GYS1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1muscle filament sliding (GO:0030049)9.45584803
2actin-myosin filament sliding (GO:0033275)9.45584803
3actin-mediated cell contraction (GO:0070252)7.76461593
4regulation of skeletal muscle contraction (GO:0014819)7.71488104
5sarcomere organization (GO:0045214)7.67871069
6plasma membrane repair (GO:0001778)7.17002295
7myofibril assembly (GO:0030239)6.47032335
8cardiac myofibril assembly (GO:0055003)6.14433815
9negative regulation of potassium ion transmembrane transporter activity (GO:1901017)6.12587395
10skeletal muscle contraction (GO:0003009)5.99419179
11tricarboxylic acid cycle (GO:0006099)5.89222796
12actin filament-based movement (GO:0030048)5.88207356
13sarcoplasmic reticulum calcium ion transport (GO:0070296)5.86310726
14regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)5.59204004
15carnitine shuttle (GO:0006853)5.53596917
16positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)5.50315425
17negative regulation of potassium ion transmembrane transport (GO:1901380)5.32026769
18striated muscle contraction (GO:0006941)5.30489635
19actomyosin structure organization (GO:0031032)5.12008097
20skeletal muscle adaptation (GO:0043501)4.99137997
21cardiac muscle contraction (GO:0060048)4.94388185
22regulation of acyl-CoA biosynthetic process (GO:0050812)4.93705414
23cardiac muscle cell development (GO:0055013)4.85435577
24regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)4.84086437
25muscle cell fate commitment (GO:0042693)4.81527213
26regulation of cofactor metabolic process (GO:0051193)4.81028106
27regulation of coenzyme metabolic process (GO:0051196)4.81028106
28fatty acid transmembrane transport (GO:1902001)4.70132157
29cardiac cell development (GO:0055006)4.56144810
30regulation of sequestering of triglyceride (GO:0010889)4.31642747
31regulation of relaxation of muscle (GO:1901077)4.16077389
32NADH metabolic process (GO:0006734)4.15620615
33regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)4.14519302
34regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)4.10634836
35muscle contraction (GO:0006936)4.07220286
36carnitine transmembrane transport (GO:1902603)4.01595934
37cardiac muscle tissue morphogenesis (GO:0055008)4.00527831
38response to stimulus involved in regulation of muscle adaptation (GO:0014874)4.00309264
39heart process (GO:0003015)3.96697468
40heart contraction (GO:0060047)3.96697468
41cell-substrate adherens junction assembly (GO:0007045)3.94354026
42focal adhesion assembly (GO:0048041)3.94354026
43negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.87489340
44regulation of actin filament-based movement (GO:1903115)3.87357071
45regulation of cell communication by electrical coupling (GO:0010649)3.86249754
46skeletal muscle fiber development (GO:0048741)3.85715198
47pyrimidine ribonucleoside catabolic process (GO:0046133)3.83953841
48gluconeogenesis (GO:0006094)3.76950191
49skeletal muscle tissue regeneration (GO:0043403)3.76710330
50muscle tissue morphogenesis (GO:0060415)3.75740720
51creatine metabolic process (GO:0006600)3.70752609
52muscle system process (GO:0003012)3.67372979
53cell-substrate junction assembly (GO:0007044)3.66112401
54striated muscle atrophy (GO:0014891)3.65848717
55heart trabecula formation (GO:0060347)3.65026340
56response to muscle activity (GO:0014850)3.63959285
57glycogen catabolic process (GO:0005980)3.62932339
58regulation of the force of heart contraction (GO:0002026)3.62570431
59amino-acid betaine transport (GO:0015838)3.62384335
60carnitine transport (GO:0015879)3.62384335
61striated muscle cell development (GO:0055002)3.60934668
62striated muscle adaptation (GO:0014888)3.59457881
63regulation of sulfur metabolic process (GO:0042762)3.58531131
64regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.58150889
65adherens junction assembly (GO:0034333)3.57889693
66adult heart development (GO:0007512)3.56860186
67cardiac muscle hypertrophy (GO:0003300)3.56548209
68protein hydroxylation (GO:0018126)3.55426214
69skeletal muscle tissue development (GO:0007519)3.54869986
70cytidine metabolic process (GO:0046087)3.50805299
71cytidine catabolic process (GO:0006216)3.50805299
72cytidine deamination (GO:0009972)3.50805299
73striated muscle hypertrophy (GO:0014897)3.49090612
74muscle fiber development (GO:0048747)3.47972748
75regulation of striated muscle contraction (GO:0006942)3.47908199
76positive regulation of myotube differentiation (GO:0010831)3.47844015
77hexose biosynthetic process (GO:0019319)3.43940172
78oxidative phosphorylation (GO:0006119)3.42310902
79negative regulation of cell size (GO:0045792)3.41095811
80ventricular cardiac muscle cell action potential (GO:0086005)3.36432349
81ventricular cardiac muscle tissue morphogenesis (GO:0055010)3.34069533
