HCFC1R1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)7.49549612
2energy coupled proton transport, down electrochemical gradient (GO:0015985)7.20663651
3ATP synthesis coupled proton transport (GO:0015986)7.20663651
4mitochondrial electron transport, NADH to ubiquinone (GO:0006120)7.12019751
5respiratory electron transport chain (GO:0022904)6.37302828
6electron transport chain (GO:0022900)6.24880827
7negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)5.54493181
8protein maturation by protein folding (GO:0022417)4.57057120
9ATP biosynthetic process (GO:0006754)4.22568589
10hydrogen ion transmembrane transport (GO:1902600)4.18234806
11GDP-mannose metabolic process (GO:0019673)4.10956722
12sarcomere organization (GO:0045214)3.93900859
13skeletal muscle contraction (GO:0003009)3.93020611
14skeletal muscle fiber development (GO:0048741)3.86203544
15ribosomal small subunit biogenesis (GO:0042274)3.84757631
16chaperone-mediated protein transport (GO:0072321)3.71328978
17positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)3.71269227
18purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.69672164
19protein complex biogenesis (GO:0070271)3.66479322
20proton transport (GO:0015992)3.64387884
21purine nucleoside triphosphate biosynthetic process (GO:0009145)3.62406726
22hydrogen transport (GO:0006818)3.56979174
23inner mitochondrial membrane organization (GO:0007007)3.53988966
24oxidative phosphorylation (GO:0006119)3.52559927
25regulation of cell communication by electrical coupling (GO:0010649)3.51165774
26positive regulation of mitochondrial calcium ion concentration (GO:0051561)3.48672009
27muscle filament sliding (GO:0030049)3.47960880
28actin-myosin filament sliding (GO:0033275)3.47960880
29protein insertion into membrane (GO:0051205)3.47760291
30positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.46674666
31regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)3.46606546
32regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.45937038
33UV protection (GO:0009650)3.43436266
34adenine nucleotide transport (GO:0051503)3.42740356
35mitochondrial respiratory chain complex I assembly (GO:0032981)3.40826529
36NADH dehydrogenase complex assembly (GO:0010257)3.40826529
37mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.40826529
38regulation of relaxation of muscle (GO:1901077)3.38795416
39response to muscle activity (GO:0014850)3.38348738
40adenosine receptor signaling pathway (GO:0001973)3.33893153
41regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)3.33586842
42ATP hydrolysis coupled proton transport (GO:0015991)3.32657237
43energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.32657237
44synaptic vesicle docking involved in exocytosis (GO:0016081)3.29349382
45gluconeogenesis (GO:0006094)3.29148336
46negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)3.24108999
47cardiac myofibril assembly (GO:0055003)3.23130938
48myotube cell development (GO:0014904)3.18481812
49heart process (GO:0003015)3.18157170
50heart contraction (GO:0060047)3.18157170
51mitochondrial respiratory chain complex assembly (GO:0033108)3.17966756
52protein neddylation (GO:0045116)3.17579882
53ribonucleoside triphosphate biosynthetic process (GO:0009201)3.14547317
54calcium-mediated signaling using intracellular calcium source (GO:0035584)3.11627650
55neuromuscular synaptic transmission (GO:0007274)3.10692207
56myofibril assembly (GO:0030239)3.08536786
57hexose biosynthetic process (GO:0019319)3.06676934
58protein retention in ER lumen (GO:0006621)3.01490860
59regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)3.00689708
60creatine metabolic process (GO:0006600)2.99918306
61actin-mediated cell contraction (GO:0070252)2.99658422
62regulation of mitochondrial translation (GO:0070129)2.93831675
63negative regulation of protein localization to cell surface (GO:2000009)2.92022881
64cardiac muscle contraction (GO:0060048)2.91246895
65negative regulation of calcium ion transmembrane transport (GO:1903170)2.91240435
66negative regulation of calcium ion transmembrane transporter activity (GO:1901020)2.91240435
67positive regulation of synapse maturation (GO:0090129)2.90403477
68viral transcription (GO:0019083)2.89846673
69tricarboxylic acid cycle (GO:0006099)2.88957766
70monosaccharide biosynthetic process (GO:0046364)2.88774594
71nucleoside transmembrane transport (GO:1901642)2.87907833
72sarcoplasmic reticulum calcium ion transport (GO:0070296)2.82554375
73detection of calcium ion (GO:0005513)2.81289590
74regulation of oxidative phosphorylation (GO:0002082)2.79384263
75muscle fiber development (GO:0048747)2.78233399
76dopamine biosynthetic process (GO:0042416)2.77571182
77cardiac muscle tissue morphogenesis (GO:0055008)2.77316151
78negative regulation of potassium ion transmembrane transporter activity (GO:1901017)2.77163502
79metallo-sulfur cluster assembly (GO:0031163)2.75895430
80iron-sulfur cluster assembly (GO:0016226)2.75895430
81response to gravity (GO:0009629)2.75036900
82regulation of actin filament-based movement (GO:1903115)2.68849040
83nucleoside triphosphate biosynthetic process (GO:0009142)2.68742983
84establishment of protein localization to mitochondrial membrane (GO:0090151)2.66699978
85nucleotide salvage (GO:0043173)2.66662957
86ventricular cardiac muscle tissue morphogenesis (GO:0055010)2.66354028
87positive regulation of TOR signaling (GO:0032008)2.66135421
88regulation of striated muscle contraction (GO:0006942)2.64465513
89actin filament-based movement (GO:0030048)2.62362698
90translational termination (GO:0006415)2.62221521
91negative regulation of cardiac muscle cell apoptotic process (GO:0010667)2.62160306
