Rank | Gene Set | Z-score |
---|---|---|
1 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.54877098 |
2 | DNA replication initiation (GO:0006270) | 4.42796465 |
3 | DNA strand elongation (GO:0022616) | 4.35401798 |
4 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.22920523 |
5 | DNA unwinding involved in DNA replication (GO:0006268) | 4.22536321 |
6 | mitotic chromosome condensation (GO:0007076) | 4.21499183 |
7 | maturation of SSU-rRNA (GO:0030490) | 4.20219888 |
8 | DNA replication checkpoint (GO:0000076) | 4.15074958 |
9 | formation of translation preinitiation complex (GO:0001731) | 4.12522736 |
10 | mitotic metaphase plate congression (GO:0007080) | 4.09516258 |
11 | Golgi transport vesicle coating (GO:0048200) | 4.05771958 |
12 | COPI coating of Golgi vesicle (GO:0048205) | 4.05771958 |
13 | nucleobase biosynthetic process (GO:0046112) | 4.01688683 |
14 | purine nucleobase biosynthetic process (GO:0009113) | 3.85347980 |
15 | telomere maintenance via recombination (GO:0000722) | 3.81459691 |
16 | ribosomal small subunit assembly (GO:0000028) | 3.81131665 |
17 | ribosomal small subunit biogenesis (GO:0042274) | 3.76301414 |
18 | ribosome assembly (GO:0042255) | 3.70891143 |
19 | protein localization to kinetochore (GO:0034501) | 3.70361409 |
20 | mitotic recombination (GO:0006312) | 3.62576483 |
21 | mitotic nuclear envelope disassembly (GO:0007077) | 3.62445006 |
22 | ribosomal large subunit biogenesis (GO:0042273) | 3.60241613 |
23 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.58394027 |
24 | metaphase plate congression (GO:0051310) | 3.58185715 |
25 | CENP-A containing nucleosome assembly (GO:0034080) | 3.56700875 |
26 | viral transcription (GO:0019083) | 3.56700496 |
27 | ribosome biogenesis (GO:0042254) | 3.55921486 |
28 | telomere maintenance via telomere lengthening (GO:0010833) | 3.53866647 |
29 | translational termination (GO:0006415) | 3.53013193 |
30 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.52674051 |
31 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.52227917 |
32 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.52227917 |
33 | chromatin remodeling at centromere (GO:0031055) | 3.48977607 |
34 | kinetochore organization (GO:0051383) | 3.46210255 |
35 | nuclear pore organization (GO:0006999) | 3.44705025 |
36 | IMP biosynthetic process (GO:0006188) | 3.39431371 |
37 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.37697830 |
38 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.35566836 |
39 | rRNA processing (GO:0006364) | 3.34308067 |
40 | pore complex assembly (GO:0046931) | 3.34127339 |
41 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.31787185 |
42 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.31787185 |
43 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.31586302 |
44 | DNA replication-independent nucleosome organization (GO:0034724) | 3.31586302 |
45 | DNA topological change (GO:0006265) | 3.31050809 |
46 | membrane disassembly (GO:0030397) | 3.30820583 |
47 | nuclear envelope disassembly (GO:0051081) | 3.30820583 |
48 | translational initiation (GO:0006413) | 3.30356398 |
49 | regulation of translational fidelity (GO:0006450) | 3.29301421 |
50 | regulation of spindle organization (GO:0090224) | 3.27641419 |
51 | DNA deamination (GO:0045006) | 3.27432006 |
52 | spliceosomal snRNP assembly (GO:0000387) | 3.25586761 |
53 | kinetochore assembly (GO:0051382) | 3.24742219 |
54 | rRNA metabolic process (GO:0016072) | 3.24624839 |
55 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.23874087 |
56 | nuclear pore complex assembly (GO:0051292) | 3.23846687 |
57 | establishment of chromosome localization (GO:0051303) | 3.23778289 |
58 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 3.23762757 |
59 | proline biosynthetic process (GO:0006561) | 3.20778178 |
60 | protein localization to chromosome, centromeric region (GO:0071459) | 3.20605756 |
61 | translational elongation (GO:0006414) | 3.15311698 |
62 | establishment of integrated proviral latency (GO:0075713) | 3.12461251 |
63 | transcription-coupled nucleotide-excision repair (GO:0006283) | 3.12407055 |
64 | rRNA modification (GO:0000154) | 3.11817916 |
65 | mitotic sister chromatid segregation (GO:0000070) | 3.11463519 |
66 | positive regulation of chromosome segregation (GO:0051984) | 3.06584274 |
67 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.04715890 |
68 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.04134253 |
69 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.04072707 |
70 | proteasome assembly (GO:0043248) | 3.03689787 |
71 | histone exchange (GO:0043486) | 3.03391991 |
72 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 2.99614829 |
73 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.99318299 |
74 | sister chromatid segregation (GO:0000819) | 2.98321185 |
75 | termination of RNA polymerase I transcription (GO:0006363) | 2.98296389 |
76 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.97563604 |
77 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.97350267 |
78 | regulation of helicase activity (GO:0051095) | 2.97229018 |
79 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.94759707 |
80 | mismatch repair (GO:0006298) | 2.94433937 |
81 | cotranslational protein targeting to membrane (GO:0006613) | 2.94294041 |
82 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.92470442 |
83 | protein targeting to ER (GO:0045047) | 2.91210744 |
84 | negative regulation of chromosome segregation (GO:0051985) | 2.90395279 |
85 | spindle checkpoint (GO:0031577) | 2.89954155 |
86 | spliceosomal complex assembly (GO:0000245) | 2.89846292 |
87 | regulation of histone H3-K27 methylation (GO:0061085) | 2.89284849 |
88 | termination of RNA polymerase III transcription (GO:0006386) | 2.89101712 |
89 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.89101712 |
90 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.88211074 |
91 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 2.87515724 |
92 | negative regulation of sister chromatid segregation (GO:0033046) | 2.87515724 |
93 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 2.87515724 |
94 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 2.87515724 |
95 | DNA duplex unwinding (GO:0032508) | 2.87222745 |
96 | viral mRNA export from host cell nucleus (GO:0046784) | 2.86754877 |
97 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 2.86350829 |
