

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | response to pheromone (GO:0019236) | 7.64649021 |
| 2 | cytidine deamination (GO:0009972) | 7.33464414 |
| 3 | cytidine metabolic process (GO:0046087) | 7.33464414 |
| 4 | cytidine catabolic process (GO:0006216) | 7.33464414 |
| 5 | DNA deamination (GO:0045006) | 7.11263764 |
| 6 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 6.28731408 |
| 7 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 6.25877730 |
| 8 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 5.68208740 |
| 9 | negative regulation by host of viral transcription (GO:0043922) | 4.66643987 |
| 10 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 4.62075383 |
| 11 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.55607265 |
| 12 | cellular ketone body metabolic process (GO:0046950) | 4.34064764 |
| 13 | platelet dense granule organization (GO:0060155) | 4.29772194 |
| 14 | positive T cell selection (GO:0043368) | 4.21459928 |
| 15 | positive regulation of interleukin-8 secretion (GO:2000484) | 4.20617612 |
| 16 | positive thymic T cell selection (GO:0045059) | 4.03467068 |
| 17 | DNA demethylation (GO:0080111) | 4.01035613 |
| 18 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.95896189 |
| 19 | cytochrome complex assembly (GO:0017004) | 3.92096736 |
| 20 | respiratory chain complex IV assembly (GO:0008535) | 3.91320891 |
| 21 | ketone body metabolic process (GO:1902224) | 3.85797639 |
| 22 | positive regulation of defense response to virus by host (GO:0002230) | 3.85231596 |
| 23 | ATP synthesis coupled proton transport (GO:0015986) | 3.83070632 |
| 24 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.83070632 |
| 25 | protein-cofactor linkage (GO:0018065) | 3.81051168 |
| 26 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.70758769 |
| 27 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.70758769 |
| 28 | protein complex biogenesis (GO:0070271) | 3.69888194 |
| 29 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.63998691 |
| 30 | sequestering of actin monomers (GO:0042989) | 3.59944411 |
| 31 | eosinophil chemotaxis (GO:0048245) | 3.58497376 |
| 32 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.58048853 |
| 33 | respiratory electron transport chain (GO:0022904) | 3.55780707 |
| 34 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.55086141 |
| 35 | electron transport chain (GO:0022900) | 3.50829648 |
| 36 | positive regulation of T cell differentiation in thymus (GO:0033089) | 3.45446449 |
| 37 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.30010718 |
| 38 | DNA dealkylation (GO:0035510) | 3.28117628 |
| 39 | eosinophil migration (GO:0072677) | 3.24198028 |
| 40 | ribosomal small subunit assembly (GO:0000028) | 3.24146409 |
| 41 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.17845793 |
| 42 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.17845793 |
| 43 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.17845793 |
| 44 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.15937669 |
| 45 | iron-sulfur cluster assembly (GO:0016226) | 3.15724437 |
| 46 | metallo-sulfur cluster assembly (GO:0031163) | 3.15724437 |
| 47 | negative regulation of T cell apoptotic process (GO:0070233) | 3.15367105 |
| 48 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.14193913 |
| 49 | protein neddylation (GO:0045116) | 3.11674234 |
| 50 | chaperone-mediated protein transport (GO:0072321) | 3.11552369 |
| 51 | cellular response to interleukin-15 (GO:0071350) | 3.10320348 |
| 52 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.06641813 |
| 53 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.05195175 |
| 54 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.05195175 |
| 55 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.04858607 |
| 56 | regulation of interleukin-8 secretion (GO:2000482) | 3.01943296 |
| 57 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.00004052 |
| 58 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.00004052 |
| 59 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.96606973 |
| 60 | rRNA catabolic process (GO:0016075) | 2.93031010 |
| 61 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.92743469 |
| 62 | terpenoid biosynthetic process (GO:0016114) | 2.92590201 |
| 63 | regulation of activation of Janus kinase activity (GO:0010533) | 2.87874611 |
