

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | NIK/NF-kappaB signaling (GO:0038061) | 8.43220070 |
| 2 | urinary tract smooth muscle contraction (GO:0014848) | 6.96465199 |
| 3 | behavioral response to nicotine (GO:0035095) | 6.84053889 |
| 4 | cytoplasmic mRNA processing body assembly (GO:0033962) | 6.24611190 |
| 5 | response to pheromone (GO:0019236) | 6.24023995 |
| 6 | pharyngeal system development (GO:0060037) | 6.04531881 |
| 7 | regulation of gene silencing by RNA (GO:0060966) | 5.20245180 |
| 8 | regulation of posttranscriptional gene silencing (GO:0060147) | 5.20245180 |
| 9 | regulation of gene silencing by miRNA (GO:0060964) | 5.20245180 |
| 10 | spinal cord association neuron differentiation (GO:0021527) | 5.09907123 |
| 11 | necroptotic process (GO:0070266) | 5.08605031 |
| 12 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) | 5.04800061 |
| 13 | regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) | 5.04800061 |
| 14 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.96135257 |
| 15 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.96135257 |
| 16 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 4.63153992 |
| 17 | cerebellar Purkinje cell differentiation (GO:0021702) | 4.62925498 |
| 18 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151) | 4.59916797 |
| 19 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO | 4.59916797 |
| 20 | DNA deamination (GO:0045006) | 4.57957684 |
| 21 | phosphatidylserine acyl-chain remodeling (GO:0036150) | 4.43538155 |
| 22 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 4.40127707 |
| 23 | lymph node development (GO:0048535) | 4.31671263 |
| 24 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 4.30533841 |
| 25 | regulation of action potential (GO:0098900) | 4.24306368 |
| 26 | kynurenine metabolic process (GO:0070189) | 4.20709746 |
| 27 | postsynaptic membrane organization (GO:0001941) | 4.19737206 |
| 28 | peristalsis (GO:0030432) | 4.17576059 |
| 29 | negative regulation of nitric-oxide synthase activity (GO:0051001) | 4.15277093 |
| 30 | aggressive behavior (GO:0002118) | 4.10380547 |
| 31 | cell proliferation in forebrain (GO:0021846) | 4.09026816 |
| 32 | histone H4-K12 acetylation (GO:0043983) | 4.07679512 |
| 33 | positive regulation of action potential (GO:0045760) | 4.06998856 |
| 34 | regulation of T cell mediated cytotoxicity (GO:0001914) | 4.03336159 |
| 35 | behavioral response to pain (GO:0048266) | 4.01766058 |
| 36 | indole-containing compound catabolic process (GO:0042436) | 3.98954212 |
| 37 | indolalkylamine catabolic process (GO:0046218) | 3.98954212 |
| 38 | tryptophan catabolic process (GO:0006569) | 3.98954212 |
| 39 | serotonin metabolic process (GO:0042428) | 3.77606026 |
| 40 | regulation of cellular extravasation (GO:0002691) | 3.75548499 |
| 41 | activated T cell proliferation (GO:0050798) | 3.74745594 |
| 42 | GMP metabolic process (GO:0046037) | 3.73341107 |
| 43 | interkinetic nuclear migration (GO:0022027) | 3.69762046 |
| 44 | embryonic skeletal joint morphogenesis (GO:0060272) | 3.61950170 |
| 45 | positive regulation of mRNA catabolic process (GO:0061014) | 3.60115039 |
| 46 | tachykinin receptor signaling pathway (GO:0007217) | 3.59468760 |
| 47 | positive regulation of mRNA 3-end processing (GO:0031442) | 3.56199699 |
| 48 | opioid receptor signaling pathway (GO:0038003) | 3.54328572 |
| 49 | positive regulation of uterine smooth muscle contraction (GO:0070474) | 3.50629265 |
| 50 | tryptophan metabolic process (GO:0006568) | 3.42386833 |
| 51 | negative regulation by host of viral transcription (GO:0043922) | 3.38135339 |
| 52 | regulation of rhodopsin mediated signaling pathway (GO:0022400) | 3.37813349 |
| 53 | T cell homeostasis (GO:0043029) | 3.36870875 |
| 54 | signal peptide processing (GO:0006465) | 3.35349493 |
| 55 | oogenesis (GO:0048477) | 3.35251005 |
| 56 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 3.34063152 |
| 57 | forebrain neuron differentiation (GO:0021879) | 3.33806606 |
| 58 | cornea development in camera-type eye (GO:0061303) | 3.33594542 |
| 59 | spleen development (GO:0048536) | 3.32932768 |
| 60 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 3.31031072 |
| 61 | programmed necrotic cell death (GO:0097300) | 3.27730600 |
| 62 | necrotic cell death (GO:0070265) | 3.27613315 |
| 63 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.26097101 |
