

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation by symbiont of host defense response (GO:0052509) | 5.53108455 |
| 2 | modulation by symbiont of host defense response (GO:0052031) | 5.53108455 |
| 3 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.53108455 |
| 4 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.53108455 |
| 5 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.53108455 |
| 6 | modulation by symbiont of host immune response (GO:0052553) | 5.53108455 |
| 7 | detection of molecule of bacterial origin (GO:0032490) | 5.29653906 |
| 8 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 5.29322544 |
| 9 | response to peptidoglycan (GO:0032494) | 5.21136584 |
| 10 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.19442942 |
| 11 | negative regulation of cell killing (GO:0031342) | 5.19442942 |
| 12 | cellular extravasation (GO:0045123) | 5.01614010 |
| 13 | detection of other organism (GO:0098543) | 4.98226307 |
| 14 | macrophage activation involved in immune response (GO:0002281) | 4.90631348 |
| 15 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.81336817 |
| 16 | negative regulation of interleukin-12 production (GO:0032695) | 4.80289450 |
| 17 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.80115043 |
| 18 | neutrophil activation involved in immune response (GO:0002283) | 4.75344286 |
| 19 | detection of external biotic stimulus (GO:0098581) | 4.56984132 |
| 20 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.47874421 |
| 21 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.45166689 |
| 22 | detection of bacterium (GO:0016045) | 4.40675750 |
| 23 | germinal center formation (GO:0002467) | 4.29330465 |
| 24 | neutrophil activation (GO:0042119) | 4.28764541 |
| 25 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.19435373 |
| 26 | detection of biotic stimulus (GO:0009595) | 4.13563621 |
| 27 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.06018759 |
| 28 | granulocyte activation (GO:0036230) | 4.03129096 |
| 29 | neutrophil mediated immunity (GO:0002446) | 4.00453945 |
| 30 | immunoglobulin mediated immune response (GO:0016064) | 3.97210411 |
| 31 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.94423729 |
| 32 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.92162221 |
| 33 | leukocyte aggregation (GO:0070486) | 3.85257281 |
| 34 | macrophage activation (GO:0042116) | 3.82188026 |
| 35 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 3.81536479 |
| 36 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.76558787 |
| 37 | leukocyte migration involved in inflammatory response (GO:0002523) | 3.73013749 |
| 38 | cellular response to type I interferon (GO:0071357) | 3.71845585 |
| 39 | type I interferon signaling pathway (GO:0060337) | 3.71845585 |
| 40 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 3.71645664 |
| 41 | response to host immune response (GO:0052572) | 3.71287326 |
| 42 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.71287326 |
| 43 | microglial cell activation (GO:0001774) | 3.69650769 |
| 44 | response to type I interferon (GO:0034340) | 3.68243223 |
| 45 | regulation of gamma-delta T cell activation (GO:0046643) | 3.65699672 |
| 46 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.65117796 |
| 47 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.65089103 |
| 48 | T-helper 1 type immune response (GO:0042088) | 3.64509305 |
| 49 | respiratory burst (GO:0045730) | 3.63583333 |
| 50 | defense response to protozoan (GO:0042832) | 3.52793988 |
| 51 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.45084294 |
| 52 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.45084294 |
| 53 | myeloid cell activation involved in immune response (GO:0002275) | 3.38957844 |
| 54 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.37437278 |
| 55 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.37195155 |
| 56 | response to host (GO:0075136) | 3.37195155 |
| 57 | response to host defenses (GO:0052200) | 3.37195155 |
| 58 | myeloid leukocyte mediated immunity (GO:0002444) | 3.36557257 |
| 59 | response to interleukin-15 (GO:0070672) | 3.35171479 |
| 60 | neutrophil chemotaxis (GO:0030593) | 3.33890574 |
| 61 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.32159961 |
| 62 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.31995110 |