| 64 | proteasome assembly (GO:0043248) | 2.83790229 |
| 65 | purine nucleobase biosynthetic process (GO:0009113) | 2.82811684 |
| 66 | maturation of SSU-rRNA (GO:0030490) | 2.82142362 |
| 67 | pyrimidine nucleoside catabolic process (GO:0046135) | 2.78701797 |
| 68 | natural killer cell activation (GO:0030101) | 2.78142958 |
| 69 | negative regulation of thymocyte apoptotic process (GO:0070244) | 2.77450279 |
| 70 | mitochondrial DNA replication (GO:0006264) | 2.77387327 |
| 71 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2.75950260 |
| 72 | regulation of memory T cell differentiation (GO:0043380) | 2.74699582 |
| 73 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.73862819 |
| 74 | negative regulation of ligase activity (GO:0051352) | 2.73862819 |
| 75 | kynurenine metabolic process (GO:0070189) | 2.72223814 |
| 76 | cytolysis (GO:0019835) | 2.71320981 |
| 77 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.70325065 |
| 78 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.70325065 |
| 79 | postreplication repair (GO:0006301) | 2.69508738 |
| 80 | CENP-A containing nucleosome assembly (GO:0034080) | 2.69458607 |
| 81 | chromatin remodeling at centromere (GO:0031055) | 2.68085414 |
| 82 | regulation of meiosis I (GO:0060631) | 2.67260006 |
| 83 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.62903777 |
| 84 | maturation of 5.8S rRNA (GO:0000460) | 2.59907462 |
| 85 | modulation by host of symbiont transcription (GO:0052472) | 2.58423639 |
| 86 | modulation by host of viral transcription (GO:0043921) | 2.58423639 |
| 87 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.58187713 |
| 88 | S-adenosylmethionine metabolic process (GO:0046500) | 2.57999834 |
| 89 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2.57965712 |
| 90 | regulation of cilium movement (GO:0003352) | 2.52712856 |
| 91 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.50470654 |
| 92 | NADH dehydrogenase complex assembly (GO:0010257) | 2.50470654 |
| 93 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.50470654 |
| 94 | negative T cell selection (GO:0043383) | 2.49841611 |
| 95 | regulation of germinal center formation (GO:0002634) | 2.49511644 |
| 96 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.48813536 |
| 97 | nephron tubule morphogenesis (GO:0072078) | 2.47994818 |
| 98 | nephron epithelium morphogenesis (GO:0072088) | 2.47994818 |
| 99 | modulation of transcription in other organism involved in symbiotic interaction (GO:0052312) | 2.47706316 |
| 100 | inner mitochondrial membrane organization (GO:0007007) | 2.47261370 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.31997034 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.11932117 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.98338556 |
| 4 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.62302979 |
| 5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.54346665 |
| 6 | IGF1R_20145208_ChIP-Seq_DFB_Human | 3.12006624 |
| 7 | VDR_22108803_ChIP-Seq_LS180_Human | 3.03749936 |
| 8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.95543622 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.85980691 |
| 10 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.84717274 |
| 11 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.83378044 |
| 12 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.72638660 |
| 13 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.58188086 |
| 14 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.47903161 |
| 15 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.42942739 |
| 16 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.37615590 |
| 17 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.31647196 |
| 18 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.16285127 |
| 19 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.13288679 |
| 20 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.07782784 |
| 21 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.02986444 |
| 22 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.96488108 |
| 23 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.90141138 |
| 24 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.87965794 |
| 25 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.86501005 |
| 26 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.83844347 |
| 27 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.72426922 |
