Rank | Gene Set | Z-score |
---|---|---|
1 | muscle filament sliding (GO:0030049) | 9.45584803 |
2 | actin-myosin filament sliding (GO:0033275) | 9.45584803 |
3 | actin-mediated cell contraction (GO:0070252) | 7.76461593 |
4 | regulation of skeletal muscle contraction (GO:0014819) | 7.71488104 |
5 | sarcomere organization (GO:0045214) | 7.67871069 |
6 | plasma membrane repair (GO:0001778) | 7.17002295 |
7 | myofibril assembly (GO:0030239) | 6.47032335 |
8 | cardiac myofibril assembly (GO:0055003) | 6.14433815 |
9 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 6.12587395 |
10 | skeletal muscle contraction (GO:0003009) | 5.99419179 |
11 | tricarboxylic acid cycle (GO:0006099) | 5.89222796 |
12 | actin filament-based movement (GO:0030048) | 5.88207356 |
13 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 5.86310726 |
14 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 5.59204004 |
15 | carnitine shuttle (GO:0006853) | 5.53596917 |
16 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 5.50315425 |
17 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 5.32026769 |
18 | striated muscle contraction (GO:0006941) | 5.30489635 |
19 | actomyosin structure organization (GO:0031032) | 5.12008097 |
20 | skeletal muscle adaptation (GO:0043501) | 4.99137997 |
21 | cardiac muscle contraction (GO:0060048) | 4.94388185 |
22 | regulation of acyl-CoA biosynthetic process (GO:0050812) | 4.93705414 |
23 | cardiac muscle cell development (GO:0055013) | 4.85435577 |
24 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 4.84086437 |
25 | muscle cell fate commitment (GO:0042693) | 4.81527213 |
26 | regulation of cofactor metabolic process (GO:0051193) | 4.81028106 |
27 | regulation of coenzyme metabolic process (GO:0051196) | 4.81028106 |
28 | fatty acid transmembrane transport (GO:1902001) | 4.70132157 |
29 | cardiac cell development (GO:0055006) | 4.56144810 |
30 | regulation of sequestering of triglyceride (GO:0010889) | 4.31642747 |
31 | regulation of relaxation of muscle (GO:1901077) | 4.16077389 |
32 | NADH metabolic process (GO:0006734) | 4.15620615 |
33 | regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 4.14519302 |
34 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 4.10634836 |
35 | muscle contraction (GO:0006936) | 4.07220286 |
36 | carnitine transmembrane transport (GO:1902603) | 4.01595934 |
37 | cardiac muscle tissue morphogenesis (GO:0055008) | 4.00527831 |
38 | response to stimulus involved in regulation of muscle adaptation (GO:0014874) | 4.00309264 |
39 | heart process (GO:0003015) | 3.96697468 |
40 | heart contraction (GO:0060047) | 3.96697468 |
41 | cell-substrate adherens junction assembly (GO:0007045) | 3.94354026 |
42 | focal adhesion assembly (GO:0048041) | 3.94354026 |
43 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 3.87489340 |
44 | regulation of actin filament-based movement (GO:1903115) | 3.87357071 |
45 | regulation of cell communication by electrical coupling (GO:0010649) | 3.86249754 |
46 | skeletal muscle fiber development (GO:0048741) | 3.85715198 |
47 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.83953841 |
48 | gluconeogenesis (GO:0006094) | 3.76950191 |
49 | skeletal muscle tissue regeneration (GO:0043403) | 3.76710330 |
50 | muscle tissue morphogenesis (GO:0060415) | 3.75740720 |
51 | creatine metabolic process (GO:0006600) | 3.70752609 |
52 | muscle system process (GO:0003012) | 3.67372979 |
53 | cell-substrate junction assembly (GO:0007044) | 3.66112401 |
54 | striated muscle atrophy (GO:0014891) | 3.65848717 |
55 | heart trabecula formation (GO:0060347) | 3.65026340 |
56 | response to muscle activity (GO:0014850) | 3.63959285 |
57 | glycogen catabolic process (GO:0005980) | 3.62932339 |
58 | regulation of the force of heart contraction (GO:0002026) | 3.62570431 |
59 | amino-acid betaine transport (GO:0015838) | 3.62384335 |
60 | carnitine transport (GO:0015879) | 3.62384335 |
61 | striated muscle cell development (GO:0055002) | 3.60934668 |
62 | striated muscle adaptation (GO:0014888) | 3.59457881 |
63 | regulation of sulfur metabolic process (GO:0042762) | 3.58531131 |
64 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 3.58150889 |
65 | adherens junction assembly (GO:0034333) | 3.57889693 |
66 | adult heart development (GO:0007512) | 3.56860186 |
67 | cardiac muscle hypertrophy (GO:0003300) | 3.56548209 |
68 | protein hydroxylation (GO:0018126) | 3.55426214 |
69 | skeletal muscle tissue development (GO:0007519) | 3.54869986 |
70 | cytidine metabolic process (GO:0046087) | 3.50805299 |
71 | cytidine catabolic process (GO:0006216) | 3.50805299 |
72 | cytidine deamination (GO:0009972) | 3.50805299 |
73 | striated muscle hypertrophy (GO:0014897) | 3.49090612 |
74 | muscle fiber development (GO:0048747) | 3.47972748 |
75 | regulation of striated muscle contraction (GO:0006942) | 3.47908199 |
76 | positive regulation of myotube differentiation (GO:0010831) | 3.47844015 |
77 | hexose biosynthetic process (GO:0019319) | 3.43940172 |
78 | oxidative phosphorylation (GO:0006119) | 3.42310902 |
79 | negative regulation of cell size (GO:0045792) | 3.41095811 |
80 | ventricular cardiac muscle cell action potential (GO:0086005) | 3.36432349 |
81 | ventricular cardiac muscle tissue morphogenesis (GO:0055010) | 3.34069533 |
82 | glucan catabolic process (GO:0009251) | 3.33363648 |
83 | response to inactivity (GO:0014854) | 3.31895226 |
84 | negative regulation of necroptotic process (GO:0060546) | 3.29262952 |
85 | regulation of fatty acid oxidation (GO:0046320) | 3.25176877 |