| 63 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.31687474 |
| 64 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.28551303 |
| 65 | regulation of mast cell degranulation (GO:0043304) | 3.28077342 |
| 66 | positive regulation of acute inflammatory response (GO:0002675) | 3.26640362 |
| 67 | neutrophil migration (GO:1990266) | 3.25259599 |
| 68 | negative regulation of cytokine production involved in immune response (GO:0002719) | 3.24854580 |
| 69 | response to muramyl dipeptide (GO:0032495) | 3.24321802 |
| 70 | response to protozoan (GO:0001562) | 3.19561963 |
| 71 | negative regulation of T cell mediated immunity (GO:0002710) | 3.19012330 |
| 72 | positive regulation of NF-kappaB import into nucleus (GO:0042346) | 3.17288920 |
| 73 | positive regulation of interferon-alpha production (GO:0032727) | 3.17187427 |
| 74 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.17006979 |
| 75 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.15491168 |
| 76 | regulation of interferon-alpha production (GO:0032647) | 3.14876695 |
| 77 | B cell mediated immunity (GO:0019724) | 3.09857956 |
| 78 | negative regulation of interleukin-6 production (GO:0032715) | 3.05648051 |
| 79 | positive regulation of type 2 immune response (GO:0002830) | 3.05339316 |
| 80 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 3.03089664 |
| 81 | negative regulation of type 2 immune response (GO:0002829) | 3.02262258 |
| 82 | regulation of mast cell activation involved in immune response (GO:0033006) | 3.00912205 |
| 83 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 2.98481240 |
| 84 | regulation of tolerance induction (GO:0002643) | 2.97078456 |
| 85 | regulation of mast cell activation (GO:0033003) | 2.96484005 |
| 86 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 2.96114696 |
| 87 | regulation of T cell tolerance induction (GO:0002664) | 2.95246362 |
| 88 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 2.94733078 |
| 89 | positive regulation of mast cell activation (GO:0033005) | 2.94437724 |
| 90 | myeloid leukocyte activation (GO:0002274) | 2.92069937 |
| 91 | cellular response to interleukin-15 (GO:0071350) | 2.91924551 |
| 92 | regulation of type 2 immune response (GO:0002828) | 2.90040296 |
| 93 | negative regulation of alpha-beta T cell activation (GO:0046636) | 2.87728058 |
| 94 | cytokine secretion (GO:0050663) | 2.86718913 |
| 95 | positive regulation of interleukin-10 production (GO:0032733) | 2.85090211 |
| 96 | granulocyte chemotaxis (GO:0071621) | 2.85018725 |
| 97 | negative regulation of toll-like receptor signaling pathway (GO:0034122) | 2.83409364 |
| 98 | positive regulation of cellular amide metabolic process (GO:0034250) | 2.83151545 |
| 99 | regulation of leukocyte degranulation (GO:0043300) | 2.83031788 |
| 100 | regulation of toll-like receptor signaling pathway (GO:0034121) | 2.81153531 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.49264611 |
| 2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.38438104 |
| 3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.47119562 |
| 4 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.73451156 |
| 5 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.48463745 |
| 6 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.39411900 |
| 7 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.38836886 |
| 8 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.35198002 |
| 9 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.05231115 |
| 10 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.87728023 |
| 11 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.87351102 |
| 12 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.78536269 |
| 13 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.75655228 |
| 14 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.73575896 |
| 15 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.71303549 |
| 16 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.50233129 |
| 17 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.44347062 |
| 18 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.43891775 |
| 19 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.39311550 |
| 20 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.32638119 |
| 21 | SPI1_23127762_ChIP-Seq_K562_Human | 2.30452749 |
| 22 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.23233972 |
