

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 6.35628760 |
| 2 | proteasome assembly (GO:0043248) | 6.19928188 |
| 3 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 5.16152796 |
| 4 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 5.16152796 |
| 5 | isotype switching (GO:0045190) | 5.16152796 |
| 6 | regulation of mitotic spindle checkpoint (GO:1903504) | 4.42312386 |
| 7 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 4.42312386 |
| 8 | rRNA modification (GO:0000154) | 4.30236477 |
| 9 | ATP synthesis coupled proton transport (GO:0015986) | 4.16024593 |
| 10 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.16024593 |
| 11 | protein neddylation (GO:0045116) | 4.08031443 |
| 12 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.02124982 |
| 13 | cytidine metabolic process (GO:0046087) | 3.95635911 |
| 14 | cytidine catabolic process (GO:0006216) | 3.95635911 |
| 15 | cytidine deamination (GO:0009972) | 3.95635911 |
| 16 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.86625512 |
| 17 | rRNA methylation (GO:0031167) | 3.81355218 |
| 18 | maturation of 5.8S rRNA (GO:0000460) | 3.78731286 |
| 19 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.78498529 |
| 20 | piRNA metabolic process (GO:0034587) | 3.67794260 |
| 21 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.62508144 |
| 22 | protein complex biogenesis (GO:0070271) | 3.62287733 |
| 23 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.59403790 |
| 24 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.55726213 |
| 25 | somatic recombination of immunoglobulin gene segments (GO:0016447) | 3.50408591 |
| 26 | protein-cofactor linkage (GO:0018065) | 3.48252605 |
| 27 | pseudouridine synthesis (GO:0001522) | 3.46391405 |
| 28 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.45496611 |
| 29 | electron transport chain (GO:0022900) | 3.44356302 |
| 30 | respiratory electron transport chain (GO:0022904) | 3.43282597 |
| 31 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.42761176 |
| 32 | somatic diversification of immunoglobulins (GO:0016445) | 3.41967096 |
| 33 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.41460608 |
| 34 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.41460608 |
| 35 | chaperone-mediated protein transport (GO:0072321) | 3.39125708 |
| 36 | NADH dehydrogenase complex assembly (GO:0010257) | 3.38250385 |
| 37 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.38250385 |
| 38 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.38250385 |
| 39 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.36796054 |
| 40 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.35126177 |
| 41 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.31848826 |
| 42 | rRNA catabolic process (GO:0016075) | 3.31179723 |
| 43 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.30599874 |
| 44 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.30599874 |
| 45 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.30599874 |
| 46 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.25994283 |
| 47 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.25994283 |
| 48 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.25684806 |
| 49 | positive regulation of T cell migration (GO:2000406) | 3.24360756 |
| 50 | interferon-gamma production (GO:0032609) | 3.23137495 |
| 51 | respiratory chain complex IV assembly (GO:0008535) | 3.18236752 |
| 52 | S-adenosylmethionine metabolic process (GO:0046500) | 3.16580044 |
| 53 | synapsis (GO:0007129) | 3.16203394 |
| 54 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.14834300 |
| 55 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.13984678 |
| 56 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.13984678 |
| 57 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.13523503 |
| 58 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.12465213 |
| 59 | cytochrome complex assembly (GO:0017004) | 3.07139726 |
| 60 | protein deneddylation (GO:0000338) | 3.07120910 |
| 61 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.04547063 |
| 62 | cullin deneddylation (GO:0010388) | 3.04388671 |
| 63 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.03175715 |
| 64 | negative regulation of ligase activity (GO:0051352) | 3.03175715 |
| 65 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.99141780 |