| 28 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.65653565 |
| 29 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.63478905 |
| 30 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.61361968 |
| 31 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.60577065 |
| 32 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.58218246 |
| 33 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.57816214 |
| 34 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.48717059 |
| 35 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.43334281 |
| 36 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.39508519 |
| 37 | GATA3_26560356_Chip-Seq_TH2_Human | 1.34647331 |
| 38 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.34516951 |
| 39 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.31180027 |
| 40 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.30887980 |
| 41 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.30003593 |
| 42 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.29585896 |
| 43 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.28954010 |
| 44 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.28829953 |
| 45 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.27165941 |
| 46 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.26531531 |
| 47 | RBPJ_21746931_ChIP-Seq_IB4_Human | 1.25732206 |
| 48 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.23693685 |
| 49 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.23614055 |
| 50 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.22805897 |
| 51 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.22461052 |
| 52 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.22461052 |
| 53 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.22354511 |
| 54 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.21685589 |
| 55 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.19483662 |
| 56 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.19455358 |
| 57 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.19368896 |
| 58 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.18864537 |
| 59 | FUS_26573619_Chip-Seq_HEK293_Human | 1.18712385 |
| 60 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.18426797 |
| 61 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.16804220 |
| 62 | MYB_26560356_Chip-Seq_TH2_Human | 1.16285515 |
| 63 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.15294614 |
| 64 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.15294614 |
| 65 | P300_19829295_ChIP-Seq_ESCs_Human | 1.15283082 |
| 66 | PHF8_20622853_ChIP-Seq_HELA_Human | 1.14631919 |
| 67 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.13493457 |
| 68 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.13095013 |
| 69 | AR_20517297_ChIP-Seq_VCAP_Human | 1.12860516 |
| 70 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.11543714 |
| 71 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.11377141 |
| 72 | ETV1_20927104_ChIP-Seq_GIST48_Human | 1.10629677 |
| 73 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.10234976 |
| 74 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.09653901 |
| 75 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.07822728 |
| 76 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.07220662 |
| 77 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.07088436 |
| 78 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.06734189 |
| 79 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.06147628 |
| 80 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.06147628 |
| 81 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.05413156 |
| 82 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.05168739 |
| 83 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.04547137 |
| 84 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.03873132 |
| 85 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.03620503 |
| 86 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.03508548 |
| 87 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.03098385 |
| 88 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.01117029 |
| 89 | NCOR_22424771_ChIP-Seq_293T_Human | 1.00429652 |
| 90 | EWS_26573619_Chip-Seq_HEK293_Human | 0.99588069 |
| 91 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.98417228 |
| 92 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.97970369 |