| 64 | negative regulation of monooxygenase activity (GO:0032769) | 3.23929733 |
| 65 | indole-containing compound metabolic process (GO:0042430) | 3.23054665 |
| 66 | phosphatidylethanolamine acyl-chain remodeling (GO:0036152) | 3.19619532 |
| 67 | regulation of germinal center formation (GO:0002634) | 3.19246857 |
| 68 | piRNA metabolic process (GO:0034587) | 3.18348815 |
| 69 | DNA methylation involved in gamete generation (GO:0043046) | 3.12375767 |
| 70 | seminiferous tubule development (GO:0072520) | 3.12039273 |
| 71 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 3.11076362 |
| 72 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 3.11076362 |
| 73 | regulation of translation, ncRNA-mediated (GO:0045974) | 3.11076362 |
| 74 | regulation of female gonad development (GO:2000194) | 3.09463027 |
| 75 | positive regulation by host of viral transcription (GO:0043923) | 3.09054174 |
| 76 | primary amino compound metabolic process (GO:1901160) | 3.08332392 |
| 77 | neuronal action potential (GO:0019228) | 3.05179782 |
| 78 | rhodopsin mediated signaling pathway (GO:0016056) | 3.01641765 |
| 79 | drinking behavior (GO:0042756) | 3.00369587 |
| 80 | sodium-independent organic anion transport (GO:0043252) | 2.92512864 |
| 81 | positive regulation of renal sodium excretion (GO:0035815) | 2.89260201 |
| 82 | regulation of necroptotic process (GO:0060544) | 2.89084431 |
| 83 | regulation of mRNA catabolic process (GO:0061013) | 2.88180053 |
| 84 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 2.85296222 |
| 85 | regulation of uterine smooth muscle contraction (GO:0070472) | 2.84852529 |
| 86 | regulation of mRNA 3-end processing (GO:0031440) | 2.84123732 |
| 87 | purine deoxyribonucleotide catabolic process (GO:0009155) | 2.81821495 |
| 88 | locomotory exploration behavior (GO:0035641) | 2.81594160 |
| 89 | musculoskeletal movement (GO:0050881) | 2.81414186 |
| 90 | multicellular organismal movement (GO:0050879) | 2.81414186 |
| 91 | multicellular organism reproduction (GO:0032504) | 2.79701321 |
| 92 | endoderm formation (GO:0001706) | 2.79679489 |
| 93 | positive regulation of digestive system process (GO:0060456) | 2.77861912 |
| 94 | alanine transport (GO:0032328) | 2.76280207 |
| 95 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339 | 2.75573346 |
| 96 | pantothenate metabolic process (GO:0015939) | 2.73507623 |
| 97 | behavioral response to ethanol (GO:0048149) | 2.73034522 |
| 98 | S-adenosylmethionine metabolic process (GO:0046500) | 2.72737297 |
| 99 | indolalkylamine metabolic process (GO:0006586) | 2.72669495 |
| 100 | sequestering of extracellular ligand from receptor (GO:0035581) | 2.69590011 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.58094801 |
| 2 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.91511746 |
| 3 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.53406009 |
| 4 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.49304575 |
| 5 | IGF1R_20145208_ChIP-Seq_DFB_Human | 3.37944130 |
| 6 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.36448321 |
| 7 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.29428280 |
| 8 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.26909546 |
| 9 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.23853430 |
| 10 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.03869656 |
| 11 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.97756510 |
| 12 | VDR_22108803_ChIP-Seq_LS180_Human | 1.97384493 |
| 13 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.89571787 |
| 14 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.88554802 |
| 15 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.86342737 |
| 16 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.80794477 |
| 17 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.78995249 |
| 18 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.77825906 |
| 19 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.77365970 |
| 20 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.76348720 |
| 21 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.71759889 |
| 22 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.71221465 |
| 23 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.68912164 |
| 24 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.66820016 |
| 25 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.65172455 |
| 26 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.61280830 |