86 | muscle organ morphogenesis (GO:0048644) | 3.24570321 |
87 | cellular polysaccharide catabolic process (GO:0044247) | 3.23409411 |
88 | IMP metabolic process (GO:0046040) | 3.23389864 |
89 | oxaloacetate metabolic process (GO:0006107) | 3.21739645 |
90 | myoblast fusion (GO:0007520) | 3.21121903 |
91 | regulation of sarcomere organization (GO:0060297) | 3.18540768 |
92 | monosaccharide biosynthetic process (GO:0046364) | 3.17446754 |
93 | lipid particle organization (GO:0034389) | 3.16047745 |
94 | muscle organ development (GO:0007517) | 3.15501564 |
95 | mitochondrial fusion (GO:0008053) | 3.14822317 |
96 | muscle cell development (GO:0055001) | 3.13626113 |
97 | 2-oxoglutarate metabolic process (GO:0006103) | 3.12615713 |
98 | myotube cell development (GO:0014904) | 3.12311703 |
99 | hemidesmosome assembly (GO:0031581) | 3.11101223 |
100 | fructose metabolic process (GO:0006000) | 3.10924383 |
101 | regulation of membrane repolarization (GO:0060306) | 3.10660765 |
102 | muscle structure development (GO:0061061) | 3.09874575 |
103 | muscle adaptation (GO:0043500) | 3.06852877 |
104 | muscle hypertrophy (GO:0014896) | 3.06485973 |
105 | syncytium formation by plasma membrane fusion (GO:0000768) | 3.06287910 |
106 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 3.05976067 |
107 | regulation of myotube differentiation (GO:0010830) | 3.05634850 |
108 | tricarboxylic acid metabolic process (GO:0072350) | 3.04545507 |
109 | 4-hydroxyproline metabolic process (GO:0019471) | 3.03618745 |
110 | polysaccharide catabolic process (GO:0000272) | 3.03307863 |
111 | peptidyl-proline hydroxylation (GO:0019511) | 3.00933678 |
112 | valine metabolic process (GO:0006573) | 3.00762297 |
113 | glycolytic process (GO:0006096) | 2.97090653 |
114 | muscle cell cellular homeostasis (GO:0046716) | 2.96641803 |
115 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 2.96544599 |
116 | muscle atrophy (GO:0014889) | 2.96010007 |
117 | negative regulation of muscle hypertrophy (GO:0014741) | 2.92969823 |
118 | positive regulation of calcium ion transmembrane transporter activity (GO:1901021) | 2.89602018 |
119 | * glycogen biosynthetic process (GO:0005978) | 2.89088919 |
120 | * glucan biosynthetic process (GO:0009250) | 2.89088919 |
121 | epithelial cell-cell adhesion (GO:0090136) | 2.88929090 |
122 | regulation of p38MAPK cascade (GO:1900744) | 2.88155101 |
123 | regulation of myoblast differentiation (GO:0045661) | 2.85625409 |
124 | regulation of skeletal muscle cell differentiation (GO:2001014) | 2.84959569 |
125 | basement membrane organization (GO:0071711) | 2.83045060 |
126 | Golgi transport vesicle coating (GO:0048200) | 2.76908709 |
127 | COPI coating of Golgi vesicle (GO:0048205) | 2.76908709 |
128 | barbed-end actin filament capping (GO:0051016) | 2.73993179 |
129 | * glycogen metabolic process (GO:0005977) | 2.72673755 |
130 | cardiac muscle adaptation (GO:0014887) | 2.70065687 |
131 | cardiac muscle hypertrophy in response to stress (GO:0014898) | 2.70065687 |
132 | muscle hypertrophy in response to stress (GO:0003299) | 2.70065687 |
133 | positive regulation of myoblast differentiation (GO:0045663) | 2.67913541 |
134 | apoptotic process involved in morphogenesis (GO:0060561) | 2.66168031 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 7.30693329 |
2 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 4.17751500 |
3 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.69600628 |
4 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 3.43784846 |
5 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.85763449 |
6 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.71635349 |
7 | CLOCK_20551151_ChIP-Seq_293T_Human | 2.70591877 |
8 | * TBX20_22328084_ChIP-Seq_HEART_Mouse | 2.60952855 |
9 | * TBX20_22080862_ChIP-Seq_HEART_Mouse | 2.60952855 |
10 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 2.54266884 |
11 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.49701206 |
12 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.37328673 |
13 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 2.36694910 |
14 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.33326490 |
15 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 2.18638915 |
16 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 2.06452131 |
17 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.99007611 |
18 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.94720851 |
19 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.93445169 |
20 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.91962495 |
21 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.89278325 |
22 | * NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 1.88661095 |
23 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.88542565 |
24 | * GATA4_21415370_ChIP-Seq_HL-1_Mouse | 1.88311545 |
25 | ATF3_27146783_Chip-Seq_COLON_Human | 1.77982880 |
26 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.75964616 |
27 | MYC_22102868_ChIP-Seq_BL_Human | 1.69336668 |
28 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.68345201 |
29 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.67567978 |
30 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.66570146 |
31 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.62342478 |
32 | KDM2B_26808549_Chip-Seq_K562_Human | 1.61098591 |
33 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.59946630 |
34 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.56892572 |
35 | * NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.56219249 |
