

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 6.43305644 |
| 2 | cardiac muscle contraction (GO:0060048) | 6.42576733 |
| 3 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 6.33098500 |
| 4 | cardiac myofibril assembly (GO:0055003) | 5.85614774 |
| 5 | neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976) | 5.80375822 |
| 6 | sarcomere organization (GO:0045214) | 5.72716229 |
| 7 | regulation of cell communication by electrical coupling (GO:0010649) | 5.69024903 |
| 8 | actin-myosin filament sliding (GO:0033275) | 5.30622102 |
| 9 | muscle filament sliding (GO:0030049) | 5.30622102 |
| 10 | regulation of relaxation of muscle (GO:1901077) | 5.28142990 |
| 11 | regulation of actin filament-based movement (GO:1903115) | 5.24398664 |
| 12 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 5.10316806 |
| 13 | myofibril assembly (GO:0030239) | 5.07451810 |
| 14 | heart contraction (GO:0060047) | 4.98393866 |
| 15 | heart process (GO:0003015) | 4.98393866 |
| 16 | ventricular cardiac muscle tissue morphogenesis (GO:0055010) | 4.87241475 |
| 17 | regulation of the force of heart contraction (GO:0002026) | 4.64955156 |
| 18 | cardiac muscle tissue morphogenesis (GO:0055008) | 4.60830188 |
| 19 | relaxation of cardiac muscle (GO:0055119) | 4.59149552 |
| 20 | striated muscle contraction (GO:0006941) | 4.53625852 |
| 21 | protein-chromophore linkage (GO:0018298) | 4.50982288 |
| 22 | actin-mediated cell contraction (GO:0070252) | 4.50135770 |
| 23 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 4.44114485 |
| 24 | cobalamin metabolic process (GO:0009235) | 4.42378312 |
| 25 | cell communication involved in cardiac conduction (GO:0086065) | 4.37902249 |
| 26 | regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 4.34378646 |
| 27 | cardiac muscle hypertrophy (GO:0003300) | 4.31360143 |
| 28 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 4.31346349 |
| 29 | positive regulation of inositol phosphate biosynthetic process (GO:0060732) | 4.24587700 |
| 30 | positive regulation of calcium ion transmembrane transporter activity (GO:1901021) | 4.13799782 |
| 31 | regulation of striated muscle contraction (GO:0006942) | 4.13462998 |
| 32 | striated muscle hypertrophy (GO:0014897) | 4.11043068 |
| 33 | detection of calcium ion (GO:0005513) | 4.08020175 |
| 34 | muscle tissue morphogenesis (GO:0060415) | 4.06439688 |
| 35 | actomyosin structure organization (GO:0031032) | 4.04667401 |
| 36 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 4.00760332 |
| 37 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 3.97851295 |
| 38 | peptidyl-proline hydroxylation (GO:0019511) | 3.97291026 |
| 39 | cardiac muscle cell development (GO:0055013) | 3.96739839 |
| 40 | adult heart development (GO:0007512) | 3.96490912 |
| 41 | positive regulation of prostaglandin secretion (GO:0032308) | 3.83864843 |
| 42 | regulation of cardiac muscle contraction (GO:0055117) | 3.81955638 |
| 43 | regulation of cardioblast differentiation (GO:0051890) | 3.81263980 |
| 44 | cardiac cell development (GO:0055006) | 3.76822583 |
| 45 | positive regulation of transcription initiation from RNA polymerase II promoter (GO:0060261) | 3.69406546 |
| 46 | ventricular cardiac muscle cell action potential (GO:0086005) | 3.67573428 |
| 47 | muscle hypertrophy (GO:0014896) | 3.63297051 |
| 48 | regulation of cardiac muscle cell contraction (GO:0086004) | 3.57196338 |
| 49 | L-methionine salvage (GO:0071267) | 3.55342215 |
| 50 | L-methionine biosynthetic process (GO:0071265) | 3.55342215 |
| 51 | amino acid salvage (GO:0043102) | 3.55342215 |
| 52 | cell communication by electrical coupling (GO:0010644) | 3.54586887 |
| 53 | ventricular cardiac muscle cell development (GO:0055015) | 3.52606582 |
| 54 | heart trabecula formation (GO:0060347) | 3.51691346 |
| 55 | regulation of ATP catabolic process (GO:1903289) | 3.50024036 |
| 56 | regulation of ATPase activity (GO:0043462) | 3.50024036 |
| 57 | regulation of heart rate (GO:0002027) | 3.49726418 |
| 58 | carnitine shuttle (GO:0006853) | 3.49097652 |
| 59 | digestion (GO:0007586) | 3.45128303 |
| 60 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 3.37857773 |
| 61 | positive regulation of heart rate (GO:0010460) | 3.34612977 |
| 62 | nephron tubule development (GO:0072080) | 3.33780438 |
| 63 | regulation of heart contraction (GO:0008016) | 3.31764900 |
| 64 | nephron tubule formation (GO:0072079) | 3.31325629 |