| 27 | EWS_26573619_Chip-Seq_HEK293_Human | 1.57609217 |
| 28 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.55840170 |
| 29 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.54649728 |
| 30 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.54531502 |
| 31 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.53097922 |
| 32 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.52952947 |
| 33 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.51540233 |
| 34 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.51163396 |
| 35 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.50544260 |
| 36 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.47607524 |
| 37 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.43892867 |
| 38 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.42730292 |
| 39 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.42245757 |
| 40 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.41117309 |
| 41 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.38952286 |
| 42 | FUS_26573619_Chip-Seq_HEK293_Human | 1.37796482 |
| 43 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.37332287 |
| 44 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.37326459 |
| 45 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.37326459 |
| 46 | STAT3_23295773_ChIP-Seq_U87_Human | 1.36828483 |
| 47 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.36507574 |
| 48 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.33542979 |
| 49 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.33327568 |
| 50 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.31905110 |
| 51 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.31905110 |
| 52 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.30601521 |
| 53 | P300_19829295_ChIP-Seq_ESCs_Human | 1.28643983 |
| 54 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.26767846 |
| 55 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.26284727 |
| 56 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.26026041 |
| 57 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.25753265 |
| 58 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.24984669 |
| 59 | TCF4_23295773_ChIP-Seq_U87_Human | 1.24857031 |
| 60 | NCOR_22424771_ChIP-Seq_293T_Human | 1.24561721 |
| 61 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.23707813 |
| 62 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.23357222 |
| 63 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.23227790 |
| 64 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.22492240 |
| 65 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.21608289 |
| 66 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.21608289 |
| 67 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.21297631 |
| 68 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.21158539 |
| 69 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.18533606 |
| 70 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.18287384 |
| 71 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.18287384 |
| 72 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.15031005 |
| 73 | AR_25329375_ChIP-Seq_VCAP_Human | 1.14070723 |
| 74 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.13610435 |
| 75 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.12663825 |
| 76 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.11657655 |
| 77 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.11536952 |
| 78 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.11140781 |
| 79 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.11054999 |
| 80 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.10730110 |
| 81 | AR_20517297_ChIP-Seq_VCAP_Human | 1.10539722 |
| 82 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.10448281 |
| 83 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.10431154 |
| 84 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.09950562 |
| 85 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.08642514 |
| 86 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.06900795 |
| 87 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.06603964 |
| 88 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.05602599 |
| 89 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.05227914 |
| 90 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.04289234 |
