abnormal_eye_physiology | 1.26239058 |
| 40 | MP0005408_hypopigmentation | 1.25712741 |
| 41 | MP0001293_anophthalmia | 1.24785443 |
| 42 | MP0002163_abnormal_gland_morphology | 1.21830901 |
| 43 | MP0002210_abnormal_sex_determination | 1.21356635 |
| 44 | MP0010352_gastrointestinal_tract_polyps | 1.19582601 |
| 45 | MP0003567_abnormal_fetal_cardiomyocyte | 1.18970486 |
| 46 | MP0001672_abnormal_embryogenesis/_devel | 1.18737335 |
| 47 | MP0005380_embryogenesis_phenotype | 1.18737335 |
| 48 | MP0003195_calcinosis | 1.14847982 |
| 49 | MP0000427_abnormal_hair_cycle | 1.13614970 |
| 50 | MP0000653_abnormal_sex_gland | 1.12637397 |
| 51 | MP0000313_abnormal_cell_death | 1.12294494 |
| 52 | MP0001764_abnormal_homeostasis | 1.11725767 |
| 53 | MP0005395_other_phenotype | 1.11141992 |
| 54 | MP0005379_endocrine/exocrine_gland_phen | 1.10218094 |
| 55 | MP0002090_abnormal_vision | 1.09642008 |
| 56 | MP0001145_abnormal_male_reproductive | 1.07454416 |
| 57 | MP0003121_genomic_imprinting | 1.03854427 |
| 58 | MP0003984_embryonic_growth_retardation | 1.03528487 |
| 59 | MP0002084_abnormal_developmental_patter | 1.03094280 |
| 60 | MP0002080_prenatal_lethality | 1.01740560 |
| 61 | MP0002088_abnormal_embryonic_growth/wei | 1.01025927 |
| 62 | MP0001119_abnormal_female_reproductive | 1.00303773 |
| 63 | MP0005551_abnormal_eye_electrophysiolog | 0.98460239 |
| 64 | MP0003937_abnormal_limbs/digits/tail_de | 0.93000966 |
| 65 | MP0000516_abnormal_urinary_system | 0.92049745 |
| 66 | MP0005367_renal/urinary_system_phenotyp | 0.92049745 |
| 67 | MP0002085_abnormal_embryonic_tissue | 0.90642070 |
| 68 | MP0005645_abnormal_hypothalamus_physiol | 0.89429603 |
| 69 | MP0002019_abnormal_tumor_incidence | 0.88829867 |
| 70 | MP0005332_abnormal_amino_acid | 0.86511844 |
| 71 | MP0003698_abnormal_male_reproductive | 0.85846707 |
| 72 | MP0002160_abnormal_reproductive_system | 0.85755013 |
| 73 | MP0003221_abnormal_cardiomyocyte_apopto | 0.85443574 |
| 74 | MP0001984_abnormal_olfaction | 0.84575046 |
| 75 | MP0002751_abnormal_autonomic_nervous | 0.83589986 |
| 76 | MP0005394_taste/olfaction_phenotype | 0.81465388 |
| 77 | MP0005499_abnormal_olfactory_system | 0.81465388 |
| 78 | MP0004197_abnormal_fetal_growth/weight/ | 0.78892088 |
| 79 | MP0005389_reproductive_system_phenotype | 0.78769482 |
| 80 | MP0000569_abnormal_digit_pigmentation | 0.78319613 |
| 81 | MP0002233_abnormal_nose_morphology | 0.76432125 |
| 82 | MP0006292_abnormal_olfactory_placode | 0.76056803 |
| 83 | MP0002396_abnormal_hematopoietic_system | 0.75282866 |
| 84 | MP0009672_abnormal_birth_weight | 0.72982491 |
| 85 | MP0002837_dystrophic_cardiac_calcinosis | 0.72088277 |
| 86 | MP0009703_decreased_birth_body | 0.71875745 |
| 87 | MP0002736_abnormal_nociception_after | 0.71577062 |
| 88 | MP0001324_abnormal_eye_pigmentation | 0.71544628 |
| 89 | MP0005636_abnormal_mineral_homeostasis | 0.70077406 |
| 90 | MP0008995_early_reproductive_senescence | 0.68729666 |
| 91 | MP0008872_abnormal_physiological_respon | 0.67737716 |
| 92 | MP0005391_vision/eye_phenotype | 0.67276444 |
| 93 | MP0001286_abnormal_eye_development | 0.66546659 |
| 94 | MP0004215_abnormal_myocardial_fiber | 0.65760706 |
| 95 | MP0001188_hyperpigmentation | 0.65196249 |
| 96 | MP0003656_abnormal_erythrocyte_physiolo | 0.64667630 |
| 97 | MP0002086_abnormal_extraembryonic_tissu | 0.63968861 |
| 98 | MP0005647_abnormal_sex_gland | 0.63937259 |
| 99 | MP0001919_abnormal_reproductive_system | 0.63341146 |
| 100 | MP0001485_abnormal_pinna_reflex | 0.62347047 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Chromsome breakage (HP:0040012) | 4.03159690 |
| 2 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.86075922 |
| 3 | Abnormality of chromosome stability (HP:0003220) | 3.64176712 |
| 4 | Meckel diverticulum (HP:0002245) | 3.57266275 |