92muscle contraction (GO:0006936)2.60985378
93glutamate secretion (GO:0014047)2.60793399
94pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.59880650
95generation of precursor metabolites and energy (GO:0006091)2.59815157
96negative regulation of cation channel activity (GO:2001258)2.57772213
97positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.56595411
98endoplasmic reticulum calcium ion homeostasis (GO:0032469)2.56307885
99mitotic nuclear envelope reassembly (GO:0007084)2.55625937
100nuclear envelope reassembly (GO:0031468)2.55625937
101glycogen catabolic process (GO:0005980)2.55348855
102plasma membrane repair (GO:0001778)2.55040175
103neuronal action potential propagation (GO:0019227)2.54907831
104ventricular cardiac muscle cell action potential (GO:0086005)2.54578695
105barbed-end actin filament capping (GO:0051016)2.54134742
106negative regulation of potassium ion transmembrane transport (GO:1901380)2.54042726
107negative regulation of striated muscle cell apoptotic process (GO:0010664)2.53498874
108muscle tissue morphogenesis (GO:0060415)2.52717305
109translational elongation (GO:0006414)2.52313807
110bundle of His cell to Purkinje myocyte communication (GO:0086069)2.51843808
111purine nucleotide transport (GO:0015865)2.51749440
112response to stimulus involved in regulation of muscle adaptation (GO:0014874)2.51739754
113maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.51622432
114NADH metabolic process (GO:0006734)2.51488455
115regulation of voltage-gated calcium channel activity (GO:1901385)2.51334460
116dopamine transport (GO:0015872)2.51317547
117oxygen transport (GO:0015671)2.50248562
118synaptic vesicle maturation (GO:0016188)2.50005709
119glycogen biosynthetic process (GO:0005978)2.49083343
120glucan biosynthetic process (GO:0009250)2.49083343
121mitochondrial calcium ion homeostasis (GO:0051560)2.49046865
122regulation of skeletal muscle contraction (GO:0014819)2.48897029
123regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.47948388
124establishment of protein localization to mitochondrion (GO:0072655)2.47344954
125purine nucleotide salvage (GO:0032261)2.46641940
126transferrin transport (GO:0033572)2.45982390
127behavioral response to cocaine (GO:0048148)2.45948364
128regulation of cardiac muscle contraction (GO:0055117)2.44145305
129regulation of membrane repolarization (GO:0060306)2.43425816
130neuron cell-cell adhesion (GO:0007158)2.43048275
131protein targeting to mitochondrion (GO:0006626)2.41866009
132adult heart development (GO:0007512)2.41578521
133cytochrome complex assembly (GO:0017004)2.40636176
134purine ribonucleotide transport (GO:0015868)2.40438320
135regulation of protein kinase A signaling (GO:0010738)2.39690289
136aerobic respiration (GO:0009060)2.38775188
137regulation of synapse structural plasticity (GO:0051823)2.38430283
138base-excision repair, AP site formation (GO:0006285)2.36644972
139synaptic vesicle exocytosis (GO:0016079)2.36493923
140ubiquinone biosynthetic process (GO:0006744)2.34750050
141phenol-containing compound catabolic process (GO:0019336)2.34354830
142viral life cycle (GO:0019058)2.33524952
143striated muscle contraction (GO:0006941)2.33502086
144deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.32880317
145regulation of dopamine metabolic process (GO:0042053)2.32443583
146regulation of catecholamine metabolic process (GO:0042069)2.32443583
147regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.32402425
148regulation of calcium ion transmembrane transport (GO:1903169)2.32104234
149regulation of calcium ion transmembrane transporter activity (GO:1901019)2.32104234
150negative regulation of ion transmembrane transporter activity (GO:0032413)2.29987149
151positive regulation of calcium ion transmembrane transporter activity (GO:1901021)2.28996829
152actomyosin structure organization (GO:0031032)2.28071156
153positive regulation of potassium ion transmembrane transport (GO:1901381)2.28027029
154regulation of acyl-CoA biosynthetic process (GO:0050812)2.27874774
155respiratory chain complex IV assembly (GO:0008535)2.27329008
156ferric iron transport (GO:0015682)2.26491967
157trivalent inorganic cation transport (GO:0072512)2.26491967
158cell communication involved in cardiac conduction (GO:0086065)2.26450467
159substantia nigra development (GO:0021762)2.26377033

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.12868546
2LXR_22292898_ChIP-Seq_THP-1_Human2.78166379
3SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.71057052
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.64351620
5* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.58525435
6SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.45718693
7* ESRRB_18555785_ChIP-Seq_MESCs_Mouse2.41578281
8JARID2_20064375_ChIP-Seq_MESCs_Mouse2.34986587
9EZH2_27304074_Chip-Seq_ESCs_Mouse2.32526064
10SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.30364564
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.29191665
12EED_16625203_ChIP-ChIP_MESCs_Mouse2.23857945
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.23014242
14TET1_21451524_ChIP-Seq_MESCs_Mouse2.22507923
15RNF2_18974828_ChIP-Seq_MESCs_Mouse2.21485084
16EZH2_18974828_ChIP-Seq_MESCs_Mouse2.21485084
17GBX2_23144817_ChIP-Seq_PC3_Human2.19900941
18P68_20966046_ChIP-Seq_HELA_Human2.18195051
19MTF2_20144788_ChIP-Seq_MESCs_Mouse2.11985664
20CDX2_19796622_ChIP-Seq_MESCs_Mouse2.09127166
21BMI1_23680149_ChIP-Seq_NPCS_Mouse2.08269781
22SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.06687032
23HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.06219110
24CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human2.04585420
25VDR_21846776_ChIP-Seq_THP-1_Human2.04409146
26JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.01269439
27EZH2_27294783_Chip-Seq_ESCs_Mouse1.98532275
28SUZ12_27294783_Chip-Seq_ESCs_Mouse1.95681414
29DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.93600154
30EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.90376255
31RACK7_27058665_Chip-Seq_MCF-7_Human1.90035434
32EP300_21415370_ChIP-Seq_HL-1_Mouse1.86802203
33TAF15_26573619_Chip-Seq_HEK293_Human1.85694719
34* THAP11_20581084_ChIP-Seq_MESCs_Mouse1.84844876
35ELK3_25401928_ChIP-Seq_HUVEC_Human1.84262175
36ZNF263_19887448_ChIP-Seq_K562_Human1.82612222
37TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.76699973
38PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.76675150
39* XRN2_22483619_ChIP-Seq_HELA_Human1.76621969
40TRIM28_21343339_ChIP-Seq_HEK293_Human1.71282164
41IKZF1_21737484_ChIP-ChIP_HCT116_Human1.65809322
42PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.65375907
43BCL6_27268052_Chip-Seq_Bcells_Human1.64589004
44* PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.62485453
45* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.61480232
46* SA1_27219007_Chip-Seq_ERYTHROID_Human1.61214196
47UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.59382938
48ELF1_20517297_ChIP-Seq_JURKAT_Human1.59043264
49* ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.58457356
50CTCF_27219007_Chip-Seq_ERYTHROID_Human1.58157968
51* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.54840776
52* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.54444164
53NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.52843486
54* FOXP1_21924763_ChIP-Seq_HESCs_Human1.52406735
55SMC4_20622854_ChIP-Seq_HELA_Human1.51936155
56* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.49927815
57BCOR_27268052_Chip-Seq_Bcells_Human1.48389616
58SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.48243687
59RNF2_27304074_Chip-Seq_ESCs_Mouse1.47177810
60RARG_19884340_ChIP-ChIP_MEFs_Mouse1.46701874
61EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.45443560
62SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.44325392
63SA1_27219007_Chip-Seq_Bcells_Human1.44113935
64MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.43177794
65BP1_19119308_ChIP-ChIP_Hs578T_Human1.42535566
66CTCF_18555785_ChIP-Seq_MESCs_Mouse1.42526258
67* ETS1_20019798_ChIP-Seq_JURKAT_Human1.42281674
68* SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.37863880
69KDM2B_26808549_Chip-Seq_SUP-B15_Human1.37246615
70CBX2_27304074_Chip-Seq_ESCs_Mouse1.37234416
71CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.37214579
72SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.36082778
73NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.35251999
74NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.34190666
75KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.33788263
76ZFP57_27257070_Chip-Seq_ESCs_Mouse1.33455874
77E2F1_20622854_ChIP-Seq_HELA_Human1.32818743
78NR3C1_23031785_ChIP-Seq_PC12_Mouse1.32664806
79REST_21632747_ChIP-Seq_MESCs_Mouse1.31586757
80PHF8_20622854_ChIP-Seq_HELA_Human1.30543220
81CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.28875170
82CTBP2_25329375_ChIP-Seq_LNCAP_Human1.28198529
83BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.28167602
84CTCF_26484167_Chip-Seq_Bcells_Mouse1.27681575
85RARA_24833708_ChIP-Seq_LIVER_Mouse1.27170978
86VDR_22108803_ChIP-Seq_LS180_Human1.25636640
87CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.25529320
88RARB_24833708_ChIP-Seq_LIVER_Mouse1.24603907
89YY1_22570637_ChIP-Seq_MALME-3M_Human1.24457797
90CTCF_21964334_Chip-Seq_Bcells_Human1.23785873
91* KDM2B_26808549_Chip-Seq_K562_Human1.23639615
92PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.23303300
93CTCF_20526341_ChIP-Seq_ESCs_Human1.23068698
94KDM2B_26808549_Chip-Seq_DND41_Human1.21030814
95* TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.19367820
96* CREB1_26743006_Chip-Seq_LNCaP_Human1.18933871
97DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.18673330
98REST_18959480_ChIP-ChIP_MESCs_Mouse1.17593131
99TP53_22127205_ChIP-Seq_IMR90_Human1.17265084
100* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.15673249
101CTBP1_25329375_ChIP-Seq_LNCAP_Human1.15172137
102TOP2B_26459242_ChIP-Seq_MCF-7_Human1.14767301
103MAF_26560356_Chip-Seq_TH2_Human1.13137449
104CTCF_21964334_ChIP-Seq_BJAB-B_Human1.12810907
105EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.12658811
106ESR2_21235772_ChIP-Seq_MCF-7_Human1.12595701
107* CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.12420827
108ERG_21242973_ChIP-ChIP_JURKAT_Human1.12061676
109TBX5_21415370_ChIP-Seq_HL-1_Mouse1.11974864
110* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.11822511
111ATF3_27146783_Chip-Seq_COLON_Human1.11456587
112NRF2_20460467_ChIP-Seq_MEFs_Mouse1.11165274
113NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.11165274
114PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.10984475
115GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10488360
116DCP1A_22483619_ChIP-Seq_HELA_Human1.09578676
117TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.09427955
118GABP_19822575_ChIP-Seq_HepG2_Human1.09186623
119YY1_21170310_ChIP-Seq_MESCs_Mouse1.09175211
120P300_19829295_ChIP-Seq_ESCs_Human1.08845870
121RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.08408395
122PU.1_20513432_ChIP-Seq_Bcells_Mouse1.07604198
123SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.06398824
124PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.06048683
125MYC_18555785_ChIP-Seq_MESCs_Mouse1.05849628
126FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.03807602
127OCT4_18692474_ChIP-Seq_MEFs_Mouse1.03188688
128ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.02504460
129STAT3_19079543_ChIP-ChIP_MESCs_Mouse1.01992726
130SRF_21415370_ChIP-Seq_HL-1_Mouse1.01727037
131ETS1_21867929_ChIP-Seq_TH2_Mouse1.00787295
132THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.00680458
133CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.00189608
134* TET1_21490601_ChIP-Seq_MESCs_Mouse0.99888366
135* E2F1_18555785_ChIP-Seq_MESCs_Mouse0.99723350
136PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.99094497
137* TP53_20018659_ChIP-ChIP_R1E_Mouse0.98451795
138AR_21572438_ChIP-Seq_LNCaP_Human0.98079756
139UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.97470774
140TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.95955756
141CTCF_27219007_Chip-Seq_Bcells_Human0.95913629
142SMAD4_21799915_ChIP-Seq_A2780_Human0.95616334
143SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.94253636
144RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.93164364
145SRY_22984422_ChIP-ChIP_TESTIS_Rat0.91901907
146SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.91301962
147MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.91079834
148DROSHA_22980978_ChIP-Seq_HELA_Human0.90322141
149RING1B_27294783_Chip-Seq_ESCs_Mouse0.87382796
150ESR1_20079471_ChIP-ChIP_T-47D_Human0.85350647
151SOX2_20726797_ChIP-Seq_SW620_Human0.85316783
152TP53_18474530_ChIP-ChIP_U2OS_Human0.84444937
153PIAS1_25552417_ChIP-Seq_VCAP_Human0.83169855
154RAD21_21589869_ChIP-Seq_MESCs_Mouse0.81381622
155RNF2_27304074_Chip-Seq_NSC_Mouse0.80915883
156SMC3_22415368_ChIP-Seq_MEFs_Mouse0.79709178
157CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.79490797
158SMAD3_21741376_ChIP-Seq_EPCs_Human0.78487389
159ER_23166858_ChIP-Seq_MCF-7_Human0.78193137
160DNAJC2_21179169_ChIP-ChIP_NT2_Human0.77164983
161BCAT_22108803_ChIP-Seq_LS180_Human0.77030736
162SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.76785401
163LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.76104508
164PRDM14_20953172_ChIP-Seq_ESCs_Human0.73430173
165TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.73099318
166ZNF274_21170338_ChIP-Seq_K562_Hela0.73070788
167ETV2_25802403_ChIP-Seq_MESCs_Mouse0.72995641
168SOX2_19829295_ChIP-Seq_ESCs_Human0.72305637
169NANOG_19829295_ChIP-Seq_ESCs_Human0.72305637
170NANOG_20526341_ChIP-Seq_ESCs_Human0.72211144
171POU3F2_20337985_ChIP-ChIP_501MEL_Human0.72082307
172OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.70578789
173OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.69978091
174MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.69441819
175ELK1_22589737_ChIP-Seq_MCF10A_Human0.69389154
176STAT1_20625510_ChIP-Seq_HELA_Human0.69229123
177TBX20_22328084_ChIP-Seq_HEART_Mouse0.69169382
178TBX20_22080862_ChIP-Seq_HEART_Mouse0.69169382
179SA1_22415368_ChIP-Seq_MEFs_Mouse0.68838450

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002837_dystrophic_cardiac_calcinosis5.62703554
2MP0000751_myopathy3.41490195
3MP0003646_muscle_fatigue3.00568053
4MP0004084_abnormal_cardiac_muscle3.00126358
5MP0000749_muscle_degeneration2.87970330
6MP0004036_abnormal_muscle_relaxation2.81794385
7MP0003880_abnormal_central_pattern2.77882768
8MP0004215_abnormal_myocardial_fiber2.64415850
9MP0006276_abnormal_autonomic_nervous2.54041809
10MP0010030_abnormal_orbit_morphology2.50284094
11MP0003123_paternal_imprinting2.48379049
12MP0002822_catalepsy2.38647011
13MP0001529_abnormal_vocalization2.29529513
14MP0005058_abnormal_lysosome_morphology2.20770714
15MP0001905_abnormal_dopamine_level2.15055198
16MP0005330_cardiomyopathy2.06983136
17MP0002972_abnormal_cardiac_muscle2.06408683
18MP0004233_abnormal_muscle_weight2.01884083
19MP0003137_abnormal_impulse_conducting1.96572131
20MP0001968_abnormal_touch/_nociception1.94782296
21MP0003136_yellow_coat_color1.86544378
22MP0002736_abnormal_nociception_after1.85066002
23MP0004145_abnormal_muscle_electrophysio1.84575136
24MP0005620_abnormal_muscle_contractility1.77359896
25MP0004484_altered_response_of1.72608514
26MP0002735_abnormal_chemical_nociception1.68859424
27MP0004085_abnormal_heartbeat1.68136601
28MP0009379_abnormal_foot_pigmentation1.67441369
29MP0002734_abnormal_mechanical_nocicepti1.66198188
30MP0010386_abnormal_urinary_bladder1.65630696
31MP0002272_abnormal_nervous_system1.64167087
32MP0009745_abnormal_behavioral_response1.63448070
33MP0003329_amyloid_beta_deposits1.63218076
34MP0002064_seizures1.61700909
35MP0006036_abnormal_mitochondrial_physio1.60144375
36MP0001970_abnormal_pain_threshold1.58299609
37MP0003635_abnormal_synaptic_transmissio1.58032794
38MP0001984_abnormal_olfaction1.57253351
39MP0001440_abnormal_grooming_behavior1.55678868
40MP0002733_abnormal_thermal_nociception1.55312259
41MP0004270_analgesia1.53846816
42MP0009840_abnormal_foam_cell1.52921037
43MP0008775_abnormal_heart_ventricle1.51376842
44MP0009046_muscle_twitch1.51201889
45MP0004859_abnormal_synaptic_plasticity1.46554002
46MP0002106_abnormal_muscle_physiology1.45329674
47MP0005083_abnormal_biliary_tract1.42555328
48MP0003705_abnormal_hypodermis_morpholog1.41306215
49MP0001544_abnormal_cardiovascular_syste1.40735081
50MP0005385_cardiovascular_system_phenoty1.40735081
51MP0000750_abnormal_muscle_regeneration1.39913078
52MP0005257_abnormal_intraocular_pressure1.37940423
53MP0003806_abnormal_nucleotide_metabolis1.37279967
54MP0002638_abnormal_pupillary_reflex1.36869913
55MP0004087_abnormal_muscle_fiber1.34301469
56MP0006138_congestive_heart_failure1.33637259
57MP0002572_abnormal_emotion/affect_behav1.33475138
58MP0005171_absent_coat_pigmentation1.31214324
59MP0005451_abnormal_body_composition1.29224106
60MP0001501_abnormal_sleep_pattern1.29061528
