HARBI1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1response to pheromone (GO:0019236)5.86229897
2DNA deamination (GO:0045006)4.80433177
3proteasome assembly (GO:0043248)4.25741179
4water-soluble vitamin biosynthetic process (GO:0042364)4.03862261
5tRNA methylation (GO:0030488)3.92317310
6platelet dense granule organization (GO:0060155)3.84236478
7rRNA catabolic process (GO:0016075)3.83036270
8kinetochore assembly (GO:0051382)3.80407432
9ribosomal small subunit assembly (GO:0000028)3.75366251
10cytidine metabolic process (GO:0046087)3.72828283
11cytidine catabolic process (GO:0006216)3.72828283
12cytidine deamination (GO:0009972)3.72828283
13telomere maintenance via semi-conservative replication (GO:0032201)3.63982043
14regulation of mitochondrial translation (GO:0070129)3.62244581
15termination of RNA polymerase III transcription (GO:0006386)3.61632544
16transcription elongation from RNA polymerase III promoter (GO:0006385)3.61632544
17regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.59064300
18CENP-A containing nucleosome assembly (GO:0034080)3.55116384
19rRNA modification (GO:0000154)3.53185676
20polyketide metabolic process (GO:0030638)3.52888715
21doxorubicin metabolic process (GO:0044598)3.52888715
22daunorubicin metabolic process (GO:0044597)3.52888715
23RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.52400818
24mitochondrial respiratory chain complex assembly (GO:0033108)3.50001317
25telomere maintenance via recombination (GO:0000722)3.46607965
26protein K6-linked ubiquitination (GO:0085020)3.45157487
27kinetochore organization (GO:0051383)3.44500451
28viral mRNA export from host cell nucleus (GO:0046784)3.43650713
297-methylguanosine mRNA capping (GO:0006370)3.41073720
30behavioral response to nicotine (GO:0035095)3.38311243
317-methylguanosine RNA capping (GO:0009452)3.37893064
32RNA capping (GO:0036260)3.37893064
33chromatin remodeling at centromere (GO:0031055)3.36139994
34DNA catabolic process, exonucleolytic (GO:0000738)3.33325140
35preassembly of GPI anchor in ER membrane (GO:0016254)3.32591400
36detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.30694970
37deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.28812766
38protein neddylation (GO:0045116)3.27788535
39respiratory chain complex IV assembly (GO:0008535)3.27779798
40cullin deneddylation (GO:0010388)3.25221892
41protein deneddylation (GO:0000338)3.22761082
42negative regulation of telomere maintenance (GO:0032205)3.22236460
43regulation of nuclear cell cycle DNA replication (GO:0033262)3.22134651
44replication fork processing (GO:0031297)3.18775449
45ubiquinone biosynthetic process (GO:0006744)3.17957397
46DNA replication checkpoint (GO:0000076)3.16858252
47piRNA metabolic process (GO:0034587)3.15966899
48DNA-dependent DNA replication (GO:0006261)3.13664166
49regulation of double-strand break repair via homologous recombination (GO:0010569)3.13028268
50RNA methylation (GO:0001510)3.12857593
51telomere maintenance via telomere lengthening (GO:0010833)3.12724122
52deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.12189958
53rRNA methylation (GO:0031167)3.12122658
54tRNA modification (GO:0006400)3.11886556
55DNA ligation (GO:0006266)3.11770866
56maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.11173435
57negative regulation of mast cell activation (GO:0033004)3.08929712
58DNA integration (GO:0015074)3.06766269
59DNA strand elongation involved in DNA replication (GO:0006271)3.06040059
60pyrimidine ribonucleoside catabolic process (GO:0046133)3.04389121
61mitotic recombination (GO:0006312)3.03833671
62mitotic metaphase plate congression (GO:0007080)3.02182910
63transcription from RNA polymerase I promoter (GO:0006360)3.01213923
64DNA strand elongation (GO:0022616)3.00445626
65pseudouridine synthesis (GO:0001522)2.99681182
66nucleobase biosynthetic process (GO:0046112)2.99575213
67termination of RNA polymerase I transcription (GO:0006363)2.99451363
68DNA replication initiation (GO:0006270)2.98285633
69maturation of 5.8S rRNA (GO:0000460)2.98247471
70cytochrome complex assembly (GO:0017004)2.97587043
71mannosylation (GO:0097502)2.97155716
72single strand break repair (GO:0000012)2.97138564
73DNA synthesis involved in DNA repair (GO:0000731)2.96893323
74tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.95721776
75RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.95721776
76DNA damage response, detection of DNA damage (GO:0042769)2.94802661
77ribosomal large subunit biogenesis (GO:0042273)2.94446902
78ribosome biogenesis (GO:0042254)2.93156857
79spliceosomal snRNP assembly (GO:0000387)2.92621006
80regulation of cellular amino acid metabolic process (GO:0006521)2.92224316
81ubiquinone metabolic process (GO:0006743)2.91470967
82exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.91329881
83transcription elongation from RNA polymerase I promoter (GO:0006362)2.90848886
84nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.90826203
85indolalkylamine metabolic process (GO:0006586)2.90680593
86tRNA processing (GO:0008033)2.89836761
87axoneme assembly (GO:0035082)2.89772676
88purine nucleobase biosynthetic process (GO:0009113)2.89497604
89microtubule depolymerization (GO:0007019)2.87935062
90mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.86709172
91L-fucose catabolic process (GO:0042355)2.86468295
92fucose catabolic process (GO:0019317)2.86468295
93L-fucose metabolic process (GO:0042354)2.86468295
94deoxyribonucleotide biosynthetic process (GO:0009263)2.85849212
95negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.85754437
96transcription-coupled nucleotide-excision repair (GO:0006283)2.83304988
97somatic hypermutation of immunoglobulin genes (GO:0016446)2.83115446
98somatic diversification of immune receptors via somatic mutation (GO:0002566)2.83115446
99regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.82447471
100interferon-gamma production (GO:0032609)2.82235248
101establishment of protein localization to mitochondrial membrane (GO:0090151)2.80929164
102L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.80005515
103GPI anchor metabolic process (GO:0006505)2.78627788
104metaphase plate congression (GO:0051310)2.78531585
105indole-containing compound catabolic process (GO:0042436)2.78293180
106indolalkylamine catabolic process (GO:0046218)2.78293180
107tryptophan catabolic process (GO:0006569)2.78293180
108ATP synthesis coupled proton transport (GO:0015986)2.77617914
109energy coupled proton transport, down electrochemical gradient (GO:0015985)2.77617914
110protein complex biogenesis (GO:0070271)2.77477516
111regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.76606912
112pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.75387455
113DNA double-strand break processing (GO:0000729)2.75288350
114base-excision repair, AP site formation (GO:0006285)2.75208108
115ribonucleoprotein complex biogenesis (GO:0022613)2.74430758
116epithelial cilium movement (GO:0003351)2.74334520
117positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.73677352
118nucleotide-excision repair, DNA gap filling (GO:0006297)2.73423298
119mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.72619396
120mitochondrial respiratory chain complex I assembly (GO:0032981)2.72619396
121NADH dehydrogenase complex assembly (GO:0010257)2.72619396
122signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.70634083
123signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.70634083
124signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.70634083
125mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.70086501
126maturation of SSU-rRNA (GO:0030490)2.69081697
127intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.67721217
128signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.67721217
129regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.66809687
130regulation of mitotic spindle checkpoint (GO:1903504)2.66809687
131positive regulation of prostaglandin secretion (GO:0032308)2.65846172
132protein-cofactor linkage (GO:0018065)2.65537285
133centriole assembly (GO:0098534)2.65036795
134cornea development in camera-type eye (GO:0061303)2.64720987
135purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)2.64307930
136meiotic chromosome segregation (GO:0045132)2.63697057
137metallo-sulfur cluster assembly (GO:0031163)2.63569989
138iron-sulfur cluster assembly (GO:0016226)2.63569989
139detection of light stimulus involved in sensory perception (GO:0050962)2.63086356
140detection of light stimulus involved in visual perception (GO:0050908)2.63086356
141DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.62282957
142deoxyribonucleotide catabolic process (GO:0009264)2.62018031
143anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.61720760
144signal transduction involved in cell cycle checkpoint (GO:0072395)2.61293006
145tRNA metabolic process (GO:0006399)2.61094791
146histone exchange (GO:0043486)2.61039449
147regulation of helicase activity (GO:0051095)2.60784615
148cellular component biogenesis (GO:0044085)2.60085316
149pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.59644325
150transcription elongation from RNA polymerase II promoter (GO:0006368)2.59074634
151RNA-dependent DNA replication (GO:0006278)2.58979401
152GPI anchor biosynthetic process (GO:0006506)2.56455532
153protein K11-linked deubiquitination (GO:0035871)2.56093352
154signal transduction involved in DNA integrity checkpoint (GO:0072401)2.54182869
155signal transduction involved in DNA damage checkpoint (GO:0072422)2.54182869
156cilium morphogenesis (GO:0060271)2.53932572
157male meiosis I (GO:0007141)2.53762756
158C-terminal protein lipidation (GO:0006501)2.51595275
159epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.51511500
160amino acid salvage (GO:0043102)2.50566658
161L-methionine salvage (GO:0071267)2.50566658
162L-methionine biosynthetic process (GO:0071265)2.50566658
163quinone biosynthetic process (GO:1901663)2.48363718
164endoderm formation (GO:0001706)2.45945673
165cellular ketone body metabolic process (GO:0046950)2.45783968
166male meiosis (GO:0007140)2.45754930
167isotype switching (GO:0045190)2.44678500

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.90091837
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.48046173
3ELF1_17652178_ChIP-ChIP_JURKAT_Human3.66237974
4GABP_17652178_ChIP-ChIP_JURKAT_Human3.64335681
5* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.61177633
6HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.53578642
7ZNF274_21170338_ChIP-Seq_K562_Hela3.52598758
8EST1_17652178_ChIP-ChIP_JURKAT_Human3.52224238
9MYC_18555785_ChIP-Seq_MESCs_Mouse3.16944465
10NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.06615138
11E2F4_17652178_ChIP-ChIP_JURKAT_Human2.84214855
12HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.77559247
13VDR_22108803_ChIP-Seq_LS180_Human2.71115776
14ETS1_20019798_ChIP-Seq_JURKAT_Human2.69513720
15SRF_21415370_ChIP-Seq_HL-1_Mouse2.48640814
16CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.46900502
17* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.46552641
18VDR_23849224_ChIP-Seq_CD4+_Human2.45667261
19MYC_18358816_ChIP-ChIP_MESCs_Mouse2.41109902
20HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.39053166
21CREB1_15753290_ChIP-ChIP_HEK293T_Human2.35185265
22MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.33020233
23E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.31660886
24CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.31114982
25MYC_19030024_ChIP-ChIP_MESCs_Mouse2.27973937
26NOTCH1_21737748_ChIP-Seq_TLL_Human2.23745823
27* FOXP3_21729870_ChIP-Seq_TREG_Human2.22829757
28POU3F2_20337985_ChIP-ChIP_501MEL_Human2.20690315
29IGF1R_20145208_ChIP-Seq_DFB_Human2.19531506
30ELK1_19687146_ChIP-ChIP_HELA_Human2.18704872
31GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.15879442
32FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.09589789
33HOXB4_20404135_ChIP-ChIP_EML_Mouse1.98219953
34YY1_21170310_ChIP-Seq_MESCs_Mouse1.97314729
35DCP1A_22483619_ChIP-Seq_HELA_Human1.94367066
36MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.93644882
37PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.90776789
38GBX2_23144817_ChIP-Seq_PC3_Human1.87975431
39SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.86262545
40* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.85524915
41IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.84978687
42E2F1_18555785_ChIP-Seq_MESCs_Mouse1.84346161
43YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.76895042
44MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.76497742
45EGR1_23403033_ChIP-Seq_LIVER_Mouse1.75969204
46MYC_19079543_ChIP-ChIP_MESCs_Mouse1.75440158
47NELFA_20434984_ChIP-Seq_ESCs_Mouse1.74760896
48P300_19829295_ChIP-Seq_ESCs_Human1.73493611
49CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.70760369
50PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.69042027
51FUS_26573619_Chip-Seq_HEK293_Human1.67260711
52CTBP1_25329375_ChIP-Seq_LNCAP_Human1.66299827
53ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.64193777
54TP63_19390658_ChIP-ChIP_HaCaT_Human1.62804611
55CTBP2_25329375_ChIP-Seq_LNCAP_Human1.56970075
56TP53_22573176_ChIP-Seq_HFKS_Human1.55732442
57FLI1_27457419_Chip-Seq_LIVER_Mouse1.55700749
58EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.54727770
59PCGF2_27294783_Chip-Seq_ESCs_Mouse1.54544952
60PADI4_21655091_ChIP-ChIP_MCF-7_Human1.52264235
61ER_23166858_ChIP-Seq_MCF-7_Human1.52195911
62TAF15_26573619_Chip-Seq_HEK293_Human1.51786112
63TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.51560839
64THAP11_20581084_ChIP-Seq_MESCs_Mouse1.50791723
65IRF1_19129219_ChIP-ChIP_H3396_Human1.50751493
66GABP_19822575_ChIP-Seq_HepG2_Human1.50364730
67EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.49245662
68ERG_20887958_ChIP-Seq_HPC-7_Mouse1.48462334
69MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.47778769
70CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.45745325
71SALL1_21062744_ChIP-ChIP_HESCs_Human1.45441573
72FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.44401146
73TTF2_22483619_ChIP-Seq_HELA_Human1.43459680
74FOXA1_25329375_ChIP-Seq_VCAP_Human1.42597260
75FOXA1_27270436_Chip-Seq_PROSTATE_Human1.42597260
76SOX2_19829295_ChIP-Seq_ESCs_Human1.41484271
77NANOG_19829295_ChIP-Seq_ESCs_Human1.41484271
78XRN2_22483619_ChIP-Seq_HELA_Human1.40946028
79AR_20517297_ChIP-Seq_VCAP_Human1.38218603
80E2F1_21310950_ChIP-Seq_MCF-7_Human1.37781676
81SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.37333821
82SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.36290193
83CBP_20019798_ChIP-Seq_JUKART_Human1.36150161
84IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.36150161
85* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.35799039
86* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.35015607
87NANOG_18555785_ChIP-Seq_MESCs_Mouse1.31449230
88CIITA_25753668_ChIP-Seq_RAJI_Human1.30824050
89GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.29793834
90POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.28611870
91GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.28284321
92GATA3_26560356_Chip-Seq_TH2_Human1.26930699
93MYCN_18555785_ChIP-Seq_MESCs_Mouse1.26784791
94KAP1_22055183_ChIP-Seq_ESCs_Mouse1.26594448
95CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.25251193
96* EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.23481720
97TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.22931014
98UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.22816236
99FOXA1_21572438_ChIP-Seq_LNCaP_Human1.22672791
100IRF8_21731497_ChIP-ChIP_J774_Mouse1.22113519
101CRX_20693478_ChIP-Seq_RETINA_Mouse1.21359158
102NFE2_27457419_Chip-Seq_LIVER_Mouse1.18360997
103FOXM1_23109430_ChIP-Seq_U2OS_Human1.17306075
104MYC_18940864_ChIP-ChIP_HL60_Human1.16944115
105POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.16681415
106SUZ12_27294783_Chip-Seq_NPCs_Mouse1.15669586
107BCAT_22108803_ChIP-Seq_LS180_Human1.14600611
108KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.09213611
109PCGF2_27294783_Chip-Seq_NPCs_Mouse1.07809490
110AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.05703732
111KLF5_20875108_ChIP-Seq_MESCs_Mouse1.05314060
112CDX2_22108803_ChIP-Seq_LS180_Human1.04980634
113NCOR_22424771_ChIP-Seq_293T_Human1.04754691
114PHF8_20622853_ChIP-Seq_HELA_Human1.04067478
115TCF4_22108803_ChIP-Seq_LS180_Human1.03568972
116SOX2_18555785_ChIP-Seq_MESCs_Mouse1.02121378
117RBPJ_21746931_ChIP-Seq_IB4_Human1.02089105
118GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.01972305
119FOXH1_21741376_ChIP-Seq_EPCs_Human1.01257171
120HOXB7_26014856_ChIP-Seq_BT474_Human1.00674457
121GATA3_21878914_ChIP-Seq_MCF-7_Human1.00607172
122MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.00053285
123CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.99913854
124PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.99492089
125AR_25329375_ChIP-Seq_VCAP_Human0.98670852
126SMAD4_21799915_ChIP-Seq_A2780_Human0.97284818
127SMAD4_21741376_ChIP-Seq_EPCs_Human0.96614274
128PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.95895502
129LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.95564112
130SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.95540079
131CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.95471200
132NANOG_20526341_ChIP-Seq_ESCs_Human0.95361820
133GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.95322828
134CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.94591617
135EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.94352326
136P53_22387025_ChIP-Seq_ESCs_Mouse0.93828193
137ZFP57_27257070_Chip-Seq_ESCs_Mouse0.93366964
138NANOG_18555785_Chip-Seq_ESCs_Mouse0.92887528
139* SPI1_23547873_ChIP-Seq_NB4_Human0.92328305
140EZH2_27294783_Chip-Seq_NPCs_Mouse0.87496297
141BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.87473557
142RBPJ_22232070_ChIP-Seq_NCS_Mouse0.87420225
143POU5F1_16153702_ChIP-ChIP_HESCs_Human0.87060042
144IRF8_22096565_ChIP-ChIP_GC-B_Human0.85220694
145NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.85090227
146STAT3_18555785_Chip-Seq_ESCs_Mouse0.84461868
147STAT4_19710469_ChIP-ChIP_TH1__Mouse0.81076754
148EWS_26573619_Chip-Seq_HEK293_Human0.80599883
149MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.79030448
150* RUNX1_27457419_Chip-Seq_LIVER_Mouse0.77751064
151ELK1_22589737_ChIP-Seq_MCF10A_Human0.77224007
152SCL_19346495_ChIP-Seq_HPC-7_Human0.76526585
153ZFX_18555785_Chip-Seq_ESCs_Mouse0.75473999
154DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.75180644
155CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.74713133
156NMYC_18555785_Chip-Seq_ESCs_Mouse0.73677562

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching3.99195779
2MP0008058_abnormal_DNA_repair3.58431578
3MP0006292_abnormal_olfactory_placode3.22458111
4MP0001188_hyperpigmentation2.99471022
5MP0001986_abnormal_taste_sensitivity2.99375481
6MP0008057_abnormal_DNA_replication2.89657007
7MP0010094_abnormal_chromosome_stability2.64861910
8MP0006072_abnormal_retinal_apoptosis2.57313649
9MP0005551_abnormal_eye_electrophysiolog2.35717813
10MP0002132_abnormal_respiratory_system2.35494186
11MP0003111_abnormal_nucleus_morphology2.32591506
12MP0009697_abnormal_copulation2.31004486
13MP0000566_synostosis2.25767919
14MP0005075_abnormal_melanosome_morpholog2.16783401
15MP0008875_abnormal_xenobiotic_pharmacok2.10176406
16MP0002837_dystrophic_cardiac_calcinosis2.08992974
17MP0003786_premature_aging2.08556605
18MP0003077_abnormal_cell_cycle2.07616583
19MP0005253_abnormal_eye_physiology2.05236231
20MP0008877_abnormal_DNA_methylation2.02121923
21MP0002653_abnormal_ependyma_morphology1.96763097
22MP0008007_abnormal_cellular_replicative1.95979831
23MP0008872_abnormal_physiological_respon1.93647497
24MP0001764_abnormal_homeostasis1.92666849
25MP0005084_abnormal_gallbladder_morpholo1.89831601
26MP0002396_abnormal_hematopoietic_system1.87662410
27MP0004147_increased_porphyrin_level1.85065235
28MP0000015_abnormal_ear_pigmentation1.79185561
29MP0001853_heart_inflammation1.77240721
30MP0002638_abnormal_pupillary_reflex1.74872303
31MP0005174_abnormal_tail_pigmentation1.72809207
32MP0002277_abnormal_respiratory_mucosa1.71055806
33MP0003718_maternal_effect1.68555974
34MP0004142_abnormal_muscle_tone1.67404263
35MP0001835_abnormal_antigen_presentation1.65393068
36MP0003646_muscle_fatigue1.60940281
37MP0003763_abnormal_thymus_physiology1.60835317
38MP0004381_abnormal_hair_follicle1.60317748
39MP0009379_abnormal_foot_pigmentation1.59765701
40MP0009785_altered_susceptibility_to1.59092746
41MP0005360_urolithiasis1.57386064
42MP0001984_abnormal_olfaction1.55072884
43MP0005671_abnormal_response_to1.53713809
44MP0004957_abnormal_blastocyst_morpholog1.50514472
45MP0002876_abnormal_thyroid_physiology1.50262444
46MP0005171_absent_coat_pigmentation1.49195005
47MP0002736_abnormal_nociception_after1.48903978
48MP0002102_abnormal_ear_morphology1.48293046
49MP0003950_abnormal_plasma_membrane1.47482604
50MP0001968_abnormal_touch/_nociception1.47367968
51MP0004782_abnormal_surfactant_physiolog1.46551625
52MP0008995_early_reproductive_senescence1.43734258
53MP0000569_abnormal_digit_pigmentation1.39032308
54MP0002160_abnormal_reproductive_system1.37303434
55MP0005410_abnormal_fertilization1.36091549
56MP0005389_reproductive_system_phenotype1.35016119
57MP0000372_irregular_coat_pigmentation1.34892118
58MP0003880_abnormal_central_pattern1.34609196
59MP0002148_abnormal_hypersensitivity_rea1.34505277
60MP0005379_endocrine/exocrine_gland_phen1.33083204
61MP0003186_abnormal_redox_activity1.32594094
62MP0003941_abnormal_skin_development1.32115991
63MP0000681_abnormal_thyroid_gland1.31868576
64MP0002163_abnormal_gland_morphology1.31455052
65MP0002095_abnormal_skin_pigmentation1.30734741
66MP0009333_abnormal_splenocyte_physiolog1.30386040
67MP0006082_CNS_inflammation1.26630208
68MP0001501_abnormal_sleep_pattern1.24065109
69MP0000685_abnormal_immune_system1.23861468
70MP0005409_darkened_coat_color1.23725155
71MP0002938_white_spotting1.22368353
