HDDC2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)6.28506212
2chaperone-mediated protein transport (GO:0072321)5.56933446
3viral transcription (GO:0019083)5.56791895
4translational termination (GO:0006415)5.38855808
5ribosomal small subunit biogenesis (GO:0042274)5.36789766
6maturation of SSU-rRNA (GO:0030490)5.17280700
7respiratory electron transport chain (GO:0022904)4.87414160
8SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.84531361
9translational elongation (GO:0006414)4.80246164
10cotranslational protein targeting to membrane (GO:0006613)4.77016307
11electron transport chain (GO:0022900)4.74251276
12ribosomal large subunit biogenesis (GO:0042273)4.73148783
13DNA deamination (GO:0045006)4.73082488
14protein targeting to ER (GO:0045047)4.72026692
15mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.64718234
16protein localization to endoplasmic reticulum (GO:0070972)4.47714433
17establishment of protein localization to endoplasmic reticulum (GO:0072599)4.46313373
18energy coupled proton transport, down electrochemical gradient (GO:0015985)4.42016603
19ATP synthesis coupled proton transport (GO:0015986)4.42016603
20translational initiation (GO:0006413)4.36869108
21telomere maintenance via semi-conservative replication (GO:0032201)4.34839964
22cellular protein complex disassembly (GO:0043624)4.33359409
23establishment of integrated proviral latency (GO:0075713)4.32219630
24viral life cycle (GO:0019058)4.28317215
25DNA strand elongation involved in DNA replication (GO:0006271)4.24013598
26nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.20073645
27mitochondrial respiratory chain complex assembly (GO:0033108)4.14827749
28formation of translation preinitiation complex (GO:0001731)4.13610653
29regulation of mitochondrial translation (GO:0070129)4.13574935
30deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.12240006
31protein neddylation (GO:0045116)4.11407880
32proteasome assembly (GO:0043248)4.03696225
33DNA strand elongation (GO:0022616)4.02976553
34translation (GO:0006412)3.98626099
35ribonucleoprotein complex biogenesis (GO:0022613)3.95159838
36negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.87257277
37cullin deneddylation (GO:0010388)3.85542902
38telomere maintenance via recombination (GO:0000722)3.83662436
39DNA replication initiation (GO:0006270)3.83424388
40protein targeting to mitochondrion (GO:0006626)3.79753901
41protein complex disassembly (GO:0043241)3.79131381
42oxidative phosphorylation (GO:0006119)3.76574541
43protein deneddylation (GO:0000338)3.73021818
44inner mitochondrial membrane organization (GO:0007007)3.64937447
45macromolecular complex disassembly (GO:0032984)3.63682508
46positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.61223918
47rRNA processing (GO:0006364)3.60307007
48regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.58809098
49DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.58356786
50establishment of protein localization to mitochondrial membrane (GO:0090151)3.54942268
51negative regulation of ligase activity (GO:0051352)3.54869864
52negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.54869864
53spliceosomal snRNP assembly (GO:0000387)3.54166289
54signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.53731177
55intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.53731177
56transcription-coupled nucleotide-excision repair (GO:0006283)3.53298020
57establishment of protein localization to mitochondrion (GO:0072655)3.52202603
58anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.52173284
59pseudouridine synthesis (GO:0001522)3.51946935
60mitotic recombination (GO:0006312)3.50620108
61signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.50547691
62signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.50547691
63signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.50547691
64regulation of cellular amino acid metabolic process (GO:0006521)3.47749839
65cellular component biogenesis (GO:0044085)3.47279918
66nucleotide-excision repair, DNA gap filling (GO:0006297)3.46879185
67protein localization to mitochondrion (GO:0070585)3.46589816
68telomere maintenance via telomere lengthening (GO:0010833)3.46273721
69nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.45772071
70establishment of viral latency (GO:0019043)3.45680381
71ATP biosynthetic process (GO:0006754)3.44200844
72rRNA metabolic process (GO:0016072)3.43856031
73CENP-A containing nucleosome assembly (GO:0034080)3.42385246
747-methylguanosine mRNA capping (GO:0006370)3.41791497
75signal transduction involved in DNA damage checkpoint (GO:0072422)3.40395282
76signal transduction involved in DNA integrity checkpoint (GO:0072401)3.40395282
77RNA capping (GO:0036260)3.39493668
787-methylguanosine RNA capping (GO:0009452)3.39493668
79mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.39355075
80mitochondrial respiratory chain complex I assembly (GO:0032981)3.39355075
81NADH dehydrogenase complex assembly (GO:0010257)3.39355075
82respiratory chain complex IV assembly (GO:0008535)3.38024298
83antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.37429476
84viral mRNA export from host cell nucleus (GO:0046784)3.35816854
85signal transduction involved in cell cycle checkpoint (GO:0072395)3.35775088
86nucleobase biosynthetic process (GO:0046112)3.35161304
87nuclear-transcribed mRNA catabolic process (GO:0000956)3.34535404
88GTP biosynthetic process (GO:0006183)3.32451756
89transcription elongation from RNA polymerase I promoter (GO:0006362)3.31237333
90rRNA methylation (GO:0031167)3.30909525
91deoxyribose phosphate biosynthetic process (GO:0046385)3.30086563
922-deoxyribonucleotide biosynthetic process (GO:0009265)3.30086563
93histone exchange (GO:0043486)3.28930846
94chromatin remodeling at centromere (GO:0031055)3.28929569
95tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.28042976
96RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.28042976
97deoxyribonucleotide biosynthetic process (GO:0009263)3.27450408
98positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.24446929
99DNA unwinding involved in DNA replication (GO:0006268)3.23775589
100termination of RNA polymerase I transcription (GO:0006363)3.23330480
101transcription elongation from RNA polymerase III promoter (GO:0006385)3.23127005
102termination of RNA polymerase III transcription (GO:0006386)3.23127005
103cytochrome complex assembly (GO:0017004)3.21927492
104purine nucleoside triphosphate biosynthetic process (GO:0009145)3.20286276
105purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.19412616
106nucleobase-containing small molecule interconversion (GO:0015949)3.18328289
107spliceosomal complex assembly (GO:0000245)3.18053020
108rRNA modification (GO:0000154)3.16978197
109mRNA catabolic process (GO:0006402)3.16742355
110purine nucleobase biosynthetic process (GO:0009113)3.15892735
111antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.14979692
112pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.13897728
113protein complex biogenesis (GO:0070271)3.13594249
114ribosome biogenesis (GO:0042254)3.12419101
115transcription from RNA polymerase I promoter (GO:0006360)3.12361331
116purine nucleoside monophosphate biosynthetic process (GO:0009127)3.12293323
117purine ribonucleoside monophosphate biosynthetic process (GO:0009168)3.12293323
118DNA replication checkpoint (GO:0000076)3.12140403
119mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.11702022
120UTP biosynthetic process (GO:0006228)3.10549071
121DNA replication-independent nucleosome organization (GO:0034724)3.09702540
122DNA replication-independent nucleosome assembly (GO:0006336)3.09702540
123guanosine-containing compound biosynthetic process (GO:1901070)3.09548248
124IMP biosynthetic process (GO:0006188)3.09287304
125protein targeting to membrane (GO:0006612)3.09212783
126positive regulation of ligase activity (GO:0051351)3.08517951
127kinetochore assembly (GO:0051382)3.08163023
128exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.08111197
129G1/S transition of mitotic cell cycle (GO:0000082)3.07067106
130ribonucleoside triphosphate biosynthetic process (GO:0009201)3.04033917
131mitochondrial transport (GO:0006839)3.00421864

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.85084281
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.85723177
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.38886813
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.05236095
5GABP_17652178_ChIP-ChIP_JURKAT_Human3.98837505
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.98226401
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.57887875
8HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.46971593
9ETS1_20019798_ChIP-Seq_JURKAT_Human3.43037835
10E2F4_17652178_ChIP-ChIP_JURKAT_Human3.29673791
11MYC_18358816_ChIP-ChIP_MESCs_Mouse3.22629647
12SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.19545019
13MYC_19079543_ChIP-ChIP_MESCs_Mouse3.15766259
14NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.12412969
15CREB1_15753290_ChIP-ChIP_HEK293T_Human3.09378036
16* MYC_19030024_ChIP-ChIP_MESCs_Mouse3.04642970
17CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.92999143
18ELF1_17652178_ChIP-ChIP_JURKAT_Human2.80331655
19HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.78623272
20XRN2_22483619_ChIP-Seq_HELA_Human2.63890120
21VDR_23849224_ChIP-Seq_CD4+_Human2.59693945
22FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.49645201
23* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.42458450
24DCP1A_22483619_ChIP-Seq_HELA_Human2.38075608
25* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.37016773
26TTF2_22483619_ChIP-Seq_HELA_Human2.33189266
27ELK1_19687146_ChIP-ChIP_HELA_Human2.29049508
28FOXP3_21729870_ChIP-Seq_TREG_Human2.27676690
29THAP11_20581084_ChIP-Seq_MESCs_Mouse2.26314266
30CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.22760096