| 65 | protein hydroxylation (GO:0018126) | 3.29956851 |
| 66 | response to redox state (GO:0051775) | 3.24616263 |
| 67 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 3.24155245 |
| 68 | positive regulation of uterine smooth muscle contraction (GO:0070474) | 3.23927175 |
| 69 | fatty acid transmembrane transport (GO:1902001) | 3.23126319 |
| 70 | positive regulation of epidermal growth factor-activated receptor activity (GO:0045741) | 3.21434116 |
| 71 | positive regulation of epidermal growth factor receptor signaling pathway (GO:0045742) | 3.20752146 |
| 72 | regulation of prostaglandin secretion (GO:0032306) | 3.18071430 |
| 73 | methionine biosynthetic process (GO:0009086) | 3.16043667 |
| 74 | actin filament-based movement (GO:0030048) | 3.15969475 |
| 75 | regulation of muscle contraction (GO:0006937) | 3.12115083 |
| 76 | regulation of membrane repolarization (GO:0060306) | 3.11031384 |
| 77 | positive regulation of DNA-templated transcription, initiation (GO:2000144) | 3.09157804 |
| 78 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 3.08008857 |
| 79 | intestinal cholesterol absorption (GO:0030299) | 3.07828064 |
| 80 | negative regulation of metanephros development (GO:0072217) | 3.06698791 |
| 81 | otic vesicle formation (GO:0030916) | 3.03817959 |
| 82 | response to stimulus involved in regulation of muscle adaptation (GO:0014874) | 3.03086296 |
| 83 | regulation of calcium ion transmembrane transporter activity (GO:1901019) | 3.01853038 |
| 84 | regulation of calcium ion transmembrane transport (GO:1903169) | 3.01853038 |
| 85 | positive regulation of ERBB signaling pathway (GO:1901186) | 3.01699345 |
| 86 | nephron tubule morphogenesis (GO:0072078) | 3.00236608 |
| 87 | nephron epithelium morphogenesis (GO:0072088) | 3.00236608 |
| 88 | cardiac muscle hypertrophy in response to stress (GO:0014898) | 2.98555610 |
| 89 | muscle hypertrophy in response to stress (GO:0003299) | 2.98555610 |
| 90 | cardiac muscle adaptation (GO:0014887) | 2.98555610 |
| 91 | regulation of inositol phosphate biosynthetic process (GO:0010919) | 2.97337603 |
| 92 | negative regulation of mesenchymal cell apoptotic process (GO:2001054) | 2.91638815 |
| 93 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.91284853 |
| 94 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 2.90309409 |
| 95 | renal tubule development (GO:0061326) | 2.88311432 |
| 96 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.86019722 |
| 97 | detection of light stimulus involved in visual perception (GO:0050908) | 2.86019722 |
| 98 | regulation of muscle system process (GO:0090257) | 2.85798717 |
| 99 | regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:1902235 | 2.84920154 |
| 100 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.84077380 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.51536172 |
| 2 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 3.11738688 |
| 3 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 2.83461963 |
| 4 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 2.66781653 |
| 5 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.52216736 |
| 6 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.50428146 |
| 7 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.38013460 |
| 8 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.32414281 |
| 9 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.05825701 |
| 10 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.99366830 |
| 11 | * CJUN_26792858_Chip-Seq_BT549_Human | 1.95868329 |
| 12 | * SMAD4_21799915_ChIP-Seq_A2780_Human | 1.94743482 |
| 13 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.88955561 |
| 14 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.83467007 |
| 15 | * TP53_18474530_ChIP-ChIP_U2OS_Human | 1.80800081 |
| 16 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.80394998 |
| 17 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.78276242 |
| 18 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.78158362 |
| 19 | TP53_16413492_ChIP-PET_HCT116_Human | 1.72239287 |
| 20 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.70339054 |
| 21 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.67588371 |
| 22 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.67588371 |
| 23 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.66119474 |
| 24 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.63393263 |
