

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 8.94715456 |
| 2 | diacylglycerol metabolic process (GO:0046339) | 8.54560579 |
| 3 | behavioral response to nicotine (GO:0035095) | 8.41856137 |
| 4 | dopaminergic neuron differentiation (GO:0071542) | 8.35425739 |
| 5 | cellular response to prostaglandin stimulus (GO:0071379) | 8.22935674 |
| 6 | body morphogenesis (GO:0010171) | 7.83038510 |
| 7 | ganglion development (GO:0061548) | 7.47851432 |
| 8 | enteric nervous system development (GO:0048484) | 7.06351873 |
| 9 | post-embryonic morphogenesis (GO:0009886) | 6.73604677 |
| 10 | cellular response to zinc ion (GO:0071294) | 6.58057280 |
| 11 | cell migration in hindbrain (GO:0021535) | 6.55930763 |
| 12 | positive regulation of cAMP-mediated signaling (GO:0043950) | 6.35860918 |
| 13 | regulation of respiratory gaseous exchange (GO:0043576) | 6.27656427 |
| 14 | adrenergic receptor signaling pathway (GO:0071875) | 6.21324667 |
| 15 | cAMP biosynthetic process (GO:0006171) | 6.08972502 |
| 16 | response to prostaglandin E (GO:0034695) | 6.08184365 |
| 17 | negative regulation of multicellular organism growth (GO:0040015) | 6.03554824 |
| 18 | ectodermal placode formation (GO:0060788) | 5.81379269 |
| 19 | norepinephrine metabolic process (GO:0042415) | 5.75172511 |
| 20 | regulation of non-canonical Wnt signaling pathway (GO:2000050) | 5.65275135 |
| 21 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 5.43099215 |
| 22 | surfactant homeostasis (GO:0043129) | 5.21794232 |
| 23 | alkaloid metabolic process (GO:0009820) | 5.17445217 |
| 24 | dopamine biosynthetic process (GO:0042416) | 4.92567586 |
| 25 | synaptic transmission, cholinergic (GO:0007271) | 4.84757060 |
| 26 | primary amino compound metabolic process (GO:1901160) | 4.73849634 |
| 27 | regulation of secondary heart field cardioblast proliferation (GO:0003266) | 4.57671696 |
| 28 | regulation of cardioblast proliferation (GO:0003264) | 4.57671696 |
| 29 | response to prostaglandin (GO:0034694) | 4.56312758 |
| 30 | activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171) | 4.51936571 |
| 31 | cellular response to monoamine stimulus (GO:0071868) | 4.51440110 |
| 32 | cellular response to catecholamine stimulus (GO:0071870) | 4.51440110 |
| 33 | neuronal action potential propagation (GO:0019227) | 4.44096680 |
| 34 | protein kinase C-activating G-protein coupled receptor signaling pathway (GO:0007205) | 4.43950272 |
| 35 | regulation of respiratory system process (GO:0044065) | 4.42628200 |
| 36 | cellular response to BMP stimulus (GO:0071773) | 4.25841539 |
| 37 | response to BMP (GO:0071772) | 4.25841539 |
| 38 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 4.21635017 |
| 39 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 4.12327247 |
| 40 | negative regulation of cell cycle arrest (GO:0071157) | 4.10333659 |
| 41 | catechol-containing compound biosynthetic process (GO:0009713) | 4.07397163 |
| 42 | catecholamine biosynthetic process (GO:0042423) | 4.07397163 |
| 43 | chemical homeostasis within a tissue (GO:0048875) | 3.99085763 |
| 44 | dopamine receptor signaling pathway (GO:0007212) | 3.98537876 |
| 45 | cellular response to glucagon stimulus (GO:0071377) | 3.98304026 |
| 46 | calcium-mediated signaling using intracellular calcium source (GO:0035584) | 3.98160149 |
| 47 | regulation of neuron projection regeneration (GO:0070570) | 3.89452740 |
| 48 | regulation of axon regeneration (GO:0048679) | 3.89452740 |
| 49 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 3.83534839 |
| 50 | response to catecholamine (GO:0071869) | 3.79071383 |
| 51 | response to monoamine (GO:0071867) | 3.79071383 |
| 52 | positive regulation of cell cycle G2/M phase transition (GO:1902751) | 3.77797607 |
| 53 | positive regulation of G2/M transition of mitotic cell cycle (GO:0010971) | 3.77797607 |
| 54 | coronary vasculature morphogenesis (GO:0060977) | 3.70419452 |
| 55 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.70006348 |
| 56 | neural crest cell migration (GO:0001755) | 3.69138867 |
| 57 | organic cation transport (GO:0015695) | 3.64095516 |
| 58 | positive regulation of osteoclast differentiation (GO:0045672) | 3.56957367 |
| 59 | activation of adenylate cyclase activity (GO:0007190) | 3.51515563 |
| 60 | neuromuscular synaptic transmission (GO:0007274) | 3.49538447 |