31SRF_21415370_ChIP-Seq_HL-1_Mouse2.10104887
32YY1_21170310_ChIP-Seq_MESCs_Mouse2.04504836
33GABP_19822575_ChIP-Seq_HepG2_Human1.99680736
34* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.98994909
35* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.93110101
36ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.88867276
37MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.86624574
38E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.82975905
39TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.80465358
40HOXB4_20404135_ChIP-ChIP_EML_Mouse1.76772468
41FOXM1_23109430_ChIP-Seq_U2OS_Human1.76696654
42YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.75152662
43MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.69647641
44* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.68378614
45PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.62574710
46POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.61731599
47MYCN_18555785_ChIP-Seq_MESCs_Mouse1.61337130
48PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.58992677
49E2F1_21310950_ChIP-Seq_MCF-7_Human1.58724379
50NANOG_18555785_ChIP-Seq_MESCs_Mouse1.58145244
51* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.49396585
52MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.48862980
53* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.48608514
54ELK1_22589737_ChIP-Seq_MCF10A_Human1.44259191
55CIITA_25753668_ChIP-Seq_RAJI_Human1.43470796
56MYC_18940864_ChIP-ChIP_HL60_Human1.40000401
57POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.38877115
58NOTCH1_21737748_ChIP-Seq_TLL_Human1.38647002
59AR_21909140_ChIP-Seq_LNCAP_Human1.38144915
60CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.35686912
61RBPJ_22232070_ChIP-Seq_NCS_Mouse1.31714100
62* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.29944987
63BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.25380998
64ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.24092384
65HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.22979814
66CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.22497510
67PADI4_21655091_ChIP-ChIP_MCF-7_Human1.21242536
68* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.20229558
69KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.19500105
70TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.18811050
71CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.16615852
72EWS_26573619_Chip-Seq_HEK293_Human1.14104493
73KDM5A_27292631_Chip-Seq_BREAST_Human1.12397240
74SOX2_18555785_ChIP-Seq_MESCs_Mouse1.08883459
75HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.08508809
76CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.07557500
77* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.06800114
78* FUS_26573619_Chip-Seq_HEK293_Human1.05231403
79* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.03811789
80* KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.99662057
81SOX2_16153702_ChIP-ChIP_HESCs_Human0.98974784
82E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.97439416
83TP63_19390658_ChIP-ChIP_HaCaT_Human0.95862648
84STAT3_1855785_ChIP-Seq_MESCs_Mouse0.95030513
85ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.94981389
86HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.94796558
87POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.94503265
88CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.94483341
89TFEB_21752829_ChIP-Seq_HELA_Human0.93356034
90VDR_22108803_ChIP-Seq_LS180_Human0.92601697
91POU5F1_16153702_ChIP-ChIP_HESCs_Human0.90811377
92* SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.88494101
93EGR1_19374776_ChIP-ChIP_THP-1_Human0.87548225
94* SPI1_23547873_ChIP-Seq_NB4_Human0.87384236
95CTCF_18555785_ChIP-Seq_MESCs_Mouse0.83035139
96DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.82991305
97CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.81644259
98FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.80406449
99IRF1_19129219_ChIP-ChIP_H3396_Human0.79629817
100SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.77880895
101OCT4_18692474_ChIP-Seq_MEFs_Mouse0.77870411
102CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.75884474
103IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.75654713
104SOX17_20123909_ChIP-Seq_XEN_Mouse0.72691165
105KLF4_18555785_ChIP-Seq_MESCs_Mouse0.72457816
106CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.71507245
107DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.71192459
108TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.69366312
109NANOG_16153702_ChIP-ChIP_HESCs_Human0.68984435
110NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.68318942
111NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.67629208
112SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.67153064
113KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.67034225
114FOXP1_21924763_ChIP-Seq_HESCs_Human0.66950787
115* PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.66926759
116ZNF274_21170338_ChIP-Seq_K562_Hela0.66638092
117MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.65795227
118SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.64653891
119SALL1_21062744_ChIP-ChIP_HESCs_Human0.64565380
120FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.63860472
121SOX2_18692474_ChIP-Seq_MEFs_Mouse0.63799844
122ESR1_15608294_ChIP-ChIP_MCF-7_Human0.62986483
123TP53_22573176_ChIP-Seq_HFKS_Human0.62232125

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.16920593
2MP0009379_abnormal_foot_pigmentation3.88828785
3MP0004957_abnormal_blastocyst_morpholog3.87980113
4MP0010094_abnormal_chromosome_stability3.77399933
5MP0008058_abnormal_DNA_repair3.35852334
6MP0008057_abnormal_DNA_replication3.33586515
7MP0003077_abnormal_cell_cycle3.25115602
8MP0003111_abnormal_nucleus_morphology3.03218616
9MP0006292_abnormal_olfactory_placode2.87002615
10MP0008932_abnormal_embryonic_tissue2.66348996
11MP0008007_abnormal_cellular_replicative2.60031509
12MP0003123_paternal_imprinting2.47494486
13MP0002396_abnormal_hematopoietic_system2.44318054
14MP0002638_abnormal_pupillary_reflex2.32628321
15MP0002837_dystrophic_cardiac_calcinosis2.16272890
16MP0003806_abnormal_nucleotide_metabolis2.14504116
17MP0000372_irregular_coat_pigmentation2.02879261
18MP0003786_premature_aging1.96723314
19MP0008877_abnormal_DNA_methylation1.76366381
20MP0002132_abnormal_respiratory_system1.75011474
21MP0008995_early_reproductive_senescence1.73970503
22MP0003763_abnormal_thymus_physiology1.71297668
23MP0001529_abnormal_vocalization1.65941500
24MP0002102_abnormal_ear_morphology1.60257649
25MP0000490_abnormal_crypts_of1.52710400
26MP0002938_white_spotting1.51690067
27MP0003186_abnormal_redox_activity1.51177405
28MP0000350_abnormal_cell_proliferation1.48127856
29MP0003646_muscle_fatigue1.44856014
30MP0001853_heart_inflammation1.44428889
31MP0003880_abnormal_central_pattern1.41376287
32MP0003121_genomic_imprinting1.39612799
33MP0001905_abnormal_dopamine_level1.39450832
34MP0005075_abnormal_melanosome_morpholog1.38520946
35MP0002751_abnormal_autonomic_nervous1.38156610
36MP0004145_abnormal_muscle_electrophysio1.36854470
37MP0005174_abnormal_tail_pigmentation1.36400379
38MP0003718_maternal_effect1.33430874
39MP0004215_abnormal_myocardial_fiber1.33308289
40MP0003937_abnormal_limbs/digits/tail_de1.31338795
41MP0001730_embryonic_growth_arrest1.31326721
42MP0004808_abnormal_hematopoietic_stem1.31065910
43MP0000049_abnormal_middle_ear1.30383464
44MP0006036_abnormal_mitochondrial_physio1.30149069
45MP0003315_abnormal_perineum_morphology1.28194165
46MP0001188_hyperpigmentation1.27724135
47MP0002160_abnormal_reproductive_system1.26322634
48MP0003136_yellow_coat_color1.23703660
49MP0002095_abnormal_skin_pigmentation1.20861872
50MP0005171_absent_coat_pigmentation1.17377844
51MP0000015_abnormal_ear_pigmentation1.16408732
52MP0000313_abnormal_cell_death1.15779805
53MP0004133_heterotaxia1.14688502
54MP0006035_abnormal_mitochondrial_morpho1.14449835
55MP0006276_abnormal_autonomic_nervous1.13919414
56MP0000749_muscle_degeneration1.09719787
57MP0003122_maternal_imprinting1.09500018
58MP0009333_abnormal_splenocyte_physiolog1.09430741
59MP0001835_abnormal_antigen_presentation1.08958149
60MP0005408_hypopigmentation1.08460071
61MP0005646_abnormal_pituitary_gland1.06704473
62MP0001485_abnormal_pinna_reflex1.05195293
63MP0002398_abnormal_bone_marrow1.03436296
64MP0000703_abnormal_thymus_morphology1.02919867
65MP0001697_abnormal_embryo_size1.02359297
66MP0002210_abnormal_sex_determination1.01712598
67MP0003567_abnormal_fetal_cardiomyocyte1.00677685
68MP0002019_abnormal_tumor_incidence1.00450542
69MP0000358_abnormal_cell_content/0.97905376
70MP0002080_prenatal_lethality0.97780699
71MP0005389_reproductive_system_phenotype0.97402758
72MP0001984_abnormal_olfaction0.96870200
73MP0003941_abnormal_skin_development0.94793751
74MP0004084_abnormal_cardiac_muscle0.94600446
75MP0002722_abnormal_immune_system0.94555296
76MP0005379_endocrine/exocrine_gland_phen0.94225607
77MP0003137_abnormal_impulse_conducting0.92866492
78MP0000631_abnormal_neuroendocrine_gland0.92458796
79MP0000689_abnormal_spleen_morphology0.92435478
80MP0010030_abnormal_orbit_morphology0.92029840
81MP0003011_delayed_dark_adaptation0.91406816
82MP0001968_abnormal_touch/_nociception0.90538600
83MP0009785_altered_susceptibility_to0.87037329
84MP0002234_abnormal_pharynx_morphology0.86839990
85MP0000858_altered_metastatic_potential0.85409645
86MP0001145_abnormal_male_reproductive0.84114609
87MP0002163_abnormal_gland_morphology0.84047232
88MP0001346_abnormal_lacrimal_gland0.83941992
89MP0006054_spinal_hemorrhage0.83694785
90MP0004142_abnormal_muscle_tone0.83230854
91MP0001764_abnormal_homeostasis0.83170702
92MP0008789_abnormal_olfactory_epithelium0.80603866
93MP0005253_abnormal_eye_physiology0.80163627
94MP0005409_darkened_coat_color0.78316317
95MP0009046_muscle_twitch0.78147684