| 93 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.97668710 |
| 94 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 0.97612120 |
| 95 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.97450645 |
| 96 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.95831647 |
| 97 | NFYB_21822215_ChIP-Seq_K562_Human | 0.94958468 |
| 98 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.94294821 |
| 99 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.92510645 |
| 100 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 0.92191410 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 5.33581535 |
| 2 | MP0001188_hyperpigmentation | 4.07147788 |
| 3 | MP0005671_abnormal_response_to | 3.61356328 |
| 4 | MP0003011_delayed_dark_adaptation | 3.34289005 |
| 5 | MP0003786_premature_aging | 3.00330020 |
| 6 | MP0005377_hearing/vestibular/ear_phenot | 2.99183885 |
| 7 | MP0003878_abnormal_ear_physiology | 2.99183885 |
| 8 | MP0003195_calcinosis | 2.81018311 |
| 9 | MP0009785_altered_susceptibility_to | 2.72810451 |
| 10 | MP0002102_abnormal_ear_morphology | 2.42711790 |
| 11 | MP0002138_abnormal_hepatobiliary_system | 2.39789904 |
| 12 | MP0003763_abnormal_thymus_physiology | 2.22930146 |
| 13 | MP0000372_irregular_coat_pigmentation | 2.21395600 |
| 14 | MP0002234_abnormal_pharynx_morphology | 2.14343525 |
| 15 | MP0006082_CNS_inflammation | 2.01914607 |
| 16 | MP0008875_abnormal_xenobiotic_pharmacok | 2.00623959 |
| 17 | MP0005084_abnormal_gallbladder_morpholo | 1.97915137 |
| 18 | MP0004145_abnormal_muscle_electrophysio | 1.84137599 |
| 19 | MP0001835_abnormal_antigen_presentation | 1.82431101 |
| 20 | MP0002148_abnormal_hypersensitivity_rea | 1.82079165 |
| 21 | MP0002139_abnormal_hepatobiliary_system | 1.67907847 |
| 22 | MP0003283_abnormal_digestive_organ | 1.59026744 |
| 23 | MP0004043_abnormal_pH_regulation | 1.55599249 |
| 24 | MP0003567_abnormal_fetal_cardiomyocyte | 1.53312812 |
| 25 | MP0005645_abnormal_hypothalamus_physiol | 1.50746725 |
| 26 | MP0005075_abnormal_melanosome_morpholog | 1.49668621 |
| 27 | MP0001485_abnormal_pinna_reflex | 1.48037054 |
| 28 | MP0008872_abnormal_physiological_respon | 1.46088193 |
| 29 | MP0002876_abnormal_thyroid_physiology | 1.37001041 |
| 30 | MP0002166_altered_tumor_susceptibility | 1.34081926 |
| 31 | MP0005174_abnormal_tail_pigmentation | 1.33995052 |
| 32 | MP0005000_abnormal_immune_tolerance | 1.33991806 |
| 33 | MP0001800_abnormal_humoral_immune | 1.32132112 |
| 34 | MP0002736_abnormal_nociception_after | 1.29592800 |
| 35 | MP0001501_abnormal_sleep_pattern | 1.28111690 |
| 36 | MP0003724_increased_susceptibility_to | 1.25085498 |
| 37 | MP0001764_abnormal_homeostasis | 1.24248448 |
| 38 | MP0002723_abnormal_immune_serum | 1.23760582 |
| 39 | MP0002277_abnormal_respiratory_mucosa | 1.22292948 |
| 40 | MP0006036_abnormal_mitochondrial_physio | 1.20518263 |
| 41 | MP0001968_abnormal_touch/_nociception | 1.20279842 |
| 42 | MP0001984_abnormal_olfaction | 1.20143139 |
| 43 | MP0008877_abnormal_DNA_methylation | 1.18122887 |
| 44 | MP0008058_abnormal_DNA_repair | 1.18103680 |
| 45 | MP0002420_abnormal_adaptive_immunity | 1.17160622 |
| 46 | MP0004957_abnormal_blastocyst_morpholog | 1.16466890 |
| 47 | MP0001819_abnormal_immune_cell | 1.15419676 |
| 48 | MP0002006_tumorigenesis | 1.11733181 |
| 49 | MP0006276_abnormal_autonomic_nervous | 1.09683634 |
| 50 | MP0002837_dystrophic_cardiac_calcinosis | 1.09628459 |
| 51 | MP0006072_abnormal_retinal_apoptosis | 1.09037298 |
| 52 | MP0005025_abnormal_response_to | 1.08715737 |
| 53 | MP0003866_abnormal_defecation | 1.08447897 |
| 54 | MP0010155_abnormal_intestine_physiology | 1.07444746 |
| 55 | MP0009333_abnormal_splenocyte_physiolog | 1.05705008 |
| 56 | MP0004147_increased_porphyrin_level | 1.03093082 |
| 57 | MP0001661_extended_life_span | 1.02778203 |
| 58 | MP0003186_abnormal_redox_activity | 0.99529707 |
| 59 | MP0000689_abnormal_spleen_morphology | 0.99443845 |
| 60 | MP0008995_early_reproductive_senescence | 0.98868433 |
| 61 | MP0005551_abnormal_eye_electrophysiolog | 0.98511421 |
| 62 | MP0001529_abnormal_vocalization | 0.98447024 |
| 63 | MP0002638_abnormal_pupillary_reflex | 0.97995005 |
| 64 | MP0002398_abnormal_bone_marrow | 0.96488279 |
| 65 | MP0001919_abnormal_reproductive_system | 0.95424253 |
| 66 | MP0002722_abnormal_immune_system | 0.95416929 |