36 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.55095847 |
37 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.52561883 |
38 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.52420294 |
39 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.51748445 |
40 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.50221771 |
41 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.49654963 |
42 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.49413479 |
43 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.48059784 |
44 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.47648155 |
45 | * SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.45755053 |
46 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.45413820 |
47 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.40162208 |
48 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.40112033 |
49 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.40075911 |
50 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.39955925 |
51 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.38586021 |
52 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.38378313 |
53 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.38233170 |
54 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.37771400 |
55 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.37695202 |
56 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.35880679 |
57 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.35737746 |
58 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.32265889 |
59 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.32229682 |
60 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.30828639 |
61 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.30742710 |
62 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.29700535 |
63 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.28685211 |
64 | SMC3_22415368_ChIP-Seq_MEFs_Mouse | 1.28631188 |
65 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.27532549 |
66 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.26342074 |
67 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.25915383 |
68 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.25644752 |
69 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.24735651 |
70 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.23903971 |
71 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.23530120 |
72 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.23391253 |
73 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.23378806 |
74 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.21507242 |
75 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.21423232 |
76 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 1.20784907 |
77 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.20640731 |
78 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 1.20311937 |
79 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.19575004 |
80 | STAT3_19079543_ChIP-ChIP_MESCs_Mouse | 1.18313878 |
81 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.16986034 |
82 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.16799697 |
83 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.14407167 |
84 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.13904386 |
85 | P68_20966046_ChIP-Seq_HELA_Human | 1.12923629 |
86 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.11694401 |
87 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.09949357 |
88 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.09725107 |
89 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 1.08609084 |
90 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.08394899 |
91 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.08203216 |
92 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.07553386 |
93 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 1.07427803 |
94 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.07398437 |
95 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.07319660 |
96 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.06509493 |
97 | MAF_26560356_Chip-Seq_TH1_Human | 1.05648795 |
98 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.03869951 |
99 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.02941407 |
100 | MAF_26560356_Chip-Seq_TH2_Human | 1.02264098 |
101 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.02248085 |
102 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.02166410 |
103 | SETDB1_19884255_ChIP-Seq_MESCs_Mouse | 1.02053364 |
104 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.00251423 |
105 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.00053352 |
106 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.99780680 |
107 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.99527281 |
108 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.99474502 |
109 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.99320287 |
110 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.99255955 |
111 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 0.98097629 |
112 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.97626284 |
113 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 0.97386389 |
114 | CTCF_21964334_ChIP-Seq_BJAB-B_Human | 0.96514919 |
115 | CTCF_21964334_Chip-Seq_Bcells_Human | 0.96353860 |
116 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.95766680 |
117 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 0.95073943 |