72MP0003724_increased_susceptibility_to1.21789900
73MP0003195_calcinosis1.21462299
74MP0004742_abnormal_vestibular_system1.20696303
75MP0003787_abnormal_imprinting1.20443786
76MP0002210_abnormal_sex_determination1.19230819
77MP0003136_yellow_coat_color1.19034280
78MP0003191_abnormal_cellular_cholesterol1.18988535
79MP0002928_abnormal_bile_duct1.18891324
80MP0008932_abnormal_embryonic_tissue1.18639098
81MP0003806_abnormal_nucleotide_metabolis1.18467123
82MP0001529_abnormal_vocalization1.17469023
83MP0008260_abnormal_autophagy1.17007792
84MP0006276_abnormal_autonomic_nervous1.15851368
85MP0006036_abnormal_mitochondrial_physio1.15481219
86MP0005365_abnormal_bile_salt1.13974972
87MP0001119_abnormal_female_reproductive1.12748855
88MP0005408_hypopigmentation1.12709362
89MP0002139_abnormal_hepatobiliary_system1.12520688
90MP0002751_abnormal_autonomic_nervous1.10939076
91MP0000631_abnormal_neuroendocrine_gland1.09614684
92MP0005646_abnormal_pituitary_gland1.09064253
93MP0000678_abnormal_parathyroid_gland1.09021042
94MP0001919_abnormal_reproductive_system1.07258304
95MP0005085_abnormal_gallbladder_physiolo1.06351857
96MP0003252_abnormal_bile_duct1.05884226
97MP0000427_abnormal_hair_cycle1.05844263
98MP0001485_abnormal_pinna_reflex1.04424043
99MP0005332_abnormal_amino_acid1.03883289
100MP0001186_pigmentation_phenotype1.03816151
101MP0002138_abnormal_hepatobiliary_system1.03426661
102MP0004043_abnormal_pH_regulation1.01419173
103MP0010386_abnormal_urinary_bladder1.00657538
104MP0009745_abnormal_behavioral_response0.99927234
105MP0002272_abnormal_nervous_system0.98667891
106MP0009764_decreased_sensitivity_to0.98493811
107MP0009780_abnormal_chondrocyte_physiolo0.98152511
108MP0008789_abnormal_olfactory_epithelium0.97097759
109MP0005670_abnormal_white_adipose0.95790064
110MP0005645_abnormal_hypothalamus_physiol0.94948376
111MP0005025_abnormal_response_to0.94737455
112MP0001324_abnormal_eye_pigmentation0.93426285
113MP0004019_abnormal_vitamin_homeostasis0.93127508
114MP0000490_abnormal_crypts_of0.92137339
115MP0005367_renal/urinary_system_phenotyp0.90761482
116MP0000516_abnormal_urinary_system0.90761482
117MP0005647_abnormal_sex_gland0.87680622
118MP0009046_muscle_twitch0.86411008
119MP0002419_abnormal_innate_immunity0.86266061
120MP0005310_abnormal_salivary_gland0.85638254
121MP0001542_abnormal_bone_strength0.85548210
122MP0001145_abnormal_male_reproductive0.85341223
123MP0001800_abnormal_humoral_immune0.84831780
124MP0000613_abnormal_salivary_gland0.83810725
125MP0000653_abnormal_sex_gland0.82835552
126MP0001929_abnormal_gametogenesis0.82695006
127MP0002090_abnormal_vision0.82445782
128MP0005387_immune_system_phenotype0.81819474
129MP0001790_abnormal_immune_system0.81819474
130MP0003011_delayed_dark_adaptation0.81119750
131MP0002723_abnormal_immune_serum0.80862222
132MP0003698_abnormal_male_reproductive0.79745700
133MP0005195_abnormal_posterior_eye0.79736492
134MP0002420_abnormal_adaptive_immunity0.79518765
135MP0001819_abnormal_immune_cell0.79129053
136MP0005636_abnormal_mineral_homeostasis0.79056801
137MP0008775_abnormal_heart_ventricle0.78965609
138MP0002398_abnormal_bone_marrow0.78953526
139MP0002693_abnormal_pancreas_physiology0.78059675
140MP0001348_abnormal_lacrimal_gland0.77681735
141MP0000689_abnormal_spleen_morphology0.76983344
142MP0002075_abnormal_coat/hair_pigmentati0.76512305
143MP0005000_abnormal_immune_tolerance0.76383911
144MP0002452_abnormal_antigen_presenting0.76142927
145MP0002282_abnormal_trachea_morphology0.74970407
146MP0002234_abnormal_pharynx_morphology0.74413249
147MP0000716_abnormal_immune_system0.73173570
148MP0001905_abnormal_dopamine_level0.72168002
149MP0005391_vision/eye_phenotype0.71652254
150MP0003137_abnormal_impulse_conducting0.71497364
151MP0002429_abnormal_blood_cell0.70511545
152MP0003943_abnormal_hepatobiliary_system0.70118216
153MP0000313_abnormal_cell_death0.69868577
154MP0005395_other_phenotype0.69352537

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)4.03941594
2Chromsome breakage (HP:0040012)3.81504639
3Birth length less than 3rd percentile (HP:0003561)3.68686436
4Abnormality of midbrain morphology (HP:0002418)3.61119170
5Molar tooth sign on MRI (HP:0002419)3.61119170
6Microvesicular hepatic steatosis (HP:0001414)3.55700239
7Type I transferrin isoform profile (HP:0003642)3.37568384
8Nephronophthisis (HP:0000090)3.31411486
9Congenital stationary night blindness (HP:0007642)3.31068492
10Breast hypoplasia (HP:0003187)3.08049208
11Severe combined immunodeficiency (HP:0004430)3.03351547
12Thyroiditis (HP:0100646)2.95242050
13Abnormality of the preputium (HP:0100587)2.95068718
14Meckel diverticulum (HP:0002245)2.92225753
15Reduced antithrombin III activity (HP:0001976)2.91690645
16Acute encephalopathy (HP:0006846)2.87729656
17Abnormality of the ileum (HP:0001549)2.83963441
18Abnormality of the renal cortex (HP:0011035)2.81599428
19Abnormality of the renal medulla (HP:0100957)2.78661713
20Progressive macrocephaly (HP:0004481)2.78377029
21Abnormal biliary tract physiology (HP:0012439)2.74608168
22Bile duct proliferation (HP:0001408)2.74608168
23IgG deficiency (HP:0004315)2.74607948
24Methylmalonic acidemia (HP:0002912)2.74216457
25Abnormality of chromosome stability (HP:0003220)2.72576985
26Abnormal mitochondria in muscle tissue (HP:0008316)2.70311285
27Abnormal hair whorl (HP:0010721)2.68290804
28Abnormal rod and cone electroretinograms (HP:0008323)2.66776709
29Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.66567529
30Aplasia/Hypoplasia of the uvula (HP:0010293)2.63894421
