

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 7.42452972 |
| 2 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 6.35129594 |
| 3 | ATP synthesis coupled proton transport (GO:0015986) | 6.35129594 |
| 4 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 5.65017988 |
| 5 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.45608571 |
| 6 | chaperone-mediated protein transport (GO:0072321) | 5.38842297 |
| 7 | respiratory electron transport chain (GO:0022904) | 5.30095839 |
| 8 | electron transport chain (GO:0022900) | 5.19532828 |
| 9 | proteasome assembly (GO:0043248) | 4.95663131 |
| 10 | protein complex biogenesis (GO:0070271) | 4.93944933 |
| 11 | protein neddylation (GO:0045116) | 4.85981809 |
| 12 | viral transcription (GO:0019083) | 4.82748213 |
| 13 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.79281800 |
| 14 | ribosomal small subunit assembly (GO:0000028) | 4.77266802 |
| 15 | translational termination (GO:0006415) | 4.77015747 |
| 16 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.74013487 |
| 17 | NADH dehydrogenase complex assembly (GO:0010257) | 4.74013487 |
| 18 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.74013487 |
| 19 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.54868682 |
| 20 | cotranslational protein targeting to membrane (GO:0006613) | 4.53063691 |
| 21 | protein targeting to ER (GO:0045047) | 4.44890427 |
| 22 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.28434849 |
| 23 | protein localization to endoplasmic reticulum (GO:0070972) | 4.21973653 |
| 24 | termination of RNA polymerase III transcription (GO:0006386) | 4.21189808 |
| 25 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 4.21189808 |
| 26 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.15166828 |
| 27 | ribosomal large subunit biogenesis (GO:0042273) | 4.06702656 |
| 28 | translational elongation (GO:0006414) | 4.04290025 |
| 29 | respiratory chain complex IV assembly (GO:0008535) | 4.03410587 |
| 30 | regulation of mitochondrial translation (GO:0070129) | 3.95174816 |
| 31 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.94151952 |
| 32 | ribosomal small subunit biogenesis (GO:0042274) | 3.88197518 |
| 33 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.87910123 |
| 34 | translation (GO:0006412) | 3.85681998 |
| 35 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.80527951 |
| 36 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.80405803 |
| 37 | maturation of SSU-rRNA (GO:0030490) | 3.78688947 |
| 38 | translational initiation (GO:0006413) | 3.76953088 |
| 39 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.75348320 |
| 40 | negative regulation of ligase activity (GO:0051352) | 3.75348320 |
| 41 | cullin deneddylation (GO:0010388) | 3.75178993 |
| 42 | chromatin remodeling at centromere (GO:0031055) | 3.71020075 |
| 43 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.70968837 |
| 44 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.70968837 |
| 45 | cytochrome complex assembly (GO:0017004) | 3.69438840 |
| 46 | cellular protein complex disassembly (GO:0043624) | 3.67131850 |
| 47 | CENP-A containing nucleosome assembly (GO:0034080) | 3.66547840 |
| 48 | establishment of integrated proviral latency (GO:0075713) | 3.65663250 |
| 49 | viral life cycle (GO:0019058) | 3.64991622 |
| 50 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.59030479 |
| 51 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.56116078 |
| 52 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.55508375 |
| 53 | protein-cofactor linkage (GO:0018065) | 3.54702471 |
| 54 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.50378864 |
| 55 | protein targeting to mitochondrion (GO:0006626) | 3.49913361 |
| 56 | ATP biosynthetic process (GO:0006754) | 3.47193569 |
| 57 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.44753908 |
| 58 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.44753908 |
| 59 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.44753908 |
| 60 | hydrogen ion transmembrane transport (GO:1902600) | 3.43214510 |
| 61 | rRNA modification (GO:0000154) | 3.42662938 |
| 62 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.41257549 |
| 63 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.41257549 |
| 64 | protein deneddylation (GO:0000338) | 3.40418855 |
| 65 | sequestering of actin monomers (GO:0042989) | 3.37424344 |
| 66 | DNA damage response, detection of DNA damage (GO:0042769) | 3.36549916 |
| 67 | spliceosomal snRNP assembly (GO:0000387) | 3.35887422 |
| 68 | inner mitochondrial membrane organization (GO:0007007) | 3.35720789 |
| 69 | protein localization to mitochondrion (GO:0070585) | 3.34218815 |
| 70 | establishment of protein localization to mitochondrion (GO:0072655) | 3.33788436 |
| 71 | oxidative phosphorylation (GO:0006119) | 3.31977624 |
| 72 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.31062589 |
| 73 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.29812949 |
| 74 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.29812949 |
| 75 | cellular component biogenesis (GO:0044085) | 3.28588565 |
| 76 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.28417682 |
| 77 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.27726197 |
| 78 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.22337334 |
| 79 | platelet dense granule organization (GO:0060155) | 3.17374375 |
| 80 | intracellular protein transmembrane import (GO:0044743) | 3.13381749 |
| 81 | proton transport (GO:0015992) | 3.09542533 |
| 82 | protein complex disassembly (GO:0043241) | 3.09035614 |
| 83 | positive regulation of ligase activity (GO:0051351) | 3.05117089 |
| 84 | establishment of viral latency (GO:0019043) | 3.03677717 |
| 85 | hydrogen transport (GO:0006818) | 3.03229915 |
| 86 | macromolecular complex disassembly (GO:0032984) | 3.02581559 |
| 87 | histone exchange (GO:0043486) | 3.00616962 |
| 88 | kinetochore assembly (GO:0051382) | 3.00030921 |
| 89 | DNA double-strand break processing (GO:0000729) | 2.98504571 |
| 90 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.96075417 |
| 91 | pseudouridine synthesis (GO:0001522) | 2.95339315 |
| 92 | protein targeting to membrane (GO:0006612) | 2.93729120 |
| 93 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.93420892 |
| 94 | mitochondrial transport (GO:0006839) | 2.93003227 |
| 95 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.92257415 |
| 96 | peptidyl-histidine modification (GO:0018202) | 2.91982498 |
| 97 | DNA replication checkpoint (GO:0000076) | 2.91254877 |
| 98 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.90734581 |
| 99 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.90734581 |
| 100 | purine nucleobase biosynthetic process (GO:0009113) | 2.90334287 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.14188723 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.81524874 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.53946450 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.11522020 |
| 5 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.38654378 |
| 6 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.32514533 |
| 7 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.27732880 |
| 8 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.20202159 |
| 9 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.14189465 |
| 10 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 3.06541805 |
| 11 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.94207467 |
| 12 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.69734584 |
| 13 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.69174994 |
| 14 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.62666780 |
| 15 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.62032916 |
| 16 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.47547352 |
| 17 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.34971662 |
| 18 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.30911551 |
| 19 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.27114106 |
| 20 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.14640539 |
| 21 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.12464371 |
| 22 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.11463664 |
| 23 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.05028722 |
| 24 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.03627647 |
| 25 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.98750572 |
| 26 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.94081237 |
| 27 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.92581628 |
| 28 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.90844430 |
| 29 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.89357785 |
| 30 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.87867182 |
| 31 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.86143527 |
| 32 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.81611029 |
| 33 | EWS_26573619_Chip-Seq_HEK293_Human | 1.80921150 |
| 34 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.79555588 |
| 35 | VDR_22108803_ChIP-Seq_LS180_Human | 1.78502556 |
| 36 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.77692619 |
| 37 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.73866690 |
| 38 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.73353905 |
| 39 | FUS_26573619_Chip-Seq_HEK293_Human | 1.72845151 |
| 40 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.72201904 |
| 41 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.70135601 |
| 42 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.62954286 |
| 43 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.61492904 |
| 44 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.56464314 |
| 45 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.55243652 |
| 46 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.54951413 |
| 47 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.52266006 |
| 48 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.48319660 |
| 49 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.44231881 |
| 50 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.34236225 |
| 51 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.32056488 |
| 52 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.31070175 |
| 53 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.29358255 |
| 54 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.28930873 |
| 55 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.27920369 |
| 56 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.26137870 |
| 57 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.25764115 |
| 58 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.25424339 |
| 59 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.24446258 |
| 60 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.18478373 |
| 61 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.18323842 |
| 62 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.17509974 |
| 63 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.14298674 |
| 64 | P300_19829295_ChIP-Seq_ESCs_Human | 1.14165779 |
| 65 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.13216245 |
| 66 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.12278969 |
| 67 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.11999240 |
| 68 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.07105904 |
| 69 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.06979388 |
| 70 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.06358844 |
| 71 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.05742528 |
| 72 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.04176680 |
| 73 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.03789099 |
| 74 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.03305935 |
| 75 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.01460584 |
| 76 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.00397872 |
| 77 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.99512718 |
| 78 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.98677969 |
| 79 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.91399298 |
| 80 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.91149095 |
| 81 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.90411658 |
| 82 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.88442485 |
| 83 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.87762131 |
| 84 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.85439272 |
| 85 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.84414894 |
| 86 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.83643581 |
| 87 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.83643581 |
| 88 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.83186255 |
| 89 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.81302651 |
| 90 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 0.80082484 |
| 91 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.76285264 |
| 92 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.75527003 |
| 93 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.75527003 |
| 94 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.73903427 |
| 95 | AR_20517297_ChIP-Seq_VCAP_Human | 0.73843644 |
| 96 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 0.73359843 |
| 97 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.72934337 |
| 98 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.72680312 |
| 99 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.72452664 |
| 100 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.72320092 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 3.43257904 |
| 2 | MP0006292_abnormal_olfactory_placode | 3.21941550 |
| 3 | MP0008058_abnormal_DNA_repair | 3.09400181 |
| 4 | MP0001529_abnormal_vocalization | 2.69591808 |
| 5 | MP0006072_abnormal_retinal_apoptosis | 2.56114075 |
| 6 | MP0003806_abnormal_nucleotide_metabolis | 2.38044709 |
| 7 | MP0002102_abnormal_ear_morphology | 2.35350500 |
| 8 | MP0002938_white_spotting | 2.32140801 |
| 9 | MP0003186_abnormal_redox_activity | 2.23403158 |
| 10 | MP0008877_abnormal_DNA_methylation | 2.20548513 |
| 11 | MP0003693_abnormal_embryo_hatching | 2.18030098 |
| 12 | MP0003880_abnormal_central_pattern | 2.16312756 |
| 13 | MP0010094_abnormal_chromosome_stability | 2.15416547 |
| 14 | MP0004957_abnormal_blastocyst_morpholog | 2.14088931 |
| 15 | MP0003136_yellow_coat_color | 2.13914266 |
| 16 | MP0003011_delayed_dark_adaptation | 2.06041274 |
| 17 | MP0006036_abnormal_mitochondrial_physio | 2.04785716 |
| 18 | MP0003718_maternal_effect | 2.03362088 |
| 19 | MP0009697_abnormal_copulation | 2.01482879 |
| 20 | MP0002638_abnormal_pupillary_reflex | 1.90518741 |
| 21 | MP0001293_anophthalmia | 1.89511273 |
| 22 | MP0000372_irregular_coat_pigmentation | 1.86427826 |
| 23 | MP0002736_abnormal_nociception_after | 1.85179229 |
| 24 | MP0004142_abnormal_muscle_tone | 1.83797108 |
| 25 | MP0005084_abnormal_gallbladder_morpholo | 1.75453273 |
| 26 | MP0006035_abnormal_mitochondrial_morpho | 1.73746333 |
| 27 | MP0008789_abnormal_olfactory_epithelium | 1.65807046 |
| 28 | MP0003077_abnormal_cell_cycle | 1.64258457 |
| 29 | MP0006276_abnormal_autonomic_nervous | 1.60026486 |
| 30 | MP0005253_abnormal_eye_physiology | 1.57845172 |
| 31 | MP0002837_dystrophic_cardiac_calcinosis | 1.56345221 |
| 32 | MP0008932_abnormal_embryonic_tissue | 1.56204970 |
| 33 | MP0003121_genomic_imprinting | 1.54865608 |
| 34 | MP0004133_heterotaxia | 1.52246568 |
| 35 | MP0001984_abnormal_olfaction | 1.49345623 |
| 36 | MP0010030_abnormal_orbit_morphology | 1.48813649 |
| 37 | MP0003786_premature_aging | 1.47661328 |
| 38 | MP0002234_abnormal_pharynx_morphology | 1.45836412 |
| 39 | MP0003941_abnormal_skin_development | 1.45199471 |
| 40 | MP0003111_abnormal_nucleus_morphology | 1.40605112 |
| 41 | MP0005551_abnormal_eye_electrophysiolog | 1.39453947 |
| 42 | MP0008995_early_reproductive_senescence | 1.33219093 |
| 43 | MP0002277_abnormal_respiratory_mucosa | 1.32428843 |
| 44 | MP0002163_abnormal_gland_morphology | 1.31726180 |
| 45 | MP0003787_abnormal_imprinting | 1.25114263 |
| 46 | MP0003567_abnormal_fetal_cardiomyocyte | 1.23446759 |
| 47 | MP0003890_abnormal_embryonic-extraembry | 1.23013549 |
| 48 | MP0001968_abnormal_touch/_nociception | 1.23013415 |
| 49 | MP0000631_abnormal_neuroendocrine_gland | 1.20424785 |
| 50 | MP0001764_abnormal_homeostasis | 1.19799314 |
| 51 | MP0008007_abnormal_cellular_replicative | 1.19767494 |
| 52 | MP0001905_abnormal_dopamine_level | 1.19314508 |
| 53 | MP0009046_muscle_twitch | 1.17615756 |
| 54 | MP0000049_abnormal_middle_ear | 1.15298243 |
| 55 | MP0002653_abnormal_ependyma_morphology | 1.14839174 |
| 56 | MP0005394_taste/olfaction_phenotype | 1.13679304 |
| 57 | MP0005499_abnormal_olfactory_system | 1.13679304 |
| 58 | MP0004147_increased_porphyrin_level | 1.13131976 |
| 59 | MP0010386_abnormal_urinary_bladder | 1.11873189 |
| 60 | MP0002160_abnormal_reproductive_system | 1.10382933 |
| 61 | MP0001485_abnormal_pinna_reflex | 1.07906163 |
| 62 | MP0002751_abnormal_autonomic_nervous | 1.07325172 |
| 63 | MP0003937_abnormal_limbs/digits/tail_de | 1.06998012 |
| 64 | MP0003123_paternal_imprinting | 1.06398556 |
| 65 | MP0008872_abnormal_physiological_respon | 1.05812295 |
| 66 | MP0003315_abnormal_perineum_morphology | 1.05425781 |
| 67 | MP0004215_abnormal_myocardial_fiber | 1.05424332 |
