GTSE1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein localization to kinetochore (GO:0034501)5.22783696
2DNA unwinding involved in DNA replication (GO:0006268)4.79168836
3mitotic sister chromatid segregation (GO:0000070)4.75034002
4mitotic metaphase plate congression (GO:0007080)4.72326758
5nuclear pore organization (GO:0006999)4.63521156
6DNA topological change (GO:0006265)4.63394778
7DNA ligation (GO:0006266)4.62677971
8DNA replication initiation (GO:0006270)4.52156324
9mitotic nuclear envelope disassembly (GO:0007077)4.46473927
10nuclear pore complex assembly (GO:0051292)4.43648725
11protein localization to chromosome, centromeric region (GO:0071459)4.43402266
12chromosome condensation (GO:0030261)4.38137374
13DNA replication-dependent nucleosome organization (GO:0034723)4.35963044
14DNA replication-dependent nucleosome assembly (GO:0006335)4.35963044
15sister chromatid segregation (GO:0000819)4.31320521
16DNA strand elongation involved in DNA replication (GO:0006271)4.30527982
17regulation of posttranscriptional gene silencing (GO:0060147)4.26267019
18regulation of gene silencing by miRNA (GO:0060964)4.26267019
19regulation of gene silencing by RNA (GO:0060966)4.26267019
20membrane disassembly (GO:0030397)4.15897242
21nuclear envelope disassembly (GO:0051081)4.15897242
22folic acid-containing compound biosynthetic process (GO:0009396)4.12183521
23regulation of spindle organization (GO:0090224)4.11531819
24DNA strand elongation (GO:0022616)4.07487905
25metaphase plate congression (GO:0051310)4.04674440
26formation of translation preinitiation complex (GO:0001731)4.03366307
27establishment of integrated proviral latency (GO:0075713)4.02636903
28regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.99351051
29DNA replication checkpoint (GO:0000076)3.97768548
30mitotic chromosome condensation (GO:0007076)3.96169643
31microtubule depolymerization (GO:0007019)3.88514627
32telomere maintenance via semi-conservative replication (GO:0032201)3.86140515
33nucleobase biosynthetic process (GO:0046112)3.84258244
34DNA packaging (GO:0006323)3.79466066
35regulation of mitotic spindle organization (GO:0060236)3.78642911
36IMP biosynthetic process (GO:0006188)3.78159251
37kinetochore organization (GO:0051383)3.77452702
38positive regulation of chromosome segregation (GO:0051984)3.70584297
39establishment of chromosome localization (GO:0051303)3.67802353
40mitotic sister chromatid cohesion (GO:0007064)3.64747131
41attachment of spindle microtubules to kinetochore (GO:0008608)3.63599868
42maturation of SSU-rRNA (GO:0030490)3.57681564
43heterochromatin organization (GO:0070828)3.56497988
44DNA duplex unwinding (GO:0032508)3.55589394
45DNA geometric change (GO:0032392)3.54902488
46somatic hypermutation of immunoglobulin genes (GO:0016446)3.54042388
47somatic diversification of immune receptors via somatic mutation (GO:0002566)3.54042388
48regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.47363005
49telomere maintenance via recombination (GO:0000722)3.42562526
50chromatin remodeling at centromere (GO:0031055)3.42385789
51kinetochore assembly (GO:0051382)3.41426161
52mitotic recombination (GO:0006312)3.41055459
53pore complex assembly (GO:0046931)3.39030047
54ribosome biogenesis (GO:0042254)3.36881874
55purine nucleobase biosynthetic process (GO:0009113)3.35472008
56CENP-A containing nucleosome assembly (GO:0034080)3.34691183
57regulation of chromosome segregation (GO:0051983)3.33849633
58ribosome assembly (GO:0042255)3.33372972
59spindle assembly involved in mitosis (GO:0090307)3.33342324
60positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.31201340
61positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.31201340
62positive regulation of mitotic sister chromatid separation (GO:1901970)3.31201340
63telomere maintenance via telomere lengthening (GO:0010833)3.30981045
64ATP-dependent chromatin remodeling (GO:0043044)3.29817934
65protein localization to chromosome (GO:0034502)3.29468544
66negative regulation of chromosome segregation (GO:0051985)3.28769733
67IMP metabolic process (GO:0046040)3.28346168
68regulation of centrosome cycle (GO:0046605)3.27120528
69DNA replication-independent nucleosome organization (GO:0034724)3.24808762
70DNA replication-independent nucleosome assembly (GO:0006336)3.24808762
71anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.22704385
72establishment of viral latency (GO:0019043)3.22574169
73nuclear envelope organization (GO:0006998)3.21801926
74negative regulation of mitosis (GO:0045839)3.21345338
75spindle checkpoint (GO:0031577)3.21290058
76mitotic cell cycle (GO:0000278)3.20262333
77pre-miRNA processing (GO:0031054)3.19863218
78protein K6-linked ubiquitination (GO:0085020)3.17852111
79meiotic chromosome segregation (GO:0045132)3.16422962
80regulation of histone H3-K9 methylation (GO:0051570)3.15757547
81regulation of translational fidelity (GO:0006450)3.15646594