| 25 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.62587213 |
| 26 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 1.57019368 |
| 27 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.51243551 |
| 28 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.50171660 |
| 29 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.49920083 |
| 30 | GATA1_22025678_ChIP-Seq_K562_Human | 1.49022048 |
| 31 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 1.48143594 |
| 32 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.47831193 |
| 33 | NFYB_21822215_ChIP-Seq_K562_Human | 1.46930582 |
| 34 | TBL1_22424771_ChIP-Seq_293T_Human | 1.46529910 |
| 35 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.44798504 |
| 36 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.44580947 |
| 37 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 1.43450777 |
| 38 | PHF8_20622853_ChIP-Seq_HELA_Human | 1.42406728 |
| 39 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.37351647 |
| 40 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.36552688 |
| 41 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.35435680 |
| 42 | * P300_19829295_ChIP-Seq_ESCs_Human | 1.34190344 |
| 43 | CBX2_22325352_ChIP-Seq_293T-Rex_Human | 1.33573295 |
| 44 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 1.31358942 |
| 45 | ETV1_20927104_ChIP-Seq_GIST48_Human | 1.31141838 |
| 46 | STAT3_23295773_ChIP-Seq_U87_Human | 1.30775446 |
| 47 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.30708596 |
| 48 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.30393235 |
| 49 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.29758563 |
| 50 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.29758563 |
| 51 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.29026574 |
| 52 | NFYA_21822215_ChIP-Seq_K562_Human | 1.26265618 |
| 53 | VDR_22108803_ChIP-Seq_LS180_Human | 1.25163855 |
| 54 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.24410046 |
| 55 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.23315892 |
| 56 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.21952475 |
| 57 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.21952475 |
| 58 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.19957808 |
| 59 | TCF4_23295773_ChIP-Seq_U87_Human | 1.19870183 |
| 60 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.18916909 |
| 61 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.16382191 |
| 62 | GATA4_21415370_ChIP-Seq_HL-1_Mouse | 1.15125538 |
| 63 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.14225003 |
| 64 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.13991926 |
| 65 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.13323662 |
| 66 | RBPJ_21746931_ChIP-Seq_IB4_Human | 1.12662003 |
| 67 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.12391724 |
| 68 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.11828176 |
| 69 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.09552353 |
| 70 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.09137472 |
| 71 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.09038701 |
| 72 | * NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.08816495 |
| 73 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.08597767 |
| 74 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.08527090 |
| 75 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.07996184 |
| 76 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.07783661 |
| 77 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.07289031 |
| 78 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.06463694 |
| 79 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.05844676 |
| 80 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.05268724 |
| 81 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.04432492 |
| 82 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.04263569 |
| 83 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.01878594 |
| 84 | TP63_23658742_ChIP-Seq_EP156T_Human | 1.00670183 |
| 85 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 1.00036743 |
| 86 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.99220840 |
| 87 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.99042757 |
| 88 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.99022164 |
| 89 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.98278385 |