| 5 | Abnormality of the ileum (HP:0001549) | 3.43650743 |
| 6 | Abnormality of the labia minora (HP:0012880) | 3.22090677 |
| 7 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 3.13208136 |
| 8 | Increased CSF lactate (HP:0002490) | 3.12624410 |
| 9 | Abnormality of the preputium (HP:0100587) | 3.10450379 |
| 10 | Acute necrotizing encephalopathy (HP:0006965) | 3.07666156 |
| 11 | Increased hepatocellular lipid droplets (HP:0006565) | 3.01897408 |
| 12 | Acute encephalopathy (HP:0006846) | 3.01095628 |
| 13 | Abnormality of glycolysis (HP:0004366) | 2.93825404 |
| 14 | Methylmalonic acidemia (HP:0002912) | 2.91565548 |
| 15 | Colon cancer (HP:0003003) | 2.88786140 |
| 16 | Lipid accumulation in hepatocytes (HP:0006561) | 2.82168767 |
| 17 | Abnormal lung lobation (HP:0002101) | 2.81497815 |
| 18 | Mitochondrial inheritance (HP:0001427) | 2.78666573 |
| 19 | Hepatocellular necrosis (HP:0001404) | 2.71571433 |
| 20 | Renal cortical cysts (HP:0000803) | 2.70088053 |
| 21 | Duodenal stenosis (HP:0100867) | 2.69443704 |
| 22 | Small intestinal stenosis (HP:0012848) | 2.69443704 |
| 23 | Progressive macrocephaly (HP:0004481) | 2.68361720 |
| 24 | Abnormality of alanine metabolism (HP:0010916) | 2.68209305 |
| 25 | Hyperalaninemia (HP:0003348) | 2.68209305 |
| 26 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.68209305 |
| 27 | Increased serum pyruvate (HP:0003542) | 2.65820043 |
| 28 | Hyperglycinemia (HP:0002154) | 2.65443916 |
| 29 | Increased serum lactate (HP:0002151) | 2.64323363 |
| 30 | Abnormality of methionine metabolism (HP:0010901) | 2.62258587 |
| 31 | Neoplasm of the adrenal gland (HP:0100631) | 2.61949267 |
| 32 | Intestinal atresia (HP:0011100) | 2.60666839 |
| 33 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.59059496 |
| 34 | Hepatic necrosis (HP:0002605) | 2.56926710 |
| 35 | Abnormality of the duodenum (HP:0002246) | 2.52759002 |
| 36 | Type I transferrin isoform profile (HP:0003642) | 2.52296745 |
| 37 | Sloping forehead (HP:0000340) | 2.49790364 |
| 38 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.43859879 |
| 39 | Abnormality of serum amino acid levels (HP:0003112) | 2.33744922 |
| 40 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.32542276 |
| 41 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.32542276 |
| 42 | Abnormal protein glycosylation (HP:0012346) | 2.32542276 |
| 43 | Abnormal glycosylation (HP:0012345) | 2.32542276 |
| 44 | Embryonal renal neoplasm (HP:0011794) | 2.32098066 |
| 45 | Methylmalonic aciduria (HP:0012120) | 2.31553212 |
| 46 | Birth length less than 3rd percentile (HP:0003561) | 2.31142123 |
| 47 | Lactic acidosis (HP:0003128) | 2.30356480 |
| 48 | Volvulus (HP:0002580) | 2.29671181 |
| 49 | Cerebral edema (HP:0002181) | 2.29525923 |
| 50 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.29479898 |
| 51 | Medial flaring of the eyebrow (HP:0010747) | 2.22491771 |
| 52 | Ependymoma (HP:0002888) | 2.20746518 |
| 53 | Myelodysplasia (HP:0002863) | 2.18962794 |
| 54 | Rhabdomyosarcoma (HP:0002859) | 2.18824908 |
| 55 | Renal Fanconi syndrome (HP:0001994) | 2.16441856 |
| 56 | Glioma (HP:0009733) | 2.15878047 |
| 57 | Congenital primary aphakia (HP:0007707) | 2.08848080 |
| 58 | Pancreatic cysts (HP:0001737) | 2.08237728 |
| 59 | Medulloblastoma (HP:0002885) | 2.07947589 |
| 60 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.05627308 |
| 61 | Pancreatic fibrosis (HP:0100732) | 2.03903490 |
| 62 | Progressive inability to walk (HP:0002505) | 2.03550803 |
| 63 | Nephrogenic diabetes insipidus (HP:0009806) | 2.03408638 |
| 64 | Clubbing of toes (HP:0100760) | 2.02055419 |
| 65 | Abnormality of glycine metabolism (HP:0010895) | 2.00754792 |
| 66 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.00754792 |
| 67 | Carpal bone hypoplasia (HP:0001498) | 1.98974252 |