| 23 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.20999537 |
| 24 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.19447450 |
| 25 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.17427850 |
| 26 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.17369834 |
| 27 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 2.03441839 |
| 28 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 2.01230103 |
| 29 | MAF_26560356_Chip-Seq_TH1_Human | 1.98324619 |
| 30 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.97018183 |
| 31 | MYB_26560356_Chip-Seq_TH2_Human | 1.96939747 |
| 32 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.95650740 |
| 33 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.94741894 |
| 34 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.93077364 |
| 35 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.90806139 |
| 36 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.87940822 |
| 37 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.81932057 |
| 38 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.79322539 |
| 39 | UTX_26944678_Chip-Seq_JUKART_Human | 1.75366500 |
| 40 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.73672654 |
| 41 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.73539721 |
| 42 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.70681787 |
| 43 | MYB_26560356_Chip-Seq_TH1_Human | 1.67152903 |
| 44 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.61388063 |
| 45 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.53134751 |
| 46 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.51629729 |
| 47 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.44115492 |
| 48 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.43744654 |
| 49 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.43616487 |
| 50 | MYC_22102868_ChIP-Seq_BL_Human | 1.43174177 |
| 51 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.38974911 |
| 52 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.37763440 |
| 53 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.35832955 |
| 54 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.34400137 |
| 55 | MAF_26560356_Chip-Seq_TH2_Human | 1.33684142 |
| 56 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.33317833 |
| 57 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.33051273 |
| 58 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.30734601 |
| 59 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.28756975 |
| 60 | GATA3_26560356_Chip-Seq_TH2_Human | 1.28264550 |
| 61 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.25262754 |
| 62 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.24759520 |
| 63 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.24704022 |
| 64 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.22603376 |
| 65 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.21486365 |
| 66 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.21040260 |
| 67 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.20858585 |
| 68 | GATA1_22025678_ChIP-Seq_K562_Human | 1.20416204 |
| 69 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.17958236 |
| 70 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.17075726 |
| 71 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.14534231 |
| 72 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.13878162 |
| 73 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.13181494 |
| 74 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.12977475 |
| 75 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.11253243 |
| 76 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.08761019 |
| 77 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.08311553 |
| 78 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.05764834 |
| 79 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.04002534 |
| 80 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.03105533 |
| 81 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.03095415 |
| 82 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.00227521 |
| 83 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.97891132 |
| 84 | GATA1_19941826_ChIP-Seq_K562_Human | 0.97861839 |
| 85 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.96333142 |
| 86 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.92779552 |