82negative regulation of mitotic sister chromatid separation (GO:2000816)3.14898973
83negative regulation of mitotic sister chromatid segregation (GO:0033048)3.14898973
84negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.14898973
85negative regulation of sister chromatid segregation (GO:0033046)3.14898973
86regulation of sister chromatid cohesion (GO:0007063)3.13680643
87regulation of telomere maintenance via telomerase (GO:0032210)3.13442760
88spindle assembly checkpoint (GO:0071173)3.13006580
89regulation of helicase activity (GO:0051095)3.12503729
90nucleotide-excision repair, DNA gap filling (GO:0006297)3.11839832
91regulation of mitotic metaphase/anaphase transition (GO:0030071)3.10400744
92chromosome segregation (GO:0007059)3.09864692
93mitotic spindle assembly checkpoint (GO:0007094)3.08858651
94histone-serine phosphorylation (GO:0035404)3.07680197
95regulation of DNA endoreduplication (GO:0032875)3.06668694
96negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.06273719
97ribonucleoprotein complex biogenesis (GO:0022613)3.05647949
98chromatin assembly or disassembly (GO:0006333)3.05643340
99mitotic spindle checkpoint (GO:0071174)3.05506228
100regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.03838007
101ribosomal small subunit biogenesis (GO:0042274)3.02269171
102establishment of mitotic spindle localization (GO:0040001)3.01542906
103negative regulation of histone methylation (GO:0031061)3.00864241
104regulation of sister chromatid segregation (GO:0033045)2.97553301
105regulation of mitotic sister chromatid separation (GO:0010965)2.97553301
106regulation of mitotic sister chromatid segregation (GO:0033047)2.97553301
107mitotic spindle organization (GO:0007052)2.97291248
108DNA conformation change (GO:0071103)2.96752915
109chromatin assembly (GO:0031497)2.94033624
110chromosome organization (GO:0051276)2.93537876
111paraxial mesoderm development (GO:0048339)2.92579104
112histone exchange (GO:0043486)2.91499969
113ribosomal small subunit assembly (GO:0000028)2.91353109
114mitotic nuclear division (GO:0007067)2.90241340
115regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.89628143
116V(D)J recombination (GO:0033151)2.89232708
117regulation of nuclear cell cycle DNA replication (GO:0033262)2.88024878
118spindle organization (GO:0007051)2.87542203
119regulation of translational termination (GO:0006449)2.86892156
120regulation of double-strand break repair via homologous recombination (GO:0010569)2.86184036
121negative regulation of cell division (GO:0051782)2.86089114
122DNA strand renaturation (GO:0000733)2.84558281
123negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.84280070
124regulation of centriole replication (GO:0046599)2.84231685
125microtubule cytoskeleton organization involved in mitosis (GO:1902850)2.82083254
126ventricular cardiac muscle cell development (GO:0055015)2.81917097
127translational initiation (GO:0006413)2.81448909
128positive regulation of SMAD protein import into nucleus (GO:0060391)2.81411990
129negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.78526259
130replication fork processing (GO:0031297)2.78202831
131spindle assembly (GO:0051225)2.77183930

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.65608664
2FOXM1_23109430_ChIP-Seq_U2OS_Human5.18504909
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.02528140
4* E2F4_17652178_ChIP-ChIP_JURKAT_Human3.68371876
5* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.33743108
6EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.27928616
7* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.08113253
8MYC_19030024_ChIP-ChIP_MESCs_Mouse2.69231361
9* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.50881942
10NELFA_20434984_ChIP-Seq_ESCs_Mouse2.31981518
11MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.26343080
12EST1_17652178_ChIP-ChIP_JURKAT_Human2.24944267
13SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.22553750
14EGR1_19374776_ChIP-ChIP_THP-1_Human2.21744234
15KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.17535423
16ETS1_20019798_ChIP-Seq_JURKAT_Human2.16350867
17NANOG_18555785_ChIP-Seq_MESCs_Mouse2.15444001
18POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.15039181
19AR_21909140_ChIP-Seq_LNCAP_Human2.13939084
20XRN2_22483619_ChIP-Seq_HELA_Human2.13276832
21* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.07487735
22CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.05454761
23KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.01131982
24KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.01131982
25KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.01131982
26* CREB1_15753290_ChIP-ChIP_HEK293T_Human2.00250289
27* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.98078904
28KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.97931318
29E2F1_21310950_ChIP-Seq_MCF-7_Human1.92895231
30POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.87493909
31GABP_17652178_ChIP-ChIP_JURKAT_Human1.85808786
32MYCN_18555785_ChIP-Seq_MESCs_Mouse1.84405088
33E2F1_18555785_ChIP-Seq_MESCs_Mouse1.84002261
34* HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.80770981
35STAT3_1855785_ChIP-Seq_MESCs_Mouse1.73177427
36MYC_22102868_ChIP-Seq_BL_Human1.71174737
37NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.68043940
38TCF3_18692474_ChIP-Seq_MEFs_Mouse1.62948982
39VDR_23849224_ChIP-Seq_CD4+_Human1.61749321
40POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.60430607
41DCP1A_22483619_ChIP-Seq_HELA_Human1.59721302
42TTF2_22483619_ChIP-Seq_HELA_Human1.57807268
43SOX2_18555785_ChIP-Seq_MESCs_Mouse1.57304605
44NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.54607282
45NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.51536201
46FOXP3_21729870_ChIP-Seq_TREG_Human1.51406267
47* THAP11_20581084_ChIP-Seq_MESCs_Mouse1.51065537
48GABP_19822575_ChIP-Seq_HepG2_Human1.48951711
49KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.45425669
50ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.45123795
51ZFX_18555785_ChIP-Seq_MESCs_Mouse1.40359265
52KLF4_18555785_ChIP-Seq_MESCs_Mouse1.38135481
53CIITA_25753668_ChIP-Seq_RAJI_Human1.37426251
54KDM5A_27292631_Chip-Seq_BREAST_Human1.36233323
55ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.34805455
56YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.34279715
57CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.33788451
58PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.32974664
59PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.32885987
60TCF3_18692474_ChIP-Seq_MESCs_Mouse1.31715831
61MYC_18940864_ChIP-ChIP_HL60_Human1.31614198
62ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.30042856
63YY1_21170310_ChIP-Seq_MESCs_Mouse1.29817445
64TP63_19390658_ChIP-ChIP_HaCaT_Human1.29360561
65ESR1_15608294_ChIP-ChIP_MCF-7_Human1.29275886
66SALL1_21062744_ChIP-ChIP_HESCs_Human1.25778368
67KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.23211630
68SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.22334928
69TFEB_21752829_ChIP-Seq_HELA_Human1.20907603
70DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.19409666
71ELK1_19687146_ChIP-ChIP_HELA_Human1.19406296
72TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.18570469
73SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.17188305
74NANOG_21062744_ChIP-ChIP_HESCs_Human1.16379559
75SRF_21415370_ChIP-Seq_HL-1_Mouse1.14634456
76SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.14379825
77CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.11865877
78NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.10753498
79* SOX2_18692474_ChIP-Seq_MEFs_Mouse1.10058614
80SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.09808311
81MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.09603430
82HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.08180164
83OCT4_18692474_ChIP-Seq_MEFs_Mouse1.07582011
84* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.07521394
85CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.05801065
86NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.05527385
87ELF1_17652178_ChIP-ChIP_JURKAT_Human1.05403954
88SOX2_16153702_ChIP-ChIP_HESCs_Human1.04164529
89E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.02397386
90SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.01487763
91TP63_17297297_ChIP-ChIP_HaCaT_Human1.00653430
92TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.00014443
93* SOX2_18692474_ChIP-Seq_MESCs_Mouse0.99738312
94E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.99666900
95NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.99396119
96NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.98133364
97VDR_21846776_ChIP-Seq_THP-1_Human0.97975810
98TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.95861476
99HOXB4_20404135_ChIP-ChIP_EML_Mouse0.95574954
100ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.94378601
101POU5F1_16518401_ChIP-PET_MESCs_Mouse0.94288302
102TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.94056498
103* ERG_20887958_ChIP-Seq_HPC-7_Mouse0.93898503
104FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.93179235
105NANOG_16153702_ChIP-ChIP_HESCs_Human0.93138256
106POU5F1_18692474_ChIP-Seq_MESCs_Mouse0.92216469
107* NANOG_18692474_ChIP-Seq_MEFs_Mouse0.90572234
108PADI4_21655091_ChIP-ChIP_MCF-7_Human0.89906221
109CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.89722623
110ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.89549275
111SOX17_20123909_ChIP-Seq_XEN_Mouse0.86550624
112CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.85724993
113PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.80816570
114DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.80370862
115BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.77639253
116POU5F1_16153702_ChIP-ChIP_HESCs_Human0.76894405
117SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.73225952
118NOTCH1_21737748_ChIP-Seq_TLL_Human0.72136389
119CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.69256230
120EWS_26573619_Chip-Seq_HEK293_Human0.67975695
121GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.67241944
122TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.66012163
123CHD1_26751641_Chip-Seq_LNCaP_Human0.63647354
124CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.62294173
125SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.61781684
126FOXP1_21924763_ChIP-Seq_HESCs_Human0.61211388

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.64462312
2MP0003111_abnormal_nucleus_morphology4.54129236
3MP0010094_abnormal_chromosome_stability4.40777007
4MP0004957_abnormal_blastocyst_morpholog4.24632225
5MP0008057_abnormal_DNA_replication3.89918848
6MP0003077_abnormal_cell_cycle3.89893959
7MP0010352_gastrointestinal_tract_polyps2.93667886
8MP0008058_abnormal_DNA_repair2.72488530
9MP0008007_abnormal_cellular_replicative2.63912521
10MP0001730_embryonic_growth_arrest2.62623110
11MP0008932_abnormal_embryonic_tissue2.51834653
12MP0000350_abnormal_cell_proliferation2.46855047
13MP0000566_synostosis2.29076499
14MP0010307_abnormal_tumor_latency2.23734464
15MP0003123_paternal_imprinting2.13560138
16MP0001672_abnormal_embryogenesis/_devel2.07507953
17MP0005380_embryogenesis_phenotype2.07507953
18MP0001697_abnormal_embryo_size1.99095676
19MP0009697_abnormal_copulation1.98583511
20MP0003136_yellow_coat_color1.95145938
21MP0005076_abnormal_cell_differentiation1.94755329
22MP0002085_abnormal_embryonic_tissue1.94098882
23MP0003705_abnormal_hypodermis_morpholog1.93950253
24MP0010030_abnormal_orbit_morphology1.92954304
25MP0002084_abnormal_developmental_patter1.91588826
26MP0003806_abnormal_nucleotide_metabolis1.84129069
27MP0003984_embryonic_growth_retardation1.82165164
28MP0002938_white_spotting1.80453103
29MP0004197_abnormal_fetal_growth/weight/1.78894179
30MP0002088_abnormal_embryonic_growth/wei1.78485603
31MP0002653_abnormal_ependyma_morphology1.77043387
32MP0002086_abnormal_extraembryonic_tissu1.76066673
33MP0004133_heterotaxia1.75082144
34MP0002080_prenatal_lethality1.74325980
35MP0003786_premature_aging1.74144559
36MP0003890_abnormal_embryonic-extraembry1.66904947
37MP0008877_abnormal_DNA_methylation1.66218347
38MP0009379_abnormal_foot_pigmentation1.64473179
39MP0000490_abnormal_crypts_of1.56328670
40MP0002396_abnormal_hematopoietic_system1.46099933
41MP0003119_abnormal_digestive_system1.45943559
42MP0001346_abnormal_lacrimal_gland1.45579580
43MP0003718_maternal_effect1.45333340
44MP0001293_anophthalmia1.40729586
45MP0000313_abnormal_cell_death1.39793582
46MP0003566_abnormal_cell_adhesion1.37837141
47MP0003941_abnormal_skin_development1.34758990
48MP0009053_abnormal_anal_canal1.34727385
49MP0002234_abnormal_pharynx_morphology1.34619886
50MP0002019_abnormal_tumor_incidence1.32548804
51MP0003567_abnormal_fetal_cardiomyocyte1.27832654
52MP0003121_genomic_imprinting1.24822791
53MP0000049_abnormal_middle_ear1.24096813
54MP0005023_abnormal_wound_healing1.23204795
55MP0000537_abnormal_urethra_morphology1.22981344
56MP0001849_ear_inflammation1.21300681
57MP0000372_irregular_coat_pigmentation1.15790218
58MP0008789_abnormal_olfactory_epithelium1.13047813
59MP0002111_abnormal_tail_morphology1.09173175
60MP0002233_abnormal_nose_morphology1.08553997
61MP0002210_abnormal_sex_determination1.07992142
62MP0004808_abnormal_hematopoietic_stem1.07439210
63MP0003283_abnormal_digestive_organ1.03641238
64MP0001915_intracranial_hemorrhage1.02767234
65MP0004264_abnormal_extraembryonic_tissu1.01715475
66MP0001145_abnormal_male_reproductive1.01400160
67MP0003937_abnormal_limbs/digits/tail_de1.00424915
68MP0006035_abnormal_mitochondrial_morpho0.95923304
69MP0001545_abnormal_hematopoietic_system0.95758580
70MP0005397_hematopoietic_system_phenotyp0.95758580
71MP0001529_abnormal_vocalization0.93993045
72MP0009278_abnormal_bone_marrow0.93950355
73MP0000428_abnormal_craniofacial_morphol0.91881874
74MP0005621_abnormal_cell_physiology0.90121938
75MP0000631_abnormal_neuroendocrine_gland0.89002062
76MP0000858_altered_metastatic_potential0.88459870
77MP0009250_abnormal_appendicular_skeleto0.88366996
78MP0005384_cellular_phenotype0.87307984
79MP0003385_abnormal_body_wall0.86960849
80MP0002092_abnormal_eye_morphology0.86093600
81MP0003315_abnormal_perineum_morphology0.85554402
82MP0003942_abnormal_urinary_system0.83584733
83MP0000733_abnormal_muscle_development0.83543040
84MP0002697_abnormal_eye_size0.83274433
85MP0005171_absent_coat_pigmentation0.82861577
86MP0000358_abnormal_cell_content/0.82834664
87MP0000432_abnormal_head_morphology0.82486977
88MP0001286_abnormal_eye_development0.82263729
89MP0005501_abnormal_skin_physiology0.81788994
90MP0001929_abnormal_gametogenesis0.81149115
91MP0002163_abnormal_gland_morphology0.80908321
92MP0000653_abnormal_sex_gland0.80719842
93MP0005394_taste/olfaction_phenotype0.79451919
94MP0005499_abnormal_olfactory_system0.79451919
95MP0009333_abnormal_splenocyte_physiolog0.77564042
96MP0006292_abnormal_olfactory_placode0.77456388
97MP0000703_abnormal_thymus_morphology0.77247465
98MP0000647_abnormal_sebaceous_gland0.77231085
99MP0005623_abnormal_meninges_morphology0.77009433
100MP0009703_decreased_birth_body0.76736165
101MP0000762_abnormal_tongue_morphology0.76288611
102MP0002925_abnormal_cardiovascular_devel0.75660958
103MP0002877_abnormal_melanocyte_morpholog0.75377088
104MP0003698_abnormal_male_reproductive0.74346204
105MP0002249_abnormal_larynx_morphology0.73760785
106MP0003938_abnormal_ear_development0.73446841
107MP0002116_abnormal_craniofacial_bone0.72761436
108MP0002095_abnormal_skin_pigmentation0.72391366
109MP0009672_abnormal_birth_weight0.72295367
110MP0000477_abnormal_intestine_morphology0.72208474
111MP0004233_abnormal_muscle_weight0.71463998
112MP0003861_abnormal_nervous_system0.70919624
113MP0005408_hypopigmentation0.70820023
114MP0002161_abnormal_fertility/fecundity0.70717846
115MP0003699_abnormal_female_reproductive0.69958302
116MP0002177_abnormal_outer_ear0.69068851
117MP0003935_abnormal_craniofacial_develop0.68375706
118MP0002160_abnormal_reproductive_system0.68150180
119MP0003943_abnormal_hepatobiliary_system0.67872421
120MP0008770_decreased_survivor_rate0.67741266
121MP0005391_vision/eye_phenotype0.67365242
122MP0003755_abnormal_palate_morphology0.67248376
123MP0003115_abnormal_respiratory_system0.66199086
124MP0005266_abnormal_metabolism0.65492567
125MP0010234_abnormal_vibrissa_follicle0.64615000
126MP0002114_abnormal_axial_skeleton0.63217514
127MP0002722_abnormal_immune_system0.63133757
128MP0001119_abnormal_female_reproductive0.62227494
129MP0005395_other_phenotype0.61267776
130MP0003950_abnormal_plasma_membrane0.59817055
131MP0002932_abnormal_joint_morphology0.59800137
132MP0003936_abnormal_reproductive_system0.59732190
133MP0000516_abnormal_urinary_system0.58978346
134MP0005367_renal/urinary_system_phenotyp0.58978346
135MP0000750_abnormal_muscle_regeneration0.58660010
136MP0003453_abnormal_keratinocyte_physiol0.57885814
137MP0003448_altered_tumor_morphology0.57803994

Predicted human phenotypes

RankGene SetZ-score
1Ependymoma (HP:0002888)4.36586902
2Birth length less than 3rd percentile (HP:0003561)3.97945203
3Selective tooth agenesis (HP:0001592)3.78682556
4Chromsome breakage (HP:0040012)3.67348369
5Breast hypoplasia (HP:0003187)3.64563071
6Aplasia/Hypoplasia of the sacrum (HP:0008517)3.61186355
7Chromosomal breakage induced by crosslinking agents (HP:0003221)3.59311260
8Abnormality of the labia minora (HP:0012880)3.44333978
9Medulloblastoma (HP:0002885)3.38956775
10Absent radius (HP:0003974)3.34927045
11Patellar aplasia (HP:0006443)3.33962790
12Reticulocytopenia (HP:0001896)3.30633617
13Astrocytoma (HP:0009592)3.17301635
14Abnormality of the astrocytes (HP:0100707)3.17301635
15Colon cancer (HP:0003003)3.16803288
16Aplasia involving forearm bones (HP:0009822)3.13813963
17Absent forearm bone (HP:0003953)3.13813963
18Aplasia/Hypoplasia of the patella (HP:0006498)3.10552681
19Rhabdomyosarcoma (HP:0002859)2.99940604
20Carpal bone hypoplasia (HP:0001498)2.96091784
21Supernumerary spleens (HP:0009799)2.86549816
22Abdominal situs inversus (HP:0003363)2.85656984
23Abnormality of abdominal situs (HP:0011620)2.85656984
24Agnosia (HP:0010524)2.85639861
25Impulsivity (HP:0100710)2.85352062
26Aplasia/hypoplasia of the humerus (HP:0006507)2.84812810
27Meckel diverticulum (HP:0002245)2.84008410
28Degeneration of anterior horn cells (HP:0002398)2.78969919
29Abnormality of the anterior horn cell (HP:0006802)2.78969919
30Absent thumb (HP:0009777)2.78473388
31Rib fusion (HP:0000902)2.77455503
32Abnormality of the ileum (HP:0001549)2.76739060
33Cortical dysplasia (HP:0002539)2.72973047
34Abnormality of chromosome stability (HP:0003220)2.71877039
35Neoplasm of the oral cavity (HP:0100649)2.67562420
36Aplasia/Hypoplasia of the uvula (HP:0010293)2.67471242
37Missing ribs (HP:0000921)2.66826953
38Glioma (HP:0009733)2.66204118
39Short humerus (HP:0005792)2.62718433
40Oral leukoplakia (HP:0002745)2.60107597
41Abnormal number of incisors (HP:0011064)2.56874914
42Trismus (HP:0000211)2.56537246
43Broad distal phalanx of finger (HP:0009836)2.55821885
44Deviation of the thumb (HP:0009603)2.55496881
45Abnormality of the preputium (HP:0100587)2.54874756
46Basal cell carcinoma (HP:0002671)2.54209741
47Proximal placement of thumb (HP:0009623)2.51707540
48Duplication of thumb phalanx (HP:0009942)2.50862821
49Neoplasm of striated muscle (HP:0009728)2.47696110
50Duodenal stenosis (HP:0100867)2.47027358
51Small intestinal stenosis (HP:0012848)2.47027358
52Neoplasm of the pancreas (HP:0002894)2.41716358
