

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | sperm capacitation (GO:0048240) | 6.61951716 |
| 2 | multicellular organism reproduction (GO:0032504) | 6.61920006 |
| 3 | sperm motility (GO:0030317) | 6.58565559 |
| 4 | pyrimidine-containing compound transmembrane transport (GO:0072531) | 6.21616139 |
| 5 | cellular ketone body metabolic process (GO:0046950) | 5.94773857 |
| 6 | fucose catabolic process (GO:0019317) | 5.67876382 |
| 7 | L-fucose metabolic process (GO:0042354) | 5.67876382 |
| 8 | L-fucose catabolic process (GO:0042355) | 5.67876382 |
| 9 | vitamin transmembrane transport (GO:0035461) | 5.57692919 |
| 10 | positive regulation of triglyceride biosynthetic process (GO:0010867) | 5.34605282 |
| 11 | ketone body metabolic process (GO:1902224) | 5.23581732 |
| 12 | inner ear receptor cell differentiation (GO:0060113) | 4.82237158 |
| 13 | negative regulation of mesenchymal cell apoptotic process (GO:2001054) | 4.80520521 |
| 14 | centriole replication (GO:0007099) | 4.67574363 |
| 15 | reproduction (GO:0000003) | 4.57319373 |
| 16 | regulation of memory T cell differentiation (GO:0043380) | 4.44870491 |
| 17 | regulation of triglyceride biosynthetic process (GO:0010866) | 4.42764637 |
| 18 | glomerular visceral epithelial cell development (GO:0072015) | 4.42672739 |
| 19 | nephron tubule morphogenesis (GO:0072078) | 4.42295297 |
| 20 | nephron epithelium morphogenesis (GO:0072088) | 4.42295297 |
| 21 | cellular response to exogenous dsRNA (GO:0071360) | 4.38273498 |
| 22 | macroautophagy (GO:0016236) | 4.28864196 |
| 23 | cilium or flagellum-dependent cell motility (GO:0001539) | 4.21099858 |
| 24 | establishment of protein localization to Golgi (GO:0072600) | 4.15367545 |
| 25 | regulation of mesenchymal cell apoptotic process (GO:2001053) | 4.12729702 |
| 26 | glomerular epithelial cell development (GO:0072310) | 4.12668436 |
| 27 | protein targeting to Golgi (GO:0000042) | 4.11515862 |
| 28 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 4.06439164 |
| 29 | regulation of translation, ncRNA-mediated (GO:0045974) | 4.06439164 |
| 30 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 4.06439164 |
| 31 | fusion of sperm to egg plasma membrane (GO:0007342) | 3.99045177 |
| 32 | RNA destabilization (GO:0050779) | 3.90510200 |
| 33 | positive regulation of defense response to virus by host (GO:0002230) | 3.86381447 |
| 34 | behavioral response to nicotine (GO:0035095) | 3.84483500 |
| 35 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 3.82853051 |
| 36 | negative regulation of inclusion body assembly (GO:0090084) | 3.81658065 |
| 37 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 3.73132048 |
| 38 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.68566833 |
| 39 | protein polyglutamylation (GO:0018095) | 3.67121916 |
| 40 | sperm-egg recognition (GO:0035036) | 3.58960173 |
| 41 | mechanoreceptor differentiation (GO:0042490) | 3.52507917 |
| 42 | regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358) | 3.51486635 |
| 43 | protein localization to Golgi apparatus (GO:0034067) | 3.49147771 |
| 44 | positive regulation of triglyceride metabolic process (GO:0090208) | 3.47078521 |
| 45 | centriole assembly (GO:0098534) | 3.42785600 |
| 46 | protein localization to cytoskeleton (GO:0044380) | 3.38836116 |
| 47 | regulation of centriole replication (GO:0046599) | 3.34879854 |
| 48 | protein localization to microtubule cytoskeleton (GO:0072698) | 3.34757611 |
| 49 | membrane depolarization during action potential (GO:0086010) | 3.33528752 |
| 50 | tolerance induction (GO:0002507) | 3.32489931 |
| 51 | protein K48-linked deubiquitination (GO:0071108) | 3.31976959 |
| 52 | single fertilization (GO:0007338) | 3.31842362 |
| 53 | microtubule polymerization or depolymerization (GO:0031109) | 3.28741668 |
| 54 | negative regulation of reactive oxygen species metabolic process (GO:2000378) | 3.27143729 |
| 55 | plasma membrane fusion (GO:0045026) | 3.27122207 |
| 56 | microtubule depolymerization (GO:0007019) | 3.25677649 |
| 57 | regulation of triglyceride catabolic process (GO:0010896) | 3.24646067 |
| 58 | positive regulation of CREB transcription factor activity (GO:0032793) | 3.21580170 |
| 59 | piRNA metabolic process (GO:0034587) | 3.19470445 |
| 60 | positive regulation of endothelial cell differentiation (GO:0045603) | 3.15318817 |
| 61 | primary amino compound metabolic process (GO:1901160) | 3.14304182 |