| 87 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.92779552 |
| 88 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.92779552 |
| 89 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.92614293 |
| 90 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 0.91989349 |
| 91 | GATA2_19941826_ChIP-Seq_K562_Human | 0.85060182 |
| 92 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 0.84392647 |
| 93 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.82798160 |
| 94 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.81074290 |
| 95 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.79643191 |
| 96 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.79330036 |
| 97 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.75907045 |
| 98 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.73145292 |
| 99 | KDM2B_26808549_Chip-Seq_K562_Human | 0.70976984 |
| 100 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 0.70366234 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003724_increased_susceptibility_to | 6.45652937 |
| 2 | MP0003303_peritoneal_inflammation | 5.80942750 |
| 3 | MP0003436_decreased_susceptibility_to | 4.20089733 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.32302359 |
| 5 | MP0002419_abnormal_innate_immunity | 3.02007031 |
| 6 | MP0009785_altered_susceptibility_to | 2.90590340 |
| 7 | MP0005000_abnormal_immune_tolerance | 2.77231851 |
| 8 | MP0005025_abnormal_response_to | 2.74508624 |
| 9 | MP0009278_abnormal_bone_marrow | 2.68886483 |
| 10 | MP0002148_abnormal_hypersensitivity_rea | 2.62948998 |
| 11 | MP0001790_abnormal_immune_system | 2.62101467 |
| 12 | MP0005387_immune_system_phenotype | 2.62101467 |
| 13 | MP0006082_CNS_inflammation | 2.59288885 |
| 14 | MP0001800_abnormal_humoral_immune | 2.58220016 |
| 15 | MP0005671_abnormal_response_to | 2.43921918 |
| 16 | MP0001533_abnormal_skeleton_physiology | 2.43593898 |
| 17 | MP0000685_abnormal_immune_system | 2.41685021 |
| 18 | MP0002723_abnormal_immune_serum | 2.41571030 |
| 19 | MP0002452_abnormal_antigen_presenting | 2.31270942 |
| 20 | MP0008004_abnormal_stomach_pH | 2.27738672 |
| 21 | MP0002420_abnormal_adaptive_immunity | 2.19045381 |
| 22 | MP0001819_abnormal_immune_cell | 2.18024261 |
| 23 | MP0003300_gastrointestinal_ulcer | 2.17088440 |
| 24 | MP0009764_decreased_sensitivity_to | 2.17021451 |
| 25 | MP0003191_abnormal_cellular_cholesterol | 2.09695262 |
| 26 | MP0004947_skin_inflammation | 1.98477805 |
| 27 | MP0003075_altered_response_to | 1.92279118 |
| 28 | MP0002405_respiratory_system_inflammati | 1.85867306 |
| 29 | MP0010155_abnormal_intestine_physiology | 1.83614182 |
| 30 | MP0004510_myositis | 1.81748581 |
| 31 | MP0005451_abnormal_body_composition | 1.76876098 |
| 32 | MP0001845_abnormal_inflammatory_respons | 1.75569323 |
| 33 | MP0005464_abnormal_platelet_physiology | 1.74347763 |
| 34 | MP0002132_abnormal_respiratory_system | 1.68756424 |
| 35 | MP0002277_abnormal_respiratory_mucosa | 1.62094986 |
| 36 | MP0001545_abnormal_hematopoietic_system | 1.61411430 |
| 37 | MP0005397_hematopoietic_system_phenotyp | 1.61411430 |
| 38 | MP0003828_pulmonary_edema | 1.57288464 |
| 39 | MP0000465_gastrointestinal_hemorrhage | 1.54551691 |
| 40 | MP0000716_abnormal_immune_system | 1.54369517 |
| 41 | MP0008260_abnormal_autophagy | 1.53768539 |
| 42 | MP0002398_abnormal_bone_marrow | 1.46978021 |
| 43 | MP0008469_abnormal_protein_level | 1.45646877 |
| 44 | MP0005166_decreased_susceptibility_to | 1.45196707 |
| 45 | MP0005164_abnormal_response_to | 1.37777161 |
| 46 | MP0000858_altered_metastatic_potential | 1.30948800 |
| 47 | MP0003763_abnormal_thymus_physiology | 1.28362269 |
| 48 | MP0001853_heart_inflammation | 1.27295415 |
| 49 | MP0009333_abnormal_splenocyte_physiolog | 1.26652457 |
| 50 | MP0003172_abnormal_lysosome_physiology | 1.25508777 |
| 51 | MP0002998_abnormal_bone_remodeling | 1.22723782 |
| 52 | MP0002722_abnormal_immune_system | 1.20866478 |
| 53 | MP0000343_altered_response_to | 1.19566220 |
| 54 | MP0002429_abnormal_blood_cell | 1.18525642 |
| 55 | MP0003448_altered_tumor_morphology | 1.16796021 |
| 56 | MP0004883_abnormal_blood_vessel | 1.16485922 |
| 57 | MP0000689_abnormal_spleen_morphology | 1.15587059 |
| 58 | MP0005310_abnormal_salivary_gland | 1.14662618 |
| 59 | MP0003866_abnormal_defecation | 1.14335767 |
| 60 | MP0001851_eye_inflammation | 1.14055070 |