53Rough bone trabeculation (HP:0100670)2.40709252
54Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.38013429
55Embryonal renal neoplasm (HP:0011794)2.37846067
56Microvesicular hepatic steatosis (HP:0001414)2.32700114
57Facial hemangioma (HP:0000329)2.30202584
58Abnormality of cells of the erythroid lineage (HP:0012130)2.29098916
59Increased nuchal translucency (HP:0010880)2.26160615
60Myelodysplasia (HP:0002863)2.25794017
61Hypoplastic pelvis (HP:0008839)2.24985704
62Septo-optic dysplasia (HP:0100842)2.21719335
63Ectopic kidney (HP:0000086)2.20856582
64Tracheoesophageal fistula (HP:0002575)2.19285832
65Squamous cell carcinoma (HP:0002860)2.16357530
6611 pairs of ribs (HP:0000878)2.15889540
67Abnormality of the duodenum (HP:0002246)2.15651010
68Atresia of the external auditory canal (HP:0000413)2.15372930
69Cafe-au-lait spot (HP:0000957)2.11931565
70Sloping forehead (HP:0000340)2.11301080
71Esophageal atresia (HP:0002032)2.04893654
72Abnormal number of erythroid precursors (HP:0012131)2.04758041
73Horseshoe kidney (HP:0000085)2.04204577
74Multiple enchondromatosis (HP:0005701)2.04198931
75Hypoplasia of the capital femoral epiphysis (HP:0003090)2.02757392
76Premature ovarian failure (HP:0008209)2.01580085
77Abnormal lung lobation (HP:0002101)2.00885735
78Shawl scrotum (HP:0000049)2.00029679
79Clubbing of toes (HP:0100760)1.99584106
80Short thumb (HP:0009778)1.98799334
81Duplicated collecting system (HP:0000081)1.97970085
82Malignant gastrointestinal tract tumors (HP:0006749)1.96826781
83Gastrointestinal carcinoma (HP:0002672)1.96826781
84Biliary tract neoplasm (HP:0100574)1.96292955
85Premature graying of hair (HP:0002216)1.96264461
86Spinal muscular atrophy (HP:0007269)1.94685753
87Bone marrow hypocellularity (HP:0005528)1.93964996
88Cerebral hypomyelination (HP:0006808)1.93867893
89Absent septum pellucidum (HP:0001331)1.93380230
90Fused cervical vertebrae (HP:0002949)1.91855618
91Aplasia/Hypoplasia of the sternum (HP:0006714)1.91444864
92Absent epiphyses (HP:0010577)1.90387542
93Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.90387542
94Hypoplasia of the pons (HP:0012110)1.90073200
95Abnormality of chromosome segregation (HP:0002916)1.89062966
96Partial duplication of the phalanx of hand (HP:0009999)1.88115109
97Triphalangeal thumb (HP:0001199)1.87462318
98Rectovaginal fistula (HP:0000143)1.87097652
99Rectal fistula (HP:0100590)1.87097652
100Oligodactyly (HP:0012165)1.86560486
101Angiofibromas (HP:0010615)1.86488224
102Adenoma sebaceum (HP:0009720)1.86488224
103Overlapping toe (HP:0001845)1.84466968
104Facial cleft (HP:0002006)1.84424900
105High anterior hairline (HP:0009890)1.81895297
106Abnormality of the carotid arteries (HP:0005344)1.81177982
107Abnormality of cochlea (HP:0000375)1.80866061
108Macrocytic anemia (HP:0001972)1.80631503
109Morphological abnormality of the inner ear (HP:0011390)1.80588387
110Pendular nystagmus (HP:0012043)1.79839609
111Abnormality of the calcaneus (HP:0008364)1.79592359
112Arteriovenous malformation (HP:0100026)1.79542528
113High pitched voice (HP:0001620)1.79158958
114Choanal atresia (HP:0000453)1.78579982
115Short 4th metacarpal (HP:0010044)1.78438662
116Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.78438662
117Abnormality of the septum pellucidum (HP:0007375)1.78322635
118Amaurosis fugax (HP:0100576)1.78265424
119Neoplasm of the colon (HP:0100273)1.78068702
120Abnormality of the phalanges of the hallux (HP:0010057)1.77380639
121Atrophy/Degeneration involving motor neurons (HP:0007373)1.76872835
122Volvulus (HP:0002580)1.76616633
123Prominent nose (HP:0000448)1.76510719
124Acute necrotizing encephalopathy (HP:0006965)1.76407948
125Partial duplication of thumb phalanx (HP:0009944)1.76201201
126Holoprosencephaly (HP:0001360)1.75645855
127Nephroblastoma (Wilms tumor) (HP:0002667)1.75578090
128Vertebral fusion (HP:0002948)1.74903984
129Cleft eyelid (HP:0000625)1.74282095
130Breast aplasia (HP:0100783)1.74136006
131Abnormality of the pons (HP:0007361)1.73901431
132Abnormality of pyrimidine metabolism (HP:0004353)1.73885226
133Progressive muscle weakness (HP:0003323)1.72919861
134Hemivertebrae (HP:0002937)1.71531923
135Abnormal mitochondria in muscle tissue (HP:0008316)1.71430619
136Abnormality of DNA repair (HP:0003254)1.71069976
137Preaxial hand polydactyly (HP:0001177)1.70482629
138Abnormality of the renal collecting system (HP:0004742)1.68071229
139Embryonal neoplasm (HP:0002898)1.67941961
140Oligodactyly (hands) (HP:0001180)1.67759210
141Increased hepatocellular lipid droplets (HP:0006565)1.66086372
142Anophthalmia (HP:0000528)1.61912734
143Irregular epiphyses (HP:0010582)1.61675747
144Capillary hemangiomas (HP:0005306)1.60640564
145Abnormality of the proximal phalanges of the hand (HP:0009834)1.60396785

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.63198584
2CDC74.03792323
3WEE13.97040104
4CDK123.52259698