82glucan catabolic process (GO:0009251)3.33363648
83response to inactivity (GO:0014854)3.31895226
84negative regulation of necroptotic process (GO:0060546)3.29262952
85regulation of fatty acid oxidation (GO:0046320)3.25176877
86muscle organ morphogenesis (GO:0048644)3.24570321
87cellular polysaccharide catabolic process (GO:0044247)3.23409411
88IMP metabolic process (GO:0046040)3.23389864
89oxaloacetate metabolic process (GO:0006107)3.21739645
90myoblast fusion (GO:0007520)3.21121903
91regulation of sarcomere organization (GO:0060297)3.18540768
92monosaccharide biosynthetic process (GO:0046364)3.17446754
93lipid particle organization (GO:0034389)3.16047745
94muscle organ development (GO:0007517)3.15501564
95mitochondrial fusion (GO:0008053)3.14822317
96muscle cell development (GO:0055001)3.13626113
972-oxoglutarate metabolic process (GO:0006103)3.12615713
98myotube cell development (GO:0014904)3.12311703
99hemidesmosome assembly (GO:0031581)3.11101223
100fructose metabolic process (GO:0006000)3.10924383
101regulation of membrane repolarization (GO:0060306)3.10660765
102muscle structure development (GO:0061061)3.09874575
103muscle adaptation (GO:0043500)3.06852877
104muscle hypertrophy (GO:0014896)3.06485973
105syncytium formation by plasma membrane fusion (GO:0000768)3.06287910
106bundle of His cell to Purkinje myocyte communication (GO:0086069)3.05976067
107regulation of myotube differentiation (GO:0010830)3.05634850
108tricarboxylic acid metabolic process (GO:0072350)3.04545507
1094-hydroxyproline metabolic process (GO:0019471)3.03618745
110polysaccharide catabolic process (GO:0000272)3.03307863
111peptidyl-proline hydroxylation (GO:0019511)3.00933678
112valine metabolic process (GO:0006573)3.00762297
113glycolytic process (GO:0006096)2.97090653
114muscle cell cellular homeostasis (GO:0046716)2.96641803
115regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.96544599
116muscle atrophy (GO:0014889)2.96010007
117negative regulation of muscle hypertrophy (GO:0014741)2.92969823
118positive regulation of calcium ion transmembrane transporter activity (GO:1901021)2.89602018
119* glycogen biosynthetic process (GO:0005978)2.89088919
120* glucan biosynthetic process (GO:0009250)2.89088919
121epithelial cell-cell adhesion (GO:0090136)2.88929090
122regulation of p38MAPK cascade (GO:1900744)2.88155101
123regulation of myoblast differentiation (GO:0045661)2.85625409
124regulation of skeletal muscle cell differentiation (GO:2001014)2.84959569
125basement membrane organization (GO:0071711)2.83045060
126Golgi transport vesicle coating (GO:0048200)2.76908709
127COPI coating of Golgi vesicle (GO:0048205)2.76908709
128barbed-end actin filament capping (GO:0051016)2.73993179
129* glycogen metabolic process (GO:0005977)2.72673755
130cardiac muscle adaptation (GO:0014887)2.70065687
131cardiac muscle hypertrophy in response to stress (GO:0014898)2.70065687
132muscle hypertrophy in response to stress (GO:0003299)2.70065687
133positive regulation of myoblast differentiation (GO:0045663)2.67913541
134apoptotic process involved in morphogenesis (GO:0060561)2.66168031

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1PPARG_19300518_ChIP-PET_3T3-L1_Mouse7.30693329
2TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse4.17751500
3BP1_19119308_ChIP-ChIP_Hs578T_Human3.69600628
4RARG_19884340_ChIP-ChIP_MEFs_Mouse3.43784846
5TP63_17297297_ChIP-ChIP_HaCaT_Human2.85763449
6NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.71635349
7CLOCK_20551151_ChIP-Seq_293T_Human2.70591877
8* TBX20_22328084_ChIP-Seq_HEART_Mouse2.60952855
9* TBX20_22080862_ChIP-Seq_HEART_Mouse2.60952855
10ESRRB_18555785_ChIP-Seq_MESCs_Mouse2.54266884
11ZNF263_19887448_ChIP-Seq_K562_Human2.49701206
12EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.37328673
13HIF1A_21447827_ChIP-Seq_MCF-7_Human2.36694910
14TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.33326490
15ESR1_20079471_ChIP-ChIP_T-47D_Human2.18638915
16MEF2A_21415370_ChIP-Seq_HL-1_Mouse2.06452131
17EP300_21415370_ChIP-Seq_HL-1_Mouse1.99007611
18TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.94720851
19RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.93445169
20RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.91962495
21ELK3_25401928_ChIP-Seq_HUVEC_Human1.89278325
22* NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.88661095
23STAT3_1855785_ChIP-Seq_MESCs_Mouse1.88542565
24* GATA4_21415370_ChIP-Seq_HL-1_Mouse1.88311545
25ATF3_27146783_Chip-Seq_COLON_Human1.77982880
26VDR_21846776_ChIP-Seq_THP-1_Human1.75964616
27MYC_22102868_ChIP-Seq_BL_Human1.69336668
28KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.68345201
29FOXM1_23109430_ChIP-Seq_U2OS_Human1.67567978
30TET1_21451524_ChIP-Seq_MESCs_Mouse1.66570146
31BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.62342478
32KDM2B_26808549_Chip-Seq_K562_Human1.61098591
33RACK7_27058665_Chip-Seq_MCF-7_Human1.59946630
34KDM2B_26808549_Chip-Seq_DND41_Human1.56892572
35* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.56219249
36ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.55095847
37ERG_21242973_ChIP-ChIP_JURKAT_Human1.52561883
38TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.52420294
39CTCF_27219007_Chip-Seq_ERYTHROID_Human1.51748445
40KDM2B_26808549_Chip-Seq_SUP-B15_Human1.50221771
41EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.49654963
42EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.49413479
43ZFP281_18757296_ChIP-ChIP_E14_Mouse1.48059784
44EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.47648155
45* SA1_27219007_Chip-Seq_ERYTHROID_Human1.45755053
46STAT6_21828071_ChIP-Seq_BEAS2B_Human1.45413820
47ESR2_21235772_ChIP-Seq_MCF-7_Human1.40162208
48EGR1_19374776_ChIP-ChIP_THP-1_Human1.40112033
49CTCF_27219007_Chip-Seq_Bcells_Human1.40075911
50ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.39955925
51LXR_22292898_ChIP-Seq_THP-1_Human1.38586021
52SRY_22984422_ChIP-ChIP_TESTIS_Rat1.38378313
53SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.38233170
54SMC4_20622854_ChIP-Seq_HELA_Human1.37771400
55ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.37695202
56CIITA_25753668_ChIP-Seq_RAJI_Human1.35880679
57NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.35737746
58TRIM28_21343339_ChIP-Seq_HEK293_Human1.32265889
59THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.32229682
60TCF7_22412390_ChIP-Seq_EML_Mouse1.30828639
61DNAJC2_21179169_ChIP-ChIP_NT2_Human1.30742710
62TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.29700535
63STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.28685211
64SMC3_22415368_ChIP-Seq_MEFs_Mouse1.28631188
65NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.27532549
66ESR1_21235772_ChIP-Seq_MCF-7_Human1.26342074
67KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.25915383
68UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.25644752
69E2F7_22180533_ChIP-Seq_HELA_Human1.24735651
70KDM2B_26808549_Chip-Seq_JURKAT_Human1.23903971
71CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.23530120
72CREB1_26743006_Chip-Seq_LNCaP_Human1.23391253
73P300_27058665_Chip-Seq_ZR-75-30cells_Human1.23378806
74CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.21507242
75PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.21423232
76SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.20784907
77KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.20640731
78FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.20311937
79MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.19575004
80STAT3_19079543_ChIP-ChIP_MESCs_Mouse1.18313878
81ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.16986034
82ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.16799697
83HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.14407167
84POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.13904386
85P68_20966046_ChIP-Seq_HELA_Human1.12923629
86CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.11694401
87CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.09949357
88KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.09725107
89CTCF_26484167_Chip-Seq_Bcells_Mouse1.08609084
90NFIB_24661679_ChIP-Seq_LUNG_Mouse1.08394899
91ELF1_20517297_ChIP-Seq_JURKAT_Human1.08203216
92TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.07553386
93MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.07427803
94PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.07398437
95NANOG_18555785_ChIP-Seq_MESCs_Mouse1.07319660
96P63_26484246_Chip-Seq_KERATINOCYTES_Human1.06509493
97MAF_26560356_Chip-Seq_TH1_Human1.05648795
98PPAR_26484153_Chip-Seq_NCI-H1993_Human1.03869951
99TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.02941407
100MAF_26560356_Chip-Seq_TH2_Human1.02264098
101DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.02248085
102PPARA_22158963_ChIP-Seq_LIVER_Mouse1.02166410
103SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.02053364
104PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.00251423
105BCL6_27268052_Chip-Seq_Bcells_Human1.00053352
106CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.99780680
107NCOR1_26117541_ChIP-Seq_K562_Human0.99527281
108SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.99474502
109GATA1_19941827_ChIP-Seq_MEL_Mouse0.99320287
110TP53_20018659_ChIP-ChIP_R1E_Mouse0.99255955
111UBF1/2_26484160_Chip-Seq_HMECs_Human0.98097629
112YY1_22570637_ChIP-Seq_MALME-3M_Human0.97626284
113MYC_18555785_ChIP-Seq_MESCs_Mouse0.97386389