31Methylmalonic aciduria (HP:0012120)2.62394402
32Aplastic anemia (HP:0001915)2.53340034
33Fair hair (HP:0002286)2.53254915
34Bone marrow hypocellularity (HP:0005528)2.53067269
35Abnormality of eosinophils (HP:0001879)2.51565565
36Impulsivity (HP:0100710)2.50365140
37Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.47942225
38Optic disc pallor (HP:0000543)2.46815645
39Progressive external ophthalmoplegia (HP:0000590)2.42808486
40Type II lissencephaly (HP:0007260)2.41550112
41Renal cortical cysts (HP:0000803)2.41394886
42Abolished electroretinogram (ERG) (HP:0000550)2.41272335
43Abnormal protein glycosylation (HP:0012346)2.40845634
44Abnormal glycosylation (HP:0012345)2.40845634
45Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.40845634
46Abnormal protein N-linked glycosylation (HP:0012347)2.40845634
47Renal Fanconi syndrome (HP:0001994)2.35580719
48Combined immunodeficiency (HP:0005387)2.34130714
49Chronic hepatic failure (HP:0100626)2.33498163
50Constricted visual fields (HP:0001133)2.30961215
513-Methylglutaconic aciduria (HP:0003535)2.30730178
52Keratoconus (HP:0000563)2.29605014
53Increased corneal curvature (HP:0100692)2.29605014
54Reticulocytopenia (HP:0001896)2.27834335
55Pancreatic fibrosis (HP:0100732)2.26971788
56Clubbing of toes (HP:0100760)2.26801977
57Gaze-evoked nystagmus (HP:0000640)2.20737718
58Increased serum lactate (HP:0002151)2.19075245
59Tubulointerstitial nephritis (HP:0001970)2.18829039
60Increased hepatocellular lipid droplets (HP:0006565)2.17563637
61True hermaphroditism (HP:0010459)2.13437972
62Pancreatic cysts (HP:0001737)2.12956779
63Decreased activity of mitochondrial respiratory chain (HP:0008972)2.12856410
64Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.12856410
65Sclerocornea (HP:0000647)2.12272101
66Duplicated collecting system (HP:0000081)2.12227176
67Progressive inability to walk (HP:0002505)2.12075004
68Congenital primary aphakia (HP:0007707)2.11835589
69Conjugated hyperbilirubinemia (HP:0002908)2.11300268
70Mitochondrial inheritance (HP:0001427)2.10976461
71Hypothermia (HP:0002045)2.10841067
72Severe visual impairment (HP:0001141)2.10804353
73Nephrogenic diabetes insipidus (HP:0009806)2.10733520
74Decreased electroretinogram (ERG) amplitude (HP:0000654)2.10414443
75Abnormality of pyrimidine metabolism (HP:0004353)2.10372560
76Pendular nystagmus (HP:0012043)2.10109436
77Abnormal number of erythroid precursors (HP:0012131)2.09611833
78Oral leukoplakia (HP:0002745)2.08809267
79Patellar aplasia (HP:0006443)2.08658980
80Large for gestational age (HP:0001520)2.08547444
81Abnormality of the renal collecting system (HP:0004742)2.08339458
82Aplasia cutis congenita (HP:0001057)2.07762079
83Hepatic necrosis (HP:0002605)2.07438923
84Gait imbalance (HP:0002141)2.06949711
85Eosinophilia (HP:0001880)2.06781503
86Premature graying of hair (HP:0002216)2.06263780
87Autoimmune thrombocytopenia (HP:0001973)2.06046277
88Cystic liver disease (HP:0006706)2.05750020
89Patchy hypopigmentation of hair (HP:0011365)2.04167090
90Increased CSF lactate (HP:0002490)2.02897560
91Pancytopenia (HP:0001876)2.01858829
92Aplasia/hypoplasia of the uterus (HP:0008684)2.01683508
93Aplasia/Hypoplasia of the tongue (HP:0010295)2.01041405
94Prolonged neonatal jaundice (HP:0006579)1.99637707
95Hepatocellular necrosis (HP:0001404)1.98959763
96Generalized hypopigmentation of hair (HP:0011358)1.97727945
97Granulocytopenia (HP:0001913)1.96420501
98Abnormality of the fovea (HP:0000493)1.95527056
99Abnormality of T cell number (HP:0011839)1.95066230
100Intestinal atresia (HP:0011100)1.94458799
101Dry hair (HP:0011359)1.94135130
102Abnormality of the prostate (HP:0008775)1.93049096
103Aplasia/Hypoplasia of the patella (HP:0006498)1.93029008
104Abnormal spermatogenesis (HP:0008669)1.92064059
105Abnormality of the pons (HP:0007361)1.91792491
106Abnormality of B cell number (HP:0010975)1.91552406
107Increased intramyocellular lipid droplets (HP:0012240)1.91061534
108Triphalangeal thumb (HP:0001199)1.90294687
109White forelock (HP:0002211)1.89794209
110Rough bone trabeculation (HP:0100670)1.88863610
111Abnormal albumin level (HP:0012116)1.88023158
112Hypoalbuminemia (HP:0003073)1.88023158
113Duodenal stenosis (HP:0100867)1.88000347
114Small intestinal stenosis (HP:0012848)1.88000347
115Type 2 muscle fiber atrophy (HP:0003554)1.87305874
116Proximal tubulopathy (HP:0000114)1.86881028
117Acute necrotizing encephalopathy (HP:0006965)1.86309029
118Abnormality of cells of the erythroid lineage (HP:0012130)1.85910203
119Exertional dyspnea (HP:0002875)1.85500706
120Median cleft lip (HP:0000161)1.85041837
121Cerebral edema (HP:0002181)1.84870045
122Pulmonary fibrosis (HP:0002206)1.82906303
12311 pairs of ribs (HP:0000878)1.82716055
124Myelodysplasia (HP:0002863)1.82159636
125Ketosis (HP:0001946)1.81696691
126Hypoplasia of the pons (HP:0012110)1.81531371
127Lipid accumulation in hepatocytes (HP:0006561)1.81512073
128Abnormality of macular pigmentation (HP:0008002)1.81266163
129Tubular atrophy (HP:0000092)1.80644671
130Absent rod-and cone-mediated responses on ERG (HP:0007688)1.79668348
131Supernumerary spleens (HP:0009799)1.79590165
132Lissencephaly (HP:0001339)1.79183825
133Stomatitis (HP:0010280)1.78780351
134Hyperglycinemia (HP:0002154)1.77845437
135Anencephaly (HP:0002323)1.77520307
136Septo-optic dysplasia (HP:0100842)1.76670161
137Inability to walk (HP:0002540)1.76610470
138Genital tract atresia (HP:0001827)1.74498148
139Respiratory failure (HP:0002878)1.74344636
140Generalized aminoaciduria (HP:0002909)1.74213303
