HID1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.90552714
2regulation of short-term neuronal synaptic plasticity (GO:0048172)4.77752343
3Golgi transport vesicle coating (GO:0048200)4.59233442
4COPI coating of Golgi vesicle (GO:0048205)4.59233442
5synaptic vesicle maturation (GO:0016188)4.56781265
6regulation of synaptic vesicle exocytosis (GO:2000300)4.30302538
7synaptic vesicle exocytosis (GO:0016079)4.16867350
8positive regulation of synapse maturation (GO:0090129)4.00374031
9cytoskeletal anchoring at plasma membrane (GO:0007016)3.74983199
10glutamate secretion (GO:0014047)3.74722596
11regulation of synaptic vesicle transport (GO:1902803)3.73082051
12cerebellar granule cell differentiation (GO:0021707)3.61622493
13locomotory exploration behavior (GO:0035641)3.59161506
14positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.55740218
15regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022353.51203075
16synaptic vesicle docking involved in exocytosis (GO:0016081)3.50505634
17semaphorin-plexin signaling pathway (GO:0071526)3.46572933
18maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.42213204
19protein maturation by protein folding (GO:0022417)3.41164360
20neuronal action potential propagation (GO:0019227)3.36695426
21ear development (GO:0043583)3.34377453
22exocrine pancreas development (GO:0031017)3.33225249
23neuron cell-cell adhesion (GO:0007158)3.32984114
24negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)3.32267783
25regulation of synapse maturation (GO:0090128)3.27309966
26protein retention in ER lumen (GO:0006621)3.25482541
27adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.25406475
28regulation of clathrin-mediated endocytosis (GO:2000369)3.25124873
29vocalization behavior (GO:0071625)3.24977131
30neurotransmitter secretion (GO:0007269)3.22780427
31dendritic spine organization (GO:0097061)3.22675827
32retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.21440093
33regulation of female receptivity (GO:0045924)3.21171204
34intestinal epithelial cell development (GO:0060576)3.20984415
35chemosensory behavior (GO:0007635)3.13062775
36regulation of neuronal synaptic plasticity (GO:0048168)3.11398136
37insulin secretion (GO:0030073)3.07610082
38detection of calcium ion (GO:0005513)3.04105577
39regulation of calcium ion-dependent exocytosis (GO:0017158)3.03904042
40cellular potassium ion homeostasis (GO:0030007)3.03053553
41apical protein localization (GO:0045176)3.01742387
42myelin maintenance (GO:0043217)3.01255013
43cerebellar Purkinje cell layer development (GO:0021680)3.01222636
44negative regulation of cell size (GO:0045792)2.99826077
45activation of protein kinase A activity (GO:0034199)2.99339761
46cell migration in hindbrain (GO:0021535)2.97514418
47regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.95840945
48synaptic transmission, glutamatergic (GO:0035249)2.94799391
49peptidyl-tyrosine autophosphorylation (GO:0038083)2.94656761
50dopamine receptor signaling pathway (GO:0007212)2.94563963
51regulation of vesicle fusion (GO:0031338)2.94510346
52regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.94093107
53protein localization to synapse (GO:0035418)2.93713247
54glycine transport (GO:0015816)2.93486905
55layer formation in cerebral cortex (GO:0021819)2.92404069
56regulation of neurotransmitter levels (GO:0001505)2.90313451
57desmosome organization (GO:0002934)2.89080553
58regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)2.88687201
59regulation of glutamate receptor signaling pathway (GO:1900449)2.87694909
60neuromuscular process controlling posture (GO:0050884)2.85163864
61endothelial cell chemotaxis (GO:0035767)2.85064854
62cerebellar Purkinje cell differentiation (GO:0021702)2.83919860
63transmission of nerve impulse (GO:0019226)2.82485734
64positive regulation of membrane potential (GO:0045838)2.82220109
65regulation of long-term neuronal synaptic plasticity (GO:0048169)2.81242538
66ionotropic glutamate receptor signaling pathway (GO:0035235)2.80409831
67neuron-neuron synaptic transmission (GO:0007270)2.79871714
68innervation (GO:0060384)2.78262649
69positive regulation of synaptic transmission, GABAergic (GO:0032230)2.77788643
70cell-cell junction maintenance (GO:0045217)2.76525333
71long-term memory (GO:0007616)2.75870834
72exploration behavior (GO:0035640)2.75135192
73neurotransmitter transport (GO:0006836)2.73756449
74mating behavior (GO:0007617)2.73518018
75neuronal ion channel clustering (GO:0045161)2.73320102
76ER overload response (GO:0006983)2.73310623
77positive regulation of exocytosis (GO:0045921)2.73290817
78positive regulation of potassium ion transport (GO:0043268)2.71557243
79potassium ion homeostasis (GO:0055075)2.71434124
80regulation of synapse structural plasticity (GO:0051823)2.71325947
81cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.70883124
82dendritic spine morphogenesis (GO:0060997)2.69552495
83regulation of ARF protein signal transduction (GO:0032012)2.69063327
84regulation of neurotransmitter secretion (GO:0046928)2.68660467
85regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.67916193
86suckling behavior (GO:0001967)2.66972670
87insulin-like growth factor receptor signaling pathway (GO:0048009)2.66346185
88regulation of exocytosis (GO:0017157)2.65919209
89peptide hormone processing (GO:0016486)2.65677376
90dendrite morphogenesis (GO:0048813)2.65605808
91negative regulation of microtubule polymerization (GO:0031115)2.64273100
92protein targeting to Golgi (GO:0000042)2.63935570
93sodium ion export (GO:0071436)2.63475496
94synaptic vesicle endocytosis (GO:0048488)2.63422041
95regulation of amyloid precursor protein catabolic process (GO:1902991)2.63066112
96cell communication involved in cardiac conduction (GO:0086065)2.62777903
97membrane hyperpolarization (GO:0060081)2.62628734
98membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.62523793
99response to pheromone (GO:0019236)2.62192171
100vesicle coating (GO:0006901)2.61650450
101female mating behavior (GO:0060180)2.61344791
102gamma-aminobutyric acid signaling pathway (GO:0007214)2.61274077
103vesicle transport along microtubule (GO:0047496)2.61122229
104cellular response to glucagon stimulus (GO:0071377)2.59625116
105neuron recognition (GO:0008038)2.58812008
106endocrine pancreas development (GO:0031018)2.57996740
107glutamate receptor signaling pathway (GO:0007215)2.57030097
108presynaptic membrane organization (GO:0097090)2.56853685
109long-term synaptic potentiation (GO:0060291)2.55805446
110activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.54721678
111regulation of interleukin-13 production (GO:0032656)2.54413981
112presynaptic membrane assembly (GO:0097105)2.54091383
113negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.53575308
114regulation of cholesterol homeostasis (GO:2000188)2.53488542
115membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.52936824
116phosphatidylinositol 3-kinase signaling (GO:0014065)2.52638525
117regulation of neurotransmitter transport (GO:0051588)2.52523322
118cell communication by electrical coupling (GO:0010644)2.52520736
119nerve growth factor signaling pathway (GO:0038180)2.52128393
120regulation of insulin secretion (GO:0050796)2.50726735
121positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.50641294
122establishment of mitochondrion localization (GO:0051654)2.49892752
123lung epithelium development (GO:0060428)2.48749648
124regulation of synaptic plasticity (GO:0048167)2.48621814
125central nervous system myelination (GO:0022010)2.48511015
126axon ensheathment in central nervous system (GO:0032291)2.48511015
127biotin metabolic process (GO:0006768)2.47282926
128potassium ion import (GO:0010107)2.46693093
129regulation of excitatory postsynaptic membrane potential (GO:0060079)2.46432018
130auditory behavior (GO:0031223)2.45408782
131synapse assembly (GO:0007416)2.45303733
132asymmetric protein localization (GO:0008105)2.44561513
133regulation of postsynaptic membrane potential (GO:0060078)2.43623037
134glandular epithelial cell differentiation (GO:0002067)2.43593328
135membrane repolarization (GO:0086009)2.43467765
136long term synaptic depression (GO:0060292)2.42348295
137regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.40209637
138regulation of cholesterol biosynthetic process (GO:0045540)2.38223351
139amino acid import (GO:0043090)2.38206566
140phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.37311734
141signal release (GO:0023061)2.36422876
142cellular sodium ion homeostasis (GO:0006883)2.34317516
143establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.33236943
144mitochondrion transport along microtubule (GO:0047497)2.33236943
145macroautophagy (GO:0016236)2.32542166
146positive regulation of cellular amine metabolic process (GO:0033240)2.31869468
147cell junction maintenance (GO:0034331)2.31017735
148neuromuscular process controlling balance (GO:0050885)2.30630323
149cochlea development (GO:0090102)2.28365910
150activation of Rac GTPase activity (GO:0032863)2.27100583
151acid secretion (GO:0046717)2.26973519
152regulation of establishment or maintenance of cell polarity (GO:0032878)2.26393557

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.09203382
2ESR1_21235772_ChIP-Seq_MCF-7_Human3.36968047
3ESR1_20079471_ChIP-ChIP_T-47D_Human3.34204963
4TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.08820033
5THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.89697610
6GBX2_23144817_ChIP-Seq_PC3_Human2.89599438
7SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.71473265
8SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.70442170
9REST_21632747_ChIP-Seq_MESCs_Mouse2.57391397
10SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.51875037
11DROSHA_22980978_ChIP-Seq_HELA_Human2.47782045
12RACK7_27058665_Chip-Seq_MCF-7_Human2.45196100
13JARID2_20064375_ChIP-Seq_MESCs_Mouse2.42608850
14JARID2_20075857_ChIP-Seq_MESCs_Mouse2.39596929
15MTF2_20144788_ChIP-Seq_MESCs_Mouse2.39355712
16RARB_27405468_Chip-Seq_BRAIN_Mouse2.29539543
17TP63_17297297_ChIP-ChIP_HaCaT_Human2.28521325
18LXR_22292898_ChIP-Seq_THP-1_Human2.26085651
19SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.25716601
20RNF2_18974828_ChIP-Seq_MESCs_Mouse2.22582955
21EZH2_18974828_ChIP-Seq_MESCs_Mouse2.22582955
22EZH2_27294783_Chip-Seq_ESCs_Mouse2.21952371
23SUZ12_27294783_Chip-Seq_ESCs_Mouse2.21780600
24SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.17004125
25EZH2_27304074_Chip-Seq_ESCs_Mouse2.15588568
26REST_18959480_ChIP-ChIP_MESCs_Mouse2.13050013
27SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.08313582
28RUNX1_27514584_Chip-Seq_MCF-7_Human2.05591706
29ZNF263_19887448_ChIP-Seq_K562_Human2.03375681
30RNF2_27304074_Chip-Seq_ESCs_Mouse1.97389003
31FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.95619747
32ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.91224084
33EED_16625203_ChIP-ChIP_MESCs_Mouse1.83963094
34CREB1_26743006_Chip-Seq_LNCaP_Human1.80252848
35ESR1_15608294_ChIP-ChIP_MCF-7_Human1.72304765
36KDM2B_26808549_Chip-Seq_SUP-B15_Human1.65397950
37NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.62881034
38GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.62879728
39EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.61777909
40CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.60435677
41NR3C1_23031785_ChIP-Seq_PC12_Mouse1.59085039
42ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.56497360
43SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.56229765
44SMC4_20622854_ChIP-Seq_HELA_Human1.56218169
45ZNF274_21170338_ChIP-Seq_K562_Hela1.52582078
46CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.51855870
47TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.50181946
48ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.46934896
49P68_20966046_ChIP-Seq_HELA_Human1.45857678
50CTBP2_25329375_ChIP-Seq_LNCAP_Human1.42246994
51TET1_21451524_ChIP-Seq_MESCs_Mouse1.42131318
52ERG_21242973_ChIP-ChIP_JURKAT_Human1.42000620
53ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.41175913
54ZFP281_27345836_Chip-Seq_ESCs_Mouse1.40892755
55IKZF1_21737484_ChIP-ChIP_HCT116_Human1.40007262
56CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.38659013
57ZNF217_24962896_ChIP-Seq_MCF-7_Human1.37956986
58SMAD4_21799915_ChIP-Seq_A2780_Human1.34970498
59KDM2B_26808549_Chip-Seq_DND41_Human1.34063051
60TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.33970325
61SOX2_27498859_Chip-Seq_STOMACH_Mouse1.33149736
62SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.32082211
63TAF15_26573619_Chip-Seq_HEK293_Human1.30650072
64AR_21572438_ChIP-Seq_LNCaP_Human1.29192922
65CDX2_20551321_ChIP-Seq_CACO-2_Human1.27503883
66MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.25756059
67WT1_25993318_ChIP-Seq_PODOCYTE_Human1.25566543
68KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.25386495
69OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.25227856
70OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.24980523
71PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.24176995
72PIAS1_25552417_ChIP-Seq_VCAP_Human1.24070210
73RARG_19884340_ChIP-ChIP_MEFs_Mouse1.23953917
74SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.23774616
75DNAJC2_21179169_ChIP-ChIP_NT2_Human1.23534823
76STAT3_23295773_ChIP-Seq_U87_Human1.20641717
77TCF7_22412390_ChIP-Seq_EML_Mouse1.20535822
78CTBP1_25329375_ChIP-Seq_LNCAP_Human1.20181335
79SOX2_21211035_ChIP-Seq_LN229_Gbm1.18268478
80SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.17768927
81STAT6_21828071_ChIP-Seq_BEAS2B_Human1.16742906
82BMI1_23680149_ChIP-Seq_NPCS_Mouse1.16693961
83SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.16261514
84AR_19668381_ChIP-Seq_PC3_Human1.14266194
85IGF1R_20145208_ChIP-Seq_DFB_Human1.14187992
86RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.11728190
87UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.10657340
88KDM2B_26808549_Chip-Seq_K562_Human1.09662495
89SRY_22984422_ChIP-ChIP_TESTIS_Rat1.09459447
90RING1B_27294783_Chip-Seq_ESCs_Mouse1.08700287
91AHR_22903824_ChIP-Seq_MCF-7_Human1.08452144
92CDX2_19796622_ChIP-Seq_MESCs_Mouse1.07312125
93SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.06621844
94VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.06467442
95HIF1A_21447827_ChIP-Seq_MCF-7_Human1.05913796
96KLF5_25053715_ChIP-Seq_YYC3_Human1.05879418
97ELK3_25401928_ChIP-Seq_HUVEC_Human1.05398392
98PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.05299832
99ARNT_22903824_ChIP-Seq_MCF-7_Human1.05119691
100SA1_27219007_Chip-Seq_ERYTHROID_Human1.05106936
101RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.04851159
102P53_22127205_ChIP-Seq_FIBROBLAST_Human1.04431104
103CTCF_27219007_Chip-Seq_ERYTHROID_Human1.04003679
104PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.03660831
105PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.03339840
106TOP2B_26459242_ChIP-Seq_MCF-7_Human1.03011629
107SMAD3_21741376_ChIP-Seq_EPCs_Human1.02139616
108ZFP57_27257070_Chip-Seq_ESCs_Mouse1.01657077
109NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.01249130
110MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.01247598
111OCT4_19829295_ChIP-Seq_ESCs_Human1.00570894
112ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.00044835
113GATA3_24758297_ChIP-Seq_MCF-7_Human0.99451361
114YAP1_20516196_ChIP-Seq_MESCs_Mouse0.99403510
115NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.98991700
116P300_19829295_ChIP-Seq_ESCs_Human0.98587418
117TET1_21490601_ChIP-Seq_MESCs_Mouse0.98146107
118TP63_22573176_ChIP-Seq_HFKS_Human0.97997090
119TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.97029829
120TCF4_23295773_ChIP-Seq_U87_Human0.96869893
121ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.96629060
122AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.95649935
123AR_25329375_ChIP-Seq_VCAP_Human0.95521307
124SMAD3_21741376_ChIP-Seq_ESCs_Human0.95085973
125SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.94828798
126RING1B_27294783_Chip-Seq_NPCs_Mouse0.94669533
127EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.94525392
128WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.94502374
129GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.94490103
130CTCF_27219007_Chip-Seq_Bcells_Human0.94413101
131SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.93930354
132TP53_20018659_ChIP-ChIP_R1E_Mouse0.93781324
133RARB_24833708_ChIP-Seq_LIVER_Mouse0.92106551
134PKCTHETA_26484144_Chip-Seq_BREAST_Human0.91109193
135TRIM28_21343339_ChIP-Seq_HEK293_Human0.90291239
136TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89619143
137CBX2_27304074_Chip-Seq_ESCs_Mouse0.89388376
138TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.88435648
139SMAD4_21741376_ChIP-Seq_HESCs_Human0.87900015
140RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.87868758
141ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.87808986
142POU3F2_20337985_ChIP-ChIP_501MEL_Human0.87585821
143ESR2_21235772_ChIP-Seq_MCF-7_Human0.87200730
144NR3C1_21868756_ChIP-Seq_MCF10A_Human0.85441693
145LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.83991381
146RUNX2_22187159_ChIP-Seq_PCA_Human0.80911375
147MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.80715926
148CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.80470046
149ZFP281_18757296_ChIP-ChIP_E14_Mouse0.79334529
150MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.78678806
151TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.78180048

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.34337062
2MP0004270_analgesia3.75129682
3MP0003880_abnormal_central_pattern3.30346392
4MP0003635_abnormal_synaptic_transmissio3.06980301
5MP0002909_abnormal_adrenal_gland2.97693871
6MP0009780_abnormal_chondrocyte_physiolo2.87227518
7MP0010386_abnormal_urinary_bladder2.50179943
8MP0003123_paternal_imprinting2.46070252
9MP0009745_abnormal_behavioral_response2.38037367
10MP0002734_abnormal_mechanical_nocicepti2.36891711
11MP0003283_abnormal_digestive_organ2.33835870
12MP0004043_abnormal_pH_regulation2.32527860
13MP0002064_seizures2.32425443
14MP0002063_abnormal_learning/memory/cond2.28624890
15MP0002272_abnormal_nervous_system2.24407827
16MP0000013_abnormal_adipose_tissue2.23291728
17MP0005646_abnormal_pituitary_gland2.08403804
18MP0002572_abnormal_emotion/affect_behav2.03660055
19MP0001968_abnormal_touch/_nociception1.99194209
20MP0003329_amyloid_beta_deposits1.97140614
21MP0003183_abnormal_peptide_metabolism1.97008618
22MP0002822_catalepsy1.96737709
23MP0002693_abnormal_pancreas_physiology1.93231236
24MP0005423_abnormal_somatic_nervous1.93003746
25MP0002733_abnormal_thermal_nociception1.91229351
26MP0001486_abnormal_startle_reflex1.89408035
27MP0009046_muscle_twitch1.85926426
28MP0002796_impaired_skin_barrier1.82375117
29MP0001970_abnormal_pain_threshold1.81930532
30MP0001944_abnormal_pancreas_morphology1.77681101
31MP0005645_abnormal_hypothalamus_physiol1.74018607
32MP0002735_abnormal_chemical_nociception1.71594678
33MP0005409_darkened_coat_color1.71361391
34MP0003122_maternal_imprinting1.69125183
35MP0001501_abnormal_sleep_pattern1.64960115
36MP0005379_endocrine/exocrine_gland_phen1.64375647
37MP0008569_lethality_at_weaning1.63477916
38MP0002249_abnormal_larynx_morphology1.61795999
39MP0000537_abnormal_urethra_morphology1.60637825
40MP0002184_abnormal_innervation1.59511487
41MP0001502_abnormal_circadian_rhythm1.57578824
42MP0005220_abnormal_exocrine_pancreas1.57366895
43MP0000566_synostosis1.54979258
44MP0002067_abnormal_sensory_capabilities1.54633314
45MP0000955_abnormal_spinal_cord1.53910819
46MP0001664_abnormal_digestion1.50810734
47MP0002098_abnormal_vibrissa_morphology1.48513837
48MP0004858_abnormal_nervous_system1.46930480
49MP0004782_abnormal_surfactant_physiolog1.46360463
50MP0002877_abnormal_melanocyte_morpholog1.44829437
51MP0006072_abnormal_retinal_apoptosis1.43157055
52MP0004811_abnormal_neuron_physiology1.42780946
53MP0002557_abnormal_social/conspecific_i1.40898531
54MP0001440_abnormal_grooming_behavior1.40494327
55MP0006276_abnormal_autonomic_nervous1.40248255
56MP0000778_abnormal_nervous_system1.39790356
57MP0002736_abnormal_nociception_after1.38636614
58MP0003705_abnormal_hypodermis_morpholog1.36728974
59MP0005386_behavior/neurological_phenoty1.35494545
60MP0004924_abnormal_behavior1.35494545
61MP0000678_abnormal_parathyroid_gland1.32967326
62MP0004885_abnormal_endolymph1.30392003
63MP0000920_abnormal_myelination1.29181419
64MP0002882_abnormal_neuron_morphology1.27940617
65MP0008961_abnormal_basal_metabolism1.24408109
66MP0003787_abnormal_imprinting1.24139098
67MP0002229_neurodegeneration1.23043448
68MP0003868_abnormal_feces_composition1.21719093
69MP0000462_abnormal_digestive_system1.20336140
70MP0003879_abnormal_hair_cell1.20127868
71MP0000003_abnormal_adipose_tissue1.19329549
72MP0001984_abnormal_olfaction1.19243312
73MP0003633_abnormal_nervous_system1.18996199
74MP0002066_abnormal_motor_capabilities/c1.18451182
75MP0002234_abnormal_pharynx_morphology1.15464806
76MP0001765_abnormal_ion_homeostasis1.14794943
77MP0001666_abnormal_nutrient_absorption1.14676450
78MP0001529_abnormal_vocalization1.13759665
79MP0004145_abnormal_muscle_electrophysio1.12905359
80MP0000631_abnormal_neuroendocrine_gland1.12324243
81MP0001905_abnormal_dopamine_level1.11939403
82MP0002837_dystrophic_cardiac_calcinosis1.10924660
83MP0001873_stomach_inflammation1.09213814
84MP0010678_abnormal_skin_adnexa1.08702158
85MP0003634_abnormal_glial_cell1.07949661
86MP0000579_abnormal_nail_morphology1.07593260
87MP0008872_abnormal_physiological_respon1.05503017
88MP0005551_abnormal_eye_electrophysiolog1.03814907
89MP0002078_abnormal_glucose_homeostasis1.03487040
90MP0001849_ear_inflammation1.02889873
91MP0001346_abnormal_lacrimal_gland1.00876983
92MP0005535_abnormal_body_temperature1.00106798
93MP0001348_abnormal_lacrimal_gland0.99582425
94MP0002069_abnormal_eating/drinking_beha0.98192839
95MP0004742_abnormal_vestibular_system0.98173060
96MP0002638_abnormal_pupillary_reflex0.97979996
97MP0000538_abnormal_urinary_bladder0.95773642
98MP0001188_hyperpigmentation0.95750762
99MP0003631_nervous_system_phenotype0.94029513
100MP0005083_abnormal_biliary_tract0.94019375
101MP0001986_abnormal_taste_sensitivity0.91896290
102MP0003938_abnormal_ear_development0.91404411
103MP0010234_abnormal_vibrissa_follicle0.91185689
104MP0005501_abnormal_skin_physiology0.90746675
105MP0005310_abnormal_salivary_gland0.89652334
106MP0001299_abnormal_eye_distance/0.89481007
107MP0000383_abnormal_hair_follicle0.88508925
108MP0003172_abnormal_lysosome_physiology0.88458229
109MP0003045_fibrosis0.86668043
110MP0000627_abnormal_mammary_gland0.85100977
111MP0003953_abnormal_hormone_level0.84207354
112MP0005076_abnormal_cell_differentiation0.83932247
113MP0001485_abnormal_pinna_reflex0.83768885
114MP0002089_abnormal_postnatal_growth/wei0.82933109
115MP0003195_calcinosis0.82644273
116MP0005248_abnormal_Harderian_gland0.82119715
117MP0002152_abnormal_brain_morphology0.81775829
118MP0000534_abnormal_ureter_morphology0.80186369
119MP0008874_decreased_physiological_sensi0.78221671
120MP0005394_taste/olfaction_phenotype0.77480912
121MP0005499_abnormal_olfactory_system0.77480912
122MP0005670_abnormal_white_adipose0.76284421
123MP0000681_abnormal_thyroid_gland0.75894336
124MP0002090_abnormal_vision0.75751216
125MP0000467_abnormal_esophagus_morphology0.75027267
126MP0004142_abnormal_muscle_tone0.74549615
127MP0001270_distended_abdomen0.74225553
128MP0004264_abnormal_extraembryonic_tissu0.74113069
129MP0002876_abnormal_thyroid_physiology0.73930027
130MP0004085_abnormal_heartbeat0.73875636
131MP0005058_abnormal_lysosome_morphology0.73156851
132MP0002653_abnormal_ependyma_morphology0.71851604
133MP0005365_abnormal_bile_salt0.70516510
134MP0001727_abnormal_embryo_implantation0.68221227
135MP0000427_abnormal_hair_cycle0.68116807
136MP0009672_abnormal_birth_weight0.67159302
137MP0000377_abnormal_hair_follicle0.66825338
138MP0003690_abnormal_glial_cell0.66100197
139MP0005375_adipose_tissue_phenotype0.65353511

Predicted human phenotypes

RankGene SetZ-score
1Elevated circulating parathyroid hormone (PTH) level (HP:0003165)5.14768677
2Visual hallucinations (HP:0002367)4.35005323
3Focal motor seizures (HP:0011153)4.17954865
4Myokymia (HP:0002411)4.15350906
5Obstructive sleep apnea (HP:0002870)4.09430117
6J-shaped sella turcica (HP:0002680)3.67507253
7Hyperinsulinemic hypoglycemia (HP:0000825)3.58396155
8Supranuclear gaze palsy (HP:0000605)3.52077852
9Atonic seizures (HP:0010819)3.47655936
10Focal seizures (HP:0007359)3.47543120
11Abnormality of calcium-phosphate metabolism (HP:0100530)3.43536498
12Epileptic encephalopathy (HP:0200134)3.33228968
13Decreased circulating renin level (HP:0003351)3.32322152
14Agitation (HP:0000713)3.28726574
15Hypoglycemic seizures (HP:0002173)3.19871350
16Ankle clonus (HP:0011448)3.18740400
17Symptomatic seizures (HP:0011145)3.16885833
18Germ cell neoplasia (HP:0100728)3.09277764
19Absence seizures (HP:0002121)3.02129432
20Neurofibrillary tangles (HP:0002185)2.99309737
21Lymphangioma (HP:0100764)2.98053991
22Action tremor (HP:0002345)2.94443778
23Pheochromocytoma (HP:0002666)2.93277745
24Bronchomalacia (HP:0002780)2.86796096
25EEG with generalized epileptiform discharges (HP:0011198)2.84351081
26Epileptiform EEG discharges (HP:0011182)2.82955556
27Sparse lateral eyebrow (HP:0005338)2.80055946
28Dialeptic seizures (HP:0011146)2.76871264
29Depression (HP:0000716)2.68440928
30Hypsarrhythmia (HP:0002521)2.67733620
31Anxiety (HP:0000739)2.65499138
32Cerebral inclusion bodies (HP:0100314)2.64074294
33Thin bony cortex (HP:0002753)2.63914360
34Progressive cerebellar ataxia (HP:0002073)2.63771255
35Right ventricular cardiomyopathy (HP:0011663)2.62881858
36Febrile seizures (HP:0002373)2.60684580
37Large for gestational age (HP:0001520)2.60399683
38Septate vagina (HP:0001153)2.59701594
39Spastic gait (HP:0002064)2.58964070
40Concave nail (HP:0001598)2.57768165
41Hyperactive renin-angiotensin system (HP:0000841)2.56095269
42Hyperparathyroidism (HP:0000843)2.55234184
43Type II lissencephaly (HP:0007260)2.53505772
44Generalized tonic-clonic seizures (HP:0002069)2.52542771
45Hyperacusis (HP:0010780)2.51400320
46Broad face (HP:0000283)2.50277412
47Flat acetabular roof (HP:0003180)2.49174091
48Growth hormone excess (HP:0000845)2.49072106
49Abnormality of the pancreatic islet cells (HP:0006476)2.47196199
50Abnormality of endocrine pancreas physiology (HP:0012093)2.47196199
51Abnormality of renin-angiotensin system (HP:0000847)2.46397915
52Papilledema (HP:0001085)2.45891368
53Hypothermia (HP:0002045)2.45653002
54Retinal dysplasia (HP:0007973)2.45390271
55Distal upper limb amyotrophy (HP:0007149)2.43689576
56Upper limb amyotrophy (HP:0009129)2.43689576
57Neuroendocrine neoplasm (HP:0100634)2.42830451
58Increased circulating renin level (HP:0000848)2.42758279
59Truncal ataxia (HP:0002078)2.41918585
60Testicular neoplasm (HP:0010788)2.39594984
61Bundle branch block (HP:0011710)2.39319977
62Stridor (HP:0010307)2.37451018
63Dysmetria (HP:0001310)2.35495284
64Amelogenesis imperfecta (HP:0000705)2.32873067
65Insulin-resistant diabetes mellitus (HP:0000831)2.30210691
66Failure to thrive in infancy (HP:0001531)2.26994784
67Hypokalemia (HP:0002900)2.25374401
68Sleep apnea (HP:0010535)2.25071578
69Enlarged penis (HP:0000040)2.23943737
70Hand muscle atrophy (HP:0009130)2.23846684
71Insidious onset (HP:0003587)2.20455976
72Termporal pattern (HP:0011008)2.20455976
73Visceral angiomatosis (HP:0100761)2.17989305
74Hypokalemic alkalosis (HP:0001949)2.17985662
75Ependymoma (HP:0002888)2.16157316
76Megalencephaly (HP:0001355)2.14789927
77Ventricular fibrillation (HP:0001663)2.14612713
78Ketoacidosis (HP:0001993)2.12244697
79Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.12222205
80Degeneration of the lateral corticospinal tracts (HP:0002314)2.12222205
81Menstrual irregularities (HP:0000858)2.11591163
82Limb dystonia (HP:0002451)2.11430021
83Hyperaldosteronism (HP:0000859)2.10733956
84Abnormality of the corticospinal tract (HP:0002492)2.10347183
85Neuronal loss in central nervous system (HP:0002529)2.09279114
86Testicular atrophy (HP:0000029)2.07134675
87Postural tremor (HP:0002174)2.06676258
88Adrenal overactivity (HP:0002717)2.06594425
89Amblyopia (HP:0000646)2.06429751
90Syncope (HP:0001279)2.05062720
91Dysostosis multiplex (HP:0000943)2.04896588
92Curly hair (HP:0002212)2.04403918
93Hyperkalemia (HP:0002153)2.03385340
94Deformed sella turcica (HP:0002681)2.03214895
95Pancreatic islet-cell hyperplasia (HP:0004510)2.02562679
96Hypercortisolism (HP:0001578)2.02454895
97Scanning speech (HP:0002168)2.01414330
98Congenital glaucoma (HP:0001087)1.99600010
99Abnormal pancreas size (HP:0012094)1.99535126
100Intention tremor (HP:0002080)1.99320568
101Hyperphosphatemia (HP:0002905)1.99251855
102Cerebral aneurysm (HP:0004944)1.99195254
103Prolonged QT interval (HP:0001657)1.98256183
104Pili torti (HP:0003777)1.98231334
105Spinal cord compression (HP:0002176)1.97453468
106Central scotoma (HP:0000603)1.97451516
107Macroorchidism (HP:0000053)1.97373279
108Poor eye contact (HP:0000817)1.97104173
109Abnormal eating behavior (HP:0100738)1.96258188
110Buphthalmos (HP:0000557)1.96124884
111Cortical visual impairment (HP:0100704)1.94809246
112Precocious puberty (HP:0000826)1.94398345
113Postural instability (HP:0002172)1.94146687
114Urinary urgency (HP:0000012)1.94085659
115Hypotension (HP:0002615)1.93403042
116Abnormality of potassium homeostasis (HP:0011042)1.92401443
117Neoplasm of the heart (HP:0100544)1.91570760
118Clonus (HP:0002169)1.91528303
119Torticollis (HP:0000473)1.90369627
120Diminished movement (HP:0002374)1.90101585
121Status epilepticus (HP:0002133)1.89641452
122Hemiparesis (HP:0001269)1.89215296
123Asymmetry of the thorax (HP:0001555)1.88085593
124Akinesia (HP:0002304)1.87222182
125Hydroxyprolinuria (HP:0003080)1.86699369
126Abnormality of proline metabolism (HP:0010907)1.86699369
127Impaired social interactions (HP:0000735)1.86508517
128Abnormal social behavior (HP:0012433)1.86508517
129Hemangiomatosis (HP:0007461)1.86388542
130Retinal atrophy (HP:0001105)1.86330375
131Excessive salivation (HP:0003781)1.86105920
132Drooling (HP:0002307)1.86105920
133Gaze-evoked nystagmus (HP:0000640)1.85641929
134Spinal canal stenosis (HP:0003416)1.85442461
135Hyperthyroidism (HP:0000836)1.85258098
136Peripheral hypomyelination (HP:0007182)1.84371961
137Muscular hypotonia of the trunk (HP:0008936)1.84136121
138Psychosis (HP:0000709)1.83686128
139Restlessness (HP:0000711)1.81423033
140Impaired smooth pursuit (HP:0007772)1.80666153
141Mucopolysacchariduria (HP:0008155)1.80226394
142Urinary glycosaminoglycan excretion (HP:0003541)1.80226394
143Urinary bladder sphincter dysfunction (HP:0002839)1.78798066
144Impaired vibration sensation in the lower limbs (HP:0002166)1.78690866
145Hyperglycemia (HP:0003074)1.78264206
146Lower limb asymmetry (HP:0100559)1.78244871
147Abnormality of glutamine family amino acid metabolism (HP:0010902)1.76132257
148Heterochromia iridis (HP:0001100)1.75833917
149Rapidly progressive (HP:0003678)1.74392023
150Flattened epiphyses (HP:0003071)1.73167343
151Hyperventilation (HP:0002883)1.73134085
152Broad metatarsal (HP:0001783)1.70559995
153Genetic anticipation (HP:0003743)1.70205437
154Astrocytoma (HP:0009592)1.69970209
155Abnormality of the astrocytes (HP:0100707)1.69970209
156Lower limb amyotrophy (HP:0007210)1.68547708
157Open mouth (HP:0000194)1.68445553
158Lip pit (HP:0100267)1.66252475
159Abdominal distention (HP:0003270)1.66024421
160Heart block (HP:0012722)1.65467991
161Dysmetric saccades (HP:0000641)1.65447010
162Abnormality of the aortic arch (HP:0012303)1.65032255
163Apathy (HP:0000741)1.64668743

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.93874221
2NTRK33.77916709
3SIK13.55995063
4EPHA23.41416911
5INSRR3.03969871
6PKN23.02750589
7NTRK12.71062963
8MAP3K92.67005181
9TESK12.55816979
10PRKD32.41182937
11MAP3K22.40031272
12MAP3K42.23039151
13MARK12.10924683
14KSR22.04397526
15UHMK12.04249082
16EPHA42.01364839
17PAK61.95578254
18STK391.89660477
19WNK41.88012729
20MAPK151.86905885
21FGFR41.77565308
22HIPK21.71976168
23MINK11.70274986
24DAPK21.63699075
25ICK1.61087213
26MST1R1.60679045
27CDK191.52175344
28TNK21.48723018
29TNIK1.45264688
30CAMKK21.44933390
31MAP3K11.44654393
32OXSR11.44591984
33CDK51.44435012
34MAPKAPK31.41693366
35PASK1.39853368
36MAP2K71.38080218
37EEF2K1.37018016
38TAOK31.35693909
39PRKCH1.32435295
40CAMKK11.26563668
41PRKCI1.25760554
42RPS6KA21.24656335
43SGK2231.23835187
44SGK4941.23835187
45PAK31.23401335
46PNCK1.22021189
47MUSK1.21985120
48NTRK21.21295472
49RET1.17715091
50LMTK21.11067464
51SCYL21.08357238
52MARK21.07238444
53WNK11.06559991
54ARAF1.06438013
55ERBB21.02910256
56CAMK1D1.02791086
57CAMK2B1.01360562
58FER1.01097455
59CASK1.00981526
60GRK51.00624738
61SMG11.00130120
62ERN10.98834354
63SIK20.98142510
64CSNK1G20.97814859
65SIK30.96854632
66NEK60.96695307
67PTK60.96344464
68KSR10.94030166
69MAP2K40.91735788
70FRK0.91593050
71MAPK130.90035808
72CAMK1G0.89994753
73CAMK2D0.89638676
74CDC42BPA0.89253970
75PRKD20.86910106
76PRPF4B0.86400359
77MAP3K130.85866438
78CAMK2A0.84732059
79WNK30.82084215
80CAMK10.80705859
81TAOK10.78992785
82PTK20.78808877
83PIK3CA0.78663200
84PRKCE0.78479368
85FGFR20.76352397
86PHKG20.75546950
87PHKG10.75546950
88MAP2K60.75128220
89TYRO30.74968611
90PRKCG0.73501624
91BCR0.72339019
92FES0.71731008
93CDK140.68945012
94DYRK1A0.68317831
95RPS6KB20.68058443
96MAP3K60.68005008
97STK380.67255004
98IRAK20.67119794
99MTOR0.67024119
100MAP2K10.66221012
101EPHB10.65957125
102SGK30.65817471
103RIPK10.64754376
104CSNK1G30.64142759
105MET0.64011069
106LATS20.63945785
107EPHA30.62786071
108LIMK10.62164012
109MAP3K120.61655534
110PRKG20.61275438
111MAP2K20.60203738
112PRKCZ0.60081900
113CDK150.58902868
114CDK180.58149705
115STK110.58073057
116PDPK10.58008512
117CDK120.56989445
118AKT30.56936513
119PDGFRB0.55344631
120PDGFRA0.55333908
121DAPK10.54334487
122CSNK1A1L0.54253341
123MAP3K70.54118025
124MAPKAPK50.53887909
125CAMK2G0.53254287
126PINK10.52936437
127TIE10.51374157
128CDK11A0.51130030
129BMPR20.50428103
130NME10.50076513
131SGK20.49864920
132PRKAA10.49534015
133ALK0.48196011
134PRKD10.47886403
135FYN0.47614220
136MAPK80.47517534
137MATK0.46871912
138ILK0.45928269
139DMPK0.45083946
140CHUK0.44751378
141MAPK100.44396580

Predicted pathways (KEGG)

RankGene SetZ-score
1Maturity onset diabetes of the young_Homo sapiens_hsa049503.37084289
2Insulin secretion_Homo sapiens_hsa049112.83010336
3Synaptic vesicle cycle_Homo sapiens_hsa047212.77620553
4Pancreatic secretion_Homo sapiens_hsa049722.29416548
5Protein export_Homo sapiens_hsa030602.25493899
6GABAergic synapse_Homo sapiens_hsa047272.24181482
7Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.18886570
8Nicotine addiction_Homo sapiens_hsa050332.16108039
9Circadian entrainment_Homo sapiens_hsa047132.15167595
10Cyanoamino acid metabolism_Homo sapiens_hsa004602.10703193
11Amphetamine addiction_Homo sapiens_hsa050312.06370926
12Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.03214093
13Cocaine addiction_Homo sapiens_hsa050301.96945192
14Long-term potentiation_Homo sapiens_hsa047201.93885467
15Morphine addiction_Homo sapiens_hsa050321.92721273
16Glutamatergic synapse_Homo sapiens_hsa047241.90124939
17Vibrio cholerae infection_Homo sapiens_hsa051101.89761884
18Dopaminergic synapse_Homo sapiens_hsa047281.88989479
19Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.83962881
20Taste transduction_Homo sapiens_hsa047421.81485708
21Cholinergic synapse_Homo sapiens_hsa047251.74077273
22Olfactory transduction_Homo sapiens_hsa047401.70012494
23Salivary secretion_Homo sapiens_hsa049701.67458035
24Aldosterone synthesis and secretion_Homo sapiens_hsa049251.66239604
25Type II diabetes mellitus_Homo sapiens_hsa049301.63482621
26Gastric acid secretion_Homo sapiens_hsa049711.63467021
27Serotonergic synapse_Homo sapiens_hsa047261.56116015
28Collecting duct acid secretion_Homo sapiens_hsa049661.53180456
29Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.48446572
30Renin secretion_Homo sapiens_hsa049241.43843950
31Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.41468864
32Histidine metabolism_Homo sapiens_hsa003401.40504857
33Sulfur metabolism_Homo sapiens_hsa009201.33240083
34Long-term depression_Homo sapiens_hsa047301.28070549
35Fatty acid biosynthesis_Homo sapiens_hsa000611.25918853
36Bile secretion_Homo sapiens_hsa049761.25642904
37Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.24553830
38Phenylalanine metabolism_Homo sapiens_hsa003601.20305509
39AMPK signaling pathway_Homo sapiens_hsa041521.18071440
40Phosphatidylinositol signaling system_Homo sapiens_hsa040701.14751122
41Tight junction_Homo sapiens_hsa045301.14516023
42Carbohydrate digestion and absorption_Homo sapiens_hsa049731.13914174
43Arginine and proline metabolism_Homo sapiens_hsa003301.10808806
44Notch signaling pathway_Homo sapiens_hsa043301.10626838
45Oxytocin signaling pathway_Homo sapiens_hsa049211.08755067
46ABC transporters_Homo sapiens_hsa020101.08092162
47Thyroid hormone synthesis_Homo sapiens_hsa049181.07653571
48Estrogen signaling pathway_Homo sapiens_hsa049151.07326993
49Gap junction_Homo sapiens_hsa045401.05726441
50GnRH signaling pathway_Homo sapiens_hsa049121.05176054
51Fructose and mannose metabolism_Homo sapiens_hsa000511.04643579
52Calcium signaling pathway_Homo sapiens_hsa040201.04603499
532-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.02577696
54SNARE interactions in vesicular transport_Homo sapiens_hsa041301.02273724
55Type I diabetes mellitus_Homo sapiens_hsa049401.01014647
56cAMP signaling pathway_Homo sapiens_hsa040240.98734713
57Vascular smooth muscle contraction_Homo sapiens_hsa042700.97632300
58Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.94549560
59Arginine biosynthesis_Homo sapiens_hsa002200.93041730
60Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.91372715
61cGMP-PKG signaling pathway_Homo sapiens_hsa040220.90126941
62N-Glycan biosynthesis_Homo sapiens_hsa005100.86376303
63Axon guidance_Homo sapiens_hsa043600.84269311
64Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.81879093
65Dorso-ventral axis formation_Homo sapiens_hsa043200.81030816
66Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.80359852
67ErbB signaling pathway_Homo sapiens_hsa040120.79051223
68Melanogenesis_Homo sapiens_hsa049160.78433193
69Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.76575441
70Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.75562100
71Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.74356962
72Circadian rhythm_Homo sapiens_hsa047100.73608908
73Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.73562902
74Protein digestion and absorption_Homo sapiens_hsa049740.73046208
75Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.69868366
76Lysosome_Homo sapiens_hsa041420.69322460
77beta-Alanine metabolism_Homo sapiens_hsa004100.68836865
78Vitamin digestion and absorption_Homo sapiens_hsa049770.68236060
79Inositol phosphate metabolism_Homo sapiens_hsa005620.67105848
80Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.67073903
81Phospholipase D signaling pathway_Homo sapiens_hsa040720.65469701
82Insulin resistance_Homo sapiens_hsa049310.65142470
83Regulation of autophagy_Homo sapiens_hsa041400.64743182
84Endocytosis_Homo sapiens_hsa041440.64046157
85Vitamin B6 metabolism_Homo sapiens_hsa007500.62296466
86Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.62077472
87Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.61924663
88Glioma_Homo sapiens_hsa052140.60911694
89Glycerophospholipid metabolism_Homo sapiens_hsa005640.59315255
90Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.58010141
91Central carbon metabolism in cancer_Homo sapiens_hsa052300.56153250
92Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.55960627
93Glucagon signaling pathway_Homo sapiens_hsa049220.55776573
94Glycosaminoglycan degradation_Homo sapiens_hsa005310.54610110
95Choline metabolism in cancer_Homo sapiens_hsa052310.54081105
96Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.53812225
97Renal cell carcinoma_Homo sapiens_hsa052110.53507116
98Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.52655622
99Thyroid cancer_Homo sapiens_hsa052160.52309895
100Ras signaling pathway_Homo sapiens_hsa040140.52263926
101Prolactin signaling pathway_Homo sapiens_hsa049170.51902497
102Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.51611741
103Rap1 signaling pathway_Homo sapiens_hsa040150.50159324
104Prion diseases_Homo sapiens_hsa050200.49709142
105Cardiac muscle contraction_Homo sapiens_hsa042600.49690585
106Neurotrophin signaling pathway_Homo sapiens_hsa047220.48460423
107alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.48137627
108Alcoholism_Homo sapiens_hsa050340.48036646
109Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.46826522
110MAPK signaling pathway_Homo sapiens_hsa040100.45573800
111Fatty acid metabolism_Homo sapiens_hsa012120.45294725
112Sphingolipid signaling pathway_Homo sapiens_hsa040710.44239593
113Alzheimers disease_Homo sapiens_hsa050100.43824344
114Phototransduction_Homo sapiens_hsa047440.43813219
115Hippo signaling pathway_Homo sapiens_hsa043900.42672865
116VEGF signaling pathway_Homo sapiens_hsa043700.42627642
117mTOR signaling pathway_Homo sapiens_hsa041500.41829127
118Fat digestion and absorption_Homo sapiens_hsa049750.41480100
119Ether lipid metabolism_Homo sapiens_hsa005650.41259637
120Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.40887657
121Dilated cardiomyopathy_Homo sapiens_hsa054140.40823681
122Sphingolipid metabolism_Homo sapiens_hsa006000.39006074
123Endometrial cancer_Homo sapiens_hsa052130.38578735
124Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.37342096
125Longevity regulating pathway - mammal_Homo sapiens_hsa042110.36788863
126Ovarian steroidogenesis_Homo sapiens_hsa049130.36282924
127Mineral absorption_Homo sapiens_hsa049780.35752829
128Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.34949133
129Insulin signaling pathway_Homo sapiens_hsa049100.34190820
130Thyroid hormone signaling pathway_Homo sapiens_hsa049190.33922382

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