| 90 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 0.97942836 |
| 91 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.97604431 |
| 92 | * KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.97350508 |
| 93 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 0.97241413 |
| 94 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.96861658 |
| 95 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.96783052 |
| 96 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.96773204 |
| 97 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.96128185 |
| 98 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.95273056 |
| 99 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.95189527 |
| 100 | CBP_21632823_ChIP-Seq_H3396_Human | 0.94634018 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002139_abnormal_hepatobiliary_system | 5.26629362 |
| 2 | MP0002837_dystrophic_cardiac_calcinosis | 4.81156461 |
| 3 | MP0004084_abnormal_cardiac_muscle | 4.43371369 |
| 4 | MP0000751_myopathy | 4.03748652 |
| 5 | MP0003011_delayed_dark_adaptation | 3.79506976 |
| 6 | MP0004215_abnormal_myocardial_fiber | 3.48630537 |
| 7 | MP0002138_abnormal_hepatobiliary_system | 3.32465370 |
| 8 | MP0004484_altered_response_of | 3.01238787 |
| 9 | MP0004036_abnormal_muscle_relaxation | 2.93410640 |
| 10 | MP0003195_calcinosis | 2.85532643 |
| 11 | MP0005330_cardiomyopathy | 2.81896277 |
| 12 | MP0006138_congestive_heart_failure | 2.65850443 |
| 13 | MP0002972_abnormal_cardiac_muscle | 2.64645064 |
| 14 | MP0003646_muscle_fatigue | 2.60137493 |
| 15 | MP0003880_abnormal_central_pattern | 2.42985534 |
| 16 | MP0005084_abnormal_gallbladder_morpholo | 2.35007144 |
| 17 | MP0008775_abnormal_heart_ventricle | 2.31481649 |
| 18 | MP0003183_abnormal_peptide_metabolism | 2.30585041 |
| 19 | MP0003950_abnormal_plasma_membrane | 2.30191767 |
| 20 | MP0000749_muscle_degeneration | 2.28196037 |
| 21 | MP0004272_abnormal_basement_membrane | 2.27393223 |
| 22 | MP0005670_abnormal_white_adipose | 2.23571481 |
| 23 | MP0002269_muscular_atrophy | 2.14860622 |
| 24 | MP0005385_cardiovascular_system_phenoty | 2.13554955 |
| 25 | MP0001544_abnormal_cardiovascular_syste | 2.13554955 |
| 26 | MP0003137_abnormal_impulse_conducting | 2.03797288 |
| 27 | MP0001666_abnormal_nutrient_absorption | 1.99453505 |
| 28 | MP0003252_abnormal_bile_duct | 1.94674487 |
| 29 | MP0004087_abnormal_muscle_fiber | 1.94584861 |
| 30 | MP0004085_abnormal_heartbeat | 1.93050492 |
| 31 | MP0001986_abnormal_taste_sensitivity | 1.90837468 |
| 32 | MP0005620_abnormal_muscle_contractility | 1.84294223 |
| 33 | MP0005165_increased_susceptibility_to | 1.70649387 |
| 34 | MP0002127_abnormal_cardiovascular_syste | 1.69847565 |
| 35 | MP0010630_abnormal_cardiac_muscle | 1.69155002 |
| 36 | MP0005365_abnormal_bile_salt | 1.61728063 |
| 37 | MP0005551_abnormal_eye_electrophysiolog | 1.60288351 |
| 38 | MP0005423_abnormal_somatic_nervous | 1.59505201 |
| 39 | MP0003828_pulmonary_edema | 1.53483775 |
| 40 | MP0000747_muscle_weakness | 1.53322126 |
| 41 | MP0003868_abnormal_feces_composition | 1.52807212 |
| 42 | MP0004510_myositis | 1.44808213 |
| 43 | MP0000003_abnormal_adipose_tissue | 1.35284807 |
| 44 | MP0004130_abnormal_muscle_cell | 1.33637057 |
| 45 | MP0009780_abnormal_chondrocyte_physiolo | 1.32958193 |
| 46 | MP0000750_abnormal_muscle_regeneration | 1.31130151 |
| 47 | MP0002234_abnormal_pharynx_morphology | 1.29409331 |
| 48 | MP0010386_abnormal_urinary_bladder | 1.27379778 |
| 49 | MP0002928_abnormal_bile_duct | 1.25723184 |
| 50 | MP0005253_abnormal_eye_physiology | 1.24962322 |
| 51 | MP0005085_abnormal_gallbladder_physiolo | 1.22120905 |
| 52 | MP0002332_abnormal_exercise_endurance | 1.21901384 |
| 53 | MP0002638_abnormal_pupillary_reflex | 1.19694460 |
| 54 | MP0004233_abnormal_muscle_weight | 1.17447762 |
| 55 | MP0002106_abnormal_muscle_physiology | 1.13080059 |
| 56 | MP0010678_abnormal_skin_adnexa | 1.11126729 |
| 57 | MP0006276_abnormal_autonomic_nervous | 1.09425964 |
| 58 | MP0003191_abnormal_cellular_cholesterol | 1.04568297 |
| 59 | MP0003879_abnormal_hair_cell | 1.02123505 |
| 60 | MP0002089_abnormal_postnatal_growth/wei | 1.01375101 |
| 61 | MP0005187_abnormal_penis_morphology | 0.99088423 |
| 62 | MP0005369_muscle_phenotype | 0.94738800 |
| 63 | MP0001502_abnormal_circadian_rhythm | 0.94073660 |
| 64 | MP0000759_abnormal_skeletal_muscle | 0.93756387 |
| 65 | MP0002295_abnormal_pulmonary_circulatio | 0.93616115 |