| 61 | genetic imprinting (GO:0071514) | 3.47687497 |
| 62 | protein maturation by protein folding (GO:0022417) | 3.43564695 |
| 63 | regulation of cAMP-mediated signaling (GO:0043949) | 3.41211922 |
| 64 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 3.38956034 |
| 65 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:0043 | 3.38818314 |
| 66 | negative regulation of cardiac muscle cell apoptotic process (GO:0010667) | 3.38199691 |
| 67 | tongue development (GO:0043586) | 3.30583680 |
| 68 | cellular response to fatty acid (GO:0071398) | 3.28336828 |
| 69 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 3.25630976 |
| 70 | cell communication by electrical coupling (GO:0010644) | 3.15510687 |
| 71 | phenol-containing compound catabolic process (GO:0019336) | 3.14621950 |
| 72 | negative regulation of phosphoprotein phosphatase activity (GO:0032515) | 3.13381850 |
| 73 | cyclic purine nucleotide metabolic process (GO:0052652) | 3.10966264 |
| 74 | positive regulation of adenylate cyclase activity (GO:0045762) | 3.08824122 |
| 75 | cAMP metabolic process (GO:0046058) | 3.07706637 |
| 76 | tyrosine metabolic process (GO:0006570) | 3.05027755 |
| 77 | peripheral nervous system neuron development (GO:0048935) | 3.03984000 |
| 78 | response to glucagon (GO:0033762) | 3.01762242 |
| 79 | catecholamine transport (GO:0051937) | 3.01719704 |
| 80 | catechol-containing compound metabolic process (GO:0009712) | 3.01079314 |
| 81 | catecholamine metabolic process (GO:0006584) | 3.01079314 |
| 82 | cellular response to ketone (GO:1901655) | 3.00438858 |
| 83 | dopamine metabolic process (GO:0042417) | 2.96879423 |
| 84 | cyclic nucleotide biosynthetic process (GO:0009190) | 2.93496193 |
| 85 | toxin metabolic process (GO:0009404) | 2.93200493 |
| 86 | SMAD protein complex assembly (GO:0007183) | 2.92731280 |
| 87 | cellular zinc ion homeostasis (GO:0006882) | 2.90579398 |
| 88 | polyamine biosynthetic process (GO:0006596) | 2.82654034 |
| 89 | replacement ossification (GO:0036075) | 2.81741197 |
| 90 | endochondral ossification (GO:0001958) | 2.81741197 |
| 91 | cell differentiation in hindbrain (GO:0021533) | 2.80473590 |
| 92 | regulation of neurotransmitter secretion (GO:0046928) | 2.78827374 |
| 93 | apoptotic process involved in morphogenesis (GO:0060561) | 2.78413315 |
| 94 | positive regulation of transcription regulatory region DNA binding (GO:2000679) | 2.75186738 |
| 95 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 2.74027781 |
| 96 | regulation of synaptic vesicle exocytosis (GO:2000300) | 2.72978392 |
| 97 | bone development (GO:0060348) | 2.72307968 |
| 98 | water transport (GO:0006833) | 2.70591691 |
| 99 | sympathetic nervous system development (GO:0048485) | 11.0430120 |
| 100 | response to parathyroid hormone (GO:0071107) | 10.6891786 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 3.57723988 |
| 2 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.53468426 |
| 3 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 3.30804824 |
| 4 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 3.22926704 |
| 5 | ZNF263_19887448_ChIP-Seq_K562_Human | 3.12893878 |
| 6 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 3.09850882 |
| 7 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 3.09850882 |
| 8 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.96435376 |
| 9 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.89252688 |
| 10 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.86544033 |
| 11 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.83669366 |
| 12 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.80810812 |
| 13 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.80204297 |
| 14 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 2.59337762 |
| 15 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 2.56508978 |
| 16 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.53850288 |
| 17 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.45121954 |
| 18 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.43418706 |
| 19 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.41063974 |
| 20 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.34143943 |
| 21 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.30985916 |
| 22 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.30449931 |
| 23 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 2.28934256 |
