HACD4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G8.58709144
2neutrophil activation involved in immune response (GO:0002283)5.27119643
3platelet dense granule organization (GO:0060155)5.04513325
4definitive hemopoiesis (GO:0060216)5.03780226
5production of molecular mediator involved in inflammatory response (GO:0002532)4.90514909
6response to interferon-alpha (GO:0035455)4.79877585
7negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.75212006
8negative regulation of cell killing (GO:0031342)4.75212006
9response to interferon-beta (GO:0035456)4.72244556
10ribosomal small subunit assembly (GO:0000028)4.52094872
11response to peptidoglycan (GO:0032494)4.36048744
12modulation by symbiont of host defense response (GO:0052031)4.34049644
13modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.34049644
14modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.34049644
15positive regulation by organism of defense response of other organism involved in symbiotic interact4.34049644
16modulation by symbiont of host immune response (GO:0052553)4.34049644
17positive regulation by symbiont of host defense response (GO:0052509)4.34049644
18regulation of interferon-beta biosynthetic process (GO:0045357)4.32240888
19regulation of B cell receptor signaling pathway (GO:0050855)4.04510590
20regulation of gamma-delta T cell activation (GO:0046643)4.02459399
21endosome to pigment granule transport (GO:0043485)3.93096578
22endosome to melanosome transport (GO:0035646)3.93096578
23cellular response to type I interferon (GO:0071357)3.91312073
24type I interferon signaling pathway (GO:0060337)3.91312073
25detection of bacterium (GO:0016045)3.91238775
26immunoglobulin mediated immune response (GO:0016064)3.90711604
27response to type I interferon (GO:0034340)3.90588875
28antigen processing and presentation via MHC class Ib (GO:0002475)3.89578594
29positive regulation of gamma-delta T cell activation (GO:0046645)3.84230246
30negative regulation of viral genome replication (GO:0045071)3.83101850
31megakaryocyte development (GO:0035855)3.81184946
32negative regulation of erythrocyte differentiation (GO:0045647)3.78837428
33positive regulation of interferon-alpha production (GO:0032727)3.76057161
34leukocyte migration involved in inflammatory response (GO:0002523)3.67974127
35cellular response to thyroid hormone stimulus (GO:0097067)3.66532284
36regulation of gamma-delta T cell differentiation (GO:0045586)3.66267081
37B cell receptor signaling pathway (GO:0050853)3.63346249
38respiratory burst (GO:0045730)3.60243903
39regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.59650119
40mature B cell differentiation involved in immune response (GO:0002313)3.57549925
41negative regulation of lymphocyte mediated immunity (GO:0002707)3.52079255
42regulation of interferon-alpha production (GO:0032647)3.52048467
43macrophage activation involved in immune response (GO:0002281)3.51748914
44positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.51601113
45neutrophil activation (GO:0042119)3.51313390
46myeloid cell activation involved in immune response (GO:0002275)3.48464451
47positive regulation of granulocyte differentiation (GO:0030854)3.47062434
48positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.46985346
49positive regulation of B cell differentiation (GO:0045579)3.46815334
50negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.43350866
51granulocyte activation (GO:0036230)3.43189347
52response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.41657869
53response to host immune response (GO:0052572)3.41657869
54negative regulation of interleukin-12 production (GO:0032695)3.39953039
55regulation of alpha-beta T cell proliferation (GO:0046640)3.37201324
56defense response to protozoan (GO:0042832)3.36381085
57detection of other organism (GO:0098543)3.35761937
58regulation of tolerance induction (GO:0002643)3.34552883
59regulation of T-helper 1 cell differentiation (GO:0045625)3.33832779
60leukocyte aggregation (GO:0070486)3.32906128
61regulation of mast cell activation (GO:0033003)3.32135050
62cellular extravasation (GO:0045123)3.31839104
63phagocytosis, engulfment (GO:0006911)3.31431929
64negative regulation of T cell mediated immunity (GO:0002710)3.30966221
65detection of biotic stimulus (GO:0009595)3.29474390
66detection of molecule of bacterial origin (GO:0032490)3.29470437
67regulation of platelet aggregation (GO:0090330)3.29380208
68negative thymic T cell selection (GO:0045060)3.28712071
69negative T cell selection (GO:0043383)3.28458380
70regulation of mast cell degranulation (GO:0043304)3.26039123
71tolerance induction (GO:0002507)3.24754362
72regulation of interleukin-12 biosynthetic process (GO:0045075)3.23915980
73regulation of myeloid leukocyte mediated immunity (GO:0002886)3.23022707
74regulation of syncytium formation by plasma membrane fusion (GO:0060142)3.21956491
75interferon-gamma-mediated signaling pathway (GO:0060333)3.19864665
76mast cell activation (GO:0045576)3.18366740