118 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.94706092 |
119 | * TP53_22127205_ChIP-Seq_IMR90_Human | 0.94652710 |
120 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.93450423 |
121 | TP63_22573176_ChIP-Seq_HFKS_Human | 0.93027839 |
122 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.92771649 |
123 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.91625011 |
124 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.91335531 |
125 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.90159885 |
126 | * SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.89147670 |
127 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.88837861 |
128 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.88688254 |
129 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 0.88583372 |
130 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 0.88333599 |
131 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.87028598 |
132 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.87015656 |
133 | SMC1_22415368_ChIP-Seq_MEFs_Mouse | 0.86955070 |
134 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 0.85221827 |
135 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.85212794 |
136 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.84042649 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003646_muscle_fatigue | 5.45324070 |
2 | MP0002837_dystrophic_cardiac_calcinosis | 4.93399332 |
3 | MP0000751_myopathy | 4.82104955 |
4 | MP0000749_muscle_degeneration | 4.47295605 |
5 | MP0004084_abnormal_cardiac_muscle | 4.08709188 |
6 | MP0004036_abnormal_muscle_relaxation | 3.66542406 |
7 | MP0004145_abnormal_muscle_electrophysio | 3.55326250 |
8 | MP0005451_abnormal_body_composition | 3.43937402 |
9 | MP0004087_abnormal_muscle_fiber | 3.23377173 |
10 | MP0000750_abnormal_muscle_regeneration | 3.17207728 |
11 | MP0004130_abnormal_muscle_cell | 3.00740166 |
12 | * MP0002106_abnormal_muscle_physiology | 2.96691439 |
13 | MP0005330_cardiomyopathy | 2.83393500 |
14 | MP0000759_abnormal_skeletal_muscle | 2.74871649 |
15 | MP0004215_abnormal_myocardial_fiber | 2.71863805 |
16 | MP0000747_muscle_weakness | 2.71013509 |
17 | MP0005620_abnormal_muscle_contractility | 2.66125692 |
18 | MP0002269_muscular_atrophy | 2.63843146 |
19 | * MP0005369_muscle_phenotype | 2.44035072 |
20 | MP0002972_abnormal_cardiac_muscle | 2.32858469 |
21 | MP0004233_abnormal_muscle_weight | 2.27876350 |
22 | MP0005666_abnormal_adipose_tissue | 2.19064881 |
23 | MP0005670_abnormal_white_adipose | 2.19034167 |
24 | MP0003705_abnormal_hypodermis_morpholog | 2.17388043 |
25 | MP0008438_abnormal_cutaneous_collagen | 2.17346252 |
26 | * MP0010630_abnormal_cardiac_muscle | 2.11468673 |
27 | MP0008775_abnormal_heart_ventricle | 2.07106897 |
28 | MP0004185_abnormal_adipocyte_glucose | 2.05869535 |
29 | * MP0001544_abnormal_cardiovascular_syste | 1.91819767 |
30 | * MP0005385_cardiovascular_system_phenoty | 1.91819767 |
31 | MP0003221_abnormal_cardiomyocyte_apopto | 1.91142791 |
32 | MP0000733_abnormal_muscle_development | 1.88021654 |
33 | MP0006138_congestive_heart_failure | 1.72667378 |
34 | MP0004484_altered_response_of | 1.69922271 |
35 | MP0003828_pulmonary_edema | 1.69426974 |
36 | MP0004858_abnormal_nervous_system | 1.66048435 |
37 | MP0003137_abnormal_impulse_conducting | 1.60881450 |
38 | MP0005375_adipose_tissue_phenotype | 1.60108900 |
39 | MP0003566_abnormal_cell_adhesion | 1.58255564 |
40 | MP0005275_abnormal_skin_tensile | 1.56467570 |
41 | MP0002332_abnormal_exercise_endurance | 1.50548593 |
42 | MP0006036_abnormal_mitochondrial_physio | 1.50451657 |
43 | MP0001661_extended_life_span | 1.45320380 |
44 | MP0003279_aneurysm | 1.36468667 |
45 | MP0002108_abnormal_muscle_morphology | 1.36120911 |
46 | MP0003950_abnormal_plasma_membrane | 1.34451706 |
47 | MP0002971_abnormal_brown_adipose | 1.26474067 |
48 | MP0000343_altered_response_to | 1.23177781 |
49 | MP0000013_abnormal_adipose_tissue | 1.08521110 |
50 | MP0000003_abnormal_adipose_tissue | 1.05679152 |
51 | * MP0000266_abnormal_heart_morphology | 1.03394736 |
52 | MP0004272_abnormal_basement_membrane | 1.03377813 |
53 | MP0002127_abnormal_cardiovascular_syste | 1.02281741 |
54 | MP0009780_abnormal_chondrocyte_physiolo | 1.01443634 |
55 | MP0000678_abnormal_parathyroid_gland | 1.00522329 |
56 | MP0005257_abnormal_intraocular_pressure | 1.00232305 |
57 | MP0008260_abnormal_autophagy | 0.98299117 |
58 | MP0005058_abnormal_lysosome_morphology | 0.96811848 |
59 | MP0002877_abnormal_melanocyte_morpholog | 0.95611897 |
60 | MP0005623_abnormal_meninges_morphology | 0.95174001 |
61 | MP0004510_myositis | 0.94031156 |
62 | MP0004085_abnormal_heartbeat | 0.90993343 |
63 | * MP0003567_abnormal_fetal_cardiomyocyte | 0.87695684 |
64 | MP0002234_abnormal_pharynx_morphology | 0.86411474 |
65 | MP0000579_abnormal_nail_morphology | 0.84896555 |
66 | MP0002249_abnormal_larynx_morphology | 0.82993390 |
67 | MP0010352_gastrointestinal_tract_polyps | 0.80919376 |
68 | MP0005266_abnormal_metabolism | 0.79953877 |
69 | MP0005503_abnormal_tendon_morphology | 0.78986170 |
70 | MP0009115_abnormal_fat_cell | 0.77599446 |
71 | MP0001299_abnormal_eye_distance/ | 0.76281635 |
72 | MP0009840_abnormal_foam_cell | 0.75712769 |
73 | MP0005076_abnormal_cell_differentiation | 0.73875080 |
74 | MP0005409_darkened_coat_color | 0.73247484 |
75 | MP0001348_abnormal_lacrimal_gland | 0.69790166 |
76 | MP0000467_abnormal_esophagus_morphology | 0.68655183 |
77 | MP0003453_abnormal_keratinocyte_physiol | 0.68313403 |