| 66 | regulation of immunoglobulin secretion (GO:0051023) | 2.95025389 |
| 67 | termination of RNA polymerase III transcription (GO:0006386) | 2.93257530 |
| 68 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.93257530 |
| 69 | positive regulation of prostaglandin secretion (GO:0032308) | 2.90583989 |
| 70 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.86744177 |
| 71 | chromatin remodeling at centromere (GO:0031055) | 2.86630786 |
| 72 | GTP biosynthetic process (GO:0006183) | 2.85360499 |
| 73 | regulation of mitochondrial translation (GO:0070129) | 2.82598216 |
| 74 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.79675517 |
| 75 | rRNA processing (GO:0006364) | 2.78172210 |
| 76 | behavioral response to nicotine (GO:0035095) | 2.77717744 |
| 77 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.76726000 |
| 78 | protein targeting to mitochondrion (GO:0006626) | 2.76369905 |
| 79 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.75988485 |
| 80 | rRNA metabolic process (GO:0016072) | 2.75838730 |
| 81 | somatic diversification of immune receptors (GO:0002200) | 2.75098465 |
| 82 | somatic cell DNA recombination (GO:0016444) | 2.74902965 |
| 83 | somatic diversification of immune receptors via germline recombination within a single locus (GO:000 | 2.74902965 |
| 84 | L-methionine salvage (GO:0071267) | 2.71550440 |
| 85 | L-methionine biosynthetic process (GO:0071265) | 2.71550440 |
| 86 | amino acid salvage (GO:0043102) | 2.71550440 |
| 87 | regulation of T cell migration (GO:2000404) | 2.70858099 |
| 88 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.69099185 |
| 89 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.69099185 |
| 90 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.68585604 |
| 91 | ribosomal small subunit assembly (GO:0000028) | 2.68469120 |
| 92 | positive regulation of lymphocyte migration (GO:2000403) | 2.67637172 |
| 93 | ribosome biogenesis (GO:0042254) | 2.66291297 |
| 94 | cellular ketone body metabolic process (GO:0046950) | 2.65163176 |
| 95 | inner mitochondrial membrane organization (GO:0007007) | 2.64502472 |
| 96 | positive regulation of ligase activity (GO:0051351) | 2.62329178 |
| 97 | ubiquinone biosynthetic process (GO:0006744) | 2.59909991 |
| 98 | CENP-A containing nucleosome assembly (GO:0034080) | 2.59843633 |
| 99 | establishment of protein localization to mitochondrion (GO:0072655) | 2.59692208 |
| 100 | B cell activation involved in immune response (GO:0002312) | 2.59364691 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.48455094 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.30703777 |
| 3 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.56608407 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.43198807 |
| 5 | VDR_22108803_ChIP-Seq_LS180_Human | 3.20500418 |
| 6 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.04423440 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.86809073 |
| 8 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.82178577 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.70497026 |
| 10 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.57731293 |
| 11 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.49238289 |
| 12 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.37920225 |
| 13 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.37522734 |
| 14 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.37059720 |
| 15 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.29932839 |
| 16 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.24606264 |
| 17 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.17245379 |
| 18 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.07252734 |
| 19 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.98022402 |
| 20 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.95393716 |
| 21 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.91900731 |
| 22 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.89363207 |
| 23 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.86727785 |
| 24 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.85847309 |
| 25 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.83866167 |
| 26 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.83812369 |
| 27 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.80026285 |
| 28 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.79928580 |
| 29 | EWS_26573619_Chip-Seq_HEK293_Human | 1.74781152 |
| 30 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.72661968 |
| 31 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.72075549 |
| 32 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.67357101 |
| 33 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.65122683 |
| 34 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.54410563 |
| 35 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.49800054 |
| 36 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.46798140 |
| 37 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.44697122 |
| 38 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.43934356 |
| 39 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.36095208 |
| 40 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.34629639 |
| 41 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.32670197 |
| 42 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.32670197 |
| 43 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.31088249 |
| 44 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.29681440 |
| 45 | GATA3_26560356_Chip-Seq_TH2_Human | 1.29503094 |
| 46 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.29382155 |
| 47 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.27158018 |
| 48 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.26012903 |
| 49 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.26003355 |
| 50 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.25041735 |
| 51 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.24938097 |
| 52 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.22342470 |
| 53 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.21309681 |
| 54 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.20595406 |
| 55 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.20242380 |
| 56 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.18349960 |
| 57 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.17671740 |
| 58 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.16534504 |
| 59 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.16027095 |
| 60 | AR_20517297_ChIP-Seq_VCAP_Human | 1.15739363 |
| 61 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.15402037 |
| 62 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.15331176 |
| 63 | NCOR_22424771_ChIP-Seq_293T_Human | 1.12137324 |
| 64 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.12010241 |
| 65 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.12002683 |
| 66 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.11581469 |
| 67 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.11581469 |
| 68 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.10452702 |
| 69 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.09610984 |
| 70 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.08647748 |
| 71 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.07245177 |
| 72 | P300_19829295_ChIP-Seq_ESCs_Human | 1.05188276 |
| 73 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.04987139 |
| 74 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.04952691 |
| 75 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.04415791 |
| 76 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.04191948 |
| 77 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.01170037 |
| 78 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.01140023 |
| 79 | FUS_26573619_Chip-Seq_HEK293_Human | 0.99445113 |
| 80 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.99029351 |
| 81 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.98651789 |
| 82 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.98398710 |
| 83 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.97436626 |
| 84 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.97357610 |
| 85 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.96166967 |
| 86 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.95100891 |
| 87 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.92543948 |
| 88 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.91773058 |
| 89 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.91506676 |
| 90 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.90891284 |
| 91 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.90657029 |
| 92 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.89867015 |
| 93 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.89852232 |
| 94 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.89734141 |
| 95 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.88097113 |
| 96 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.87122106 |
| 97 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.85243229 |
| 98 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.85109176 |
| 99 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.84657173 |
| 100 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.84418875 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002102_abnormal_ear_morphology | 3.50054918 |
| 2 | MP0002138_abnormal_hepatobiliary_system | 3.46872795 |
| 3 | MP0008877_abnormal_DNA_methylation | 3.45598466 |
| 4 | MP0005645_abnormal_hypothalamus_physiol | 3.28758735 |
| 5 | MP0004147_increased_porphyrin_level | 2.87232837 |
| 6 | MP0008058_abnormal_DNA_repair | 2.68479162 |
| 7 | MP0001968_abnormal_touch/_nociception | 2.49385698 |
| 8 | MP0005084_abnormal_gallbladder_morpholo | 2.45223669 |
| 9 | MP0008875_abnormal_xenobiotic_pharmacok | 2.43096761 |
| 10 | MP0005671_abnormal_response_to | 2.39076297 |
| 11 | MP0003787_abnormal_imprinting | 2.36816384 |
| 12 | MP0005075_abnormal_melanosome_morpholog | 2.34658284 |
| 13 | MP0001835_abnormal_antigen_presentation | 2.09824718 |
| 14 | MP0010094_abnormal_chromosome_stability | 2.09425158 |
| 15 | MP0000685_abnormal_immune_system | 2.05525454 |
| 16 | MP0006036_abnormal_mitochondrial_physio | 1.97645410 |
| 17 | MP0002163_abnormal_gland_morphology | 1.95751203 |
| 18 | MP0003806_abnormal_nucleotide_metabolis | 1.91909993 |
| 19 | MP0005646_abnormal_pituitary_gland | 1.90233323 |
| 20 | MP0003786_premature_aging | 1.73915780 |
| 21 | MP0005389_reproductive_system_phenotype | 1.68652829 |
| 22 | MP0003195_calcinosis | 1.64565837 |
| 23 | MP0008872_abnormal_physiological_respon | 1.61979638 |
| 24 | MP0002736_abnormal_nociception_after | 1.59428750 |
| 25 | MP0004885_abnormal_endolymph | 1.57096395 |
| 26 | MP0008007_abnormal_cellular_replicative | 1.53154599 |
| 27 | MP0002160_abnormal_reproductive_system | 1.52814172 |
| 28 | MP0002837_dystrophic_cardiac_calcinosis | 1.52380642 |
| 29 | MP0001188_hyperpigmentation | 1.51775124 |
| 30 | MP0005174_abnormal_tail_pigmentation | 1.49776383 |
| 31 | MP0009333_abnormal_splenocyte_physiolog | 1.47147486 |
| 32 | MP0000372_irregular_coat_pigmentation | 1.46389843 |
| 33 | MP0006072_abnormal_retinal_apoptosis | 1.44794071 |
| 34 | MP0004145_abnormal_muscle_electrophysio | 1.44649487 |
| 35 | MP0001986_abnormal_taste_sensitivity | 1.43843253 |
| 36 | MP0003136_yellow_coat_color | 1.41923032 |
| 37 | MP0005551_abnormal_eye_electrophysiolog | 1.41216950 |
| 38 | MP0006035_abnormal_mitochondrial_morpho | 1.41099346 |
| 39 | MP0000015_abnormal_ear_pigmentation | 1.39288368 |
| 40 | MP0008789_abnormal_olfactory_epithelium | 1.37594014 |
| 41 | MP0003646_muscle_fatigue | 1.28164009 |
| 42 | MP0005379_endocrine/exocrine_gland_phen | 1.26721290 |
| 43 | MP0003718_maternal_effect | 1.24620424 |
| 44 | MP0001529_abnormal_vocalization | 1.23589506 |
| 45 | MP0002095_abnormal_skin_pigmentation | 1.21629470 |
| 46 | MP0004215_abnormal_myocardial_fiber | 1.19719480 |
| 47 | MP0005410_abnormal_fertilization | 1.18279812 |
| 48 | MP0002272_abnormal_nervous_system | 1.17233277 |
| 49 | MP0006276_abnormal_autonomic_nervous | 1.15558910 |
| 50 | MP0006292_abnormal_olfactory_placode | 1.15390938 |
| 51 | MP0002277_abnormal_respiratory_mucosa | 1.15140645 |
| 52 | MP0001919_abnormal_reproductive_system | 1.14563020 |
| 53 | MP0003011_delayed_dark_adaptation | 1.09491588 |
| 54 | MP0003693_abnormal_embryo_hatching | 1.09487942 |
| 55 | MP0010386_abnormal_urinary_bladder | 1.06992997 |
| 56 | MP0001800_abnormal_humoral_immune | 1.05631920 |
| 57 | MP0009046_muscle_twitch | 1.04527968 |
| 58 | MP0002210_abnormal_sex_determination | 1.02631467 |
| 59 | MP0004381_abnormal_hair_follicle | 1.00825687 |
| 60 | MP0001929_abnormal_gametogenesis | 0.99953355 |
| 61 | MP0002733_abnormal_thermal_nociception | 0.97527599 |
| 62 | MP0004957_abnormal_blastocyst_morpholog | 0.96727853 |
| 63 | MP0003763_abnormal_thymus_physiology | 0.95813776 |
| 64 | MP0005387_immune_system_phenotype | 0.94365888 |
| 65 | MP0001790_abnormal_immune_system | 0.94365888 |
| 66 | MP0002148_abnormal_hypersensitivity_rea | 0.93402030 |
| 67 | MP0009745_abnormal_behavioral_response | 0.91347424 |
| 68 | MP0003137_abnormal_impulse_conducting | 0.90166517 |
| 69 | MP0005636_abnormal_mineral_homeostasis | 0.87467171 |
| 70 | MP0001905_abnormal_dopamine_level | 0.87155782 |
| 71 | MP0003121_genomic_imprinting | 0.86204477 |
| 72 | MP0003567_abnormal_fetal_cardiomyocyte | 0.83414498 |
| 73 | MP0003252_abnormal_bile_duct | 0.81710046 |
| 74 | MP0001764_abnormal_homeostasis | 0.81113525 |
| 75 | MP0000689_abnormal_spleen_morphology | 0.80571524 |
| 76 | MP0005000_abnormal_immune_tolerance | 0.80364743 |
| 77 | MP0000653_abnormal_sex_gland | 0.78766064 |
| 78 | MP0004142_abnormal_muscle_tone | 0.78423795 |
| 79 | MP0001145_abnormal_male_reproductive | 0.77837908 |
| 80 | MP0002420_abnormal_adaptive_immunity | 0.77443470 |
| 81 | MP0003045_fibrosis | 0.75951604 |
| 82 | MP0001819_abnormal_immune_cell | 0.75683404 |
| 83 | MP0001542_abnormal_bone_strength | 0.75310566 |
| 84 | MP0002452_abnormal_antigen_presenting | 0.74890293 |
| 85 | MP0001119_abnormal_female_reproductive | 0.74621159 |
| 86 | MP0001970_abnormal_pain_threshold | 0.74393394 |
| 87 | MP0005167_abnormal_blood-brain_barrier | 0.73094358 |
| 88 | MP0002229_neurodegeneration | 0.72102706 |
| 89 | MP0002723_abnormal_immune_serum | 0.71311690 |
| 90 | MP0000013_abnormal_adipose_tissue | 0.70226996 |
| 91 | MP0002938_white_spotting | 0.68847396 |
| 92 | MP0003111_abnormal_nucleus_morphology | 0.68684768 |
| 93 | MP0002166_altered_tumor_susceptibility | 0.68107230 |
| 94 | MP0009384_cardiac_valve_regurgitation | 0.67928519 |
| 95 | MP0005253_abnormal_eye_physiology | 0.67262215 |
| 96 | MP0009697_abnormal_copulation | 0.65068388 |
| 97 | MP0005394_taste/olfaction_phenotype | 0.65049793 |
| 98 | MP0005499_abnormal_olfactory_system | 0.65049793 |
| 99 | MP0002019_abnormal_tumor_incidence | 0.64308068 |
| 100 | MP0002398_abnormal_bone_marrow | 0.63053859 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Stomatitis (HP:0010280) | 6.03225061 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 4.33484011 |
| 3 | Increased IgM level (HP:0003496) | 4.12366139 |
| 4 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.91951074 |
| 5 | IgG deficiency (HP:0004315) | 3.80656410 |
| 6 | Mitochondrial inheritance (HP:0001427) | 3.73355909 |
| 7 | Progressive macrocephaly (HP:0004481) | 3.67359632 |
| 8 | Increased CSF lactate (HP:0002490) | 3.62962514 |
| 9 | Acute encephalopathy (HP:0006846) | 3.62691734 |
| 10 | Congenital stationary night blindness (HP:0007642) | 3.34786257 |
| 11 | Abnormality of T cell physiology (HP:0011840) | 3.01837833 |
| 12 | Abnormality of alanine metabolism (HP:0010916) | 2.99178762 |
| 13 | Hyperalaninemia (HP:0003348) | 2.99178762 |
| 14 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.99178762 |
| 15 | Type 2 muscle fiber atrophy (HP:0003554) | 2.99160739 |
| 16 | 3-Methylglutaconic aciduria (HP:0003535) | 2.95058425 |
| 17 | Methylmalonic aciduria (HP:0012120) | 2.89442301 |
| 18 | Hepatocellular necrosis (HP:0001404) | 2.88298436 |
| 19 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.87287621 |
| 20 | Methylmalonic acidemia (HP:0002912) | 2.87216769 |
| 21 | Congenital, generalized hypertrichosis (HP:0004540) | 2.81314213 |
| 22 | Pancreatic cysts (HP:0001737) | 2.81003827 |
| 23 | Colon cancer (HP:0003003) | 2.75462455 |
| 24 | Hepatic necrosis (HP:0002605) | 2.75085994 |
| 25 | Abnormality of the prostate (HP:0008775) | 2.74626694 |
| 26 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.73508944 |
| 27 | Cerebral edema (HP:0002181) | 2.72914674 |
| 28 | Polydipsia (HP:0001959) | 2.67570664 |
| 29 | Abnormal drinking behavior (HP:0030082) | 2.67570664 |
| 30 | Renal cortical cysts (HP:0000803) | 2.65735636 |
| 31 | IgA deficiency (HP:0002720) | 2.65592895 |
| 32 | Decreased circulating renin level (HP:0003351) | 2.65388472 |
| 33 | Pancreatic fibrosis (HP:0100732) | 2.61999701 |
| 34 | Increased hepatocellular lipid droplets (HP:0006565) | 2.53698282 |
| 35 | Optic disc pallor (HP:0000543) | 2.49272761 |
| 36 | Abnormality of the labia minora (HP:0012880) | 2.46601205 |
| 37 | Multiple enchondromatosis (HP:0005701) | 2.37337634 |
| 38 | Increased serum lactate (HP:0002151) | 2.36980193 |
| 39 | True hermaphroditism (HP:0010459) | 2.36497325 |
| 40 | Aplastic anemia (HP:0001915) | 2.35294305 |
| 41 | Lethargy (HP:0001254) | 2.34713870 |
| 42 | Abnormality of the renal cortex (HP:0011035) | 2.33915272 |
| 43 | Abnormality of T cells (HP:0002843) | 2.33626574 |
| 44 | Lipid accumulation in hepatocytes (HP:0006561) | 2.32780100 |
| 45 | Type II lissencephaly (HP:0007260) | 2.31167250 |
| 46 | Muscle fiber atrophy (HP:0100295) | 2.29541984 |
| 47 | Polyuria (HP:0000103) | 2.26301594 |
| 48 | Abnormality of DNA repair (HP:0003254) | 2.25395522 |
| 49 | Lactic acidosis (HP:0003128) | 2.20673465 |
| 50 | Abnormality of midbrain morphology (HP:0002418) | 2.17157503 |
| 51 | Molar tooth sign on MRI (HP:0002419) | 2.17157503 |
| 52 | Abnormality of male internal genitalia (HP:0000022) | 2.13459752 |
| 53 | Short tibia (HP:0005736) | 2.12254182 |
| 54 | Progressive microcephaly (HP:0000253) | 2.09287400 |
| 55 | Respiratory failure (HP:0002878) | 2.08195778 |
| 56 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.07931517 |
| 57 | Dicarboxylic aciduria (HP:0003215) | 2.07931517 |
| 58 | Oral leukoplakia (HP:0002745) | 2.07410931 |
| 59 | Increased intramyocellular lipid droplets (HP:0012240) | 2.06970705 |
| 60 | Neutropenia (HP:0001875) | 2.06459386 |
| 61 | Attenuation of retinal blood vessels (HP:0007843) | 2.05533039 |
| 62 | Decreased central vision (HP:0007663) | 2.05382715 |
| 63 | Abnormality of B cell number (HP:0010975) | 2.05031049 |
| 64 | Pancytopenia (HP:0001876) | 2.04697786 |
| 65 | Exertional dyspnea (HP:0002875) | 2.03549301 |
| 66 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.03446317 |
| 67 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.00411711 |
| 68 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.99044973 |
| 69 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.95674762 |
| 70 | Prostate neoplasm (HP:0100787) | 1.94431065 |
| 71 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.92770606 |
| 72 | Mesangial abnormality (HP:0001966) | 1.92738697 |
| 73 | Abolished electroretinogram (ERG) (HP:0000550) | 1.92566870 |
| 74 | Leukodystrophy (HP:0002415) | 1.90610740 |
| 75 | Pendular nystagmus (HP:0012043) | 1.90285729 |
| 76 | Nephronophthisis (HP:0000090) | 1.86692252 |
| 77 | Ketosis (HP:0001946) | 1.81232436 |
| 78 | Tinnitus (HP:0000360) | 1.80900998 |
| 79 | Abnormal urine output (HP:0012590) | 1.79707875 |
| 80 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 1.78769527 |
| 81 | Hypoplasia of the fovea (HP:0007750) | 1.78769527 |
| 82 | Cleft eyelid (HP:0000625) | 1.78476507 |
| 83 | Severe combined immunodeficiency (HP:0004430) | 1.78152462 |
| 84 | Abnormality of homocysteine metabolism (HP:0010919) | 1.78036159 |
| 85 | Homocystinuria (HP:0002156) | 1.78036159 |
| 86 | Limb dystonia (HP:0002451) | 1.77651514 |
| 87 | Abnormality of serum amino acid levels (HP:0003112) | 1.77122215 |
| 88 | Hypoplasia of the uterus (HP:0000013) | 1.76984446 |
| 89 | Renal Fanconi syndrome (HP:0001994) | 1.76381102 |
| 90 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.76348827 |
| 91 | Respiratory difficulties (HP:0002880) | 1.74905947 |
| 92 | Cerebellar dysplasia (HP:0007033) | 1.72149719 |
| 93 | Supernumerary spleens (HP:0009799) | 1.70836101 |
| 94 | Hyperglycinemia (HP:0002154) | 1.70716383 |
| 95 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.69157466 |
| 96 | B lymphocytopenia (HP:0010976) | 1.68341537 |
| 97 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.68094823 |
| 98 | Asplenia (HP:0001746) | 1.68060773 |
| 99 | Abnormality of renin-angiotensin system (HP:0000847) | 1.67816899 |
| 100 | Central scotoma (HP:0000603) | 1.65877953 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STK16 | 4.37248944 |
| 2 | NUAK1 | 3.69442903 |
| 3 | TXK | 3.54835811 |
| 4 | VRK2 | 3.16015122 |
| 5 | ADRBK2 | 2.36119473 |
| 6 | TAOK3 | 2.29864463 |
| 7 | ZAK | 2.29810751 |
| 8 | EIF2AK3 | 2.29311871 |
| 9 | GRK1 | 2.28832855 |
| 10 | BUB1 | 2.22073069 |
| 11 | EIF2AK1 | 2.15776611 |
| 12 | NEK1 | 2.06635805 |
| 13 | WNK4 | 2.03065526 |
| 14 | PDK2 | 2.00018192 |
| 15 | VRK1 | 1.99469254 |
| 16 | TLK1 | 1.89938723 |
| 17 | BMPR1B | 1.82809957 |
| 18 | OXSR1 | 1.81844092 |
| 19 | FRK | 1.79197528 |
| 20 | PLK4 | 1.78694130 |
| 21 | STK39 | 1.77459351 |
| 22 | MKNK2 | 1.66345690 |
| 23 | KDR | 1.56789947 |
| 24 | MKNK1 | 1.53699471 |
| 25 | TESK2 | 1.53365774 |
| 26 | WNK3 | 1.49966534 |
| 27 | PLK3 | 1.41833574 |
| 28 | EIF2AK2 | 1.37108869 |
| 29 | MST4 | 1.36481325 |
| 30 | CSNK1G3 | 1.16406873 |
| 31 | DAPK1 | 1.15967958 |
| 32 | GRK5 | 1.13848764 |
| 33 | TSSK6 | 1.12161442 |
| 34 | MAP4K2 | 1.08516679 |
| 35 | IKBKB | 1.05663113 |
| 36 | CSNK1G1 | 1.02578366 |
| 37 | GRK7 | 1.00673587 |
| 38 | PLK2 | 0.98609480 |
| 39 | CCNB1 | 0.95779112 |
| 40 | BRSK2 | 0.95420454 |
| 41 | SRPK1 | 0.94489440 |
| 42 | DYRK2 | 0.89849273 |
| 43 | NME1 | 0.88382588 |
| 44 | TAF1 | 0.88215291 |
| 45 | PHKG1 | 0.86824460 |
| 46 | PHKG2 | 0.86824460 |
| 47 | KIT | 0.86480386 |
| 48 | MAPKAPK5 | 0.85208399 |
| 49 | CSNK1A1L | 0.84984077 |
| 50 | CSNK1G2 | 0.82745325 |
| 51 | BCKDK | 0.82718983 |
| 52 | SYK | 0.77481522 |
| 53 | DAPK2 | 0.75167277 |
| 54 | WEE1 | 0.74992613 |
| 55 | PRKCQ | 0.74961236 |
| 56 | TGFBR2 | 0.74927961 |
| 57 | TIE1 | 0.73098654 |
| 58 | ADRBK1 | 0.70481856 |
| 59 | ITK | 0.70404439 |
| 60 | RPS6KA5 | 0.70318105 |
| 61 | MAPK13 | 0.69278363 |
| 62 | INSRR | 0.69252468 |
| 63 | PRKCG | 0.67386299 |
| 64 | CDC7 | 0.60482310 |
| 65 | TTK | 0.58071636 |
| 66 | PLK1 | 0.57622513 |
| 67 | ACVR1B | 0.55641783 |
| 68 | IKBKE | 0.53472175 |
| 69 | ATR | 0.51009014 |
| 70 | TEC | 0.49998313 |
| 71 | IGF1R | 0.47873261 |
| 72 | LIMK1 | 0.47399855 |
| 73 | TESK1 | 0.46239750 |
| 74 | AURKB | 0.44587285 |
| 75 | LCK | 0.42477753 |
| 76 | BMPR2 | 0.41949415 |
| 77 | CAMKK2 | 0.40840025 |
| 78 | CSNK1A1 | 0.39539482 |
| 79 | PRKCI | 0.39390562 |
| 80 | PINK1 | 0.38654718 |
| 81 | PRKACA | 0.37723333 |
| 82 | PRKCE | 0.36973730 |
| 83 | CSNK2A1 | 0.36457724 |
| 84 | MAP2K2 | 0.36068055 |
| 85 | CSNK2A2 | 0.35477249 |
| 86 | OBSCN | 0.35341680 |
| 87 | NTRK3 | 0.34591857 |
| 88 | ALK | 0.34213510 |
| 89 | CHEK2 | 0.33315987 |
| 90 | RAF1 | 0.33244133 |
| 91 | CSNK1D | 0.32720875 |
| 92 | MINK1 | 0.32384034 |
| 93 | LYN | 0.31749447 |
| 94 | ATM | 0.31040924 |
| 95 | MAPKAPK3 | 0.29356792 |
| 96 | PRKCD | 0.29059835 |
| 97 | ABL1 | 0.28991919 |
| 98 | CDK3 | 0.28058255 |
| 99 | TNK2 | 0.27999125 |
| 100 | MUSK | 0.27746641 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.33968684 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.24181283 |
| 3 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 2.97676826 |
| 4 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.87471167 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 2.87149294 |
| 6 | Protein export_Homo sapiens_hsa03060 | 2.61672901 |
| 7 | Ribosome_Homo sapiens_hsa03010 | 2.51187068 |
| 8 | Mismatch repair_Homo sapiens_hsa03430 | 2.31655160 |
| 9 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.29399315 |
| 10 | Homologous recombination_Homo sapiens_hsa03440 | 2.25070806 |
| 11 | Asthma_Homo sapiens_hsa05310 | 2.20236447 |
| 12 | DNA replication_Homo sapiens_hsa03030 | 2.13437433 |
| 13 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.12271124 |
| 14 | RNA polymerase_Homo sapiens_hsa03020 | 2.01651507 |
| 15 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.99429936 |
| 16 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.92480337 |
| 17 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.91346141 |
| 18 | Allograft rejection_Homo sapiens_hsa05330 | 1.82518876 |
| 19 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.78849550 |
| 20 | Alzheimers disease_Homo sapiens_hsa05010 | 1.78610652 |
| 21 | Phototransduction_Homo sapiens_hsa04744 | 1.77095837 |
| 22 | Huntingtons disease_Homo sapiens_hsa05016 | 1.74338066 |
| 23 | Basal transcription factors_Homo sapiens_hsa03022 | 1.71980412 |
| 24 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.70409802 |
| 25 | RNA degradation_Homo sapiens_hsa03018 | 1.60698083 |
| 26 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.51595279 |
| 27 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.50589883 |
| 28 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.45093103 |
| 29 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.39104404 |
| 30 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.36748853 |
| 31 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.35678520 |
| 32 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.34844128 |
| 33 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.34569157 |
| 34 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.33909816 |
| 35 | RNA transport_Homo sapiens_hsa03013 | 1.28321277 |
| 36 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.28286649 |
| 37 | Base excision repair_Homo sapiens_hsa03410 | 1.27986190 |
| 38 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.13127536 |
| 39 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.10599118 |
| 40 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.08533647 |
| 41 | Purine metabolism_Homo sapiens_hsa00230 | 1.06316492 |
| 42 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.04794756 |
| 43 | Peroxisome_Homo sapiens_hsa04146 | 1.04236706 |
| 44 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.02464484 |
| 45 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.02376573 |
| 46 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.01667265 |
| 47 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.95305955 |
| 48 | Spliceosome_Homo sapiens_hsa03040 | 0.94648368 |
| 49 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.92419814 |
| 50 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.89292302 |
| 51 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.85843521 |
| 52 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.84671702 |
| 53 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.83227870 |
| 54 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.79745884 |
| 55 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.73561753 |
| 56 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.72415248 |
| 57 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.72324764 |
| 58 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.71933132 |
| 59 | Olfactory transduction_Homo sapiens_hsa04740 | 0.71810066 |
| 60 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.71076350 |
| 61 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.69489687 |
| 62 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.67409939 |
| 63 | Retinol metabolism_Homo sapiens_hsa00830 | 0.66379679 |
| 64 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.65780564 |
| 65 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.65181900 |
| 66 | Viral myocarditis_Homo sapiens_hsa05416 | 0.60900329 |
| 67 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.59832816 |
| 68 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.59705644 |
| 69 | Metabolic pathways_Homo sapiens_hsa01100 | 0.59385227 |
| 70 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.59003546 |
| 71 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.58042695 |
| 72 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.56420126 |
| 73 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.53611720 |
| 74 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.51348618 |
| 75 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.50763608 |
| 76 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.48377846 |
| 77 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.46472714 |
| 78 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.46340412 |
| 79 | Nicotine addiction_Homo sapiens_hsa05033 | 0.44838317 |
| 80 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.42757833 |
| 81 | Taste transduction_Homo sapiens_hsa04742 | 0.41567857 |
| 82 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.39783107 |
| 83 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.38941661 |
| 84 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.38191884 |
| 85 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.37481131 |
| 86 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.36049740 |
| 87 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.34912662 |
| 88 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.34149857 |
| 89 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.31922780 |
| 90 | Morphine addiction_Homo sapiens_hsa05032 | 0.31363257 |
| 91 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.30084157 |
| 92 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.29610602 |
| 93 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.28861894 |
| 94 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.28153763 |
| 95 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.28111282 |
| 96 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.27916490 |
| 97 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.26259668 |
| 98 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.26158595 |
| 99 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.25937430 |
| 100 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.24160875 |