| 67 | MP0003693_abnormal_embryo_hatching | 0.93802562 |
| 68 | MP0000703_abnormal_thymus_morphology | 0.93120697 |
| 69 | MP0005167_abnormal_blood-brain_barrier | 0.92532281 |
| 70 | MP0003252_abnormal_bile_duct | 0.91100688 |
| 71 | MP0002452_abnormal_antigen_presenting | 0.90960922 |
| 72 | MP0002095_abnormal_skin_pigmentation | 0.89720850 |
| 73 | MP0000716_abnormal_immune_system | 0.89531735 |
| 74 | MP0001790_abnormal_immune_system | 0.89518313 |
| 75 | MP0005387_immune_system_phenotype | 0.89518313 |
| 76 | MP0005253_abnormal_eye_physiology | 0.89062890 |
| 77 | MP0005389_reproductive_system_phenotype | 0.87297267 |
| 78 | MP0005464_abnormal_platelet_physiology | 0.87226497 |
| 79 | MP0001986_abnormal_taste_sensitivity | 0.86580355 |
| 80 | MP0003646_muscle_fatigue | 0.86128309 |
| 81 | MP0001119_abnormal_female_reproductive | 0.83675082 |
| 82 | MP0003119_abnormal_digestive_system | 0.80560126 |
| 83 | MP0010386_abnormal_urinary_bladder | 0.80019865 |
| 84 | MP0002282_abnormal_trachea_morphology | 0.79461363 |
| 85 | MP0006035_abnormal_mitochondrial_morpho | 0.79391950 |
| 86 | MP0000013_abnormal_adipose_tissue | 0.78450756 |
| 87 | MP0002210_abnormal_sex_determination | 0.76400752 |
| 88 | MP0005379_endocrine/exocrine_gland_phen | 0.76328025 |
| 89 | MP0009764_decreased_sensitivity_to | 0.75377102 |
| 90 | MP0001765_abnormal_ion_homeostasis | 0.72093725 |
| 91 | MP0001293_anophthalmia | 0.71666821 |
| 92 | MP0000685_abnormal_immune_system | 0.71427248 |
| 93 | MP0002733_abnormal_thermal_nociception | 0.69468224 |
| 94 | MP0002429_abnormal_blood_cell | 0.69248765 |
| 95 | MP0002067_abnormal_sensory_capabilities | 0.67237369 |
| 96 | MP0003137_abnormal_impulse_conducting | 0.65423983 |
| 97 | MP0001970_abnormal_pain_threshold | 0.64932324 |
| 98 | MP0009745_abnormal_behavioral_response | 0.63541744 |
| 99 | MP0003936_abnormal_reproductive_system | 0.63532761 |
| 100 | MP0002405_respiratory_system_inflammati | 0.61647819 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | 3-Methylglutaconic aciduria (HP:0003535) | 4.29970218 |
| 2 | Severe combined immunodeficiency (HP:0004430) | 4.27120298 |
| 3 | Acute necrotizing encephalopathy (HP:0006965) | 3.80115527 |
| 4 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.70981715 |
| 5 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.70981715 |
| 6 | Testicular atrophy (HP:0000029) | 3.50260476 |
| 7 | Combined immunodeficiency (HP:0005387) | 3.47337655 |
| 8 | Thyroiditis (HP:0100646) | 3.46663301 |
| 9 | Congenital, generalized hypertrichosis (HP:0004540) | 3.43494232 |
| 10 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.31587176 |
| 11 | Methylmalonic acidemia (HP:0002912) | 3.29174993 |
| 12 | Mitochondrial inheritance (HP:0001427) | 3.28049713 |
| 13 | Increased hepatocellular lipid droplets (HP:0006565) | 3.27834792 |
| 14 | T lymphocytopenia (HP:0005403) | 3.26556257 |
| 15 | Abnormality of T cell number (HP:0011839) | 3.13228445 |
| 16 | IgG deficiency (HP:0004315) | 3.05709704 |
| 17 | Increased intramyocellular lipid droplets (HP:0012240) | 3.05071657 |
| 18 | Abnormality of midbrain morphology (HP:0002418) | 3.03691669 |
| 19 | Molar tooth sign on MRI (HP:0002419) | 3.03691669 |
| 20 | Progressive macrocephaly (HP:0004481) | 2.99668476 |
| 21 | Pancreatic cysts (HP:0001737) | 2.96253517 |
| 22 | Acute encephalopathy (HP:0006846) | 2.93187246 |
| 23 | Abnormality of DNA repair (HP:0003254) | 2.89373294 |
| 24 | Lipid accumulation in hepatocytes (HP:0006561) | 2.86720766 |
| 25 | Congenital stationary night blindness (HP:0007642) | 2.86352710 |
| 26 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.85937177 |
| 27 | Increased CSF lactate (HP:0002490) | 2.85037766 |
| 28 | Bile duct proliferation (HP:0001408) | 2.80496850 |
| 29 | Abnormal biliary tract physiology (HP:0012439) | 2.80496850 |
| 30 | Renal Fanconi syndrome (HP:0001994) | 2.76003827 |
| 31 | Ketoacidosis (HP:0001993) | 2.72910014 |
| 32 | Abnormality of eosinophils (HP:0001879) | 2.68538624 |
| 33 | Abnormal number of erythroid precursors (HP:0012131) | 2.62018500 |
| 34 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.60782876 |
| 35 | Methylmalonic aciduria (HP:0012120) | 2.56250811 |
| 36 | Ketosis (HP:0001946) | 2.54949945 |
| 37 | Pancreatic fibrosis (HP:0100732) | 2.51193088 |
| 38 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.45029230 |