| 91 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.03545428 |
| 92 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.02905129 |
| 93 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 1.01863108 |
| 94 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.00633374 |
| 95 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.00581208 |
| 96 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.99439858 |
| 97 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 0.99430717 |
| 98 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.98647949 |
| 99 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.97454547 |
| 100 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.97075802 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000372_irregular_coat_pigmentation | 4.51307930 |
| 2 | MP0001968_abnormal_touch/_nociception | 3.97711928 |
| 3 | MP0003136_yellow_coat_color | 3.79162497 |
| 4 | MP0002736_abnormal_nociception_after | 3.32287732 |
| 5 | MP0003646_muscle_fatigue | 2.93351774 |
| 6 | MP0005671_abnormal_response_to | 2.50753132 |
| 7 | MP0005083_abnormal_biliary_tract | 2.50367907 |
| 8 | MP0006082_CNS_inflammation | 2.42635457 |
| 9 | MP0002734_abnormal_mechanical_nocicepti | 2.38302928 |
| 10 | MP0001661_extended_life_span | 2.36429192 |
| 11 | MP0004885_abnormal_endolymph | 2.33952901 |
| 12 | MP0002277_abnormal_respiratory_mucosa | 2.31885756 |
| 13 | MP0001764_abnormal_homeostasis | 2.29891224 |
| 14 | MP0001986_abnormal_taste_sensitivity | 2.28666918 |
| 15 | MP0008877_abnormal_DNA_methylation | 2.07698495 |
| 16 | MP0010368_abnormal_lymphatic_system | 2.07579033 |
| 17 | MP0004142_abnormal_muscle_tone | 1.93231963 |
| 18 | MP0005551_abnormal_eye_electrophysiolog | 1.90934906 |
| 19 | MP0001529_abnormal_vocalization | 1.88981417 |
| 20 | MP0009745_abnormal_behavioral_response | 1.75770179 |
| 21 | MP0001501_abnormal_sleep_pattern | 1.75315616 |
| 22 | MP0002876_abnormal_thyroid_physiology | 1.68378545 |
| 23 | MP0006292_abnormal_olfactory_placode | 1.65669585 |
| 24 | MP0004133_heterotaxia | 1.65008405 |
| 25 | MP0002163_abnormal_gland_morphology | 1.61333663 |
| 26 | MP0008875_abnormal_xenobiotic_pharmacok | 1.59830797 |
| 27 | MP0008872_abnormal_physiological_respon | 1.56399485 |
| 28 | MP0002933_joint_inflammation | 1.55962858 |
| 29 | MP0002735_abnormal_chemical_nociception | 1.55091598 |
| 30 | MP0000685_abnormal_immune_system | 1.53539240 |
| 31 | MP0009046_muscle_twitch | 1.50120827 |
| 32 | MP0002272_abnormal_nervous_system | 1.48833508 |
| 33 | MP0001485_abnormal_pinna_reflex | 1.47996777 |
| 34 | MP0005423_abnormal_somatic_nervous | 1.46731034 |
| 35 | MP0005253_abnormal_eye_physiology | 1.45548502 |
| 36 | MP0006276_abnormal_autonomic_nervous | 1.45397440 |
| 37 | MP0003195_calcinosis | 1.43561649 |
| 38 | MP0008874_decreased_physiological_sensi | 1.42692097 |
| 39 | MP0002837_dystrophic_cardiac_calcinosis | 1.39584995 |
| 40 | MP0000569_abnormal_digit_pigmentation | 1.38674537 |
| 41 | MP0002132_abnormal_respiratory_system | 1.34880047 |
| 42 | MP0004084_abnormal_cardiac_muscle | 1.33064408 |
| 43 | MP0005220_abnormal_exocrine_pancreas | 1.31649883 |
| 44 | MP0002557_abnormal_social/conspecific_i | 1.28556406 |
| 45 | MP0003183_abnormal_peptide_metabolism | 1.28503838 |
| 46 | MP0008057_abnormal_DNA_replication | 1.26304057 |
| 47 | MP0005646_abnormal_pituitary_gland | 1.22819678 |
| 48 | MP0002572_abnormal_emotion/affect_behav | 1.22453300 |
| 49 | MP0000013_abnormal_adipose_tissue | 1.22113010 |
| 50 | MP0005075_abnormal_melanosome_morpholog | 1.19610610 |
| 51 | MP0001970_abnormal_pain_threshold | 1.15171246 |
| 52 | MP0004381_abnormal_hair_follicle | 1.12585192 |
| 53 | MP0003638_abnormal_response/metabolism_ | 1.08440294 |
| 54 | MP0004145_abnormal_muscle_electrophysio | 1.05046804 |
| 55 | MP0002064_seizures | 1.03356361 |
| 56 | MP0003283_abnormal_digestive_organ | 1.01688792 |
| 57 | MP0001486_abnormal_startle_reflex | 1.00156612 |
| 58 | MP0000778_abnormal_nervous_system | 0.96944306 |
| 59 | MP0009384_cardiac_valve_regurgitation | 0.95848461 |
| 60 | MP0001800_abnormal_humoral_immune | 0.94295684 |
| 61 | MP0002063_abnormal_learning/memory/cond | 0.92515726 |
| 62 | MP0004019_abnormal_vitamin_homeostasis | 0.91978151 |
| 63 | MP0002234_abnormal_pharynx_morphology | 0.91656874 |
| 64 | MP0004924_abnormal_behavior | 0.90910795 |
| 65 | MP0005386_behavior/neurological_phenoty | 0.90910795 |