| 68 | Microvesicular hepatic steatosis (HP:0001414) | 1.95328393 |
| 69 | True hermaphroditism (HP:0010459) | 1.94293684 |
| 70 | Horseshoe kidney (HP:0000085) | 1.94142485 |
| 71 | Lethargy (HP:0001254) | 1.92534752 |
| 72 | Reduced antithrombin III activity (HP:0001976) | 1.86305346 |
| 73 | Neoplasm of the adrenal cortex (HP:0100641) | 1.84990416 |
| 74 | Respiratory failure (HP:0002878) | 1.84666703 |
| 75 | Postnatal microcephaly (HP:0005484) | 1.84564827 |
| 76 | Gait imbalance (HP:0002141) | 1.84460444 |
| 77 | CNS demyelination (HP:0007305) | 1.84441730 |
| 78 | Pancytopenia (HP:0001876) | 1.83998745 |
| 79 | Degeneration of anterior horn cells (HP:0002398) | 1.78328222 |
| 80 | Abnormality of the anterior horn cell (HP:0006802) | 1.78328222 |
| 81 | Neoplasm of the colon (HP:0100273) | 1.77467141 |
| 82 | Astigmatism (HP:0000483) | 1.77368796 |
| 83 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.76988919 |
| 84 | Ovarian neoplasm (HP:0100615) | 1.76271945 |
| 85 | Hyperglycinuria (HP:0003108) | 1.75911360 |
| 86 | Leukodystrophy (HP:0002415) | 1.75469012 |
| 87 | Abnormality of the carotid arteries (HP:0005344) | 1.75115994 |
| 88 | Respiratory difficulties (HP:0002880) | 1.73044135 |
| 89 | Genital tract atresia (HP:0001827) | 1.71805693 |
| 90 | Abnormality of the renal cortex (HP:0011035) | 1.70566401 |
| 91 | Abnormality of vitamin B metabolism (HP:0004340) | 1.70056133 |
| 92 | Optic disc pallor (HP:0000543) | 1.68005162 |
| 93 | Breast carcinoma (HP:0003002) | 1.67918952 |
| 94 | Abnormality of the pons (HP:0007361) | 1.67202135 |
| 95 | Abnormality of the astrocytes (HP:0100707) | 1.66229433 |
| 96 | Astrocytoma (HP:0009592) | 1.66229433 |
| 97 | Hypomagnesemia (HP:0002917) | 1.66148260 |
| 98 | Abnormal spermatogenesis (HP:0008669) | 1.64671428 |
| 99 | Clitoromegaly (HP:0000057) | 1.61375681 |
| 100 | Hypothermia (HP:0002045) | 1.61119941 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BUB1 | 3.99199975 |
| 2 | EIF2AK3 | 3.39625851 |
| 3 | NEK1 | 3.30319738 |
| 4 | TRIM28 | 3.00581275 |
| 5 | SRPK1 | 2.97763953 |
| 6 | MST4 | 2.95278950 |
| 7 | TSSK6 | 2.91839397 |
| 8 | PBK | 2.82043126 |
| 9 | EIF2AK1 | 2.73019427 |
| 10 | TTK | 2.56616431 |
| 11 | ZAK | 2.47361164 |
| 12 | MAP4K2 | 2.44127151 |
| 13 | PLK3 | 2.26427300 |
| 14 | MKNK2 | 2.23498713 |
| 15 | VRK2 | 2.20494561 |
| 16 | NUAK1 | 2.16123666 |
| 17 | MKNK1 | 2.14720446 |
| 18 | CDC7 | 2.07144151 |
| 19 | PLK4 | 2.03864110 |
| 20 | WEE1 | 1.92256482 |
| 21 | BRSK2 | 1.90608360 |
| 22 | PDK2 | 1.89911124 |
| 23 | BCR | 1.84622118 |
| 24 | STK39 | 1.81854870 |
| 25 | VRK1 | 1.73724274 |
| 26 | FRK | 1.69241332 |
| 27 | TNIK | 1.64676882 |
| 28 | TAF1 | 1.54907997 |
| 29 | WNK3 | 1.54675500 |
| 30 | OXSR1 | 1.52787684 |
| 31 | STK16 | 1.43259836 |
| 32 | BMPR1B | 1.35247320 |
| 33 | PLK1 | 1.32335103 |
| 34 | ACVR1B | 1.30756769 |
| 35 | NME1 | 1.29159638 |
| 36 | ERBB3 | 1.28587157 |
| 37 | WNK4 | 1.18563891 |
| 38 | EIF2AK2 | 1.07219491 |
| 39 | ATR | 1.00615604 |
| 40 | SIK3 | 0.96663875 |
| 41 | CSNK1G1 | 0.94441997 |
| 42 | CSNK1G3 | 0.92029252 |
| 43 | STK38L | 0.90469921 |
| 44 | SCYL2 | 0.88443904 |
| 45 | BCKDK | 0.87625623 |
| 46 | CSNK1A1L | 0.85110068 |
| 47 | BRSK1 | 0.83870374 |
| 48 | STK3 | 0.83067235 |
| 49 | CHEK2 | 0.78249329 |
| 50 | FLT3 | 0.74335854 |
| 51 | PLK2 | 0.73894167 |
| 52 | AURKB | 0.72514926 |
| 53 | CCNB1 | 0.72415230 |
| 54 | GRK1 | 0.72223660 |
| 55 | ATM | 0.71752023 |
| 56 | PNCK | 0.71725886 |
| 57 | CSNK1G2 | 0.69276695 |
| 58 | STK4 | 0.67098646 |
| 59 | RPS6KA4 | 0.66300913 |
| 60 | LATS1 | 0.65057910 |
| 61 | PINK1 | 0.62295203 |
| 62 | CHEK1 | 0.61576440 |
| 63 | STK10 | 0.56633419 |
| 64 | NME2 | 0.51346954 |
| 65 | ADRBK2 | 0.50915488 |
| 66 | MAP3K4 | 0.50617713 |
| 67 | ERBB4 | 0.49981396 |
| 68 | PASK | 0.48454931 |
| 69 | ALK | 0.46645844 |