| 68 | MP0003122_maternal_imprinting | 1.04888367 |
| 69 | MP0002272_abnormal_nervous_system | 1.03784362 |
| 70 | MP0002233_abnormal_nose_morphology | 1.03153619 |
| 71 | MP0003195_calcinosis | 1.02665949 |
| 72 | MP0002210_abnormal_sex_determination | 1.00779396 |
| 73 | MP0009745_abnormal_behavioral_response | 0.97900687 |
| 74 | MP0001286_abnormal_eye_development | 0.97412694 |
| 75 | MP0002282_abnormal_trachea_morphology | 0.95337117 |
| 76 | MP0003119_abnormal_digestive_system | 0.94935122 |
| 77 | MP0005389_reproductive_system_phenotype | 0.94699930 |
| 78 | MP0001188_hyperpigmentation | 0.93811151 |
| 79 | MP0003938_abnormal_ear_development | 0.92349123 |
| 80 | MP0005391_vision/eye_phenotype | 0.92149447 |
| 81 | MP0005379_endocrine/exocrine_gland_phen | 0.89214288 |
| 82 | MP0002095_abnormal_skin_pigmentation | 0.89107922 |
| 83 | MP0001145_abnormal_male_reproductive | 0.83463320 |
| 84 | MP0000653_abnormal_sex_gland | 0.82939773 |
| 85 | MP0001929_abnormal_gametogenesis | 0.82935565 |
| 86 | MP0005195_abnormal_posterior_eye | 0.81902575 |
| 87 | MP0004145_abnormal_muscle_electrophysio | 0.81716809 |
| 88 | MP0004742_abnormal_vestibular_system | 0.80232375 |
| 89 | MP0001486_abnormal_startle_reflex | 0.79993288 |
| 90 | MP0002822_catalepsy | 0.79846291 |
| 91 | MP0003283_abnormal_digestive_organ | 0.79803991 |
| 92 | MP0002752_abnormal_somatic_nervous | 0.79312831 |
| 93 | MP0005645_abnormal_hypothalamus_physiol | 0.78878620 |
| 94 | MP0000778_abnormal_nervous_system | 0.78799206 |
| 95 | MP0003646_muscle_fatigue | 0.78487754 |
| 96 | MP0005646_abnormal_pituitary_gland | 0.73066474 |
| 97 | MP0000026_abnormal_inner_ear | 0.72967926 |
| 98 | MP0000647_abnormal_sebaceous_gland | 0.72792215 |
| 99 | MP0000358_abnormal_cell_content/ | 0.72681696 |
| 100 | MP0003137_abnormal_impulse_conducting | 0.71073329 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 5.67897272 |
| 2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 5.13574488 |
| 3 | Mitochondrial inheritance (HP:0001427) | 5.12870980 |
| 4 | Acute encephalopathy (HP:0006846) | 4.91023411 |
| 5 | Increased hepatocellular lipid droplets (HP:0006565) | 4.74759633 |
| 6 | Progressive macrocephaly (HP:0004481) | 4.74632216 |
| 7 | Increased CSF lactate (HP:0002490) | 4.62819709 |
| 8 | Hepatocellular necrosis (HP:0001404) | 4.47083278 |
| 9 | Lipid accumulation in hepatocytes (HP:0006561) | 4.28801270 |
| 10 | Hepatic necrosis (HP:0002605) | 4.08245896 |
| 11 | Renal Fanconi syndrome (HP:0001994) | 3.86998745 |
| 12 | Cerebral edema (HP:0002181) | 3.70861088 |
| 13 | Abnormal number of erythroid precursors (HP:0012131) | 3.51721547 |
| 14 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.46740640 |
| 15 | 3-Methylglutaconic aciduria (HP:0003535) | 3.46190411 |
| 16 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.43850275 |
| 17 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.43850275 |
| 18 | Increased intramyocellular lipid droplets (HP:0012240) | 3.28791242 |
| 19 | Macrocytic anemia (HP:0001972) | 3.17268408 |
| 20 | Reticulocytopenia (HP:0001896) | 3.06664933 |
| 21 | Exertional dyspnea (HP:0002875) | 3.04142778 |
| 22 | Lactic acidosis (HP:0003128) | 3.03333032 |
| 23 | Increased serum lactate (HP:0002151) | 3.01100057 |
| 24 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.96173102 |
| 25 | Colon cancer (HP:0003003) | 2.84136117 |
| 26 | Respiratory failure (HP:0002878) | 2.84129392 |
| 27 | Optic disc pallor (HP:0000543) | 2.75308139 |
| 28 | Congenital, generalized hypertrichosis (HP:0004540) | 2.74990842 |
| 29 | Leukodystrophy (HP:0002415) | 2.74435624 |
| 30 | Exercise intolerance (HP:0003546) | 2.73578675 |
| 31 | Methylmalonic acidemia (HP:0002912) | 2.72680358 |
| 32 | Pancreatic cysts (HP:0001737) | 2.69601535 |
| 33 | Increased muscle lipid content (HP:0009058) | 2.63319549 |
| 34 | Abnormality of the labia minora (HP:0012880) | 2.60419788 |
| 35 | Pancreatic fibrosis (HP:0100732) | 2.55084220 |
| 36 | Respiratory difficulties (HP:0002880) | 2.53384105 |
| 37 | Type I transferrin isoform profile (HP:0003642) | 2.53365567 |
| 38 | Molar tooth sign on MRI (HP:0002419) | 2.52554659 |
| 39 | Abnormality of midbrain morphology (HP:0002418) | 2.52554659 |
| 40 | Aplastic anemia (HP:0001915) | 2.52496971 |
| 41 | Medial flaring of the eyebrow (HP:0010747) | 2.49017436 |
| 42 | Abnormality of renal resorption (HP:0011038) | 2.46051217 |
| 43 | True hermaphroditism (HP:0010459) | 2.40907209 |
| 44 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.34009786 |
| 45 | Methylmalonic aciduria (HP:0012120) | 2.29755063 |
| 46 | Septo-optic dysplasia (HP:0100842) | 2.29369204 |
| 47 | Lethargy (HP:0001254) | 2.24344524 |
| 48 | Nephronophthisis (HP:0000090) | 2.18096612 |
| 49 | Abnormality of alanine metabolism (HP:0010916) | 2.18038226 |
| 50 | Hyperalaninemia (HP:0003348) | 2.18038226 |
| 51 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.18038226 |
| 52 | CNS demyelination (HP:0007305) | 2.17298602 |
| 53 | Increased serum pyruvate (HP:0003542) | 2.16992007 |
| 54 | Pallor (HP:0000980) | 2.16253594 |
| 55 | Hyperglycinemia (HP:0002154) | 2.08915768 |
| 56 | Glycosuria (HP:0003076) | 2.03634667 |
| 57 | Abnormality of urine glucose concentration (HP:0011016) | 2.03634667 |
| 58 | Abnormality of serum amino acid levels (HP:0003112) | 2.03449566 |
| 59 | X-linked dominant inheritance (HP:0001423) | 2.03278748 |
| 60 | Stenosis of the external auditory canal (HP:0000402) | 1.99790843 |
| 61 | Oral leukoplakia (HP:0002745) | 1.99495366 |
| 62 | Congenital primary aphakia (HP:0007707) | 1.98797271 |
| 63 | Meckel diverticulum (HP:0002245) | 1.98593391 |
| 64 | Abnormality of methionine metabolism (HP:0010901) | 1.96776734 |
| 65 | Gait imbalance (HP:0002141) | 1.95285295 |
| 66 | Generalized aminoaciduria (HP:0002909) | 1.94665269 |
| 67 | Abnormality of the ileum (HP:0001549) | 1.92441791 |
| 68 | Sclerocornea (HP:0000647) | 1.92005030 |
| 69 | Abnormality of the anterior horn cell (HP:0006802) | 1.91539442 |
| 70 | Degeneration of anterior horn cells (HP:0002398) | 1.91539442 |
| 71 | Abnormal protein glycosylation (HP:0012346) | 1.90854281 |
| 72 | Abnormal glycosylation (HP:0012345) | 1.90854281 |
| 73 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.90854281 |
| 74 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.90854281 |
| 75 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.89786203 |
| 76 | Nephrogenic diabetes insipidus (HP:0009806) | 1.88706574 |
| 77 | Hyperphosphaturia (HP:0003109) | 1.87779177 |
| 78 | Abnormal lung lobation (HP:0002101) | 1.84396704 |
| 79 | Triphalangeal thumb (HP:0001199) | 1.81454193 |
| 80 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.81406486 |
| 81 | Reduced antithrombin III activity (HP:0001976) | 1.78502585 |
| 82 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.77299734 |
| 83 | Abnormality of the renal medulla (HP:0100957) | 1.76925865 |
| 84 | Hypothermia (HP:0002045) | 1.76461537 |
| 85 | Microvesicular hepatic steatosis (HP:0001414) | 1.76455776 |
| 86 | Abnormality of glycolysis (HP:0004366) | 1.76038811 |
| 87 | Absent septum pellucidum (HP:0001331) | 1.73312478 |
| 88 | Genital tract atresia (HP:0001827) | 1.73046122 |
| 89 | Myokymia (HP:0002411) | 1.72578692 |
| 90 | Amniotic constriction ring (HP:0009775) | 1.70416739 |
| 91 | Abnormality of placental membranes (HP:0011409) | 1.70416739 |
| 92 | Vaginal atresia (HP:0000148) | 1.70299178 |
| 93 | Volvulus (HP:0002580) | 1.69621638 |
| 94 | Poor suck (HP:0002033) | 1.69364170 |
| 95 | Supernumerary spleens (HP:0009799) | 1.69125686 |
| 96 | Emotional lability (HP:0000712) | 1.69124945 |
| 97 | Pancytopenia (HP:0001876) | 1.67744801 |
| 98 | Bilateral microphthalmos (HP:0007633) | 1.64468403 |
| 99 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.64408701 |
| 100 | Anencephaly (HP:0002323) | 1.63169474 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 4.21119372 |
| 2 | STK16 | 3.63117002 |
| 3 | BUB1 | 3.17735350 |
| 4 | ZAK | 2.77158544 |
| 5 | SRPK1 | 2.63795137 |
| 6 | VRK1 | 2.60577824 |
| 7 | MAP4K2 | 2.54784910 |
| 8 | MAP3K12 | 2.46916622 |
| 9 | CDC7 | 2.43789444 |
| 10 | MST4 | 2.31217362 |
| 11 | PBK | 2.21785474 |
| 12 | NME1 | 2.16598367 |
| 13 | NUAK1 | 2.08257781 |
| 14 | WNK3 | 1.99959630 |
| 15 | PLK4 | 1.89462810 |
| 16 | BMPR1B | 1.71401290 |
| 17 | PLK3 | 1.69762154 |
| 18 | NEK1 | 1.69684811 |
| 19 | DYRK2 | 1.68539501 |
| 20 | EIF2AK3 | 1.61057979 |
| 21 | BCKDK | 1.53996696 |
| 22 | TNIK | 1.51322903 |
| 23 | TRIM28 | 1.49603237 |
| 24 | TLK1 | 1.49463716 |
| 25 | EIF2AK1 | 1.41032665 |
| 26 | TAF1 | 1.39013669 |
| 27 | MKNK1 | 1.31863906 |
| 28 | ADRBK2 | 1.26488684 |
| 29 | CDK19 | 1.23529449 |
| 30 | TTK | 1.21990723 |
| 31 | WEE1 | 1.18755822 |
| 32 | GRK1 | 1.17969647 |
| 33 | MKNK2 | 1.14644452 |
| 34 | PDK2 | 1.13594099 |
| 35 | TSSK6 | 1.13546574 |
| 36 | MAP2K7 | 1.12332603 |
| 37 | MAP3K4 | 1.10043031 |
| 38 | INSRR | 1.09710039 |
| 39 | PLK1 | 1.09411805 |
| 40 | NME2 | 1.08080271 |
| 41 | CSNK1G3 | 1.00515923 |
| 42 | LIMK1 | 0.99957176 |
| 43 | CSNK1G1 | 0.97042383 |
| 44 | DYRK3 | 0.96202619 |
| 45 | CASK | 0.94758302 |
| 46 | OXSR1 | 0.94429921 |
| 47 | CSNK1G2 | 0.93989968 |
| 48 | PASK | 0.93380340 |
| 49 | BCR | 0.92710728 |
| 50 | MAPK13 | 0.89898216 |
| 51 | BRSK2 | 0.88329988 |
| 52 | AURKB | 0.87853131 |
| 53 | PINK1 | 0.87007085 |
| 54 | ERBB3 | 0.86604138 |
| 55 | PLK2 | 0.77798755 |
| 56 | FRK | 0.76417019 |
| 57 | CSNK1A1L | 0.72960201 |
| 58 | CCNB1 | 0.71984428 |
| 59 | TAOK3 | 0.70384925 |
| 60 | PRKCG | 0.68229266 |
| 61 | CHEK2 | 0.65427593 |
| 62 | AURKA | 0.65161392 |
| 63 | ATR | 0.64991388 |
| 64 | CDK8 | 0.63737849 |
| 65 | MYLK | 0.63497851 |
| 66 | OBSCN | 0.62845446 |
| 67 | STK38L | 0.62742408 |
| 68 | RPS6KA5 | 0.61824831 |
| 69 | CSNK2A1 | 0.61472298 |
| 70 | CSNK2A2 | 0.60697993 |
| 71 | TIE1 | 0.55705124 |
| 72 | WNK4 | 0.54645635 |
| 73 | MAPKAPK5 | 0.54218422 |
| 74 | PHKG1 | 0.53561980 |
| 75 | PHKG2 | 0.53561980 |
| 76 | PNCK | 0.53191636 |
| 77 | EPHA4 | 0.51762125 |
| 78 | ACVR1B | 0.50409837 |
| 79 | MINK1 | 0.50219899 |
| 80 | TGFBR1 | 0.49302215 |
| 81 | PRKCE | 0.49257592 |
| 82 | ILK | 0.48632540 |
| 83 | MARK1 | 0.48136994 |
| 84 | BRSK1 | 0.47270617 |
| 85 | EIF2AK2 | 0.45594492 |
| 86 | KDR | 0.45527910 |
| 87 | DAPK3 | 0.44793466 |
| 88 | ABL2 | 0.41612127 |
| 89 | MUSK | 0.41536177 |
| 90 | TESK2 | 0.41398171 |
| 91 | ATM | 0.41339529 |
| 92 | CDK3 | 0.41233860 |
| 93 | RPS6KA4 | 0.37897042 |
| 94 | STK4 | 0.37568654 |
| 95 | DAPK1 | 0.35980316 |
| 96 | EPHB2 | 0.35108000 |
| 97 | PAK3 | 0.33717013 |
| 98 | GRK7 | 0.33689606 |
| 99 | CSNK1E | 0.33572682 |
| 100 | CSNK1A1 | 0.33488825 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.65783563 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 4.56804418 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 4.33995637 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 4.02093944 |
| 5 | Protein export_Homo sapiens_hsa03060 | 3.25284435 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 3.01098700 |
| 7 | Huntingtons disease_Homo sapiens_hsa05016 | 2.82809265 |
| 8 | Alzheimers disease_Homo sapiens_hsa05010 | 2.68091559 |
| 9 | Mismatch repair_Homo sapiens_hsa03430 | 2.60791668 |
| 10 | Homologous recombination_Homo sapiens_hsa03440 | 2.36365128 |
| 11 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.26268388 |
| 12 | DNA replication_Homo sapiens_hsa03030 | 2.23913908 |
| 13 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.16343973 |
| 14 | Spliceosome_Homo sapiens_hsa03040 | 1.96889574 |
| 15 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.95515385 |
| 16 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.78313880 |
| 17 | Basal transcription factors_Homo sapiens_hsa03022 | 1.76848220 |
| 18 | Base excision repair_Homo sapiens_hsa03410 | 1.63003774 |
| 19 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.60425961 |
| 20 | RNA degradation_Homo sapiens_hsa03018 | 1.59769204 |
| 21 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.57630023 |
| 22 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.55104444 |
| 23 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.53194211 |
| 24 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.44719423 |
| 25 | RNA transport_Homo sapiens_hsa03013 | 1.39832868 |
| 26 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.33940027 |
| 27 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.33344237 |
| 28 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.30483354 |
| 29 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.30133065 |
| 30 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.29210357 |
| 31 | Purine metabolism_Homo sapiens_hsa00230 | 1.20218165 |
| 32 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.19658886 |
| 33 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.17486152 |
| 34 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.15067885 |
| 35 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.13317491 |
| 36 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.08517366 |
| 37 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.93447499 |
| 38 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.92416857 |
| 39 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.90027788 |
| 40 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.88085323 |
| 41 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.86906782 |
| 42 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.85890524 |
| 43 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.84882511 |
| 44 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.82737605 |
| 45 | Phototransduction_Homo sapiens_hsa04744 | 0.82122833 |
| 46 | Cell cycle_Homo sapiens_hsa04110 | 0.81476890 |
| 47 | Metabolic pathways_Homo sapiens_hsa01100 | 0.80558247 |
| 48 | Peroxisome_Homo sapiens_hsa04146 | 0.78220916 |
| 49 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.70581255 |
| 50 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.70252001 |
| 51 | Nicotine addiction_Homo sapiens_hsa05033 | 0.64651623 |
| 52 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.61818827 |
| 53 | Sulfur relay system_Homo sapiens_hsa04122 | 0.59620131 |
| 54 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.58080482 |
| 55 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.57860798 |
| 56 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.57734559 |
| 57 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.54206167 |
| 58 | Carbon metabolism_Homo sapiens_hsa01200 | 0.51053242 |
| 59 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.50816600 |
| 60 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.50424081 |
| 61 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.50150837 |
| 62 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.49685048 |
| 63 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.49460809 |
| 64 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.49064426 |
| 65 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.48577592 |
| 66 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.47787962 |
| 67 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.46888057 |
| 68 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.43114711 |
| 69 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.40652518 |
| 70 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.38723343 |
| 71 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.36325181 |
| 72 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.36317216 |
| 73 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.35857615 |
| 74 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.34082417 |
| 75 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.33958305 |
| 76 | Retinol metabolism_Homo sapiens_hsa00830 | 0.33178896 |
| 77 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.33138042 |
| 78 | Asthma_Homo sapiens_hsa05310 | 0.32928312 |
| 79 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.32485566 |
| 80 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.30920919 |
| 81 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.30429163 |
| 82 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.29864953 |
| 83 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.29657920 |
| 84 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.28853434 |
| 85 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.28185126 |
| 86 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.28177928 |
| 87 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.27331586 |
| 88 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.27264963 |
| 89 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.26319071 |
| 90 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.26205444 |
| 91 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.24793285 |
| 92 | Alcoholism_Homo sapiens_hsa05034 | 0.24020765 |
| 93 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.21488614 |
| 94 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.20900605 |
| 95 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.20181438 |
| 96 | Olfactory transduction_Homo sapiens_hsa04740 | 0.19686848 |
| 97 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.18875142 |
| 98 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.17413495 |
| 99 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.16991879 |
| 100 | Taste transduction_Homo sapiens_hsa04742 | 0.16287463 |

