HERPUD2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.21553725
2positive regulation of gamma-delta T cell activation (GO:0046645)4.92921838
3negative T cell selection (GO:0043383)4.87404599
4negative regulation of cell killing (GO:0031342)4.65762659
5negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.65762659
6negative thymic T cell selection (GO:0045060)4.50055124
7activated T cell proliferation (GO:0050798)4.43986552
8positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.40774289
9axon ensheathment in central nervous system (GO:0032291)4.24337295
10central nervous system myelination (GO:0022010)4.24337295
11negative regulation of neurotransmitter secretion (GO:0046929)4.19157999
12regulation of B cell receptor signaling pathway (GO:0050855)4.06210772
13positive T cell selection (GO:0043368)4.00625321
14cellular response to interleukin-15 (GO:0071350)3.98779452
15tolerance induction (GO:0002507)3.97526744
16response to interleukin-15 (GO:0070672)3.87663965
17negative regulation of T cell mediated immunity (GO:0002710)3.75893651
18regulation of regulatory T cell differentiation (GO:0045589)3.72621910
19fatty acid elongation (GO:0030497)3.70327954
20regulation of gamma-delta T cell activation (GO:0046643)3.70209366
21cellular extravasation (GO:0045123)3.70106215
22RNA destabilization (GO:0050779)3.53481972
23cytidine metabolic process (GO:0046087)3.51181351
24cytidine catabolic process (GO:0006216)3.51181351
25cytidine deamination (GO:0009972)3.51181351
26positive thymic T cell selection (GO:0045059)3.49944008
27regulation of T cell tolerance induction (GO:0002664)3.47296896
28interferon-gamma production (GO:0032609)3.45914590
29regulation of gamma-delta T cell differentiation (GO:0045586)3.43646212
30antigen processing and presentation of endogenous antigen (GO:0019883)3.43448246
31neutrophil activation (GO:0042119)3.41669661
32antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.41609806
33pyrimidine ribonucleoside catabolic process (GO:0046133)3.40493537
34T cell selection (GO:0045058)3.40061844
35leukocyte aggregation (GO:0070486)3.37326351
36response to lipoprotein particle (GO:0055094)3.32018170
37positive regulation of tolerance induction (GO:0002645)3.31731521
38negative regulation of interleukin-12 production (GO:0032695)3.27252582
39regulation of T cell mediated cytotoxicity (GO:0001914)3.25901185
40negative regulation of lymphocyte mediated immunity (GO:0002707)3.25143865
41negative regulation of neurotransmitter transport (GO:0051589)3.24098055
42T cell migration (GO:0072678)3.22020961
43axon ensheathment (GO:0008366)3.21968752
44ensheathment of neurons (GO:0007272)3.21968752
45macrophage activation involved in immune response (GO:0002281)3.20400684
46creatine metabolic process (GO:0006600)3.19771319
47type I interferon signaling pathway (GO:0060337)3.19591818
48cellular response to type I interferon (GO:0071357)3.19591818
49granulocyte activation (GO:0036230)3.18370290
50positive regulation of T cell mediated cytotoxicity (GO:0001916)3.17217554
51myelination (GO:0042552)3.15938499
52protein localization to endosome (GO:0036010)3.14772505
53mast cell activation (GO:0045576)3.14190261
54response to type I interferon (GO:0034340)3.13419062
55regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)3.09147128
56positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO3.09147128
57myelin maintenance (GO:0043217)3.08886596
58antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.07788955
59negative regulation of cAMP-mediated signaling (GO:0043951)3.07756349
60regulation of tolerance induction (GO:0002643)3.06634761
61thymic T cell selection (GO:0045061)3.05624952
62Arp2/3 complex-mediated actin nucleation (GO:0034314)3.04204057
63virion attachment to host cell (GO:0019062)3.04028179
64adhesion of symbiont to host cell (GO:0044650)3.04028179
65glycerophospholipid catabolic process (GO:0046475)3.02723082
66regulation of natural killer cell mediated immunity (GO:0002715)3.02230686
67regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.02230686
68T-helper cell differentiation (GO:0042093)3.01997663
69CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)3.01997663
70immunoglobulin mediated immune response (GO:0016064)3.01610394
71positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.00808985
72amyloid precursor protein catabolic process (GO:0042987)2.97457715
73growth hormone receptor signaling pathway (GO:0060396)2.96794204
74regulation of leukocyte mediated cytotoxicity (GO:0001910)2.95543839
75actin nucleation (GO:0045010)2.92435830
76negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.90018984
77regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.89165629
78positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.89165629
79T cell receptor signaling pathway (GO:0050852)2.88807374
80regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.88540667
81response to redox state (GO:0051775)2.88380609
82positive regulation of leukocyte mediated cytotoxicity (GO:0001912)2.88102804
83positive regulation of granulocyte differentiation (GO:0030854)2.87350571
84photoreceptor cell differentiation (GO:0046530)2.86423643
85eye photoreceptor cell differentiation (GO:0001754)2.86423643
86regulation of alpha-beta T cell proliferation (GO:0046640)2.85462602
87membrane tubulation (GO:0097320)2.84941769
88alpha-beta T cell differentiation (GO:0046632)2.83808815
89regulation of B cell differentiation (GO:0045577)2.83301964
90negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.82608519
91negative regulation of T-helper cell differentiation (GO:0045623)2.82608519
92DNA deamination (GO:0045006)2.82461799
93antigen receptor-mediated signaling pathway (GO:0050851)2.82344869
94myeloid cell activation involved in immune response (GO:0002275)2.81633144
95regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.80024619
96alpha-beta T cell activation (GO:0046631)2.79805282
97CD4-positive, alpha-beta T cell differentiation (GO:0043367)2.78811342
98regulation of cell killing (GO:0031341)2.77697455
99positive regulation of mRNA catabolic process (GO:0061014)2.77174173
100negative regulation of inclusion body assembly (GO:0090084)2.77155328
101detection of other organism (GO:0098543)2.75659094
102T cell differentiation involved in immune response (GO:0002292)2.74502957
103alpha-beta T cell differentiation involved in immune response (GO:0002293)2.74502957
104alpha-beta T cell activation involved in immune response (GO:0002287)2.74502957
105neutrophil mediated immunity (GO:0002446)2.73425313
106dendritic cell migration (GO:0036336)2.73202619
107positive regulation of B cell differentiation (GO:0045579)2.73123983
108negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.71792429
109regulation of interleukin-12 biosynthetic process (GO:0045075)2.70207963
110negative regulation of adaptive immune response (GO:0002820)2.69998698
111positive regulation of natural killer cell mediated immunity (GO:0002717)2.68970867
112negative regulation of B cell proliferation (GO:0030889)2.68651830
113regulation of isotype switching to IgG isotypes (GO:0048302)2.67247124
114defense response to protozoan (GO:0042832)2.66016317
115positive regulation of cell killing (GO:0031343)2.65474490
116regulation of female gonad development (GO:2000194)2.57571910
117pathway-restricted SMAD protein phosphorylation (GO:0060389)2.56470136
118cellular response to growth hormone stimulus (GO:0071378)2.54284795
119adhesion of symbiont to host (GO:0044406)2.53365086
120fusion of sperm to egg plasma membrane (GO:0007342)2.53323392
121response to methylmercury (GO:0051597)2.49006946
122protein K11-linked deubiquitination (GO:0035871)2.48997497
123presynaptic membrane assembly (GO:0097105)2.46725912
124Rap protein signal transduction (GO:0032486)2.41993260
125asymmetric protein localization (GO:0008105)2.35733797
126amyloid precursor protein metabolic process (GO:0042982)2.34953431
127glycosylceramide metabolic process (GO:0006677)2.34522910
128peripheral nervous system axon ensheathment (GO:0032292)2.34172034
129myelination in peripheral nervous system (GO:0022011)2.34172034
130negative regulation of peptidyl-threonine phosphorylation (GO:0010801)2.32771543
131neutrophil activation involved in immune response (GO:0002283)2.31946309
132positive regulation of interleukin-17 production (GO:0032740)2.29211277
133platelet-derived growth factor receptor signaling pathway (GO:0048008)2.27064184
134membrane protein ectodomain proteolysis (GO:0006509)2.25330553
135erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.25253176
136L-phenylalanine catabolic process (GO:0006559)2.25253176
137positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.24698146
138multicellular organism reproduction (GO:0032504)2.24343592
139oligodendrocyte differentiation (GO:0048709)2.23709797
140positive regulation of mitochondrial calcium ion concentration (GO:0051561)2.21435980
141import into cell (GO:0098657)2.20677380
142intracellular pH reduction (GO:0051452)2.20086737
143regulation of extracellular matrix disassembly (GO:0010715)2.19796950
144ER overload response (GO:0006983)2.18816449
145membrane raft organization (GO:0031579)2.14683873
146nerve growth factor signaling pathway (GO:0038180)2.13323485
147opsonization (GO:0008228)2.10843833
148cellular ketone body metabolic process (GO:0046950)2.10310024
149cytoplasmic mRNA processing body assembly (GO:0033962)2.07078592
150positive regulation of toll-like receptor signaling pathway (GO:0034123)2.05372399
151pH reduction (GO:0045851)2.01797864
152regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022352.01357621
153establishment of endothelial barrier (GO:0061028)2.00797877
154negative regulation of exocytosis (GO:0045920)1.99929626
155presynaptic membrane organization (GO:0097090)1.99914726
156muscle cell migration (GO:0014812)1.97073115
157apical protein localization (GO:0045176)1.96461874
158negative regulation of protein localization to cell surface (GO:2000009)1.96399204
159peptidyl-tyrosine autophosphorylation (GO:0038083)1.95949133
160fatty-acyl-CoA biosynthetic process (GO:0046949)1.95754792
161regulation of mononuclear cell migration (GO:0071675)1.95723412
162cerebral cortex radially oriented cell migration (GO:0021799)1.95480171
163cholesterol biosynthetic process (GO:0006695)1.93498485
164regulation of energy homeostasis (GO:2000505)1.93440102
165positive regulation by symbiont of host defense response (GO:0052509)1.92705704
166modulation by symbiont of host defense response (GO:0052031)1.92705704
167modulation by organism of immune response of other organism involved in symbiotic interaction (GO:001.92705704
168modulation by organism of defense response of other organism involved in symbiotic interaction (GO:01.92705704
169positive regulation by organism of defense response of other organism involved in symbiotic interact1.92705704
170modulation by symbiont of host immune response (GO:0052553)1.92705704
171intracellular lipid transport (GO:0032365)1.91518330
172localization within membrane (GO:0051668)1.91377043
173ER-associated ubiquitin-dependent protein catabolic process (GO:0030433)1.91190642
174long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)1.90878553
175positive regulation of p38MAPK cascade (GO:1900745)1.89998192
176long-chain fatty acid biosynthetic process (GO:0042759)1.88642198
177signal peptide processing (GO:0006465)1.88414952
178phagocytosis, engulfment (GO:0006911)1.88324413
179regulation of lipoprotein metabolic process (GO:0050746)1.87043870
180regulation of RIG-I signaling pathway (GO:0039535)1.86599545
181reproduction (GO:0000003)1.86507504
182nucleotide transmembrane transport (GO:1901679)1.86419802
183keratan sulfate catabolic process (GO:0042340)1.86406090
184sperm capacitation (GO:0048240)1.85891573
185respiratory burst (GO:0045730)1.80986158
186membrane protein intracellular domain proteolysis (GO:0031293)1.80851845
187regulation of activation of Janus kinase activity (GO:0010533)1.80707999
188type B pancreatic cell development (GO:0003323)1.80106017
189ovulation cycle (GO:0042698)1.79460869
190myoblast migration (GO:0051451)1.77622429
191regulation of macrophage chemotaxis (GO:0010758)1.76986937
192positive regulation of vasculogenesis (GO:2001214)1.76679700
193blood vessel maturation (GO:0001955)1.76470104

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.14828829
2BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.87507169
3FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.57041659
4TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.54582444
5SMAD_19615063_ChIP-ChIP_OVARY_Human2.41632268
6IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.39943572
7MYB_26560356_Chip-Seq_TH2_Human2.14286801
8MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.03484097
9BP1_19119308_ChIP-ChIP_Hs578T_Human1.84204866
10CDX2_19796622_ChIP-Seq_MESCs_Mouse1.77300081
11LXR_22158963_ChIP-Seq_LIVER_Mouse1.77113730
12* GATA3_26560356_Chip-Seq_TH2_Human1.73690105
13Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.72393715
14IRF8_21731497_ChIP-ChIP_J774_Mouse1.66928619
15GBX2_23144817_ChIP-Seq_PC3_Human1.66576663
16STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.60104049
17GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.58262663
18LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.57010121
19CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.54666108
20MYB_26560356_Chip-Seq_TH1_Human1.53982388
21VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.49779171
22* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.49148493
23RXR_22158963_ChIP-Seq_LIVER_Mouse1.48856819
24SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.47952793
25IRF8_27001747_Chip-Seq_BMDM_Mouse1.44219087
26STAT4_19710469_ChIP-ChIP_TH1__Mouse1.42219508
27FOXO3_23340844_ChIP-Seq_DLD1_Human1.40593690
28NRF2_20460467_ChIP-Seq_MEFs_Mouse1.37948173
29NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.37948173
30SPI1_23127762_ChIP-Seq_K562_Human1.33633626
31SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.32590286
32RUNX_20019798_ChIP-Seq_JUKART_Human1.32212496
33* EP300_21415370_ChIP-Seq_HL-1_Mouse1.31413553
34GATA2_21666600_ChIP-Seq_HMVEC_Human1.30998204
35SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.29738579
36ZNF217_24962896_ChIP-Seq_MCF-7_Human1.28836386
37* SPI1_23547873_ChIP-Seq_NB4_Human1.28243492
38POU3F2_20337985_ChIP-ChIP_501MEL_Human1.27940077
39OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.27517610
40EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.26715281
41ZNF274_21170338_ChIP-Seq_K562_Hela1.26548823
42VDR_24787735_ChIP-Seq_THP-1_Human1.25688954
43ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.25532629
44NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.24105269
45RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.23480124
46SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.23382381
47FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.23240553
48RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.22802253
49ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.22019761
50CJUN_26792858_Chip-Seq_BT549_Human1.21280765
51FLI1_27457419_Chip-Seq_LIVER_Mouse1.20875774
52ESR1_20079471_ChIP-ChIP_T-47D_Human1.20111845
53MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.17508346
54PIAS1_25552417_ChIP-Seq_VCAP_Human1.16461990
55PCGF2_27294783_Chip-Seq_NPCs_Mouse1.16337975
56PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.15933237
57BCAT_22108803_ChIP-Seq_LS180_Human1.13950936
58EZH2_27294783_Chip-Seq_NPCs_Mouse1.13524811
59NFE2_27457419_Chip-Seq_LIVER_Mouse1.13372609
60STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.13225687
61TRIM28_21343339_ChIP-Seq_HEK293_Human1.13000987
62ER_23166858_ChIP-Seq_MCF-7_Human1.11687211
63PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.11594931
64NOTCH1_21737748_ChIP-Seq_TLL_Human1.10483779
65AR_21572438_ChIP-Seq_LNCaP_Human1.08428865
66* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.07996556
67SUZ12_27294783_Chip-Seq_NPCs_Mouse1.07621619
68MAF_26560356_Chip-Seq_TH1_Human1.07316696
69IRF8_22096565_ChIP-ChIP_GC-B_Human1.06902572
70TP63_23658742_ChIP-Seq_EP156T_Human1.06617833
71PCGF2_27294783_Chip-Seq_ESCs_Mouse1.06026012
72GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.05752434
73* PRDM14_20953172_ChIP-Seq_ESCs_Human1.05225499
74LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.04961593
75RXR_22108803_ChIP-Seq_LS180_Human1.04018274
76PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.03839076
77NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.03767972
78ELF1_17652178_ChIP-ChIP_JURKAT_Human1.03393543
79CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.02861480
80CBP_20019798_ChIP-Seq_JUKART_Human1.02672322
81IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.02672322
82* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.01557419
83SCL_19346495_ChIP-Seq_HPC-7_Human0.99985804
84UTX_26944678_Chip-Seq_JUKART_Human0.99965236
85* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.98716364
86* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.98688229
87UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.98557160
88TP53_16413492_ChIP-PET_HCT116_Human0.97526921
89PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.97049991
90IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.96021995
91PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.95390989
92MTF2_20144788_ChIP-Seq_MESCs_Mouse0.95368761
93MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.95135106
94STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.93256984
95WT1_19549856_ChIP-ChIP_CCG9911_Human0.93135784
96GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.92805495
97* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.92704420
98GATA1_19941826_ChIP-Seq_K562_Human0.92167817
99PPAR_26484153_Chip-Seq_NCI-H1993_Human0.91992169
100SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.91908175
101OCT4_21477851_ChIP-Seq_ESCs_Mouse0.91865356
102TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.90593415
103POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.90593415
104ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.90274572
105VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.90217327
106CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.89726158
107STAT3_23295773_ChIP-Seq_U87_Human0.89135747
108NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.88591786
109PPARA_22158963_ChIP-Seq_LIVER_Mouse0.88244404
110ZFP57_27257070_Chip-Seq_ESCs_Mouse0.87186844
111EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.86990961
112FOXA2_19822575_ChIP-Seq_HepG2_Human0.86828025
113NFIB_24661679_ChIP-Seq_LUNG_Mouse0.86771880
114FOXM1_26456572_ChIP-Seq_MCF-7_Human0.86617838
115* TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.86297066
116GATA2_19941826_ChIP-Seq_K562_Human0.86077360
117GATA3_26560356_Chip-Seq_TH1_Human0.85358555
118* TBX20_22080862_ChIP-Seq_HEART_Mouse0.85127596
119* TBX20_22328084_ChIP-Seq_HEART_Mouse0.85127596
120NR3C1_23031785_ChIP-Seq_PC12_Mouse0.85079137
121SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.84952748
122MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.84919565
123TP53_18474530_ChIP-ChIP_U2OS_Human0.84892667
124AR_25329375_ChIP-Seq_VCAP_Human0.84870124
125* SOX2_20726797_ChIP-Seq_SW620_Human0.84457110
126PU_27001747_Chip-Seq_BMDM_Mouse0.84373714
127FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.83627127
128WT1_25993318_ChIP-Seq_PODOCYTE_Human0.83337392
129ESR2_21235772_ChIP-Seq_MCF-7_Human0.83243709
130* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.82942051
131FLI1_21867929_ChIP-Seq_TH2_Mouse0.82712123
132P53_22387025_ChIP-Seq_ESCs_Mouse0.82580654
133RUNX1_22412390_ChIP-Seq_EML_Mouse0.82427841
134CRX_20693478_ChIP-Seq_RETINA_Mouse0.82297282
135TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.82192499
136SMAD3_21741376_ChIP-Seq_EPCs_Human0.81467212
137FOXA1_21572438_ChIP-Seq_LNCaP_Human0.81252341
138SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.80871899
139FOXA1_25552417_ChIP-Seq_VCAP_Human0.80529422
140CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.80506375
141AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.79389698
142TAF15_26573619_Chip-Seq_HEK293_Human0.79135521
143P300_19829295_ChIP-Seq_ESCs_Human0.79124191
144RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.78814633
145TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.78599279
146IRF1_19129219_ChIP-ChIP_H3396_Human0.78495479
147* GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.78390161
148EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.77990464
149PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.77940409
150PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.77935990
151CDX2_22108803_ChIP-Seq_LS180_Human0.77910006
152NANOG_18555785_Chip-Seq_ESCs_Mouse0.77691871
153TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.77591632
154VDR_22108803_ChIP-Seq_LS180_Human0.77580846
155ETV2_25802403_ChIP-Seq_MESCs_Mouse0.77351826
156JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.77143808
157* SMRT_27268052_Chip-Seq_Bcells_Human0.77125020
158BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.77016752
159P53_22127205_ChIP-Seq_FIBROBLAST_Human0.76188194
160TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.76125435
161SMAD4_21799915_ChIP-Seq_A2780_Human0.76069010
162GATA3_27048872_Chip-Seq_THYMUS_Human0.76057551
163MYB_21317192_ChIP-Seq_ERMYB_Mouse0.75938231
164SMAD4_21741376_ChIP-Seq_EPCs_Human0.75739403
165* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.75049952

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000920_abnormal_myelination3.60617856
2MP0005451_abnormal_body_composition3.32585629
3MP0006054_spinal_hemorrhage2.89520132
4MP0001800_abnormal_humoral_immune2.76769836
5MP0003763_abnormal_thymus_physiology2.55947573
6MP0005410_abnormal_fertilization2.54642868
7MP0008438_abnormal_cutaneous_collagen2.53876288
8MP0002877_abnormal_melanocyte_morpholog2.45804418
9MP0009840_abnormal_foam_cell2.39008326
10MP0006082_CNS_inflammation2.33494916
11MP0003690_abnormal_glial_cell2.33373458
12MP0002139_abnormal_hepatobiliary_system2.27426555
13MP0002163_abnormal_gland_morphology2.17898262
14MP0002166_altered_tumor_susceptibility2.09725744
15MP0003787_abnormal_imprinting2.07635579
16MP0002933_joint_inflammation2.05081769
17MP0004185_abnormal_adipocyte_glucose2.00523113
18MP0005058_abnormal_lysosome_morphology1.97052782
19MP0002009_preneoplasia1.96582407
20MP0003950_abnormal_plasma_membrane1.92718403
21MP0005171_absent_coat_pigmentation1.89346608
22MP0002837_dystrophic_cardiac_calcinosis1.89170727
23MP0004043_abnormal_pH_regulation1.87814647
24MP0003656_abnormal_erythrocyte_physiolo1.85798798
25MP0005379_endocrine/exocrine_gland_phen1.83701795
26MP0002405_respiratory_system_inflammati1.80506557
27MP0002398_abnormal_bone_marrow1.75954165
28MP0000716_abnormal_immune_system1.74182851
29MP0009333_abnormal_splenocyte_physiolog1.73548573
30MP0000343_altered_response_to1.72953372
31MP0001845_abnormal_inflammatory_respons1.68579682
32MP0002277_abnormal_respiratory_mucosa1.64306239
33MP0003646_muscle_fatigue1.63960295
34MP0000685_abnormal_immune_system1.60988649
35MP0008875_abnormal_xenobiotic_pharmacok1.60957442
36MP0003075_altered_response_to1.60660984
37MP0000689_abnormal_spleen_morphology1.59505432
38MP0003303_peritoneal_inflammation1.57717565
39MP0005365_abnormal_bile_salt1.55442049
40MP0001851_eye_inflammation1.54838957
41MP0000465_gastrointestinal_hemorrhage1.48242290
42MP0005387_immune_system_phenotype1.46830990
43MP0001790_abnormal_immune_system1.46830990
44MP0004381_abnormal_hair_follicle1.45456003
45MP0005310_abnormal_salivary_gland1.45344919
46MP0001533_abnormal_skeleton_physiology1.42943534
47MP0003866_abnormal_defecation1.42799145
48MP0003195_calcinosis1.41163139
49MP0005085_abnormal_gallbladder_physiolo1.41063345
50MP0002419_abnormal_innate_immunity1.39465020
51MP0004134_abnormal_chest_morphology1.38632418
52MP0000703_abnormal_thymus_morphology1.38592177
53MP0003724_increased_susceptibility_to1.38006889
54MP0002722_abnormal_immune_system1.37897832
55MP0010155_abnormal_intestine_physiology1.36823485
56MP0005360_urolithiasis1.34914589
57MP0009780_abnormal_chondrocyte_physiolo1.34817695
58MP0004130_abnormal_muscle_cell1.33644438
59MP0003436_decreased_susceptibility_to1.33211274
60MP0003172_abnormal_lysosome_physiology1.32170095
61MP0002006_tumorigenesis1.30987901
62MP0004947_skin_inflammation1.28858791
63MP0001502_abnormal_circadian_rhythm1.28351504
64MP0002693_abnormal_pancreas_physiology1.26684537
65MP0008469_abnormal_protein_level1.25350154
66MP0000579_abnormal_nail_morphology1.25039513
67MP0009384_cardiac_valve_regurgitation1.24973750
68MP0003045_fibrosis1.24900683
69MP0002429_abnormal_blood_cell1.24032898
70MP0003634_abnormal_glial_cell1.19898402
71MP0002118_abnormal_lipid_homeostasis1.19479422
72MP0004147_increased_porphyrin_level1.19256804
73MP0005464_abnormal_platelet_physiology1.18468375
74MP0003300_gastrointestinal_ulcer1.17419219
75MP0002254_reproductive_system_inflammat1.17260062
76MP0004510_myositis1.16477888
77MP0004145_abnormal_muscle_electrophysio1.15475387
78MP0003329_amyloid_beta_deposits1.15362144
79MP0003279_aneurysm1.14910328
80MP0005000_abnormal_immune_tolerance1.14778269
81MP0003191_abnormal_cellular_cholesterol1.11852921
82MP0004036_abnormal_muscle_relaxation1.11599408
83MP0003091_abnormal_cell_migration1.11150285
84MP0002138_abnormal_hepatobiliary_system1.10651606
85MP0002998_abnormal_bone_remodeling1.10536506
86MP0002148_abnormal_hypersensitivity_rea1.09154135
87MP0004883_abnormal_blood_vessel1.05224723
88MP0005075_abnormal_melanosome_morpholog1.05032593
89MP0003453_abnormal_keratinocyte_physiol1.03173043
90MP0003806_abnormal_nucleotide_metabolis1.02031327
91MP0002971_abnormal_brown_adipose0.99086754
92MP0002295_abnormal_pulmonary_circulatio0.99002502
93MP0000749_muscle_degeneration0.98341126
94MP0004885_abnormal_endolymph0.97944493
95MP0009785_altered_susceptibility_to0.96557771
96MP0001873_stomach_inflammation0.95464616
97MP0005671_abnormal_response_to0.95196976
98MP0001905_abnormal_dopamine_level0.94826480
99MP0005623_abnormal_meninges_morphology0.94534724
100MP0002653_abnormal_ependyma_morphology0.94075075
101MP0002928_abnormal_bile_duct0.93497400
102MP0000604_amyloidosis0.92343660
103MP0000462_abnormal_digestive_system0.92166020
104MP0005390_skeleton_phenotype0.91900386
105MP0002168_other_aberrant_phenotype0.90306851
106MP0010368_abnormal_lymphatic_system0.89148004
107MP0001986_abnormal_taste_sensitivity0.89106797
108MP0005164_abnormal_response_to0.88906212
109MP0004270_analgesia0.88726438
110MP0003252_abnormal_bile_duct0.88501984
111MP0008877_abnormal_DNA_methylation0.87823308
112MP0005084_abnormal_gallbladder_morpholo0.87679051
113MP0000013_abnormal_adipose_tissue0.86589212
114MP0001835_abnormal_antigen_presentation0.85115383
115MP0002876_abnormal_thyroid_physiology0.84991768
116MP0005166_decreased_susceptibility_to0.84598024
117MP0003828_pulmonary_edema0.83800365
118MP0001915_intracranial_hemorrhage0.83337392
119MP0005025_abnormal_response_to0.83118876
120MP0002102_abnormal_ear_morphology0.82820792
121MP0000569_abnormal_digit_pigmentation0.81898294
122MP0001853_heart_inflammation0.80899631
123MP0005503_abnormal_tendon_morphology0.80759901
124MP0009764_decreased_sensitivity_to0.80239209
125MP0009765_abnormal_xenobiotic_induced0.79732849
126MP0004233_abnormal_muscle_weight0.77575931
127MP0002723_abnormal_immune_serum0.77321650
128MP0001545_abnormal_hematopoietic_system0.75607507
129MP0005397_hematopoietic_system_phenotyp0.75607507
130MP0000639_abnormal_adrenal_gland0.75185258
131MP0003633_abnormal_nervous_system0.74403498
132MP0005167_abnormal_blood-brain_barrier0.73709394
133MP0003183_abnormal_peptide_metabolism0.71665393
134MP0000230_abnormal_systemic_arterial0.71611954
135MP0000003_abnormal_adipose_tissue0.70863730
136MP0005375_adipose_tissue_phenotype0.70540971
137MP0003795_abnormal_bone_structure0.70185587
138MP0002452_abnormal_antigen_presenting0.70000948
139MP0005535_abnormal_body_temperature0.69992419
140MP0009763_increased_sensitivity_to0.69951548
141MP0005174_abnormal_tail_pigmentation0.69619330
142MP0005332_abnormal_amino_acid0.69137580
143MP0002420_abnormal_adaptive_immunity0.67961422
144MP0001270_distended_abdomen0.67640415
145MP0003011_delayed_dark_adaptation0.67622536
146MP0000733_abnormal_muscle_development0.67608232
147MP0001501_abnormal_sleep_pattern0.67437392
148MP0005584_abnormal_enzyme/coenzyme_acti0.67399056
149MP0001819_abnormal_immune_cell0.67131164
150MP0001944_abnormal_pancreas_morphology0.65760711
151MP0004142_abnormal_muscle_tone0.64568729
152MP0008995_early_reproductive_senescence0.62730776
153MP0001919_abnormal_reproductive_system0.62505172
154MP0000015_abnormal_ear_pigmentation0.61148227
155MP0002136_abnormal_kidney_physiology0.60790479
156MP0002396_abnormal_hematopoietic_system0.60456277
157MP0003283_abnormal_digestive_organ0.60314243
158MP0001663_abnormal_digestive_system0.59980860
159MP0000249_abnormal_blood_vessel0.59818390
160MP0000372_irregular_coat_pigmentation0.58396015
161MP0002132_abnormal_respiratory_system0.57038940
162MP0001765_abnormal_ion_homeostasis0.56604752

Predicted human phenotypes

RankGene SetZ-score
1Stomatitis (HP:0010280)5.33646062
2Neurofibrillary tangles (HP:0002185)4.93796769
3Elevated erythrocyte sedimentation rate (HP:0003565)4.56158092
4Optic neuritis (HP:0100653)4.44759703
5Retrobulbar optic neuritis (HP:0100654)4.44759703
6Abnormality of T cell number (HP:0011839)4.44438777
7T lymphocytopenia (HP:0005403)4.41986944
8Myositis (HP:0100614)4.24613677
9Orchitis (HP:0100796)4.06331708
10Abnormal delayed hypersensitivity skin test (HP:0002963)4.03695597
11Eczematoid dermatitis (HP:0000976)4.02067924
12Recurrent bacterial skin infections (HP:0005406)3.83890344
13Recurrent abscess formation (HP:0002722)3.82440480
14Thyroiditis (HP:0100646)3.57999289
15Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)3.44898493
16Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.39705689
17Degeneration of the lateral corticospinal tracts (HP:0002314)3.39705689
18Autoimmune hemolytic anemia (HP:0001890)3.36047291
19Gastrointestinal infarctions (HP:0005244)3.35835982
20Cerebral inclusion bodies (HP:0100314)3.34994668
21Recurrent fungal infections (HP:0002841)3.33802115
22Male infertility (HP:0003251)3.31795665
23Pulmonary infiltrates (HP:0002113)3.28962239
24Abnormality of T cells (HP:0002843)3.24151528
25Severe combined immunodeficiency (HP:0004430)3.23609017
26Hematochezia (HP:0002573)3.23158757
27Leukocytosis (HP:0001974)3.17190614
28Encephalitis (HP:0002383)3.15216181
29Increased IgM level (HP:0003496)3.11489895
30Thickened helices (HP:0000391)3.10140500
31Mediastinal lymphadenopathy (HP:0100721)3.09011646
32Metaphyseal dysplasia (HP:0100255)3.07911678
33Chronic mucocutaneous candidiasis (HP:0002728)3.07793690
34Recurrent cutaneous fungal infections (HP:0011370)3.07793690
35Meningitis (HP:0001287)3.02267609
36Vasculitis (HP:0002633)2.97491225
37Abnormality of eosinophils (HP:0001879)2.95003879
38IgG deficiency (HP:0004315)2.94914171
39Recurrent skin infections (HP:0001581)2.89528270
40Clumsiness (HP:0002312)2.87577587
41Deep venous thrombosis (HP:0002625)2.85986162
42Keratoconjunctivitis sicca (HP:0001097)2.84506977
43Keratoconjunctivitis (HP:0001096)2.84214162
44Eosinophilia (HP:0001880)2.83624088
45Panhypogammaglobulinemia (HP:0003139)2.76981168
46Hemoptysis (HP:0002105)2.76059186