| 66 | MP0008569_lethality_at_weaning | 0.90428966 |
| 67 | MP0000631_abnormal_neuroendocrine_gland | 0.90263744 |
| 68 | MP0003690_abnormal_glial_cell | 0.89804392 |
| 69 | MP0001440_abnormal_grooming_behavior | 0.89281316 |
| 70 | MP0001790_abnormal_immune_system | 0.86434001 |
| 71 | MP0005387_immune_system_phenotype | 0.86434001 |
| 72 | MP0000230_abnormal_systemic_arterial | 0.85567983 |
| 73 | MP0002067_abnormal_sensory_capabilities | 0.83763410 |
| 74 | MP0001502_abnormal_circadian_rhythm | 0.83301816 |
| 75 | MP0003763_abnormal_thymus_physiology | 0.82644878 |
| 76 | MP0002693_abnormal_pancreas_physiology | 0.82599304 |
| 77 | MP0002210_abnormal_sex_determination | 0.81542218 |
| 78 | MP0005195_abnormal_posterior_eye | 0.81300068 |
| 79 | MP0005376_homeostasis/metabolism_phenot | 0.81041231 |
| 80 | MP0003943_abnormal_hepatobiliary_system | 0.81028061 |
| 81 | MP0003866_abnormal_defecation | 0.79470361 |
| 82 | MP0000026_abnormal_inner_ear | 0.79307726 |
| 83 | MP0003137_abnormal_impulse_conducting | 0.78727341 |
| 84 | MP0002733_abnormal_thermal_nociception | 0.77977249 |
| 85 | MP0003635_abnormal_synaptic_transmissio | 0.77412364 |
| 86 | MP0003950_abnormal_plasma_membrane | 0.76462250 |
| 87 | MP0003045_fibrosis | 0.76022474 |
| 88 | MP0003119_abnormal_digestive_system | 0.75178232 |
| 89 | MP0004043_abnormal_pH_regulation | 0.73893590 |
| 90 | MP0005410_abnormal_fertilization | 0.73615871 |
| 91 | MP0001324_abnormal_eye_pigmentation | 0.72816292 |
| 92 | MP0008004_abnormal_stomach_pH | 0.71259676 |
| 93 | MP0004147_increased_porphyrin_level | 0.70912495 |
| 94 | MP0001929_abnormal_gametogenesis | 0.69512114 |
| 95 | MP0001765_abnormal_ion_homeostasis | 0.68014287 |
| 96 | MP0005266_abnormal_metabolism | 0.67573643 |
| 97 | MP0005379_endocrine/exocrine_gland_phen | 0.67246253 |
| 98 | MP0005167_abnormal_blood-brain_barrier | 0.65760141 |
| 99 | MP0001963_abnormal_hearing_physiology | 0.65575577 |
| 100 | MP0000639_abnormal_adrenal_gland | 0.65524864 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of the pons (HP:0007361) | 6.49747141 |
| 2 | Hypoplasia of the pons (HP:0012110) | 6.35632399 |
| 3 | Biconcave vertebral bodies (HP:0004586) | 4.61885623 |
| 4 | Congenital stationary night blindness (HP:0007642) | 4.37321751 |
| 5 | Abnormality of the vertebral endplates (HP:0005106) | 4.33780753 |
| 6 | Cerebral palsy (HP:0100021) | 3.56547214 |
| 7 | Hyperventilation (HP:0002883) | 3.46609512 |
| 8 | Poor suck (HP:0002033) | 3.46131754 |
| 9 | Type II lissencephaly (HP:0007260) | 3.35811478 |
| 10 | Hyperlipoproteinemia (HP:0010980) | 3.35063577 |
| 11 | Pancreatic fibrosis (HP:0100732) | 3.33322908 |
| 12 | Acute lymphatic leukemia (HP:0006721) | 3.17698862 |
| 13 | Attenuation of retinal blood vessels (HP:0007843) | 3.14075640 |
| 14 | Abnormality of the femoral head (HP:0003368) | 3.01464749 |
| 15 | Irregular vertebral endplates (HP:0003301) | 2.97461228 |
| 16 | Abnormality of cochlea (HP:0000375) | 2.93781661 |
| 17 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.87916308 |
| 18 | True hermaphroditism (HP:0010459) | 2.86286509 |
| 19 | Flat capital femoral epiphysis (HP:0003370) | 2.84706960 |
| 20 | Broad-based gait (HP:0002136) | 2.82265217 |
| 21 | Abnormality of the renal collecting system (HP:0004742) | 2.79586887 |
| 22 | Pancreatic cysts (HP:0001737) | 2.76618889 |
| 23 | Visual hallucinations (HP:0002367) | 2.75711189 |
| 24 | Duplicated collecting system (HP:0000081) | 2.72968185 |
| 25 | Neurodegeneration (HP:0002180) | 2.71196412 |
| 26 | Abnormality of secondary sexual hair (HP:0009888) | 2.67437415 |
| 27 | Abnormality of the axillary hair (HP:0100134) | 2.67437415 |
| 28 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.67335872 |
| 29 | Abnormality of alanine metabolism (HP:0010916) | 2.67335872 |
| 30 | Hyperalaninemia (HP:0003348) | 2.67335872 |
| 31 | Type 2 muscle fiber atrophy (HP:0003554) | 2.67079615 |
| 32 | Hypoproteinemia (HP:0003075) | 2.66997374 |
| 33 | Dyskinesia (HP:0100660) | 2.62842852 |
| 34 | Morphological abnormality of the inner ear (HP:0011390) | 2.60665686 |
| 35 | J-shaped sella turcica (HP:0002680) | 2.57806814 |
| 36 | Broad face (HP:0000283) | 2.56261706 |
| 37 | Inability to walk (HP:0002540) | 2.54541178 |
| 38 | Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108) | 2.52058237 |
| 39 | Chin dimple (HP:0010751) | 2.51359300 |
| 40 | Genetic anticipation (HP:0003743) | 2.50437081 |