78 | MP0003941_abnormal_skin_development | 0.67683719 |
79 | * MP0002128_abnormal_blood_circulation | 0.67533028 |
80 | MP0006035_abnormal_mitochondrial_morpho | 0.65586520 |
81 | MP0003191_abnormal_cellular_cholesterol | 0.64081011 |
82 | MP0003045_fibrosis | 0.63470838 |
83 | MP0005334_abnormal_fat_pad | 0.61965187 |
84 | MP0002796_impaired_skin_barrier | 0.61894506 |
85 | MP0002970_abnormal_white_adipose | 0.61596032 |
86 | MP0003984_embryonic_growth_retardation | 0.61278589 |
87 | MP0001958_emphysema | 0.60283777 |
88 | MP0002088_abnormal_embryonic_growth/wei | 0.59912814 |
89 | MP0002925_abnormal_cardiovascular_devel | 0.59717180 |
90 | MP0010030_abnormal_orbit_morphology | 0.58643788 |
91 | MP0005023_abnormal_wound_healing | 0.58172706 |
92 | MP0004197_abnormal_fetal_growth/weight/ | 0.58065087 |
93 | MP0000372_irregular_coat_pigmentation | 0.57815896 |
94 | MP0008961_abnormal_basal_metabolism | 0.56454489 |
95 | MP0005165_increased_susceptibility_to | 0.54426862 |
96 | MP0000767_abnormal_smooth_muscle | 0.54284678 |
97 | MP0006054_spinal_hemorrhage | 0.50635237 |
98 | * MP0001614_abnormal_blood_vessel | 0.49875011 |
99 | MP0010234_abnormal_vibrissa_follicle | 0.49135209 |
100 | MP0010368_abnormal_lymphatic_system | 0.48800128 |
101 | MP0002114_abnormal_axial_skeleton | 0.48365189 |
102 | MP0001849_ear_inflammation | 0.47100088 |
103 | MP0000534_abnormal_ureter_morphology | 0.46166022 |
104 | MP0005380_embryogenesis_phenotype | 0.45750451 |
105 | MP0001672_abnormal_embryogenesis/_devel | 0.45750451 |
106 | MP0005501_abnormal_skin_physiology | 0.44910014 |
107 | MP0009384_cardiac_valve_regurgitation | 0.44709768 |
108 | MP0003948_abnormal_gas_homeostasis | 0.44514341 |
109 | MP0002060_abnormal_skin_morphology | 0.43751446 |
110 | MP0009278_abnormal_bone_marrow | 0.42969944 |
111 | MP0003385_abnormal_body_wall | 0.42041393 |
112 | MP0009672_abnormal_birth_weight | 0.40511211 |
113 | MP0001730_embryonic_growth_arrest | 0.40341616 |
114 | MP0001853_heart_inflammation | 0.39675214 |
115 | MP0003959_abnormal_lean_body | 0.39091391 |
116 | MP0005452_abnormal_adipose_tissue | 0.38338142 |
117 | MP0001879_abnormal_lymphatic_vessel | 0.37856016 |
118 | * MP0002078_abnormal_glucose_homeostasis | 0.37443970 |
119 | MP0002896_abnormal_bone_mineralization | 0.37199005 |
120 | MP0000762_abnormal_tongue_morphology | 0.37189236 |
121 | MP0001784_abnormal_fluid_regulation | 0.36694742 |
122 | MP0003091_abnormal_cell_migration | 0.36280004 |
123 | MP0000428_abnormal_craniofacial_morphol | 0.35961806 |
124 | MP0009250_abnormal_appendicular_skeleto | 0.35791575 |
125 | MP0001697_abnormal_embryo_size | 0.34763235 |
126 | MP0000230_abnormal_systemic_arterial | 0.34310779 |
127 | MP0008770_decreased_survivor_rate | 0.33579959 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Muscle fiber inclusion bodies (HP:0100299) | 7.15287733 |
2 | Exercise-induced muscle cramps (HP:0003710) | 7.13111638 |
3 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 6.90075148 |
4 | Exercise-induced myalgia (HP:0003738) | 6.80695512 |
5 | Type 1 muscle fiber predominance (HP:0003803) | 6.70476750 |
6 | Nemaline bodies (HP:0003798) | 6.30249495 |
7 | Calf muscle hypertrophy (HP:0008981) | 5.57750419 |
8 | Muscle hypertrophy of the lower extremities (HP:0008968) | 5.56853092 |
9 | Muscle fiber splitting (HP:0003555) | 5.55188490 |
10 | Myoglobinuria (HP:0002913) | 5.31479753 |
11 | Increased connective tissue (HP:0009025) | 5.02257827 |
12 | Hyporeflexia of lower limbs (HP:0002600) | 4.96423143 |
13 | Distal arthrogryposis (HP:0005684) | 4.93402301 |
14 | Difficulty running (HP:0009046) | 4.91257998 |
15 | Sudden death (HP:0001699) | 4.91237274 |
16 | Rhabdomyolysis (HP:0003201) | 4.54074708 |
17 | Abnormality of the calf musculature (HP:0001430) | 4.50112099 |
18 | EMG: myopathic abnormalities (HP:0003458) | 4.44679694 |
19 | Abnormality of the left ventricular outflow tract (HP:0011103) | 4.41892601 |
20 | Subaortic stenosis (HP:0001682) | 4.41892601 |
21 | Ulnar deviation of the wrist (HP:0003049) | 4.28645084 |
22 | Myopathic facies (HP:0002058) | 4.26706805 |
23 | Round ear (HP:0100830) | 4.17908669 |
24 | Ventricular tachycardia (HP:0004756) | 4.10012506 |
25 | Abnormality of skeletal muscle fiber size (HP:0012084) | 3.88441030 |
26 | Increased variability in muscle fiber diameter (HP:0003557) | 3.63240396 |
27 | Muscle stiffness (HP:0003552) | 3.61943191 |
28 | Asymmetric septal hypertrophy (HP:0001670) | 3.61403042 |
29 | Myotonia (HP:0002486) | 3.58735834 |
30 | Calcaneovalgus deformity (HP:0001848) | 3.57338716 |
31 | Lipoatrophy (HP:0100578) | 3.54778054 |
32 | Difficulty climbing stairs (HP:0003551) | 3.54007994 |
33 | Neck muscle weakness (HP:0000467) | 3.32922837 |
34 | Deformed tarsal bones (HP:0008119) | 3.27311804 |
35 | Right ventricular cardiomyopathy (HP:0011663) | 3.21507795 |
36 | Atrial fibrillation (HP:0005110) | 2.95741757 |
37 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.92371373 |
38 | Dilated cardiomyopathy (HP:0001644) | 2.90623317 |
39 | Absent phalangeal crease (HP:0006109) | 2.82549870 |
40 | Distal lower limb muscle weakness (HP:0009053) | 2.77523779 |
41 | Primary atrial arrhythmia (HP:0001692) | 2.75235921 |
42 | Areflexia of lower limbs (HP:0002522) | 2.75165137 |
43 | Spinal rigidity (HP:0003306) | 2.70880541 |
44 | Frequent falls (HP:0002359) | 2.69625435 |
45 | Rimmed vacuoles (HP:0003805) | 2.68347076 |
46 | Supraventricular tachycardia (HP:0004755) | 2.66661647 |
47 | Scapular winging (HP:0003691) | 2.65905675 |
48 | Supraventricular arrhythmia (HP:0005115) | 2.65060530 |
49 | Slender build (HP:0001533) | 2.56849956 |
50 | Palpitations (HP:0001962) | 2.56458704 |
51 | Abnormality of the calcaneus (HP:0008364) | 2.51685007 |
52 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.51535710 |
53 | Generalized muscle weakness (HP:0003324) | 2.50330263 |
54 | Malignant hyperthermia (HP:0002047) | 2.49657926 |
55 | EMG: neuropathic changes (HP:0003445) | 2.40901497 |
56 | Ventricular arrhythmia (HP:0004308) | 2.37793803 |
57 | Bundle branch block (HP:0011710) | 2.37182759 |
58 | Popliteal pterygium (HP:0009756) | 2.37036343 |
59 | Limb-girdle muscle atrophy (HP:0003797) | 2.32792574 |
60 | Achilles tendon contracture (HP:0001771) | 2.31342626 |
61 | Facial diplegia (HP:0001349) | 2.30052059 |
62 | Abnormal finger flexion creases (HP:0006143) | 2.24962098 |
63 | Distal lower limb amyotrophy (HP:0008944) | 2.24552942 |
64 | Hypoplastic ischia (HP:0003175) | 2.23460851 |
65 | Limb-girdle muscle weakness (HP:0003325) | 2.22265785 |
66 | Fetal akinesia sequence (HP:0001989) | 2.21534971 |
67 | Gowers sign (HP:0003391) | 2.20551611 |
68 | Ragged-red muscle fibers (HP:0003200) | 2.19436489 |
69 | Muscular dystrophy (HP:0003560) | 2.18852859 |
70 | Proximal amyotrophy (HP:0007126) | 2.12913646 |
71 | Pelvic girdle muscle weakness (HP:0003749) | 2.12464790 |
72 | Prolonged QT interval (HP:0001657) | 2.10404187 |
73 | Hip contracture (HP:0003273) | 2.05706255 |
74 | Ankle contracture (HP:0006466) | 2.04690359 |
75 | Abnormality of the musculature of the pelvis (HP:0001469) | 2.03660877 |
76 | Abnormality of the hip-girdle musculature (HP:0001445) | 2.03660877 |
77 | Abnormality of the shoulder girdle musculature (HP:0001435) | 2.02616298 |
78 | Easy fatigability (HP:0003388) | 2.00129422 |
79 | Abnormality of the Achilles tendon (HP:0005109) | 1.99365842 |
80 | Protrusio acetabuli (HP:0003179) | 1.97941891 |
81 | Generalized amyotrophy (HP:0003700) | 1.97842455 |
82 | Progressive muscle weakness (HP:0003323) | 1.97828170 |
83 | Heart block (HP:0012722) | 1.97763515 |
84 | Abnormality of the neuromuscular junction (HP:0003398) | 1.96658172 |
85 | Fatigable weakness (HP:0003473) | 1.96658172 |
86 | Syncope (HP:0001279) | 1.95199519 |
87 | Shoulder girdle muscle weakness (HP:0003547) | 1.95193842 |
88 | Abnormal atrioventricular conduction (HP:0005150) | 1.94006588 |
89 | Atrioventricular block (HP:0001678) | 1.90779813 |
90 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 1.89130190 |
91 | Waddling gait (HP:0002515) | 1.88987852 |
92 | Weak cry (HP:0001612) | 1.88534302 |
93 | Abnormality of the ischium (HP:0003174) | 1.87369817 |
94 | Fragile skin (HP:0001030) | 1.85394049 |
95 | Conjunctival hamartoma (HP:0100780) | 1.83577805 |
96 | Bulbar palsy (HP:0001283) | 1.82420754 |
97 | Pterygium (HP:0001059) | 1.80788635 |
98 | Thin ribs (HP:0000883) | 1.78091443 |
99 | Broad metatarsal (HP:0001783) | 1.75422150 |
100 | Respiratory insufficiency due to muscle weakness (HP:0002747) | 1.73827637 |
101 | Increased muscle lipid content (HP:0009058) | 1.71827580 |
102 | Abnormality of placental membranes (HP:0011409) | 1.69924537 |
103 | Amniotic constriction ring (HP:0009775) | 1.69924537 |
104 | Cerebral aneurysm (HP:0004944) | 1.67624903 |
105 | Metatarsus adductus (HP:0001840) | 1.67255374 |
106 | Premature rupture of membranes (HP:0001788) | 1.64763284 |
107 | Wrist flexion contracture (HP:0001239) | 1.64580340 |
108 | Abnormality of the foot musculature (HP:0001436) | 1.64321502 |
109 | Stridor (HP:0010307) | 1.62866329 |
110 | Atrophic scars (HP:0001075) | 1.61515326 |
111 | Congenital hip dislocation (HP:0001374) | 1.61145141 |
112 | Aplasia of the musculature (HP:0100854) | 1.59830043 |
113 | Muscle fiber atrophy (HP:0100295) | 1.56734910 |
114 | Trismus (HP:0000211) | 1.56690746 |
115 | Hepatic necrosis (HP:0002605) | 1.56356935 |
116 | Foot dorsiflexor weakness (HP:0009027) | 1.55904241 |
117 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.55896983 |
118 | Abnormality of alanine metabolism (HP:0010916) | 1.55896983 |
119 | Hyperalaninemia (HP:0003348) | 1.55896983 |
120 | Abnormality of the tricuspid valve (HP:0001702) | 1.55873369 |
121 | Lower limb amyotrophy (HP:0007210) | 1.55697898 |
122 | Palmoplantar keratoderma (HP:0000982) | 1.54667358 |
123 | Breech presentation (HP:0001623) | 1.53473797 |
124 | Hypoplastic heart (HP:0001961) | 1.51549170 |
125 | Reduced subcutaneous adipose tissue (HP:0003758) | 1.48746186 |
126 | Back pain (HP:0003418) | 1.47293659 |
Rank | Gene Set | Z-score |
---|---|---|
1 | OBSCN | 6.08161462 |
2 | TTN | 6.04581710 |
3 | TRIB3 | 4.32787484 |
4 | PKN2 | 3.79240882 |
5 | PHKG1 | 3.59998361 |
6 | PHKG2 | 3.59998361 |
7 | NEK1 | 3.00281279 |
8 | SMG1 | 2.88656082 |
9 | PDK3 | 2.76789923 |
10 | PDK4 | 2.76789923 |
11 | ICK | 2.17929449 |
12 | DMPK | 2.17083702 |
13 | BCKDK | 2.12455866 |
14 | MAP2K3 | 2.07410240 |
15 | PIK3CG | 2.00407909 |
16 | PRPF4B | 1.93939016 |
17 | LMTK2 | 1.72127247 |
18 | MYLK | 1.64760054 |
19 | IRAK3 | 1.61889134 |
20 | PDK2 | 1.56843625 |
21 | FLT3 | 1.56741296 |
22 | MAPKAPK3 | 1.54511595 |
23 | EEF2K | 1.54129330 |
24 | NME1 | 1.51943807 |
25 | PIK3CA | 1.51776578 |
26 | RIPK1 | 1.39870506 |
27 | STK24 | 1.32105194 |
28 | ILK | 1.23855784 |
29 | ERN1 | 1.20117933 |
30 | SIK1 | 1.19191694 |
31 | MAP3K13 | 1.18134556 |
32 | TRPM7 | 1.16217875 |
33 | ARAF | 1.14849010 |
34 | MAP3K7 | 1.09052199 |
35 | LATS2 | 1.05644600 |
36 | PDGFRA | 1.03527509 |
37 | MUSK | 1.02894805 |
38 | CAMK1D | 1.01313650 |