141Azoospermia (HP:0000027)1.73729235
142Cheilitis (HP:0100825)1.73142684
143Abnormality of renal resorption (HP:0011038)1.72872512
144Lethargy (HP:0001254)1.72806033
145Facial cleft (HP:0002006)1.72597957
146Rectal fistula (HP:0100590)1.71540243
147Rectovaginal fistula (HP:0000143)1.71540243
148Abnormality of urine glucose concentration (HP:0011016)1.70385030
149Glycosuria (HP:0003076)1.70385030
150Abnormality of vitamin B metabolism (HP:0004340)1.70229915
151Ectopic kidney (HP:0000086)1.70105217
152Abnormality of alanine metabolism (HP:0010916)1.70100569
153Respiratory difficulties (HP:0002880)1.69550601
154Increased IgM level (HP:0003496)1.68971239
155Medial flaring of the eyebrow (HP:0010747)1.68255271
156Attenuation of retinal blood vessels (HP:0007843)1.68183767
157Hypoproteinemia (HP:0003075)1.67124957
158Optic nerve coloboma (HP:0000588)1.66116502
159Lactic acidosis (HP:0003128)1.65606231
160Retrobulbar optic neuritis (HP:0100654)1.64712317
161Optic neuritis (HP:0100653)1.64712317
162IgM deficiency (HP:0002850)1.64682667
163Sloping forehead (HP:0000340)1.64528866
164Absent thumb (HP:0009777)1.62434321
165Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.61181774
166Hyperalaninemia (HP:0003348)1.61181774

Predicted kinase interactions (KEA)

RankGene SetZ-score
1IRAK33.93056056
2STK163.81701743
3FRK3.57713264
4PLK43.32067209
5ZAK3.21506929
6IRAK42.92909207
7MAP4K22.79182732
8SRPK12.69880695
9BUB12.66791130
10TXK2.40730445
11BCR2.38882345
12TRIM282.32774839
13EIF2AK12.23486168
14VRK12.07239114
15AKT32.02152735
16VRK22.00859960
17MKNK21.91479630
18EIF2AK31.82912071
19EIF2AK21.74394178
20MST41.66195293
21EPHA21.64899676
22WEE11.62670395
23CASK1.54940558
24IRAK21.53728822
25YES11.49462965
26IRAK11.46952183
27MKNK11.46038426
28TSSK61.39998090
29TEC1.39652717
30ADRBK21.36173218
31CDK81.34305435
32TLK11.32958724
33OXSR11.29870014
34MAPK131.29845496
35NME21.28557106
36MAP3K141.27788350
37ERBB31.20356316
38STK38L1.19937286
39INSRR1.19885591
40ATR1.17957673
41NUAK11.15222856
42PAK31.14371543
43PLK21.14233726
44TNIK1.12788169
45STK391.10812557
46TTK1.08719218
47BLK1.08430888
48PBK1.06533157
49PLK11.05411205
50PINK11.03512531
51CCNB11.03337496
52WNK41.01440258
53GRK11.01119045
54IKBKB1.01081567
55ACVR1B0.99615444
56BMPR1B0.98815928
57NEK60.97375639
58PLK30.95531013
59FLT30.95501386
60CDC70.95463522
61STK30.95386639
62MAP3K120.94006340
63CDK190.93405357
64PASK0.91296875
65ITK0.91157322
66CDK70.90711885
67BMPR20.90583992
68TESK20.86660373
69NLK0.86080647
70KIT0.84829038
71BCKDK0.84646758
72CHEK20.81617062
73PIM10.79895370
74CSNK1G30.79047523
75GRK70.78739230
76MAP2K70.78686488
77NEK90.77325943
78PIM20.76955177
79BRSK20.76804527
80IKBKE0.76438237
81AURKB0.75526028
82MAP3K40.75198813
83BTK0.75013953
84BRD40.72464354
85RAF10.72382120
86CSNK1G20.71961286
87KSR10.71811052
88CSNK1G10.71445149
89STK40.69879578
90BRAF0.69528325
91MAPKAPK30.68979867
92MAP4K10.68136651
93STK240.64660284
94DYRK20.64306879
95LYN0.63987962
96PIK3CA0.62440974
97ADRBK10.62355183
98TAOK30.62320335
99GRK60.61591291
100LIMK10.61218354
101MUSK0.60968239
102PRKCE0.59730944
103CSNK2A10.59621831
104PRKCQ0.59398372
105MAPKAPK50.58598894
106SIK30.57647216
107CSNK1A1L0.57106097
108CHUK0.55276764
109KDR0.55259260
110TIE10.55129501
111CAMKK20.54066229
112SGK20.53484436
113FER0.50466237
114AURKA0.50235482
115PRKCI0.50168372
116MAP2K60.48670475
117ATM0.47966622
118SIK20.46855610
119MAPK150.46267802
120DYRK30.46204252
121PRKCG0.46060723
122TNK20.45944168
123CDK30.45686404
124DAPK10.45276076
125MARK10.44379684
126TAOK20.43730075
127NME10.43395746
128CSNK2A20.42428021
129IGF1R0.41769650
130CHEK10.41484385
131PDK20.41347566
132TRPM70.39155425
133TGFBR10.38187681
134PAK60.37975364
135RPS6KA50.37832951
136NTRK30.37525388
137MAPK70.34883670
138PRPF4B0.34530251
139BRSK10.34121952
140MAP3K20.33652959
141EPHA30.33602253
142CLK10.33418674
143SYK0.32126487
144WNK30.31936336

Predicted pathways (KEGG)

RankGene SetZ-score
1RNA polymerase_Homo sapiens_hsa030203.38889031
2DNA replication_Homo sapiens_hsa030303.18764392
3Proteasome_Homo sapiens_hsa030503.15963677
4Mismatch repair_Homo sapiens_hsa034303.08999674
5Homologous recombination_Homo sapiens_hsa034402.81049023
6Fanconi anemia pathway_Homo sapiens_hsa034602.80553939
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.71684869
8Ribosome_Homo sapiens_hsa030102.68865845
9Base excision repair_Homo sapiens_hsa034102.50587462
10Pyrimidine metabolism_Homo sapiens_hsa002402.44775424
11Basal transcription factors_Homo sapiens_hsa030222.38804563
12Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.24556866
13Phototransduction_Homo sapiens_hsa047442.23353902
14Protein export_Homo sapiens_hsa030602.16833536
15Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.12473646
16Nucleotide excision repair_Homo sapiens_hsa034202.11850338
17Spliceosome_Homo sapiens_hsa030402.10506180
18Non-homologous end-joining_Homo sapiens_hsa034502.04217442
19Pantothenate and CoA biosynthesis_Homo sapiens_hsa007702.00142845
20One carbon pool by folate_Homo sapiens_hsa006701.96179792
21Nitrogen metabolism_Homo sapiens_hsa009101.92792895
22Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.89153391
23Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.74441863
24Butanoate metabolism_Homo sapiens_hsa006501.65039544
25RNA degradation_Homo sapiens_hsa030181.63877121
26Purine metabolism_Homo sapiens_hsa002301.58248521
27Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.53102150
28Sulfur metabolism_Homo sapiens_hsa009201.51189070