| 41 | Abnormality of the epiphysis of the femoral head (HP:0010574) | 2.47407587 |
| 42 | Dysautonomia (HP:0002459) | 2.47239984 |
| 43 | Impaired smooth pursuit (HP:0007772) | 2.46447812 |
| 44 | Cerebellar dysplasia (HP:0007033) | 2.46318758 |
| 45 | Molar tooth sign on MRI (HP:0002419) | 2.46267596 |
| 46 | Abnormality of midbrain morphology (HP:0002418) | 2.46267596 |
| 47 | Abnormality of proline metabolism (HP:0010907) | 2.45601959 |
| 48 | Hydroxyprolinuria (HP:0003080) | 2.45601959 |
| 49 | Ulnar claw (HP:0001178) | 2.42004645 |
| 50 | Chorioretinal atrophy (HP:0000533) | 2.38948202 |
| 51 | Opisthotonus (HP:0002179) | 2.36541136 |
| 52 | Increased serum ferritin (HP:0003281) | 2.34364492 |
| 53 | Irregular epiphyses (HP:0010582) | 2.34118723 |
| 54 | Nonprogressive disorder (HP:0003680) | 2.28622339 |
| 55 | Abnormality involving the epiphyses of the lower limbs (HP:0006500) | 2.22329984 |
| 56 | Abnormality of femoral epiphyses (HP:0006499) | 2.22329984 |
| 57 | Muscle fiber atrophy (HP:0100295) | 2.19079797 |
| 58 | Pendular nystagmus (HP:0012043) | 2.18763261 |
| 59 | Patellar aplasia (HP:0006443) | 2.15908105 |
| 60 | Fair hair (HP:0002286) | 2.15786868 |
| 61 | Progressive cerebellar ataxia (HP:0002073) | 2.13294339 |
| 62 | Hypoplasia of the odontoid process (HP:0003311) | 2.13269200 |
| 63 | Restlessness (HP:0000711) | 2.12091035 |
| 64 | Abolished electroretinogram (ERG) (HP:0000550) | 2.08350529 |
| 65 | Epidermoid cyst (HP:0200040) | 2.08133033 |
| 66 | Hyperparathyroidism (HP:0000843) | 2.06805997 |
| 67 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.04736795 |
| 68 | Impaired proprioception (HP:0010831) | 2.04638267 |
| 69 | Enlarged epiphyses (HP:0010580) | 2.03602063 |
| 70 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 2.02785107 |
| 71 | Clumsiness (HP:0002312) | 2.02105047 |
| 72 | Progressive microcephaly (HP:0000253) | 2.01351183 |
| 73 | Furrowed tongue (HP:0000221) | 2.00906022 |
| 74 | Cystic liver disease (HP:0006706) | 2.00058654 |
| 75 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.99747819 |
| 76 | Progressive inability to walk (HP:0002505) | 1.98767830 |
| 77 | Abnormality of the neuromuscular junction (HP:0003398) | 1.98298721 |
| 78 | Fatigable weakness (HP:0003473) | 1.98298721 |
| 79 | Hemiplegia (HP:0002301) | 1.96912531 |
| 80 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.95078359 |
| 81 | Large for gestational age (HP:0001520) | 1.95055454 |
| 82 | Birth length less than 3rd percentile (HP:0003561) | 1.92554960 |
| 83 | Abnormality of ocular smooth pursuit (HP:0000617) | 1.92339048 |
| 84 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.89318910 |
| 85 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 1.89131893 |
| 86 | Hypoplasia of the fovea (HP:0007750) | 1.89131893 |
| 87 | Sclerocornea (HP:0000647) | 1.87989632 |
| 88 | Limited hip movement (HP:0008800) | 1.87921874 |
| 89 | Protruding tongue (HP:0010808) | 1.87905207 |
| 90 | Ventricular fibrillation (HP:0001663) | 1.87193953 |
| 91 | Easy fatigability (HP:0003388) | 1.86893572 |
| 92 | Hypoplasia of the brainstem (HP:0002365) | 1.86416860 |
| 93 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 1.86416860 |
| 94 | Aplasia/hypoplasia of the femur (HP:0005613) | 1.85710755 |
| 95 | Asplenia (HP:0001746) | 1.83556072 |
| 96 | Hip contracture (HP:0003273) | 1.81935508 |
| 97 | Difficulty walking (HP:0002355) | 1.81805146 |
| 98 | Autoimmune hemolytic anemia (HP:0001890) | 1.80571455 |
| 99 | Flared iliac wings (HP:0002869) | 1.80263841 |
| 100 | Scotoma (HP:0000575) | 1.79142306 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TLK1 | 7.46091452 |
| 2 | FRK | 5.68553020 |
| 3 | KDR | 3.92845975 |
| 4 | ADRBK2 | 3.25457763 |
| 5 | ZAK | 2.81704120 |
| 6 | DAPK2 | 2.80721454 |
| 7 | PNCK | 2.49854941 |
| 8 | MKNK2 | 2.21873191 |
| 9 | SIK2 | 2.07040482 |
| 10 | RIPK4 | 2.01301140 |
| 11 | MAP3K11 | 1.94458832 |
| 12 | EPHA4 | 1.93146354 |
| 13 | BLK | 1.91845767 |
| 14 | TIE1 | 1.87066513 |
| 15 | VRK2 | 1.81200166 |
| 16 | TRPM7 | 1.77752325 |
| 17 | NUAK1 | 1.63065621 |
| 18 | STK38 | 1.57376821 |
| 19 | TAF1 | 1.50297572 |
| 20 | DAPK1 | 1.48740889 |
| 21 | BMPR1B | 1.38806198 |
| 22 | SGK2 | 1.31524237 |
| 23 | PTK2B | 1.28116885 |
| 24 | TXK | 1.27519746 |
| 25 | MAP3K5 | 1.24339926 |
| 26 | LATS1 | 1.23994352 |
| 27 | FGR | 1.23764927 |
| 28 | ADRBK1 | 1.22103403 |