39 | FGFR4 | 0.99944518 |
40 | PINK1 | 0.99463542 |
41 | PRKD3 | 0.97849724 |
42 | ZAK | 0.91465217 |
43 | NEK9 | 0.89983966 |
44 | MAPK12 | 0.87177892 |
45 | MAP3K3 | 0.86351890 |
46 | PTK2 | 0.83259573 |
47 | PRKAA2 | 0.82031491 |
48 | KSR2 | 0.81646266 |
49 | LRRK2 | 0.80879475 |
50 | BMX | 0.77429100 |
51 | AKT2 | 0.76858083 |
52 | PRKAA1 | 0.76143350 |
53 | TIE1 | 0.75745476 |
54 | TESK1 | 0.75436259 |
55 | MARK2 | 0.74952761 |
56 | PTK6 | 0.71405894 |
57 | MAPK7 | 0.67348655 |
58 | MAP3K11 | 0.66460125 |
59 | STK38L | 0.63963705 |
60 | PRKD1 | 0.63006419 |
61 | TBK1 | 0.62603896 |
62 | LIMK1 | 0.62241882 |
63 | DYRK1B | 0.61847953 |
64 | MTOR | 0.61044420 |
65 | VRK2 | 0.60885996 |
66 | CAMK2G | 0.60360007 |
67 | MAP3K10 | 0.59689768 |
68 | PRKD2 | 0.59094452 |
69 | MAPK4 | 0.58283360 |
70 | LATS1 | 0.57384803 |
71 | PAK4 | 0.57217376 |
72 | EPHA2 | 0.57117009 |
73 | ROCK1 | 0.55968580 |
74 | RPS6KB2 | 0.54686589 |
75 | MAP3K5 | 0.54307437 |
76 | EPHB1 | 0.53575936 |
77 | MAP3K1 | 0.52977832 |
78 | CAMK1G | 0.51764737 |
79 | DDR2 | 0.51261030 |
80 | BRAF | 0.49783347 |
81 | RPS6KC1 | 0.48481439 |
82 | RPS6KL1 | 0.48481439 |
83 | NME2 | 0.46867482 |
84 | MAP2K1 | 0.46126777 |
85 | RPS6KA6 | 0.44977809 |
86 | MAP2K6 | 0.42724943 |
87 | CDC42BPA | 0.42261452 |
88 | MAP2K4 | 0.41337910 |
89 | CAMK4 | 0.40948335 |
90 | MAP3K8 | 0.40605135 |
91 | DAPK3 | 0.40386663 |
92 | NTRK1 | 0.40059163 |
93 | RPS6KA2 | 0.37844406 |
94 | CDK9 | 0.37718343 |
95 | FGFR1 | 0.37637610 |
96 | TAOK2 | 0.37146175 |
97 | TAOK1 | 0.36959399 |
98 | STK4 | 0.36822168 |
99 | CDK4 | 0.36658863 |
100 | ZAP70 | 0.36246395 |
101 | PAK2 | 0.36044081 |
102 | CAMK2D | 0.35814910 |
103 | PIM2 | 0.31796866 |
104 | RPS6KA4 | 0.31620192 |
105 | TAF1 | 0.31208891 |
106 | EPHB2 | 0.31008833 |
107 | FER | 0.30628358 |
108 | RPS6KA1 | 0.30349617 |
109 | PAK3 | 0.29893843 |
110 | MAPKAPK2 | 0.29433754 |
111 | MAP2K2 | 0.27385489 |
112 | CDK8 | 0.26461786 |
113 | RET | 0.26140515 |
114 | MELK | 0.26137588 |
115 | CDK7 | 0.25649745 |
116 | CDK6 | 0.25493587 |
117 | STK3 | 0.25088321 |
118 | PTK2B | 0.24651729 |
119 | TGFBR2 | 0.24271020 |
120 | ABL2 | 0.24187942 |
121 | NEK2 | 0.23566898 |
122 | ERBB3 | 0.23176454 |
123 | PRKG2 | 0.22050116 |
124 | PDPK1 | 0.20306156 |
125 | MET | 0.20253640 |
126 | MARK3 | 0.20236217 |
127 | ROCK2 | 0.19345870 |
128 | MST1R | 0.18577702 |
129 | CDK12 | 0.18167592 |
130 | EPHA3 | 0.17943983 |
131 | PRKACB | 0.17873523 |
132 | MAP3K6 | 0.16381552 |
133 | MOS | 0.15924274 |
134 | STK38 | 0.15597961 |
135 | TTK | 0.15404762 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 6.04049108 |
2 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 4.44768085 |
3 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 3.50593224 |
4 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 3.25724864 |
5 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.98416794 |
6 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.82386014 |
7 | Carbon metabolism_Homo sapiens_hsa01200 | 2.73751324 |
8 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 2.60942513 |
9 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.04151450 |
10 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 2.02144999 |
11 | Viral myocarditis_Homo sapiens_hsa05416 | 1.90615387 |
12 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.78481772 |
13 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.77766193 |
14 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.72980892 |
15 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.67379634 |
16 | Parkinsons disease_Homo sapiens_hsa05012 | 1.67325890 |
17 | Sulfur relay system_Homo sapiens_hsa04122 | 1.59774564 |
18 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.57590178 |
19 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 1.53858723 |
20 | * Insulin signaling pathway_Homo sapiens_hsa04910 | 1.53797787 |
21 | * Insulin resistance_Homo sapiens_hsa04931 | 1.50383334 |
22 | Galactose metabolism_Homo sapiens_hsa00052 | 1.48760899 |
23 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 1.43277030 |
24 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.41206939 |
25 | Focal adhesion_Homo sapiens_hsa04510 | 1.39429504 |
26 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.38139646 |
27 | * Glucagon signaling pathway_Homo sapiens_hsa04922 | 1.32886447 |
28 | * AMPK signaling pathway_Homo sapiens_hsa04152 | 1.29739762 |
29 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.28740925 |
30 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.26769687 |
31 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.26194633 |
32 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.23210071 |
33 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.22717340 |
34 | Alzheimers disease_Homo sapiens_hsa05010 | 1.19606731 |
35 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.14606029 |
36 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.10514920 |
37 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.08999804 |
38 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.08062611 |
39 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.07490731 |
40 | Other glycan degradation_Homo sapiens_hsa00511 | 1.05314814 |
41 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.00086069 |
42 | Adherens junction_Homo sapiens_hsa04520 | 0.98488885 |
43 | Tight junction_Homo sapiens_hsa04530 | 0.97614140 |
44 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.97023467 |
45 | * Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.95118798 |