114CTCF_21964334_ChIP-Seq_BJAB-B_Human0.96514919
115CTCF_21964334_Chip-Seq_Bcells_Human0.96353860
116WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.95766680
117BRD4_27068464_Chip-Seq_AML-cells_Mouse0.95073943
118ESR1_15608294_ChIP-ChIP_MCF-7_Human0.94706092
119* TP53_22127205_ChIP-Seq_IMR90_Human0.94652710
120ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.93450423
121TP63_22573176_ChIP-Seq_HFKS_Human0.93027839
122KLF4_18555785_ChIP-Seq_MESCs_Mouse0.92771649
123SPI1_20517297_ChIP-Seq_HL60_Human0.91625011
124CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.91335531
125HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.90159885
126* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.89147670
127RUNX1_27514584_Chip-Seq_MCF-7_Human0.88837861
128NANOG_21062744_ChIP-ChIP_HESCs_Human0.88688254
129SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.88583372
130SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.88333599
131NELFA_20434984_ChIP-Seq_ESCs_Mouse0.87028598
132TBX5_21415370_ChIP-Seq_HL-1_Mouse0.87015656
133SMC1_22415368_ChIP-Seq_MEFs_Mouse0.86955070
134MYB_21317192_ChIP-Seq_ERMYB_Mouse0.85221827
135KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.85212794
136BCOR_27268052_Chip-Seq_Bcells_Human0.84042649

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003646_muscle_fatigue5.45324070
2MP0002837_dystrophic_cardiac_calcinosis4.93399332
3MP0000751_myopathy4.82104955
4MP0000749_muscle_degeneration4.47295605
5MP0004084_abnormal_cardiac_muscle4.08709188
6MP0004036_abnormal_muscle_relaxation3.66542406
7MP0004145_abnormal_muscle_electrophysio3.55326250
8MP0005451_abnormal_body_composition3.43937402
9MP0004087_abnormal_muscle_fiber3.23377173
10MP0000750_abnormal_muscle_regeneration3.17207728
11MP0004130_abnormal_muscle_cell3.00740166
12* MP0002106_abnormal_muscle_physiology2.96691439
13MP0005330_cardiomyopathy2.83393500
14MP0000759_abnormal_skeletal_muscle2.74871649
15MP0004215_abnormal_myocardial_fiber2.71863805
16MP0000747_muscle_weakness2.71013509
17MP0005620_abnormal_muscle_contractility2.66125692
18MP0002269_muscular_atrophy2.63843146
19* MP0005369_muscle_phenotype2.44035072
20MP0002972_abnormal_cardiac_muscle2.32858469
21MP0004233_abnormal_muscle_weight2.27876350
22MP0005666_abnormal_adipose_tissue2.19064881
23MP0005670_abnormal_white_adipose2.19034167
24MP0003705_abnormal_hypodermis_morpholog2.17388043
25MP0008438_abnormal_cutaneous_collagen2.17346252
26* MP0010630_abnormal_cardiac_muscle2.11468673
27MP0008775_abnormal_heart_ventricle2.07106897
28MP0004185_abnormal_adipocyte_glucose2.05869535
29* MP0001544_abnormal_cardiovascular_syste1.91819767
30* MP0005385_cardiovascular_system_phenoty1.91819767
31MP0003221_abnormal_cardiomyocyte_apopto1.91142791
32MP0000733_abnormal_muscle_development1.88021654
33MP0006138_congestive_heart_failure1.72667378
34MP0004484_altered_response_of1.69922271
35MP0003828_pulmonary_edema1.69426974
36MP0004858_abnormal_nervous_system1.66048435
37MP0003137_abnormal_impulse_conducting1.60881450
38MP0005375_adipose_tissue_phenotype1.60108900
39MP0003566_abnormal_cell_adhesion1.58255564
40MP0005275_abnormal_skin_tensile1.56467570
41MP0002332_abnormal_exercise_endurance1.50548593
42MP0006036_abnormal_mitochondrial_physio1.50451657
43MP0001661_extended_life_span1.45320380
44MP0003279_aneurysm1.36468667
45MP0002108_abnormal_muscle_morphology1.36120911
46MP0003950_abnormal_plasma_membrane1.34451706
47MP0002971_abnormal_brown_adipose1.26474067
48MP0000343_altered_response_to1.23177781
49MP0000013_abnormal_adipose_tissue1.08521110
50MP0000003_abnormal_adipose_tissue1.05679152
51* MP0000266_abnormal_heart_morphology1.03394736
52MP0004272_abnormal_basement_membrane1.03377813
53MP0002127_abnormal_cardiovascular_syste1.02281741
54MP0009780_abnormal_chondrocyte_physiolo1.01443634
55MP0000678_abnormal_parathyroid_gland1.00522329
56MP0005257_abnormal_intraocular_pressure1.00232305
57MP0008260_abnormal_autophagy0.98299117
58MP0005058_abnormal_lysosome_morphology0.96811848
59MP0002877_abnormal_melanocyte_morpholog0.95611897
60MP0005623_abnormal_meninges_morphology0.95174001
61MP0004510_myositis0.94031156
62MP0004085_abnormal_heartbeat0.90993343
63* MP0003567_abnormal_fetal_cardiomyocyte0.87695684
64MP0002234_abnormal_pharynx_morphology0.86411474
65MP0000579_abnormal_nail_morphology0.84896555
66MP0002249_abnormal_larynx_morphology0.82993390
67MP0010352_gastrointestinal_tract_polyps0.80919376
68MP0005266_abnormal_metabolism0.79953877
69MP0005503_abnormal_tendon_morphology0.78986170
70MP0009115_abnormal_fat_cell0.77599446
71MP0001299_abnormal_eye_distance/0.76281635
72MP0009840_abnormal_foam_cell0.75712769
73MP0005076_abnormal_cell_differentiation0.73875080
74MP0005409_darkened_coat_color0.73247484
75MP0001348_abnormal_lacrimal_gland0.69790166