| 39 | Homocystinuria (HP:0002156) | 2.44240765 |
| 40 | Abnormality of homocysteine metabolism (HP:0010919) | 2.44240765 |
| 41 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.41647113 |
| 42 | Metaphyseal dysplasia (HP:0100255) | 2.41058626 |
| 43 | Entropion (HP:0000621) | 2.38519021 |
| 44 | Cerebral edema (HP:0002181) | 2.38500662 |
| 45 | Increased muscle lipid content (HP:0009058) | 2.37334652 |
| 46 | Gout (HP:0001997) | 2.34781530 |
| 47 | Abolished electroretinogram (ERG) (HP:0000550) | 2.34089758 |
| 48 | Hypoplasia of the uterus (HP:0000013) | 2.34048503 |
| 49 | Prostate neoplasm (HP:0100787) | 2.33878590 |
| 50 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.32954192 |
| 51 | Renal cortical cysts (HP:0000803) | 2.31650042 |
| 52 | Dicarboxylic aciduria (HP:0003215) | 2.28099988 |
| 53 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.28099988 |
| 54 | True hermaphroditism (HP:0010459) | 2.26387653 |
| 55 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.26029467 |
| 56 | Abnormality of vitamin B metabolism (HP:0004340) | 2.25606733 |
| 57 | Dyschromatopsia (HP:0007641) | 2.23208837 |
| 58 | Hypoproteinemia (HP:0003075) | 2.22381099 |
| 59 | Abnormality of T cells (HP:0002843) | 2.22336899 |
| 60 | Stenosis of the external auditory canal (HP:0000402) | 2.22203076 |
| 61 | Megaloblastic anemia (HP:0001889) | 2.21489654 |
| 62 | Spastic paraparesis (HP:0002313) | 2.21416679 |
| 63 | Generalized aminoaciduria (HP:0002909) | 2.12905764 |
| 64 | Abnormality of macular pigmentation (HP:0008002) | 2.12087111 |
| 65 | Abnormality of the prostate (HP:0008775) | 2.12071253 |
| 66 | Panhypogammaglobulinemia (HP:0003139) | 2.08302855 |
| 67 | Sparse eyelashes (HP:0000653) | 2.05951555 |
| 68 | Hypothermia (HP:0002045) | 2.04721405 |
| 69 | Metabolic alkalosis (HP:0200114) | 2.03010581 |
| 70 | Exertional dyspnea (HP:0002875) | 2.02773994 |
| 71 | Abnormality of the renal cortex (HP:0011035) | 2.01283893 |
| 72 | Optic disc pallor (HP:0000543) | 1.99396325 |
| 73 | Hepatocellular necrosis (HP:0001404) | 1.94301874 |
| 74 | Encephalitis (HP:0002383) | 1.93310760 |
| 75 | Lethargy (HP:0001254) | 1.92329550 |
| 76 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.90143358 |
| 77 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.89928866 |
| 78 | Flat capital femoral epiphysis (HP:0003370) | 1.89664912 |
| 79 | Delayed CNS myelination (HP:0002188) | 1.88444892 |
| 80 | Unilateral renal agenesis (HP:0000122) | 1.88183360 |
| 81 | CNS hypomyelination (HP:0003429) | 1.87620928 |
| 82 | Carpal bone hypoplasia (HP:0001498) | 1.87015921 |
| 83 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.84781104 |
| 84 | Colon cancer (HP:0003003) | 1.84251108 |
| 85 | Increased serum lactate (HP:0002151) | 1.81915196 |
| 86 | Lactic acidosis (HP:0003128) | 1.81369360 |
| 87 | Bifid tongue (HP:0010297) | 1.79428333 |
| 88 | Hepatic necrosis (HP:0002605) | 1.79026322 |
| 89 | Cerebral hypomyelination (HP:0006808) | 1.78258520 |
| 90 | Abnormality of urine glucose concentration (HP:0011016) | 1.76621097 |
| 91 | Glycosuria (HP:0003076) | 1.76621097 |
| 92 | Tachypnea (HP:0002789) | 1.76170444 |
| 93 | Autoimmune hemolytic anemia (HP:0001890) | 1.75650584 |
| 94 | Shawl scrotum (HP:0000049) | 1.73641578 |
| 95 | Exercise intolerance (HP:0003546) | 1.73241726 |
| 96 | Type 2 muscle fiber atrophy (HP:0003554) | 1.72811312 |
| 97 | Hypokalemic alkalosis (HP:0001949) | 1.72403758 |
| 98 | Leukocytosis (HP:0001974) | 1.72188811 |
| 99 | Abnormal number of incisors (HP:0011064) | 1.69871561 |
| 100 | Eosinophilia (HP:0001880) | 1.69023399 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 3.97756027 |
| 2 | TXK | 3.67568551 |
| 3 | STK16 | 3.62700697 |
| 4 | ZAK | 3.55995654 |
| 5 | TESK2 | 3.38585373 |
| 6 | KDR | 3.10018846 |
| 7 | NUAK1 | 2.95052982 |
| 8 | TAOK3 | 2.64520853 |
| 9 | BUB1 | 2.63222616 |
| 10 | ADRBK2 | 2.39087191 |
| 11 | MAPKAPK3 | 2.30257875 |
| 12 | MUSK | 2.25544581 |
| 13 | TAF1 | 2.08087025 |
| 14 | EIF2AK3 | 2.02983088 |
| 15 | TRIM28 | 1.98408599 |
| 16 | GRK1 | 1.91907631 |
| 17 | VRK1 | 1.86473870 |
| 18 | CDC7 | 1.82236880 |
| 19 | BMPR1B | 1.74540233 |
| 20 | TNIK | 1.69660578 |
| 21 | SRPK1 | 1.66278272 |
| 22 | MAPKAPK5 | 1.61667692 |
| 23 | EEF2K | 1.56466606 |
| 24 | PIK3CA | 1.46216733 |
| 25 | MAP4K2 | 1.45167664 |
| 26 | DYRK2 | 1.37871379 |
| 27 | MAP3K12 | 1.36089031 |