46 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.94458827 |
47 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.93704596 |
48 | Huntingtons disease_Homo sapiens_hsa05016 | 0.93250100 |
49 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.91321152 |
50 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.89456764 |
51 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.89210993 |
52 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.88171218 |
53 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.87175028 |
54 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.80528690 |
55 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.80480751 |
56 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.77540956 |
57 | Amoebiasis_Homo sapiens_hsa05146 | 0.76316904 |
58 | Prion diseases_Homo sapiens_hsa05020 | 0.75302544 |
59 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.73676389 |
60 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.69882148 |
61 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.67852728 |
62 | Lysine degradation_Homo sapiens_hsa00310 | 0.66878009 |
63 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.64599573 |
64 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.62391001 |
65 | Circadian rhythm_Homo sapiens_hsa04710 | 0.58420600 |
66 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.57785479 |
67 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.56203497 |
68 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.56135844 |
69 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.55674869 |
70 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.54750687 |
71 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.53215818 |
72 | Legionellosis_Homo sapiens_hsa05134 | 0.52661797 |
73 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.51777880 |
74 | Melanogenesis_Homo sapiens_hsa04916 | 0.51606935 |
75 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.51527157 |
76 | Bladder cancer_Homo sapiens_hsa05219 | 0.51238855 |
77 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.49351658 |
78 | Thyroid cancer_Homo sapiens_hsa05216 | 0.48917509 |
79 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.47014309 |
80 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.46325983 |
81 | Platelet activation_Homo sapiens_hsa04611 | 0.45732505 |
82 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.45389884 |
83 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.43651294 |
84 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.40361517 |
85 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.40290659 |
86 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.40040622 |
87 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.39855095 |
88 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.39344729 |
89 | HTLV-I infection_Homo sapiens_hsa05166 | 0.38940773 |
90 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.38359132 |
91 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.37906548 |
92 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.37387291 |
93 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.37370683 |
94 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.37029880 |
95 | Prostate cancer_Homo sapiens_hsa05215 | 0.36190949 |
96 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.34925175 |
97 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.34787666 |
98 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.33708520 |
99 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.33072192 |
100 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.32847173 |
101 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.32351686 |
102 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.32054262 |
103 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.31807511 |
104 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.31053086 |
105 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.30668001 |
106 | Melanoma_Homo sapiens_hsa05218 | 0.30546928 |
107 | Long-term potentiation_Homo sapiens_hsa04720 | 0.29656649 |
108 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.28941085 |
109 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.28844574 |
110 | Endometrial cancer_Homo sapiens_hsa05213 | 0.28815362 |
111 | Gap junction_Homo sapiens_hsa04540 | 0.28572332 |
112 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.27921953 |
113 | Leishmaniasis_Homo sapiens_hsa05140 | 0.27513780 |
114 | * PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.27309768 |
115 | Pathways in cancer_Homo sapiens_hsa05200 | 0.26841666 |
116 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.26511702 |
117 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.25135617 |
118 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.24400445 |
119 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.22723939 |
120 | Apoptosis_Homo sapiens_hsa04210 | 0.22446767 |
121 | Salmonella infection_Homo sapiens_hsa05132 | 0.18972419 |
122 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.18155037 |
123 | Cell cycle_Homo sapiens_hsa04110 | 0.16169867 |
124 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.14924416 |
125 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.14238881 |
126 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.13780789 |
127 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.13752012 |
128 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.13657347 |
129 | Glioma_Homo sapiens_hsa05214 | 0.12328164 |