HIC2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)5.01275305
2nuclear pore organization (GO:0006999)5.00331964
3viral transcription (GO:0019083)4.88165434
4mitotic metaphase plate congression (GO:0007080)4.76773995
5translational termination (GO:0006415)4.75711115
6ribosomal small subunit assembly (GO:0000028)4.73390619
7paraxial mesoderm development (GO:0048339)4.68029860
8protein localization to kinetochore (GO:0034501)4.54641374
9regulation of posttranscriptional gene silencing (GO:0060147)4.47146657
10regulation of gene silencing by miRNA (GO:0060964)4.47146657
11regulation of gene silencing by RNA (GO:0060966)4.47146657
12pre-miRNA processing (GO:0031054)4.35813406
13mitotic sister chromatid segregation (GO:0000070)4.32193000
14ribosomal small subunit biogenesis (GO:0042274)4.31899315
15DNA replication checkpoint (GO:0000076)4.28510538
16maturation of SSU-rRNA (GO:0030490)4.13738333
17metaphase plate congression (GO:0051310)4.09349466
18nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.08866404
19DNA replication-dependent nucleosome assembly (GO:0006335)4.04841305
20DNA replication-dependent nucleosome organization (GO:0034723)4.04841305
21protein localization to chromosome, centromeric region (GO:0071459)4.03020406
22mitotic nuclear envelope disassembly (GO:0007077)4.01815113
23translational elongation (GO:0006414)3.93901177
24histone H4-K12 acetylation (GO:0043983)3.93759963
25regulation of nuclear cell cycle DNA replication (GO:0033262)3.89372991
26mitotic chromosome condensation (GO:0007076)3.88540970
27regulation of hippo signaling (GO:0035330)3.84133009
28sister chromatid segregation (GO:0000819)3.82751959
29pore complex assembly (GO:0046931)3.81254313
30DNA replication initiation (GO:0006270)3.78205712
31cellular protein complex disassembly (GO:0043624)3.78155460
32translational initiation (GO:0006413)3.77607833
33SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.77440550
34regulation of DNA methylation (GO:0044030)3.76389275
35membrane disassembly (GO:0030397)3.73554398
36nuclear envelope disassembly (GO:0051081)3.73554398
37regulation of telomere maintenance via telomerase (GO:0032210)3.70726681
38regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.70143446
39cotranslational protein targeting to membrane (GO:0006613)3.70137511
40kinetochore assembly (GO:0051382)3.67556493
41regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.67452333
42protein complex disassembly (GO:0043241)3.66361869
43kinetochore organization (GO:0051383)3.65595045
44negative regulation of histone methylation (GO:0031061)3.64211478
45viral life cycle (GO:0019058)3.63186305
46protein targeting to ER (GO:0045047)3.62901514
47heterochromatin organization (GO:0070828)3.61833053
48DNA topological change (GO:0006265)3.59906419
49histone H2A monoubiquitination (GO:0035518)3.59079007
50protein K6-linked ubiquitination (GO:0085020)3.57129885
51regulation of spindle organization (GO:0090224)3.57091644
52ribosomal large subunit biogenesis (GO:0042273)3.51190694
53regulation of translational fidelity (GO:0006450)3.50597961
54establishment of protein localization to endoplasmic reticulum (GO:0072599)3.48870015
55regulation of double-strand break repair via homologous recombination (GO:0010569)3.46795609
56ribosome biogenesis (GO:0042254)3.46047960
57macromolecular complex disassembly (GO:0032984)3.45726703
58meiotic chromosome segregation (GO:0045132)3.44588528
59establishment of chromosome localization (GO:0051303)3.37274730
60notochord development (GO:0030903)3.37267145
61protein localization to endoplasmic reticulum (GO:0070972)3.34067316
62maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.33989595
63nucleobase biosynthetic process (GO:0046112)3.33809668
64histone H4-K8 acetylation (GO:0043982)3.31899975
65histone H4-K5 acetylation (GO:0043981)3.31899975
66protein localization to chromosome (GO:0034502)3.30896090
67microtubule depolymerization (GO:0007019)3.30757878
68regulation of RNA export from nucleus (GO:0046831)3.28374792
69telomere maintenance via semi-conservative replication (GO:0032201)3.27655544
70regulation of histone H3-K9 methylation (GO:0051570)3.27436653
71positive regulation of chromosome segregation (GO:0051984)3.26355894
72regulation of histone H3-K4 methylation (GO:0051569)3.26166244
73purine nucleobase biosynthetic process (GO:0009113)3.25973199
74DNA duplex unwinding (GO:0032508)3.23312286
75DNA geometric change (GO:0032392)3.22556808
76DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla3.21625834
77negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.20644555
78ribonucleoprotein complex biogenesis (GO:0022613)3.20240284
79DNA unwinding involved in DNA replication (GO:0006268)3.19825096
80DNA replication-independent nucleosome organization (GO:0034724)3.19217098
81DNA replication-independent nucleosome assembly (GO:0006336)3.19217098
82regulation of helicase activity (GO:0051095)3.18903159
83chromosome condensation (GO:0030261)3.18359263
84DNA damage response, signal transduction resulting in transcription (GO:0042772)3.14693059
85chromosome segregation (GO:0007059)3.14481080
86spindle checkpoint (GO:0031577)3.13540256
87chromatin remodeling at centromere (GO:0031055)3.13350323
88inner cell mass cell proliferation (GO:0001833)3.12674033
89ribosome assembly (GO:0042255)3.11960370
90chromatin assembly (GO:0031497)3.11770189
91regulation of mitotic spindle organization (GO:0060236)3.11489567
92somatic hypermutation of immunoglobulin genes (GO:0016446)3.08180941
93somatic diversification of immune receptors via somatic mutation (GO:0002566)3.08180941
94regulation of chromosome segregation (GO:0051983)3.07678618
95regulation of double-strand break repair (GO:2000779)3.07510852
96chromatin assembly or disassembly (GO:0006333)3.07189209
97dosage compensation (GO:0007549)3.06805312
98negative regulation of chromosome segregation (GO:0051985)3.06485297
99CENP-A containing nucleosome assembly (GO:0034080)3.06443840
100negative regulation of RNA splicing (GO:0033119)3.04381642
101trophectodermal cell differentiation (GO:0001829)3.02924021
102nuclear-transcribed mRNA catabolic process (GO:0000956)3.02881471
103nucleosome disassembly (GO:0006337)3.02859220
104protein-DNA complex disassembly (GO:0032986)3.02859220
105regulation of gene expression by genetic imprinting (GO:0006349)3.02003590
106positive regulation of mitotic sister chromatid separation (GO:1901970)3.00883230
107positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.00883230
108positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.00883230
109attachment of spindle microtubules to kinetochore (GO:0008608)2.99728453
110regulation of histone methylation (GO:0031060)2.99263193
111replication fork processing (GO:0031297)2.98481209
112regulation of centrosome cycle (GO:0046605)2.98355947
113formation of translation preinitiation complex (GO:0001731)2.97678524
114spindle assembly checkpoint (GO:0071173)2.97469685
115regulation of sister chromatid cohesion (GO:0007063)2.96190690
116regulation of gene silencing (GO:0060968)2.95558100
117DNA strand elongation involved in DNA replication (GO:0006271)2.94227168
118regulation of mitotic metaphase/anaphase transition (GO:0030071)2.93788246
119negative regulation of mitotic sister chromatid separation (GO:2000816)2.93284934
120negative regulation of mitotic sister chromatid segregation (GO:0033048)2.93284934
121negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.93284934
122negative regulation of sister chromatid segregation (GO:0033046)2.93284934
123maturation of 5.8S rRNA (GO:0000460)2.92837929
124homocysteine metabolic process (GO:0050667)2.92664701
125mitotic spindle checkpoint (GO:0071174)2.92495351
126mRNA transport (GO:0051028)2.91728444
127mitotic spindle assembly checkpoint (GO:0007094)2.91216766
128mRNA catabolic process (GO:0006402)2.90212503
129histone exchange (GO:0043486)2.89793243
130regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.88503563
131DNA strand elongation (GO:0022616)2.87237567
132negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.86460736
133IMP biosynthetic process (GO:0006188)2.85742735
134nuclear envelope organization (GO:0006998)2.85102950
135DNA packaging (GO:0006323)2.85021410
136mitotic sister chromatid cohesion (GO:0007064)2.84048332
137mitotic recombination (GO:0006312)2.80133672
138resolution of meiotic recombination intermediates (GO:0000712)2.79699837
139RNA catabolic process (GO:0006401)2.79270189
140ATP-dependent chromatin remodeling (GO:0043044)2.78733542
141telomere maintenance via recombination (GO:0000722)2.77448336
142negative regulation of mRNA processing (GO:0050686)2.75446869
143protein complex localization (GO:0031503)2.73046113
144viral mRNA export from host cell nucleus (GO:0046784)2.72340393
145synapsis (GO:0007129)2.67138439
146genetic imprinting (GO:0071514)2.66450160
147translation (GO:0006412)2.65460423
148negative regulation of mRNA metabolic process (GO:1903312)2.63620216
149primitive streak formation (GO:0090009)2.62153200
150regulation of nucleobase-containing compound transport (GO:0032239)2.61976330

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.77012857
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.98325745
3E2F4_17652178_ChIP-ChIP_JURKAT_Human3.69467190
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.51242442
5FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.43923975
6MYC_19079543_ChIP-ChIP_MESCs_Mouse2.91971771
7KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.89058714
8KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.89058714
9KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.89058714
10KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.70564122
11MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.64704012
12* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.56406394
13SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.55970307
14TP63_19390658_ChIP-ChIP_HaCaT_Human2.55410612
15SALL1_21062744_ChIP-ChIP_HESCs_Human2.45537032
16POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.38264344
17NANOG_18555785_ChIP-Seq_MESCs_Mouse2.35750550
18NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.31293708
19EZH2_22144423_ChIP-Seq_EOC_Human2.20437446
20MYC_18358816_ChIP-ChIP_MESCs_Mouse2.20254838
21NELFA_20434984_ChIP-Seq_ESCs_Mouse2.16272490
22MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.15776574
23POU5F1_18555785_ChIP-Seq_MESCs_Mouse2.11261488
24E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.10414875
25CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.08249259
26* NACC1_18358816_ChIP-ChIP_MESCs_Mouse2.06454130
27KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.00965483
28MYCN_18555785_ChIP-Seq_MESCs_Mouse1.96662799
29AR_21909140_ChIP-Seq_LNCAP_Human1.95220268
30E2F1_21310950_ChIP-Seq_MCF-7_Human1.94002381
31TCF3_18692474_ChIP-Seq_MESCs_Mouse1.92190445
32EST1_17652178_ChIP-ChIP_JURKAT_Human1.91214670
33SOX2_18555785_ChIP-Seq_MESCs_Mouse1.88519580
34EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.87889404
35TCF3_18692474_ChIP-Seq_MEFs_Mouse1.83797715
36ETS1_20019798_ChIP-Seq_JURKAT_Human1.83234973
37MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.82826550
38CREB1_15753290_ChIP-ChIP_HEK293T_Human1.82077850
39JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.79445017
40SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.77484708
41EGR1_19374776_ChIP-ChIP_THP-1_Human1.77442518
42POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.75460244
43XRN2_22483619_ChIP-Seq_HELA_Human1.73309475
44SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.70213238
45YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.66813546
46TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.64387776
47SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.63828848
48NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.62019069
49* ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.58389855
50ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.57343911
51YY1_21170310_ChIP-Seq_MESCs_Mouse1.56451788
52HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.56041174
53KDM5A_27292631_Chip-Seq_BREAST_Human1.55794612
54E2F1_18555785_ChIP-Seq_MESCs_Mouse1.51916495
55NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.51569019
56* NANOG_21062744_ChIP-ChIP_HESCs_Human1.49537028
57STAT3_1855785_ChIP-Seq_MESCs_Mouse1.47568481
58TTF2_22483619_ChIP-Seq_HELA_Human1.45410151
59GABP_17652178_ChIP-ChIP_JURKAT_Human1.44573301
60THAP11_20581084_ChIP-Seq_MESCs_Mouse1.44214255
61VDR_23849224_ChIP-Seq_CD4+_Human1.43894495
62MYC_22102868_ChIP-Seq_BL_Human1.43010013
63* NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.42055233
64NCOR1_26117541_ChIP-Seq_K562_Human1.37622336
65* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.35456663
66* KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.34968323
67FOXP3_21729870_ChIP-Seq_TREG_Human1.34639417
68GABP_19822575_ChIP-Seq_HepG2_Human1.33532866
69* POU5F1_16518401_ChIP-PET_MESCs_Mouse1.30023018
70DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.29504449
71KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.29204345
72CIITA_25753668_ChIP-Seq_RAJI_Human1.28859202
73SOX2_18692474_ChIP-Seq_MESCs_Mouse1.25428026
74* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.23586710
75PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.21317521
76TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.18867407
77* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.17474981
78RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.17307754
79DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.17286811
80POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.16869993
81DCP1A_22483619_ChIP-Seq_HELA_Human1.15986912
82RBPJ_22232070_ChIP-Seq_NCS_Mouse1.15975290
83SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.15350447
84ZFX_18555785_ChIP-Seq_MESCs_Mouse1.12486768
85* NANOG_18692474_ChIP-Seq_MESCs_Mouse1.10760810
86* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.09274971
87NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.09244872
88NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.08872785
89* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.08563248
90HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.07143329
91KAP1_27257070_Chip-Seq_ESCs_Mouse1.05876608
92* GATA1_26923725_Chip-Seq_HPCs_Mouse1.03558451
93SOX2_18692474_ChIP-Seq_MEFs_Mouse1.02869812
94SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.01059285
95POU5F1_16153702_ChIP-ChIP_HESCs_Human1.00806484
96ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.00016044
97CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.99885077
98* POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.99847663
99ELF1_17652178_ChIP-ChIP_JURKAT_Human0.99070667
100PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.98805093
101ZNF263_19887448_ChIP-Seq_K562_Human0.97910351
102ESR1_15608294_ChIP-ChIP_MCF-7_Human0.97649387
103NANOG_16153702_ChIP-ChIP_HESCs_Human0.97012246
104TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.96502256
105HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.96111112
106TFEB_21752829_ChIP-Seq_HELA_Human0.95314260
107SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.95115547
108PADI4_21655091_ChIP-ChIP_MCF-7_Human0.95019082
109PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.94214853
110E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.93849187
111* NANOG_18692474_ChIP-Seq_MEFs_Mouse0.93812556
112SOX2_16153702_ChIP-ChIP_HESCs_Human0.92622376
113HOXB4_20404135_ChIP-ChIP_EML_Mouse0.92040952
114* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.91947320
115OCT4_18692474_ChIP-Seq_MEFs_Mouse0.91279758
116* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.91249002
117ELK1_19687146_ChIP-ChIP_HELA_Human0.88753519
118HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.88158136
119MYC_18940864_ChIP-ChIP_HL60_Human0.86964146
120TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.83672349
121FOXP1_21924763_ChIP-Seq_HESCs_Human0.81350986
122* ZFP281_18757296_ChIP-ChIP_E14_Mouse0.76652976
123SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.76514576
124EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.75243267
125CHD1_26751641_Chip-Seq_LNCaP_Human0.73639576

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.40894151
2MP0003111_abnormal_nucleus_morphology4.10281217
3MP0008057_abnormal_DNA_replication3.97683676
4MP0004957_abnormal_blastocyst_morpholog3.62944553
5MP0010094_abnormal_chromosome_stability3.59042566
6MP0003077_abnormal_cell_cycle3.53225507
7MP0003123_paternal_imprinting2.90394308
8MP0008058_abnormal_DNA_repair2.86114968
9MP0002653_abnormal_ependyma_morphology2.79098986
10MP0003890_abnormal_embryonic-extraembry2.60203380
11MP0003121_genomic_imprinting2.46818487
12MP0009379_abnormal_foot_pigmentation2.37776776
13MP0006292_abnormal_olfactory_placode2.31802438
14MP0000350_abnormal_cell_proliferation2.29597766
15MP0008007_abnormal_cellular_replicative2.29260170
16MP0001730_embryonic_growth_arrest2.29166760
17MP0008877_abnormal_DNA_methylation2.27418764
18MP0001672_abnormal_embryogenesis/_devel2.23292376
19MP0005380_embryogenesis_phenotype2.23292376
20MP0008932_abnormal_embryonic_tissue2.03919982
21MP0002085_abnormal_embryonic_tissue2.02227709
22MP0002084_abnormal_developmental_patter2.01467531
23MP0004264_abnormal_extraembryonic_tissu1.96779330
24MP0003984_embryonic_growth_retardation1.96346350
25MP0002088_abnormal_embryonic_growth/wei1.92963396
26MP0001697_abnormal_embryo_size1.90509698
27MP0002086_abnormal_extraembryonic_tissu1.82020799
28MP0010030_abnormal_orbit_morphology1.79643466
29MP0003119_abnormal_digestive_system1.78891676
30MP0001346_abnormal_lacrimal_gland1.74817587
31MP0004147_increased_porphyrin_level1.74538827
32MP0001293_anophthalmia1.73163233
33MP0003718_maternal_effect1.71957666
34MP0003787_abnormal_imprinting1.70608387
35MP0010352_gastrointestinal_tract_polyps1.68540638
36MP0004197_abnormal_fetal_growth/weight/1.68167925
37MP0005076_abnormal_cell_differentiation1.66862564
38MP0010307_abnormal_tumor_latency1.60549134
39MP0003786_premature_aging1.59294803
40MP0003315_abnormal_perineum_morphology1.55437581
41MP0000678_abnormal_parathyroid_gland1.55002381
42MP0002080_prenatal_lethality1.52148731
43MP0003937_abnormal_limbs/digits/tail_de1.50069408
44MP0003941_abnormal_skin_development1.49663053
45MP0003567_abnormal_fetal_cardiomyocyte1.47444831
46MP0003122_maternal_imprinting1.38446599
47MP0002210_abnormal_sex_determination1.32372454
48MP0003942_abnormal_urinary_system1.32189971
49MP0000490_abnormal_crypts_of1.30827799
50MP0000631_abnormal_neuroendocrine_gland1.30148217
51MP0009053_abnormal_anal_canal1.24716731
52MP0002938_white_spotting1.22959397
53MP0004133_heterotaxia1.21077575
54MP0000537_abnormal_urethra_morphology1.18380595
55MP0009697_abnormal_copulation1.18363296
56MP0000566_synostosis1.18252003
57MP0000313_abnormal_cell_death1.15369940
58MP0001286_abnormal_eye_development1.14980479
59MP0001529_abnormal_vocalization1.14589718
60MP0001145_abnormal_male_reproductive1.13501789
61MP0000647_abnormal_sebaceous_gland1.12422878
62MP0000428_abnormal_craniofacial_morphol1.11149080
63MP0003755_abnormal_palate_morphology1.10936302
64MP0006035_abnormal_mitochondrial_morpho1.09796167
65MP0000432_abnormal_head_morphology1.09674116
66MP0009703_decreased_birth_body1.09511749
67MP0003861_abnormal_nervous_system1.09283911
68MP0005257_abnormal_intraocular_pressure1.07494080
69MP0003935_abnormal_craniofacial_develop1.06587021
70MP0009672_abnormal_birth_weight1.05973087
71MP0003698_abnormal_male_reproductive1.05843731
72MP0002111_abnormal_tail_morphology1.04431274
73MP0003938_abnormal_ear_development1.04406477
74MP0001849_ear_inflammation1.03239007
75MP0002396_abnormal_hematopoietic_system1.01496320
76MP0002249_abnormal_larynx_morphology1.01285574
77MP0002161_abnormal_fertility/fecundity1.01216920
78MP0002697_abnormal_eye_size1.01210284
79MP0001929_abnormal_gametogenesis1.00501378
80MP0000653_abnormal_sex_gland0.99654028
81MP0002092_abnormal_eye_morphology0.94652800
82MP0003705_abnormal_hypodermis_morpholog0.93276539
83MP0001119_abnormal_female_reproductive0.92238926
84MP0002102_abnormal_ear_morphology0.92168385
85MP0002019_abnormal_tumor_incidence0.87108952
86MP0005451_abnormal_body_composition0.86760951
87MP0002127_abnormal_cardiovascular_syste0.86686523
88MP0005499_abnormal_olfactory_system0.86678029
89MP0005394_taste/olfaction_phenotype0.86678029
90MP0003136_yellow_coat_color0.86394895
91MP0002233_abnormal_nose_morphology0.85937037
92MP0002277_abnormal_respiratory_mucosa0.85847077
93MP0005377_hearing/vestibular/ear_phenot0.85218250
94MP0003878_abnormal_ear_physiology0.85218250
95MP0008995_early_reproductive_senescence0.84434264
96MP0008789_abnormal_olfactory_epithelium0.82473795
97MP0003283_abnormal_digestive_organ0.81511915
98MP0005646_abnormal_pituitary_gland0.81019846
99MP0002234_abnormal_pharynx_morphology0.79731576
100MP0000778_abnormal_nervous_system0.78836534
101MP0002152_abnormal_brain_morphology0.78552327
102MP0000516_abnormal_urinary_system0.77729580
103MP0005367_renal/urinary_system_phenotyp0.77729580
104MP0003936_abnormal_reproductive_system0.75686330
105MP0001915_intracranial_hemorrhage0.75614647
106MP0002114_abnormal_axial_skeleton0.74883476
107MP0002081_perinatal_lethality0.74808855
108MP0002116_abnormal_craniofacial_bone0.73936265
109MP0002160_abnormal_reproductive_system0.73883127
110MP0002925_abnormal_cardiovascular_devel0.73738904
111MP0005384_cellular_phenotype0.73184660
112MP0003385_abnormal_body_wall0.73030628
113MP0004185_abnormal_adipocyte_glucose0.72671658
114MP0004233_abnormal_muscle_weight0.71141210
115MP0003115_abnormal_respiratory_system0.69807038
116MP0002163_abnormal_gland_morphology0.69444591
117MP0005621_abnormal_cell_physiology0.68951663
118MP0001188_hyperpigmentation0.68855499
119MP0005187_abnormal_penis_morphology0.68272071
120MP0008770_decreased_survivor_rate0.67918149
121MP0003699_abnormal_female_reproductive0.67727051
122MP0000049_abnormal_middle_ear0.66643314
123MP0002932_abnormal_joint_morphology0.66543687
124MP0005410_abnormal_fertilization0.65124098
125MP0002089_abnormal_postnatal_growth/wei0.60655681

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)4.73206866
2Reticulocytopenia (HP:0001896)4.44425351
3Chromsome breakage (HP:0040012)4.43996886
4Abnormality of the labia minora (HP:0012880)4.23721420
5Truncus arteriosus (HP:0001660)4.17313437
6Ependymoma (HP:0002888)3.99305398
7Birth length less than 3rd percentile (HP:0003561)3.96205715
8Abnormality of cells of the erythroid lineage (HP:0012130)3.84235057
9Patellar aplasia (HP:0006443)3.82558988
10Breast hypoplasia (HP:0003187)3.69498764
11Abnormal number of erythroid precursors (HP:0012131)3.64906482
12Aplasia/Hypoplasia of the patella (HP:0006498)3.54660065
13Shawl scrotum (HP:0000049)3.49916367
14Impulsivity (HP:0100710)3.46926249
15Rib fusion (HP:0000902)3.33508895
16Homocystinuria (HP:0002156)3.31106406
17Abnormality of homocysteine metabolism (HP:0010919)3.31106406
18Meckel diverticulum (HP:0002245)3.27188788
19Pallor (HP:0000980)3.24631847
20Aplasia/Hypoplasia of the uvula (HP:0010293)3.21153068
21Medulloblastoma (HP:0002885)3.20850544
22Abnormality of reticulocytes (HP:0004312)3.18777381
23Abnormality of the ileum (HP:0001549)3.17002155
24Absent radius (HP:0003974)3.13891855
25Macrocytic anemia (HP:0001972)3.09749695
26Abnormality of the astrocytes (HP:0100707)3.03718026
27Astrocytoma (HP:0009592)3.03718026
28Aplasia involving forearm bones (HP:0009822)2.93128433
29Absent forearm bone (HP:0003953)2.93128433
30Abnormality of cochlea (HP:0000375)2.91083240
31Abnormality of the preputium (HP:0100587)2.90471692
32Supernumerary spleens (HP:0009799)2.89202776
33Abnormality of chromosome stability (HP:0003220)2.89173763
34Ectopic kidney (HP:0000086)2.87100790
35Rhabdomyosarcoma (HP:0002859)2.82501045
36Selective tooth agenesis (HP:0001592)2.80860041
37Glioma (HP:0009733)2.78898509
38Abnormality of the anterior horn cell (HP:0006802)2.70143874
39Degeneration of anterior horn cells (HP:0002398)2.70143874
40Facial hemangioma (HP:0000329)2.67954432
41Abnormality of the aortic arch (HP:0012303)2.66449384
42Cholecystitis (HP:0001082)2.60462476
43Abnormal gallbladder physiology (HP:0012438)2.60462476
44Intestinal fistula (HP:0100819)2.59535031
45Reticulocytosis (HP:0001923)2.59259922
46Aplasia/hypoplasia of the humerus (HP:0006507)2.56338893
47Hyperthyroidism (HP:0000836)2.55642528
48Cortical dysplasia (HP:0002539)2.54494754
49Neoplasm of the oral cavity (HP:0100649)2.53915542
50Anal stenosis (HP:0002025)2.53542887
51Duodenal stenosis (HP:0100867)2.42921961
52Small intestinal stenosis (HP:0012848)2.42921961
53Neoplasm of striated muscle (HP:0009728)2.42079184
54Carpal bone hypoplasia (HP:0001498)2.41602335
55Hypoparathyroidism (HP:0000829)2.41442508
56Abnormal number of incisors (HP:0011064)2.40482761
57Aplasia/Hypoplasia of the sacrum (HP:0008517)2.38656995
58Abnormality of the carotid arteries (HP:0005344)2.36767706
59Short humerus (HP:0005792)2.36159971
60Breast aplasia (HP:0100783)2.35061303
61Prominent nose (HP:0000448)2.33905091
62Duplication of thumb phalanx (HP:0009942)2.32728796
63Nephroblastoma (Wilms tumor) (HP:0002667)2.30791425
64Bowel incontinence (HP:0002607)2.29326132
65Abnormality of the lower motor neuron (HP:0002366)2.25182875
66Aplasia/Hypoplasia of the sternum (HP:0006714)2.24299597
67Rectal fistula (HP:0100590)2.24298805
68Rectovaginal fistula (HP:0000143)2.24298805
69Morphological abnormality of the inner ear (HP:0011390)2.23165874
70Abnormal large intestine physiology (HP:0012700)2.22555328
71Aplasia/Hypoplasia of the breasts (HP:0010311)2.21621973
72Myelodysplasia (HP:0002863)2.19300055
73Tracheoesophageal fistula (HP:0002575)2.17640564
74Embryonal renal neoplasm (HP:0011794)2.16141306
75Partial agenesis of the corpus callosum (HP:0001338)2.16094230
76Abnormality of the duodenum (HP:0002246)2.14018408
77Spinal muscular atrophy (HP:0007269)2.11485803
78Sloping forehead (HP:0000340)2.10003883
79Hemivertebrae (HP:0002937)2.08303411
80Horseshoe kidney (HP:0000085)2.08256691
81Absent thumb (HP:0009777)2.06629399
82Aplasia/Hypoplasia of the earlobes (HP:0009906)2.05475756
83Triphalangeal thumb (HP:0001199)2.03905411
84Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.03577805
85Sparse lateral eyebrow (HP:0005338)2.03552125
86Short thumb (HP:0009778)2.02780571
87Oral leukoplakia (HP:0002745)2.02179209
88Missing ribs (HP:0000921)2.02178419
89Partial duplication of thumb phalanx (HP:0009944)2.01717309
90Long eyelashes (HP:0000527)2.00492263
91Increased nuchal translucency (HP:0010880)1.99818223
92High anterior hairline (HP:0009890)1.98965458
93Abnormality of DNA repair (HP:0003254)1.98347579
94Colon cancer (HP:0003003)1.97618542
95Duplicated collecting system (HP:0000081)1.97491607
96Abdominal situs inversus (HP:0003363)1.96990828
97Abnormality of abdominal situs (HP:0011620)1.96990828
98Volvulus (HP:0002580)1.96728453
99Abnormal lung lobation (HP:0002101)1.96043816
100Atresia of the external auditory canal (HP:0000413)1.95453712
101Abnormality of sulfur amino acid metabolism (HP:0004339)1.95075998
102Agnosia (HP:0010524)1.94479623
103Cafe-au-lait spot (HP:0000957)1.93830566
104Bilateral microphthalmos (HP:0007633)1.92609252
105Atrophy/Degeneration involving motor neurons (HP:0007373)1.92527587
106Esophageal atresia (HP:0002032)1.92273136
107Septate vagina (HP:0001153)1.91782805
108Deviation of the thumb (HP:0009603)1.89530515
109Cheekbone underdevelopment (HP:0010669)1.89494027
110Papillary thyroid carcinoma (HP:0002895)1.89255524
111Multiple enchondromatosis (HP:0005701)1.89185575
112Premature ovarian failure (HP:0008209)1.87859347
113Disproportionate tall stature (HP:0001519)1.87524075
114Seborrheic dermatitis (HP:0001051)1.86928136
115Proximal placement of thumb (HP:0009623)1.86876468
116Bicornuate uterus (HP:0000813)1.86703510
117Osteomalacia (HP:0002749)1.85600433
118Renal duplication (HP:0000075)1.83429883
119Hepatoblastoma (HP:0002884)1.81493409
120Midline defect of the nose (HP:0004122)1.80766092
121Septo-optic dysplasia (HP:0100842)1.80186848
122Oligodactyly (HP:0012165)1.79992143
123Bone marrow hypocellularity (HP:0005528)1.78735582
124Spina bifida occulta (HP:0003298)1.78157502
125Heterotopia (HP:0002282)1.76992400
126Short middle phalanx of the 5th finger (HP:0004220)1.76220332
127Abnormality of the renal collecting system (HP:0004742)1.75621695
128Supernumerary ribs (HP:0005815)1.75227189
129Adrenal hypoplasia (HP:0000835)1.74506309
130Partial duplication of the phalanx of hand (HP:0009999)1.74474433
131Overlapping toe (HP:0001845)1.74313817
132Sandal gap (HP:0001852)1.74058102
133Pendular nystagmus (HP:0012043)1.73539615
134Obsessive-compulsive behavior (HP:0000722)1.72696109
135Rough bone trabeculation (HP:0100670)1.71603491
136Anal atresia (HP:0002023)1.70835891
137Vaginal fistula (HP:0004320)1.70655377
138Supernumerary bones of the axial skeleton (HP:0009144)1.70089790
139Transposition of the great arteries (HP:0001669)1.69949664
140Abnormal connection of the cardiac segments (HP:0011545)1.69949664
141Abnormal ventriculo-arterial connection (HP:0011563)1.69949664
142Squamous cell carcinoma (HP:0002860)1.69884957
143Clubbing of toes (HP:0100760)1.69615639
144Ankyloglossia (HP:0010296)1.69415004
145Absent septum pellucidum (HP:0001331)1.69032309
146Malignant gastrointestinal tract tumors (HP:0006749)1.68763385
147Gastrointestinal carcinoma (HP:0002672)1.68763385
148Choanal atresia (HP:0000453)1.67332492
149Hyperglycinemia (HP:0002154)1.66237425
150Abnormally folded helix (HP:0008544)1.64322823
151Abnormality of the lacrimal duct (HP:0011481)1.61959725
152Double outlet right ventricle (HP:0001719)1.61260090
153Congenital malformation of the right heart (HP:0011723)1.61260090
154Facial cleft (HP:0002006)1.61079458
155Tetralogy of Fallot (HP:0001636)1.60186426
156Deep palmar crease (HP:0006191)1.59629583

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK124.61434861
2LATS14.48279950
3WNK43.97809006
4CDC73.93693042
5LATS23.81391165
6STK38L3.80503338
7PLK43.33740694
8TTK3.03547346
9NEK23.00392243
10WEE12.87844192
11SRPK12.65757908
12BUB12.60576916
13PBK2.52080491
14EPHA22.46390541
15NME12.40367403
16STK392.20782070
17CDK72.15740988
18CHEK22.11648356