61MP0005369_muscle_phenotype1.26802336
62MP0000003_abnormal_adipose_tissue1.25232356
63MP0000013_abnormal_adipose_tissue1.24697965
64MP0003122_maternal_imprinting1.23277425
65MP0002063_abnormal_learning/memory/cond1.21977095
66MP0004924_abnormal_behavior1.21276441
67MP0005386_behavior/neurological_phenoty1.21276441
68MP0000733_abnormal_muscle_development1.20284209
69MP0000230_abnormal_systemic_arterial1.17120562
70MP0002909_abnormal_adrenal_gland1.16657873
71MP0004142_abnormal_muscle_tone1.15584099
72MP0002332_abnormal_exercise_endurance1.14811776
73MP0002067_abnormal_sensory_capabilities1.14288574
74MP0004858_abnormal_nervous_system1.13770143
75MP0002127_abnormal_cardiovascular_syste1.12651679
76MP0000759_abnormal_skeletal_muscle1.11935078
77MP0003879_abnormal_hair_cell1.11725172
78MP0004510_myositis1.10663711
79MP0000747_muscle_weakness1.10203061
80MP0001502_abnormal_circadian_rhythm1.09624118
81MP0000343_altered_response_to1.06386618
82MP0002184_abnormal_innervation1.05068428
83MP0003186_abnormal_redox_activity1.05019776
84MP0000372_irregular_coat_pigmentation1.04461512
85MP0001188_hyperpigmentation1.03825978
86MP0001756_abnormal_urination1.00247486
87MP0001486_abnormal_startle_reflex1.00195155
88MP0006035_abnormal_mitochondrial_morpho0.98594878
89MP0005645_abnormal_hypothalamus_physiol0.93859446
90MP0004130_abnormal_muscle_cell0.92258082
91MP0005423_abnormal_somatic_nervous0.92108825
92MP0004043_abnormal_pH_regulation0.91176876
93MP0005165_increased_susceptibility_to0.90313519
94MP0008569_lethality_at_weaning0.87863335
95MP0005535_abnormal_body_temperature0.87652353
96MP0002653_abnormal_ependyma_morphology0.87265327
97MP0005584_abnormal_enzyme/coenzyme_acti0.86413092
98MP0001664_abnormal_digestion0.86153308
99MP0004272_abnormal_basement_membrane0.85967372
100MP0003828_pulmonary_edema0.85137977
101MP0005409_darkened_coat_color0.85060127
102MP0002876_abnormal_thyroid_physiology0.84756046
103MP0002295_abnormal_pulmonary_circulatio0.84461176
104MP0002557_abnormal_social/conspecific_i0.84432979
105MP0002163_abnormal_gland_morphology0.83570506
106MP0001299_abnormal_eye_distance/0.83517887
107MP0005375_adipose_tissue_phenotype0.83123249
108MP0001986_abnormal_taste_sensitivity0.83027346
109MP0000538_abnormal_urinary_bladder0.82514961
110MP0008260_abnormal_autophagy0.82140722
111MP0001542_abnormal_bone_strength0.82119137
112MP0005623_abnormal_meninges_morphology0.81696631
113MP0002269_muscular_atrophy0.79986345
114MP0008789_abnormal_olfactory_epithelium0.79680709
115MP0005084_abnormal_gallbladder_morpholo0.78057933
116MP0005503_abnormal_tendon_morphology0.75077471
117MP0003279_aneurysm0.74861906
118MP0000358_abnormal_cell_content/0.73391201
119MP0003950_abnormal_plasma_membrane0.73352500
120MP0004185_abnormal_adipocyte_glucose0.73219113
121MP0002066_abnormal_motor_capabilities/c0.73195393
122MP0004811_abnormal_neuron_physiology0.72050003
123MP0005174_abnormal_tail_pigmentation0.71800094
124MP0005595_abnormal_vascular_smooth0.71090443
125MP0009780_abnormal_chondrocyte_physiolo0.70825738
126MP0008874_decreased_physiological_sensi0.70685024
127MP0001661_extended_life_span0.70177574
128MP0010630_abnormal_cardiac_muscle0.69731351
129MP0003075_altered_response_to0.68321106
130MP0005646_abnormal_pituitary_gland0.67753192
131MP0005332_abnormal_amino_acid0.67285476
132MP0005275_abnormal_skin_tensile0.66238591
133MP0000778_abnormal_nervous_system0.65775730
134MP0002882_abnormal_neuron_morphology0.65597427
135MP0005670_abnormal_white_adipose0.63514590
136MP0002108_abnormal_muscle_morphology0.61465522
137MP0005501_abnormal_skin_physiology0.60907527
138MP0000604_amyloidosis0.59911844
139MP0000955_abnormal_spinal_cord0.59378752

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)6.60524284
2Nemaline bodies (HP:0003798)6.27615244
3Muscle fiber inclusion bodies (HP:0100299)6.24005526
4Abnormal mitochondria in muscle tissue (HP:0008316)6.02051092
5Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)6.01543487
6Progressive macrocephaly (HP:0004481)5.55030381
7Mitochondrial inheritance (HP:0001427)5.40811191
8Acute encephalopathy (HP:0006846)5.27502951
9Type 1 muscle fiber predominance (HP:0003803)5.16914150
10Myopathic facies (HP:0002058)5.00027934
11Sudden death (HP:0001699)4.60508929
12Increased CSF lactate (HP:0002490)4.47297666
13Hepatocellular necrosis (HP:0001404)4.43185648
14Hepatic necrosis (HP:0002605)4.02095397
15Calf muscle hypertrophy (HP:0008981)4.00186584
16Ulnar deviation of the wrist (HP:0003049)3.91149660
17Muscle hypertrophy of the lower extremities (HP:0008968)3.86991419
18Cerebral edema (HP:0002181)3.68288704
19Increased hepatocellular lipid droplets (HP:0006565)3.58766495
20Exercise intolerance (HP:0003546)3.50376528
21Lipid accumulation in hepatocytes (HP:0006561)3.46049698
22Ventricular tachycardia (HP:0004756)3.45181945
23Round ear (HP:0100830)3.43040088
24Hypothermia (HP:0002045)3.40843724
25Respiratory failure (HP:0002878)3.39057795
26Myokymia (HP:0002411)3.38177506
27Optic disc pallor (HP:0000543)3.32874927
28Exercise-induced myalgia (HP:0003738)3.29955509
29Abnormality of the calf musculature (HP:0001430)3.28713130
30Renal Fanconi syndrome (HP:0001994)3.25965170
31Centrally nucleated skeletal muscle fibers (HP:0003687)3.25860075
32Testicular atrophy (HP:0000029)3.23073580
33Pheochromocytoma (HP:0002666)3.23035578
34Distal arthrogryposis (HP:0005684)3.22693823
35Palpitations (HP:0001962)3.21175113
36Myotonia (HP:0002486)3.20662522
37Atrial fibrillation (HP:0005110)3.16926253
38Lactic acidosis (HP:0003128)3.13694350
39Neuroendocrine neoplasm (HP:0100634)3.12505842
40Increased intramyocellular lipid droplets (HP:0012240)3.11249850
41Muscle fiber splitting (HP:0003555)3.09449125
42Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.07040752
43Primary atrial arrhythmia (HP:0001692)3.06855340
44Exercise-induced muscle cramps (HP:0003710)3.05884279
45Supraventricular tachycardia (HP:0004755)2.99662594
46Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.99289027
47Decreased activity of mitochondrial respiratory chain (HP:0008972)2.99289027
48Fetal akinesia sequence (HP:0001989)2.97933800
49Syncope (HP:0001279)2.97361942
50Increased muscle lipid content (HP:0009058)2.97174306
51Increased connective tissue (HP:0009025)2.94695673
52Leukodystrophy (HP:0002415)2.94475675
53Supraventricular arrhythmia (HP:0005115)2.90989277
54Lipoatrophy (HP:0100578)2.90030569
55Abnormality of skeletal muscle fiber size (HP:0012084)2.80182590
56Calcaneovalgus deformity (HP:0001848)2.78925363
57Prolonged QT interval (HP:0001657)2.77028007
58Progressive muscle weakness (HP:0003323)2.73430883
59Rib fusion (HP:0000902)2.69949357
60Focal motor seizures (HP:0011153)2.67097697
61Hyporeflexia of lower limbs (HP:0002600)2.66966169
62Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.66827016
63EMG: myopathic abnormalities (HP:0003458)2.63088535
64Right ventricular cardiomyopathy (HP:0011663)2.60516359
65Achilles tendon contracture (HP:0001771)2.60007445
66Limb dystonia (HP:0002451)2.58457622
67Distal lower limb amyotrophy (HP:0008944)2.58303230
68Abnormality of glycolysis (HP:0004366)2.57727087
69Increased serum pyruvate (HP:0003542)2.57727087
703-Methylglutaconic aciduria (HP:0003535)2.55394669
71Bulbar palsy (HP:0001283)2.54591329
72Deformed tarsal bones (HP:0008119)2.50287234
73Difficulty climbing stairs (HP:0003551)2.49349934
74Akinesia (HP:0002304)2.49124713
75X-linked dominant inheritance (HP:0001423)2.45401624
76Vertebral compression fractures (HP:0002953)2.44894878
77Ragged-red muscle fibers (HP:0003200)2.41055083
78Dilated cardiomyopathy (HP:0001644)2.34857886
79Spinal rigidity (HP:0003306)2.34323965
80Increased serum lactate (HP:0002151)2.33099675
81Muscle stiffness (HP:0003552)2.32771196
82Muscle fiber atrophy (HP:0100295)2.32440529
83Turricephaly (HP:0000262)2.31075015
84Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.26127327
85Abnormality of renal resorption (HP:0011038)2.25489459
86Myoglobinuria (HP:0002913)2.24795402
87Left ventricular hypertrophy (HP:0001712)2.23709825
88Abnormality of the Achilles tendon (HP:0005109)2.22028631
89Exertional dyspnea (HP:0002875)2.16807152
90Axonal loss (HP:0003447)2.16785376
91Ventricular arrhythmia (HP:0004308)2.16501128
92Mildly elevated creatine phosphokinase (HP:0008180)2.14572447
93Abnormal EKG (HP:0003115)2.14356171
94Conjunctival hamartoma (HP:0100780)2.13888394
95Malignant hyperthermia (HP:0002047)2.13720722
96Ventricular fibrillation (HP:0001663)2.12318488
97Joint stiffness (HP:0001387)2.11719705
98Annular pancreas (HP:0001734)2.11440519
99Respiratory insufficiency due to muscle weakness (HP:0002747)2.06298448
100Abnormality of the left ventricular outflow tract (HP:0011103)2.03392971
101Subaortic stenosis (HP:0001682)2.03392971
102Abnormal pupillary function (HP:0007686)2.02770837
103Abnormality of liposaccharide metabolism (HP:0010968)2.01486477
104Abnormality of glycosphingolipid metabolism (HP:0004343)2.01486477
105Abnormality of glycolipid metabolism (HP:0010969)2.01486477
106Rimmed vacuoles (HP:0003805)2.00860103
107Abnormal atrioventricular conduction (HP:0005150)1.98962569
108Generalized muscle weakness (HP:0003324)1.96697804
109Foot dorsiflexor weakness (HP:0009027)1.96479478
110Lower limb amyotrophy (HP:0007210)1.95395410
111Nuclear cataract (HP:0100018)1.94515708
112Tinnitus (HP:0000360)1.93932653
113Type 2 muscle fiber atrophy (HP:0003554)1.93693469
114Respiratory difficulties (HP:0002880)1.91657709
115Cerebral hemorrhage (HP:0001342)1.91452468
116Weak cry (HP:0001612)1.90710671
117Upper limb amyotrophy (HP:0009129)1.89038711
118Distal upper limb amyotrophy (HP:0007149)1.89038711
119Atonic seizures (HP:0010819)1.88212208
120Parakeratosis (HP:0001036)1.86819400
121Bradycardia (HP:0001662)1.86752844
122Abnormality of the foot musculature (HP:0001436)1.86430771
123Cerebral hypomyelination (HP:0006808)1.85941470
124Asymmetric septal hypertrophy (HP:0001670)1.85900024
125Abnormality of the vocal cords (HP:0008777)1.85366294
126Rhabdomyolysis (HP:0003201)1.85354087
127Amniotic constriction ring (HP:0009775)1.83719378
128Abnormality of placental membranes (HP:0011409)1.83719378
129Limb-girdle muscle atrophy (HP:0003797)1.83403315
130Generalized amyotrophy (HP:0003700)1.81987090
131Neck muscle weakness (HP:0000467)1.81743926
132Double outlet right ventricle (HP:0001719)1.81711370
133Congenital malformation of the right heart (HP:0011723)1.81711370
134Hypoplastic left heart (HP:0004383)1.81398871
135Glycosuria (HP:0003076)1.81247231
136Abnormality of urine glucose concentration (HP:0011016)1.81247231
137Anxiety (HP:0000739)1.81024341
138Esophageal neoplasm (HP:0100751)1.79942857
139Neoplasm of head and neck (HP:0012288)1.79942857
140Increased variability in muscle fiber diameter (HP:0003557)1.78623364
141Supranuclear gaze palsy (HP:0000605)1.77792492
142Scapular winging (HP:0003691)1.76441152
143Lethargy (HP:0001254)1.75508877
144Visual hallucinations (HP:0002367)1.75429583
145Distal lower limb muscle weakness (HP:0009053)1.75361164
146Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.74876689
147Oligomenorrhea (HP:0000876)1.74543483
148Popliteal pterygium (HP:0009756)1.72457727
149Emotional lability (HP:0000712)1.72285026
150Absent phalangeal crease (HP:0006109)1.70809128
151Fatigable weakness (HP:0003473)1.70650530
152Abnormality of the neuromuscular junction (HP:0003398)1.70650530
153Palmoplantar keratoderma (HP:0000982)1.68142393
154Stridor (HP:0010307)1.67781524
155Heart block (HP:0012722)1.67515559
156Failure to thrive in infancy (HP:0001531)1.66830890
157Polyphagia (HP:0002591)1.64747444
158Retinal dysplasia (HP:0007973)1.64378682
159Bundle branch block (HP:0011710)1.62461878
160CNS demyelination (HP:0007305)1.60195911

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MYLK4.00690067
2MAP3K123.41595796
3TESK22.93264272
4OBSCN2.88650674
5NME12.80429493
6ARAF2.64627233
7GRK52.45945609
8GRK72.38872081
9PHKG12.34203495
10PHKG22.34203495
11VRK22.26856766
12MUSK2.09611345
13CASK2.08969510
14WNK42.07590834
15EPHA22.06968073
16LIMK12.05648217
17CAMKK21.88042888
18PIK3CA1.86069979
19NME21.75060673
20LMTK21.74593857
21CAMK2D1.64039461
22STK241.59515989
23TAOK21.53595067
24PRKD31.51893584
25STK391.51307625
26MAP2K71.45937745
27SIK11.45408818
28MAPKAPK51.45229705
29ERN11.40982698
30IRAK31.37816446
31DAPK31.37647399
32TTN1.36977396
33PIM21.30179189
34NTRK11.28826183
35TRIB31.27956952
36PAK31.27839168
37BMPR21.25850542
38MAP3K41.24186650
39EPHB21.23856276
40NTRK31.22742445
41ILK1.17371618
42CAMK2A1.15942853
43PAK61.14761053
44DAPK11.11869211
45CAMK2B1.10459005
46PTK2B1.09315460
47PRKCE1.09202467
48OXSR11.07608352
49CAMK2G1.06722898
50ADRBK11.05580243
51PLK21.05235852
52BCR1.03881477
53MAP2K31.00340460
54TESK11.00331357
55MAPK130.99025430
56SIK30.98452123
57MST40.95839424
58TNIK0.94995079
59RIPK40.94828200
60MINK10.93977503
61CDK11A0.91985554
62MAP3K90.91199934
63ADRBK20.90595647
64PDK40.90592140
65PDK30.90592140
66BCKDK0.89659432
67CDK190.88187038
68CDK150.87244819
69AURKA0.85587556
70MAP2K40.84448843
71UHMK10.83847482
72PAK40.81419910
73PTK20.81071659
74PDK20.80936026
75CAMK10.80453509
76PAK10.80426862
77CDK180.80046855
78ROCK10.78707909
79PINK10.78236245
80BRAF0.77493449
81PKN10.77422949
82MAPK150.77207818
83ROCK20.76184516
84PRKD20.75226984
85MARK10.74691070
86STK160.74214651
87SIK20.69841831
88ABL20.68139512
89MAP2K10.68014238
90DYRK1B0.67992809
91MAPK120.67806365
92MAP2K60.67738456
93WNK30.67601013
94AKT20.66680581
95DAPK20.66528724
96CDC42BPA0.65528054
97BMX0.64517302
98WNK10.64099445
99PRKACA0.63764495
100BMPR1B0.63367839
101FER0.63168790
102TIE10.62676771
103STK38L0.60798613
104DYRK20.57541619
105EPHB10.57334959
106TLK10.57063808
107EPHA40.56771861
108ICK0.56525813
109KSR20.55361221
110TRPM70.55224384
111PRKD10.54536593
112MAPKAPK30.54371537
113MARK20.53502231
114MOS0.52660793
115CDK50.51379963
116PIK3CG0.51304101
117PRKG20.51274304
118MAP2K20.50681461
119TBK10.50372303
120LRRK20.47323406
121CSNK1G30.46189157
122PRPF4B0.46178898
123MST1R0.46003592
124PRKCG0.45944269
125MAP3K110.44842866
126BRSK10.44755930
127IRAK20.43597492
128MAP3K10.43201519
129DMPK0.42966552
130LATS20.42107197
131CCNB10.41169568
132CDK140.40264734
133SGK2230.38714299
134SGK4940.38714299
135RPS6KA20.38690199
136PDPK10.38490277
137MAP3K20.35770286
138KDR0.35758383
139CSNK1G20.35099938
140CAMKK10.31020972
141RIPK10.29590389

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001906.10624217
2Parkinsons disease_Homo sapiens_hsa050125.24551289
3Sulfur relay system_Homo sapiens_hsa041224.32945282
4Alzheimers disease_Homo sapiens_hsa050104.04591838
5Cardiac muscle contraction_Homo sapiens_hsa042603.74914958
6Huntingtons disease_Homo sapiens_hsa050163.51652629
7Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049323.30064478
8Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006042.55684913
9Collecting duct acid secretion_Homo sapiens_hsa049662.43573703
10Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.38532654
11Pentose phosphate pathway_Homo sapiens_hsa000301.93869441
12Synaptic vesicle cycle_Homo sapiens_hsa047211.83789247
13Biosynthesis of amino acids_Homo sapiens_hsa012301.76481610
14Vibrio cholerae infection_Homo sapiens_hsa051101.70209851
15Galactose metabolism_Homo sapiens_hsa000521.58782996
16Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.57255657
17Sulfur metabolism_Homo sapiens_hsa009201.56540062
18Dilated cardiomyopathy_Homo sapiens_hsa054141.55648549
19Ribosome_Homo sapiens_hsa030101.55089389
20Protein export_Homo sapiens_hsa030601.53818258
21Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.50695779
22Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.48859842
23Fatty acid elongation_Homo sapiens_hsa000621.45269737
24Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.36813710
25Proteasome_Homo sapiens_hsa030501.35127822
26Glycosaminoglycan degradation_Homo sapiens_hsa005311.34500265
27Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.30447419
28Folate biosynthesis_Homo sapiens_hsa007901.30365299
29Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.25302366
30Phenylalanine metabolism_Homo sapiens_hsa003601.23485298
31Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.22363279
32Pyruvate metabolism_Homo sapiens_hsa006201.18654536
33Rheumatoid arthritis_Homo sapiens_hsa053231.17185568
34Serotonergic synapse_Homo sapiens_hsa047261.16742763
35Other glycan degradation_Homo sapiens_hsa005111.13590041
36Nicotine addiction_Homo sapiens_hsa050331.13359633
37Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.12911396
38Olfactory transduction_Homo sapiens_hsa047401.11160298
39Taste transduction_Homo sapiens_hsa047421.10345386
40Lysosome_Homo sapiens_hsa041421.04761452
41Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.02779257
42Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.02071157
43Circadian entrainment_Homo sapiens_hsa047131.01869464
44Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.01786231
45Propanoate metabolism_Homo sapiens_hsa006401.01447027
46Tyrosine metabolism_Homo sapiens_hsa003501.01041145
47SNARE interactions in vesicular transport_Homo sapiens_hsa041300.99978748
48GABAergic synapse_Homo sapiens_hsa047270.99761681
49Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.97607882
50Pyrimidine metabolism_Homo sapiens_hsa002400.95366365
51Dopaminergic synapse_Homo sapiens_hsa047280.92292658
522-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.91612425
53Amphetamine addiction_Homo sapiens_hsa050310.89213783
54Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.87330706
55Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.87168026
56Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.86542342
57Insulin secretion_Homo sapiens_hsa049110.86133879
58Morphine addiction_Homo sapiens_hsa050320.83656078
59Cocaine addiction_Homo sapiens_hsa050300.82203854
60Cholinergic synapse_Homo sapiens_hsa047250.81568859
61Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.80346435
62Calcium signaling pathway_Homo sapiens_hsa040200.76991432
63Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.75474499
64Arginine biosynthesis_Homo sapiens_hsa002200.74773514
65Butanoate metabolism_Homo sapiens_hsa006500.73807977
66Phagosome_Homo sapiens_hsa041450.71237073
67Glutamatergic synapse_Homo sapiens_hsa047240.71030438
68Vascular smooth muscle contraction_Homo sapiens_hsa042700.69264813
69Insulin signaling pathway_Homo sapiens_hsa049100.69067418
70Renin secretion_Homo sapiens_hsa049240.67408079
71Salivary secretion_Homo sapiens_hsa049700.66503096
72Base excision repair_Homo sapiens_hsa034100.66422710
73Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.64318726
74Circadian rhythm_Homo sapiens_hsa047100.60888516
75Arachidonic acid metabolism_Homo sapiens_hsa005900.60815555
76Gastric acid secretion_Homo sapiens_hsa049710.60812278
77Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.59125548
78Prion diseases_Homo sapiens_hsa050200.57369325
79Vitamin B6 metabolism_Homo sapiens_hsa007500.56847979
80Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.56436775
81Endocytosis_Homo sapiens_hsa041440.56046692
82Purine metabolism_Homo sapiens_hsa002300.55712883
83Metabolic pathways_Homo sapiens_hsa011000.55117248
84Carbon metabolism_Homo sapiens_hsa012000.54614960
85Histidine metabolism_Homo sapiens_hsa003400.53952817
86Linoleic acid metabolism_Homo sapiens_hsa005910.53711319
87Oxytocin signaling pathway_Homo sapiens_hsa049210.52322728
88Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.51974854
89Aldosterone synthesis and secretion_Homo sapiens_hsa049250.51823293
90Long-term depression_Homo sapiens_hsa047300.51445698
91Ether lipid metabolism_Homo sapiens_hsa005650.48583802
92Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.47825071
93Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.46861341
94Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.46440265
95AMPK signaling pathway_Homo sapiens_hsa041520.45851457
96VEGF signaling pathway_Homo sapiens_hsa043700.44176092
97Bladder cancer_Homo sapiens_hsa052190.44045404
98cGMP-PKG signaling pathway_Homo sapiens_hsa040220.43466121
99Pancreatic secretion_Homo sapiens_hsa049720.43320360
100alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.43018596
101Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.42492216
102Regulation of autophagy_Homo sapiens_hsa041400.41753978
103Long-term potentiation_Homo sapiens_hsa047200.39736184
104Phototransduction_Homo sapiens_hsa047440.39366181
105Fatty acid metabolism_Homo sapiens_hsa012120.38813531
106Salmonella infection_Homo sapiens_hsa051320.38000274
107Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.37281539
108Cyanoamino acid metabolism_Homo sapiens_hsa004600.36448615
109Hedgehog signaling pathway_Homo sapiens_hsa043400.36083548
110Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.35600085
111Cysteine and methionine metabolism_Homo sapiens_hsa002700.35453808
112RNA polymerase_Homo sapiens_hsa030200.35426020
113Hippo signaling pathway_Homo sapiens_hsa043900.35058771
114GnRH signaling pathway_Homo sapiens_hsa049120.34595990
115Gap junction_Homo sapiens_hsa045400.33938524
116Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.33425576
117Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.32475799
118Notch signaling pathway_Homo sapiens_hsa043300.32393139
119Arginine and proline metabolism_Homo sapiens_hsa003300.31450331
120cAMP signaling pathway_Homo sapiens_hsa040240.30851513
121Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.30003180
122Fatty acid degradation_Homo sapiens_hsa000710.29819508
123Glutathione metabolism_Homo sapiens_hsa004800.28911818
124Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.27676269
125Central carbon metabolism in cancer_Homo sapiens_hsa052300.27606902
126Fructose and mannose metabolism_Homo sapiens_hsa000510.26040847
127Sphingolipid metabolism_Homo sapiens_hsa006000.24506326
128Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.24440639
129Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.23754339
130Tight junction_Homo sapiens_hsa045300.22609770
131Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.21503646
132Melanogenesis_Homo sapiens_hsa049160.20602241
133Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.20227302
134Glucagon signaling pathway_Homo sapiens_hsa049220.20020708
135Axon guidance_Homo sapiens_hsa043600.19390786
136Steroid biosynthesis_Homo sapiens_hsa001000.18906936
137Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.17122974
138Mineral absorption_Homo sapiens_hsa049780.17024716
139Peroxisome_Homo sapiens_hsa041460.16887766
140Ras signaling pathway_Homo sapiens_hsa040140.16881943
141Ovarian steroidogenesis_Homo sapiens_hsa049130.16512479

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »