

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of activation of Janus kinase activity (GO:0010533) | 9.13463498 |
| 2 | growth hormone receptor signaling pathway (GO:0060396) | 6.69867150 |
| 3 | maturation of SSU-rRNA (GO:0030490) | 6.64485542 |
| 4 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.99658051 |
| 5 | ATP synthesis coupled proton transport (GO:0015986) | 5.99658051 |
| 6 | chaperone-mediated protein transport (GO:0072321) | 5.98856903 |
| 7 | cellular response to growth hormone stimulus (GO:0071378) | 5.94358542 |
| 8 | viral transcription (GO:0019083) | 5.40374513 |
| 9 | ribosomal small subunit assembly (GO:0000028) | 5.19066474 |
| 10 | positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568) | 5.11993573 |
| 11 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.10098374 |
| 12 | hypothalamus development (GO:0021854) | 5.09217481 |
| 13 | translational termination (GO:0006415) | 5.03729964 |
| 14 | cell proliferation in forebrain (GO:0021846) | 4.79374526 |
| 15 | embryonic retina morphogenesis in camera-type eye (GO:0060059) | 4.66437666 |
| 16 | regulation of odontogenesis of dentin-containing tooth (GO:0042487) | 4.46766566 |
| 17 | sequestering of actin monomers (GO:0042989) | 4.41417201 |
| 18 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 4.39521341 |
| 19 | regulation of catecholamine uptake involved in synaptic transmission (GO:0051940) | 4.36914219 |
| 20 | regulation of dopamine uptake involved in synaptic transmission (GO:0051584) | 4.36914219 |
| 21 | translational elongation (GO:0006414) | 4.36224126 |
| 22 | positive regulation of T cell apoptotic process (GO:0070234) | 4.25731761 |
| 23 | T-helper 1 type immune response (GO:0042088) | 4.25413005 |
| 24 | dendritic spine morphogenesis (GO:0060997) | 4.24435048 |
| 25 | endoderm formation (GO:0001706) | 4.16627640 |
| 26 | cotranslational protein targeting to membrane (GO:0006613) | 4.12993679 |
| 27 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.12531032 |
| 28 | viral life cycle (GO:0019058) | 4.12456962 |
| 29 | protein targeting to ER (GO:0045047) | 4.09688487 |
| 30 | regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902108) | 4.04506520 |
| 31 | L-serine metabolic process (GO:0006563) | 3.95089114 |
| 32 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.92170744 |
| 33 | protein neddylation (GO:0045116) | 3.89003567 |
| 34 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.84814913 |
| 35 | cellular protein complex disassembly (GO:0043624) | 3.79527796 |
| 36 | protein localization to endoplasmic reticulum (GO:0070972) | 3.75060293 |
| 37 | DNA deamination (GO:0045006) | 3.71446500 |
| 38 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.69139286 |
| 39 | ribosomal small subunit biogenesis (GO:0042274) | 3.63037980 |
| 40 | kinetochore assembly (GO:0051382) | 3.61103257 |
| 41 | positive regulation of respiratory burst (GO:0060267) | 3.60513888 |
| 42 | head development (GO:0060322) | 3.59563146 |
| 43 | somite development (GO:0061053) | 3.59533619 |
| 44 | GTP biosynthetic process (GO:0006183) | 3.57530385 |
| 45 | cerebral cortex neuron differentiation (GO:0021895) | 3.57066174 |
| 46 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.54503042 |
| 47 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.49716352 |
| 48 | thalamus development (GO:0021794) | 3.47907891 |
| 49 | kinetochore organization (GO:0051383) | 3.47858921 |
| 50 | respiratory electron transport chain (GO:0022904) | 3.46506344 |
| 51 | electron transport chain (GO:0022900) | 3.42524586 |
| 52 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.41312451 |
| 53 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.35220385 |
| 54 | behavioral response to nicotine (GO:0035095) | 3.34677954 |
| 55 | regulation of insulin-like growth factor receptor signaling pathway (GO:0043567) | 3.32112941 |
| 56 | ATP biosynthetic process (GO:0006754) | 3.28175122 |
| 57 | positive regulation of lymphocyte apoptotic process (GO:0070230) | 3.26327710 |
| 58 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.26041242 |
| 59 | regulation of neurotransmitter uptake (GO:0051580) | 3.24914856 |
| 60 | protein complex disassembly (GO:0043241) | 3.24182801 |
| 61 | regulation of posttranscriptional gene silencing (GO:0060147) | 3.21602963 |
| 62 | regulation of gene silencing by miRNA (GO:0060964) | 3.21602963 |