19PLK12.01349124
20AKT31.94025028
21ACVR1B1.92805642
22TNIK1.79935564
23NEK11.74019678
24STK31.69727148
25BRD41.69259497
26KSR21.66403771
27OXSR11.60680945
28CLK11.53827199
29RPS6KB21.52656542
30PLK31.47143602
31CHEK11.46606243
32MKNK21.44932645
33ATR1.40668076
34BRSK21.39615447
35MKNK11.35130372
36AURKB1.34422237
37ZAK1.31273084
38CAMK1G1.30809816
39DYRK31.30644113
40SMG11.30102749
41EIF2AK11.25570849
42TSSK61.24690116
43CDK41.23132726
44TLK11.18505101
45NTRK31.10945148
46ATM1.09863972
47AURKA1.09101433
48STK381.07871517
49CDK21.05224723
50ALK1.00653345
51CDK80.97917984
52BMX0.94682754
53PDK20.93365021
54MTOR0.92859529
55MAP3K80.92390904
56MAP3K40.92000052
57VRK20.91572952
58STK160.88620279
59STK100.88065752
60PRKCI0.87913447
61DYRK20.86099944
62BRSK10.84427631
63VRK10.80087183
64CDK10.79661330
65CAMK1D0.78985121
66MAP3K60.78635214
67TYRO30.74619142
68RAF10.73874023
69PASK0.72729163
70MELK0.70835981
71WNK10.69399868
72ICK0.69134089
73ERBB40.68892620
74PAK40.67900938
75CDK190.67380717
76NME20.66738721
77STK40.66211588
78AKT20.66099286
79NTRK20.61220070
80PIM10.60088983
81CSNK1E0.58453638
82MAP3K20.58175657
83TAOK10.56794822
84EIF2AK20.56284951
85ABL20.55966520
86EPHB20.55532335
87MAP2K70.54063500
88FGFR10.53250523
89EEF2K0.52090360
90TAOK20.51569092
91CSNK1D0.50983457
92YES10.50400861
93BRAF0.49485597
94DMPK0.49379435
95TGFBR10.49297695
96MAPK140.47515608
97CDK90.46480464
98MAP3K90.45802240
99KSR10.45026857
100GSK3B0.44154923
101MAPK100.43798007
102RPS6KA10.42879348
103TAF10.41769682
104PNCK0.41734081
105EIF2AK30.41371121
106PAK10.41231316
107MAP3K100.41156383
108TRIB30.40960042
109CSNK2A20.38626593
110PTK60.38521769
111AKT10.38239605
112FGFR20.37700489
113CDK60.37172125
114SGK10.34273536
115CSNK2A10.34035534
116CDK11A0.33603401
117PRKDC0.31057760
118DDR20.30493175
119MAPK10.30112238
120PDGFRB0.29039655
121MARK30.28909948
122RPS6KA40.28042669
123PRKAA10.27293667
124GRK10.26779884
125TESK20.26533670
126PLK20.24064436
127CDK30.23196604
128MATK0.22435514
129PDGFRA0.21470232
130ADRBK20.18882408
131MAPK80.18770254
132CAMK40.17971146
133GRK60.16124883

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.08683411
2RNA transport_Homo sapiens_hsa030133.56069554
3Mismatch repair_Homo sapiens_hsa034303.52138966
4DNA replication_Homo sapiens_hsa030303.48896215
5Cell cycle_Homo sapiens_hsa041103.19731390
6RNA polymerase_Homo sapiens_hsa030203.18442670
7Spliceosome_Homo sapiens_hsa030403.09994007
8Homologous recombination_Homo sapiens_hsa034402.99363999
9Fanconi anemia pathway_Homo sapiens_hsa034602.96442338
10Basal transcription factors_Homo sapiens_hsa030222.60319173
11mRNA surveillance pathway_Homo sapiens_hsa030152.48317075
12Nucleotide excision repair_Homo sapiens_hsa034202.47905610
13Base excision repair_Homo sapiens_hsa034102.44569077
14One carbon pool by folate_Homo sapiens_hsa006702.41009233
15Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.17563749
16Vitamin B6 metabolism_Homo sapiens_hsa007502.16641924
17RNA degradation_Homo sapiens_hsa030182.09911485
18p53 signaling pathway_Homo sapiens_hsa041152.01173503
19Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.77963340
20Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.77787224
21Oxidative phosphorylation_Homo sapiens_hsa001901.71662062
22Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.71563899
23Steroid biosynthesis_Homo sapiens_hsa001001.70312801
24Pyrimidine metabolism_Homo sapiens_hsa002401.67784528
25Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.56879125
26Parkinsons disease_Homo sapiens_hsa050121.53267941
27Non-homologous end-joining_Homo sapiens_hsa034501.52996920
28Huntingtons disease_Homo sapiens_hsa050161.49347799
29Hippo signaling pathway_Homo sapiens_hsa043901.46175683
30Basal cell carcinoma_Homo sapiens_hsa052171.41237511
31MicroRNAs in cancer_Homo sapiens_hsa052061.32878403
32Ribosome_Homo sapiens_hsa030101.28535134
33Oocyte meiosis_Homo sapiens_hsa041141.23958011
34Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.23938009
35Proteasome_Homo sapiens_hsa030501.21387592
36Thyroid cancer_Homo sapiens_hsa052161.14922401
37Hedgehog signaling pathway_Homo sapiens_hsa043401.11844644
38Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.09688513
39Notch signaling pathway_Homo sapiens_hsa043301.09348232
40TGF-beta signaling pathway_Homo sapiens_hsa043501.01886716
41Epstein-Barr virus infection_Homo sapiens_hsa051691.01370240
42Systemic lupus erythematosus_Homo sapiens_hsa053220.99023513
43Adherens junction_Homo sapiens_hsa045200.98845670
44Purine metabolism_Homo sapiens_hsa002300.98316115
45Viral carcinogenesis_Homo sapiens_hsa052030.97553228
46Lysine degradation_Homo sapiens_hsa003100.97411350
47Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.97091223
48mTOR signaling pathway_Homo sapiens_hsa041500.96972433
49Herpes simplex infection_Homo sapiens_hsa051680.96883192
50Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.90608698
51Collecting duct acid secretion_Homo sapiens_hsa049660.90065892
52Pentose phosphate pathway_Homo sapiens_hsa000300.89742041
53Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.89133226
54Colorectal cancer_Homo sapiens_hsa052100.86078039
55Pyruvate metabolism_Homo sapiens_hsa006200.84197504
56HTLV-I infection_Homo sapiens_hsa051660.81556049
57Small cell lung cancer_Homo sapiens_hsa052220.75972046
58Maturity onset diabetes of the young_Homo sapiens_hsa049500.75477605
59Cardiac muscle contraction_Homo sapiens_hsa042600.75441292
60Transcriptional misregulation in cancer_Homo sapiens_hsa052020.74716124
612-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.73959792
62Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.73899812
63Wnt signaling pathway_Homo sapiens_hsa043100.73018505
64Endometrial cancer_Homo sapiens_hsa052130.71646324
65Bladder cancer_Homo sapiens_hsa052190.70046184
66Biosynthesis of amino acids_Homo sapiens_hsa012300.69529859
67Carbon metabolism_Homo sapiens_hsa012000.66919993
68Thyroid hormone signaling pathway_Homo sapiens_hsa049190.65361566
69Tight junction_Homo sapiens_hsa045300.64396359
70Alzheimers disease_Homo sapiens_hsa050100.63349756
71Pathways in cancer_Homo sapiens_hsa052000.61820369
72Vitamin digestion and absorption_Homo sapiens_hsa049770.61771094
73Prostate cancer_Homo sapiens_hsa052150.61457246
74Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.61030460
75Olfactory transduction_Homo sapiens_hsa047400.59347944
76Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.57996557
77Melanoma_Homo sapiens_hsa052180.56415150
78Selenocompound metabolism_Homo sapiens_hsa004500.53303618
79Chronic myeloid leukemia_Homo sapiens_hsa052200.50781187
80Renal cell carcinoma_Homo sapiens_hsa052110.50230723
81Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.49338765
82Nicotine addiction_Homo sapiens_hsa050330.49005293
83Fructose and mannose metabolism_Homo sapiens_hsa000510.48507576
84Longevity regulating pathway - mammal_Homo sapiens_hsa042110.47722371
85Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.47611791
86FoxO signaling pathway_Homo sapiens_hsa040680.47289414
87Cysteine and methionine metabolism_Homo sapiens_hsa002700.46516486
88Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.46128082
89Non-small cell lung cancer_Homo sapiens_hsa052230.44641261
90Folate biosynthesis_Homo sapiens_hsa007900.44470072
91Metabolic pathways_Homo sapiens_hsa011000.42990046
92Protein export_Homo sapiens_hsa030600.42518574
93Central carbon metabolism in cancer_Homo sapiens_hsa052300.42512005
94Alcoholism_Homo sapiens_hsa050340.41457551
95Arginine and proline metabolism_Homo sapiens_hsa003300.40039897
96Fatty acid biosynthesis_Homo sapiens_hsa000610.39541283
97Arginine biosynthesis_Homo sapiens_hsa002200.38714221
98Synaptic vesicle cycle_Homo sapiens_hsa047210.38163192
99Regulation of actin cytoskeleton_Homo sapiens_hsa048100.37559490
100Acute myeloid leukemia_Homo sapiens_hsa052210.37376659
101ErbB signaling pathway_Homo sapiens_hsa040120.36800502
102Pancreatic cancer_Homo sapiens_hsa052120.36422658
103Type II diabetes mellitus_Homo sapiens_hsa049300.35837986
104Linoleic acid metabolism_Homo sapiens_hsa005910.35478960
105Cyanoamino acid metabolism_Homo sapiens_hsa004600.35289371
106Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.34888817
107Apoptosis_Homo sapiens_hsa042100.33297585
108Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.31706012
109Insulin signaling pathway_Homo sapiens_hsa049100.30928077
110Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.30856827
111HIF-1 signaling pathway_Homo sapiens_hsa040660.30744921
112Hepatitis B_Homo sapiens_hsa051610.29999346
113Galactose metabolism_Homo sapiens_hsa000520.29988173
114Fat digestion and absorption_Homo sapiens_hsa049750.29716563
115Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.29571770
116Antigen processing and presentation_Homo sapiens_hsa046120.27744409
117Proteoglycans in cancer_Homo sapiens_hsa052050.27416365
118alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.26687274
119Choline metabolism in cancer_Homo sapiens_hsa052310.26214040
120Influenza A_Homo sapiens_hsa051640.25520829
121Arachidonic acid metabolism_Homo sapiens_hsa005900.25287359
122Regulation of autophagy_Homo sapiens_hsa041400.24938211
123Inositol phosphate metabolism_Homo sapiens_hsa005620.24210844
124Vibrio cholerae infection_Homo sapiens_hsa051100.24088410
125N-Glycan biosynthesis_Homo sapiens_hsa005100.23390176
126Melanogenesis_Homo sapiens_hsa049160.23006124
127Prolactin signaling pathway_Homo sapiens_hsa049170.21775600
128Circadian rhythm_Homo sapiens_hsa047100.21543464
129PI3K-Akt signaling pathway_Homo sapiens_hsa041510.21386206
130Viral myocarditis_Homo sapiens_hsa054160.20879355
131Sulfur relay system_Homo sapiens_hsa041220.20724926
132AMPK signaling pathway_Homo sapiens_hsa041520.20565108
133Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.19312959
134Phototransduction_Homo sapiens_hsa047440.17370180
135Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.17148859
136Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.16649843

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