| 66 | MP0008569_lethality_at_weaning | 0.90105983 |
| 67 | MP0002102_abnormal_ear_morphology | 0.89023667 |
| 68 | MP0010368_abnormal_lymphatic_system | 0.86882611 |
| 69 | MP0005595_abnormal_vascular_smooth | 0.76593176 |
| 70 | MP0003941_abnormal_skin_development | 0.76151658 |
| 71 | MP0005375_adipose_tissue_phenotype | 0.74037040 |
| 72 | MP0001661_extended_life_span | 0.73312767 |
| 73 | MP0000343_altered_response_to | 0.73210777 |
| 74 | MP0005266_abnormal_metabolism | 0.71525917 |
| 75 | MP0005257_abnormal_intraocular_pressure | 0.70908759 |
| 76 | MP0005220_abnormal_exocrine_pancreas | 0.68592731 |
| 77 | MP0001984_abnormal_olfaction | 0.68150973 |
| 78 | MP0000266_abnormal_heart_morphology | 0.67303063 |
| 79 | MP0000230_abnormal_systemic_arterial | 0.64515762 |
| 80 | MP0003283_abnormal_digestive_organ | 0.62550660 |
| 81 | MP0003633_abnormal_nervous_system | 0.61831807 |
| 82 | MP0002118_abnormal_lipid_homeostasis | 0.60861980 |
| 83 | MP0001851_eye_inflammation | 0.59989691 |
| 84 | MP0001664_abnormal_digestion | 0.59108185 |
| 85 | MP0001501_abnormal_sleep_pattern | 0.58630283 |
| 86 | MP0004145_abnormal_muscle_electrophysio | 0.57737055 |
| 87 | MP0001270_distended_abdomen | 0.57192983 |
| 88 | MP0003136_yellow_coat_color | 0.57076853 |
| 89 | MP0002108_abnormal_muscle_morphology | 0.54153795 |
| 90 | MP0003959_abnormal_lean_body | 0.52943201 |
| 91 | MP0005332_abnormal_amino_acid | 0.52220481 |
| 92 | MP0006036_abnormal_mitochondrial_physio | 0.51570168 |
| 93 | MP0002128_abnormal_blood_circulation | 0.51335752 |
| 94 | MP0002229_neurodegeneration | 0.50489307 |
| 95 | MP0005195_abnormal_posterior_eye | 0.50076698 |
| 96 | MP0005197_abnormal_uvea_morphology | 0.49334715 |
| 97 | MP0004134_abnormal_chest_morphology | 0.48312928 |
| 98 | MP0006082_CNS_inflammation | 0.48094380 |
| 99 | MP0002896_abnormal_bone_mineralization | 0.47937118 |
| 100 | MP0002090_abnormal_vision | 0.46724804 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Sudden death (HP:0001699) | 6.92077896 |
| 2 | Bundle branch block (HP:0011710) | 6.77057452 |
| 3 | Hyporeflexia of lower limbs (HP:0002600) | 6.12903554 |
| 4 | Atrial fibrillation (HP:0005110) | 5.90817410 |
| 5 | Lipoatrophy (HP:0100578) | 5.58398328 |
| 6 | Ventricular tachycardia (HP:0004756) | 5.49268088 |
| 7 | Asymmetric septal hypertrophy (HP:0001670) | 5.41114249 |
| 8 | Primary atrial arrhythmia (HP:0001692) | 5.37755953 |
| 9 | Supraventricular tachycardia (HP:0004755) | 5.17609883 |
| 10 | Muscle fiber splitting (HP:0003555) | 5.14552077 |
| 11 | Supraventricular arrhythmia (HP:0005115) | 5.02464305 |
| 12 | Abnormality of the calf musculature (HP:0001430) | 4.83859538 |
| 13 | Dilated cardiomyopathy (HP:0001644) | 4.50588474 |
| 14 | Syncope (HP:0001279) | 4.47470828 |
| 15 | Distal lower limb muscle weakness (HP:0009053) | 4.29535807 |
| 16 | Right ventricular cardiomyopathy (HP:0011663) | 4.22848743 |
| 17 | Heart block (HP:0012722) | 4.16496402 |
| 18 | Late onset (HP:0003584) | 4.08962438 |
| 19 | Abnormal pancreas size (HP:0012094) | 4.05130191 |
| 20 | Calf muscle hypertrophy (HP:0008981) | 4.04219103 |
| 21 | Subaortic stenosis (HP:0001682) | 3.94161786 |
| 22 | Abnormality of the left ventricular outflow tract (HP:0011103) | 3.94161786 |
| 23 | EMG: myopathic abnormalities (HP:0003458) | 3.93779514 |
| 24 | Abnormal atrioventricular conduction (HP:0005150) | 3.84855535 |
| 25 | Ventricular arrhythmia (HP:0004308) | 3.75292630 |
| 26 | EMG: neuropathic changes (HP:0003445) | 3.67225904 |
| 27 | Gout (HP:0001997) | 3.56151397 |
| 28 | Muscle hypertrophy of the lower extremities (HP:0008968) | 3.50350563 |
| 29 | Congenital stationary night blindness (HP:0007642) | 3.48782747 |
| 30 | Left ventricular hypertrophy (HP:0001712) | 3.39682148 |
| 31 | Unilateral renal agenesis (HP:0000122) | 3.34177572 |
| 32 | Abnormality of proline metabolism (HP:0010907) | 3.32217000 |
| 33 | Hydroxyprolinuria (HP:0003080) | 3.32217000 |
| 34 | Prolonged QT interval (HP:0001657) | 3.17764460 |
| 35 | Glucose intolerance (HP:0000833) | 3.17145627 |
| 36 | Exocrine pancreatic insufficiency (HP:0001738) | 3.12548431 |
| 37 | Palpitations (HP:0001962) | 3.09757396 |
| 38 | Atrioventricular block (HP:0001678) | 3.04533680 |
| 39 | Central scotoma (HP:0000603) | 3.04095788 |
| 40 | Action tremor (HP:0002345) | 2.94270651 |
| 41 | Abnormality of the foot musculature (HP:0001436) | 2.93126662 |
| 42 | Resting tremor (HP:0002322) | 2.87823809 |
| 43 | Ragged-red muscle fibers (HP:0003200) | 2.84485473 |
| 44 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.84080179 |
| 45 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.84080179 |
| 46 | Abnormality of glycolipid metabolism (HP:0010969) | 2.84080179 |
| 47 | Scotoma (HP:0000575) | 2.81969441 |
| 48 | Steatorrhea (HP:0002570) | 2.76216827 |
| 49 | Areflexia of lower limbs (HP:0002522) | 2.75217240 |
| 50 | Abnormal EKG (HP:0003115) | 2.66302832 |
| 51 | Neck muscle weakness (HP:0000467) | 2.65487791 |
| 52 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.63048363 |
| 53 | Gonadotropin excess (HP:0000837) | 2.59132250 |
| 54 | Type 1 muscle fiber predominance (HP:0003803) | 2.57259686 |
| 55 | Palmoplantar keratoderma (HP:0000982) | 2.55765793 |
| 56 | Polar cataract (HP:0010696) | 2.44150491 |
| 57 | Ventricular fibrillation (HP:0001663) | 2.39983206 |
| 58 | Tubulointerstitial nephritis (HP:0001970) | 2.39834948 |
| 59 | Posterior subcapsular cataract (HP:0007787) | 2.39015816 |
| 60 | Myoglobinuria (HP:0002913) | 2.37379433 |
| 61 | Hypoplasia of the uterus (HP:0000013) | 2.36544852 |
| 62 | Sensorimotor neuropathy (HP:0007141) | 2.36450420 |
| 63 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.32045010 |
| 64 | Foot dorsiflexor weakness (HP:0009027) | 2.31781880 |
| 65 | Congenital sensorineural hearing impairment (HP:0008527) | 2.29636850 |
| 66 | Abnormal glucose tolerance (HP:0001952) | 2.24224840 |
| 67 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.22530377 |
| 68 | Attenuation of retinal blood vessels (HP:0007843) | 2.20015672 |
| 69 | Sudden cardiac death (HP:0001645) | 2.15754661 |
| 70 | Shawl scrotum (HP:0000049) | 2.12051925 |
| 71 | Subcapsular cataract (HP:0000523) | 2.09279777 |
| 72 | Increased purine levels (HP:0004368) | 2.06065279 |
| 73 | Hyperuricemia (HP:0002149) | 2.06065279 |
| 74 | Postural tremor (HP:0002174) | 2.05852565 |
| 75 | Increased serum pyruvate (HP:0003542) | 1.99375361 |
| 76 | Glycosuria (HP:0003076) | 1.98379272 |
| 77 | Abnormality of urine glucose concentration (HP:0011016) | 1.98379272 |
| 78 | Fat malabsorption (HP:0002630) | 1.95006165 |
| 79 | Tetraparesis (HP:0002273) | 1.93445597 |
| 80 | Tubular atrophy (HP:0000092) | 1.93240196 |
| 81 | Congestive heart failure (HP:0001635) | 1.90416868 |
| 82 | Ulnar claw (HP:0001178) | 1.88928893 |
| 83 | Cone-rod dystrophy (HP:0000548) | 1.83478200 |
| 84 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 1.82230896 |
| 85 | Difficulty running (HP:0009046) | 1.82110561 |
| 86 | Double outlet right ventricle (HP:0001719) | 1.81349383 |
| 87 | Congenital malformation of the right heart (HP:0011723) | 1.81349383 |
| 88 | Papillary thyroid carcinoma (HP:0002895) | 1.78884336 |
| 89 | Muscular dystrophy (HP:0003560) | 1.77869797 |
| 90 | Abolished electroretinogram (ERG) (HP:0000550) | 1.76794522 |
| 91 | Abnormality of glycolysis (HP:0004366) | 1.76220575 |
| 92 | Increased connective tissue (HP:0009025) | 1.73192858 |
| 93 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.73000047 |
| 94 | Autoamputation (HP:0001218) | 1.71905691 |
| 95 | Neoplasm of head and neck (HP:0012288) | 1.70816265 |
| 96 | Esophageal neoplasm (HP:0100751) | 1.70816265 |
| 97 | Steppage gait (HP:0003376) | 1.70190000 |
| 98 | Hypoproteinemia (HP:0003075) | 1.68817102 |
| 99 | Generalized muscle weakness (HP:0003324) | 1.68342966 |
| 100 | Rhabdomyolysis (HP:0003201) | 1.67523493 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MYLK | 8.68354175 |
| 2 | TTN | 5.88527579 |
| 3 | PINK1 | 2.89073474 |
| 4 | PAK3 | 2.77998654 |
| 5 | GRK1 | 2.50408146 |
| 6 | MST4 | 2.41230235 |
| 7 | FRK | 2.24639006 |
| 8 | DMPK | 2.14500952 |
| 9 | TRPM7 | 1.94675467 |
| 10 | PIK3CA | 1.91173490 |
| 11 | MAP3K12 | 1.88794360 |
| 12 | NTRK3 | 1.87616867 |
| 13 | MAP4K2 | 1.81196827 |
| 14 | CDK19 | 1.71383775 |
| 15 | BCKDK | 1.65355425 |
| 16 | PRKCE | 1.63396940 |
| 17 | INSRR | 1.61772355 |
| 18 | STK4 | 1.57787767 |
| 19 | PDK2 | 1.57334527 |
| 20 | PKN2 | 1.55509100 |
| 21 | NEK9 | 1.51316659 |
| 22 | OBSCN | 1.43807150 |
| 23 | ROCK2 | 1.32926978 |
| 24 | MARK1 | 1.29707708 |
| 25 | MUSK | 1.28672631 |
| 26 | MAP3K7 | 1.28191806 |
| 27 | PRKD1 | 1.22468025 |
| 28 | MAP3K3 | 1.19332825 |
| 29 | MST1R | 1.16936919 |
| 30 | ROCK1 | 1.16314307 |
| 31 | FLT3 | 1.09518919 |