| 29 | INSRR | 1.19756833 |
| 30 | MAP4K1 | 1.15109042 |
| 31 | ACVR1B | 1.13806198 |
| 32 | ITK | 1.11407455 |
| 33 | MUSK | 1.06995079 |
| 34 | EIF2AK3 | 1.04477631 |
| 35 | MKNK1 | 1.02159786 |
| 36 | NEK9 | 1.01878815 |
| 37 | TGFBR1 | 0.95928918 |
| 38 | MELK | 0.90546319 |
| 39 | SGK494 | 0.87309212 |
| 40 | SGK223 | 0.87309212 |
| 41 | GRK5 | 0.85768486 |
| 42 | WNK3 | 0.83575109 |
| 43 | STK4 | 0.79290944 |
| 44 | ALK | 0.77956581 |
| 45 | NEK2 | 0.74986656 |
| 46 | ERBB3 | 0.73045923 |
| 47 | CSF1R | 0.72241791 |
| 48 | GRK1 | 0.69531304 |
| 49 | LYN | 0.67766288 |
| 50 | TNK2 | 0.65711693 |
| 51 | FES | 0.65074141 |
| 52 | ZAP70 | 0.62205662 |
| 53 | PRKCG | 0.60726974 |
| 54 | SYK | 0.60696256 |
| 55 | YES1 | 0.60235166 |
| 56 | CAMK4 | 0.60010858 |
| 57 | CAMK2A | 0.59787072 |
| 58 | FLT3 | 0.58797700 |
| 59 | CASK | 0.58382116 |
| 60 | KIT | 0.57747442 |
| 61 | DYRK3 | 0.54166765 |
| 62 | IKBKB | 0.53404653 |
| 63 | HCK | 0.51825807 |
| 64 | PRKCH | 0.51816977 |
| 65 | NTRK2 | 0.51816223 |
| 66 | IKBKE | 0.47852767 |
| 67 | SGK1 | 0.46747062 |
| 68 | CAMK1 | 0.46020375 |
| 69 | PRKCZ | 0.45604260 |
| 70 | RET | 0.42634065 |
| 71 | RPS6KB1 | 0.42595168 |
| 72 | GRK6 | 0.42227049 |
| 73 | VRK1 | 0.42013030 |
| 74 | SGK3 | 0.41708232 |
| 75 | DAPK3 | 0.41545291 |
| 76 | HIPK2 | 0.40884431 |
| 77 | TEC | 0.40086741 |
| 78 | TYK2 | 0.39202349 |
| 79 | MAPK11 | 0.37769657 |
| 80 | EIF2AK2 | 0.36998302 |
| 81 | GSK3A | 0.35764505 |
| 82 | PRKCQ | 0.33147389 |
| 83 | IGF1R | 0.32931705 |
| 84 | PDK1 | 0.31864159 |
| 85 | ABL1 | 0.31849436 |
| 86 | PRKCE | 0.30845802 |
| 87 | LCK | 0.29244178 |
| 88 | AURKA | 0.27433892 |
| 89 | PTK6 | 0.26336223 |
| 90 | DYRK2 | 0.26226662 |
| 91 | TSSK6 | 0.25582357 |
| 92 | PDK2 | 0.24761365 |
| 93 | TAOK1 | 0.24219494 |
| 94 | PKN1 | 0.23130421 |
| 95 | PLK1 | 0.21952529 |
| 96 | RPS6KA6 | 0.21623445 |
| 97 | PLK2 | 0.20948068 |
| 98 | CAMK2B | 0.20582360 |
| 99 | PRKG2 | 0.20457746 |
| 100 | SRC | 0.20325739 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Phototransduction_Homo sapiens_hsa04744 | 4.52217984 |
| 2 | Nicotine addiction_Homo sapiens_hsa05033 | 3.63720714 |
| 3 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 3.41607148 |
| 4 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 3.33455641 |
| 5 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 2.71793765 |
| 6 | Morphine addiction_Homo sapiens_hsa05032 | 2.56214051 |
| 7 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.36127807 |
| 8 | Ether lipid metabolism_Homo sapiens_hsa00565 | 2.26099972 |
| 9 | GABAergic synapse_Homo sapiens_hsa04727 | 2.23422214 |
| 10 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 2.12877790 |
| 11 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.99900053 |
| 12 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.99825648 |
| 13 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.77459694 |
| 14 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.77129253 |
| 15 | ABC transporters_Homo sapiens_hsa02010 | 1.72258184 |
| 16 | Proteasome_Homo sapiens_hsa03050 | 1.71855207 |
| 17 | Olfactory transduction_Homo sapiens_hsa04740 | 1.44467615 |
| 18 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.43990628 |
| 19 | Histidine metabolism_Homo sapiens_hsa00340 | 1.40786480 |
| 20 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.35621588 |
| 21 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.29117063 |
| 22 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.27568139 |
| 23 | Circadian entrainment_Homo sapiens_hsa04713 | 1.26417549 |
| 24 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.26275289 |
| 25 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.25546544 |
| 26 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.23361945 |
| 27 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 1.20710204 |
| 28 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.19340783 |
| 29 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.17789128 |
| 30 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.17376933 |
| 31 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.17253177 |
| 32 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.16531703 |
| 33 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.15272729 |
| 34 | Huntingtons disease_Homo sapiens_hsa05016 | 1.12555391 |
| 35 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.12523958 |