| 62 | cornea development in camera-type eye (GO:0061303) | 3.13017660 |
| 63 | fertilization (GO:0009566) | 3.12530491 |
| 64 | auditory receptor cell stereocilium organization (GO:0060088) | 3.12491581 |
| 65 | tryptophan catabolic process (GO:0006569) | 3.12356797 |
| 66 | indole-containing compound catabolic process (GO:0042436) | 3.12356797 |
| 67 | indolalkylamine catabolic process (GO:0046218) | 3.12356797 |
| 68 | cell-cell recognition (GO:0009988) | 3.08201548 |
| 69 | natural killer cell activation involved in immune response (GO:0002323) | 3.08034660 |
| 70 | regulation of triglyceride metabolic process (GO:0090207) | 3.06686563 |
| 71 | calcium ion import (GO:0070509) | 3.01973942 |
| 72 | cysteine metabolic process (GO:0006534) | 3.01863426 |
| 73 | axoneme assembly (GO:0035082) | 3.00869498 |
| 74 | regulation of sequestering of triglyceride (GO:0010889) | 2.99519105 |
| 75 | sulfur compound transport (GO:0072348) | 2.95917802 |
| 76 | response to misfolded protein (GO:0051788) | 2.94738469 |
| 77 | fucosylation (GO:0036065) | 2.94290007 |
| 78 | axonemal dynein complex assembly (GO:0070286) | 2.90184815 |
| 79 | positive regulation of fatty acid oxidation (GO:0046321) | 2.89609830 |
| 80 | male meiosis (GO:0007140) | 2.88739150 |
| 81 | seminiferous tubule development (GO:0072520) | 2.88166568 |
| 82 | spermatid development (GO:0007286) | 2.87722039 |
| 83 | acrosome reaction (GO:0007340) | 2.86501438 |
| 84 | fucose metabolic process (GO:0006004) | 2.83270255 |
| 85 | rRNA catabolic process (GO:0016075) | 2.83221907 |
| 86 | regulation of rhodopsin mediated signaling pathway (GO:0022400) | 2.83100004 |
| 87 | rhodopsin mediated signaling pathway (GO:0016056) | 2.82752436 |
| 88 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.81802597 |
| 89 | male gamete generation (GO:0048232) | 2.81627053 |
| 90 | spermatogenesis (GO:0007283) | 2.81167956 |
| 91 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.75817579 |
| 92 | detection of light stimulus involved in visual perception (GO:0050908) | 2.75817579 |
| 93 | lytic vacuole organization (GO:0080171) | 2.74985137 |
| 94 | lysosome organization (GO:0007040) | 2.74985137 |
| 95 | opioid receptor signaling pathway (GO:0038003) | 2.74449023 |
| 96 | organic cation transport (GO:0015695) | 2.74160786 |
| 97 | male meiosis I (GO:0007141) | 2.71737457 |
| 98 | motile cilium assembly (GO:0044458) | 2.71545799 |
| 99 | negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642) | 2.70587342 |
| 100 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.70389138 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.68485199 |
| 2 | ZNF274_21170338_ChIP-Seq_K562_Hela | 4.43383030 |
| 3 | GATA1_22025678_ChIP-Seq_K562_Human | 3.23826942 |
| 4 | VDR_22108803_ChIP-Seq_LS180_Human | 3.20155420 |
| 5 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.09056105 |
| 6 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.06477199 |
| 7 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 2.27907127 |
| 8 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.27907127 |
| 9 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.22310762 |
| 10 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 2.17392080 |
| 11 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.09880806 |
| 12 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 2.02719785 |
| 13 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.00264032 |
| 14 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.87732467 |
| 15 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.84081539 |
| 16 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.73859195 |
| 17 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.69628758 |
| 18 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.60342981 |
| 19 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.53050304 |
| 20 | FUS_26573619_Chip-Seq_HEK293_Human | 1.51172832 |
| 21 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.50474201 |
| 22 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.50042992 |
| 23 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.48768721 |
| 24 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.48544058 |
| 25 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 1.48501913 |
| 26 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.48484457 |
| 27 | STAT3_23295773_ChIP-Seq_U87_Human | 1.45822121 |
| 28 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.44337450 |
| 29 | * FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.43652913 |
| 30 | * FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.43652913 |
| 31 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.43484415 |
| 32 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.41412613 |
| 33 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.39123487 |
| 34 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.38809800 |
| 35 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.38809800 |
| 36 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.38488148 |
| 37 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.37788762 |
| 38 | P300_19829295_ChIP-Seq_ESCs_Human | 1.37398532 |
| 39 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.37234637 |
| 40 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.35459702 |
| 41 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.34980466 |
| 42 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.33190682 |
| 43 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.32143373 |
| 44 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.32143373 |
| 45 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.30743897 |
| 46 | AR_25329375_ChIP-Seq_VCAP_Human | 1.30450170 |
| 47 | * ERA_21632823_ChIP-Seq_H3396_Human | 1.30209931 |
| 48 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.26868291 |
| 49 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.25725258 |
| 50 | TCF4_23295773_ChIP-Seq_U87_Human | 1.22381494 |
| 51 | * NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.21838372 |
| 52 | * FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.21336197 |
| 53 | TP53_16413492_ChIP-PET_HCT116_Human | 1.21322357 |
| 54 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.21164573 |
| 55 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.19898217 |
| 56 | * HOXB7_26014856_ChIP-Seq_BT474_Human | 1.19133261 |
| 57 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.18794699 |
| 58 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.18211046 |
| 59 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.17746727 |
| 60 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.17122338 |
| 61 | RAC3_21632823_ChIP-Seq_H3396_Human | 1.15095540 |
| 62 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.15034021 |
| 63 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.12570893 |
| 64 | AR_20517297_ChIP-Seq_VCAP_Human | 1.12284143 |
| 65 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.12066055 |
| 66 | OCT4_20526341_ChIP-Seq_ESCs_Human | 1.12041024 |
| 67 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.07902497 |
| 68 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.07470488 |
| 69 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.06915870 |
| 70 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.06528714 |
| 71 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.06396982 |
| 72 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.06284156 |
| 73 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.05380412 |
| 74 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.04191293 |
| 75 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.03607998 |
| 76 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.03404289 |
| 77 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.03261040 |
| 78 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.03140832 |
| 79 | * GATA4_25053715_ChIP-Seq_YYC3_Human | 1.02790919 |
| 80 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.01946043 |
| 81 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.01927608 |
| 82 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.01847857 |
| 83 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.01205349 |
| 84 | NFYB_21822215_ChIP-Seq_K562_Human | 1.00462155 |
| 85 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.00247715 |
| 86 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.00220709 |
| 87 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.99827754 |
| 88 | * TCF4_22108803_ChIP-Seq_LS180_Human | 0.99079024 |
| 89 | * CEBPB_22108803_ChIP-Seq_LS180_Human | 0.98838381 |
| 90 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.97965860 |
| 91 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.97671140 |
| 92 | OCT1_27270436_Chip-Seq_PROSTATE_Human | 0.97182901 |