| 28 | EIF2AK1 | 1.34392839 |
| 29 | PLK3 | 1.33408872 |
| 30 | EIF2AK2 | 1.26105895 |
| 31 | TRPM7 | 1.25860995 |
| 32 | WNK4 | 1.24651588 |
| 33 | NEK1 | 1.23929697 |
| 34 | MST4 | 1.18361342 |
| 35 | TLK1 | 1.11769281 |
| 36 | MYLK | 1.02940890 |
| 37 | GRK5 | 0.96859237 |
| 38 | BRSK2 | 0.93531783 |
| 39 | RPS6KB2 | 0.92879113 |
| 40 | NME1 | 0.92164123 |
| 41 | ITK | 0.91879136 |
| 42 | PLK2 | 0.88899413 |
| 43 | FRK | 0.87614858 |
| 44 | SMG1 | 0.87184343 |
| 45 | MAPK13 | 0.84471553 |
| 46 | LIMK1 | 0.83152468 |
| 47 | PRKCQ | 0.80104249 |
| 48 | AKT3 | 0.79319742 |
| 49 | MAP3K14 | 0.78374756 |
| 50 | MAP4K1 | 0.76813499 |
| 51 | SCYL2 | 0.75611698 |
| 52 | MATK | 0.74369795 |
| 53 | TBK1 | 0.72555653 |
| 54 | ADRBK1 | 0.72204883 |
| 55 | BCR | 0.71062467 |
| 56 | CSF1R | 0.70747809 |
| 57 | GRK7 | 0.68492674 |
| 58 | TIE1 | 0.67953169 |
| 59 | MAPK11 | 0.67699215 |
| 60 | BCKDK | 0.63683790 |
| 61 | TTK | 0.61826809 |
| 62 | WNK3 | 0.58302905 |
| 63 | MAP3K11 | 0.56806129 |
| 64 | DAPK1 | 0.56752240 |
| 65 | LCK | 0.54258194 |
| 66 | FES | 0.52824353 |
| 67 | CSNK1G3 | 0.51096750 |
| 68 | INSRR | 0.50699092 |
| 69 | AURKA | 0.49736239 |
| 70 | CASK | 0.49116012 |
| 71 | CHEK2 | 0.48736837 |
| 72 | CDK9 | 0.48516808 |
| 73 | PHKG1 | 0.46686042 |
| 74 | PHKG2 | 0.46686042 |
| 75 | NTRK1 | 0.45893662 |
| 76 | CLK1 | 0.44599008 |
| 77 | MAP2K6 | 0.44358686 |
| 78 | DAPK3 | 0.43013402 |
| 79 | SYK | 0.42720499 |
| 80 | IGF1R | 0.42226353 |
| 81 | CSNK1G2 | 0.41837737 |
| 82 | PBK | 0.41194163 |
| 83 | CSNK2A1 | 0.39716966 |
| 84 | CSNK1A1L | 0.39559540 |
| 85 | IKBKE | 0.38706890 |
| 86 | PLK1 | 0.38218299 |
| 87 | AURKB | 0.36474286 |
| 88 | CSNK1G1 | 0.36236375 |
| 89 | PLK4 | 0.36135561 |
| 90 | ERBB3 | 0.36071725 |
| 91 | GRK6 | 0.35834428 |
| 92 | ACVR1B | 0.35143373 |
| 93 | JAK1 | 0.33033992 |
| 94 | TEC | 0.31485932 |
| 95 | MAP3K4 | 0.30809426 |
| 96 | LRRK2 | 0.29379278 |
| 97 | PRKCE | 0.28893332 |
| 98 | BMPR2 | 0.28397717 |
| 99 | PINK1 | 0.27511076 |
| 100 | IKBKB | 0.27177870 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.48151828 |
| 2 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 4.00021644 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.43499898 |
| 4 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.14531821 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 2.83151960 |
| 6 | Ribosome_Homo sapiens_hsa03010 | 2.42808696 |
| 7 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.25899049 |
| 8 | Protein export_Homo sapiens_hsa03060 | 2.24250958 |
| 9 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.16439709 |
| 10 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.05363808 |
| 11 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.05101060 |
| 12 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.04494051 |
| 13 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.01538760 |
| 14 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.00846334 |
| 15 | Mismatch repair_Homo sapiens_hsa03430 | 2.00344122 |
| 16 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.91522094 |
| 17 | Alzheimers disease_Homo sapiens_hsa05010 | 1.91302285 |
| 18 | Allograft rejection_Homo sapiens_hsa05330 | 1.90735143 |
| 19 | RNA polymerase_Homo sapiens_hsa03020 | 1.79004926 |
| 20 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.78863428 |
| 21 | Huntingtons disease_Homo sapiens_hsa05016 | 1.78741397 |
| 22 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.76018934 |
| 23 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.73374316 |
| 24 | DNA replication_Homo sapiens_hsa03030 | 1.67318121 |
| 25 | Homologous recombination_Homo sapiens_hsa03440 | 1.67251406 |
| 26 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.55562970 |
| 27 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.53661480 |
| 28 | Asthma_Homo sapiens_hsa05310 | 1.42958968 |
| 29 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.42232525 |
| 30 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.40233265 |
| 31 | RNA degradation_Homo sapiens_hsa03018 | 1.39761388 |
| 32 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.38604633 |
| 33 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.34625029 |
| 34 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.33341725 |
| 35 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.27817121 |
| 36 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.26876560 |