| 24 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 2.26190910 |
| 25 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.23700350 |
| 26 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.21639530 |
| 27 | VDR_22108803_ChIP-Seq_LS180_Human | 2.12849785 |
| 28 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.09550873 |
| 29 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.03610221 |
| 30 | KDM2B_26808549_Chip-Seq_K562_Human | 1.94895165 |
| 31 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.94727505 |
| 32 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.92844279 |
| 33 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.85834495 |
| 34 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.80648642 |
| 35 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.72095156 |
| 36 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.64950927 |
| 37 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.62328706 |
| 38 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.58970143 |
| 39 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.58724012 |
| 40 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.58259072 |
| 41 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.56286916 |
| 42 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.54527525 |
| 43 | GATA1_19941826_ChIP-Seq_K562_Human | 1.53680143 |
| 44 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.44928177 |
| 45 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.41664820 |
| 46 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.41635155 |
| 47 | * MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 1.41600600 |
| 48 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.35309022 |
| 49 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.33456696 |
| 50 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.32639287 |
| 51 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.27872446 |
| 52 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.26018394 |
| 53 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.25638157 |
| 54 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.24948925 |
| 55 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.20888429 |
| 56 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.20731560 |
| 57 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.20054146 |
| 58 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.19174091 |
| 59 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.16571631 |
| 60 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.15221410 |
| 61 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.09723770 |
| 62 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.09314719 |
| 63 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.09228081 |
| 64 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.08468314 |
| 65 | STAT3_19079543_ChIP-ChIP_MESCs_Mouse | 1.06793687 |
| 66 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.03914837 |
| 67 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.01866948 |
| 68 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.01281272 |
| 69 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.00372370 |
| 70 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.00361952 |
| 71 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.99158513 |
| 72 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.97624255 |
| 73 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 0.95495812 |
| 74 | * PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.92919158 |
| 75 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.92583162 |
| 76 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.91955774 |
| 77 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.91426108 |
| 78 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.87831832 |
| 79 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.87688567 |
| 80 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.87189375 |
| 81 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.87113579 |
| 82 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 0.86673140 |
| 83 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.86548278 |
| 84 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 0.86311644 |
| 85 | PPARD_21283829_ChIP-Seq_MYOFIBROBLAST_Human | 0.86178189 |
| 86 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 0.85916933 |
| 87 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.85278003 |
| 88 | * KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.84266496 |
| 89 | P300_19829295_ChIP-Seq_ESCs_Human | 0.83889894 |
| 90 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.83472837 |
| 91 | MYC_19915707_ChIP-ChIP_AK7_Human | 0.83208379 |
| 92 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.82860685 |
| 93 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.81603326 |
| 94 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.80635738 |
| 95 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.78663795 |
| 96 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.77608446 |
| 97 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.77128202 |
| 98 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 0.76434345 |
| 99 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.76412835 |
| 100 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 0.75960537 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002638_abnormal_pupillary_reflex | 7.69736996 |
| 2 | MP0003787_abnormal_imprinting | 7.00465781 |
| 3 | MP0003123_paternal_imprinting | 6.83077855 |
| 4 | MP0005645_abnormal_hypothalamus_physiol | 5.25619663 |
| 5 | MP0003122_maternal_imprinting | 5.21523122 |
| 6 | MP0010386_abnormal_urinary_bladder | 4.85782262 |
| 7 | MP0008877_abnormal_DNA_methylation | 4.46635605 |
| 8 | MP0004130_abnormal_muscle_cell | 2.71051164 |
| 9 | MP0002822_catalepsy | 2.64576649 |
| 10 | MP0000003_abnormal_adipose_tissue | 2.38907943 |
| 11 | MP0003121_genomic_imprinting | 2.13454545 |
| 12 | MP0002751_abnormal_autonomic_nervous | 2.09465694 |
| 13 | MP0004043_abnormal_pH_regulation | 2.01808415 |
| 14 | MP0002909_abnormal_adrenal_gland | 1.98977875 |
| 15 | MP0009046_muscle_twitch | 1.78566768 |
| 16 | MP0005647_abnormal_sex_gland | 1.68015208 |
| 17 | MP0000538_abnormal_urinary_bladder | 1.66936758 |
| 18 | MP0003959_abnormal_lean_body | 1.66713883 |
| 19 | MP0001727_abnormal_embryo_implantation | 1.57402689 |
| 20 | MP0001270_distended_abdomen | 1.52377966 |
| 21 | MP0009745_abnormal_behavioral_response | 1.46711824 |
| 22 | MP0005085_abnormal_gallbladder_physiolo | 1.45264123 |
| 23 | MP0003195_calcinosis | 1.41244426 |
| 24 | MP0005623_abnormal_meninges_morphology | 1.41169644 |
| 25 | MP0005167_abnormal_blood-brain_barrier | 1.32249951 |
| 26 | MP0000230_abnormal_systemic_arterial | 1.31576141 |
| 27 | MP0001765_abnormal_ion_homeostasis | 1.27244516 |
| 28 | MP0002127_abnormal_cardiovascular_syste | 1.25826856 |
| 29 | MP0003638_abnormal_response/metabolism_ | 1.24179065 |
| 30 | MP0003635_abnormal_synaptic_transmissio | 1.22596172 |
| 31 | MP0000751_myopathy | 1.20137166 |
| 32 | MP0004859_abnormal_synaptic_plasticity | 1.15500925 |
| 33 | MP0005375_adipose_tissue_phenotype | 1.13631919 |
| 34 | MP0005197_abnormal_uvea_morphology | 1.10726482 |
| 35 | MP0005584_abnormal_enzyme/coenzyme_acti | 1.07534618 |
| 36 | MP0003942_abnormal_urinary_system | 1.07103623 |
| 37 | MP0002009_preneoplasia | 1.01455832 |
| 38 | MP0004270_analgesia | 0.98394213 |
| 39 | MP0001905_abnormal_dopamine_level | 0.97819099 |
| 40 | MP0005360_urolithiasis | 0.96333012 |
| 41 | MP0001756_abnormal_urination | 0.95923723 |
| 42 | MP0009840_abnormal_foam_cell | 0.92846323 |
| 43 | MP0006138_congestive_heart_failure | 0.92776656 |
| 44 | MP0009672_abnormal_birth_weight | 0.91785573 |
| 45 | MP0002064_seizures | 0.89959555 |
| 46 | MP0001968_abnormal_touch/_nociception | 0.89283829 |
| 47 | MP0004858_abnormal_nervous_system | 0.86853876 |
| 48 | MP0005319_abnormal_enzyme/_coenzyme | 0.85697749 |
| 49 | MP0009703_decreased_birth_body | 0.84654102 |
| 50 | MP0002971_abnormal_brown_adipose | 0.83182693 |
| 51 | MP0006276_abnormal_autonomic_nervous | 0.83006504 |
| 52 | MP0002063_abnormal_learning/memory/cond | 0.80944652 |
| 53 | MP0002139_abnormal_hepatobiliary_system | 0.80285404 |
| 54 | MP0005636_abnormal_mineral_homeostasis | 0.77921578 |
| 55 | MP0002272_abnormal_nervous_system | 0.77100911 |
| 56 | MP0002572_abnormal_emotion/affect_behav | 0.76633816 |
| 57 | MP0004085_abnormal_heartbeat | 0.75786808 |
| 58 | MP0000749_muscle_degeneration | 0.72163252 |
| 59 | MP0003631_nervous_system_phenotype | 0.72036739 |
| 60 | MP0002733_abnormal_thermal_nociception | 0.70588511 |
| 61 | MP0003633_abnormal_nervous_system | 0.68904558 |
| 62 | MP0003948_abnormal_gas_homeostasis | 0.68569023 |
| 63 | MP0003632_abnormal_nervous_system | 0.67614861 |
| 64 | MP0003252_abnormal_bile_duct | 0.65905948 |
| 65 | MP0003567_abnormal_fetal_cardiomyocyte | 0.65762283 |
| 66 | MP0003953_abnormal_hormone_level | 0.65664406 |
| 67 | MP0002067_abnormal_sensory_capabilities | 0.65381076 |
| 68 | MP0009643_abnormal_urine_homeostasis | 0.64911773 |
| 69 | MP0002163_abnormal_gland_morphology | 0.61837577 |
| 70 | MP0001943_abnormal_respiration | 0.61800049 |
| 71 | MP0001177_atelectasis | 0.60784610 |
| 72 | MP0000762_abnormal_tongue_morphology | 0.60545002 |
| 73 | MP0000631_abnormal_neuroendocrine_gland | 0.59326720 |
| 74 | MP0000249_abnormal_blood_vessel | 0.56246214 |
| 75 | MP0001970_abnormal_pain_threshold | 0.56051070 |
| 76 | MP0008872_abnormal_physiological_respon | 0.55109296 |
| 77 | MP0005083_abnormal_biliary_tract | 0.54241859 |
| 78 | MP0002060_abnormal_skin_morphology | 0.54162453 |
| 79 | MP0004885_abnormal_endolymph | 0.53367447 |
| 80 | MP0002069_abnormal_eating/drinking_beha | 0.52412876 |
| 81 | MP0003279_aneurysm | 0.52365616 |
| 82 | MP0005365_abnormal_bile_salt | 0.51059711 |
| 83 | MP0002138_abnormal_hepatobiliary_system | 0.50867919 |
| 84 | MP0002066_abnormal_motor_capabilities/c | 0.49128596 |
| 85 | MP0000955_abnormal_spinal_cord | 0.48792024 |
| 86 | MP0002078_abnormal_glucose_homeostasis | 0.47816537 |
| 87 | MP0010329_abnormal_lipoprotein_level | 0.47793182 |
| 88 | MP0004134_abnormal_chest_morphology | 0.47228986 |
| 89 | MP0002082_postnatal_lethality | 0.46097121 |
| 90 | MP0010770_preweaning_lethality | 0.46097121 |
| 91 | MP0002152_abnormal_brain_morphology | 0.45906490 |
| 92 | MP0001440_abnormal_grooming_behavior | 0.45609772 |
| 93 | MP0004811_abnormal_neuron_physiology | 0.45211854 |
| 94 | MP0009115_abnormal_fat_cell | 0.44508026 |
| 95 | MP0008874_decreased_physiological_sensi | 0.44142289 |
| 96 | MP0005464_abnormal_platelet_physiology | 0.43490857 |
| 97 | MP0001529_abnormal_vocalization | 0.42179369 |
| 98 | MP0005334_abnormal_fat_pad | 0.41908554 |
| 99 | MP0002734_abnormal_mechanical_nocicepti | 0.41523260 |
| 100 | MP0008770_decreased_survivor_rate | 0.40958858 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 9.02451621 |
| 2 | Enlarged penis (HP:0000040) | 8.60404803 |
| 3 | Menstrual irregularities (HP:0000858) | 8.12258608 |
| 4 | Agitation (HP:0000713) | 7.07917070 |
| 5 | Hyperthyroidism (HP:0000836) | 6.75757974 |
| 6 | Macroorchidism (HP:0000053) | 6.42104627 |
| 7 | Steatorrhea (HP:0002570) | 6.21503690 |
| 8 | Growth hormone excess (HP:0000845) | 6.07157577 |
| 9 | Rhinitis (HP:0012384) | 6.06095144 |
| 10 | Hypercortisolism (HP:0001578) | 5.44252616 |
| 11 | Hyperphosphatemia (HP:0002905) | 5.23248681 |
| 12 | Fat malabsorption (HP:0002630) | 5.08766101 |
| 13 | Testicular neoplasm (HP:0010788) | 5.03725779 |
| 14 | Restlessness (HP:0000711) | 4.96096308 |
| 15 | Hyperparathyroidism (HP:0000843) | 4.80986448 |
| 16 | Cranial hyperostosis (HP:0004437) | 4.79653407 |
| 17 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 4.74771052 |
| 18 | Striae distensae (HP:0001065) | 4.71757616 |
| 19 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 4.18228335 |
| 20 | Hypothermia (HP:0002045) | 4.11190810 |
| 21 | Exotropia (HP:0000577) | 4.00550489 |
| 22 | Amblyopia (HP:0000646) | 3.82702833 |
| 23 | Hypoventilation (HP:0002791) | 3.79711352 |
| 24 | Thickened calvaria (HP:0002684) | 3.62525452 |
| 25 | Basal ganglia calcification (HP:0002135) | 3.60972636 |
| 26 | Adrenal overactivity (HP:0002717) | 3.40504897 |
| 27 | Pathologic fracture (HP:0002756) | 3.29598680 |
| 28 | Decreased circulating renin level (HP:0003351) | 3.21841261 |
| 29 | Polycythemia (HP:0001901) | 2.95609771 |
| 30 | Goiter (HP:0000853) | 2.94482737 |
| 31 | Limb dystonia (HP:0002451) | 2.89792004 |
| 32 | Hyperactive renin-angiotensin system (HP:0000841) | 2.85035281 |
| 33 | Anxiety (HP:0000739) | 2.72381807 |
| 34 | Hypophosphatemia (HP:0002148) | 2.67410718 |
| 35 | Depression (HP:0000716) | 2.65929356 |
| 36 | Truncal obesity (HP:0001956) | 2.61254048 |
| 37 | Osteopenia (HP:0000938) | 2.60736397 |
| 38 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.50000519 |
| 39 | Myokymia (HP:0002411) | 2.49530080 |
| 40 | External ophthalmoplegia (HP:0000544) | 2.48542439 |
| 41 | Hyperpituitarism (HP:0010514) | 2.43631470 |
| 42 | Short metatarsal (HP:0010743) | 2.43467856 |
| 43 | Hypokalemic alkalosis (HP:0001949) | 2.43350150 |
| 44 | Craniofacial hyperostosis (HP:0004493) | 2.40362281 |
| 45 | Intestinal polyposis (HP:0200008) | 2.39796433 |
| 46 | Limb hypertonia (HP:0002509) | 2.36768806 |
| 47 | Lack of skin elasticity (HP:0100679) | 2.30628232 |
| 48 | Generalized hyperpigmentation (HP:0007440) | 2.29808915 |
| 49 | Neuroblastic tumors (HP:0004376) | 2.23482453 |
| 50 | Peripheral primitive neuroectodermal neoplasm (HP:0030067) | 2.23482453 |
| 51 | Neuroblastoma (HP:0003006) | 2.23482453 |
| 52 | Primitive neuroectodermal tumor (HP:0030065) | 2.23482453 |
| 53 | Psychosis (HP:0000709) | 2.21412701 |
| 54 | Intestinal polyp (HP:0005266) | 2.17362800 |
| 55 | Aplasia/Hypoplasia of metatarsal bones (HP:0001964) | 2.15018507 |
| 56 | Alkalosis (HP:0001948) | 2.14470140 |
| 57 | Hypotension (HP:0002615) | 2.08088366 |
| 58 | Poor suck (HP:0002033) | 2.05112560 |
| 59 | Orthostatic hypotension (HP:0001278) | 2.04492200 |
| 60 | Malnutrition (HP:0004395) | 10.6536012 |
| 61 | Bone pain (HP:0002653) | 1.98107111 |
| 62 | Precocious puberty (HP:0000826) | 1.95935584 |
| 63 | Hypocalcemia (HP:0002901) | 1.86796958 |
| 64 | Hypoplasia of dental enamel (HP:0006297) | 1.86734581 |
| 65 | Neoplasm of the thyroid gland (HP:0100031) | 1.82655393 |
| 66 | Hypokinesia (HP:0002375) | 1.81330657 |
| 67 | Spastic diplegia (HP:0001264) | 1.79735924 |
| 68 | Neonatal hypoglycemia (HP:0001998) | 1.78181481 |
| 69 | Conjugated hyperbilirubinemia (HP:0002908) | 1.76440991 |
| 70 | Left ventricular hypertrophy (HP:0001712) | 1.76229115 |
| 71 | Exercise-induced myalgia (HP:0003738) | 1.75268495 |
| 72 | Abnormality of the basal ganglia (HP:0002134) | 1.74959418 |
| 73 | Global brain atrophy (HP:0002283) | 1.72047731 |
| 74 | Abnormality of renin-angiotensin system (HP:0000847) | 1.71331473 |
| 75 | Methylmalonic acidemia (HP:0002912) | 1.70890430 |
| 76 | Generalized tonic-clonic seizures (HP:0002069) | 1.67902017 |
| 77 | Osteoarthritis (HP:0002758) | 1.67552630 |
| 78 | Episodic fever (HP:0001954) | 1.66116471 |
| 79 | Renal salt wasting (HP:0000127) | 1.61259694 |
| 80 | Abnormality of homocysteine metabolism (HP:0010919) | 1.60829277 |
| 81 | Homocystinuria (HP:0002156) | 1.60829277 |
| 82 | Supranuclear gaze palsy (HP:0000605) | 1.55844398 |
| 83 | Skin rash (HP:0000988) | 1.55452495 |
| 84 | Retinal dysplasia (HP:0007973) | 1.54965667 |
| 85 | Asthma (HP:0002099) | 1.53335560 |
| 86 | Abnormality of chloride homeostasis (HP:0011422) | 1.51804366 |
| 87 | Hyperventilation (HP:0002883) | 1.50256458 |
| 88 | Abnormal autonomic nervous system physiology (HP:0012332) | 1.46847711 |
| 89 | Abnormal pupillary function (HP:0007686) | 1.46152912 |
| 90 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 1.40938778 |
| 91 | Abnormal gallbladder physiology (HP:0012438) | 1.39187196 |
| 92 | Cholecystitis (HP:0001082) | 1.39187196 |
| 93 | Fragile skin (HP:0001030) | 1.38971557 |
| 94 | Round face (HP:0000311) | 1.38782200 |
| 95 | Hyperkalemia (HP:0002153) | 1.38369032 |
| 96 | Methylmalonic aciduria (HP:0012120) | 1.37942428 |
| 97 | Torticollis (HP:0000473) | 1.37108502 |
| 98 | Hyperaldosteronism (HP:0000859) | 1.36757178 |
| 99 | Metabolic alkalosis (HP:0200114) | 1.35992914 |
| 100 | Limb-girdle muscle atrophy (HP:0003797) | 1.32275978 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BMPR1B | 4.46344652 |
| 2 | NTRK3 | 3.75839636 |
| 3 | BUB1 | 3.67929077 |
| 4 | CSNK1G3 | 3.22769340 |
| 5 | CSNK1G2 | 2.99598613 |
| 6 | DYRK3 | 2.76736828 |
| 7 | TGFBR1 | 2.75310285 |
| 8 | NTRK1 | 2.58222013 |
| 9 | CSNK1G1 | 2.56424977 |
| 10 | MAPKAPK5 | 2.44351254 |
| 11 | PDGFRA | 2.43689411 |
| 12 | CDK8 | 2.36426530 |
| 13 | TRIB3 | 2.07888980 |
| 14 | UHMK1 | 2.01719098 |
| 15 | SGK223 | 1.98180344 |
| 16 | SGK494 | 1.98180344 |
| 17 | NLK | 1.94104734 |
| 18 | EPHB2 | 1.80831761 |
| 19 | PHKG2 | 1.79700493 |
| 20 | PHKG1 | 1.79700493 |
| 21 | GRK7 | 1.75564165 |
| 22 | CSNK1A1L | 1.73511039 |
| 23 | DDR2 | 1.69740867 |
| 24 | PAK6 | 1.68701601 |
| 25 | LMTK2 | 1.66520414 |
| 26 | DAPK2 | 1.65204061 |
| 27 | TESK1 | 1.59651834 |
| 28 | GRK1 | 1.59566706 |
| 29 | IRAK2 | 1.42979936 |
| 30 | PAK3 | 1.31181362 |
| 31 | PDPK1 | 1.29148288 |
| 32 | PLK2 | 1.23601207 |
| 33 | PRKCG | 1.19057872 |
| 34 | RIPK4 | 1.13707204 |
| 35 | MINK1 | 1.13241746 |
| 36 | MATK | 1.10701391 |
| 37 | PRPF4B | 1.05325243 |
| 38 | EPHA4 | 1.00372380 |
| 39 | LIMK1 | 0.99182996 |
| 40 | ADRBK1 | 0.93001447 |
| 41 | MAP3K2 | 0.92635601 |
| 42 | GRK5 | 0.91852230 |
| 43 | CAMK2G | 0.89119756 |
| 44 | MAP2K1 | 0.86252517 |
| 45 | WNK4 | 0.83119372 |
| 46 | MAP3K4 | 0.77693173 |
| 47 | PDGFRB | 0.76868701 |
| 48 | FER | 0.76650967 |
| 49 | CDK15 | 0.76632359 |
| 50 | MAP3K3 | 0.76563717 |
| 51 | MET | 0.75571832 |
| 52 | CDK18 | 0.75553299 |
| 53 | KSR2 | 0.73172331 |
| 54 | TYRO3 | 0.71884650 |
| 55 | OXSR1 | 0.71195584 |
| 56 | GSK3A | 0.69859958 |
| 57 | HIPK2 | 0.68118008 |
| 58 | NTRK2 | 0.68069662 |
| 59 | CDK14 | 0.66093493 |
| 60 | CDK11A | 0.64668946 |
| 61 | PRKD1 | 0.64241104 |
| 62 | ILK | 0.62446071 |
| 63 | PRKCQ | 0.60023041 |
| 64 | PRKCZ | 0.58274217 |
| 65 | SGK3 | 0.57604525 |
| 66 | PTK2B | 0.56248187 |
| 67 | CDK5 | 0.54845585 |
| 68 | IRAK1 | 0.54279750 |
| 69 | DYRK2 | 0.51872674 |
| 70 | MAPK4 | 0.51718405 |
| 71 | PRKG2 | 0.51124827 |
| 72 | CAMK2B | 0.50574727 |
| 73 | LATS2 | 0.48748828 |
| 74 | ALK | 0.48561100 |
| 75 | ERN1 | 0.47909923 |
| 76 | FES | 0.47795654 |
| 77 | RPS6KA4 | 0.45599013 |
| 78 | AKT3 | 0.44102015 |
| 79 | CAMK2A | 0.44078816 |
| 80 | RPS6KA5 | 0.42573197 |
| 81 | CSNK1A1 | 0.40730458 |
| 82 | PRKCE | 0.38839709 |
| 83 | PRKACA | 0.38561926 |
| 84 | CAMK2D | 0.36343961 |
| 85 | ERBB3 | 0.34684705 |
| 86 | MARK1 | 0.33609891 |
| 87 | MST1R | 0.33574066 |
| 88 | CSNK1E | 0.33486016 |
| 89 | PAK1 | 0.32971821 |
| 90 | STK39 | 0.31836319 |
| 91 | PRKCB | 0.31357774 |
| 92 | PRKCD | 0.29910674 |
| 93 | EPHB1 | 0.29403666 |
| 94 | PTK6 | 0.27614727 |
| 95 | FLT3 | 0.27195648 |
| 96 | IGF1R | 0.26732532 |
| 97 | CAMK1 | 0.26715770 |
| 98 | SGK2 | 0.25990718 |
| 99 | FYN | 0.24810073 |
| 100 | MAP2K2 | 0.24476046 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Cocaine addiction_Homo sapiens_hsa05030 | 3.21236177 |
| 2 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 3.12795760 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.01852943 |
| 4 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.87586043 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 2.71208474 |
| 6 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 2.66252202 |
| 7 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.60026205 |
| 8 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 2.46899044 |
| 9 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.25187078 |
| 10 | Renin secretion_Homo sapiens_hsa04924 | 2.24266431 |
| 11 | Bile secretion_Homo sapiens_hsa04976 | 2.16785710 |
| 12 | Alzheimers disease_Homo sapiens_hsa05010 | 2.04206136 |
| 13 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.87669981 |
| 14 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 1.86693688 |
| 15 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.82242795 |
| 16 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.80460481 |
| 17 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.77614260 |
| 18 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.75263521 |
| 19 | Long-term depression_Homo sapiens_hsa04730 | 1.73932593 |
| 20 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.73868167 |
| 21 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 1.71690741 |
| 22 | Circadian entrainment_Homo sapiens_hsa04713 | 1.69163786 |
| 23 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.67434007 |
| 24 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.55099186 |
| 25 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.52931093 |
| 26 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 1.52672454 |
| 27 | Salivary secretion_Homo sapiens_hsa04970 | 1.46211720 |
| 28 | Insulin secretion_Homo sapiens_hsa04911 | 1.43239019 |
| 29 | Huntingtons disease_Homo sapiens_hsa05016 | 1.41144080 |
| 30 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.41022280 |
| 31 | Morphine addiction_Homo sapiens_hsa05032 | 1.40160033 |
| 32 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.38696384 |
| 33 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 1.36738974 |
| 34 | Sulfur relay system_Homo sapiens_hsa04122 | 1.35701276 |
| 35 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 1.33494796 |
| 36 | Gap junction_Homo sapiens_hsa04540 | 1.31992809 |
| 37 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.29320914 |
| 38 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.26439207 |
| 39 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.26322752 |
| 40 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.21616499 |
| 41 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.14218639 |
| 42 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.13948489 |
| 43 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.09769134 |
| 44 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.07311453 |
| 45 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.06845687 |
| 46 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.03670218 |
| 47 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.00828760 |
| 48 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.00041429 |
| 49 | Melanogenesis_Homo sapiens_hsa04916 | 0.97931527 |
| 50 | Alcoholism_Homo sapiens_hsa05034 | 0.94416070 |
| 51 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.94190527 |
| 52 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.93754786 |
| 53 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.93661978 |
| 54 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.91873052 |
| 55 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.84352662 |
| 56 | Amoebiasis_Homo sapiens_hsa05146 | 0.81780189 |
| 57 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.81460215 |
| 58 | Histidine metabolism_Homo sapiens_hsa00340 | 0.81429385 |
| 59 | GABAergic synapse_Homo sapiens_hsa04727 | 0.78698017 |
| 60 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.71799533 |
| 61 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.68897380 |
| 62 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.65145017 |
| 63 | Platelet activation_Homo sapiens_hsa04611 | 0.59297341 |
| 64 | Taste transduction_Homo sapiens_hsa04742 | 0.58837605 |
| 65 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.58009417 |
| 66 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.57302306 |
| 67 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.57227592 |
| 68 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.56648820 |
| 69 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.55632934 |
| 70 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.55582409 |
| 71 | Phagosome_Homo sapiens_hsa04145 | 0.53917382 |
| 72 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.53188640 |
| 73 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.50524897 |
| 74 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.48920768 |
| 75 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.48809022 |
| 76 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.46144763 |
| 77 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.44902911 |
| 78 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.42957626 |
| 79 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.40011325 |
| 80 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.39787153 |
| 81 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.38065303 |
| 82 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.37792289 |
| 83 | Long-term potentiation_Homo sapiens_hsa04720 | 0.37392191 |
| 84 | Prion diseases_Homo sapiens_hsa05020 | 0.36420442 |
| 85 | Lysosome_Homo sapiens_hsa04142 | 0.35587968 |
| 86 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.34413573 |
| 87 | Thyroid cancer_Homo sapiens_hsa05216 | 0.30784802 |
| 88 | Olfactory transduction_Homo sapiens_hsa04740 | 0.29715069 |
| 89 | Peroxisome_Homo sapiens_hsa04146 | 0.27255302 |
| 90 | Metabolic pathways_Homo sapiens_hsa01100 | 0.24533727 |
| 91 | Nicotine addiction_Homo sapiens_hsa05033 | 0.23908662 |
| 92 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.23724261 |
| 93 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.23703967 |
| 94 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.22421006 |
| 95 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.20666858 |
| 96 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.19694397 |
| 97 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.18749379 |
| 98 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.18447945 |
| 99 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.17320651 |
| 100 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.17165120 |