| 93 | CBX2_22325352_ChIP-Seq_293T-Rex_Human | 0.96835121 |
| 94 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.96442881 |
| 95 | TBL1_22424771_ChIP-Seq_293T_Human | 0.95572428 |
| 96 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.95234501 |
| 97 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.95148097 |
| 98 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.94564958 |
| 99 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.94246545 |
| 100 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.93200294 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005377_hearing/vestibular/ear_phenot | 5.27427726 |
| 2 | MP0003878_abnormal_ear_physiology | 5.27427726 |
| 3 | MP0003195_calcinosis | 4.77582964 |
| 4 | MP0001485_abnormal_pinna_reflex | 4.43630720 |
| 5 | MP0005410_abnormal_fertilization | 3.72936244 |
| 6 | MP0004742_abnormal_vestibular_system | 3.67280855 |
| 7 | MP0003136_yellow_coat_color | 3.54154640 |
| 8 | MP0002102_abnormal_ear_morphology | 2.97634786 |
| 9 | MP0004885_abnormal_endolymph | 2.83236868 |
| 10 | MP0003879_abnormal_hair_cell | 2.61247824 |
| 11 | MP0005670_abnormal_white_adipose | 2.54117114 |
| 12 | MP0008877_abnormal_DNA_methylation | 2.47555292 |
| 13 | MP0009780_abnormal_chondrocyte_physiolo | 2.25825310 |
| 14 | MP0002876_abnormal_thyroid_physiology | 2.15334395 |
| 15 | MP0008875_abnormal_xenobiotic_pharmacok | 2.11993579 |
| 16 | MP0004147_increased_porphyrin_level | 2.08756655 |
| 17 | MP0009840_abnormal_foam_cell | 2.07155484 |
| 18 | MP0002653_abnormal_ependyma_morphology | 1.97067414 |
| 19 | MP0001986_abnormal_taste_sensitivity | 1.97045614 |
| 20 | MP0001929_abnormal_gametogenesis | 1.74318141 |
| 21 | MP0008872_abnormal_physiological_respon | 1.73018843 |
| 22 | MP0003698_abnormal_male_reproductive | 1.72968745 |
| 23 | MP0010329_abnormal_lipoprotein_level | 1.62574937 |
| 24 | MP0003718_maternal_effect | 1.52158116 |
| 25 | MP0009745_abnormal_behavioral_response | 1.50975905 |
| 26 | MP0001968_abnormal_touch/_nociception | 1.50043924 |
| 27 | MP0004142_abnormal_muscle_tone | 1.47336798 |
| 28 | MP0001486_abnormal_startle_reflex | 1.46686586 |
| 29 | MP0000230_abnormal_systemic_arterial | 1.45616008 |
| 30 | MP0005551_abnormal_eye_electrophysiolog | 1.44975068 |
| 31 | MP0005365_abnormal_bile_salt | 1.43680450 |
| 32 | MP0005360_urolithiasis | 1.38501235 |
| 33 | MP0001963_abnormal_hearing_physiology | 1.38367961 |
| 34 | MP0009379_abnormal_foot_pigmentation | 1.37427148 |
| 35 | MP0000372_irregular_coat_pigmentation | 1.34698373 |
| 36 | MP0000026_abnormal_inner_ear | 1.33331887 |
| 37 | MP0004043_abnormal_pH_regulation | 1.28786553 |
| 38 | MP0009764_decreased_sensitivity_to | 1.23583910 |
| 39 | MP0005253_abnormal_eye_physiology | 1.23078234 |
| 40 | MP0002735_abnormal_chemical_nociception | 1.16920909 |
| 41 | MP0002067_abnormal_sensory_capabilities | 1.13505830 |
| 42 | MP0005085_abnormal_gallbladder_physiolo | 1.12434982 |
| 43 | MP0003646_muscle_fatigue | 1.12333572 |
| 44 | MP0001764_abnormal_homeostasis | 1.11868708 |
| 45 | MP0005595_abnormal_vascular_smooth | 1.07985164 |
| 46 | MP0002938_white_spotting | 1.02785751 |
| 47 | MP0002282_abnormal_trachea_morphology | 1.02104254 |
| 48 | MP0000538_abnormal_urinary_bladder | 0.99053601 |
| 49 | MP0005310_abnormal_salivary_gland | 0.95800700 |
| 50 | MP0002736_abnormal_nociception_after | 0.94034517 |
| 51 | MP0002272_abnormal_nervous_system | 0.93174151 |
| 52 | MP0001765_abnormal_ion_homeostasis | 0.91906427 |
| 53 | MP0008961_abnormal_basal_metabolism | 0.91365905 |
| 54 | MP0002210_abnormal_sex_determination | 0.90259419 |
| 55 | MP0005671_abnormal_response_to | 0.89758872 |
| 56 | MP0005379_endocrine/exocrine_gland_phen | 0.89144656 |
| 57 | MP0003329_amyloid_beta_deposits | 0.88312426 |
| 58 | MP0002132_abnormal_respiratory_system | 0.87865315 |
| 59 | MP0002138_abnormal_hepatobiliary_system | 0.86876434 |
| 60 | MP0002557_abnormal_social/conspecific_i | 0.86841396 |
| 61 | MP0002064_seizures | 0.86256183 |
| 62 | MP0001664_abnormal_digestion | 0.85659469 |
| 63 | MP0002161_abnormal_fertility/fecundity | 0.82945797 |
| 64 | MP0002572_abnormal_emotion/affect_behav | 0.81947652 |
| 65 | MP0001501_abnormal_sleep_pattern | 0.81686089 |
| 66 | MP0009384_cardiac_valve_regurgitation | 0.80406689 |
| 67 | MP0002638_abnormal_pupillary_reflex | 0.78778142 |
| 68 | MP0002118_abnormal_lipid_homeostasis | 0.77529008 |