29RNA transport_Homo sapiens_hsa030131.48954679
30Allograft rejection_Homo sapiens_hsa053301.37495149
31Cell cycle_Homo sapiens_hsa041101.33334184
32Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.31868937
33Ether lipid metabolism_Homo sapiens_hsa005651.27914537
34Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.23665242
35Graft-versus-host disease_Homo sapiens_hsa053321.23100987
36Drug metabolism - other enzymes_Homo sapiens_hsa009831.23049975
37Oxidative phosphorylation_Homo sapiens_hsa001901.22660908
38Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.20629595
39Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.17304497
40Collecting duct acid secretion_Homo sapiens_hsa049661.16285794
41Folate biosynthesis_Homo sapiens_hsa007901.16025152
42Maturity onset diabetes of the young_Homo sapiens_hsa049501.15989586
43Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.13943633
44Caffeine metabolism_Homo sapiens_hsa002321.12229127
45SNARE interactions in vesicular transport_Homo sapiens_hsa041301.11521045
46Intestinal immune network for IgA production_Homo sapiens_hsa046721.05500584
47Regulation of autophagy_Homo sapiens_hsa041401.05461951
48Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.02617092
49Vitamin B6 metabolism_Homo sapiens_hsa007501.02456916
50Parkinsons disease_Homo sapiens_hsa050121.00181960
51Autoimmune thyroid disease_Homo sapiens_hsa053200.96675939
52Huntingtons disease_Homo sapiens_hsa050160.95898005
53p53 signaling pathway_Homo sapiens_hsa041150.93658301
54beta-Alanine metabolism_Homo sapiens_hsa004100.89460862
55Steroid hormone biosynthesis_Homo sapiens_hsa001400.89323893
56Retinol metabolism_Homo sapiens_hsa008300.89257879
57Pentose and glucuronate interconversions_Homo sapiens_hsa000400.89011220
58Systemic lupus erythematosus_Homo sapiens_hsa053220.88776622
59Peroxisome_Homo sapiens_hsa041460.86943880
60Herpes simplex infection_Homo sapiens_hsa051680.83897208
61Primary immunodeficiency_Homo sapiens_hsa053400.83827194
62Vitamin digestion and absorption_Homo sapiens_hsa049770.83473220
63Arachidonic acid metabolism_Homo sapiens_hsa005900.83254335
64Other glycan degradation_Homo sapiens_hsa005110.80948141
65Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.79953564
66Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.77673303
67NF-kappa B signaling pathway_Homo sapiens_hsa040640.77664631
68Metabolic pathways_Homo sapiens_hsa011000.74594855
69Cardiac muscle contraction_Homo sapiens_hsa042600.74394774
70Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.73508348
71Sphingolipid metabolism_Homo sapiens_hsa006000.72306434
72Sulfur relay system_Homo sapiens_hsa041220.71656543
73Type I diabetes mellitus_Homo sapiens_hsa049400.71529639
74Epstein-Barr virus infection_Homo sapiens_hsa051690.71193604
75Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.68916214
76N-Glycan biosynthesis_Homo sapiens_hsa005100.68608681
77Cysteine and methionine metabolism_Homo sapiens_hsa002700.67348718
78Selenocompound metabolism_Homo sapiens_hsa004500.66067014
79Measles_Homo sapiens_hsa051620.65265563
80Legionellosis_Homo sapiens_hsa051340.64071371
81Hematopoietic cell lineage_Homo sapiens_hsa046400.63612708
82Histidine metabolism_Homo sapiens_hsa003400.63286847
83Nicotine addiction_Homo sapiens_hsa050330.62406318
84Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.62016276
85RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.61511623
86mRNA surveillance pathway_Homo sapiens_hsa030150.61066833
87Glutathione metabolism_Homo sapiens_hsa004800.60706864
88Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.59889514
89Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.58652574
90Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.58234988
91Olfactory transduction_Homo sapiens_hsa047400.57957530
92Chemical carcinogenesis_Homo sapiens_hsa052040.55784558
93ABC transporters_Homo sapiens_hsa020100.54959209
94Phenylalanine metabolism_Homo sapiens_hsa003600.54675438
95Pentose phosphate pathway_Homo sapiens_hsa000300.53800147
96Tyrosine metabolism_Homo sapiens_hsa003500.52966382
97Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.51762997
98Primary bile acid biosynthesis_Homo sapiens_hsa001200.51631849
99Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.51393199
100Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.50091822
101Linoleic acid metabolism_Homo sapiens_hsa005910.50082243
102Arginine and proline metabolism_Homo sapiens_hsa003300.49443793
103Taste transduction_Homo sapiens_hsa047420.46307733
104Steroid biosynthesis_Homo sapiens_hsa001000.45991541
105Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.43886744
106Alzheimers disease_Homo sapiens_hsa050100.42648356
107Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.40393871
108Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.40209529
109Tryptophan metabolism_Homo sapiens_hsa003800.38122499
110NOD-like receptor signaling pathway_Homo sapiens_hsa046210.37590728
111Asthma_Homo sapiens_hsa053100.37027126
112Fatty acid elongation_Homo sapiens_hsa000620.35508481
113Antigen processing and presentation_Homo sapiens_hsa046120.33104605
114Rheumatoid arthritis_Homo sapiens_hsa053230.31592663
115alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.30800517
116Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.30541849
117Starch and sucrose metabolism_Homo sapiens_hsa005000.29480473
118Propanoate metabolism_Homo sapiens_hsa006400.27508338

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