| 61 | MP0003045_fibrosis | 1.10288471 |
| 62 | MP0002332_abnormal_exercise_endurance | 1.10104825 |
| 63 | MP0005390_skeleton_phenotype | 1.05426569 |
| 64 | MP0005167_abnormal_blood-brain_barrier | 1.02199280 |
| 65 | MP0003690_abnormal_glial_cell | 0.97380879 |
| 66 | MP0001663_abnormal_digestive_system | 0.95620601 |
| 67 | MP0003656_abnormal_erythrocyte_physiolo | 0.94054251 |
| 68 | MP0009765_abnormal_xenobiotic_induced | 0.93223270 |
| 69 | MP0003183_abnormal_peptide_metabolism | 0.90247563 |
| 70 | MP0004381_abnormal_hair_follicle | 0.89183466 |
| 71 | MP0010352_gastrointestinal_tract_polyps | 0.88921825 |
| 72 | MP0009763_increased_sensitivity_to | 0.88640985 |
| 73 | MP0005058_abnormal_lysosome_morphology | 0.87627760 |
| 74 | MP0000703_abnormal_thymus_morphology | 0.87409078 |
| 75 | MP0003806_abnormal_nucleotide_metabolis | 0.85783831 |
| 76 | MP0000604_amyloidosis | 0.79292742 |
| 77 | MP0003453_abnormal_keratinocyte_physiol | 0.79103722 |
| 78 | MP0002138_abnormal_hepatobiliary_system | 0.77633764 |
| 79 | MP0002006_tumorigenesis | 0.76873879 |
| 80 | MP0009840_abnormal_foam_cell | 0.75818036 |
| 81 | MP0002396_abnormal_hematopoietic_system | 0.75049820 |
| 82 | MP0003221_abnormal_cardiomyocyte_apopto | 0.71317308 |
| 83 | MP0002166_altered_tumor_susceptibility | 0.69973214 |
| 84 | MP0004808_abnormal_hematopoietic_stem | 0.69810056 |
| 85 | MP0000249_abnormal_blood_vessel | 0.68128869 |
| 86 | MP0004858_abnormal_nervous_system | 0.65372067 |
| 87 | MP0008874_decreased_physiological_sensi | 0.63683541 |
| 88 | MP0002254_reproductive_system_inflammat | 0.62203709 |
| 89 | MP0003795_abnormal_bone_structure | 0.58105717 |
| 90 | MP0004484_altered_response_of | 0.57270385 |
| 91 | MP0001873_stomach_inflammation | 0.57250229 |
| 92 | MP0002933_joint_inflammation | 0.56702570 |
| 93 | MP0005535_abnormal_body_temperature | 0.54430167 |
| 94 | MP0005381_digestive/alimentary_phenotyp | 0.53058203 |
| 95 | MP0000750_abnormal_muscle_regeneration | 0.52258282 |
| 96 | MP0005319_abnormal_enzyme/_coenzyme | 0.51324526 |
| 97 | MP0006054_spinal_hemorrhage | 0.50065255 |
| 98 | MP0005023_abnormal_wound_healing | 0.48444439 |
| 99 | MP0003091_abnormal_cell_migration | 0.48165451 |
| 100 | MP0005377_hearing/vestibular/ear_phenot | 0.47787627 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Orchitis (HP:0100796) | 6.71143130 |
| 2 | Myositis (HP:0100614) | 6.48186720 |
| 3 | Retrobulbar optic neuritis (HP:0100654) | 6.38100576 |
| 4 | Optic neuritis (HP:0100653) | 6.38100576 |
| 5 | Eczematoid dermatitis (HP:0000976) | 6.20163540 |
| 6 | Recurrent bacterial skin infections (HP:0005406) | 5.66012216 |
| 7 | Abnormality of macrophages (HP:0004311) | 5.50620653 |
| 8 | Recurrent abscess formation (HP:0002722) | 5.49677405 |
| 9 | Stomatitis (HP:0010280) | 5.40996474 |
| 10 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.99196806 |
| 11 | Keratoconjunctivitis sicca (HP:0001097) | 4.73161358 |
| 12 | Recurrent gram-negative bacterial infections (HP:0005420) | 4.44958900 |
| 13 | Keratoconjunctivitis (HP:0001096) | 4.35293721 |
| 14 | Gastrointestinal infarctions (HP:0005244) | 4.26293284 |
| 15 | Mediastinal lymphadenopathy (HP:0100721) | 4.23704829 |
| 16 | Increased IgE level (HP:0003212) | 4.02358239 |
| 17 | Vasculitis (HP:0002633) | 3.85302939 |
| 18 | Meningitis (HP:0001287) | 3.81065254 |
| 19 | Chronic obstructive pulmonary disease (HP:0006510) | 3.72936484 |
| 20 | Obstructive lung disease (HP:0006536) | 3.72936484 |
| 21 | Recurrent fungal infections (HP:0002841) | 3.70429783 |
| 22 | Recurrent skin infections (HP:0001581) | 3.66291407 |
| 23 | Encephalitis (HP:0002383) | 3.60445086 |
| 24 | Urticaria (HP:0001025) | 3.56913274 |
| 25 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.52038589 |
| 26 | Gangrene (HP:0100758) | 3.49780081 |
| 27 | Hemoptysis (HP:0002105) | 3.40056654 |
| 28 | Peritonitis (HP:0002586) | 3.34641181 |
| 29 | Episodic fever (HP:0001954) | 3.34593647 |
| 30 | Spontaneous hematomas (HP:0007420) | 3.33447223 |
| 31 | Amyloidosis (HP:0011034) | 3.33006948 |
| 32 | Pulmonary infiltrates (HP:0002113) | 3.23371253 |
| 33 | Arterial thrombosis (HP:0004420) | 3.23193229 |
| 34 | Gingivitis (HP:0000230) | 3.22785243 |
| 35 | Anorexia (HP:0002039) | 3.14249877 |
| 36 | Chest pain (HP:0100749) | 3.06997098 |
| 37 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.06870518 |
| 38 | Recurrent cutaneous fungal infections (HP:0011370) | 3.06870518 |
| 39 | Leukocytosis (HP:0001974) | 2.97207560 |
| 40 | Pulmonary embolism (HP:0002204) | 2.84400098 |
| 41 | Abnormality of the pleura (HP:0002103) | 2.79628332 |
| 42 | Abnormality of the peritoneum (HP:0002585) | 2.78968779 |
| 43 | Cellulitis (HP:0100658) | 2.78311207 |
| 44 | Gingival bleeding (HP:0000225) | 2.71268360 |
| 45 | Increased IgM level (HP:0003496) | 2.67825322 |
| 46 | Abnormality of T cell number (HP:0011839) | 2.59290360 |
| 47 | T lymphocytopenia (HP:0005403) | 2.58369153 |
| 48 | Prolonged bleeding time (HP:0003010) | 2.56392059 |
| 49 | Abnormality of glycolipid metabolism (HP:0010969) | 2.51545011 |
| 50 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.51545011 |
| 51 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.51545011 |
| 52 | Recurrent viral infections (HP:0004429) | 2.44143344 |
| 53 | Segmental peripheral demyelination/remyelination (HP:0003481) | 2.43465830 |
| 54 | Hypochromic anemia (HP:0001931) | 2.41194078 |
| 55 | Abnormality of the endocardium (HP:0004306) | 2.40865465 |
| 56 | Inflammation of the large intestine (HP:0002037) | 2.40651127 |
| 57 | Hypergammaglobulinemia (HP:0010702) | 2.39597298 |
| 58 | Sepsis (HP:0100806) | 2.38759596 |
| 59 | Glomerulopathy (HP:0100820) | 2.36542414 |
| 60 | Hypochromic microcytic anemia (HP:0004840) | 2.32683422 |
| 61 | Keratitis (HP:0000491) | 2.31837689 |
| 62 | Pustule (HP:0200039) | 2.29251883 |
| 63 | Epistaxis (HP:0000421) | 2.29192732 |
| 64 | Premature loss of primary teeth (HP:0006323) | 2.29103974 |
| 65 | Vertigo (HP:0002321) | 2.28627406 |
| 66 | Gastrointestinal inflammation (HP:0004386) | 2.27141307 |
| 67 | Granulocytopenia (HP:0001913) | 2.26553073 |
| 68 | Acne (HP:0001061) | 2.23293493 |
| 69 | Osteomyelitis (HP:0002754) | 2.22390411 |
| 70 | Autoimmune thrombocytopenia (HP:0001973) | 2.22285850 |
| 71 | Systemic lupus erythematosus (HP:0002725) | 2.21940539 |
| 72 | Loss of speech (HP:0002371) | 2.20001972 |
| 73 | Abnormality of the pericardium (HP:0001697) | 2.19259048 |
| 74 | Petechiae (HP:0000967) | 2.18882626 |
| 75 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.15797695 |
| 76 | Abnormality of T cells (HP:0002843) | 2.15033088 |
| 77 | Polyneuropathy (HP:0001271) | 2.09539806 |
| 78 | Interstitial pulmonary disease (HP:0006530) | 2.07690548 |
| 79 | Eosinophilia (HP:0001880) | 2.07208558 |
| 80 | Chronic otitis media (HP:0000389) | 2.05501133 |
| 81 | Increased serum ferritin (HP:0003281) | 2.03831358 |
| 82 | Increased cerebral lipofuscin (HP:0011813) | 2.02300682 |
| 83 | Skin ulcer (HP:0200042) | 1.99764531 |
| 84 | Colitis (HP:0002583) | 1.98928399 |
| 85 | Purpura (HP:0000979) | 1.95983064 |
| 86 | Autoimmune hemolytic anemia (HP:0001890) | 1.91848250 |
| 87 | Skin rash (HP:0000988) | 1.91186692 |
| 88 | Thrombophlebitis (HP:0004418) | 1.91041389 |
| 89 | Recurrent bronchitis (HP:0002837) | 1.90981954 |
| 90 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.90378013 |
| 91 | Cheilitis (HP:0100825) | 1.88841055 |
| 92 | Disinhibition (HP:0000734) | 1.87118706 |
| 93 | Abnormality of T cell physiology (HP:0011840) | 1.86058926 |
| 94 | Slow saccadic eye movements (HP:0000514) | 1.85903931 |
| 95 | Malnutrition (HP:0004395) | 1.85075459 |
| 96 | Joint swelling (HP:0001386) | 1.84089593 |
| 97 | Abnormality of iron homeostasis (HP:0011031) | 1.84042927 |
| 98 | Arthralgia (HP:0002829) | 1.83434526 |
| 99 | Lymphopenia (HP:0001888) | 1.82873801 |
| 100 | Hepatosplenomegaly (HP:0001433) | 1.80380324 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 4.54417707 |
| 2 | IRAK4 | 3.64297194 |
| 3 | MAP4K1 | 3.55969725 |
| 4 | BLK | 3.26518370 |
| 5 | ERN1 | 3.23153499 |
| 6 | TYK2 | 2.77835899 |
| 7 | MAP2K3 | 2.64268948 |
| 8 | TXK | 2.61154060 |
| 9 | CSK | 2.58151953 |
| 10 | EPHB1 | 2.35891182 |
| 11 | ZAP70 | 2.26270400 |
| 12 | MAP3K14 | 2.15317140 |
| 13 | IRAK3 | 2.13222166 |
| 14 | TAOK1 | 2.00063942 |
| 15 | IKBKE | 1.96605977 |
| 16 | IRAK1 | 1.92763817 |
| 17 | MAP3K3 | 1.88209354 |
| 18 | FES | 1.84177475 |
| 19 | JAK3 | 1.83317309 |
| 20 | GRK6 | 1.77754397 |
| 21 | TBK1 | 1.76338996 |
| 22 | TNK2 | 1.72450028 |
| 23 | MAP3K11 | 1.72133436 |
| 24 | JAK2 | 1.71601494 |
| 25 | PRPF4B | 1.71082268 |
| 26 | FGR | 1.66577381 |
| 27 | IRAK2 | 1.66420895 |
| 28 | MAP3K1 | 1.59195334 |
| 29 | MATK | 1.58248242 |
| 30 | HCK | 1.55287017 |
| 31 | BMPR2 | 1.39956349 |
| 32 | BTK | 1.38102163 |
| 33 | SYK | 1.37780046 |
| 34 | SIK3 | 1.35594308 |
| 35 | LYN | 1.34623235 |
| 36 | TAOK3 | 1.31106137 |
| 37 | JAK1 | 1.30923004 |
| 38 | KSR2 | 1.28632775 |
| 39 | TAOK2 | 1.21757038 |
| 40 | IKBKB | 1.19609028 |
| 41 | EPHA3 | 1.18634190 |
| 42 | MAP3K13 | 1.14321060 |
| 43 | CDC42BPA | 1.01000857 |
| 44 | LCK | 0.96831530 |
| 45 | YES1 | 0.96824035 |
| 46 | KIT | 0.96613084 |
| 47 | MARK3 | 0.92336164 |
| 48 | GRK7 | 0.89014370 |
| 49 | RIPK1 | 0.82640464 |
| 50 | MARK2 | 0.81951384 |
| 51 | TGFBR2 | 0.80637338 |
| 52 | MAP3K2 | 0.78299146 |
| 53 | FGFR4 | 0.78166061 |
| 54 | CSF1R | 0.77880539 |
| 55 | MAP3K6 | 0.77578807 |
| 56 | MAP3K5 | 0.74016889 |
| 57 | PRKD2 | 0.71686590 |
| 58 | PTK6 | 0.71303577 |
| 59 | SIK2 | 0.70456633 |
| 60 | PDK1 | 0.69651235 |
| 61 | PDPK1 | 0.66830662 |
| 62 | FGFR3 | 0.64122863 |
| 63 | STK10 | 0.63823416 |
| 64 | MAPK7 | 0.63005997 |
| 65 | ITK | 0.59862197 |
| 66 | TESK2 | 0.57822584 |
| 67 | FYN | 0.57795947 |
| 68 | MAP2K4 | 0.54746943 |
| 69 | HIPK2 | 0.52459284 |
| 70 | TRIB3 | 0.51450227 |
| 71 | CHUK | 0.51132301 |
| 72 | SIK1 | 0.50386965 |
| 73 | MOS | 0.48367019 |
| 74 | MAP2K6 | 0.48346623 |
| 75 | PIK3CG | 0.47682802 |
| 76 | PRKG2 | 0.45634974 |
| 77 | DAPK2 | 0.45594020 |
| 78 | PTK2B | 0.45244301 |
| 79 | MAPK12 | 0.44996908 |
| 80 | TEC | 0.44777155 |
| 81 | CDK19 | 0.44009402 |
| 82 | NLK | 0.42833171 |
| 83 | STK11 | 0.40719490 |
| 84 | MAP3K7 | 0.40342038 |
| 85 | PIM1 | 0.39623214 |
| 86 | MAPKAPK2 | 0.39528539 |
| 87 | KSR1 | 0.38934025 |
| 88 | DYRK1B | 0.37627019 |
| 89 | LRRK2 | 0.37067329 |
| 90 | RAF1 | 0.36761258 |
| 91 | SMG1 | 0.36562995 |
| 92 | SGK3 | 0.36431520 |
| 93 | RPS6KL1 | 0.35885531 |
| 94 | RPS6KC1 | 0.35885531 |
| 95 | ACVR1B | 0.35582171 |
| 96 | RET | 0.34341164 |
| 97 | WNK1 | 0.33726629 |
| 98 | ALK | 0.32670691 |
| 99 | PRKCZ | 0.32234415 |
| 100 | STK38 | 0.30958261 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Leishmaniasis_Homo sapiens_hsa05140 | 3.17789056 |
| 2 | Osteoclast differentiation_Homo sapiens_hsa04380 | 3.11513574 |
| 3 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 3.02541099 |
| 4 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.51837292 |
| 5 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.47371819 |
| 6 | Malaria_Homo sapiens_hsa05144 | 2.31852760 |
| 7 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.25478822 |
| 8 | Tuberculosis_Homo sapiens_hsa05152 | 2.24960800 |
| 9 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.18340353 |
| 10 | Allograft rejection_Homo sapiens_hsa05330 | 2.16387111 |
| 11 | Legionellosis_Homo sapiens_hsa05134 | 2.11945962 |
| 12 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.07005981 |
| 13 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.91779364 |
| 14 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.85433211 |
| 15 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.85153660 |
| 16 | Influenza A_Homo sapiens_hsa05164 | 1.81229162 |
| 17 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.77196005 |
| 18 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.76646331 |
| 19 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.75044759 |
| 20 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.71485691 |
| 21 | Pertussis_Homo sapiens_hsa05133 | 1.71063980 |
| 22 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.70562368 |
| 23 | Measles_Homo sapiens_hsa05162 | 1.70505814 |
| 24 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.64253910 |
| 25 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.63753096 |
| 26 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.61861226 |
| 27 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.56766347 |
| 28 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.56501209 |
| 29 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.52669009 |
| 30 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.48433682 |
| 31 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.43605398 |
| 32 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.41558300 |
| 33 | Salmonella infection_Homo sapiens_hsa05132 | 1.39170633 |
| 34 | Asthma_Homo sapiens_hsa05310 | 1.36667686 |
| 35 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.34931517 |