98 | positive regulation of gamma-delta T cell activation (GO:0046645) | 2.86078936 |
99 | folic acid-containing compound biosynthetic process (GO:0009396) | 2.86025904 |
100 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 2.86023682 |
101 | regulation of chromosome segregation (GO:0051983) | 2.85983379 |
102 | DNA geometric change (GO:0032392) | 2.85655355 |
103 | IMP metabolic process (GO:0046040) | 2.85614553 |
104 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 2.85064295 |
105 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 2.84920345 |
106 | G1/S transition of mitotic cell cycle (GO:0000082) | 2.84625562 |
107 | cell cycle G1/S phase transition (GO:0044843) | 2.84625562 |
108 | cellular protein complex disassembly (GO:0043624) | 2.82534449 |
109 | telomere organization (GO:0032200) | 2.82443918 |
110 | mitotic spindle checkpoint (GO:0071174) | 2.82221234 |
111 | spindle assembly checkpoint (GO:0071173) | 2.82195234 |
112 | mitotic spindle assembly checkpoint (GO:0007094) | 2.81898573 |
113 | RNA splicing, via transesterification reactions (GO:0000375) | 2.80734881 |
114 | telomere maintenance (GO:0000723) | 2.80562854 |
115 | regulation of mitotic spindle organization (GO:0060236) | 2.78735973 |
116 | pseudouridine synthesis (GO:0001522) | 2.78518120 |
117 | chromosome condensation (GO:0030261) | 2.76739043 |
118 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.75053323 |
119 | negative regulation of mRNA processing (GO:0050686) | 2.71911241 |
120 | pentose-phosphate shunt (GO:0006098) | 2.70443510 |
121 | mRNA stabilization (GO:0048255) | 2.68662325 |
122 | RNA stabilization (GO:0043489) | 2.68662325 |
123 | negative regulation of RNA splicing (GO:0033119) | 2.68066230 |
124 | heterochromatin organization (GO:0070828) | 2.66883602 |
125 | regulation of RNA export from nucleus (GO:0046831) | 2.63853440 |
126 | thymic T cell selection (GO:0045061) | 2.63313411 |
127 | activation of Rac GTPase activity (GO:0032863) | 2.61841865 |
128 | negative regulation of mRNA metabolic process (GO:1903312) | 2.57342734 |
129 | DNA conformation change (GO:0071103) | 2.56587249 |
130 | viral life cycle (GO:0019058) | 2.55759652 |
131 | protein maturation by protein folding (GO:0022417) | 2.51074588 |
132 | positive thymic T cell selection (GO:0045059) | 2.50338018 |
133 | regulation of translational termination (GO:0006449) | 2.48780781 |
134 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 2.46961462 |
135 | pinocytosis (GO:0006907) | 2.46725860 |
136 | nucleobase-containing small molecule interconversion (GO:0015949) | 2.44957358 |
137 | negative thymic T cell selection (GO:0045060) | 2.42035267 |
138 | trophectodermal cell differentiation (GO:0001829) | 2.41333540 |
139 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 2.40970496 |
140 | dosage compensation (GO:0007549) | 2.40073997 |
141 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 2.37708097 |
142 | protein export from nucleus (GO:0006611) | 2.36238061 |
143 | NIK/NF-kappaB signaling (GO:0038061) | 2.35180459 |
144 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 2.34931252 |
145 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 2.34283706 |
146 | peptidyl-arginine omega-N-methylation (GO:0035247) | 2.34282096 |
147 | protein complex disassembly (GO:0043241) | 2.33615008 |
148 | regulation of nucleobase-containing compound transport (GO:0032239) | 2.33283698 |
149 | nuclear envelope organization (GO:0006998) | 2.32211192 |
150 | NADPH regeneration (GO:0006740) | 2.32073619 |
151 | DNA packaging (GO:0006323) | 2.31677885 |
152 | V(D)J recombination (GO:0033151) | 2.30527990 |
153 | B cell receptor signaling pathway (GO:0050853) | 2.30216759 |
154 | embryonic process involved in female pregnancy (GO:0060136) | 2.29741982 |
155 | negative T cell selection (GO:0043383) | 2.28958938 |
156 | cellular response to interleukin-4 (GO:0071353) | 2.27552602 |
157 | cellular hyperosmotic response (GO:0071474) | 2.26930010 |
158 | protein localization to endoplasmic reticulum (GO:0070972) | 2.26507195 |
159 | protein-DNA complex disassembly (GO:0032986) | 2.21663608 |
160 | nucleosome disassembly (GO:0006337) | 2.21663608 |
161 | establishment of viral latency (GO:0019043) | 2.20949594 |
162 | regulation of superoxide anion generation (GO:0032928) | 2.19732811 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 8.81433450 |
2 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.17492346 |
3 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.82279319 |
4 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.64229708 |
5 | * EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.27193925 |
6 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.19562459 |
7 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.11695812 |
8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.10119234 |
9 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 3.09502832 |
10 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.84961867 |
11 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.79823171 |
12 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.78699005 |
13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.78059002 |
14 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.76478865 |
15 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.52971544 |
16 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.41574036 |
17 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.34832467 |
18 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.30430537 |
19 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.29618171 |
20 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.28301976 |
21 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.26988770 |
22 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.24816611 |
23 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.21405104 |
24 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.21330047 |
25 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.14146766 |
26 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 2.09544131 |
27 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.06080337 |
28 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.01453198 |
29 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.98982656 |
30 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.96545952 |
31 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.95164300 |