96MP0005394_taste/olfaction_phenotype0.77650983
97MP0005499_abnormal_olfactory_system0.77650983
98MP0002233_abnormal_nose_morphology0.76848519
99MP0002429_abnormal_blood_cell0.76587890
100MP0002085_abnormal_embryonic_tissue0.75979956
101MP0005671_abnormal_response_to0.75413133
102MP0001293_anophthalmia0.75287203
103MP0005645_abnormal_hypothalamus_physiol0.75255586
104MP0005380_embryogenesis_phenotype0.74517179
105MP0001672_abnormal_embryogenesis/_devel0.74517179
106MP0005187_abnormal_penis_morphology0.74428809
107MP0009250_abnormal_appendicular_skeleto0.71718695
108MP0003942_abnormal_urinary_system0.70822427
109MP0003119_abnormal_digestive_system0.70773592
110MP0003698_abnormal_male_reproductive0.69330634
111MP0008872_abnormal_physiological_respon0.69090569
112MP0005670_abnormal_white_adipose0.69063642
113MP0004147_increased_porphyrin_level0.68040531
114MP0003938_abnormal_ear_development0.66921110
115MP0009697_abnormal_copulation0.66748056
116MP0000716_abnormal_immune_system0.66648456
117MP0002420_abnormal_adaptive_immunity0.66560926
118MP0006072_abnormal_retinal_apoptosis0.66516586
119MP0000653_abnormal_sex_gland0.65952154
120MP0001919_abnormal_reproductive_system0.65500087
121MP0002090_abnormal_vision0.65260878
122MP0010352_gastrointestinal_tract_polyps0.65196888
123MP0002736_abnormal_nociception_after0.64080647
124MP0001819_abnormal_immune_cell0.63682393
125MP0001119_abnormal_female_reproductive0.63272097
126MP0002277_abnormal_respiratory_mucosa0.63177963
127MP0002084_abnormal_developmental_patter0.62810667
128MP0005397_hematopoietic_system_phenotyp0.62026457
129MP0001545_abnormal_hematopoietic_system0.62026457
130MP0000750_abnormal_muscle_regeneration0.61800434
131MP0010386_abnormal_urinary_bladder0.59882831
132MP0001186_pigmentation_phenotype0.59797779
133MP0003890_abnormal_embryonic-extraembry0.59767889
134MP0000681_abnormal_thyroid_gland0.59106309
135MP0001929_abnormal_gametogenesis0.58532056
136MP0001286_abnormal_eye_development0.58084724
137MP0001727_abnormal_embryo_implantation0.56913562

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)5.43680478
2Reticulocytopenia (HP:0001896)4.99963332
3Abnormal number of erythroid precursors (HP:0012131)4.97337807
4Acute necrotizing encephalopathy (HP:0006965)4.81801594
5Mitochondrial inheritance (HP:0001427)4.34208155
6Abnormal mitochondria in muscle tissue (HP:0008316)4.31038481
7Birth length less than 3rd percentile (HP:0003561)4.26086711
8Aplastic anemia (HP:0001915)4.11565258
9Hepatocellular necrosis (HP:0001404)4.00291614
10Increased CSF lactate (HP:0002490)3.89344153
11Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.86139417
12Decreased activity of mitochondrial respiratory chain (HP:0008972)3.86139417
13Progressive macrocephaly (HP:0004481)3.85087480
14Acute encephalopathy (HP:0006846)3.57083176
15Increased hepatocellular lipid droplets (HP:0006565)3.56136095
16Macrocytic anemia (HP:0001972)3.52972293
17Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.46116680
18Pallor (HP:0000980)3.41804711
19Hepatic necrosis (HP:0002605)3.33260639
20Oral leukoplakia (HP:0002745)3.25096475
21Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.17042144
22Increased serum lactate (HP:0002151)3.03660782
23Breast hypoplasia (HP:0003187)3.00047951
24Exercise intolerance (HP:0003546)2.95565525
25Lipid accumulation in hepatocytes (HP:0006561)2.95470260
2611 pairs of ribs (HP:0000878)2.91157446
27Selective tooth agenesis (HP:0001592)2.86471698
283-Methylglutaconic aciduria (HP:0003535)2.80050232
29Type I transferrin isoform profile (HP:0003642)2.74454062
30Renal Fanconi syndrome (HP:0001994)2.71621062
31Aplasia/Hypoplasia of the sacrum (HP:0008517)2.68687547
32Chromsome breakage (HP:0040012)2.68310699
33Colon cancer (HP:0003003)2.66981111
34Increased muscle lipid content (HP:0009058)2.66242184
35Exertional dyspnea (HP:0002875)2.55393538
36Abnormality of alanine metabolism (HP:0010916)2.49789915
37Hyperalaninemia (HP:0003348)2.49789915
38Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.49789915
39Supernumerary spleens (HP:0009799)2.46955856
40Premature graying of hair (HP:0002216)2.46689707
41Increased serum pyruvate (HP:0003542)2.43797432
42Abnormality of glycolysis (HP:0004366)2.43797432
43Abnormality of the labia minora (HP:0012880)2.41009170
44Absent thumb (HP:0009777)2.38689277
45Respiratory difficulties (HP:0002880)2.37471266
46Lactic acidosis (HP:0003128)2.37438252
47Respiratory failure (HP:0002878)2.33655396
48Rough bone trabeculation (HP:0100670)2.29215168
49Optic disc pallor (HP:0000543)2.26286439
50Lethargy (HP:0001254)2.26166371
51Microvesicular hepatic steatosis (HP:0001414)2.25497433
52Hyperglycinemia (HP:0002154)2.25103855
53Short middle phalanx of the 5th finger (HP:0004220)2.24117252
54Degeneration of anterior horn cells (HP:0002398)2.22868926
55Abnormality of the anterior horn cell (HP:0006802)2.22868926
56Increased intramyocellular lipid droplets (HP:0012240)2.22258197