| 63 | regulation of gene silencing by RNA (GO:0060966) | 3.21602963 |
| 64 | auditory behavior (GO:0031223) | 3.19246167 |
| 65 | dentate gyrus development (GO:0021542) | 3.13724279 |
| 66 | positive regulation of receptor internalization (GO:0002092) | 3.13334617 |
| 67 | pattern specification involved in kidney development (GO:0061004) | 3.12939588 |
| 68 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.07202315 |
| 69 | transmission of nerve impulse (GO:0019226) | 3.04758947 |
| 70 | mechanosensory behavior (GO:0007638) | 3.02698804 |
| 71 | response to growth hormone (GO:0060416) | 3.02465050 |
| 72 | macromolecular complex disassembly (GO:0032984) | 3.01246751 |
| 73 | telencephalon development (GO:0021537) | 3.00339856 |
| 74 | neuronal stem cell maintenance (GO:0097150) | 2.98511407 |
| 75 | UTP biosynthetic process (GO:0006228) | 2.98176317 |
| 76 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 2.97282868 |
| 77 | translational initiation (GO:0006413) | 2.96653585 |
| 78 | response to xenobiotic stimulus (GO:0009410) | 2.93622922 |
| 79 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.89952223 |
| 80 | regulation of somitogenesis (GO:0014807) | 2.89423738 |
| 81 | hydrogen ion transmembrane transport (GO:1902600) | 2.88229819 |
| 82 | anatomical structure maturation (GO:0071695) | 2.86251393 |
| 83 | protein targeting to membrane (GO:0006612) | 2.85291606 |
| 84 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.78947549 |
| 85 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.77917169 |
| 86 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.77390469 |
| 87 | cornea development in camera-type eye (GO:0061303) | 2.75606521 |
| 88 | urate metabolic process (GO:0046415) | 2.72341423 |
| 89 | protein deneddylation (GO:0000338) | 2.70573291 |
| 90 | UTP metabolic process (GO:0046051) | 2.70268157 |
| 91 | killing of cells in other organism involved in symbiotic interaction (GO:0051883) | 2.68701924 |
| 92 | disruption of cells of other organism involved in symbiotic interaction (GO:0051818) | 2.68701924 |
| 93 | response to host immune response (GO:0052572) | 2.67292861 |
| 94 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 2.67292861 |
| 95 | positive regulation by symbiont of host defense response (GO:0052509) | 2.67078681 |
| 96 | modulation by symbiont of host defense response (GO:0052031) | 2.67078681 |
| 97 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 2.67078681 |
| 98 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 2.67078681 |
| 99 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 2.67078681 |
| 100 | modulation by symbiont of host immune response (GO:0052553) | 2.67078681 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 6.70014015 |
| 2 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 6.10133799 |
| 3 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 4.44485178 |
| 4 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.68650849 |
| 5 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 2.59333947 |
| 6 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.49413322 |
| 7 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.47396336 |
| 8 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 2.44579346 |
| 9 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 2.33852762 |
| 10 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 2.28270671 |
| 11 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.22465392 |
| 12 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.20612694 |
| 13 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.20382679 |
| 14 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 2.13222342 |
| 15 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 2.09286311 |
| 16 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.01292843 |
| 17 | MYC_18940864_ChIP-ChIP_HL60_Human | 2.00652763 |
| 18 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.99720777 |
| 19 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.93217859 |
| 20 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.91187321 |
| 21 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.85767563 |
| 22 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.75426605 |
| 23 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.75071324 |
| 24 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.74771836 |
| 25 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.71172978 |