77negative regulation of T-helper cell differentiation (GO:0045623)3.18159691
78negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)3.18159691
79positive regulation of natural killer cell differentiation (GO:0032825)3.17768189
80negative regulation of interleukin-17 production (GO:0032700)3.16998897
81neutrophil mediated immunity (GO:0002446)3.16730659
82mature B cell differentiation (GO:0002335)3.16122048
83regulation of regulatory T cell differentiation (GO:0045589)3.16040187
84Arp2/3 complex-mediated actin nucleation (GO:0034314)3.14060427
85response to protozoan (GO:0001562)3.12855581
86G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)3.12635880
87positive regulation of interferon-beta production (GO:0032728)3.11613797
88positive thymic T cell selection (GO:0045059)3.11383373
89lipopolysaccharide-mediated signaling pathway (GO:0031663)3.09139880
90negative regulation of leukocyte mediated immunity (GO:0002704)3.07753502
91thrombin receptor signaling pathway (GO:0070493)3.07077931
92response to host (GO:0075136)3.07013060
93response to host defenses (GO:0052200)3.07013060
94response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.07013060
95response to interleukin-15 (GO:0070672)3.06578156
96regulation of mast cell activation involved in immune response (GO:0033006)3.06184229
97regulation of leukocyte degranulation (GO:0043300)3.06009444
98antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.05894785
99antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.05894785
100secretory granule organization (GO:0033363)3.04128921
101activated T cell proliferation (GO:0050798)3.03206608
102response to muramyl dipeptide (GO:0032495)3.02422867
103polyketide metabolic process (GO:0030638)3.01676791
104doxorubicin metabolic process (GO:0044598)3.01676791
105daunorubicin metabolic process (GO:0044597)3.01676791
106regulation of germinal center formation (GO:0002634)3.00356874
107B cell mediated immunity (GO:0019724)3.00254595
108positive regulation of myeloid leukocyte mediated immunity (GO:0002888)3.00044414
109pinocytosis (GO:0006907)2.98921971
110positive regulation of alpha-beta T cell proliferation (GO:0046641)2.97357483
111positive regulation of mast cell activation (GO:0033005)2.96851398
112positive regulation of tolerance induction (GO:0002645)2.94999611
113regulation of B cell differentiation (GO:0045577)2.94478023
114myeloid dendritic cell activation (GO:0001773)2.94472986
115positive regulation of antigen processing and presentation (GO:0002579)2.92800554
116regulation of interleukin-17 production (GO:0032660)2.91162476
117negative regulation of viral entry into host cell (GO:0046597)2.90833284
118regulation of hypersensitivity (GO:0002883)2.90425449
119regulation of natural killer cell differentiation (GO:0032823)2.90158440
120negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.90099858
121T-helper 1 type immune response (GO:0042088)2.90025934
122positive regulation of B cell mediated immunity (GO:0002714)2.88976923
123positive regulation of immunoglobulin mediated immune response (GO:0002891)2.88976923
124T cell migration (GO:0072678)2.88547176
125detection of external biotic stimulus (GO:0098581)2.88344434
126positive regulation of macrophage differentiation (GO:0045651)2.88097535
127microglial cell activation (GO:0001774)2.87095774
128positive regulation of lymphocyte migration (GO:2000403)2.86292947
129positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.85633942
130regulation of platelet activation (GO:0010543)2.85608388
131dendritic cell migration (GO:0036336)2.84819882
132antigen receptor-mediated signaling pathway (GO:0050851)2.84720267
133positive T cell selection (GO:0043368)2.84359068
134leukocyte degranulation (GO:0043299)2.83311332
135positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.83259984
136superoxide anion generation (GO:0042554)2.82478621
137myeloid leukocyte activation (GO:0002274)2.82349503
138positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.82263474
139positive regulation of interleukin-17 production (GO:0032740)2.81924243
140cellular response to interleukin-15 (GO:0071350)2.81710659
141positive regulation of mast cell activation involved in immune response (GO:0033008)2.80334491
142positive regulation of mast cell degranulation (GO:0043306)2.80334491
143regulation of T cell tolerance induction (GO:0002664)2.80085692
144response to thyroid hormone (GO:0097066)2.79635064
145macrophage differentiation (GO:0030225)2.79279688
146cellular response to interferon-beta (GO:0035458)2.79264384
147antigen processing and presentation of endogenous antigen (GO:0019883)2.77640159
148regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.77632091
149lymph node development (GO:0048535)2.77212628
150negative regulation of nitric oxide biosynthetic process (GO:0045019)2.77087473
151macrophage activation (GO:0042116)2.75653305

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human7.58390910
2IRF8_21731497_ChIP-ChIP_J774_Mouse5.67544793
3IRF8_22096565_ChIP-ChIP_GC-B_Human5.42872585
4SCL_19346495_ChIP-Seq_HPC-7_Human4.54731813
5MECOM_23826213_ChIP-Seq_KASUMI_Mouse4.36236157
6IRF8_27001747_Chip-Seq_BMDM_Mouse3.94479177
7IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.94156743
8SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.91620681
9NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.44101060
10MYB_21317192_ChIP-Seq_ERMYB_Mouse3.36014468
11Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse3.31514804
12RUNX1_20887958_ChIP-Seq_HPC-7_Mouse3.22734434
13IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.11556163
14FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.09390974
15SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.96233364
16STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.91805560
17SPI1_23547873_ChIP-Seq_NB4_Human2.72032948
18LYL1_20887958_ChIP-Seq_HPC-7_Mouse2.56901240
19STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.35342602
20GATA2_21666600_ChIP-Seq_HMVEC_Human2.31707095
21SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.29801043
22STAT4_19710469_ChIP-ChIP_TH1__Mouse2.26240557
23LMO2_20887958_ChIP-Seq_HPC-7_Mouse2.26025563
24FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.22628028
25MEIS1_20887958_ChIP-Seq_HPC-7_Mouse2.19720363
26NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.12097310
27SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.08795536
28RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.01356419
29VDR_24763502_ChIP-Seq_THP-1_Human1.96380109
30RUNX1_22412390_ChIP-Seq_EML_Mouse1.93485511
31BRD4_27068464_Chip-Seq_AML-cells_Mouse1.88950525
32RUNX_20019798_ChIP-Seq_JUKART_Human1.85987273
33CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.84715322
34CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.78236736
35PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.76396369
36SPI1_23127762_ChIP-Seq_K562_Human1.75439322
37MYB_26560356_Chip-Seq_TH2_Human1.71422739
38PU_27001747_Chip-Seq_BMDM_Mouse1.70431199
39GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.67810066
40FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.67146098
41TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.66024542
42ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.65320659
43CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.58412889
44GATA2_22383799_ChIP-Seq_G1ME_Mouse1.55593889
45STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.55408117
46GATA1_22025678_ChIP-Seq_K562_Human1.51594986
47CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.45973932
48VDR_21846776_ChIP-Seq_THP-1_Human1.44962277
49SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.43386852
50SMAD_19615063_ChIP-ChIP_OVARY_Human1.43102793
51HOXB4_20404135_ChIP-ChIP_EML_Mouse1.42222414
52PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.41815023
53MYB_26560356_Chip-Seq_TH1_Human1.38125889
54MAF_26560356_Chip-Seq_TH1_Human1.37471179
55THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.35432999
56VDR_24787735_ChIP-Seq_THP-1_Human1.34997990
57ELF1_17652178_ChIP-ChIP_JURKAT_Human1.34060171
58GATA1_19941827_ChIP-Seq_MEL_Mouse1.33834555
59ERG_20887958_ChIP-Seq_HPC-7_Mouse1.31924508
60STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.29668411
61SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.27940980
62PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.25412592
63NOTCH1_21737748_ChIP-Seq_TLL_Human1.24873665
64GATA1_22383799_ChIP-Seq_G1ME_Mouse1.22905630
65CDX2_19796622_ChIP-Seq_MESCs_Mouse1.21788675
66CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.20794989
67CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.17430625
68GATA3_26560356_Chip-Seq_TH2_Human1.15017762
69SMRT_27268052_Chip-Seq_Bcells_Human1.11102986
70GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.09830087
71IKZF1_21737484_ChIP-ChIP_HCT116_Human1.08015330
72PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.06510618
73RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.04368715
74TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.04278099
75HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.03876696
76BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.01364807
77CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.00493780
78GATA3_27048872_Chip-Seq_THYMUS_Human1.00081224
79E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.99933088
80UTX_26944678_Chip-Seq_JUKART_Human0.99292916
81CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.98066255
82GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.96885610
83FLI1_27457419_Chip-Seq_LIVER_Mouse0.95581787
84RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.94607418
85FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.93857906
86SOX2_20726797_ChIP-Seq_SW620_Human0.91962961
87GATA1_19941827_ChIP-Seq_MEL86_Mouse0.91055917
88GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91036776
89TCF7_22412390_ChIP-Seq_EML_Mouse0.90659911
90GATA2_19941826_ChIP-Seq_K562_Human0.90005890
91SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.89288234