| 36 | Hepatitis C_Homo sapiens_hsa05160 | 1.31389437 |
| 37 | Phagosome_Homo sapiens_hsa04145 | 1.30793033 |
| 38 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.28893135 |
| 39 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.27589782 |
| 40 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.26646184 |
| 41 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.24961455 |
| 42 | Viral myocarditis_Homo sapiens_hsa05416 | 1.24133165 |
| 43 | Hepatitis B_Homo sapiens_hsa05161 | 1.19664966 |
| 44 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.18782938 |
| 45 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.18433189 |
| 46 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.06178308 |
| 47 | Shigellosis_Homo sapiens_hsa05131 | 1.04772341 |
| 48 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.00636846 |
| 49 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.00308004 |
| 50 | Amoebiasis_Homo sapiens_hsa05146 | 0.98990954 |
| 51 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.94058268 |
| 52 | Other glycan degradation_Homo sapiens_hsa00511 | 0.93568601 |
| 53 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.91914950 |
| 54 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.91843558 |
| 55 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.89273956 |
| 56 | Apoptosis_Homo sapiens_hsa04210 | 0.88526616 |
| 57 | Platelet activation_Homo sapiens_hsa04611 | 0.82133685 |
| 58 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.81055650 |
| 59 | Lysosome_Homo sapiens_hsa04142 | 0.78036377 |
| 60 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.77051979 |
| 61 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.71698629 |
| 62 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.71241443 |
| 63 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.70246315 |
| 64 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.68446258 |
| 65 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.68433575 |
| 66 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.66522437 |
| 67 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.61782473 |
| 68 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.61316994 |
| 69 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.60151494 |
| 70 | Bladder cancer_Homo sapiens_hsa05219 | 0.59305128 |
| 71 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.58721895 |
| 72 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.57909808 |
| 73 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.57422241 |
| 74 | Endocytosis_Homo sapiens_hsa04144 | 0.56096556 |
| 75 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.54984268 |
| 76 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.54796038 |
| 77 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.54090782 |
| 78 | Insulin resistance_Homo sapiens_hsa04931 | 0.53061271 |
| 79 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.52385340 |
| 80 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.51297819 |
| 81 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.49017318 |
| 82 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.48879771 |
| 83 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.46930403 |
| 84 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.46111225 |
| 85 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.44406856 |
| 86 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.43671018 |
| 87 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.41535106 |
| 88 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.41362400 |
| 89 | Prion diseases_Homo sapiens_hsa05020 | 0.41069189 |
| 90 | HTLV-I infection_Homo sapiens_hsa05166 | 0.38831428 |
| 91 | Endometrial cancer_Homo sapiens_hsa05213 | 0.37624695 |
| 92 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.36888631 |
| 93 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.33940403 |
| 94 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.32593486 |
| 95 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.31366705 |
| 96 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.30590904 |
| 97 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.28761249 |
| 98 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.26299910 |
| 99 | Prostate cancer_Homo sapiens_hsa05215 | 0.25434317 |
| 100 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.23785839 |