| 37 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.26144172 |
| 38 | Spliceosome_Homo sapiens_hsa03040 | 1.26102916 |
| 39 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.15186511 |
| 40 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.03697737 |
| 41 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.02529559 |
| 42 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.00143592 |
| 43 | RNA transport_Homo sapiens_hsa03013 | 1.00090305 |
| 44 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.99053744 |
| 45 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.94934009 |
| 46 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.89825803 |
| 47 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.89332187 |
| 48 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.86253609 |
| 49 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.84250698 |
| 50 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.78507791 |
| 51 | Olfactory transduction_Homo sapiens_hsa04740 | 0.73122639 |
| 52 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.71049147 |
| 53 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.70577888 |
| 54 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.70189364 |
| 55 | Malaria_Homo sapiens_hsa05144 | 0.70136407 |
| 56 | Purine metabolism_Homo sapiens_hsa00230 | 0.70078146 |
| 57 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.69087243 |
| 58 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.67564933 |
| 59 | Peroxisome_Homo sapiens_hsa04146 | 0.67390796 |
| 60 | Retinol metabolism_Homo sapiens_hsa00830 | 0.66242148 |
| 61 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.64902262 |
| 62 | Measles_Homo sapiens_hsa05162 | 0.60314987 |
| 63 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.58578218 |
| 64 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.57379811 |
| 65 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.57194896 |
| 66 | Basal transcription factors_Homo sapiens_hsa03022 | 0.56533201 |
| 67 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.56410818 |
| 68 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.55959985 |
| 69 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.55016707 |
| 70 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.54318646 |
| 71 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.53986646 |
| 72 | Phototransduction_Homo sapiens_hsa04744 | 0.51816127 |
| 73 | Metabolic pathways_Homo sapiens_hsa01100 | 0.51565468 |
| 74 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.50405561 |
| 75 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.50279045 |
| 76 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.50202144 |
| 77 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.46779268 |
| 78 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.45322604 |
| 79 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.44697341 |
| 80 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.43296713 |
| 81 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.43277995 |
| 82 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.41365457 |
| 83 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.40817596 |
| 84 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.40371522 |
| 85 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.39098375 |
| 86 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.36398336 |
| 87 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.35117464 |
| 88 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.33089943 |
| 89 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.32783523 |
| 90 | Salmonella infection_Homo sapiens_hsa05132 | 0.32164042 |
| 91 | Viral myocarditis_Homo sapiens_hsa05416 | 0.32030155 |
| 92 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.30400632 |
| 93 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.30369951 |
| 94 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.27828519 |
| 95 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.26918551 |
| 96 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.26096041 |
| 97 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.23615841 |
| 98 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.23086809 |
| 99 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.22956897 |
| 100 | Salivary secretion_Homo sapiens_hsa04970 | 0.21288404 |