5VRK23.45868646
6NEK23.00701651
7EPHA22.92537320
8TTK2.85799500
9NEK12.77512295
10RPS6KB22.18003132
11* PLK12.06051087
12EIF2AK12.05217215
13TESK22.03853064
14EEF2K2.02751048
15CDK71.94971783
16TSSK61.88685428
17TAF11.82128584
18STK101.78922505
19BRSK21.77410784
20AURKB1.70513332
21CHEK21.61917469
22PLK41.60305421
23SRPK11.59259281
24PASK1.57729889
25MAP3K81.55665872
26MAP3K101.54222243
27SMG11.53109374
28ATR1.52495622
29STK161.45587714
30PLK31.45249129
31CDK41.43476960
32AURKA1.41742010
33PAK41.38887646
34ACVR1B1.38477156
35CHEK11.38256567
36LATS21.35122273
37TLK11.34797312
38BRSK11.27495058
39STK41.25630627
40SCYL21.21632733
41DYRK31.21579736
42BRD41.18616690
43NME21.18091943
44MKNK11.13824213
45NUAK11.12727761
46CDK81.07705340
47ALK1.04453547
48PKN21.02157960
49RPS6KA41.01342215
50CDK61.00754699
51MAPKAPK31.00138365
52VRK10.98176987
53PIM10.97456347
54CDK20.97382279
55TESK10.95896419
56ATM0.92980007
57NME10.92250051
58TGFBR10.88261992
59MTOR0.86542144
60EIF2AK30.85819074
61MELK0.81437199
62PAK10.80364542
63STK38L0.77840897
64ICK0.77076890
65MKNK20.77039211
66PRKCI0.76979024
67STK30.75092357
68FLT30.74028665
69LATS10.71131934
70CDK10.70502804
71PNCK0.67629139
72ZAK0.67486988
73LRRK20.64491719
74CLK10.61377812
75BMX0.60298947
76CSNK2A20.58958459
77AKT20.54108430
78TTN0.54092111
79UHMK10.54087826
80TRIM280.53310274
81PAK20.53116868
82MET0.51558896
83MAP3K110.51174753
84AKT30.50473144
85CSNK2A10.48911261
86CCNB10.48824998
87GRK60.47974573
88PIM20.47039239
89MST40.45169914
90DDR20.42095571
91ERBB40.40906739
92CSNK1D0.40592382
93CDK150.40513951
94* CSNK1E0.40326146
95CDK180.39285975
96PRKDC0.39098682
97CDK90.38829168
98MST1R0.37959274
99TNIK0.37213194
100BRAF0.36710874
101TRIB30.36599705
102WNK40.35472568
103CSNK1G10.35267858
104BMPR1B0.33506418
105LIMK10.32911429
106MAPK140.32307860
107FGFR10.32126604
108EPHB20.32108396
109CAMK1G0.31783749
110PBK0.31163023
111CDK140.30379411
112RPS6KA50.30263311
113PDGFRA0.30127654
114CDK30.28046585
115* MAPK10.27525707
116AKT10.27323028
117TAOK20.26219425
118CDK11A0.25199950
119MAP2K30.24996963
120TYRO30.24123543
121MARK30.24108340
122MAP3K90.24050088
123EIF2AK20.23572098
124MAPKAPK20.23458588
125DYRK20.23334974
126IRAK30.22622858
127FGFR20.22533319
128CSNK1G30.22374147
129MAPK110.21129629
130MAPKAPK50.19310139
131KDR0.19006087

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.79591727
2Mismatch repair_Homo sapiens_hsa034304.37302811
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.70745607
4RNA transport_Homo sapiens_hsa030133.35424141
5Spliceosome_Homo sapiens_hsa030403.27088135
6One carbon pool by folate_Homo sapiens_hsa006703.14372370
7Cell cycle_Homo sapiens_hsa041103.04481918
8Base excision repair_Homo sapiens_hsa034103.00158023
9Homologous recombination_Homo sapiens_hsa034402.87859278
10Nucleotide excision repair_Homo sapiens_hsa034202.84002724
11Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.70405845
12Ribosome_Homo sapiens_hsa030102.66976297
13RNA polymerase_Homo sapiens_hsa030202.59166408
14Fanconi anemia pathway_Homo sapiens_hsa034602.35823813
15Proteasome_Homo sapiens_hsa030502.20353089
16* p53 signaling pathway_Homo sapiens_hsa041152.00984962
17mRNA surveillance pathway_Homo sapiens_hsa030152.00109243
18Pyrimidine metabolism_Homo sapiens_hsa002401.98955793
19Non-homologous end-joining_Homo sapiens_hsa034501.98954481
20RNA degradation_Homo sapiens_hsa030181.76922251
21Basal transcription factors_Homo sapiens_hsa030221.69351782
22Parkinsons disease_Homo sapiens_hsa050121.41261578
23Oxidative phosphorylation_Homo sapiens_hsa001901.40357099
24Protein export_Homo sapiens_hsa030601.38474071
25Huntingtons disease_Homo sapiens_hsa050161.36569726
26Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.35284353
27Systemic lupus erythematosus_Homo sapiens_hsa053221.26742228
28Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.25699905
29Viral carcinogenesis_Homo sapiens_hsa052031.20920179
30Oocyte meiosis_Homo sapiens_hsa041141.17064919
31Biosynthesis of amino acids_Homo sapiens_hsa012301.14698221
32Epstein-Barr virus infection_Homo sapiens_hsa051691.14596319
33MicroRNAs in cancer_Homo sapiens_hsa052061.08321383
34Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.05357384
35Hippo signaling pathway_Homo sapiens_hsa043901.00343185
36Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.00180615
37Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.94049240
38Basal cell carcinoma_Homo sapiens_hsa052170.92407420
39HTLV-I infection_Homo sapiens_hsa051660.92106719
40Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.91997363
41Purine metabolism_Homo sapiens_hsa002300.91082990
42Small cell lung cancer_Homo sapiens_hsa052220.88309072
43Pyruvate metabolism_Homo sapiens_hsa006200.88278364
44Selenocompound metabolism_Homo sapiens_hsa004500.88109711
45Cyanoamino acid metabolism_Homo sapiens_hsa004600.87410421
46Bladder cancer_Homo sapiens_hsa052190.87064666
47Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.83955934
48Steroid biosynthesis_Homo sapiens_hsa001000.81827860
49Cysteine and methionine metabolism_Homo sapiens_hsa002700.78141395
50Herpes simplex infection_Homo sapiens_hsa051680.77892931
51TGF-beta signaling pathway_Homo sapiens_hsa043500.77538144
52Thyroid cancer_Homo sapiens_hsa052160.77040168
53Pentose phosphate pathway_Homo sapiens_hsa000300.74451836
54Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.73874841
55Alzheimers disease_Homo sapiens_hsa050100.72509321
56Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.71405214
57Hedgehog signaling pathway_Homo sapiens_hsa043400.69665816
58Adherens junction_Homo sapiens_hsa045200.69004214
59Antigen processing and presentation_Homo sapiens_hsa046120.68200010
602-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.67683916
61Notch signaling pathway_Homo sapiens_hsa043300.67550232
62N-Glycan biosynthesis_Homo sapiens_hsa005100.63121107
63Folate biosynthesis_Homo sapiens_hsa007900.62694608
64Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.62561794
65mTOR signaling pathway_Homo sapiens_hsa041500.59925178
66Colorectal cancer_Homo sapiens_hsa052100.58885819
67Transcriptional misregulation in cancer_Homo sapiens_hsa052020.57933406
68Apoptosis_Homo sapiens_hsa042100.57362357
69Vitamin B6 metabolism_Homo sapiens_hsa007500.55883092
70Chronic myeloid leukemia_Homo sapiens_hsa052200.52635581
71Central carbon metabolism in cancer_Homo sapiens_hsa052300.52626669
72Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.52451132
73Fructose and mannose metabolism_Homo sapiens_hsa000510.52391899
74Carbon metabolism_Homo sapiens_hsa012000.51717482
75Fatty acid elongation_Homo sapiens_hsa000620.50738852
76Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.48698968
77Drug metabolism - other enzymes_Homo sapiens_hsa009830.48565145
78Glutathione metabolism_Homo sapiens_hsa004800.47473140
79Tight junction_Homo sapiens_hsa045300.46522933
80Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.45387350
81Legionellosis_Homo sapiens_hsa051340.44893934
82Pathways in cancer_Homo sapiens_hsa052000.44523544
83Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.43595461
84HIF-1 signaling pathway_Homo sapiens_hsa040660.41936523
85Metabolic pathways_Homo sapiens_hsa011000.41667560
86Alcoholism_Homo sapiens_hsa050340.41502563
87Shigellosis_Homo sapiens_hsa051310.41279362
88Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.39731095
89Proteoglycans in cancer_Homo sapiens_hsa052050.39650850
90Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.39376467
91Propanoate metabolism_Homo sapiens_hsa006400.37226999
92Lysine degradation_Homo sapiens_hsa003100.35615894
93Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.34892670
94Melanoma_Homo sapiens_hsa052180.33969984
95Prostate cancer_Homo sapiens_hsa052150.33706862
96Sulfur relay system_Homo sapiens_hsa041220.33382664
97Hepatitis B_Homo sapiens_hsa051610.33309142
98Wnt signaling pathway_Homo sapiens_hsa043100.31313821
99Viral myocarditis_Homo sapiens_hsa054160.28675760
100Cardiac muscle contraction_Homo sapiens_hsa042600.27983101
101Galactose metabolism_Homo sapiens_hsa000520.27401204
102Regulation of actin cytoskeleton_Homo sapiens_hsa048100.26443460
103Acute myeloid leukemia_Homo sapiens_hsa052210.24072546
104Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.23823561
105Non-small cell lung cancer_Homo sapiens_hsa052230.23155050
106PI3K-Akt signaling pathway_Homo sapiens_hsa041510.22842060
107Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.22814641
108Thyroid hormone signaling pathway_Homo sapiens_hsa049190.20421208
109Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.20261444
110Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.18921552
111Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.18701353
112Endometrial cancer_Homo sapiens_hsa052130.18252214
113Leukocyte transendothelial migration_Homo sapiens_hsa046700.16661617
114FoxO signaling pathway_Homo sapiens_hsa040680.16128281
115Pancreatic cancer_Homo sapiens_hsa052120.16024828
116Focal adhesion_Homo sapiens_hsa045100.15144657
117Renin-angiotensin system_Homo sapiens_hsa046140.13377469
118Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.12726254
119Arginine and proline metabolism_Homo sapiens_hsa003300.12414111
120Measles_Homo sapiens_hsa051620.12075769
121Vitamin digestion and absorption_Homo sapiens_hsa049770.11385829
122Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.11258244
123Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.10893216
124Melanogenesis_Homo sapiens_hsa049160.10721791
125Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.09388298
126Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.08416982
127Fatty acid metabolism_Homo sapiens_hsa012120.07672101

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