| 32 | PKN1 | 1.03353095 |
| 33 | PLK2 | 1.01726249 |
| 34 | MAPKAPK3 | 0.95888250 |
| 35 | EPHA3 | 0.95148874 |
| 36 | CAMK2A | 0.94039135 |
| 37 | TIE1 | 0.89029095 |
| 38 | BCR | 0.86839374 |
| 39 | RPS6KL1 | 0.85537664 |
| 40 | RPS6KC1 | 0.85537664 |
| 41 | PRKAA1 | 0.85435726 |
| 42 | RPS6KA6 | 0.83875608 |
| 43 | DAPK2 | 0.81652523 |
| 44 | TGFBR2 | 0.79075123 |
| 45 | EPHA2 | 0.79025468 |
| 46 | MAP3K6 | 0.76980917 |
| 47 | BRSK2 | 0.76269498 |
| 48 | NEK1 | 0.75695318 |
| 49 | DAPK3 | 0.74986995 |
| 50 | MAP2K1 | 0.72840482 |
| 51 | STK38L | 0.70484445 |
| 52 | MAPK13 | 0.70418878 |
| 53 | MAP3K5 | 0.70044434 |
| 54 | MAPK12 | 0.69076739 |
| 55 | LMTK2 | 0.67991525 |
| 56 | ERN1 | 0.66927062 |
| 57 | CAMK2D | 0.63522866 |
| 58 | CASK | 0.63340273 |
| 59 | STK24 | 0.61795260 |
| 60 | PRKAA2 | 0.58560584 |
| 61 | ADRBK1 | 0.54789000 |
| 62 | EIF2AK3 | 0.54212835 |
| 63 | PRKG1 | 0.53927918 |
| 64 | CAMK1 | 0.48409944 |
| 65 | STK38 | 0.47975132 |
| 66 | AKT2 | 0.47313151 |
| 67 | MAPK7 | 0.46646933 |
| 68 | CAMK2G | 0.46162065 |
| 69 | FER | 0.45074064 |
| 70 | PRKACA | 0.44767909 |
| 71 | PRKACG | 0.42100696 |
| 72 | CAMK4 | 0.41875706 |
| 73 | AKT3 | 0.41034047 |
| 74 | MET | 0.39575731 |
| 75 | SGK2 | 0.38431284 |
| 76 | PRKCQ | 0.37028693 |
| 77 | RIPK1 | 0.36615954 |
| 78 | LATS1 | 0.36092960 |
| 79 | IRAK1 | 0.35662900 |
| 80 | ILK | 0.33977032 |
| 81 | PRKCA | 0.32513699 |
| 82 | EPHB2 | 0.31959474 |
| 83 | BRAF | 0.31465511 |
| 84 | PRKACB | 0.30711874 |
| 85 | ARAF | 0.30361882 |
| 86 | PHKG1 | 0.30287682 |
| 87 | PHKG2 | 0.30287682 |
| 88 | GRK7 | 0.29939385 |
| 89 | PRKCD | 0.29591211 |
| 90 | ADRBK2 | 0.29109682 |
| 91 | ERBB4 | 0.28724981 |
| 92 | CDC42BPA | 0.26549312 |
| 93 | PDK1 | 0.25362089 |
| 94 | PRKD2 | 0.24114913 |
| 95 | CAMK2B | 0.23934032 |
| 96 | PTK2B | 0.23665214 |
| 97 | RPS6KA1 | 0.22692230 |
| 98 | MAPK10 | 0.22442463 |
| 99 | EPHA4 | 0.21349369 |
| 100 | SGK223 | 0.20532463 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Pancreatic secretion_Homo sapiens_hsa04972 | 4.35894252 |
| 2 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 3.99558706 |
| 3 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 3.44793781 |
| 4 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 3.35348856 |
| 5 | Fat digestion and absorption_Homo sapiens_hsa04975 | 3.23919332 |
| 6 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.95953280 |
| 7 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.92601181 |
| 8 | * Phototransduction_Homo sapiens_hsa04744 | 2.61192014 |
| 9 | Protein digestion and absorption_Homo sapiens_hsa04974 | 2.52574011 |
| 10 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.26239663 |
| 11 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 2.18428078 |
| 12 | Circadian rhythm_Homo sapiens_hsa04710 | 2.12768133 |
| 13 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.92059986 |
| 14 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.77389100 |
| 15 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.75316730 |
| 16 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.73653449 |
| 17 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.69688732 |
| 18 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.54893322 |
| 19 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.52956948 |
| 20 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.50593086 |
| 21 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.39401947 |
| 22 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.36566397 |
| 23 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.30627915 |
| 24 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.21859349 |
| 25 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.20340783 |
| 26 | Nicotine addiction_Homo sapiens_hsa05033 | 1.16888072 |
| 27 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.07469259 |
| 28 | Taste transduction_Homo sapiens_hsa04742 | 1.06426896 |
| 29 | Morphine addiction_Homo sapiens_hsa05032 | 1.00305075 |
| 30 | Olfactory transduction_Homo sapiens_hsa04740 | 0.96223685 |
| 31 | GABAergic synapse_Homo sapiens_hsa04727 | 0.96119557 |
| 32 | Galactose metabolism_Homo sapiens_hsa00052 | 0.94587437 |
| 33 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.92993640 |
| 34 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.91577328 |
| 35 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.91078868 |