| 70 | INSRR | 0.43618971 |
| 71 | BRD4 | 0.43529269 |
| 72 | CLK1 | 0.43490710 |
| 73 | CDK7 | 0.42513092 |
| 74 | NEK2 | 0.42208683 |
| 75 | MAPK13 | 0.42054195 |
| 76 | CSNK2A1 | 0.40937314 |
| 77 | CSNK2A2 | 0.38632258 |
| 78 | MAP2K7 | 0.37808621 |
| 79 | FGFR1 | 0.36640487 |
| 80 | MAP3K12 | 0.35697063 |
| 81 | DYRK3 | 0.33868037 |
| 82 | PRKCI | 0.33690285 |
| 83 | MELK | 0.33273059 |
| 84 | MAPKAPK5 | 0.32482251 |
| 85 | PAK3 | 0.30904764 |
| 86 | DYRK2 | 0.30501810 |
| 87 | IRAK1 | 0.29727185 |
| 88 | AURKA | 0.29703922 |
| 89 | PRKCE | 0.29261304 |
| 90 | AKT3 | 0.28506025 |
| 91 | CDK1 | 0.27611326 |
| 92 | NEK6 | 0.27372443 |
| 93 | CDK3 | 0.27202823 |
| 94 | CSNK1E | 0.26318175 |
| 95 | RPS6KA5 | 0.24256497 |
| 96 | DAPK1 | 0.23889694 |
| 97 | NEK9 | 0.23649917 |
| 98 | PRKDC | 0.22984622 |
| 99 | NLK | 0.22745713 |
| 100 | TGFBR1 | 0.22423531 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.04901814 |
| 2 | Non-homologous end-joining_Homo sapiens_hsa03450 | 3.54663920 |
| 3 | Mismatch repair_Homo sapiens_hsa03430 | 3.54570451 |
| 4 | DNA replication_Homo sapiens_hsa03030 | 3.30894786 |
| 5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.18948188 |
| 6 | Homologous recombination_Homo sapiens_hsa03440 | 3.07767065 |
| 7 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.84548943 |
| 8 | Protein export_Homo sapiens_hsa03060 | 2.71855752 |
| 9 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.44190944 |
| 10 | * Nucleotide excision repair_Homo sapiens_hsa03420 | 2.29711953 |
| 11 | RNA polymerase_Homo sapiens_hsa03020 | 2.20176919 |
| 12 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.19977596 |
| 13 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.19017530 |
| 14 | RNA transport_Homo sapiens_hsa03013 | 2.18501323 |
| 15 | * Basal transcription factors_Homo sapiens_hsa03022 | 2.18221207 |
| 16 | Base excision repair_Homo sapiens_hsa03410 | 2.07356724 |
| 17 | RNA degradation_Homo sapiens_hsa03018 | 2.03199596 |
| 18 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.00410157 |
| 19 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.98129549 |
| 20 | Spliceosome_Homo sapiens_hsa03040 | 1.95043836 |
| 21 | Cell cycle_Homo sapiens_hsa04110 | 1.80875074 |
| 22 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.77027696 |
| 23 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.73207123 |
| 24 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.72943123 |
| 25 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.71199693 |
| 26 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.71185276 |
| 27 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.65104775 |
| 28 | Parkinsons disease_Homo sapiens_hsa05012 | 1.60791808 |
| 29 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.56321739 |
| 30 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.54215081 |
| 31 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.52092504 |
| 32 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.46565820 |
| 33 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.37749003 |
| 34 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.25281693 |
| 35 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.24069641 |
| 36 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.21915323 |
| 37 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.19156682 |
| 38 | Purine metabolism_Homo sapiens_hsa00230 | 1.18412129 |
| 39 | Huntingtons disease_Homo sapiens_hsa05016 | 1.14873092 |
| 40 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.13690289 |
| 41 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.04922007 |
| 42 | Carbon metabolism_Homo sapiens_hsa01200 | 1.00804979 |
| 43 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.97321139 |
| 44 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.95272342 |