92GATA1_19941826_ChIP-Seq_K562_Human0.88031307
93MAF_26560356_Chip-Seq_TH2_Human0.87612457
94PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.84895106
95ETS1_22383799_ChIP-Seq_G1ME_Mouse0.83607266
96EGR1_19032775_ChIP-ChIP_M12_Human0.83455474
97TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.81386735
98TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.80989629
99STAT1_20625510_ChIP-Seq_HELA_Human0.80839880
100VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.80482600
101ELK1_19687146_ChIP-ChIP_HELA_Human0.80229799
102EGR1_19374776_ChIP-ChIP_THP-1_Human0.79839161
103CDX2_20551321_ChIP-Seq_CACO-2_Human0.79053282
104SALL4_22934838_ChIP-ChIP_CD34+_Human0.77604695
105ELK3_25401928_ChIP-Seq_HUVEC_Human0.76953609
106GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.76747479
107IGF1R_20145208_ChIP-Seq_DFB_Human0.76130023
108GATA3_26560356_Chip-Seq_TH1_Human0.75999229
109VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.75349424
110EGR1_23403033_ChIP-Seq_LIVER_Mouse0.74930984
111GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.74804086
112CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.72483304
113FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.72116907
114KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.71962588
115NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.71913565
116TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.69010432
117PCGF2_27294783_Chip-Seq_ESCs_Mouse0.68959178
118ER_23166858_ChIP-Seq_MCF-7_Human0.68751845
119PRDM14_20953172_ChIP-Seq_ESCs_Human0.68118585
120NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.67956341
121NRF2_20460467_ChIP-Seq_MEFs_Mouse0.67956341
122RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.67564792
123POU3F2_20337985_ChIP-ChIP_501MEL_Human0.66507010
124SPI1_20517297_ChIP-Seq_HL60_Human0.65658733
125SRF_21415370_ChIP-Seq_HL-1_Mouse0.61509492

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.04603665
2MP0003436_decreased_susceptibility_to3.69774151
3MP0009785_altered_susceptibility_to3.45161501
4MP0002148_abnormal_hypersensitivity_rea3.42055082
5MP0003724_increased_susceptibility_to3.40284108
6MP0002419_abnormal_innate_immunity3.07716063
7MP0005464_abnormal_platelet_physiology2.92737826
8MP0005025_abnormal_response_to2.81943179
9MP0005000_abnormal_immune_tolerance2.80463389
10MP0005058_abnormal_lysosome_morphology2.55228773
11MP0002452_abnormal_antigen_presenting2.51645918
12MP0005174_abnormal_tail_pigmentation2.48792683
13MP0005671_abnormal_response_to2.46650284
14MP0000685_abnormal_immune_system2.46294433
15MP0006082_CNS_inflammation2.34994454
16MP0002723_abnormal_immune_serum2.29254558
17MP0001800_abnormal_humoral_immune2.27009606
18MP0003763_abnormal_thymus_physiology2.26651689
19MP0004808_abnormal_hematopoietic_stem2.24930240
20MP0000343_altered_response_to2.20065978
21MP0001790_abnormal_immune_system2.17404071
22MP0005387_immune_system_phenotype2.17404071
23MP0001819_abnormal_immune_cell2.16804784
24MP0002420_abnormal_adaptive_immunity2.16793867
25MP0009278_abnormal_bone_marrow2.12259978
26MP0000465_gastrointestinal_hemorrhage2.09614934
27MP0003191_abnormal_cellular_cholesterol2.09582563
28MP0001533_abnormal_skeleton_physiology2.08939841
29MP0002396_abnormal_hematopoietic_system2.01684999
30MP0005397_hematopoietic_system_phenotyp1.93322285
31MP0001545_abnormal_hematopoietic_system1.93322285
32MP0003303_peritoneal_inflammation1.89747601
33MP0004510_myositis1.88005028
34MP0001853_heart_inflammation1.76522371
35MP0002405_respiratory_system_inflammati1.75775658
36MP0001845_abnormal_inflammatory_respons1.70050540
37MP0003075_altered_response_to1.68348963
38MP0010155_abnormal_intestine_physiology1.67033342
39MP0003279_aneurysm1.64604270
40MP0009764_decreased_sensitivity_to1.62646398
41MP0003828_pulmonary_edema1.62525948
42MP0002398_abnormal_bone_marrow1.60844449
43MP0000716_abnormal_immune_system1.60292295
44MP0003183_abnormal_peptide_metabolism1.55537768
45MP0000689_abnormal_spleen_morphology1.52257046
46MP0003172_abnormal_lysosome_physiology1.52186249
47MP0008469_abnormal_protein_level1.50673498
48MP0001958_emphysema1.43739909
49MP0005167_abnormal_blood-brain_barrier1.42867240
50MP0010368_abnormal_lymphatic_system1.39148018
51MP0002429_abnormal_blood_cell1.37798658
52MP0000703_abnormal_thymus_morphology1.37626345
53MP0002166_altered_tumor_susceptibility1.36525916
54MP0002006_tumorigenesis1.34508521
55MP0000015_abnormal_ear_pigmentation1.33676329
56MP0000490_abnormal_crypts_of1.32678793
57MP0008438_abnormal_cutaneous_collagen1.30814428
58MP0002722_abnormal_immune_system1.30254236
59MP0005166_decreased_susceptibility_to1.26292565
60MP0002998_abnormal_bone_remodeling1.23949842
61MP0005390_skeleton_phenotype1.23540119
62MP0009333_abnormal_splenocyte_physiolog1.22583881
63MP0004947_skin_inflammation1.22072829
64MP0003448_altered_tumor_morphology1.21892401
65MP0002095_abnormal_skin_pigmentation1.20737897
66MP0002933_joint_inflammation1.18273010
67MP0005164_abnormal_response_to1.18130786
68MP0004381_abnormal_hair_follicle1.16828468
69MP0006054_spinal_hemorrhage1.16454100
70MP0001879_abnormal_lymphatic_vessel1.12887100
71MP0005310_abnormal_salivary_gland1.12755068
72MP0009379_abnormal_foot_pigmentation1.04851020
73MP0000569_abnormal_digit_pigmentation1.04487110
74MP0008260_abnormal_autophagy1.02242154
75MP0000372_irregular_coat_pigmentation0.96814633
76MP0005075_abnormal_melanosome_morpholog0.94765696
77MP0001851_eye_inflammation0.94762363
78MP0003690_abnormal_glial_cell0.91534004
79MP0009763_increased_sensitivity_to0.91473922
80MP0003045_fibrosis0.90493982
81MP0004883_abnormal_blood_vessel0.89873678
82MP0000858_altered_metastatic_potential0.89601294
83MP0000249_abnormal_blood_vessel0.89568639
84MP0002877_abnormal_melanocyte_morpholog0.89091767
85MP0001986_abnormal_taste_sensitivity0.88790903
86MP0008004_abnormal_stomach_pH0.87708960
87MP0003656_abnormal_erythrocyte_physiolo0.86766856
88MP0009765_abnormal_xenobiotic_induced0.86627780
89MP0004130_abnormal_muscle_cell0.86447160
90MP0000767_abnormal_smooth_muscle0.85610633
91MP0005084_abnormal_gallbladder_morpholo0.79679567
92MP0002132_abnormal_respiratory_system0.79313776
93MP0005083_abnormal_biliary_tract0.77230217
94MP0003866_abnormal_defecation0.77149385
95MP0002277_abnormal_respiratory_mucosa0.75769589
96MP0003795_abnormal_bone_structure0.75694138
97MP0003943_abnormal_hepatobiliary_system0.75332610
98MP0004782_abnormal_surfactant_physiolog0.74298887
99MP0003011_delayed_dark_adaptation0.73954939
100MP0003136_yellow_coat_color0.73381989
101MP0003566_abnormal_cell_adhesion0.71148915
102MP0001873_stomach_inflammation0.70091236
103MP0001765_abnormal_ion_homeostasis0.69318518
104MP0000230_abnormal_systemic_arterial0.69168257
105MP0003252_abnormal_bile_duct0.67543473
106MP0004484_altered_response_of0.67326820
107MP0000371_diluted_coat_color0.66654701
108MP0009840_abnormal_foam_cell0.66485754
109MP0005409_darkened_coat_color0.65463280
110MP0001663_abnormal_digestive_system0.65364093
111MP0003300_gastrointestinal_ulcer0.65111839
112MP0004147_increased_porphyrin_level0.64681222
113MP0002009_preneoplasia0.63903732
114MP0003806_abnormal_nucleotide_metabolis0.62630828
115MP0003638_abnormal_response/metabolism_0.62330379
116MP0003186_abnormal_redox_activity0.61652644
117MP0002019_abnormal_tumor_incidence0.56715183
118MP0009642_abnormal_blood_homeostasis0.54001591
119MP0008874_decreased_physiological_sensi0.53465877
120MP0005535_abnormal_body_temperature0.52890592
121MP0002136_abnormal_kidney_physiology0.51573789
122MP0005381_digestive/alimentary_phenotyp0.49447379

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)6.58104898
2Recurrent bacterial skin infections (HP:0005406)5.87822225
3Myositis (HP:0100614)4.96335856
4Vacuolated lymphocytes (HP:0001922)4.95153957
5Eczematoid dermatitis (HP:0000976)4.93611757
6Abnormality of macrophages (HP:0004311)4.69835254
7Increased neuronal autofluorescent lipopigment (HP:0002074)4.62652446
8Increased cerebral lipofuscin (HP:0011813)4.54163438
9Prolonged bleeding time (HP:0003010)4.49243658
10Recurrent gram-negative bacterial infections (HP:0005420)4.33884307
11Thrombocytosis (HP:0001894)3.95816563
12Orchitis (HP:0100796)3.87328271
13Recurrent skin infections (HP:0001581)3.79786042
14Increased mean platelet volume (HP:0011877)3.74275658
15Systemic lupus erythematosus (HP:0002725)3.71399442
16Dynein arm defect of respiratory motile cilia (HP:0012255)3.69965383
17Absent/shortened dynein arms (HP:0200106)3.69965383
18Petechiae (HP:0000967)3.57416651
19Cellulitis (HP:0100658)3.49302584
20T lymphocytopenia (HP:0005403)3.44516233
21Retrobulbar optic neuritis (HP:0100654)3.41803006
22Optic neuritis (HP:0100653)3.41803006
23Obstructive lung disease (HP:0006536)3.40176930
24Chronic obstructive pulmonary disease (HP:0006510)3.40176930
25Epistaxis (HP:0000421)3.34963260
26Gastrointestinal infarctions (HP:0005244)3.34647092
27Abnormality of T cell number (HP:0011839)3.34320815
28Spontaneous hematomas (HP:0007420)3.34053975
29Elevated erythrocyte sedimentation rate (HP:0003565)3.33275355
30Abnormal ciliary motility (HP:0012262)3.28382330
31Prostate neoplasm (HP:0100787)3.20232120
32Purpura (HP:0000979)3.19766013
33Mediastinal lymphadenopathy (HP:0100721)3.18251844
34Abnormal respiratory epithelium morphology (HP:0012253)3.17740044
35Abnormal respiratory motile cilium morphology (HP:0005938)3.17740044
36Chest pain (HP:0100749)3.16620631
37Glomerulonephritis (HP:0000099)3.07778852
38Recurrent fungal infections (HP:0002841)3.05832091
39Abnormal respiratory motile cilium physiology (HP:0012261)2.99939219
40Impaired platelet aggregation (HP:0003540)2.99837382
41Abnormal platelet function (HP:0011869)2.99837382
42Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.89622961
43IgM deficiency (HP:0002850)2.88357344
44Leukocytosis (HP:0001974)2.86586844
45Dysostosis multiplex (HP:0000943)2.86464990
46Increased IgM level (HP:0003496)2.80295027
47Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.80013098
48Menorrhagia (HP:0000132)2.77207893
49Periodontitis (HP:0000704)2.76999030