| 36 | Bile secretion_Homo sapiens_hsa04976 | 0.90338964 |
| 37 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.90146369 |
| 38 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.88896341 |
| 39 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.88181917 |
| 40 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.87269452 |
| 41 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.84166235 |
| 42 | Insulin secretion_Homo sapiens_hsa04911 | 0.82961915 |
| 43 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.81190134 |
| 44 | Salivary secretion_Homo sapiens_hsa04970 | 0.77451308 |
| 45 | Carbon metabolism_Homo sapiens_hsa01200 | 0.77397081 |
| 46 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.76683924 |
| 47 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.75875044 |
| 48 | Parkinsons disease_Homo sapiens_hsa05012 | 0.74361174 |
| 49 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.72206353 |
| 50 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.72187211 |
| 51 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.71681853 |
| 52 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.70317282 |
| 53 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.70167033 |
| 54 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.69819536 |
| 55 | ABC transporters_Homo sapiens_hsa02010 | 0.68060149 |
| 56 | Renin secretion_Homo sapiens_hsa04924 | 0.66889665 |
| 57 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.66439005 |
| 58 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.65961398 |
| 59 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.65236585 |
| 60 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.64517571 |
| 61 | Circadian entrainment_Homo sapiens_hsa04713 | 0.64485737 |
| 62 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.63990986 |
| 63 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.63249182 |
| 64 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.62693981 |
| 65 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.62276164 |
| 66 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.61580557 |
| 67 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.60941489 |
| 68 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.60305230 |
| 69 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.58394163 |
| 70 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.55620633 |
| 71 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.50595175 |
| 72 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.49531229 |
| 73 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.48050491 |
| 74 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.47856354 |
| 75 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.46469242 |
| 76 | Alzheimers disease_Homo sapiens_hsa05010 | 0.46395780 |
| 77 | Focal adhesion_Homo sapiens_hsa04510 | 0.45024785 |
| 78 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.44108039 |
| 79 | Insulin resistance_Homo sapiens_hsa04931 | 0.43708760 |
| 80 | Adherens junction_Homo sapiens_hsa04520 | 0.42885933 |
| 81 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.42857817 |
| 82 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.42725126 |
| 83 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.41982385 |
| 84 | Other glycan degradation_Homo sapiens_hsa00511 | 0.41875524 |
| 85 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.41663396 |
| 86 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.41417219 |
| 87 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.40579736 |
| 88 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.40055710 |
| 89 | Cocaine addiction_Homo sapiens_hsa05030 | 0.39376696 |
| 90 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.38098317 |
| 91 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.37156726 |
| 92 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.33595291 |
| 93 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.32951232 |
| 94 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.31968162 |
| 95 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.30690663 |
| 96 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.30434325 |
| 97 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.30405395 |
| 98 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.29438609 |
| 99 | Huntingtons disease_Homo sapiens_hsa05016 | 0.28898704 |
| 100 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.28494020 |