| 45 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.90041040 |
| 46 | Peroxisome_Homo sapiens_hsa04146 | 0.87816034 |
| 47 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.87796457 |
| 48 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.87734124 |
| 49 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.87218681 |
| 50 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.86975491 |
| 51 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.85884489 |
| 52 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.84560830 |
| 53 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.82567799 |
| 54 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.79622318 |
| 55 | Alzheimers disease_Homo sapiens_hsa05010 | 0.79159359 |
| 56 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.78383194 |
| 57 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.71882057 |
| 58 | Metabolic pathways_Homo sapiens_hsa01100 | 0.69909105 |
| 59 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.65397662 |
| 60 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.58971891 |
| 61 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.53706183 |
| 62 | Ribosome_Homo sapiens_hsa03010 | 0.53598487 |
| 63 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.53117910 |
| 64 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.51592755 |
| 65 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.51339614 |
| 66 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.50815144 |
| 67 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.50023240 |
| 68 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.49539830 |
| 69 | Phototransduction_Homo sapiens_hsa04744 | 0.48734854 |
| 70 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.47109793 |
| 71 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.46762405 |
| 72 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.45214645 |
| 73 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.41332954 |
| 74 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.38341517 |
| 75 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.37991274 |
| 76 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.36687008 |
| 77 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.35847081 |
| 78 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.35038554 |
| 79 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.29841753 |
| 80 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.29571748 |
| 81 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.29540823 |
| 82 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.29307596 |
| 83 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.27533363 |
| 84 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.26076391 |
| 85 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.23468600 |
| 86 | Legionellosis_Homo sapiens_hsa05134 | 0.22692598 |
| 87 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.21437396 |
| 88 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.21159453 |
| 89 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.20504005 |
| 90 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.20428334 |
| 91 | Retinol metabolism_Homo sapiens_hsa00830 | 0.19914294 |
| 92 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.18603128 |
| 93 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.16781693 |
| 94 | Sulfur relay system_Homo sapiens_hsa04122 | 0.15970191 |
| 95 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.15873633 |
| 96 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.11428530 |
| 97 | Lysine degradation_Homo sapiens_hsa00310 | 0.10430306 |
| 98 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.10403078 |
| 99 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.06664005 |
| 100 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.06124183 |