50Gingival bleeding (HP:0000225)2.76080475
51Abnormality of T cells (HP:0002843)2.75326780
52Gingivitis (HP:0000230)2.72725016
53Arterial thrombosis (HP:0004420)2.71945257
54Albinism (HP:0001022)2.71364466
55Meningitis (HP:0001287)2.69103360
56Disinhibition (HP:0000734)2.65362017
57Autoimmune hemolytic anemia (HP:0001890)2.64431258
58Interstitial pulmonary disease (HP:0006530)2.55317474
59Abnormal delayed hypersensitivity skin test (HP:0002963)2.55028422
60Loss of speech (HP:0002371)2.53625978
61Recurrent viral infections (HP:0004429)2.50470655
62Vasculitis (HP:0002633)2.49484626
63Abnormality of the prostate (HP:0008775)2.49289134
64Nasal polyposis (HP:0100582)2.48678297
65Chronic otitis media (HP:0000389)2.46340827
66Recurrent cutaneous fungal infections (HP:0011370)2.45362003
67Chronic mucocutaneous candidiasis (HP:0002728)2.45362003
68Granulocytopenia (HP:0001913)2.44757145
69Episodic fever (HP:0001954)2.43663001
70Pustule (HP:0200039)2.42946201
71Vertebral compression fractures (HP:0002953)2.42587410
72Recurrent sinusitis (HP:0011108)2.40658285
73Bronchiectasis (HP:0002110)2.39358750
74Spinal cord lesions (HP:0100561)2.39145363
75Syringomyelia (HP:0003396)2.39145363
76Recurrent bronchitis (HP:0002837)2.39008870
77Gangrene (HP:0100758)2.38699141
78Bruising susceptibility (HP:0000978)2.37752121
79Rhinitis (HP:0012384)2.37383084
80Joint hemorrhage (HP:0005261)2.37218281
81Eosinophilia (HP:0001880)2.34273257
82Increased IgE level (HP:0003212)2.33087612
83Axonal loss (HP:0003447)2.32716349
84Autoimmune thrombocytopenia (HP:0001973)2.28860631
85Stomatitis (HP:0010280)2.28196279
86Inflammation of the large intestine (HP:0002037)2.28017535
87Hematochezia (HP:0002573)2.27959213
88Absent rod-and cone-mediated responses on ERG (HP:0007688)2.26187745
89Joint swelling (HP:0001386)2.25611500
90Anorexia (HP:0002039)2.25271507
91Osteomyelitis (HP:0002754)2.24113493
92Vertigo (HP:0002321)2.24107594
93Urinary glycosaminoglycan excretion (HP:0003541)2.21357560
94Mucopolysacchariduria (HP:0008155)2.21357560
95Amyloidosis (HP:0011034)2.20764568
96Beaking of vertebral bodies (HP:0004568)2.19836047
97Hypochromic microcytic anemia (HP:0004840)2.18484672
98Urticaria (HP:0001025)2.18377993
99Chronic sinusitis (HP:0011109)2.18143064
100Peritonitis (HP:0002586)2.15518301
101Abnormal platelet volume (HP:0011876)2.14533992
102Nonprogressive disorder (HP:0003680)2.14483366
103Hyperlipoproteinemia (HP:0010980)2.13816965
104Gastrointestinal inflammation (HP:0004386)2.12303981
105Abnormality of T cell physiology (HP:0011840)2.11648865
106Colitis (HP:0002583)2.11508177
107Recurrent lower respiratory tract infections (HP:0002783)2.10810595
108Keratoconjunctivitis sicca (HP:0001097)2.10194399
109Thrombophlebitis (HP:0004418)2.10171533
110Abnormality of eosinophils (HP:0001879)2.09076057
111Abnormality of the pleura (HP:0002103)2.08965467
112Agnosia (HP:0010524)2.08746837
113Abnormality of iron homeostasis (HP:0011031)2.07955062
114Hypergammaglobulinemia (HP:0010702)2.07830744
115Nephritis (HP:0000123)2.07190683
116Agammaglobulinemia (HP:0004432)2.07098441
117Abnormality of liposaccharide metabolism (HP:0010968)2.06072440
118Abnormality of glycosphingolipid metabolism (HP:0004343)2.06072440
119Abnormality of glycolipid metabolism (HP:0010969)2.06072440
120Abnormality of the heme biosynthetic pathway (HP:0010472)2.04210809
121Bronchitis (HP:0012387)2.03862777
122Encephalitis (HP:0002383)2.03378276
123Recurrent pneumonia (HP:0006532)2.03359743
124Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.01805078
125Abnormality of polysaccharide metabolism (HP:0011012)2.01651089
126Abnormality of glycosaminoglycan metabolism (HP:0004371)2.01651089
127Abnormality of mucopolysaccharide metabolism (HP:0011020)2.01651089
128Microcytic anemia (HP:0001935)2.01319441
129Conjunctival telangiectasia (HP:0000524)2.01244684
130Hepatosplenomegaly (HP:0001433)1.99381919
131Pulmonary embolism (HP:0002204)1.99223381
132Abnormality of the nasal mucosa (HP:0000433)1.97675147
133Amaurosis fugax (HP:0100576)1.96751921
134Patchy hypopigmentation of hair (HP:0011365)1.96578486
135Osteolytic defects of the phalanges of the hand (HP:0009771)1.95721725
136Osteolytic defects of the hand bones (HP:0009699)1.95721725
137Abnormality of the vasculature of the conjunctiva (HP:0008054)1.95168592
138Basal ganglia calcification (HP:0002135)1.92338432
139Spondylolisthesis (HP:0003302)1.91664506
140Panhypogammaglobulinemia (HP:0003139)1.91301316
141Hemoptysis (HP:0002105)1.88808158
142Gastrointestinal stroma tumor (HP:0100723)1.88450435
143Keratoconjunctivitis (HP:0001096)1.85688669
144Pulmonary infiltrates (HP:0002113)1.84692726
145Abnormality of the lumbar spine (HP:0100712)1.84281079

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TGFBR23.27078048
2RIPK43.24401803
3IRAK43.11911600
4KIT3.01439999
5TIE12.88800375
6MUSK2.80460630
7BLK2.59967476
8MAP3K142.55182335
9MAP4K12.49387404
10GRK62.36038191
11TBK12.31761781
12BTK2.19615985
13TXK2.17720128
14TEC2.17571273
15NME22.07285184
16TGFBR12.04480042
17IKBKE1.97502327
18MAP3K121.94800614
19MAP3K131.89947166
20TYK21.89721884
21IKBKB1.84312874
22PIM21.82703697
23MAP2K31.75793985
24JAK31.73747924
25IRAK31.73515476
26GRK71.71433278
27MATK1.69011166
28ITK1.68750426
29FES1.62581267
30ZAP701.53785624
31CSF1R1.52797302
32TRPM71.50726367
33FRK1.50029529
34HCK1.38277784
35SYK1.36303370
36ADRBK21.33017857
37PTK2B1.32120750
38LYN1.32109055
39MAPKAPK51.20371290
40MYLK1.17912684
41ERN11.14799331
42CDK191.14625747
43LCK1.14143151
44TAOK31.11741545
45CLK11.06427664
46MKNK11.06047598
47TNIK1.02602278
48PIM11.00645576
49NEK91.00413014
50CAMKK20.99774034
51MARK30.99251856
52MOS0.98682266
53CSK0.95996924
54EPHB10.90900592
55TNK20.90701458
56PDK10.87894935
57PRPF4B0.87882519
58JAK10.85710083
59PAK40.85306602
60PRKCQ0.84970716
61PRKG20.84544962
62CHUK0.79962803
63YES10.78066238
64TLK10.77759249
65SIK30.76321232
66EIF2AK20.74676297
67GRK50.74243671
68STK100.74125238
69MAP3K20.73960247
70CDK80.73272345
71BMPR1B0.72199978
72MAP3K50.69480591
73LRRK20.68267989
74BMX0.67134007
75PBK0.66766832
76EEF2K0.66019834
77FLT30.65689799
78KDR0.65377287
79MAP3K10.64770985
80MAP3K60.64597817
81RIPK10.61873670
82FGR0.61702104
83PIK3CG0.61115959
84ACVR1B0.61048901
85PDPK10.60898383
86CAMK1D0.60704677
87PIK3CA0.60357024
88JAK20.59854202
89PRKCD0.58852180
90MAPK120.57635723
91NUAK10.56868161
92MAP2K60.56601789
93ABL10.56601659
94STK240.55458152
95MAP3K70.55339099
96NLK0.55141228
97ADRBK10.54170134
98TAOK10.54009622
99FGFR30.53071561
100IRAK10.53066731
101MAPK150.52994516
102MAPK70.52698713
103MARK20.51348736
104RPS6KA60.50857561
105GRK10.49518924
106EPHA30.49008318
107IRAK20.48386134
108ARAF0.46460863
109MST1R0.46211396
110IGF1R0.43588233
111RPS6KA50.42520818
112BCKDK0.42064603
113PKN20.41749308
114ERBB20.41728614
115TAOK20.41589776
116RPS6KB20.41298775
117MAP3K30.39521127
118BMPR20.39411961
119ILK0.39199520
120RPS6KA40.38427838
121EGFR0.37165473
122DAPK20.36853283
123OXSR10.36683376
124ABL20.36653840
125HIPK20.36610558
126FYN0.36418896
127STK40.36316577
128RET0.36284919
129SGK20.36176368
130PRKD10.35884190
131CAMK10.34878059
132SIK20.32981432
133MST40.32928059
134ERBB30.32314388
135MAP3K110.32280999
136CAMKK10.30904743
137TESK20.30839262
138TTN0.30551344
139RAF10.29748706
140MAPK40.29410580

Predicted pathways (KEGG)

RankGene SetZ-score
1Leishmaniasis_Homo sapiens_hsa051403.14506455
2Staphylococcus aureus infection_Homo sapiens_hsa051503.11547238
3Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.44033143
4Other glycan degradation_Homo sapiens_hsa005112.41851953
5Toll-like receptor signaling pathway_Homo sapiens_hsa046202.37078357
6Pertussis_Homo sapiens_hsa051332.35331743
7Malaria_Homo sapiens_hsa051442.23050292
8Osteoclast differentiation_Homo sapiens_hsa043802.22791153
9Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.16129151
10Legionellosis_Homo sapiens_hsa051342.10802878
11RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.05090532
12NF-kappa B signaling pathway_Homo sapiens_hsa040642.03962988
13Rheumatoid arthritis_Homo sapiens_hsa053232.01453241
14Lysosome_Homo sapiens_hsa041421.93446825
15Measles_Homo sapiens_hsa051621.91899521
16Tuberculosis_Homo sapiens_hsa051521.90440188
17Glycosaminoglycan degradation_Homo sapiens_hsa005311.88670289
18Hematopoietic cell lineage_Homo sapiens_hsa046401.88212744
19Ribosome_Homo sapiens_hsa030101.82395940
20Salmonella infection_Homo sapiens_hsa051321.77763237
21NOD-like receptor signaling pathway_Homo sapiens_hsa046211.76747446
22Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.75234935
23B cell receptor signaling pathway_Homo sapiens_hsa046621.74788610
24Platelet activation_Homo sapiens_hsa046111.74738863
25Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.69769916
26Shigellosis_Homo sapiens_hsa051311.69419766
27Jak-STAT signaling pathway_Homo sapiens_hsa046301.60864941
28Intestinal immune network for IgA production_Homo sapiens_hsa046721.55270912
29Phagosome_Homo sapiens_hsa041451.52415034
30SNARE interactions in vesicular transport_Homo sapiens_hsa041301.46450132
31Graft-versus-host disease_Homo sapiens_hsa053321.46247267
32Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.44430763
33Asthma_Homo sapiens_hsa053101.42000910
34Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.39244040
35Allograft rejection_Homo sapiens_hsa053301.34201969
36TNF signaling pathway_Homo sapiens_hsa046681.33882652
37Influenza A_Homo sapiens_hsa051641.31783324
38Toxoplasmosis_Homo sapiens_hsa051451.29646971
39Herpes simplex infection_Homo sapiens_hsa051681.28204601
40Chemokine signaling pathway_Homo sapiens_hsa040621.28029846
41Leukocyte transendothelial migration_Homo sapiens_hsa046701.21766414
42Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.20145156
43Antigen processing and presentation_Homo sapiens_hsa046121.19528342
44Transcriptional misregulation in cancer_Homo sapiens_hsa052021.14543337
45Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.13172911
46Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.12423259
47Apoptosis_Homo sapiens_hsa042101.11218404
48Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.08976945
49AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.07901171
50African trypanosomiasis_Homo sapiens_hsa051431.07743086
51Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.06520240
52Complement and coagulation cascades_Homo sapiens_hsa046101.04256266
53Primary immunodeficiency_Homo sapiens_hsa053401.04118797
54Caffeine metabolism_Homo sapiens_hsa002321.02160151
55Hepatitis B_Homo sapiens_hsa051611.00756970
56Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.99387922
57Acute myeloid leukemia_Homo sapiens_hsa052210.90363199
58Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.87850560
59Systemic lupus erythematosus_Homo sapiens_hsa053220.87102294
60Hepatitis C_Homo sapiens_hsa051600.86577233
61Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.86093756
62Sphingolipid metabolism_Homo sapiens_hsa006000.85756436
63Arachidonic acid metabolism_Homo sapiens_hsa005900.84412231
64Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.79887888
65Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.78439671
66Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.75200854
67Amoebiasis_Homo sapiens_hsa051460.71969092
68Non-small cell lung cancer_Homo sapiens_hsa052230.71720705
69Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.66317853
70Pentose and glucuronate interconversions_Homo sapiens_hsa000400.62093854
71Protein export_Homo sapiens_hsa030600.61358261
72Prolactin signaling pathway_Homo sapiens_hsa049170.60325808
73Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.59565841
74alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.59279234
75Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.58953357
76Chronic myeloid leukemia_Homo sapiens_hsa052200.58884144
77Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.54739229
78Autoimmune thyroid disease_Homo sapiens_hsa053200.53706010
79Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.53207929
80Sphingolipid signaling pathway_Homo sapiens_hsa040710.50823071
81Phosphatidylinositol signaling system_Homo sapiens_hsa040700.50104982
82Phospholipase D signaling pathway_Homo sapiens_hsa040720.50067054
83Dorso-ventral axis formation_Homo sapiens_hsa043200.48515141
84Type I diabetes mellitus_Homo sapiens_hsa049400.47974781
85Linoleic acid metabolism_Homo sapiens_hsa005910.47820080
86Carbohydrate digestion and absorption_Homo sapiens_hsa049730.47425543
87Vascular smooth muscle contraction_Homo sapiens_hsa042700.47379836
88Neurotrophin signaling pathway_Homo sapiens_hsa047220.46951573
89HIF-1 signaling pathway_Homo sapiens_hsa040660.46374277
90Choline metabolism in cancer_Homo sapiens_hsa052310.44575353
91ECM-receptor interaction_Homo sapiens_hsa045120.44106561
92Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.43503596
93Galactose metabolism_Homo sapiens_hsa000520.42852803
94VEGF signaling pathway_Homo sapiens_hsa043700.41975129
95Collecting duct acid secretion_Homo sapiens_hsa049660.41887324
96Pancreatic cancer_Homo sapiens_hsa052120.41863582
97Viral myocarditis_Homo sapiens_hsa054160.40827454
98Regulation of actin cytoskeleton_Homo sapiens_hsa048100.40479928
99Olfactory transduction_Homo sapiens_hsa047400.39743149
100N-Glycan biosynthesis_Homo sapiens_hsa005100.39662127
101Viral carcinogenesis_Homo sapiens_hsa052030.39647720
102Serotonergic synapse_Homo sapiens_hsa047260.39012529
103Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.37289341
104Glycerophospholipid metabolism_Homo sapiens_hsa005640.36643971
105Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.34076082
106T cell receptor signaling pathway_Homo sapiens_hsa046600.33454863
107HTLV-I infection_Homo sapiens_hsa051660.32083553
108Proteoglycans in cancer_Homo sapiens_hsa052050.31831650
109MAPK signaling pathway_Homo sapiens_hsa040100.31646598
110FoxO signaling pathway_Homo sapiens_hsa040680.31429441
111Renal cell carcinoma_Homo sapiens_hsa052110.31395267
112Prion diseases_Homo sapiens_hsa050200.31226100
113Focal adhesion_Homo sapiens_hsa045100.31225950
114Pancreatic secretion_Homo sapiens_hsa049720.30972031
115Ras signaling pathway_Homo sapiens_hsa040140.29973073
116Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.29300396
117GnRH signaling pathway_Homo sapiens_hsa049120.28623718
118Nitrogen metabolism_Homo sapiens_hsa009100.28601378
119PI3K-Akt signaling pathway_Homo sapiens_hsa041510.28082893
120Cholinergic synapse_Homo sapiens_hsa047250.27332101
121Endocytosis_Homo sapiens_hsa041440.25557488
122Regulation of autophagy_Homo sapiens_hsa041400.24905221
123Rap1 signaling pathway_Homo sapiens_hsa040150.23258461
124Epstein-Barr virus infection_Homo sapiens_hsa051690.20440501
125Adipocytokine signaling pathway_Homo sapiens_hsa049200.20034761
126Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.19963967
127Ovarian steroidogenesis_Homo sapiens_hsa049130.16934160
128p53 signaling pathway_Homo sapiens_hsa041150.16605256

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