| 69 | MP0005386_behavior/neurological_phenoty | 0.77104462 |
| 70 | MP0004924_abnormal_behavior | 0.77104462 |
| 71 | MP0005332_abnormal_amino_acid | 0.76298806 |
| 72 | MP0001324_abnormal_eye_pigmentation | 0.75989077 |
| 73 | MP0001919_abnormal_reproductive_system | 0.75595339 |
| 74 | MP0003950_abnormal_plasma_membrane | 0.75061876 |
| 75 | MP0003638_abnormal_response/metabolism_ | 0.73878436 |
| 76 | MP0004133_heterotaxia | 0.73861986 |
| 77 | MP0000427_abnormal_hair_cycle | 0.73594623 |
| 78 | MP0004130_abnormal_muscle_cell | 0.73434929 |
| 79 | MP0003632_abnormal_nervous_system | 0.72872577 |
| 80 | MP0001970_abnormal_pain_threshold | 0.72844257 |
| 81 | MP0001529_abnormal_vocalization | 0.72003512 |
| 82 | MP0005167_abnormal_blood-brain_barrier | 0.67728029 |
| 83 | MP0005165_increased_susceptibility_to | 0.66307532 |
| 84 | MP0009278_abnormal_bone_marrow | 0.64752238 |
| 85 | MP0005083_abnormal_biliary_tract | 0.64419704 |
| 86 | MP0002063_abnormal_learning/memory/cond | 0.63590885 |
| 87 | MP0005084_abnormal_gallbladder_morpholo | 0.63482348 |
| 88 | MP0005195_abnormal_posterior_eye | 0.63340617 |
| 89 | MP0002733_abnormal_thermal_nociception | 0.63267225 |
| 90 | MP0002693_abnormal_pancreas_physiology | 0.62152706 |
| 91 | MP0005395_other_phenotype | 0.61988857 |
| 92 | MP0001851_eye_inflammation | 0.60656097 |
| 93 | MP0002136_abnormal_kidney_physiology | 0.60478495 |
| 94 | MP0002229_neurodegeneration | 0.60435416 |
| 95 | MP0004145_abnormal_muscle_electrophysio | 0.59666986 |
| 96 | MP0003959_abnormal_lean_body | 0.59413528 |
| 97 | MP0002277_abnormal_respiratory_mucosa | 0.59148738 |
| 98 | MP0005391_vision/eye_phenotype | 0.58437460 |
| 99 | MP0002928_abnormal_bile_duct | 0.58114492 |
| 100 | MP0000343_altered_response_to | 0.57767797 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Potter facies (HP:0002009) | 5.10297640 |
| 2 | Facial shape deformation (HP:0011334) | 5.10297640 |
| 3 | Chronic hepatic failure (HP:0100626) | 5.02337186 |
| 4 | Inability to walk (HP:0002540) | 4.86081590 |
| 5 | Molar tooth sign on MRI (HP:0002419) | 4.10482057 |
| 6 | Abnormality of midbrain morphology (HP:0002418) | 4.10482057 |
| 7 | Tubular atrophy (HP:0000092) | 4.04371928 |
| 8 | Concave nail (HP:0001598) | 4.00783749 |
| 9 | Renovascular hypertension (HP:0100817) | 3.75965352 |
| 10 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 3.67173285 |
| 11 | Confusion (HP:0001289) | 3.65126060 |
| 12 | Decreased central vision (HP:0007663) | 3.55583827 |
| 13 | Mutism (HP:0002300) | 3.52114232 |
| 14 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.51848676 |
| 15 | Absent/shortened dynein arms (HP:0200106) | 3.51848676 |
| 16 | Tubulointerstitial nephritis (HP:0001970) | 3.50353834 |
| 17 | True hermaphroditism (HP:0010459) | 3.45678811 |
| 18 | Progressive sensorineural hearing impairment (HP:0000408) | 3.44504493 |
| 19 | Birth length less than 3rd percentile (HP:0003561) | 3.37441756 |
| 20 | Hypoplastic iliac wings (HP:0002866) | 3.34235652 |
| 21 | Pancreatic cysts (HP:0001737) | 3.31630186 |
| 22 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 3.23592156 |
| 23 | Type II lissencephaly (HP:0007260) | 3.16870531 |
| 24 | Nephronophthisis (HP:0000090) | 3.05276712 |
| 25 | 11 pairs of ribs (HP:0000878) | 2.94331390 |
| 26 | Morphological abnormality of the inner ear (HP:0011390) | 2.91578617 |
| 27 | Cerebellar dysplasia (HP:0007033) | 2.82151697 |
| 28 | Progressive inability to walk (HP:0002505) | 2.74205929 |
| 29 | Brittle hair (HP:0002299) | 2.74147663 |
| 30 | Duplicated collecting system (HP:0000081) | 2.72005864 |
| 31 | Bronchomalacia (HP:0002780) | 2.60835282 |
| 32 | Stage 5 chronic kidney disease (HP:0003774) | 2.59857662 |
| 33 | Abnormal ciliary motility (HP:0012262) | 2.56907892 |
| 34 | Increased cerebral lipofuscin (HP:0011813) | 2.54980794 |
| 35 | Abnormality of the renal cortex (HP:0011035) | 2.53005427 |
| 36 | Hypoalbuminemia (HP:0003073) | 2.52362119 |
| 37 | Abnormal albumin level (HP:0012116) | 2.52362119 |
| 38 | Abnormality of dental color (HP:0011073) | 2.50380090 |
| 39 | Portal hypertension (HP:0001409) | 2.50171084 |
| 40 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.46594808 |
| 41 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.46594808 |
| 42 | Abolished electroretinogram (ERG) (HP:0000550) | 2.46237640 |
| 43 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.45395726 |
| 44 | Abnormality of alanine metabolism (HP:0010916) | 2.45395726 |
| 45 | Hyperalaninemia (HP:0003348) | 2.45395726 |
| 46 | Breast hypoplasia (HP:0003187) | 2.44753341 |
| 47 | Attenuation of retinal blood vessels (HP:0007843) | 2.44261332 |
| 48 | Amelogenesis imperfecta (HP:0000705) | 2.43827841 |
| 49 | Pancreatic fibrosis (HP:0100732) | 2.42682117 |
| 50 | Abnormality of the renal collecting system (HP:0004742) | 2.40456135 |
| 51 | Partial agenesis of the corpus callosum (HP:0001338) | 2.39371403 |
| 52 | Reticulocytopenia (HP:0001896) | 2.38704661 |
| 53 | Large for gestational age (HP:0001520) | 2.37125051 |
| 54 | Abnormality of the renal medulla (HP:0100957) | 2.34730271 |
| 55 | Abnormality of the pons (HP:0007361) | 2.32057894 |
| 56 | Severe muscular hypotonia (HP:0006829) | 2.31856584 |
| 57 | Abnormality of the hepatic vasculature (HP:0006707) | 2.29690214 |
| 58 | Morphological abnormality of the pyramidal tract (HP:0002062) | 2.22795319 |
| 59 | Progressive cerebellar ataxia (HP:0002073) | 2.22480429 |
| 60 | Non-midline cleft lip (HP:0100335) | 2.22268652 |
| 61 | Clumsiness (HP:0002312) | 2.21959647 |
| 62 | Tubulointerstitial abnormality (HP:0001969) | 2.20975904 |
| 63 | Redundant skin (HP:0001582) | 2.20920390 |
| 64 | Occipital encephalocele (HP:0002085) | 2.20620573 |
| 65 | Cystic liver disease (HP:0006706) | 2.19659247 |
| 66 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.17133047 |
| 67 | Morphological abnormality of the middle ear (HP:0008609) | 2.15550010 |
| 68 | Mesangial abnormality (HP:0001966) | 2.14024196 |
| 69 | Optic nerve hypoplasia (HP:0000609) | 2.10459825 |
| 70 | Thyroid-stimulating hormone excess (HP:0002925) | 2.09900354 |
| 71 | Hypophosphatemic rickets (HP:0004912) | 2.08085618 |
| 72 | Trigonocephaly (HP:0000243) | 2.05517421 |
| 73 | Polydipsia (HP:0001959) | 2.04587679 |
| 74 | Abnormal drinking behavior (HP:0030082) | 2.04587679 |
| 75 | Abnormal hair laboratory examination (HP:0003328) | 2.03306998 |
| 76 | Abnormality of DNA repair (HP:0003254) | 2.02975506 |
| 77 | Hyperkalemia (HP:0002153) | 2.01185009 |
| 78 | Abnormality of B cell number (HP:0010975) | 1.97346760 |
| 79 | Hypoplasia of the pons (HP:0012110) | 1.96147892 |
| 80 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.91139406 |
| 81 | Bilateral sensorineural hearing impairment (HP:0008619) | 1.91107264 |
| 82 | Congenital, generalized hypertrichosis (HP:0004540) | 1.91059823 |
| 83 | Congenital sensorineural hearing impairment (HP:0008527) | 1.90471233 |
| 84 | Progressive hearing impairment (HP:0001730) | 1.89635683 |
| 85 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.85911018 |
| 86 | Abnormal hemoglobin (HP:0011902) | 1.81897522 |
| 87 | Facial diplegia (HP:0001349) | 1.79362269 |
| 88 | Pendular nystagmus (HP:0012043) | 1.77984642 |
| 89 | Conical tooth (HP:0000698) | 1.77954865 |
| 90 | Abnormal number of erythroid precursors (HP:0012131) | 1.76817866 |
| 91 | Prominent supraorbital ridges (HP:0000336) | 1.76637200 |
| 92 | Increased circulating renin level (HP:0000848) | 1.75987448 |
| 93 | Increased corneal curvature (HP:0100692) | 1.74769905 |
| 94 | Keratoconus (HP:0000563) | 1.74769905 |
| 95 | Visual hallucinations (HP:0002367) | 1.74268241 |
| 96 | Hypoplastic ilia (HP:0000946) | 1.73813807 |
| 97 | Retrobulbar optic neuritis (HP:0100654) | 1.72672989 |
| 98 | Optic neuritis (HP:0100653) | 1.72672989 |
| 99 | Abnormal biliary tract physiology (HP:0012439) | 1.72184782 |
| 100 | Bile duct proliferation (HP:0001408) | 1.72184782 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ADRBK2 | 5.63850187 |
| 2 | PLK4 | 4.32454866 |
| 3 | WNK4 | 4.25339124 |
| 4 | PNCK | 3.87024884 |
| 5 | DAPK2 | 3.51378830 |
| 6 | IRAK1 | 3.46900792 |
| 7 | TSSK6 | 2.62646436 |
| 8 | TAOK3 | 2.39362958 |
| 9 | INSRR | 2.39025437 |
| 10 | TXK | 2.32210774 |
| 11 | STK39 | 2.26170442 |
| 12 | PIK3CG | 2.15210879 |
| 13 | ZAK | 1.91805314 |
| 14 | WEE1 | 1.88324274 |
| 15 | PTK2B | 1.77237891 |
| 16 | MAPKAPK3 | 1.76169748 |
| 17 | PLK2 | 1.74217655 |
| 18 | ADRBK1 | 1.71823325 |
| 19 | ACVR1B | 1.60311493 |
| 20 | MAPKAPK5 | 1.55390494 |
| 21 | MAPK15 | 1.53434148 |
| 22 | DYRK3 | 1.48573415 |
| 23 | FRK | 1.46806403 |
| 24 | GRK6 | 1.41578401 |
| 25 | BRD4 | 1.40909003 |
| 26 | OXSR1 | 1.39149078 |
| 27 | MAP3K9 | 1.32309284 |
| 28 | PIK3CA | 1.30506891 |
| 29 | WNK1 | 1.29634607 |
| 30 | TYRO3 | 1.28661021 |
| 31 | BMPR1B | 1.27939241 |
| 32 | BMPR2 | 1.27579318 |
| 33 | TGFBR1 | 1.27520049 |
| 34 | TIE1 | 1.23597924 |
| 35 | NEK2 | 1.23107462 |
| 36 | MUSK | 1.14256623 |
| 37 | GRK1 | 1.11276544 |
| 38 | MARK3 | 1.09021829 |
| 39 | IRAK3 | 1.05850505 |
| 40 | TRPM7 | 1.04723489 |
| 41 | NEK6 | 1.02518820 |
| 42 | CAMK1G | 0.96580691 |
| 43 | TLK1 | 0.93480444 |
| 44 | BCKDK | 0.89124649 |
| 45 | MELK | 0.88168056 |
| 46 | NTRK3 | 0.86244912 |
| 47 | LATS2 | 0.77759821 |
| 48 | MAP2K2 | 0.76087130 |
| 49 | IKBKB | 0.75508475 |
| 50 | CDK12 | 0.70854016 |
| 51 | STK11 | 0.70559030 |
| 52 | VRK1 | 0.64525718 |
| 53 | CHUK | 0.63495830 |
| 54 | PKN1 | 0.60784496 |
| 55 | PDK1 | 0.60261413 |
| 56 | SIK2 | 0.59075334 |
| 57 | STK3 | 0.57998887 |
| 58 | PINK1 | 0.54691134 |
| 59 | MAPK13 | 0.53494509 |
| 60 | MAP2K1 | 0.52456722 |
| 61 | CAMK1D | 0.52140505 |
| 62 | KIT | 0.52022316 |
| 63 | EEF2K | 0.51284139 |
| 64 | CSF1R | 0.51005401 |
| 65 | PRKCG | 0.49817585 |
| 66 | CDK3 | 0.47710449 |
| 67 | NUAK1 | 0.45921140 |
| 68 | PRKCE | 0.45122720 |
| 69 | RPS6KA6 | 0.45065713 |
| 70 | PIM1 | 0.43031067 |
| 71 | SGK2 | 0.42896171 |
| 72 | PRKCQ | 0.42812610 |
| 73 | PDPK1 | 0.41860188 |
| 74 | MATK | 0.40634304 |
| 75 | NLK | 0.36373514 |
| 76 | TNIK | 0.36285465 |
| 77 | RIPK4 | 0.35267198 |
| 78 | MAP2K6 | 0.30032090 |
| 79 | BMX | 0.29422261 |
| 80 | MAPK11 | 0.28527274 |
| 81 | PAK2 | 0.27447983 |
| 82 | CAMKK1 | 0.26727059 |
| 83 | BRSK2 | 0.24786505 |
| 84 | SGK223 | 0.22516908 |
| 85 | SGK494 | 0.22516908 |
| 86 | SYK | 0.22211363 |
| 87 | ERBB2 | 0.22019953 |
| 88 | TEC | 0.20901910 |
| 89 | MAPK1 | 0.20058220 |
| 90 | CDC7 | 0.19681640 |
| 91 | MAP4K1 | 0.19664082 |
| 92 | PRKCH | 0.18808136 |
| 93 | IGF1R | 0.18520595 |
| 94 | PRKAA1 | 0.18016569 |
| 95 | PRKACA | 0.17575198 |
| 96 | RPS6KA5 | 0.17090500 |
| 97 | MAPK3 | 0.17041505 |
| 98 | STK24 | 0.16923338 |
| 99 | PRKAA2 | 0.15065846 |
| 100 | PRKG1 | 0.15064722 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Butanoate metabolism_Homo sapiens_hsa00650 | 3.79598040 |
| 2 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 3.46117524 |
| 3 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 3.40378179 |
| 4 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 3.23840762 |
| 5 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 3.09622502 |
| 6 | Nitrogen metabolism_Homo sapiens_hsa00910 | 3.04732340 |
| 7 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.86670184 |
| 8 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 2.72924430 |
| 9 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 2.34802624 |
| 10 | Selenocompound metabolism_Homo sapiens_hsa00450 | 2.33703493 |
| 11 | ABC transporters_Homo sapiens_hsa02010 | 2.31145766 |
| 12 | Phototransduction_Homo sapiens_hsa04744 | 2.17586505 |
| 13 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 2.15384738 |
| 14 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.94231258 |
| 15 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.77443846 |
| 16 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.74860329 |
| 17 | Olfactory transduction_Homo sapiens_hsa04740 | 1.73607942 |
| 18 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.71486058 |
| 19 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.69519161 |
| 20 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.43312054 |
| 21 | Morphine addiction_Homo sapiens_hsa05032 | 1.41377371 |
| 22 | Taste transduction_Homo sapiens_hsa04742 | 1.41050577 |
| 23 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.37721186 |
| 24 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.35201140 |
| 25 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.28673422 |
| 26 | Nicotine addiction_Homo sapiens_hsa05033 | 1.28606228 |
| 27 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.27813858 |
| 28 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.26077327 |
| 29 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.21705267 |
| 30 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.20849703 |
| 31 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.17776953 |
| 32 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.17673845 |
| 33 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.17665114 |
| 34 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.14212729 |
| 35 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 1.14173712 |
| 36 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.13672042 |
| 37 | Peroxisome_Homo sapiens_hsa04146 | 1.06945805 |
| 38 | Retinol metabolism_Homo sapiens_hsa00830 | 1.06195918 |
| 39 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.04871091 |
| 40 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.04141935 |
| 41 | Sulfur relay system_Homo sapiens_hsa04122 | 1.03872521 |
| 42 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 1.00629732 |
| 43 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.00591698 |
| 44 | Bile secretion_Homo sapiens_hsa04976 | 0.93845071 |
| 45 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.88828311 |
| 46 | Circadian entrainment_Homo sapiens_hsa04713 | 0.86739267 |
| 47 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.82544147 |
| 48 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.80083701 |
| 49 | GABAergic synapse_Homo sapiens_hsa04727 | 0.76230658 |
| 50 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.75328424 |
| 51 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.74074198 |
| 52 | Mineral absorption_Homo sapiens_hsa04978 | 0.72350405 |
| 53 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.71352400 |
| 54 | Basal transcription factors_Homo sapiens_hsa03022 | 0.70315849 |
| 55 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.70073890 |
| 56 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.68573931 |
| 57 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.66705101 |
| 58 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.66572531 |
| 59 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.66496909 |
| 60 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.66364477 |
| 61 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.64601436 |
| 62 | Homologous recombination_Homo sapiens_hsa03440 | 0.62096183 |
| 63 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.60225675 |
| 64 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.59732951 |
| 65 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.58756396 |
| 66 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.58362470 |
| 67 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.57124066 |
| 68 | Platelet activation_Homo sapiens_hsa04611 | 0.56606770 |
| 69 | Ribosome_Homo sapiens_hsa03010 | 0.55265455 |
| 70 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.54088300 |
| 71 | Insulin secretion_Homo sapiens_hsa04911 | 0.52186021 |
| 72 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.50247056 |
| 73 | Salivary secretion_Homo sapiens_hsa04970 | 0.47686278 |
| 74 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.47611424 |
| 75 | Melanoma_Homo sapiens_hsa05218 | 0.46582985 |
| 76 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.46107853 |
| 77 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.45077750 |
| 78 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.43673599 |
| 79 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.42384991 |
| 80 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.41725915 |
| 81 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.41538441 |
| 82 | Histidine metabolism_Homo sapiens_hsa00340 | 0.41236186 |
| 83 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.41034077 |
| 84 | Long-term depression_Homo sapiens_hsa04730 | 0.39694856 |
| 85 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.39600623 |
| 86 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.39496236 |
| 87 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.36656673 |
| 88 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.36285336 |
| 89 | Legionellosis_Homo sapiens_hsa05134 | 0.35868632 |
| 90 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.32231858 |
| 91 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.31269127 |
| 92 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.31237180 |
| 93 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.27783862 |
| 94 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.27377091 |
| 95 | Lysosome_Homo sapiens_hsa04142 | 0.27028864 |
| 96 | Metabolic pathways_Homo sapiens_hsa01100 | 0.26965860 |
| 97 | Bladder cancer_Homo sapiens_hsa05219 | 0.26616868 |
| 98 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.25697968 |
| 99 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.22146047 |
| 100 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.22102462 |