57Aplasia/Hypoplasia of the uvula (HP:0010293)2.21155929
58Asplenia (HP:0001746)2.21035123
59Patellar aplasia (HP:0006443)2.19729653
60Methylmalonic acidemia (HP:0002912)2.14886882
61Chromosomal breakage induced by crosslinking agents (HP:0003221)2.14517328
62Abnormality of serum amino acid levels (HP:0003112)2.12109932
63Microretrognathia (HP:0000308)2.11299889
64Muscle fiber atrophy (HP:0100295)2.11105284
65Abnormal lung lobation (HP:0002101)2.09572730
66Abnormality of the preputium (HP:0100587)2.08857810
67Abnormality of renal resorption (HP:0011038)2.08786790
68Pancreatic fibrosis (HP:0100732)2.07235965
69Emotional lability (HP:0000712)2.05517842
70Cerebral edema (HP:0002181)2.04948936
71Cellular immunodeficiency (HP:0005374)2.04874411
72Amniotic constriction ring (HP:0009775)2.04784909
73Abnormality of placental membranes (HP:0011409)2.04784909
74Type 2 muscle fiber atrophy (HP:0003554)2.03448045
75True hermaphroditism (HP:0010459)2.02289029
76Carpal bone hypoplasia (HP:0001498)2.01805504
77Methylmalonic aciduria (HP:0012120)2.01528030
78Abnormality of chromosome stability (HP:0003220)2.01402062
79Dry hair (HP:0011359)2.00963792
80Abnormality of urine glucose concentration (HP:0011016)2.00785490
81Glycosuria (HP:0003076)2.00785490
82CNS demyelination (HP:0007305)2.00462736
83Aplasia/Hypoplasia of the spleen (HP:0010451)2.00128333
84Aplasia/Hypoplasia of the patella (HP:0006498)2.00091463
85Pancreatic cysts (HP:0001737)1.98833837
86Abnormality of the columella (HP:0009929)1.98791603
87Meckel diverticulum (HP:0002245)1.96873952
88Hypothermia (HP:0002045)1.96448961
89Abnormality of methionine metabolism (HP:0010901)1.96033017
90Triphalangeal thumb (HP:0001199)1.94693954
91Reduced antithrombin III activity (HP:0001976)1.93803315
92Cleft eyelid (HP:0000625)1.93702680
93IgM deficiency (HP:0002850)1.91465090
94Glossoptosis (HP:0000162)1.90243639
95Sparse eyelashes (HP:0000653)1.89485254
96Pancytopenia (HP:0001876)1.88938719
97Abnormality of the ileum (HP:0001549)1.88574853
98Horseshoe kidney (HP:0000085)1.88205431
99Cerebral hypomyelination (HP:0006808)1.87165809
100Nephroblastoma (Wilms tumor) (HP:0002667)1.86658946
101Generalized aminoaciduria (HP:0002909)1.83977614
102X-linked dominant inheritance (HP:0001423)1.83524097
103Poor head control (HP:0002421)1.83336732
104Leukodystrophy (HP:0002415)1.83075425
105Median cleft lip (HP:0000161)1.82379159
106Abnormal protein glycosylation (HP:0012346)1.82248039
107Abnormal glycosylation (HP:0012345)1.82248039
108Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.82248039
109Abnormal protein N-linked glycosylation (HP:0012347)1.82248039
110Myelodysplasia (HP:0002863)1.80913618
111Depressed nasal ridge (HP:0000457)1.80378519
112Sclerocornea (HP:0000647)1.76103342
113Facial cleft (HP:0002006)1.76071559
114Duodenal stenosis (HP:0100867)1.75442422
115Small intestinal stenosis (HP:0012848)1.75442422
116Congenital, generalized hypertrichosis (HP:0004540)1.75428978
117Embryonal renal neoplasm (HP:0011794)1.75352727
118Abnormal number of incisors (HP:0011064)1.74834051
119Hyperphosphaturia (HP:0003109)1.72139379
120Preaxial hand polydactyly (HP:0001177)1.72091507
121Unsteady gait (HP:0002317)1.71001380
122Megaloblastic anemia (HP:0001889)1.70880143
123Hypoglycemic coma (HP:0001325)1.69853062
124Trismus (HP:0000211)1.68354321
125CNS hypomyelination (HP:0003429)1.67898038
126Abnormality of DNA repair (HP:0003254)1.67895203
127Lymphoma (HP:0002665)1.65095243
128Progressive muscle weakness (HP:0003323)1.63805459
129Dicarboxylic aciduria (HP:0003215)1.61899121
130Abnormality of dicarboxylic acid metabolism (HP:0010995)1.61899121
131Abnormality of cochlea (HP:0000375)1.61727197
132Multiple enchondromatosis (HP:0005701)1.61272794
133Abnormality of the duodenum (HP:0002246)1.57889626
134Poor suck (HP:0002033)1.57629486
135Abnormality of aspartate family amino acid metabolism (HP:0010899)1.57556785
136Abnormality of midbrain morphology (HP:0002418)1.54792831
137Molar tooth sign on MRI (HP:0002419)1.54792831
138Aplasia/hypoplasia of the uterus (HP:0008684)1.53375946

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK164.02539338
2VRK23.86274899
3NME23.83736867
4BUB13.71974212
5WEE13.60384219
6CDC73.40833357
7EIF2AK13.17411997
8EIF2AK33.02581863
9VRK12.75691153
10SRPK12.58751571
11NME12.19040817
12ACVR1B2.16668603
13PDK22.03926557
14TSSK61.96511595
15LIMK11.66935153
16PIM21.65686000
17TESK21.63024969
18PLK41.59323407
19BCKDK1.57497015
20MKNK11.56382064
21NUAK11.55245615
22TGFBR11.52203005
23MAP3K121.50803377
24ZAK1.48129700
25RPS6KB21.47898575
26BRSK21.45526395
27TESK11.43991549
28TLK11.42244986
29TRIM281.38224352
30CDK81.37103888
31PLK31.34190707
32PLK11.31905961
33AURKB1.29318922
34TNIK1.27360238
35DYRK31.21577748
36MAP4K21.21223893
37WNK31.21120166
38PASK1.21092207
39ATR1.18198278
40KDR1.17858265
41CDK71.17821185
42CCNB11.13162509
43CDK191.10461430
44AURKA1.09089790
45TTK1.08534972
46MYLK1.07202907
47BMPR1B1.06612479
48EIF2AK21.06536542
49FLT31.05023521
50ARAF1.03353536
51TAF11.02963511
52MST41.01772941
53MKNK20.97441815
54NEK10.96297188
55CAMKK20.93367235
56BRSK10.88167357
57BRAF0.87694859
58TEC0.83741813
59CSNK2A10.83168695
60ADRBK20.82910305
61PHKG20.81445081
62PHKG10.81445081
63PBK0.80892305
64RPS6KA40.80741223
65CSNK2A20.79079503
66PLK20.78974244
67STK40.77438016
68TXK0.76607637
69ALK0.73108017
70DYRK20.72418137
71IRAK30.72250764
72STK240.70267481
73GRK10.69347570
74DAPK30.68799396
75CHEK20.67594759
76SIK30.66430610
77MAPK130.66336307
78NEK20.65688090
79ILK0.64179817
80LRRK20.64143883
81KIT0.62770458
82CSNK1G10.61188599
83YES10.59550596
84WNK40.59245431
85CSNK1G30.59182871
86OBSCN0.58373581
87BTK0.57669608
88PAK40.56249873
89PRKCI0.56010345
90PRKCG0.55715519
91CSNK1E0.55383837
92ADRBK10.53465992
93CSNK1G20.53317105
94MAP4K10.53088563
95RPS6KA50.52869323
96PIK3CG0.52603773
97CHEK10.52164355
98EPHA20.51533091
99IRAK40.50883660
100PAK10.50717845
101ERBB30.50554551
102PNCK0.49040295
103MINK10.48334560
104MAP3K40.46626173
105BMPR20.45933950
106ATM0.45422226
107STK30.42771598
108MAP3K80.42194533
109MAP2K60.41426508
110CDK10.41353019
111GRK50.41066050
112SCYL20.41045514
113ABL20.40988069
114EPHA40.40880160
115SYK0.40240094
116LYN0.40141843
117GRK60.39928638
118CDK40.39176297
119DAPK10.39023023
120MATK0.39002058
121MAPKAPK50.38372660
122PIM10.37615571
123CDK20.37370202
124NEK60.36579605
125PRKDC0.36380348
126PINK10.36276018
127CDK30.36208819
128FGFR10.34817676
129MAP2K70.33862615
130GRK70.33551720
131ZAP700.33320796
132CAMK2G0.33251300
133STK390.32301954
134MAP3K110.32202112
135NLK0.31993128
136DMPK0.31927843
137MUSK0.31840287
138AKT20.31006346

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.16808480
2Proteasome_Homo sapiens_hsa030504.40566180
3DNA replication_Homo sapiens_hsa030304.32179032
4Mismatch repair_Homo sapiens_hsa034303.81995364
5RNA polymerase_Homo sapiens_hsa030203.36202621
6Oxidative phosphorylation_Homo sapiens_hsa001903.02507483
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.97728105
8Nucleotide excision repair_Homo sapiens_hsa034202.89623153
9Spliceosome_Homo sapiens_hsa030402.87064669
10Parkinsons disease_Homo sapiens_hsa050122.86176204
11Homologous recombination_Homo sapiens_hsa034402.72997612
12Pyrimidine metabolism_Homo sapiens_hsa002402.64734170
13Base excision repair_Homo sapiens_hsa034102.47500713
14Huntingtons disease_Homo sapiens_hsa050162.29821464
15RNA transport_Homo sapiens_hsa030132.29033878
16Non-homologous end-joining_Homo sapiens_hsa034502.08558822
17Protein export_Homo sapiens_hsa030601.93401537
18Alzheimers disease_Homo sapiens_hsa050101.89591173
19Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.81795016
20Basal transcription factors_Homo sapiens_hsa030221.78562529
21Cell cycle_Homo sapiens_hsa041101.78538197
22Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.75220740
23RNA degradation_Homo sapiens_hsa030181.75163452
24One carbon pool by folate_Homo sapiens_hsa006701.72679217
25Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.56388423
26Fanconi anemia pathway_Homo sapiens_hsa034601.54428060
27Purine metabolism_Homo sapiens_hsa002301.46085107
28Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.36828641
29Propanoate metabolism_Homo sapiens_hsa006401.32641207
30Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.22705816
312-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.18843714
32Fatty acid elongation_Homo sapiens_hsa000621.06927869
33Cardiac muscle contraction_Homo sapiens_hsa042601.04610898
34p53 signaling pathway_Homo sapiens_hsa041151.00832139
35mRNA surveillance pathway_Homo sapiens_hsa030150.99389389
36Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.99089193
37Epstein-Barr virus infection_Homo sapiens_hsa051690.97418306
38Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.96604090
39Vitamin B6 metabolism_Homo sapiens_hsa007500.93154390
40Selenocompound metabolism_Homo sapiens_hsa004500.83195302
41Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.81834058
42Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.77900852
43Sulfur relay system_Homo sapiens_hsa041220.70626620
44Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.69492788
45Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.68789383
46Primary immunodeficiency_Homo sapiens_hsa053400.68666644
47Steroid biosynthesis_Homo sapiens_hsa001000.67346006
48Arginine and proline metabolism_Homo sapiens_hsa003300.66384833
49Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.63913869
50Systemic lupus erythematosus_Homo sapiens_hsa053220.63513759
51Herpes simplex infection_Homo sapiens_hsa051680.62908919
52Sulfur metabolism_Homo sapiens_hsa009200.57498932
53Glutathione metabolism_Homo sapiens_hsa004800.57217178
54Thyroid cancer_Homo sapiens_hsa052160.56604200
55Butanoate metabolism_Homo sapiens_hsa006500.54952669
56N-Glycan biosynthesis_Homo sapiens_hsa005100.54022508
57Folate biosynthesis_Homo sapiens_hsa007900.53865811