| 26 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.62942544 |
| 27 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.61647562 |
| 28 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.61614617 |
| 29 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.58199307 |
| 30 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.58199307 |
| 31 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.57578261 |
| 32 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.56847834 |
| 33 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.56544606 |
| 34 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.56363272 |
| 35 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.55577684 |
| 36 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.55457231 |
| 37 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.50617467 |
| 38 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.43058884 |
| 39 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.42565566 |
| 40 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.40140034 |
| 41 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.39822343 |
| 42 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.38312626 |
| 43 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.32228721 |
| 44 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.31445391 |
| 45 | STAT3_19079543_ChIP-ChIP_MESCs_Mouse | 1.30042707 |
| 46 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.24417969 |
| 47 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.24388179 |
| 48 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.24048051 |
| 49 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.22929373 |
| 50 | VDR_22108803_ChIP-Seq_LS180_Human | 1.20418880 |
| 51 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.17541745 |
| 52 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.16325712 |
| 53 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.16273405 |
| 54 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.16114775 |
| 55 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.14924991 |
| 56 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.14828314 |
| 57 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.12858868 |
| 58 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.12542564 |
| 59 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.11925413 |
| 60 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.11078447 |
| 61 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.11040675 |
| 62 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.10608932 |
| 63 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.07434623 |
| 64 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.06928639 |
| 65 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.06198325 |
| 66 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.04735738 |
| 67 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.02923896 |
| 68 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.02371366 |
| 69 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.02371366 |
| 70 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.01913859 |
| 71 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.01571281 |
| 72 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.00840756 |
| 73 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 0.99758485 |
| 74 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.99004069 |
| 75 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.96759270 |
| 76 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 0.93542930 |
| 77 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.91653753 |
| 78 | ERA_21632823_ChIP-Seq_H3396_Human | 0.91439295 |
| 79 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.91203331 |
| 80 | P68_20966046_ChIP-Seq_HELA_Human | 0.90762819 |
| 81 | SOX2_22085726_ChIP-Seq_NPCs_Mouse | 0.90594429 |
| 82 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.89912582 |
| 83 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.88861027 |
| 84 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.88850524 |
| 85 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.88517663 |
| 86 | E2F1_17053090_ChIP-ChIP_MCF-7_Human | 0.87308487 |
| 87 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.85766622 |
| 88 | TP53_22127205_ChIP-Seq_IMR90_Human | 0.85376681 |
| 89 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 0.85089864 |
| 90 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.84907988 |