32 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.94837623 |
33 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.94321942 |
34 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.82788896 |
35 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.82593499 |
36 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.80713340 |
37 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.80127714 |
38 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.79789448 |
39 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.78330252 |
40 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.78001242 |
41 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.76562379 |
42 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.74515807 |
43 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.70433589 |
44 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.69972902 |
45 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.68589219 |
46 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.63457280 |
47 | * ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.61883820 |
48 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.59366097 |
49 | MAF_26560356_Chip-Seq_TH1_Human | 1.58924456 |
50 | * EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.58611583 |
51 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.57770300 |
52 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.54923424 |
53 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.53012633 |
54 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.51948519 |
55 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.47620439 |
56 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.47340384 |
57 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.43522426 |
58 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.43483331 |
59 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.43266754 |
60 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.43101378 |
61 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.42183700 |
62 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.41575917 |
63 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.41035163 |
64 | * UTX_26944678_Chip-Seq_JUKART_Human | 1.39461687 |
65 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.39249407 |
66 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.38662290 |
67 | MYC_22102868_ChIP-Seq_BL_Human | 1.35721356 |
68 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.35492580 |
69 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.35492580 |
70 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.35492580 |
71 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.35070590 |
72 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.34422745 |
73 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 1.34192445 |
74 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.33314350 |
75 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.31571567 |
76 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.30144145 |
77 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.29693054 |
78 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.28817209 |
79 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.28365113 |
80 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.27663022 |
81 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.27574226 |
82 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.24747225 |
83 | * MAF_26560356_Chip-Seq_TH2_Human | 1.24138527 |
84 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.23604907 |
85 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.23488268 |
86 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.23093914 |
87 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.22528521 |
88 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.22382660 |
89 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.21884207 |
90 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.21619017 |
91 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.21063630 |
92 | * MYB_26560356_Chip-Seq_TH1_Human | 1.18577656 |
93 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.18289773 |
94 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.17172737 |
95 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.16062204 |
96 | * HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.15188868 |
97 | MYB_26560356_Chip-Seq_TH2_Human | 1.14257291 |
98 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.14168564 |
99 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.13865268 |
100 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.13387219 |
101 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.12959858 |
102 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.12566009 |
103 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.12137610 |
104 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.12108244 |
105 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.11278557 |
106 | * KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.10866892 |
107 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.09611115 |
108 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.08185637 |
109 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.08093228 |
110 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.07785000 |
111 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.04457227 |
112 | * E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.03923720 |
113 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.03681211 |
114 | * CHD1_26751641_Chip-Seq_LNCaP_Human | 1.03583869 |
115 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.02681850 |
116 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.02099403 |
117 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.01594997 |
118 | * KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.01322484 |
119 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.01193675 |
120 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.00917789 |
121 | ATF3_27146783_Chip-Seq_COLON_Human | 1.00820855 |
122 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.00363066 |
123 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.99911177 |
124 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.99878036 |
125 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 0.96171986 |
126 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 0.95362507 |
127 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.93715935 |
128 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.92857982 |
129 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.92743643 |
130 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.91185258 |
131 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.90113396 |
132 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.89567999 |
133 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.87618089 |
134 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.86281523 |
135 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.86253689 |
136 | VDR_21846776_ChIP-Seq_THP-1_Human | 0.85045186 |
137 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.84191220 |
138 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.82908889 |
139 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.82281309 |
140 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.81506685 |
141 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.80632437 |
142 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 0.77997494 |
143 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.76279509 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 4.78950176 |
2 | MP0010094_abnormal_chromosome_stability | 4.50744389 |
3 | MP0008057_abnormal_DNA_replication | 4.42549214 |
4 | MP0003111_abnormal_nucleus_morphology | 4.17923602 |
5 | MP0004957_abnormal_blastocyst_morpholog | 3.98156987 |
6 | * MP0003077_abnormal_cell_cycle | 3.66737073 |
7 | MP0008058_abnormal_DNA_repair | 3.46429235 |
8 | MP0008007_abnormal_cellular_replicative | 2.73520885 |
9 | MP0010234_abnormal_vibrissa_follicle | 2.67503118 |
10 | MP0008932_abnormal_embryonic_tissue | 2.58591733 |
11 | MP0002877_abnormal_melanocyte_morpholog | 2.50325278 |
12 | MP0002396_abnormal_hematopoietic_system | 2.30851352 |
13 | MP0005451_abnormal_body_composition | 2.29868622 |
14 | MP0003705_abnormal_hypodermis_morpholog | 2.20560371 |
15 | MP0008877_abnormal_DNA_methylation | 2.13001753 |
16 | * MP0001730_embryonic_growth_arrest | 2.03303184 |
17 | * MP0000350_abnormal_cell_proliferation | 2.03287752 |
18 | MP0003123_paternal_imprinting | 2.02963785 |
19 | MP0003786_premature_aging | 1.99311187 |
20 | MP0002166_altered_tumor_susceptibility | 1.83130140 |
21 | MP0003436_decreased_susceptibility_to | 1.82638539 |
22 | MP0002009_preneoplasia | 1.74480485 |
23 | MP0004185_abnormal_adipocyte_glucose | 1.71790327 |
24 | MP0010352_gastrointestinal_tract_polyps | 1.70105270 |
25 | MP0004264_abnormal_extraembryonic_tissu | 1.68782095 |
26 | MP0003941_abnormal_skin_development | 1.59783823 |
27 | MP0003718_maternal_effect | 1.59074429 |
28 | MP0003763_abnormal_thymus_physiology | 1.57402929 |
29 | MP0000490_abnormal_crypts_of | 1.55738998 |
30 | MP0001873_stomach_inflammation | 1.54370834 |
31 | MP0009333_abnormal_splenocyte_physiolog | 1.54166655 |
32 | MP0008260_abnormal_autophagy | 1.53588433 |
33 | MP0006292_abnormal_olfactory_placode | 1.53283796 |
34 | MP0002796_impaired_skin_barrier | 1.51070653 |
35 | MP0001697_abnormal_embryo_size | 1.49284388 |
36 | MP0010307_abnormal_tumor_latency | 1.49039432 |
37 | * MP0001672_abnormal_embryogenesis/_devel | 1.48897426 |
38 | * MP0005380_embryogenesis_phenotype | 1.48897426 |
39 | MP0005058_abnormal_lysosome_morphology | 1.48276794 |
40 | MP0002006_tumorigenesis | 1.47594836 |
41 | MP0003566_abnormal_cell_adhesion | 1.47233273 |
42 | MP0003300_gastrointestinal_ulcer | 1.46786036 |
43 | MP0004947_skin_inflammation | 1.46387644 |
44 | MP0002085_abnormal_embryonic_tissue | 1.39983097 |
45 | MP0004808_abnormal_hematopoietic_stem | 1.37367568 |
46 | MP0003303_peritoneal_inflammation | 1.36361432 |
47 | * MP0002080_prenatal_lethality | 1.35420565 |
48 | MP0005000_abnormal_immune_tolerance | 1.34572170 |
49 | * MP0000313_abnormal_cell_death | 1.32572783 |
50 | MP0000703_abnormal_thymus_morphology | 1.32274770 |
51 | MP0010030_abnormal_orbit_morphology | 1.31223417 |
52 | MP0002019_abnormal_tumor_incidence | 1.30235382 |
53 | * MP0003984_embryonic_growth_retardation | 1.28477415 |
54 | MP0002084_abnormal_developmental_patter | 1.25193025 |
55 | MP0005464_abnormal_platelet_physiology | 1.24876612 |
56 | * MP0002088_abnormal_embryonic_growth/wei | 1.24621980 |
57 | MP0003315_abnormal_perineum_morphology | 1.23139319 |
58 | MP0002210_abnormal_sex_determination | 1.21851469 |
59 | MP0003453_abnormal_keratinocyte_physiol | 1.21195436 |
60 | * MP0002398_abnormal_bone_marrow | 1.20725846 |
61 | MP0005387_immune_system_phenotype | 1.19707271 |
62 | MP0001790_abnormal_immune_system | 1.19707271 |
63 | MP0003567_abnormal_fetal_cardiomyocyte | 1.19156023 |
64 | MP0005025_abnormal_response_to | 1.18770760 |
65 | MP0000678_abnormal_parathyroid_gland | 1.18273627 |
66 | MP0004197_abnormal_fetal_growth/weight/ | 1.17179056 |
67 | MP0001293_anophthalmia | 1.17133015 |
68 | MP0002722_abnormal_immune_system | 1.17083224 |
69 | MP0003121_genomic_imprinting | 1.16367902 |
70 | MP0003191_abnormal_cellular_cholesterol | 1.15989227 |
71 | * MP0002086_abnormal_extraembryonic_tissu | 1.14655025 |
72 | MP0003866_abnormal_defecation | 1.13741470 |
73 | MP0001849_ear_inflammation | 1.10301837 |
74 | MP0000689_abnormal_spleen_morphology | 1.08606527 |
75 | MP0004133_heterotaxia | 1.07754229 |
76 | MP0001216_abnormal_epidermal_layer | 1.06324243 |
77 | MP0001145_abnormal_male_reproductive | 1.06224405 |
78 | MP0003136_yellow_coat_color | 1.05376556 |
79 | MP0001545_abnormal_hematopoietic_system | 1.05065280 |
80 | MP0005397_hematopoietic_system_phenotyp | 1.05065280 |
81 | MP0009278_abnormal_bone_marrow | 0.96672251 |
82 | MP0002419_abnormal_innate_immunity | 0.94971127 |
83 | MP0005671_abnormal_response_to | 0.94196718 |
84 | * MP0002429_abnormal_blood_cell | 0.94016546 |
85 | MP0001800_abnormal_humoral_immune | 0.93063639 |
86 | MP0004233_abnormal_muscle_weight | 0.92280294 |
87 | MP0001929_abnormal_gametogenesis | 0.90097851 |
88 | * MP0000716_abnormal_immune_system | 0.89544149 |
89 | MP0002938_white_spotting | 0.88727947 |
90 | MP0000858_altered_metastatic_potential | 0.87303277 |
91 | MP0000653_abnormal_sex_gland | 0.86400263 |
92 | MP0009785_altered_susceptibility_to | 0.84843840 |
93 | MP0004858_abnormal_nervous_system | 0.84645646 |
94 | MP0005666_abnormal_adipose_tissue | 0.84592756 |
95 | MP0002160_abnormal_reproductive_system | 0.83373833 |
96 | MP0001845_abnormal_inflammatory_respons | 0.83336568 |
97 | MP0003937_abnormal_limbs/digits/tail_de | 0.83147618 |
98 | MP0002148_abnormal_hypersensitivity_rea | 0.82648734 |
99 | MP0000537_abnormal_urethra_morphology | 0.82509572 |
100 | MP0001881_abnormal_mammary_gland | 0.82422619 |
101 | MP0009931_abnormal_skin_appearance | 0.82321030 |
102 | MP0002111_abnormal_tail_morphology | 0.80305818 |
103 | MP0005075_abnormal_melanosome_morpholog | 0.79946578 |
104 | MP0000685_abnormal_immune_system | 0.79387241 |
105 | MP0000465_gastrointestinal_hemorrhage | 0.79076955 |
106 | MP0001286_abnormal_eye_development | 0.78795016 |
107 | MP0005076_abnormal_cell_differentiation | 0.78731317 |
108 | MP0003890_abnormal_embryonic-extraembry | 0.78539180 |
109 | MP0002132_abnormal_respiratory_system | 0.78448299 |
110 | * MP0002420_abnormal_adaptive_immunity | 0.78422602 |
111 | MP0003806_abnormal_nucleotide_metabolis | 0.78172868 |
112 | MP0001835_abnormal_antigen_presentation | 0.78136861 |
113 | MP0004782_abnormal_surfactant_physiolog | 0.76776185 |
114 | * MP0001819_abnormal_immune_cell | 0.76765189 |
115 | MP0001727_abnormal_embryo_implantation | 0.76757630 |
116 | MP0003091_abnormal_cell_migration | 0.75980159 |
117 | * MP0002452_abnormal_antigen_presenting | 0.75657754 |
118 | MP0005023_abnormal_wound_healing | 0.75092945 |
119 | MP0002060_abnormal_skin_morphology | 0.74546621 |
120 | MP0002405_respiratory_system_inflammati | 0.74449625 |
121 | MP0009672_abnormal_birth_weight | 0.72804308 |
122 | MP0003119_abnormal_digestive_system | 0.72733000 |
123 | MP0002723_abnormal_immune_serum | 0.71332652 |
124 | MP0005389_reproductive_system_phenotype | 0.69681966 |
125 | MP0005384_cellular_phenotype | 0.69469169 |
126 | MP0005621_abnormal_cell_physiology | 0.68421265 |
127 | MP0001119_abnormal_female_reproductive | 0.67569389 |
128 | MP0003938_abnormal_ear_development | 0.66804659 |
129 | MP0002653_abnormal_ependyma_morphology | 0.66299703 |
130 | MP0003448_altered_tumor_morphology | 0.65755492 |
131 | MP0009379_abnormal_foot_pigmentation | 0.64587111 |
132 | MP0006054_spinal_hemorrhage | 0.63759015 |
133 | MP0002092_abnormal_eye_morphology | 0.63599348 |
134 | MP0000428_abnormal_craniofacial_morphol | 0.63457575 |
135 | MP0000049_abnormal_middle_ear | 0.62360211 |
136 | MP0002095_abnormal_skin_pigmentation | 0.62145455 |
137 | MP0000477_abnormal_intestine_morphology | 0.61332840 |
138 | MP0005501_abnormal_skin_physiology | 0.60520645 |
139 | MP0004381_abnormal_hair_follicle | 0.59612926 |
140 | MP0001853_heart_inflammation | 0.59106546 |
141 | MP0009053_abnormal_anal_canal | 0.58546889 |
142 | MP0010155_abnormal_intestine_physiology | 0.58387251 |
143 | MP0000358_abnormal_cell_content/ | 0.58220903 |
144 | MP0002277_abnormal_respiratory_mucosa | 0.57806427 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Birth length less than 3rd percentile (HP:0003561) | 4.70416877 |
2 | Breast hypoplasia (HP:0003187) | 4.11719603 |
3 | Reticulocytopenia (HP:0001896) | 4.05269572 |
4 | Chromsome breakage (HP:0040012) | 3.71971209 |
5 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.62727302 |
6 | Carpal bone hypoplasia (HP:0001498) | 3.23741757 |
7 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.18927760 |
8 | Patellar aplasia (HP:0006443) | 3.17236618 |
9 | Meckel diverticulum (HP:0002245) | 3.04183239 |
10 | Cerebral hypomyelination (HP:0006808) | 3.03932563 |
11 | Absent radius (HP:0003974) | 2.99285895 |
12 | Abnormal number of erythroid precursors (HP:0012131) | 2.98688702 |
13 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.97361552 |
14 | Abnormality of the preputium (HP:0100587) | 2.97148423 |
15 | Selective tooth agenesis (HP:0001592) | 2.94936550 |
16 | Rough bone trabeculation (HP:0100670) | 2.93985011 |
17 | Abnormality of the ileum (HP:0001549) | 2.92663518 |
18 | Recurrent viral infections (HP:0004429) | 2.92407560 |
19 | Abnormality of chromosome stability (HP:0003220) | 2.87755753 |
20 | Absent forearm bone (HP:0003953) | 2.83862348 |
21 | Aplasia involving forearm bones (HP:0009822) | 2.83862348 |
22 | Degeneration of anterior horn cells (HP:0002398) | 2.77768900 |
23 | Abnormality of the anterior horn cell (HP:0006802) | 2.77768900 |
24 | Medulloblastoma (HP:0002885) | 2.75876977 |
25 | Eczematoid dermatitis (HP:0000976) | 2.75796713 |
26 | Oral leukoplakia (HP:0002745) | 2.75751609 |
27 | Colon cancer (HP:0003003) | 2.75155300 |
28 | Colitis (HP:0002583) | 2.69505594 |
29 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.69422206 |
30 | Cellulitis (HP:0100658) | 2.69420590 |
31 | Ependymoma (HP:0002888) | 2.66231644 |
32 | Duplicated collecting system (HP:0000081) | 2.66177633 |
33 | Absent thumb (HP:0009777) | 2.60270193 |
34 | Agnosia (HP:0010524) | 2.59553359 |
35 | Agammaglobulinemia (HP:0004432) | 2.59053825 |
36 | Impulsivity (HP:0100710) | 2.55545788 |
37 | Seborrheic dermatitis (HP:0001051) | 2.54359808 |
38 | Aplastic anemia (HP:0001915) | 2.53465864 |
39 | Macrocytic anemia (HP:0001972) | 2.52041933 |
40 | Supernumerary spleens (HP:0009799) | 2.47980285 |
41 | Hyperacusis (HP:0010780) | 2.47550141 |
42 | Ectopic kidney (HP:0000086) | 2.45611971 |
43 | Ankyloglossia (HP:0010296) | 2.44810647 |
44 | Gastrointestinal stroma tumor (HP:0100723) | 2.43175858 |
45 | Duodenal stenosis (HP:0100867) | 2.42547978 |
46 | Small intestinal stenosis (HP:0012848) | 2.42547978 |
47 | Bone marrow hypocellularity (HP:0005528) | 2.42244617 |
48 | Progressive muscle weakness (HP:0003323) | 2.41965198 |
49 | Hypertensive crisis (HP:0100735) | 2.41694527 |
50 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.41013423 |
51 | Myelodysplasia (HP:0002863) | 2.39451833 |
52 | Abnormality of the renal collecting system (HP:0004742) | 2.37916517 |
53 | Pallor (HP:0000980) | 2.36233044 |
54 | Gastrointestinal inflammation (HP:0004386) | 2.35756823 |
55 | Abnormal number of incisors (HP:0011064) | 2.35536826 |
56 | Premature graying of hair (HP:0002216) | 2.34807011 |
57 | Abnormality of oral frenula (HP:0000190) | 2.34667185 |
58 | Flat acetabular roof (HP:0003180) | 2.29752783 |
59 | Abnormality of the labia minora (HP:0012880) | 2.28830592 |
60 | Neoplasm of the pancreas (HP:0002894) | 2.28198504 |
61 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.23998566 |
62 | Triphalangeal thumb (HP:0001199) | 2.23269355 |
63 | Abnormal trabecular bone morphology (HP:0100671) | 2.22424593 |
64 | Horseshoe kidney (HP:0000085) | 2.21968329 |
65 | Microvesicular hepatic steatosis (HP:0001414) | 2.21367722 |
66 | Abnormal lung lobation (HP:0002101) | 2.21200703 |
67 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.19979786 |
68 | Abnormal gallbladder physiology (HP:0012438) | 2.19523935 |
69 | Cholecystitis (HP:0001082) | 2.19523935 |
70 | Lymphoma (HP:0002665) | 2.19450365 |
71 | Increased IgE level (HP:0003212) | 2.17299663 |
72 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 2.17266127 |
73 | Asplenia (HP:0001746) | 2.17017356 |
74 | Tracheoesophageal fistula (HP:0002575) | 2.14521400 |
75 | Trismus (HP:0000211) | 2.14310612 |
76 | Viral hepatitis (HP:0006562) | 2.12772762 |
77 | Cleft eyelid (HP:0000625) | 2.12095297 |
78 | Abnormality of the fingertips (HP:0001211) | 2.11842470 |
79 | IgM deficiency (HP:0002850) | 2.10827914 |
80 | Sloping forehead (HP:0000340) | 2.10330016 |
81 | Autoimmune hemolytic anemia (HP:0001890) | 2.08775763 |
82 | Basal cell carcinoma (HP:0002671) | 2.08404639 |
83 | Ragged-red muscle fibers (HP:0003200) | 2.07795363 |
84 | Amaurosis fugax (HP:0100576) | 2.07213710 |
85 | Short thumb (HP:0009778) | 2.06887711 |
86 | Obstructive lung disease (HP:0006536) | 2.06338512 |
87 | Chronic obstructive pulmonary disease (HP:0006510) | 2.06338512 |
88 | Broad face (HP:0000283) | 2.06038497 |
89 | Abnormality of the duodenum (HP:0002246) | 2.05794684 |
90 | Atresia of the external auditory canal (HP:0000413) | 2.05652751 |
91 | Inflammation of the large intestine (HP:0002037) | 2.05356885 |
92 | Cellular immunodeficiency (HP:0005374) | 2.03909304 |
93 | 11 pairs of ribs (HP:0000878) | 2.02926027 |
94 | Progressive external ophthalmoplegia (HP:0000590) | 2.02796015 |
95 | Vertebral compression fractures (HP:0002953) | 2.02502630 |
96 | Squamous cell carcinoma (HP:0002860) | 2.02395898 |
97 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.01092864 |
98 | Panhypogammaglobulinemia (HP:0003139) | 2.00522690 |
99 | Abnormality of DNA repair (HP:0003254) | 2.00070143 |
100 | Abnormality of small intestinal villus morphology (HP:0011472) | 1.99916272 |
101 | Villous atrophy (HP:0011473) | 1.99916272 |
102 | Hypoplasia of the radius (HP:0002984) | 1.98905523 |
103 | Ureteral duplication (HP:0000073) | 1.98618295 |
104 | Meningitis (HP:0001287) | 1.95564175 |
105 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.95294949 |
106 | Proximal placement of thumb (HP:0009623) | 1.95215000 |
107 | Fatigue (HP:0012378) | 1.93262976 |
108 | Orthostatic hypotension (HP:0001278) | 1.93062963 |
109 | Abnormality of T cell physiology (HP:0011840) | 1.91951492 |
110 | IgG deficiency (HP:0004315) | 1.91180532 |
111 | Papilloma (HP:0012740) | 1.90957852 |
112 | Verrucae (HP:0200043) | 1.90957852 |
113 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.90533297 |
114 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 1.90096407 |
115 | Severe combined immunodeficiency (HP:0004430) | 1.89856145 |
116 | Irregular epiphyses (HP:0010582) | 1.88764765 |
117 | Combined immunodeficiency (HP:0005387) | 1.88529193 |
118 | Rhabdomyosarcoma (HP:0002859) | 1.87542592 |
119 | Recurrent abscess formation (HP:0002722) | 1.87295426 |
120 | Abnormality of the umbilical cord (HP:0010881) | 1.84095315 |
121 | Abnormality of reticulocytes (HP:0004312) | 1.83324972 |
122 | Deviation of the thumb (HP:0009603) | 1.83110415 |
123 | Lymphopenia (HP:0001888) | 1.82534125 |
124 | Microretrognathia (HP:0000308) | 1.81729470 |
125 | Absent epiphyses (HP:0010577) | 1.81579110 |
126 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 1.81579110 |
127 | IgA deficiency (HP:0002720) | 1.81517403 |
128 | Abnormality of the fetal cardiovascular system (HP:0010948) | 1.80673025 |
129 | Abnormal umbilical cord blood vessels (HP:0011403) | 1.80673025 |
130 | Single umbilical artery (HP:0001195) | 1.80673025 |
131 | Septate vagina (HP:0001153) | 1.80483255 |
132 | Hemorrhage of the eye (HP:0011885) | 1.79625854 |
133 | Premature ovarian failure (HP:0008209) | 1.79616452 |
134 | Stenosis of the external auditory canal (HP:0000402) | 1.79494520 |
135 | Granulocytopenia (HP:0001913) | 1.79029703 |
136 | Thrombocytosis (HP:0001894) | 1.77158463 |
137 | Poikiloderma (HP:0001029) | 1.76690934 |
138 | Micronodular cirrhosis (HP:0001413) | 1.76178739 |
139 | Disproportionate tall stature (HP:0001519) | 1.75014822 |
140 | Recurrent bacterial skin infections (HP:0005406) | 1.74777746 |
141 | Osteomyelitis (HP:0002754) | 1.74400906 |
142 | Sparse lateral eyebrow (HP:0005338) | 1.73355399 |
143 | Abnormality of T cells (HP:0002843) | 1.73013079 |
144 | Entropion (HP:0000621) | 1.72949397 |
145 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.72931903 |
146 | Clubbing of toes (HP:0100760) | 1.72843193 |
147 | Pancytopenia (HP:0001876) | 1.72171544 |
148 | Recurrent fungal infections (HP:0002841) | 1.72067178 |
149 | Aplasia/Hypoplasia of the earlobes (HP:0009906) | 1.71747447 |
150 | Osteolytic defects of the hand bones (HP:0009699) | 1.71352288 |
151 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.71352288 |
152 | Secondary amenorrhea (HP:0000869) | 1.70564660 |
153 | Abnormal foot bone ossification (HP:0010675) | 1.70243077 |
154 | Glossoptosis (HP:0000162) | 1.69411278 |
155 | Breast aplasia (HP:0100783) | 1.69106559 |
156 | Neoplasm of the oral cavity (HP:0100649) | 1.68990921 |
157 | Abnormality of the carotid arteries (HP:0005344) | 1.68557821 |
158 | Abnormality of abdominal situs (HP:0011620) | 1.68481194 |
159 | Abdominal situs inversus (HP:0003363) | 1.68481194 |
160 | Mediastinal lymphadenopathy (HP:0100721) | 1.67187411 |
161 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.65852068 |
162 | Reticulocytosis (HP:0001923) | 1.65680904 |
163 | Long palpebral fissure (HP:0000637) | 1.65491617 |
164 | Insomnia (HP:0100785) | 1.64873761 |
165 | Abnormality of macrophages (HP:0004311) | 1.64679450 |
166 | Increased nuchal translucency (HP:0010880) | 1.64413632 |
167 | Asymmetry of the thorax (HP:0001555) | 1.64301865 |
168 | Abnormality of the thoracic spine (HP:0100711) | 1.64280341 |
169 | B lymphocytopenia (HP:0010976) | 1.63090974 |
170 | Progressive hearing impairment (HP:0001730) | 1.63077455 |
171 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.63008318 |
172 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.60698108 |
173 | Abnormality of the thymus (HP:0000777) | 1.59958104 |
174 | Metaphyseal cupping (HP:0003021) | 1.59567120 |
175 | Distal lower limb amyotrophy (HP:0008944) | 1.57774256 |
176 | Hepatitis (HP:0012115) | 1.57680939 |
177 | Patellar dislocation (HP:0002999) | 1.57297061 |
178 | Deep palmar crease (HP:0006191) | 1.54544702 |
179 | Skin ulcer (HP:0200042) | 1.53860030 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BUB1 | 4.87155857 |
2 | WEE1 | 4.22129939 |
3 | SMG1 | 3.58958208 |
4 | CDC7 | 3.51211580 |
5 | TRIB3 | 3.40517417 |
6 | EIF2AK1 | 2.99759285 |
7 | TSSK6 | 2.94515006 |
8 | ERN1 | 2.75241519 |
9 | PRPF4B | 2.69644130 |
10 | STK16 | 2.55025862 |
11 | SRPK1 | 2.45341890 |
12 | NEK2 | 2.36862021 |
13 | PLK4 | 2.36658395 |
14 | MKNK1 | 2.11472212 |
15 | TTK | 2.10674127 |
16 | SCYL2 | 2.02053685 |
17 | ICK | 1.93337104 |
18 | NME2 | 1.92930866 |
19 | TESK2 | 1.92601054 |
20 | PLK1 | 1.91221325 |
21 | BRSK2 | 1.91036302 |
22 | EIF2AK3 | 1.88221052 |
23 | RIPK4 | 1.85826378 |
24 | MKNK2 | 1.81608899 |
25 | PASK | 1.80228829 |
26 | VRK1 | 1.78853909 |
27 | CDK7 | 1.78787568 |
28 | MST1R | 1.69555075 |
29 | SIK1 | 1.64655916 |
30 | FGFR4 | 1.64421926 |
31 | PLK3 | 1.63173127 |
32 | ACVR1B | 1.62956961 |
33 | ATR | 1.56842477 |
34 | TLK1 | 1.56673905 |
35 | RPS6KB2 | 1.55952809 |
36 | AURKB | 1.53507350 |
37 | STK10 | 1.50150636 |
38 | MAP3K14 | 1.45135531 |
39 | VRK2 | 1.40794055 |
40 | MST4 | 1.39014689 |
41 | CDK12 | 1.38214677 |
42 | DYRK3 | 1.37690988 |
43 | EPHA2 | 1.36538511 |
44 | PNCK | 1.35303604 |
45 | TGFBR1 | 1.30576047 |
46 | NEK1 | 1.29904969 |
47 | MAP4K1 | 1.29572199 |
48 | MAP3K13 | 1.24876605 |
49 | CHEK2 | 1.23081685 |
50 | CHEK1 | 1.16640648 |
51 | STK4 | 1.15900458 |
52 | PBK | 1.13951715 |
53 | MAP3K8 | 1.12401404 |
54 | AURKA | 1.10313853 |
55 | RPS6KA4 | 1.07490605 |
56 | PKN2 | 1.06610138 |
57 | PAK4 | 1.05948659 |
58 | CDK4 | 1.03503754 |
59 | PIM2 | 1.01339430 |
60 | BRD4 | 1.01307966 |
61 | ZAK | 1.00985202 |
62 | PTK6 | 1.00656451 |
63 | KDR | 0.99628983 |
64 | KSR2 | 0.98614390 |
65 | BRSK1 | 0.97006898 |
66 | CLK1 | 0.95028240 |
67 | TXK | 0.94304521 |
68 | IRAK4 | 0.89326570 |
69 | MAPK11 | 0.87785915 |
70 | EIF2AK2 | 0.87241582 |
71 | RIPK1 | 0.83303624 |
72 | ATM | 0.83293437 |
73 | SIK3 | 0.83067091 |
74 | BLK | 0.82753499 |
75 | PIM1 | 0.81968047 |
76 | TESK1 | 0.80388535 |
77 | CDK2 | 0.76445787 |
78 | PRKCI | 0.74263405 |
79 | CCNB1 | 0.73991940 |
80 | TBK1 | 0.73788695 |
81 | GRK6 | 0.71534368 |
82 | IRAK3 | 0.71042124 |
83 | ALK | 0.70437356 |
84 | ARAF | 0.69770030 |
85 | * CSNK2A2 | 0.68393509 |
86 | EEF2K | 0.67677502 |
87 | CDK8 | 0.67205712 |
88 | * CSNK2A1 | 0.66556112 |
89 | PAK1 | 0.65749791 |
90 | ZAP70 | 0.65746368 |
91 | BTK | 0.61813277 |
92 | MELK | 0.61723105 |
93 | FLT3 | 0.61427987 |
94 | BMX | 0.60961288 |
95 | MAP2K2 | 0.60500505 |
96 | MTOR | 0.59528572 |
97 | CDK1 | 0.59345339 |
98 | MAP3K1 | 0.58202922 |
99 | STK3 | 0.58164234 |
100 | PDGFRA | 0.57876490 |
101 | RPS6KA5 | 0.57776232 |
102 | AKT3 | 0.56770489 |
103 | CSF1R | 0.56764051 |
104 | MAP3K3 | 0.55489003 |
105 | CDK9 | 0.54528368 |
106 | MAP3K10 | 0.50770373 |
107 | CSK | 0.50388259 |
108 | TAF1 | 0.47390541 |
109 | CDK6 | 0.46925940 |
110 | JAK3 | 0.44998657 |
111 | MET | 0.44686992 |
112 | LMTK2 | 0.43906710 |
113 | TEC | 0.43617168 |
114 | YES1 | 0.43296018 |
115 | LRRK2 | 0.43028545 |
116 | BMPR2 | 0.42817712 |
117 | RAF1 | 0.42571267 |
118 | FGFR3 | 0.42189115 |
119 | NLK | 0.41673277 |
120 | MAPKAPK2 | 0.40282584 |
121 | EPHB1 | 0.37904688 |
122 | NEK9 | 0.36810221 |
123 | LIMK1 | 0.36737954 |
124 | LYN | 0.36675429 |
125 | MAP2K3 | 0.35980083 |
126 | TYK2 | 0.35189820 |
127 | KIT | 0.35166722 |
128 | LCK | 0.35105885 |
129 | IKBKB | 0.34962755 |
130 | RET | 0.34852558 |
131 | NEK6 | 0.34685718 |
132 | JAK1 | 0.34618906 |
133 | HIPK2 | 0.34431328 |
134 | DYRK2 | 0.34124861 |
135 | CDC42BPA | 0.33033173 |
136 | PDPK1 | 0.32445946 |
137 | MAP3K2 | 0.32203840 |
138 | CSNK1G3 | 0.29990348 |
139 | BRAF | 0.28851387 |
140 | STK38L | 0.27168823 |
141 | BCR | 0.26546178 |
142 | * CSNK1E | 0.25867091 |
143 | PRKDC | 0.25555418 |
144 | STK24 | 0.24550644 |
145 | TAOK2 | 0.24129964 |
146 | PAK2 | 0.22929210 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 4.59860129 |
2 | Mismatch repair_Homo sapiens_hsa03430 | 4.15359710 |
3 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.54009762 |
4 | Ribosome_Homo sapiens_hsa03010 | 3.42340306 |
5 | RNA polymerase_Homo sapiens_hsa03020 | 3.41210401 |
6 | Proteasome_Homo sapiens_hsa03050 | 3.34286936 |
7 | Spliceosome_Homo sapiens_hsa03040 | 3.25477450 |
8 | Homologous recombination_Homo sapiens_hsa03440 | 3.11869888 |
9 | RNA transport_Homo sapiens_hsa03013 | 2.95452303 |
10 | Base excision repair_Homo sapiens_hsa03410 | 2.89661921 |
11 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.85530711 |
12 | * Cell cycle_Homo sapiens_hsa04110 | 2.57045083 |
13 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.43104471 |
14 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.39200480 |
15 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.37106366 |
16 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.20545754 |
17 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.14293308 |
18 | Basal transcription factors_Homo sapiens_hsa03022 | 2.12031270 |
19 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.93302175 |
20 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.85264833 |
21 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.83787734 |
22 | RNA degradation_Homo sapiens_hsa03018 | 1.81625862 |
23 | * Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.68366227 |
24 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.65675191 |
25 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.61730237 |
26 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.60438143 |
27 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.57982397 |
28 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.48049890 |
29 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.40364545 |
30 | Bladder cancer_Homo sapiens_hsa05219 | 1.36727952 |
31 | Purine metabolism_Homo sapiens_hsa00230 | 1.32735318 |
32 | * Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.27501076 |
33 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.23379936 |
34 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.22895919 |
35 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.11643082 |
36 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.07942556 |
37 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.03512163 |
38 | Carbon metabolism_Homo sapiens_hsa01200 | 1.03349221 |
39 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.00711300 |
40 | Protein export_Homo sapiens_hsa03060 | 0.96963822 |
41 | Galactose metabolism_Homo sapiens_hsa00052 | 0.95945048 |
42 | Hepatitis C_Homo sapiens_hsa05160 | 0.93039601 |
43 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.91632685 |
44 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.87495442 |
45 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.86940504 |
46 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.86546564 |
47 | Endometrial cancer_Homo sapiens_hsa05213 | 0.85284992 |
48 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.83909985 |
49 | * Viral carcinogenesis_Homo sapiens_hsa05203 | 0.83465464 |
50 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.83411163 |
51 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.78679230 |
52 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.75995413 |
53 | HTLV-I infection_Homo sapiens_hsa05166 | 0.75616245 |
54 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.74486471 |
55 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.73908021 |
56 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.72381181 |
57 | Measles_Homo sapiens_hsa05162 | 0.71782138 |
58 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.70298320 |
59 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.67399656 |
60 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.66213810 |
61 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.63869694 |
62 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.63010474 |
63 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.61813145 |
64 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.61087985 |
65 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.60995771 |
66 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.59298578 |
67 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.58304444 |
68 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.57556054 |
69 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.56684400 |
70 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.56109648 |
71 | Legionellosis_Homo sapiens_hsa05134 | 0.56094318 |
72 | * MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.54113791 |
73 | Allograft rejection_Homo sapiens_hsa05330 | 0.51811064 |
74 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.51306878 |
75 | Glioma_Homo sapiens_hsa05214 | 0.50785115 |
76 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.50303689 |
77 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.50121137 |
78 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.49888434 |
79 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.48817518 |
80 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.47663812 |
81 | Tuberculosis_Homo sapiens_hsa05152 | 0.47529238 |
82 | Prion diseases_Homo sapiens_hsa05020 | 0.47383732 |
83 | * Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.45883333 |
84 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.45419617 |
85 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.45302517 |
86 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.45293702 |
87 | Salmonella infection_Homo sapiens_hsa05132 | 0.45243531 |
88 | Thyroid cancer_Homo sapiens_hsa05216 | 0.45078254 |
89 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.45062473 |
90 | Apoptosis_Homo sapiens_hsa04210 | 0.44756046 |
91 | Asthma_Homo sapiens_hsa05310 | 0.44722702 |
92 | Shigellosis_Homo sapiens_hsa05131 | 0.43673811 |
93 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.43006606 |
94 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.42853185 |
95 | Lysine degradation_Homo sapiens_hsa00310 | 0.42801083 |
96 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.42364800 |
97 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.41919257 |
98 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.41237213 |
99 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.41037111 |
100 | * Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.40315371 |
101 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.39151413 |
102 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.37709810 |
103 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.37261247 |
104 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.36151110 |
105 | Huntingtons disease_Homo sapiens_hsa05016 | 0.34385285 |
106 | Hepatitis B_Homo sapiens_hsa05161 | 0.34160794 |
107 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.34150275 |
108 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.33617875 |
109 | Viral myocarditis_Homo sapiens_hsa05416 | 0.31740556 |
110 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.31087572 |
111 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.30717582 |
112 | Influenza A_Homo sapiens_hsa05164 | 0.29111745 |
113 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.27657491 |
114 | * Pathways in cancer_Homo sapiens_hsa05200 | 0.27454700 |
115 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.27373334 |
116 | Sulfur relay system_Homo sapiens_hsa04122 | 0.27262897 |
117 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.26829313 |
118 | Colorectal cancer_Homo sapiens_hsa05210 | 0.26148920 |
119 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.25504635 |
120 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.25365002 |
121 | * Notch signaling pathway_Homo sapiens_hsa04330 | 0.25006747 |
122 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.24032957 |
123 | Leishmaniasis_Homo sapiens_hsa05140 | 0.23881107 |
124 | Other glycan degradation_Homo sapiens_hsa00511 | 0.22051360 |
125 | Prostate cancer_Homo sapiens_hsa05215 | 0.19589873 |
126 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.19315712 |
127 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.17995640 |
128 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.16618443 |
129 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.16030601 |
130 | Metabolic pathways_Homo sapiens_hsa01100 | 0.15940945 |
131 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.15902243 |
132 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.15433260 |
133 | Adherens junction_Homo sapiens_hsa04520 | 0.15259586 |
134 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.14405130 |
135 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.13934927 |
136 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.13712786 |