58Oocyte meiosis_Homo sapiens_hsa041140.53318125
59Peroxisome_Homo sapiens_hsa041460.53185548
60Pentose phosphate pathway_Homo sapiens_hsa000300.52880630
61Antigen processing and presentation_Homo sapiens_hsa046120.52279656
62Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.49944605
63Metabolic pathways_Homo sapiens_hsa011000.47172815
64SNARE interactions in vesicular transport_Homo sapiens_hsa041300.46262042
65Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.45738432
66Legionellosis_Homo sapiens_hsa051340.43852874
67Viral carcinogenesis_Homo sapiens_hsa052030.41436163
68Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.41077932
69Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.40942246
70Arachidonic acid metabolism_Homo sapiens_hsa005900.40653588
71Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.40079776
72Phototransduction_Homo sapiens_hsa047440.38754324
73beta-Alanine metabolism_Homo sapiens_hsa004100.38521564
74HTLV-I infection_Homo sapiens_hsa051660.38295353
75Nitrogen metabolism_Homo sapiens_hsa009100.37368167
76Fatty acid metabolism_Homo sapiens_hsa012120.37354949
77Alcoholism_Homo sapiens_hsa050340.37020107
78Hematopoietic cell lineage_Homo sapiens_hsa046400.36791358
79Pentose and glucuronate interconversions_Homo sapiens_hsa000400.34521997
80Fatty acid degradation_Homo sapiens_hsa000710.34412005
81Nicotine addiction_Homo sapiens_hsa050330.34206692
82Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.33754473
83Galactose metabolism_Homo sapiens_hsa000520.33662174
84Drug metabolism - other enzymes_Homo sapiens_hsa009830.31928970
85Measles_Homo sapiens_hsa051620.30328094
86Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.30280122
87Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.29382498
88Shigellosis_Homo sapiens_hsa051310.28415714
89Cyanoamino acid metabolism_Homo sapiens_hsa004600.27011021
90Biosynthesis of amino acids_Homo sapiens_hsa012300.26456240
91Intestinal immune network for IgA production_Homo sapiens_hsa046720.26429839
92Cysteine and methionine metabolism_Homo sapiens_hsa002700.25080961
93Olfactory transduction_Homo sapiens_hsa047400.23791570
94Graft-versus-host disease_Homo sapiens_hsa053320.23785545
95Allograft rejection_Homo sapiens_hsa053300.23604595
96Tryptophan metabolism_Homo sapiens_hsa003800.23403835
97Arginine biosynthesis_Homo sapiens_hsa002200.22052192
98Carbon metabolism_Homo sapiens_hsa012000.21562057
99Tyrosine metabolism_Homo sapiens_hsa003500.21180430
100Maturity onset diabetes of the young_Homo sapiens_hsa049500.21005712
101Apoptosis_Homo sapiens_hsa042100.20922457
102Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.20885972
103Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.20611489
104Regulation of autophagy_Homo sapiens_hsa041400.19740938
105Vitamin digestion and absorption_Homo sapiens_hsa049770.19530762
106Autoimmune thyroid disease_Homo sapiens_hsa053200.18965299
107Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.18485689
108RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.17867888
109Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.17777455
110Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.17586474
111Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.17374440
112Vibrio cholerae infection_Homo sapiens_hsa051100.16251063
113Fructose and mannose metabolism_Homo sapiens_hsa000510.16034164
114Other glycan degradation_Homo sapiens_hsa005110.15977375
115Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.15607840
116Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.15359762
117Hepatitis B_Homo sapiens_hsa051610.15247220
118Asthma_Homo sapiens_hsa053100.13901103
119TGF-beta signaling pathway_Homo sapiens_hsa043500.13238493
120HIF-1 signaling pathway_Homo sapiens_hsa040660.12519004
121Synaptic vesicle cycle_Homo sapiens_hsa047210.12344428
122Phenylalanine metabolism_Homo sapiens_hsa003600.12236378
123Collecting duct acid secretion_Homo sapiens_hsa049660.11586491
124Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.11066139
125Retinol metabolism_Homo sapiens_hsa008300.10898836
126Transcriptional misregulation in cancer_Homo sapiens_hsa052020.10750441
127Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.10094802
128NOD-like receptor signaling pathway_Homo sapiens_hsa046210.09559811
129Chemical carcinogenesis_Homo sapiens_hsa052040.08951961
130Wnt signaling pathway_Homo sapiens_hsa043100.08710243
131Colorectal cancer_Homo sapiens_hsa052100.08273451
132Phagosome_Homo sapiens_hsa041450.08007776
133NF-kappa B signaling pathway_Homo sapiens_hsa040640.07737386
134Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.06319529
135Pyruvate metabolism_Homo sapiens_hsa006200.05971169
136Small cell lung cancer_Homo sapiens_hsa052220.05656317
137Influenza A_Homo sapiens_hsa051640.05067754
138Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.04609539
139Basal cell carcinoma_Homo sapiens_hsa052170.03436776

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