| 36 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.10041296 |
| 37 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.06046520 |
| 38 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.05107965 |
| 39 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.02669157 |
| 40 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.02491811 |
| 41 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.02014508 |
| 42 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.94296355 |
| 43 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.93979888 |
| 44 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.93213883 |
| 45 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.89650019 |
| 46 | Sulfur relay system_Homo sapiens_hsa04122 | 0.88518999 |
| 47 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.88257181 |
| 48 | RNA polymerase_Homo sapiens_hsa03020 | 0.85438953 |
| 49 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.83547017 |
| 50 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.81804411 |
| 51 | Long-term depression_Homo sapiens_hsa04730 | 0.81245649 |
| 52 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.79829149 |
| 53 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.77156474 |
| 54 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.77028013 |
| 55 | Insulin secretion_Homo sapiens_hsa04911 | 0.76120209 |
| 56 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.75979039 |
| 57 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.75950938 |
| 58 | Allograft rejection_Homo sapiens_hsa05330 | 0.75622889 |
| 59 | Retinol metabolism_Homo sapiens_hsa00830 | 0.75467132 |
| 60 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.71367572 |
| 61 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.70819541 |
| 62 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.70770862 |
| 63 | Mineral absorption_Homo sapiens_hsa04978 | 0.70754365 |
| 64 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.68826376 |
| 65 | Parkinsons disease_Homo sapiens_hsa05012 | 0.68667786 |
| 66 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.67326424 |
| 67 | Taste transduction_Homo sapiens_hsa04742 | 0.66422259 |
| 68 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.66269125 |
| 69 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.65114418 |
| 70 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.64083125 |
| 71 | Homologous recombination_Homo sapiens_hsa03440 | 0.62275004 |
| 72 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.59614148 |
| 73 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.59372745 |
| 74 | RNA degradation_Homo sapiens_hsa03018 | 0.59349650 |
| 75 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.59174107 |
| 76 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.58884932 |
| 77 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.58526381 |
| 78 | Basal transcription factors_Homo sapiens_hsa03022 | 0.55428202 |
| 79 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.55416400 |
| 80 | Alzheimers disease_Homo sapiens_hsa05010 | 0.53011673 |
| 81 | Salivary secretion_Homo sapiens_hsa04970 | 0.52670405 |
| 82 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.52332517 |
| 83 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.51607154 |
| 84 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.49404809 |
| 85 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.49043345 |
| 86 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.48931836 |
| 87 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.42818572 |
| 88 | Asthma_Homo sapiens_hsa05310 | 0.42646787 |
| 89 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.41412237 |
| 90 | Ribosome_Homo sapiens_hsa03010 | 0.40963776 |
| 91 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.40100122 |
| 92 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.39671681 |
| 93 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.34161423 |
| 94 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.33396039 |
| 95 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.32901753 |
| 96 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.32315105 |
| 97 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.31124051 |
| 98 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.29951487 |
| 99 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.27380674 |
| 100 | Shigellosis_Homo sapiens_hsa05131 | 0.26807344 |