| 91 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.84489521 |
| 92 | AR_21572438_ChIP-Seq_LNCaP_Human | 0.83917319 |
| 93 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 0.83805224 |
| 94 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.83712171 |
| 95 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.83639861 |
| 96 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.83468922 |
| 97 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.83386825 |
| 98 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 0.82305321 |
| 99 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.81988495 |
| 100 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 0.81465542 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006292_abnormal_olfactory_placode | 6.91351859 |
| 2 | MP0009379_abnormal_foot_pigmentation | 5.63363449 |
| 3 | MP0000778_abnormal_nervous_system | 2.77840138 |
| 4 | MP0002163_abnormal_gland_morphology | 2.70700690 |
| 5 | MP0003283_abnormal_digestive_organ | 2.70556944 |
| 6 | MP0001529_abnormal_vocalization | 2.67235129 |
| 7 | MP0003011_delayed_dark_adaptation | 2.62763162 |
| 8 | MP0000631_abnormal_neuroendocrine_gland | 2.50189399 |
| 9 | MP0005645_abnormal_hypothalamus_physiol | 2.45817986 |
| 10 | MP0000049_abnormal_middle_ear | 2.34976779 |
| 11 | MP0001293_anophthalmia | 2.21179007 |
| 12 | MP0004885_abnormal_endolymph | 2.18629277 |
| 13 | MP0003879_abnormal_hair_cell | 2.14496913 |
| 14 | MP0002638_abnormal_pupillary_reflex | 2.06422098 |
| 15 | MP0006072_abnormal_retinal_apoptosis | 1.98056103 |
| 16 | MP0001286_abnormal_eye_development | 1.90146281 |
| 17 | MP0001905_abnormal_dopamine_level | 1.72343608 |
| 18 | MP0009046_muscle_twitch | 1.72236691 |
| 19 | MP0004147_increased_porphyrin_level | 1.70613361 |
| 20 | MP0002822_catalepsy | 1.69200169 |
| 21 | MP0002653_abnormal_ependyma_morphology | 1.66061184 |
| 22 | MP0000678_abnormal_parathyroid_gland | 1.63927265 |
| 23 | MP0000026_abnormal_inner_ear | 1.58975480 |
| 24 | MP0005671_abnormal_response_to | 1.57295283 |
| 25 | MP0005379_endocrine/exocrine_gland_phen | 1.54392492 |
| 26 | MP0001485_abnormal_pinna_reflex | 1.50632358 |
| 27 | MP0002282_abnormal_trachea_morphology | 1.42058104 |
| 28 | MP0003136_yellow_coat_color | 1.41233409 |
| 29 | MP0004142_abnormal_muscle_tone | 1.39081898 |
| 30 | MP0005646_abnormal_pituitary_gland | 1.36463032 |
| 31 | MP0002184_abnormal_innervation | 1.33609433 |
| 32 | MP0003938_abnormal_ear_development | 1.31258841 |
| 33 | MP0008789_abnormal_olfactory_epithelium | 1.31110137 |
| 34 | MP0002160_abnormal_reproductive_system | 1.29284723 |
| 35 | MP0002557_abnormal_social/conspecific_i | 1.27836284 |
| 36 | MP0001963_abnormal_hearing_physiology | 1.26450864 |
| 37 | MP0006276_abnormal_autonomic_nervous | 1.26361735 |
| 38 | MP0000566_synostosis | 1.25339187 |
| 39 | MP0002249_abnormal_larynx_morphology | 1.21326690 |
| 40 | MP0009053_abnormal_anal_canal | 1.20490671 |
| 41 | MP0005195_abnormal_posterior_eye | 1.18328000 |
| 42 | MP0002752_abnormal_somatic_nervous | 1.17973630 |
| 43 | MP0002928_abnormal_bile_duct | 1.17274794 |
| 44 | MP0000955_abnormal_spinal_cord | 1.16395043 |
| 45 | MP0005499_abnormal_olfactory_system | 1.15608880 |
| 46 | MP0005394_taste/olfaction_phenotype | 1.15608880 |
| 47 | MP0005386_behavior/neurological_phenoty | 1.14928431 |
| 48 | MP0004924_abnormal_behavior | 1.14928431 |
| 49 | MP0005423_abnormal_somatic_nervous | 1.13563516 |
| 50 | MP0001502_abnormal_circadian_rhythm | 1.10030799 |
| 51 | MP0002095_abnormal_skin_pigmentation | 1.09016040 |
| 52 | MP0005084_abnormal_gallbladder_morpholo | 1.08528676 |
| 53 | MP0002272_abnormal_nervous_system | 1.05732699 |
| 54 | MP0005083_abnormal_biliary_tract | 1.04374812 |
| 55 | MP0005451_abnormal_body_composition | 1.03455679 |
| 56 | MP0004130_abnormal_muscle_cell | 1.01582796 |
| 57 | MP0003787_abnormal_imprinting | 1.01473799 |
| 58 | MP0005253_abnormal_eye_physiology | 1.01378006 |
| 59 | MP0002234_abnormal_pharynx_morphology | 0.97751535 |
| 60 | MP0003942_abnormal_urinary_system | 0.96870926 |
| 61 | MP0000428_abnormal_craniofacial_morphol | 0.95720994 |
| 62 | MP0009745_abnormal_behavioral_response | 0.94078953 |
| 63 | MP0003880_abnormal_central_pattern | 0.92840494 |
| 64 | MP0000613_abnormal_salivary_gland | 0.91820612 |
| 65 | MP0005389_reproductive_system_phenotype | 0.90651811 |
| 66 | MP0005391_vision/eye_phenotype | 0.85289370 |
| 67 | MP0001542_abnormal_bone_strength | 0.84905989 |
| 68 | MP0004742_abnormal_vestibular_system | 0.84523138 |
| 69 | MP0002723_abnormal_immune_serum | 0.82815927 |
| 70 | MP0002063_abnormal_learning/memory/cond | 0.82349600 |
| 71 | MP0002132_abnormal_respiratory_system | 0.81859971 |
| 72 | MP0002697_abnormal_eye_size | 0.81329085 |
| 73 | MP0003755_abnormal_palate_morphology | 0.80848704 |
| 74 | MP0003635_abnormal_synaptic_transmissio | 0.77020158 |
| 75 | MP0008995_early_reproductive_senescence | 0.75700905 |
| 76 | MP0009250_abnormal_appendicular_skeleto | 0.75450847 |
| 77 | MP0002116_abnormal_craniofacial_bone | 0.74578015 |
| 78 | MP0005551_abnormal_eye_electrophysiolog | 0.73762679 |
| 79 | MP0002882_abnormal_neuron_morphology | 0.72225877 |
| 80 | MP0003195_calcinosis | 0.71894054 |
| 81 | MP0001727_abnormal_embryo_implantation | 0.71837999 |
| 82 | MP0003937_abnormal_limbs/digits/tail_de | 0.71822329 |
| 83 | MP0002152_abnormal_brain_morphology | 0.71385289 |
| 84 | MP0002876_abnormal_thyroid_physiology | 0.70699377 |
| 85 | MP0001800_abnormal_humoral_immune | 0.68991429 |
| 86 | MP0008872_abnormal_physiological_respon | 0.68036656 |
| 87 | MP0003122_maternal_imprinting | 0.65823255 |
| 88 | MP0002210_abnormal_sex_determination | 0.65668244 |
| 89 | MP0008875_abnormal_xenobiotic_pharmacok | 0.65593490 |
| 90 | MP0006036_abnormal_mitochondrial_physio | 0.65116791 |
| 91 | MP0005448_abnormal_energy_balance | 0.64943419 |
| 92 | MP0002136_abnormal_kidney_physiology | 0.64848330 |
| 93 | MP0002138_abnormal_hepatobiliary_system | 0.64839455 |
| 94 | MP0003123_paternal_imprinting | 0.64672728 |
| 95 | MP0001188_hyperpigmentation | 0.64625439 |
| 96 | MP0006035_abnormal_mitochondrial_morpho | 0.64009270 |
| 97 | MP0002233_abnormal_nose_morphology | 0.63582497 |
| 98 | MP0001324_abnormal_eye_pigmentation | 0.63470621 |
| 99 | MP0003861_abnormal_nervous_system | 0.62023426 |
| 100 | MP0002909_abnormal_adrenal_gland | 0.61617589 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Septo-optic dysplasia (HP:0100842) | 5.25016449 |
| 2 | Reticulocytopenia (HP:0001896) | 5.17832305 |
| 3 | 3-Methylglutaconic aciduria (HP:0003535) | 4.17988930 |
| 4 | Acute necrotizing encephalopathy (HP:0006965) | 4.01652270 |
| 5 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 3.94497037 |
| 6 | Growth hormone deficiency (HP:0000824) | 3.80531306 |
| 7 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.79052706 |
| 8 | Anophthalmia (HP:0000528) | 3.60848676 |
| 9 | Papilledema (HP:0001085) | 3.46822992 |
| 10 | Mitochondrial inheritance (HP:0001427) | 3.38178282 |
| 11 | Progressive macrocephaly (HP:0004481) | 3.37711546 |
| 12 | Optic nerve hypoplasia (HP:0000609) | 3.25832248 |
| 13 | Macrocytic anemia (HP:0001972) | 3.16027268 |
| 14 | Shawl scrotum (HP:0000049) | 3.06897133 |
| 15 | Hepatocellular necrosis (HP:0001404) | 3.04566357 |
| 16 | Deep palmar crease (HP:0006191) | 3.02381071 |
| 17 | Absent septum pellucidum (HP:0001331) | 3.01461988 |
| 18 | Morphological abnormality of the middle ear (HP:0008609) | 2.95446852 |
| 19 | Abnormality of the nasal septum (HP:0000419) | 2.89949441 |
| 20 | Acute encephalopathy (HP:0006846) | 2.89592013 |
| 21 | Lipid accumulation in hepatocytes (HP:0006561) | 2.82562148 |
| 22 | Lissencephaly (HP:0001339) | 2.81826887 |
| 23 | Sclerocornea (HP:0000647) | 2.76634100 |
| 24 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.69582799 |
| 25 | Increased CSF lactate (HP:0002490) | 2.66572546 |
| 26 | Pancreatic fibrosis (HP:0100732) | 2.62425781 |
| 27 | Partial agenesis of the corpus callosum (HP:0001338) | 2.54926996 |
| 28 | Pallor (HP:0000980) | 2.54138415 |
| 29 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.45092624 |
| 30 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.42018853 |
| 31 | Maternal diabetes (HP:0009800) | 2.41407904 |
| 32 | Absent thumb (HP:0009777) | 2.39874094 |
| 33 | Increased hepatocellular lipid droplets (HP:0006565) | 2.37315740 |
| 34 | Pancreatic cysts (HP:0001737) | 2.37086040 |
| 35 | Abnormality of the septum pellucidum (HP:0007375) | 2.34986858 |
| 36 | Colon cancer (HP:0003003) | 2.33444558 |
| 37 | Increased intramyocellular lipid droplets (HP:0012240) | 2.33378807 |
| 38 | Cortical visual impairment (HP:0100704) | 2.30910594 |
| 39 | Gastrointestinal stroma tumor (HP:0100723) | 2.30037210 |
| 40 | Morphological abnormality of the inner ear (HP:0011390) | 2.27305737 |
| 41 | Rhabdomyosarcoma (HP:0002859) | 2.26264157 |
| 42 | Increased muscle lipid content (HP:0009058) | 2.25574322 |
| 43 | Congenital stationary night blindness (HP:0007642) | 2.23720037 |
| 44 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.23600633 |
| 45 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.23146338 |
| 46 | Hepatic necrosis (HP:0002605) | 2.22589251 |
| 47 | Abnormality of purine metabolism (HP:0004352) | 2.21142545 |
| 48 | Type II lissencephaly (HP:0007260) | 2.18529343 |
| 49 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 2.17409200 |
| 50 | Bilateral microphthalmos (HP:0007633) | 2.16420290 |
| 51 | Hypoplasia of the uterus (HP:0000013) | 2.15388164 |
| 52 | Enlarged kidneys (HP:0000105) | 2.14625840 |
| 53 | Abnormality of the prostate (HP:0008775) | 2.14061649 |
| 54 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 2.13839089 |
| 55 | Cerebral edema (HP:0002181) | 2.12809197 |
| 56 | Agitation (HP:0000713) | 2.09877977 |
| 57 | Humeroradial synostosis (HP:0003041) | 2.09480703 |
| 58 | Synostosis involving the elbow (HP:0003938) | 2.09480703 |
| 59 | Long nose (HP:0003189) | 2.02846124 |
| 60 | Irregular vertebral endplates (HP:0003301) | 1.99551518 |
| 61 | Breast hypoplasia (HP:0003187) | 1.99277457 |
| 62 | Aplasia/Hypoplasia of the nipples (HP:0006709) | 1.97208096 |
| 63 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.95816473 |
| 64 | Pendular nystagmus (HP:0012043) | 1.93797370 |
| 65 | True hermaphroditism (HP:0010459) | 1.91687940 |
| 66 | Severe short stature (HP:0003510) | 1.89461763 |
| 67 | Abnormality of the vertebral endplates (HP:0005106) | 1.89303542 |
| 68 | Thyroid-stimulating hormone excess (HP:0002925) | 1.88648747 |
| 69 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.88541537 |
| 70 | Abnormal pancreas size (HP:0012094) | 1.87032240 |
| 71 | Hypoplasia of the brainstem (HP:0002365) | 1.83393546 |
| 72 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 1.83393546 |
| 73 | Optic disc pallor (HP:0000543) | 1.82616650 |
| 74 | Anterior segment dysgenesis (HP:0007700) | 1.82017871 |
| 75 | Hypoplastic pelvis (HP:0008839) | 1.80650238 |
| 76 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.79475240 |
| 77 | Midline defect of the nose (HP:0004122) | 1.79407520 |
| 78 | Trigonocephaly (HP:0000243) | 1.78824097 |
| 79 | Abnormal number of erythroid precursors (HP:0012131) | 1.78733321 |
| 80 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.77826488 |
| 81 | Hepatoblastoma (HP:0002884) | 1.76876189 |
| 82 | Stenosis of the external auditory canal (HP:0000402) | 1.76642108 |
| 83 | Turricephaly (HP:0000262) | 1.74513856 |
| 84 | Testicular atrophy (HP:0000029) | 1.73818375 |
| 85 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 1.72921715 |
| 86 | Neoplasm of striated muscle (HP:0009728) | 1.72772916 |
| 87 | Palpebral edema (HP:0100540) | 1.72710625 |
| 88 | Patellar aplasia (HP:0006443) | 1.70463697 |
| 89 | Asplenia (HP:0001746) | 1.69938932 |
| 90 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.68661379 |
| 91 | Microvesicular hepatic steatosis (HP:0001414) | 1.68344088 |
| 92 | Dandy-Walker malformation (HP:0001305) | 1.67350449 |
| 93 | Lymphopenia (HP:0001888) | 1.65004948 |
| 94 | Oligodactyly (hands) (HP:0001180) | 1.64883343 |
| 95 | Increased serum lactate (HP:0002151) | 1.64555241 |
| 96 | Pachygyria (HP:0001302) | 1.64124694 |
| 97 | Abnormality of nucleobase metabolism (HP:0010932) | 1.63170803 |
| 98 | Flat capital femoral epiphysis (HP:0003370) | 1.62646445 |
| 99 | Synostosis of carpal bones (HP:0005048) | 1.62269814 |
| 100 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 1.62085578 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EPHB2 | 4.70822644 |
| 2 | VRK1 | 3.72495921 |
| 3 | VRK2 | 3.46487311 |
| 4 | SMG1 | 3.20368750 |
| 5 | TLK1 | 3.07270045 |
| 6 | ZAK | 2.95460185 |
| 7 | SIK2 | 2.89407775 |
| 8 | CDK19 | 2.57195539 |
| 9 | BLK | 2.51115028 |
| 10 | MAP3K11 | 2.32768786 |
| 11 | CDC7 | 2.25826788 |
| 12 | DYRK1B | 2.15151714 |
| 13 | NTRK2 | 2.04801542 |
| 14 | OXSR1 | 2.00119577 |
| 15 | MAP4K1 | 1.86059452 |
| 16 | PIK3CG | 1.64628047 |
| 17 | WNK4 | 1.50558631 |
| 18 | IRAK4 | 1.46524930 |
| 19 | MAP4K2 | 1.46148322 |
| 20 | RPS6KA5 | 1.43017415 |
| 21 | FRK | 1.40569459 |
| 22 | ERBB2 | 1.31087847 |
| 23 | UHMK1 | 1.29869739 |
| 24 | AURKA | 1.28631551 |
| 25 | PLK2 | 1.24737449 |
| 26 | CAMK1 | 1.23016465 |
| 27 | BRAF | 1.22525744 |
| 28 | STK16 | 1.22049243 |
| 29 | CHEK2 | 1.16454264 |
| 30 | EPHA4 | 1.14822194 |
| 31 | TAF1 | 1.12987246 |
| 32 | STK4 | 1.12601115 |
| 33 | RPS6KA4 | 1.11550567 |
| 34 | DAPK3 | 1.09655564 |
| 35 | GRK1 | 1.07131941 |
| 36 | ARAF | 1.06646054 |
| 37 | PKN1 | 1.05065460 |
| 38 | ADRBK2 | 0.96914857 |
| 39 | AURKB | 0.90321554 |
| 40 | CAMKK2 | 0.88654004 |
| 41 | PLK3 | 0.87537405 |
| 42 | TEC | 0.86110572 |
| 43 | PRKCZ | 0.86056959 |
| 44 | STK11 | 0.85212075 |
| 45 | CAMK4 | 0.85074014 |
| 46 | CASK | 0.82541861 |
| 47 | MARK2 | 0.82509085 |
| 48 | MAP3K9 | 0.81497539 |
| 49 | WNK3 | 0.78936516 |
| 50 | INSRR | 0.78785845 |
| 51 | GRK6 | 0.77780542 |
| 52 | SYK | 0.77170578 |
| 53 | BTK | 0.71273760 |
| 54 | MOS | 0.69595150 |
| 55 | CDK14 | 0.69317793 |
| 56 | RPS6KA6 | 0.68062697 |
| 57 | MARK1 | 0.66984397 |
| 58 | PIK3CA | 0.65954898 |
| 59 | RPS6KA2 | 0.65177753 |
| 60 | PRKCQ | 0.64547339 |
| 61 | NUAK1 | 0.64520703 |
| 62 | PAK3 | 0.64427513 |
| 63 | PRKD2 | 0.64335503 |
| 64 | RPS6KC1 | 0.62568638 |
| 65 | RPS6KL1 | 0.62568638 |
| 66 | JAK3 | 0.62389904 |
| 67 | CDK15 | 0.61927355 |
| 68 | PIM1 | 0.61860887 |
| 69 | SGK2 | 0.61166545 |
| 70 | DYRK2 | 0.58862944 |
| 71 | MAPK15 | 0.54859496 |
| 72 | ITK | 0.53281437 |
| 73 | NME1 | 0.53242560 |
| 74 | INSR | 0.52033185 |
| 75 | CDK18 | 0.51231858 |
| 76 | CSNK2A2 | 0.50883059 |
| 77 | MAPK13 | 0.48986143 |
| 78 | IKBKB | 0.48269853 |
| 79 | STK39 | 0.47606009 |
| 80 | CDK11A | 0.46746495 |
| 81 | MAPKAPK5 | 0.46161298 |
| 82 | HIPK2 | 0.45658456 |
| 83 | BRSK2 | 0.43550727 |
| 84 | MAP3K1 | 0.43449726 |
| 85 | PAK1 | 0.43012274 |
| 86 | PRKCD | 0.42553687 |
| 87 | NTRK1 | 0.41302621 |
| 88 | MAP2K2 | 0.40741784 |
| 89 | PAK6 | 0.40538304 |
| 90 | BCKDK | 0.39185258 |
| 91 | PRKACA | 0.38210719 |
| 92 | CSK | 0.37356472 |
| 93 | LCK | 0.36576157 |
| 94 | NEK1 | 0.35743157 |
| 95 | KIT | 0.34775001 |
| 96 | MATK | 0.34304173 |
| 97 | LYN | 0.33027676 |
| 98 | SGK223 | 0.32209978 |
| 99 | SGK494 | 0.32209978 |
| 100 | WNK1 | 0.31869796 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.63408995 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.49113677 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 4.04310326 |
| 4 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 3.82992725 |
| 5 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 3.33058429 |
| 6 | Sulfur relay system_Homo sapiens_hsa04122 | 2.75001291 |
| 7 | Alcoholism_Homo sapiens_hsa05034 | 2.73275725 |
| 8 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.70808145 |
| 9 | Alzheimers disease_Homo sapiens_hsa05010 | 2.49095426 |
| 10 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.39715819 |
| 11 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.32839665 |
| 12 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.25487485 |
| 13 | Huntingtons disease_Homo sapiens_hsa05016 | 2.18148624 |
| 14 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.10957837 |
| 15 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.83781290 |
| 16 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.78798529 |
| 17 | Homologous recombination_Homo sapiens_hsa03440 | 1.74549689 |
| 18 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.62119146 |
| 19 | Proteasome_Homo sapiens_hsa03050 | 1.61831889 |
| 20 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.54386293 |
| 21 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.39504906 |
| 22 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.26138842 |
| 23 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.17502722 |
| 24 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.17169627 |
| 25 | Asthma_Homo sapiens_hsa05310 | 1.14661343 |
| 26 | Allograft rejection_Homo sapiens_hsa05330 | 1.11920939 |
| 27 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.10554466 |
| 28 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.05395441 |
| 29 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.02175155 |
| 30 | Mismatch repair_Homo sapiens_hsa03430 | 0.95391800 |
| 31 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.94932611 |
| 32 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.93168878 |
| 33 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.92588964 |
| 34 | Phototransduction_Homo sapiens_hsa04744 | 0.92552544 |
| 35 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.91494201 |
| 36 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.86882892 |
| 37 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.86126072 |
| 38 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.84834115 |
| 39 | Cocaine addiction_Homo sapiens_hsa05030 | 0.83618620 |
| 40 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.83515412 |
| 41 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.82869940 |
| 42 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.80319223 |
| 43 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.77360794 |
| 44 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.76439626 |
| 45 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.75838401 |
| 46 | Salivary secretion_Homo sapiens_hsa04970 | 0.75137171 |
| 47 | Phagosome_Homo sapiens_hsa04145 | 0.73166075 |
| 48 | Retinol metabolism_Homo sapiens_hsa00830 | 0.70357165 |
| 49 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.66897337 |
| 50 | Insulin secretion_Homo sapiens_hsa04911 | 0.65502137 |
| 51 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.61869050 |
| 52 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.61392588 |
| 53 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.61127173 |
| 54 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.60039630 |
| 55 | Axon guidance_Homo sapiens_hsa04360 | 0.56262394 |
| 56 | Protein export_Homo sapiens_hsa03060 | 0.53770058 |
| 57 | Morphine addiction_Homo sapiens_hsa05032 | 0.53522358 |
| 58 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.50665005 |
| 59 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.50066018 |
| 60 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.49129960 |
| 61 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.45806798 |
| 62 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.45721711 |
| 63 | Purine metabolism_Homo sapiens_hsa00230 | 0.45484879 |
| 64 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.44217250 |
| 65 | Basal transcription factors_Homo sapiens_hsa03022 | 0.43246473 |
| 66 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.43002551 |
| 67 | Bile secretion_Homo sapiens_hsa04976 | 0.41802562 |
| 68 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.40549804 |
| 69 | Peroxisome_Homo sapiens_hsa04146 | 0.38318136 |
| 70 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.37965190 |
| 71 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.37647287 |
| 72 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.37544493 |
| 73 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.36588585 |
| 74 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.36440332 |
| 75 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.36135021 |
| 76 | Metabolic pathways_Homo sapiens_hsa01100 | 0.35561133 |
| 77 | Leishmaniasis_Homo sapiens_hsa05140 | 0.35298706 |
| 78 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.35139318 |
| 79 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.34885327 |
| 80 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.34424689 |
| 81 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.33939455 |
| 82 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.33621041 |
| 83 | Olfactory transduction_Homo sapiens_hsa04740 | 0.32371504 |
| 84 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.31723375 |
| 85 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.31642481 |
| 86 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.31599261 |
| 87 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.31128251 |
| 88 | Melanoma_Homo sapiens_hsa05218 | 0.30592817 |
| 89 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.29837316 |
| 90 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.29293766 |
| 91 | Circadian entrainment_Homo sapiens_hsa04713 | 0.29152358 |
| 92 | Melanogenesis_Homo sapiens_hsa04916 | 0.28257996 |
| 93 | Spliceosome_Homo sapiens_hsa03040 | 0.27008091 |
| 94 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.25552226 |
| 95 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.24755844 |
| 96 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.24517331 |
| 97 | Gap junction_Homo sapiens_hsa04540 | 0.24477864 |
| 98 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.22683584 |
| 99 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.21798572 |
| 100 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.21593624 |