76MP0000467_abnormal_esophagus_morphology0.68655183
77MP0003453_abnormal_keratinocyte_physiol0.68313403
78MP0003941_abnormal_skin_development0.67683719
79* MP0002128_abnormal_blood_circulation0.67533028
80MP0006035_abnormal_mitochondrial_morpho0.65586520
81MP0003191_abnormal_cellular_cholesterol0.64081011
82MP0003045_fibrosis0.63470838
83MP0005334_abnormal_fat_pad0.61965187
84MP0002796_impaired_skin_barrier0.61894506
85MP0002970_abnormal_white_adipose0.61596032
86MP0003984_embryonic_growth_retardation0.61278589
87MP0001958_emphysema0.60283777
88MP0002088_abnormal_embryonic_growth/wei0.59912814
89MP0002925_abnormal_cardiovascular_devel0.59717180
90MP0010030_abnormal_orbit_morphology0.58643788
91MP0005023_abnormal_wound_healing0.58172706
92MP0004197_abnormal_fetal_growth/weight/0.58065087
93MP0000372_irregular_coat_pigmentation0.57815896
94MP0008961_abnormal_basal_metabolism0.56454489
95MP0005165_increased_susceptibility_to0.54426862
96MP0000767_abnormal_smooth_muscle0.54284678
97MP0006054_spinal_hemorrhage0.50635237
98* MP0001614_abnormal_blood_vessel0.49875011
99MP0010234_abnormal_vibrissa_follicle0.49135209
100MP0010368_abnormal_lymphatic_system0.48800128
101MP0002114_abnormal_axial_skeleton0.48365189
102MP0001849_ear_inflammation0.47100088
103MP0000534_abnormal_ureter_morphology0.46166022
104MP0005380_embryogenesis_phenotype0.45750451
105MP0001672_abnormal_embryogenesis/_devel0.45750451
106MP0005501_abnormal_skin_physiology0.44910014
107MP0009384_cardiac_valve_regurgitation0.44709768
108MP0003948_abnormal_gas_homeostasis0.44514341
109MP0002060_abnormal_skin_morphology0.43751446
110MP0009278_abnormal_bone_marrow0.42969944
111MP0003385_abnormal_body_wall0.42041393
112MP0009672_abnormal_birth_weight0.40511211
113MP0001730_embryonic_growth_arrest0.40341616
114MP0001853_heart_inflammation0.39675214
115MP0003959_abnormal_lean_body0.39091391
116MP0005452_abnormal_adipose_tissue0.38338142
117MP0001879_abnormal_lymphatic_vessel0.37856016
118* MP0002078_abnormal_glucose_homeostasis0.37443970
119MP0002896_abnormal_bone_mineralization0.37199005
120MP0000762_abnormal_tongue_morphology0.37189236
121MP0001784_abnormal_fluid_regulation0.36694742
122MP0003091_abnormal_cell_migration0.36280004
123MP0000428_abnormal_craniofacial_morphol0.35961806
124MP0009250_abnormal_appendicular_skeleto0.35791575
125MP0001697_abnormal_embryo_size0.34763235
126MP0000230_abnormal_systemic_arterial0.34310779
127MP0008770_decreased_survivor_rate0.33579959

Predicted human phenotypes

RankGene SetZ-score
1Muscle fiber inclusion bodies (HP:0100299)7.15287733
2Exercise-induced muscle cramps (HP:0003710)7.13111638
3Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)6.90075148
4Exercise-induced myalgia (HP:0003738)6.80695512
5Type 1 muscle fiber predominance (HP:0003803)6.70476750
6Nemaline bodies (HP:0003798)6.30249495
7Calf muscle hypertrophy (HP:0008981)5.57750419
8Muscle hypertrophy of the lower extremities (HP:0008968)5.56853092
9Muscle fiber splitting (HP:0003555)5.55188490
10Myoglobinuria (HP:0002913)5.31479753
11Increased connective tissue (HP:0009025)5.02257827
12Hyporeflexia of lower limbs (HP:0002600)4.96423143
13Distal arthrogryposis (HP:0005684)4.93402301
14Difficulty running (HP:0009046)4.91257998
15Sudden death (HP:0001699)4.91237274
16Rhabdomyolysis (HP:0003201)4.54074708
17Abnormality of the calf musculature (HP:0001430)4.50112099
18EMG: myopathic abnormalities (HP:0003458)4.44679694
19Abnormality of the left ventricular outflow tract (HP:0011103)4.41892601
20Subaortic stenosis (HP:0001682)4.41892601
21Ulnar deviation of the wrist (HP:0003049)4.28645084
22Myopathic facies (HP:0002058)4.26706805
23Round ear (HP:0100830)4.17908669
24Ventricular tachycardia (HP:0004756)4.10012506
25Abnormality of skeletal muscle fiber size (HP:0012084)3.88441030
26Increased variability in muscle fiber diameter (HP:0003557)3.63240396
27Muscle stiffness (HP:0003552)3.61943191
28Asymmetric septal hypertrophy (HP:0001670)3.61403042
29Myotonia (HP:0002486)3.58735834
30Calcaneovalgus deformity (HP:0001848)3.57338716
31Lipoatrophy (HP:0100578)3.54778054
32Difficulty climbing stairs (HP:0003551)3.54007994
33Neck muscle weakness (HP:0000467)3.32922837
34Deformed tarsal bones (HP:0008119)3.27311804
35Right ventricular cardiomyopathy (HP:0011663)3.21507795
36Atrial fibrillation (HP:0005110)2.95741757
37Mildly elevated creatine phosphokinase (HP:0008180)2.92371373
38Dilated cardiomyopathy (HP:0001644)2.90623317
39Absent phalangeal crease (HP:0006109)2.82549870
40Distal lower limb muscle weakness (HP:0009053)2.77523779
41Primary atrial arrhythmia (HP:0001692)2.75235921
42Areflexia of lower limbs (HP:0002522)2.75165137
43Spinal rigidity (HP:0003306)2.70880541
44Frequent falls (HP:0002359)2.69625435
45Rimmed vacuoles (HP:0003805)2.68347076
46Supraventricular tachycardia (HP:0004755)2.66661647
47Scapular winging (HP:0003691)2.65905675
48Supraventricular arrhythmia (HP:0005115)2.65060530
49Slender build (HP:0001533)2.56849956
50Palpitations (HP:0001962)2.56458704
51Abnormality of the calcaneus (HP:0008364)2.51685007
52Centrally nucleated skeletal muscle fibers (HP:0003687)2.51535710
53Generalized muscle weakness (HP:0003324)2.50330263
54Malignant hyperthermia (HP:0002047)2.49657926
55EMG: neuropathic changes (HP:0003445)2.40901497
56Ventricular arrhythmia (HP:0004308)2.37793803
57Bundle branch block (HP:0011710)2.37182759
58Popliteal pterygium (HP:0009756)2.37036343
59Limb-girdle muscle atrophy (HP:0003797)2.32792574
60Achilles tendon contracture (HP:0001771)2.31342626
61Facial diplegia (HP:0001349)2.30052059
62Abnormal finger flexion creases (HP:0006143)2.24962098
63Distal lower limb amyotrophy (HP:0008944)2.24552942
64Hypoplastic ischia (HP:0003175)2.23460851
65Limb-girdle muscle weakness (HP:0003325)2.22265785
66Fetal akinesia sequence (HP:0001989)2.21534971
67Gowers sign (HP:0003391)2.20551611
68Ragged-red muscle fibers (HP:0003200)2.19436489
69Muscular dystrophy (HP:0003560)2.18852859
70Proximal amyotrophy (HP:0007126)2.12913646
71Pelvic girdle muscle weakness (HP:0003749)2.12464790
72Prolonged QT interval (HP:0001657)2.10404187
73Hip contracture (HP:0003273)2.05706255
74Ankle contracture (HP:0006466)2.04690359
75Abnormality of the musculature of the pelvis (HP:0001469)2.03660877
76Abnormality of the hip-girdle musculature (HP:0001445)2.03660877
77Abnormality of the shoulder girdle musculature (HP:0001435)2.02616298
78Easy fatigability (HP:0003388)2.00129422
79Abnormality of the Achilles tendon (HP:0005109)1.99365842
80Protrusio acetabuli (HP:0003179)1.97941891
81Generalized amyotrophy (HP:0003700)1.97842455
82Progressive muscle weakness (HP:0003323)1.97828170
83Heart block (HP:0012722)1.97763515
84Abnormality of the neuromuscular junction (HP:0003398)1.96658172
85Fatigable weakness (HP:0003473)1.96658172
86Syncope (HP:0001279)1.95199519
87Shoulder girdle muscle weakness (HP:0003547)1.95193842
88Abnormal atrioventricular conduction (HP:0005150)1.94006588
89Atrioventricular block (HP:0001678)1.90779813
90Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.89130190
91Waddling gait (HP:0002515)1.88987852
92Weak cry (HP:0001612)1.88534302
93Abnormality of the ischium (HP:0003174)1.87369817
94Fragile skin (HP:0001030)1.85394049
95Conjunctival hamartoma (HP:0100780)1.83577805
96Bulbar palsy (HP:0001283)1.82420754
97Pterygium (HP:0001059)1.80788635
98Thin ribs (HP:0000883)1.78091443
99Broad metatarsal (HP:0001783)1.75422150
100Respiratory insufficiency due to muscle weakness (HP:0002747)1.73827637
101Increased muscle lipid content (HP:0009058)1.71827580
102Abnormality of placental membranes (HP:0011409)1.69924537
103Amniotic constriction ring (HP:0009775)1.69924537
104Cerebral aneurysm (HP:0004944)1.67624903
105Metatarsus adductus (HP:0001840)1.67255374
106Premature rupture of membranes (HP:0001788)1.64763284
107Wrist flexion contracture (HP:0001239)1.64580340
108Abnormality of the foot musculature (HP:0001436)1.64321502
109Stridor (HP:0010307)1.62866329
110Atrophic scars (HP:0001075)1.61515326
111Congenital hip dislocation (HP:0001374)1.61145141
112Aplasia of the musculature (HP:0100854)1.59830043
113Muscle fiber atrophy (HP:0100295)1.56734910
114Trismus (HP:0000211)1.56690746
115Hepatic necrosis (HP:0002605)1.56356935
116Foot dorsiflexor weakness (HP:0009027)1.55904241
117Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.55896983
118Abnormality of alanine metabolism (HP:0010916)1.55896983
119Hyperalaninemia (HP:0003348)1.55896983
120Abnormality of the tricuspid valve (HP:0001702)1.55873369
121Lower limb amyotrophy (HP:0007210)1.55697898
122Palmoplantar keratoderma (HP:0000982)1.54667358
123Breech presentation (HP:0001623)1.53473797
124Hypoplastic heart (HP:0001961)1.51549170
125Reduced subcutaneous adipose tissue (HP:0003758)1.48746186
126Back pain (HP:0003418)1.47293659

Predicted kinase interactions (KEA)

RankGene SetZ-score
1OBSCN6.08161462
2TTN6.04581710
3TRIB34.32787484
4PKN23.79240882
5PHKG13.59998361
6PHKG23.59998361
7NEK13.00281279
8SMG12.88656082
9PDK32.76789923
10PDK42.76789923
11ICK2.17929449
12DMPK2.17083702
13BCKDK2.12455866
14MAP2K32.07410240
15PIK3CG2.00407909
16PRPF4B1.93939016
17LMTK21.72127247
18MYLK1.64760054
19IRAK31.61889134
20PDK21.56843625
21FLT31.56741296
22MAPKAPK31.54511595
23EEF2K1.54129330
24NME11.51943807
25PIK3CA1.51776578
26RIPK11.39870506
27STK241.32105194
28ILK1.23855784
29ERN11.20117933
30SIK11.19191694
31MAP3K131.18134556
32TRPM71.16217875
33ARAF1.14849010
34MAP3K71.09052199
35LATS21.05644600
36PDGFRA1.03527509
37MUSK1.02894805
38CAMK1D1.01313650
39FGFR40.99944518
40PINK10.99463542
41PRKD30.97849724
42ZAK0.91465217
43NEK90.89983966
44MAPK120.87177892
45MAP3K30.86351890
46PTK20.83259573
47PRKAA20.82031491
48KSR20.81646266
49LRRK20.80879475
50BMX0.77429100
51AKT20.76858083
52PRKAA10.76143350
53TIE10.75745476
54TESK10.75436259
55MARK20.74952761
56PTK60.71405894
57MAPK70.67348655
58MAP3K110.66460125
59STK38L0.63963705
60PRKD10.63006419
61TBK10.62603896
62LIMK10.62241882
63DYRK1B0.61847953
64MTOR0.61044420
65VRK20.60885996
66CAMK2G0.60360007
67MAP3K100.59689768
68PRKD20.59094452
69MAPK40.58283360
70LATS10.57384803
71PAK40.57217376
72EPHA20.57117009
73ROCK10.55968580
74RPS6KB20.54686589
75MAP3K50.54307437
76EPHB10.53575936
77MAP3K10.52977832
78CAMK1G0.51764737
79DDR20.51261030
80BRAF0.49783347
81RPS6KC10.48481439
82RPS6KL10.48481439
83NME20.46867482
84MAP2K10.46126777
85RPS6KA60.44977809
86MAP2K60.42724943
87CDC42BPA0.42261452
88MAP2K40.41337910
89CAMK40.40948335
90MAP3K80.40605135
91DAPK30.40386663
92NTRK10.40059163
93RPS6KA20.37844406
94CDK90.37718343
95FGFR10.37637610
96TAOK20.37146175
97TAOK10.36959399
98STK40.36822168
99CDK40.36658863
100ZAP700.36246395
101PAK20.36044081
102CAMK2D0.35814910
103PIM20.31796866
104RPS6KA40.31620192
105TAF10.31208891
106EPHB20.31008833
107FER0.30628358
108RPS6KA10.30349617
109PAK30.29893843
110MAPKAPK20.29433754
111MAP2K20.27385489
112CDK80.26461786
113RET0.26140515
114MELK0.26137588
115CDK70.25649745
116CDK60.25493587
117STK30.25088321
118PTK2B0.24651729
119TGFBR20.24271020
120ABL20.24187942
121NEK20.23566898
122ERBB30.23176454
123PRKG20.22050116
124PDPK10.20306156
125MET0.20253640
126MARK30.20236217
127ROCK20.19345870
128MST1R0.18577702
129CDK120.18167592
130EPHA30.17943983
131PRKACB0.17873523
132MAP3K60.16381552
133MOS0.15924274
134STK380.15597961
135TTK0.15404762

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000206.04049108
22-Oxocarboxylic acid metabolism_Homo sapiens_hsa012104.44768085
3Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054103.50593224
4Dilated cardiomyopathy_Homo sapiens_hsa054143.25724864
5Cardiac muscle contraction_Homo sapiens_hsa042602.98416794
6Propanoate metabolism_Homo sapiens_hsa006402.82386014
7Carbon metabolism_Homo sapiens_hsa012002.73751324
8Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.60942513
9Fatty acid degradation_Homo sapiens_hsa000712.04151450
10Glycolysis / Gluconeogenesis_Homo sapiens_hsa000102.02144999
11Viral myocarditis_Homo sapiens_hsa054161.90615387
12Fatty acid metabolism_Homo sapiens_hsa012121.78481772
13Biosynthesis of amino acids_Homo sapiens_hsa012301.77766193
14Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.72980892
15Pyruvate metabolism_Homo sapiens_hsa006201.67379634
16Parkinsons disease_Homo sapiens_hsa050121.67325890
17Sulfur relay system_Homo sapiens_hsa041221.59774564
18Central carbon metabolism in cancer_Homo sapiens_hsa052301.57590178
19HIF-1 signaling pathway_Homo sapiens_hsa040661.53858723
20* Insulin signaling pathway_Homo sapiens_hsa049101.53797787
21* Insulin resistance_Homo sapiens_hsa049311.50383334
22Galactose metabolism_Homo sapiens_hsa000521.48760899
23Adipocytokine signaling pathway_Homo sapiens_hsa049201.43277030
24Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.41206939
25Focal adhesion_Homo sapiens_hsa045101.39429504
26Fatty acid biosynthesis_Homo sapiens_hsa000611.38139646
27* Glucagon signaling pathway_Homo sapiens_hsa049221.32886447
28* AMPK signaling pathway_Homo sapiens_hsa041521.29739762
29Oxidative phosphorylation_Homo sapiens_hsa001901.28740925
30Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.26769687
31Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.26194633
32Fructose and mannose metabolism_Homo sapiens_hsa000511.23210071
33Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.22717340
34Alzheimers disease_Homo sapiens_hsa050101.19606731
35Arginine biosynthesis_Homo sapiens_hsa002201.14606029
36Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.10514920
37Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.08999804
38PPAR signaling pathway_Homo sapiens_hsa033201.08062611
39Pentose phosphate pathway_Homo sapiens_hsa000301.07490731
40Other glycan degradation_Homo sapiens_hsa005111.05314814
41ECM-receptor interaction_Homo sapiens_hsa045121.00086069
42Adherens junction_Homo sapiens_hsa045200.98488885
43Tight junction_Homo sapiens_hsa045300.97614140
44Phenylalanine metabolism_Homo sapiens_hsa003600.97023467
45* Starch and sucrose metabolism_Homo sapiens_hsa005000.95118798
46Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.94458827
47Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.93704596
48Huntingtons disease_Homo sapiens_hsa050160.93250100
49Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.91321152
50Cyanoamino acid metabolism_Homo sapiens_hsa004600.89456764
51mTOR signaling pathway_Homo sapiens_hsa041500.89210993
52Longevity regulating pathway - mammal_Homo sapiens_hsa042110.88171218
53Proteoglycans in cancer_Homo sapiens_hsa052050.87175028
54Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.80528690
55Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.80480751
56cGMP-PKG signaling pathway_Homo sapiens_hsa040220.77540956
57Amoebiasis_Homo sapiens_hsa051460.76316904
58Prion diseases_Homo sapiens_hsa050200.75302544
59Leukocyte transendothelial migration_Homo sapiens_hsa046700.73676389
60Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.69882148
61Small cell lung cancer_Homo sapiens_hsa052220.67852728
62Lysine degradation_Homo sapiens_hsa003100.66878009
63AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.64599573
64Oxytocin signaling pathway_Homo sapiens_hsa049210.62391001
65Circadian rhythm_Homo sapiens_hsa047100.58420600
66Chronic myeloid leukemia_Homo sapiens_hsa052200.57785479
67VEGF signaling pathway_Homo sapiens_hsa043700.56203497
68Acute myeloid leukemia_Homo sapiens_hsa052210.56135844
69FoxO signaling pathway_Homo sapiens_hsa040680.55674869
70Thyroid hormone signaling pathway_Homo sapiens_hsa049190.54750687
71Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.53215818
72Legionellosis_Homo sapiens_hsa051340.52661797
73Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.51777880
74Melanogenesis_Homo sapiens_hsa049160.51606935
75ErbB signaling pathway_Homo sapiens_hsa040120.51527157
76Bladder cancer_Homo sapiens_hsa052190.51238855
77Regulation of actin cytoskeleton_Homo sapiens_hsa048100.49351658
78Thyroid cancer_Homo sapiens_hsa052160.48917509
79Toxoplasmosis_Homo sapiens_hsa051450.47014309
80Arginine and proline metabolism_Homo sapiens_hsa003300.46325983
81Platelet activation_Homo sapiens_hsa046110.45732505
82Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.45389884
83Renal cell carcinoma_Homo sapiens_hsa052110.43651294
84Glycosaminoglycan degradation_Homo sapiens_hsa005310.40361517
85MAPK signaling pathway_Homo sapiens_hsa040100.40290659
86MicroRNAs in cancer_Homo sapiens_hsa052060.40040622
87B cell receptor signaling pathway_Homo sapiens_hsa046620.39855095
88Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.39344729
89HTLV-I infection_Homo sapiens_hsa051660.38940773
90Phospholipase D signaling pathway_Homo sapiens_hsa040720.38359132
91beta-Alanine metabolism_Homo sapiens_hsa004100.37906548
92Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.37387291
93Inositol phosphate metabolism_Homo sapiens_hsa005620.37370683
94Type II diabetes mellitus_Homo sapiens_hsa049300.37029880
95Prostate cancer_Homo sapiens_hsa052150.36190949
96Vascular smooth muscle contraction_Homo sapiens_hsa042700.34925175
97Hippo signaling pathway_Homo sapiens_hsa043900.34787666
98Glycerolipid metabolism_Homo sapiens_hsa005610.33708520
99Neurotrophin signaling pathway_Homo sapiens_hsa047220.33072192
100Notch signaling pathway_Homo sapiens_hsa043300.32847173
101Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.32351686
102Fatty acid elongation_Homo sapiens_hsa000620.32054262
103Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.31807511
104Calcium signaling pathway_Homo sapiens_hsa040200.31053086
105Estrogen signaling pathway_Homo sapiens_hsa049150.30668001
106Melanoma_Homo sapiens_hsa052180.30546928
107Long-term potentiation_Homo sapiens_hsa047200.29656649
108Gastric acid secretion_Homo sapiens_hsa049710.28941085
109p53 signaling pathway_Homo sapiens_hsa041150.28844574
110Endometrial cancer_Homo sapiens_hsa052130.28815362
111Gap junction_Homo sapiens_hsa045400.28572332
112Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.27921953
113Leishmaniasis_Homo sapiens_hsa051400.27513780
114* PI3K-Akt signaling pathway_Homo sapiens_hsa041510.27309768
115Pathways in cancer_Homo sapiens_hsa052000.26841666
116Basal cell carcinoma_Homo sapiens_hsa052170.26511702
117Protein digestion and absorption_Homo sapiens_hsa049740.25135617
118Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.24400445
119Viral carcinogenesis_Homo sapiens_hsa052030.22723939
120Apoptosis_Homo sapiens_hsa042100.22446767
121Salmonella infection_Homo sapiens_hsa051320.18972419
122Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.18155037
123Cell cycle_Homo sapiens_hsa041100.16169867
124Non-small cell lung cancer_Homo sapiens_hsa052230.14924416
125Pancreatic cancer_Homo sapiens_hsa052120.14238881
126Fat digestion and absorption_Homo sapiens_hsa049750.13780789
127Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.13752012
128GnRH signaling pathway_Homo sapiens_hsa049120.13657347
129Glioma_Homo sapiens_hsa052140.12328164

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