47Stridor (HP:0010307)2.75367473
48Increased neuronal autofluorescent lipopigment (HP:0002074)2.75013734
49Muscle fiber splitting (HP:0003555)2.71059329
50Intrahepatic cholestasis (HP:0001406)2.65586169
51Pancreatic cysts (HP:0001737)2.60106428
52Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.59477804
53Vascular tortuosity (HP:0004948)2.58156396
54Chronic obstructive pulmonary disease (HP:0006510)2.57784818
55Obstructive lung disease (HP:0006536)2.57784818
56Loss of speech (HP:0002371)2.57490898
57Arterial tortuosity (HP:0005116)2.55219668
58Increased cerebral lipofuscin (HP:0011813)2.53671342
59Joint swelling (HP:0001386)2.52936060
60Epiphyseal dysplasia (HP:0002656)2.52769902
61Pustule (HP:0200039)2.52377571
62Cerebral hemorrhage (HP:0001342)2.50891390
63Increased CSF protein (HP:0002922)2.48387703
64Premature skin wrinkling (HP:0100678)2.47531510
65Abnormality of T cell physiology (HP:0011840)2.47384392
66Exercise-induced myalgia (HP:0003738)2.46963091
67Malnutrition (HP:0004395)2.46902540
68Axonal loss (HP:0003447)2.46496886
69Amyloidosis (HP:0011034)2.45640871
70Autoimmune thrombocytopenia (HP:0001973)2.43464685
71Granulocytopenia (HP:0001913)2.42556939
72Episodic fever (HP:0001954)2.40793226
73Spondylolisthesis (HP:0003302)2.38641555
74Chest pain (HP:0100749)2.38393092
75Pulmonary embolism (HP:0002204)2.36910979
76Hypochromic microcytic anemia (HP:0004840)2.32313879
77Arterial thrombosis (HP:0004420)2.27484789
78Cholecystitis (HP:0001082)2.26862906
79Abnormal gallbladder physiology (HP:0012438)2.26862906
80Alveolar cell carcinoma (HP:0006519)2.24591524
81Gangrene (HP:0100758)2.24346230
82Recurrent viral infections (HP:0004429)2.24237018
83Large for gestational age (HP:0001520)2.23941852
84Hypoplastic ischia (HP:0003175)2.22264094
85Hypergammaglobulinemia (HP:0010702)2.19366758
86Combined immunodeficiency (HP:0005387)2.18364975
87Molar tooth sign on MRI (HP:0002419)2.16737328
88Abnormality of midbrain morphology (HP:0002418)2.16737328
89Supranuclear gaze palsy (HP:0000605)2.16371810
90Stomach cancer (HP:0012126)2.16339097
91Abnormal tarsal ossification (HP:0008369)2.16033449
92Neoplasm of the tracheobronchial system (HP:0100552)2.15928106
93Acute hepatic failure (HP:0006554)2.15763532
94Gowers sign (HP:0003391)2.15631280
95Prolonged bleeding time (HP:0003010)2.13521657
96Abnormality of macrophages (HP:0004311)2.12921334
97Aplasia involving bones of the upper limbs (HP:0009823)2.11759902
98Aplasia of the phalanges of the hand (HP:0009802)2.11759902
99Aplasia involving bones of the extremities (HP:0009825)2.11759902
100Disproportionate short-trunk short stature (HP:0003521)2.09271582
101Nonprogressive disorder (HP:0003680)2.06352329
102Dysostosis multiplex (HP:0000943)2.06223551
103Tetraparesis (HP:0002273)2.06141498
104Abnormality of the ischium (HP:0003174)2.05615257
105Keratitis (HP:0000491)2.05500670
106Abnormality of the corticospinal tract (HP:0002492)2.04930720
107Hyperlipoproteinemia (HP:0010980)2.03806832
108Anteriorly placed anus (HP:0001545)2.03776561
109Papilledema (HP:0001085)2.03646837
110Progressive neurologic deterioration (HP:0002344)2.03046483
111Hyperkalemia (HP:0002153)2.02190977
112Onion bulb formation (HP:0003383)2.01866776
113Gingivitis (HP:0000230)2.01209925
114Hypochromic anemia (HP:0001931)2.00383055
115Chronic diarrhea (HP:0002028)1.99149538
116Hypoproteinemia (HP:0003075)1.98277694
117Asymmetric septal hypertrophy (HP:0001670)1.98237984
118Retinal dysplasia (HP:0007973)1.97992145
119Barrel-shaped chest (HP:0001552)1.97949029
120Flat acetabular roof (HP:0003180)1.97722168
121Disinhibition (HP:0000734)1.97179458
122Abnormality of the phalanges of the 2nd finger (HP:0009541)1.96702576
123Abnormal auditory evoked potentials (HP:0006958)1.96366934
124Muscle fiber inclusion bodies (HP:0100299)1.96188328
125Anorexia (HP:0002039)1.95882989
126Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.95694433
127Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.94219965
128Spastic paraparesis (HP:0002313)1.93083528
129Hyporeflexia of lower limbs (HP:0002600)1.92335079
130Nemaline bodies (HP:0003798)1.91967962
131Ovoid vertebral bodies (HP:0003300)1.91228821
132Pancreatic fibrosis (HP:0100732)1.91220317
133Recurrent gram-negative bacterial infections (HP:0005420)1.91003663
134Steatorrhea (HP:0002570)1.90336938
135Recurrent bronchitis (HP:0002837)1.88414579
136Attenuation of retinal blood vessels (HP:0007843)1.87928430
137White forelock (HP:0002211)1.87428126
138Hypoplasia of the odontoid process (HP:0003311)1.87000536
139Paraparesis (HP:0002385)1.86960902
140Widely spaced teeth (HP:0000687)1.86767291
141Abnormality of aromatic amino acid family metabolism (HP:0004338)1.86609435
142Abnormality of B cell number (HP:0010975)1.85890730
143Increased IgE level (HP:0003212)1.85751725
144Slow saccadic eye movements (HP:0000514)1.85580110
145Polydipsia (HP:0001959)1.85204205
146Abnormal drinking behavior (HP:0030082)1.85204205
147Patchy hypopigmentation of hair (HP:0011365)1.83706825
148Muscle hypertrophy of the lower extremities (HP:0008968)1.83043040
149Abnormality of the pleura (HP:0002103)1.82437787
150Epistaxis (HP:0000421)1.81709325
151Lymphopenia (HP:0001888)1.81478972
152Generalized myoclonic seizures (HP:0002123)1.81164698
153Neoplasm of the adrenal cortex (HP:0100641)1.81132977
154True hermaphroditism (HP:0010459)1.80533311
155Abnormal rod and cone electroretinograms (HP:0008323)1.80426764
156Protuberant abdomen (HP:0001538)1.80348713
157Urinary glycosaminoglycan excretion (HP:0003541)1.80232273
158Mucopolysacchariduria (HP:0008155)1.80232273
159Polyneuropathy (HP:0001271)1.80100685
160Fat malabsorption (HP:0002630)1.79676326
161Abolished electroretinogram (ERG) (HP:0000550)1.79498605
162Urticaria (HP:0001025)1.78679747
163Premature rupture of membranes (HP:0001788)1.77797819
164Fair hair (HP:0002286)1.76302976
165Myocardial infarction (HP:0001658)1.75728444
166Abnormality of polysaccharide metabolism (HP:0011012)1.75436831
167Abnormality of glycosaminoglycan metabolism (HP:0004371)1.75436831
168Abnormality of mucopolysaccharide metabolism (HP:0011020)1.75436831
169Abnormality of the intrinsic pathway (HP:0010989)1.75254601
170Hypoplasia of the iris (HP:0007676)1.74232336
171Hemorrhage of the eye (HP:0011885)1.73365494
172Verrucae (HP:0200043)1.73282416
173Papilloma (HP:0012740)1.73282416
174Chronic bronchitis (HP:0004469)1.71315978
175Potter facies (HP:0002009)1.70178722
176Facial shape deformation (HP:0011334)1.70178722
177Vacuolated lymphocytes (HP:0001922)1.69765972
178Intention tremor (HP:0002080)1.69032725
179Xanthomatosis (HP:0000991)1.68345608
180Sensory axonal neuropathy (HP:0003390)1.67772422
181Gingival bleeding (HP:0000225)1.67771276
182Abnormality of glycolipid metabolism (HP:0010969)1.67389977
183Abnormality of liposaccharide metabolism (HP:0010968)1.67389977
184Abnormality of glycosphingolipid metabolism (HP:0004343)1.67389977
185Progressive visual loss (HP:0000529)1.65921775
186Abnormal gallbladder morphology (HP:0012437)1.65871601
187Dysmetria (HP:0001310)1.65780128
188Tetany (HP:0001281)1.65328237
189Exercise-induced muscle cramps (HP:0003710)1.64243080
190Spontaneous hematomas (HP:0007420)1.64014839

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK3.99466925
2FRK3.94308306
3TAOK33.53362994
4STK393.30149532
5EPHB13.20286951
6MAP4K13.18396295
7BMPR22.53709091
8MAP3K62.33163305
9PRPF4B2.24440198
10OXSR12.18299602
11MOS2.08081881
12ERN12.00252573
13DMPK1.98077892
14FES1.92490864
15MELK1.82793390
16BMPR1B1.77843035
17FGFR21.77610461
18MAP3K131.74233989
19WNK41.73993823
20LATS11.71573976
21PRKD31.71536041
22SYK1.69931176
23BLK1.63127182
24TEC1.61451537
25SIK31.55353155
26TYRO31.52379326
27LCK1.51855223
28IKBKB1.49778487
29INSRR1.48470988
30ZAP701.47383582
31CAMKK21.44291625
32MAP4K21.44043306
33BTK1.42140775
34KSR21.39172434
35GRK61.35049071
36STK101.34047835
37TRIM281.31400564
38HCK1.29013036
39ICK1.28948320
40PASK1.23288562
41NEK61.23085744
42AKT31.22097068
43MAPK71.22049830
44LYN1.20978468
45TNIK1.20851840
46PINK11.19941614
47EPHA31.19626040
48FGFR41.19313414
49SGK4941.18123676
50SGK2231.18123676
51PIK3CG1.15293070
52TNK21.15025473
53CDK191.13915948
54PRKCH1.13133828
55MET1.12535953
56PKN11.12189119
57ERBB41.08190535
58WNK11.07471577
59ADRBK21.07450230
60MAP3K141.05417075
61KIT1.03859480
62STK31.03381391
63MAPKAPK51.03301333
64GRK71.01684397
65CDK91.00677676
66JAK10.99912215
67PRKCQ0.95663865
68PAK60.94721529
69PDPK10.94621171
70MAP3K40.93915916
71CSK0.92555936
72HIPK20.92142524
73TRIB30.91650926
74YES10.91268642
75BCR0.88571189
76TRPM70.87065225
77ITK0.85253112
78NLK0.83336525
79IKBKE0.83304064
80SGK30.80750571
81BCKDK0.79873705
82CSNK1G10.78067525
83TGFBR10.77256759
84IRAK40.76593762
85DYRK20.75530340
86TYK20.75436291
87TGFBR20.74594211
88TAOK10.74578282
89PDK10.74216851
90GRK10.72412207
91BRAF0.72110256
92PIK3CA0.70874568
93CHUK0.70689746
94EPHA40.69916462
95JAK20.69297977
96RAF10.68880896
97LATS20.67717156
98PDGFRB0.67343426
99CSNK1G20.67318065
100CAMKK10.67266843
101PAK30.67188835
102SGK20.66807983
103ERBB30.66620462
104PTK2B0.66528668
105PRKD20.66298487
106IRAK20.66097110
107ACVR1B0.65795116
108RET0.65506542
109RIPK40.65264028
110JAK30.64859295
111PBK0.63134986
112MAPK130.63103822
113CSNK1A1L0.63002856
114MST40.62455617
115MAP3K10.61685047
116GSK3A0.60570945
117FGR0.59855369
118ARAF0.59327190
119MARK30.57473785
120PRKAA20.57050753
121ABL20.56978487
122PLK20.56758907
123PDK30.54463780
124PDK40.54463780
125MAPK150.54338501
126STK240.54017525
127TBK10.53667183
128IRAK10.52154701
129TIE10.52102303
130MUSK0.51985712
131SIK20.51692487
132CSF1R0.51538465
133MAP2K70.51180876
134STK110.51036135
135BRD40.50768931
136STK380.49657014
137PRKAA10.49298507
138CSNK1G30.48737784
139NUAK10.48229570
140ABL10.47774376
141PDK20.47341448
142PRKD10.47160827
143MAP3K30.47110624
144UHMK10.45244473
145ADRBK10.44844627
146MATK0.43844807
147ROCK20.43363404
148FLT30.43152649
149FGFR30.42990620
150MAP3K50.42755973
151MAP3K120.42349641
152TLK10.41250619
153DYRK1B0.40938024
154LRRK20.40191760
155MAP3K20.39603743
156FYN0.37789772
157PRKG10.37236006

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053402.90175007
2Allograft rejection_Homo sapiens_hsa053302.84248941
3Graft-versus-host disease_Homo sapiens_hsa053322.81581157
4Type I diabetes mellitus_Homo sapiens_hsa049402.74544370
5Autoimmune thyroid disease_Homo sapiens_hsa053202.70159379
6Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.29416566
7Steroid biosynthesis_Homo sapiens_hsa001002.25030100
8Sulfur metabolism_Homo sapiens_hsa009202.19211246
9Intestinal immune network for IgA production_Homo sapiens_hsa046721.99280754
10Fatty acid elongation_Homo sapiens_hsa000621.91198690
11Measles_Homo sapiens_hsa051621.82891740
12Hematopoietic cell lineage_Homo sapiens_hsa046401.80561201
13Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.79584129
14Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.73807287
15Ether lipid metabolism_Homo sapiens_hsa005651.71610727
16Dorso-ventral axis formation_Homo sapiens_hsa043201.69451901
17Antigen processing and presentation_Homo sapiens_hsa046121.68878646
18RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.51688779
19Asthma_Homo sapiens_hsa053101.50916819
20Nitrogen metabolism_Homo sapiens_hsa009101.40873280
21Renal cell carcinoma_Homo sapiens_hsa052111.39916851
22Viral myocarditis_Homo sapiens_hsa054161.37655102
23Circadian rhythm_Homo sapiens_hsa047101.33915448
24Legionellosis_Homo sapiens_hsa051341.32993910
25Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.27697447
26Lysosome_Homo sapiens_hsa041421.27211247
27Malaria_Homo sapiens_hsa051441.24625439
28Ovarian steroidogenesis_Homo sapiens_hsa049131.20894218
29Protein export_Homo sapiens_hsa030601.19986580
30Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.19121643
31Influenza A_Homo sapiens_hsa051641.18188435
32Staphylococcus aureus infection_Homo sapiens_hsa051501.18135320
33Sphingolipid metabolism_Homo sapiens_hsa006001.15308886
34Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.15138827
35Regulation of autophagy_Homo sapiens_hsa041401.13627251
36Fatty acid metabolism_Homo sapiens_hsa012121.13501443
37Collecting duct acid secretion_Homo sapiens_hsa049661.13095954
38Herpes simplex infection_Homo sapiens_hsa051681.11095371
39Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.09439465
40Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.09279723
41Histidine metabolism_Homo sapiens_hsa003401.08524752
42Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.06874572
43Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.03490061
44Osteoclast differentiation_Homo sapiens_hsa043801.02502163
45Linoleic acid metabolism_Homo sapiens_hsa005911.01537607
46African trypanosomiasis_Homo sapiens_hsa051431.00779891
47Complement and coagulation cascades_Homo sapiens_hsa046100.99220320
48alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.97980802
49Fatty acid biosynthesis_Homo sapiens_hsa000610.96310161
50Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.95391137
51Pancreatic cancer_Homo sapiens_hsa052120.94740174
52Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.92751150
53Primary bile acid biosynthesis_Homo sapiens_hsa001200.91758267
54Type II diabetes mellitus_Homo sapiens_hsa049300.90467035
55Sphingolipid signaling pathway_Homo sapiens_hsa040710.88752045
56Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.86198630
57Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.85868917
58Hepatitis B_Homo sapiens_hsa051610.83618737
59Chemokine signaling pathway_Homo sapiens_hsa040620.82594619
60Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.80701127
61Glycosaminoglycan degradation_Homo sapiens_hsa005310.80265756
62B cell receptor signaling pathway_Homo sapiens_hsa046620.79558792
63Adipocytokine signaling pathway_Homo sapiens_hsa049200.78179532
64Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.77796973
65Pertussis_Homo sapiens_hsa051330.77164309
66Fatty acid degradation_Homo sapiens_hsa000710.76770505
67Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.75518458
68Shigellosis_Homo sapiens_hsa051310.74498767
69Caffeine metabolism_Homo sapiens_hsa002320.74286076
70Rheumatoid arthritis_Homo sapiens_hsa053230.72867819
71Hepatitis C_Homo sapiens_hsa051600.72424656
72Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.71486763
73Leishmaniasis_Homo sapiens_hsa051400.70967877
74Arginine and proline metabolism_Homo sapiens_hsa003300.70203839
75Peroxisome_Homo sapiens_hsa041460.69837261
76Butanoate metabolism_Homo sapiens_hsa006500.69368821
77Maturity onset diabetes of the young_Homo sapiens_hsa049500.69176322
78Choline metabolism in cancer_Homo sapiens_hsa052310.67489136
79Propanoate metabolism_Homo sapiens_hsa006400.67178809
80Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.65491163
81Phagosome_Homo sapiens_hsa041450.65484040
82Leukocyte transendothelial migration_Homo sapiens_hsa046700.65375406
83Toxoplasmosis_Homo sapiens_hsa051450.64616103
84Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.64034287
85Regulation of actin cytoskeleton_Homo sapiens_hsa048100.62994326
86MAPK signaling pathway_Homo sapiens_hsa040100.62744697
87Other glycan degradation_Homo sapiens_hsa005110.61972405
88Ras signaling pathway_Homo sapiens_hsa040140.60953667
89Pentose and glucuronate interconversions_Homo sapiens_hsa000400.60672076
90Endocytosis_Homo sapiens_hsa041440.60489601
91TGF-beta signaling pathway_Homo sapiens_hsa043500.60261410
92Insulin resistance_Homo sapiens_hsa049310.60224728
93ABC transporters_Homo sapiens_hsa020100.59632724
94Pancreatic secretion_Homo sapiens_hsa049720.59341065
95Toll-like receptor signaling pathway_Homo sapiens_hsa046200.59071536
96Jak-STAT signaling pathway_Homo sapiens_hsa046300.58171442
97PPAR signaling pathway_Homo sapiens_hsa033200.57389446
98VEGF signaling pathway_Homo sapiens_hsa043700.57274985
99Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.57119575
100Phosphatidylinositol signaling system_Homo sapiens_hsa040700.55481028
101Focal adhesion_Homo sapiens_hsa045100.54963286
102Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.54382379
103Phospholipase D signaling pathway_Homo sapiens_hsa040720.53609059
104TNF signaling pathway_Homo sapiens_hsa046680.53404524
105Inositol phosphate metabolism_Homo sapiens_hsa005620.53073014
106Arginine biosynthesis_Homo sapiens_hsa002200.53027270
107Carbohydrate digestion and absorption_Homo sapiens_hsa049730.52959179
108Long-term depression_Homo sapiens_hsa047300.52572056
109NF-kappa B signaling pathway_Homo sapiens_hsa040640.52117622
110Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.51819079
111FoxO signaling pathway_Homo sapiens_hsa040680.51566473
112ECM-receptor interaction_Homo sapiens_hsa045120.51423719
113Transcriptional misregulation in cancer_Homo sapiens_hsa052020.50934918
114ErbB signaling pathway_Homo sapiens_hsa040120.50735519
115Phototransduction_Homo sapiens_hsa047440.50199253
116Non-small cell lung cancer_Homo sapiens_hsa052230.49257019
117Vitamin B6 metabolism_Homo sapiens_hsa007500.48905653
118T cell receptor signaling pathway_Homo sapiens_hsa046600.48443387
119Axon guidance_Homo sapiens_hsa043600.48272404
120Vascular smooth muscle contraction_Homo sapiens_hsa042700.47802467
121Prolactin signaling pathway_Homo sapiens_hsa049170.47675829
122Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.47604477
123Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.47399454
124beta-Alanine metabolism_Homo sapiens_hsa004100.46840734
125Steroid hormone biosynthesis_Homo sapiens_hsa001400.46468637
126Tuberculosis_Homo sapiens_hsa051520.46060999
127Salmonella infection_Homo sapiens_hsa051320.45716623
128Apoptosis_Homo sapiens_hsa042100.45551469
129SNARE interactions in vesicular transport_Homo sapiens_hsa041300.45287069
130Protein digestion and absorption_Homo sapiens_hsa049740.44040902
131Glycerophospholipid metabolism_Homo sapiens_hsa005640.43976734
132AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.43656660
133NOD-like receptor signaling pathway_Homo sapiens_hsa046210.43558224
134cAMP signaling pathway_Homo sapiens_hsa040240.43389808
135Acute myeloid leukemia_Homo sapiens_hsa052210.43325403
136Prostate cancer_Homo sapiens_hsa052150.43273253
137Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.42917687
138Platelet activation_Homo sapiens_hsa046110.41629751
139Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.41001216
140Arachidonic acid metabolism_Homo sapiens_hsa005900.40889114
141Olfactory transduction_Homo sapiens_hsa047400.38177598
142Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.37860723
143Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.37011669
144Neurotrophin signaling pathway_Homo sapiens_hsa047220.33752283
145Epstein-Barr virus infection_Homo sapiens_hsa051690.33442828
146Renin secretion_Homo sapiens_hsa049240.32006119

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »