HINT1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a protein that hydrolyzes purine nucleotide phosphoramidates substrates, including AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif. This gene is considered a tumor suppressor gene. In addition, mutations in this gene can cause autosomal recessive neuromyotonia and axonal neuropathy. There are several related pseudogenes on chromosome 7. Several transcript variants have been observed. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)9.76142413
2energy coupled proton transport, down electrochemical gradient (GO:0015985)9.33078368
3ATP synthesis coupled proton transport (GO:0015986)9.33078368
4mitochondrial electron transport, NADH to ubiquinone (GO:0006120)7.81195730
5respiratory electron transport chain (GO:0022904)7.46979140
6viral transcription (GO:0019083)7.41547000
7electron transport chain (GO:0022900)7.30994348
8translational termination (GO:0006415)7.12956689
9ribosomal small subunit biogenesis (GO:0042274)6.63760752
10SRP-dependent cotranslational protein targeting to membrane (GO:0006614)6.36975029
11cotranslational protein targeting to membrane (GO:0006613)6.33928083
12protein targeting to ER (GO:0045047)6.29589198
13ribosomal small subunit assembly (GO:0000028)6.19835760
14translational elongation (GO:0006414)6.18310006
15protein localization to endoplasmic reticulum (GO:0070972)5.97507548
16establishment of protein localization to endoplasmic reticulum (GO:0072599)5.96870542
17cellular protein complex disassembly (GO:0043624)5.80337008
18viral life cycle (GO:0019058)5.75923284
19nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)5.19030114
20ATP biosynthetic process (GO:0006754)5.15183867
21translational initiation (GO:0006413)5.14983826
22establishment of protein localization to mitochondrial membrane (GO:0090151)5.11116860
23chaperone-mediated protein transport (GO:0072321)5.09863852
24protein complex biogenesis (GO:0070271)5.03079703
25purine ribonucleoside triphosphate biosynthetic process (GO:0009206)4.95633341
26oxidative phosphorylation (GO:0006119)4.93977787
27protein neddylation (GO:0045116)4.91259132
28purine nucleoside triphosphate biosynthetic process (GO:0009145)4.90974997
29ribosomal large subunit biogenesis (GO:0042273)4.90387957
30protein complex disassembly (GO:0043241)4.89443700
31mitochondrial respiratory chain complex I assembly (GO:0032981)4.82673317
32NADH dehydrogenase complex assembly (GO:0010257)4.82673317
33mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.82673317
34mitochondrial respiratory chain complex assembly (GO:0033108)4.71483226
35macromolecular complex disassembly (GO:0032984)4.69063114
36translation (GO:0006412)4.61505722
37hydrogen ion transmembrane transport (GO:1902600)4.60838555
38inner mitochondrial membrane organization (GO:0007007)4.48274316
39ribonucleoside triphosphate biosynthetic process (GO:0009201)4.47004154
40maturation of SSU-rRNA (GO:0030490)4.41678456
41GTP biosynthetic process (GO:0006183)4.27206497
42protein targeting to membrane (GO:0006612)4.23770593
43nucleoside triphosphate biosynthetic process (GO:0009142)3.98038762
44regulation of mitochondrial translation (GO:0070129)3.95222095
45proton transport (GO:0015992)3.92540258
46aldehyde catabolic process (GO:0046185)3.91171139
47transcription elongation from RNA polymerase III promoter (GO:0006385)3.84458785
48termination of RNA polymerase III transcription (GO:0006386)3.84458785
49hydrogen transport (GO:0006818)3.84080927
50UTP biosynthetic process (GO:0006228)3.81739487
51protein targeting to mitochondrion (GO:0006626)3.78672349
52establishment of protein localization to mitochondrion (GO:0072655)3.77687612
53proteasome assembly (GO:0043248)3.76021829
54pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.68661876
55establishment of integrated proviral latency (GO:0075713)3.65090159
56sequestering of actin monomers (GO:0042989)3.64238524
57protein localization to mitochondrion (GO:0070585)3.62634983
58regulation of cellular amino acid metabolic process (GO:0006521)3.57070726
59guanosine-containing compound biosynthetic process (GO:1901070)3.56758144
60purine ribonucleoside monophosphate biosynthetic process (GO:0009168)3.55665513
61purine nucleoside monophosphate biosynthetic process (GO:0009127)3.55665513
62nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.55043435
63cellular component biogenesis (GO:0044085)3.54261537
64UTP metabolic process (GO:0046051)3.53397963
65nucleobase-containing small molecule interconversion (GO:0015949)3.52794962
66exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.49786785
67negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.47799250
68mitochondrial transport (GO:0006839)3.46563087
69RNA catabolic process (GO:0006401)3.46502391
70nuclear-transcribed mRNA catabolic process (GO:0000956)3.44318713
71regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.42454994
72respiratory chain complex IV assembly (GO:0008535)3.39200067
73ribonucleoprotein complex biogenesis (GO:0022613)3.36736865
74anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.36422927
75RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.29426066
76tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.29426066
77rRNA processing (GO:0006364)3.27287636
78cytochrome complex assembly (GO:0017004)3.26282219
79chromatin remodeling at centromere (GO:0031055)3.26129741
80negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.25140505
81negative regulation of ligase activity (GO:0051352)3.25140505
82DNA deamination (GO:0045006)3.23157409
83CENP-A containing nucleosome assembly (GO:0034080)3.22347144
84rRNA modification (GO:0000154)3.21437403
85mRNA catabolic process (GO:0006402)3.21374641
86regulation of oxidative phosphorylation (GO:0002082)3.20888650
87antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.19131048
88establishment of viral latency (GO:0019043)3.18966703
89DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.18804806
90establishment of protein localization to membrane (GO:0090150)3.18061268
91cellular ketone body metabolic process (GO:0046950)3.17389496
92regulation of cellular respiration (GO:0043457)3.15575158
93aerobic respiration (GO:0009060)3.14740364
94rRNA metabolic process (GO:0016072)3.14169791
95CTP metabolic process (GO:0046036)3.13693066
96CTP biosynthetic process (GO:0006241)3.13693066
97deoxyribose phosphate biosynthetic process (GO:0046385)3.13321591
982-deoxyribonucleotide biosynthetic process (GO:0009265)3.13321591
99pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.12373284
100positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.10416490
101signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.09241261
102intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.09241261
103spliceosomal snRNP assembly (GO:0000387)3.08788301
104deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.08725837
105protein targeting (GO:0006605)3.07801218
106signal transduction involved in DNA damage checkpoint (GO:0072422)3.05567371
107cullin deneddylation (GO:0010388)3.05180953
108purine nucleoside biosynthetic process (GO:0042451)3.04472870
109purine ribonucleoside biosynthetic process (GO:0046129)3.04472870
110positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.03637851
111de novo posttranslational protein folding (GO:0051084)3.03621665
112formation of translation preinitiation complex (GO:0001731)3.03427342
113ribonucleoside monophosphate biosynthetic process (GO:0009156)3.03014293
114de novo protein folding (GO:0006458)3.02463587
115pyrimidine nucleotide catabolic process (GO:0006244)3.02158783
116signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.02037748
117signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.02037748
118signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.02037748
119signal transduction involved in cell cycle checkpoint (GO:0072395)3.00771714
120antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.98179725
121nucleoside monophosphate biosynthetic process (GO:0009124)2.97950874
122signal transduction involved in DNA integrity checkpoint (GO:0072401)2.97898382

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat5.16379146
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.45316336
3* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.38380050
4* MYC_18555785_ChIP-Seq_MESCs_Mouse4.37482963
5GABP_17652178_ChIP-ChIP_JURKAT_Human4.16116176
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.95890216
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.66445059
8ETS1_20019798_ChIP-Seq_JURKAT_Human3.57380633
9NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.48713934
10CREB1_15753290_ChIP-ChIP_HEK293T_Human3.48427470
11HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.44807921
12* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.14472804
13* CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.10244701
14HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.05985500
15FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.88217323
16MYC_19079543_ChIP-ChIP_MESCs_Mouse2.86505851
17DCP1A_22483619_ChIP-Seq_HELA_Human2.71365676
18XRN2_22483619_ChIP-Seq_HELA_Human2.70093602
19* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.60667709
20E2F1_18555785_ChIP-Seq_MESCs_Mouse2.44338440
21THAP11_20581084_ChIP-Seq_MESCs_Mouse2.33537956
22VDR_23849224_ChIP-Seq_CD4+_Human2.29932197
23E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.27931708
24TTF2_22483619_ChIP-Seq_HELA_Human2.26354390
25ESRRB_18555785_ChIP-Seq_MESCs_Mouse2.26300537
26* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse2.24453021
27ZFP42_18358816_ChIP-ChIP_MESCs_Mouse2.17864703
28PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.14848706
29* YY1_21170310_ChIP-Seq_MESCs_Mouse2.14677956
30CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.13215446
31SRF_21415370_ChIP-Seq_HL-1_Mouse2.01340094
32PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.00693978
33FOXP3_21729870_ChIP-Seq_TREG_Human1.94898092
34ELK1_19687146_ChIP-ChIP_HELA_Human1.94645334
35E2F7_22180533_ChIP-Seq_HELA_Human1.94586521
36TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.88666204
37* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.87633596
38HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.83699995
39* GABP_19822575_ChIP-Seq_HepG2_Human1.80603248
40ELF1_17652178_ChIP-ChIP_JURKAT_Human1.77552330
41POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.66936996
42CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.63367103
43SRY_22984422_ChIP-ChIP_TESTIS_Rat1.62164815
44HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.60896300
45CTCF_18555785_ChIP-Seq_MESCs_Mouse1.55586915
46ELK1_22589737_ChIP-Seq_MCF10A_Human1.54555210
47E2F4_17652178_ChIP-ChIP_JURKAT_Human1.52644056
48FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.52007347
49POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.51967597
50* CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.51802082
51HOXB4_20404135_ChIP-ChIP_EML_Mouse1.51383874
52* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.43708257
53KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.38371749
54FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.37941321
55MYC_18940864_ChIP-ChIP_HL60_Human1.37856866
56HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.36321028
57* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.36269846
58FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.33490034
59BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.25674967
60SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.24655820
61CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.23446405
62MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.22364445
63E2F1_21310950_ChIP-Seq_MCF-7_Human1.19754827
64STAT3_1855785_ChIP-Seq_MESCs_Mouse1.19583556
65* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.19461216
66* OCT4_18692474_ChIP-Seq_MEFs_Mouse1.16731837
67* KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.15314442
68ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.14520252
69POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.14122300
70CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.10231731
71CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.09532492
72VDR_22108803_ChIP-Seq_LS180_Human1.07549439
73ERG_20887958_ChIP-Seq_HPC-7_Mouse1.07355373
74SOX2_18692474_ChIP-Seq_MEFs_Mouse1.04750268
75EWS_26573619_Chip-Seq_HEK293_Human1.03189743
76PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.02174876
77FUS_26573619_Chip-Seq_HEK293_Human1.01780271
78CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.00020775
79NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.98730488
80MYCN_18555785_ChIP-Seq_MESCs_Mouse0.97827763
81SOX17_20123909_ChIP-Seq_XEN_Mouse0.96605829
82ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.95874701
83SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.95757675
84PADI4_21655091_ChIP-ChIP_MCF-7_Human0.94491331
85NANOG_18555785_ChIP-Seq_MESCs_Mouse0.94135582
86NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.93271464
87E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.92604804
88TP53_22573176_ChIP-Seq_HFKS_Human0.90689049
89YY1_22570637_ChIP-Seq_MALME-3M_Human0.90335844
90SOX2_18555785_ChIP-Seq_MESCs_Mouse0.90265183
91AR_21909140_ChIP-Seq_LNCAP_Human0.89835047
92IRF1_19129219_ChIP-ChIP_H3396_Human0.89506565
93ZNF274_21170338_ChIP-Seq_K562_Hela0.89295050
94RBPJ_22232070_ChIP-Seq_NCS_Mouse0.89220341
95YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.87935768
96FOXP1_21924763_ChIP-Seq_HESCs_Human0.87882318
97PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.87517569
98SOX2_16153702_ChIP-ChIP_HESCs_Human0.84657201
99TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.84361125
100EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.82596039
101SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.82337794
102ZNF263_19887448_ChIP-Seq_K562_Human0.81693229
103CIITA_25753668_ChIP-Seq_RAJI_Human0.77254821
104BMI1_23680149_ChIP-Seq_NPCS_Mouse0.75441994
105STAT1_20625510_ChIP-Seq_HELA_Human0.75056736
106NANOG_16153702_ChIP-ChIP_HESCs_Human0.74830385
107CTCF_26484167_Chip-Seq_Bcells_Mouse0.74321756
108RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.73782385
109TET1_21451524_ChIP-Seq_MESCs_Mouse0.73635566
110KDM5A_27292631_Chip-Seq_BREAST_Human0.72747750
111ERG_20517297_ChIP-Seq_VCAP_Human0.72620162
112MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.72452262
113HTT_18923047_ChIP-ChIP_STHdh_Human0.72150336
114MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.70721047
115EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.70417416
116FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.69281629
117CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.68891995
118POU5F1_16153702_ChIP-ChIP_HESCs_Human0.64313433
119* FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.63647327
120* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.62409135

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation6.16554084
2MP0001529_abnormal_vocalization3.76727704
3MP0003806_abnormal_nucleotide_metabolis3.61576682
4MP0006276_abnormal_autonomic_nervous3.50218741
5MP0006036_abnormal_mitochondrial_physio3.39677141
6MP0003693_abnormal_embryo_hatching3.10049330
7MP0002736_abnormal_nociception_after3.08640188
8MP0003186_abnormal_redox_activity3.01728364
9MP0006292_abnormal_olfactory_placode2.92367290
10MP0008058_abnormal_DNA_repair2.90860785
11MP0002735_abnormal_chemical_nociception2.79497812
12MP0006035_abnormal_mitochondrial_morpho2.77259943
13MP0001968_abnormal_touch/_nociception2.68730060
14MP0005360_urolithiasis2.35046339
15MP0004957_abnormal_blastocyst_morpholog2.34435354
16MP0001905_abnormal_dopamine_level2.33874369
17MP0005083_abnormal_biliary_tract2.28106289
18MP0002638_abnormal_pupillary_reflex2.15179992
19MP0002139_abnormal_hepatobiliary_system2.03961295
20MP0002837_dystrophic_cardiac_calcinosis1.87160599
21MP0008932_abnormal_embryonic_tissue1.83792035
22MP0005636_abnormal_mineral_homeostasis1.83643761
23MP0008877_abnormal_DNA_methylation1.82007078
24MP0004142_abnormal_muscle_tone1.81080999
25MP0001970_abnormal_pain_threshold1.80200533
26MP0002733_abnormal_thermal_nociception1.75400857
27MP0003880_abnormal_central_pattern1.75082991
28MP0008875_abnormal_xenobiotic_pharmacok1.73257442
29MP0000372_irregular_coat_pigmentation1.72740410
30MP0002751_abnormal_autonomic_nervous1.71325556
31MP0003786_premature_aging1.71125634
32MP0001984_abnormal_olfaction1.67780055
33MP0005084_abnormal_gallbladder_morpholo1.66831446
34MP0004147_increased_porphyrin_level1.64870669
35MP0002234_abnormal_pharynx_morphology1.61219010
36MP0002734_abnormal_mechanical_nocicepti1.61188684
37MP0002822_catalepsy1.59677773
38MP0010386_abnormal_urinary_bladder1.58716553
39MP0000538_abnormal_urinary_bladder1.56623552
40MP0001986_abnormal_taste_sensitivity1.55935292
41MP0003111_abnormal_nucleus_morphology1.55085139
42MP0005408_hypopigmentation1.54280013
43MP0001727_abnormal_embryo_implantation1.53332313
44MP0008995_early_reproductive_senescence1.52565406
45MP0003315_abnormal_perineum_morphology1.50216036
46MP0005499_abnormal_olfactory_system1.47530222
47MP0005394_taste/olfaction_phenotype1.47530222
48MP0005085_abnormal_gallbladder_physiolo1.45702206
49MP0000358_abnormal_cell_content/1.37693553
50MP0003718_maternal_effect1.36828547
51MP0001293_anophthalmia1.36135658
52MP0003121_genomic_imprinting1.34849554
53MP0001440_abnormal_grooming_behavior1.34452235
54MP0005646_abnormal_pituitary_gland1.29251679
55MP0005332_abnormal_amino_acid1.28950394
56MP0005551_abnormal_eye_electrophysiolog1.28153930
57MP0008872_abnormal_physiological_respon1.27014676
58MP0003195_calcinosis1.25738680
59MP0002163_abnormal_gland_morphology1.25309268
60MP0002095_abnormal_skin_pigmentation1.24424933
61MP0002160_abnormal_reproductive_system1.24171351
62MP0000566_synostosis1.23961995
63MP0003787_abnormal_imprinting1.23162117
64MP0008007_abnormal_cellular_replicative1.21140622
65MP0005075_abnormal_melanosome_morpholog1.20808201
66MP0005266_abnormal_metabolism1.19674912
67MP0010030_abnormal_orbit_morphology1.18149542
68MP0000631_abnormal_neuroendocrine_gland1.17735138
69MP0009046_muscle_twitch1.17222852
70MP0003123_paternal_imprinting1.15515863
71MP0001663_abnormal_digestive_system1.13864419
72MP0005645_abnormal_hypothalamus_physiol1.13857944
73MP0001764_abnormal_homeostasis1.13339263
74MP0008789_abnormal_olfactory_epithelium1.11126739
75MP0005379_endocrine/exocrine_gland_phen1.10850331
76MP0002210_abnormal_sex_determination1.09545462
77MP0003646_muscle_fatigue1.08956003
78MP0003122_maternal_imprinting1.08534441
79MP0002184_abnormal_innervation1.07169041
80MP0002938_white_spotting1.05602227
81MP0003283_abnormal_digestive_organ1.04401026
82MP0003656_abnormal_erythrocyte_physiolo1.03933953
83MP0003136_yellow_coat_color1.03682045
84MP0005381_digestive/alimentary_phenotyp0.99665630
85MP0005376_homeostasis/metabolism_phenot0.99188913
86MP0002272_abnormal_nervous_system0.94865577
87MP0000751_myopathy0.94298015
88MP0001756_abnormal_urination0.92986375
89MP0004145_abnormal_muscle_electrophysio0.92591114
90MP0003567_abnormal_fetal_cardiomyocyte0.92470646
91MP0005253_abnormal_eye_physiology0.92310144
92MP0004924_abnormal_behavior0.91755132
93MP0005386_behavior/neurological_phenoty0.91755132
94MP0001664_abnormal_digestion0.91637849
95MP0009643_abnormal_urine_homeostasis0.91287559
96MP0001929_abnormal_gametogenesis0.91180202
97MP0002132_abnormal_respiratory_system0.90873272
98MP0002277_abnormal_respiratory_mucosa0.86920705
99MP0000653_abnormal_sex_gland0.85918957
100MP0001145_abnormal_male_reproductive0.85712518
101MP0009697_abnormal_copulation0.84777570
102MP0005584_abnormal_enzyme/coenzyme_acti0.84271861
103MP0005174_abnormal_tail_pigmentation0.84128307
104MP0002653_abnormal_ependyma_morphology0.82324817
105MP0004270_analgesia0.81194999
106MP0004043_abnormal_pH_regulation0.80613051
107MP0005410_abnormal_fertilization0.79418264
108MP0004883_abnormal_blood_vessel0.77317308
109MP0000049_abnormal_middle_ear0.76217608
110MP0001919_abnormal_reproductive_system0.75037550
111MP0001188_hyperpigmentation0.74913844
112MP0006072_abnormal_retinal_apoptosis0.74769136
113MP0003011_delayed_dark_adaptation0.73552874
114MP0005423_abnormal_somatic_nervous0.72925665
115MP0003638_abnormal_response/metabolism_0.71877310
116MP0003077_abnormal_cell_cycle0.71690641
117MP0001542_abnormal_bone_strength0.71660566
118MP0000749_muscle_degeneration0.71633139
119MP0000537_abnormal_urethra_morphology0.70384478
120MP0002332_abnormal_exercise_endurance0.69796107
121MP0002067_abnormal_sensory_capabilities0.69715632
122MP0000490_abnormal_crypts_of0.69338103
123MP0002064_seizures0.69232430
124MP0003698_abnormal_male_reproductive0.68335766
125MP0005195_abnormal_posterior_eye0.68100625
126MP0001485_abnormal_pinna_reflex0.68048361
127MP0010094_abnormal_chromosome_stability0.67655595
128MP0002876_abnormal_thyroid_physiology0.67621284
129MP0009333_abnormal_splenocyte_physiolog0.67435986
130MP0005319_abnormal_enzyme/_coenzyme0.66916431
131MP0002090_abnormal_vision0.66885444
132MP0002557_abnormal_social/conspecific_i0.66574406
133MP0002572_abnormal_emotion/affect_behav0.66227414
134MP0001286_abnormal_eye_development0.66211591
135MP0002102_abnormal_ear_morphology0.65447051
136MP0009745_abnormal_behavioral_response0.65184688
137MP0005389_reproductive_system_phenotype0.64488390
138MP0004742_abnormal_vestibular_system0.64487453
139MP0005535_abnormal_body_temperature0.64116050
140MP0005377_hearing/vestibular/ear_phenot0.63668899
141MP0003878_abnormal_ear_physiology0.63668899
142MP0002233_abnormal_nose_morphology0.62798261
143MP0000750_abnormal_muscle_regeneration0.62224721
144MP0004133_heterotaxia0.61962024

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)8.06893179
2Abnormal mitochondria in muscle tissue (HP:0008316)7.43715451
3Acute encephalopathy (HP:0006846)6.90674877
4Mitochondrial inheritance (HP:0001427)6.87454776
5Progressive macrocephaly (HP:0004481)6.68371950
6Abnormality of cells of the erythroid lineage (HP:0012130)6.08036129
7Increased CSF lactate (HP:0002490)5.89251661
8Hepatocellular necrosis (HP:0001404)5.76997932
9Cerebral edema (HP:0002181)5.19937537
10Hepatic necrosis (HP:0002605)5.17449653
11Abnormal number of erythroid precursors (HP:0012131)5.04764496
12Increased hepatocellular lipid droplets (HP:0006565)4.95007159
13Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)4.79131753
14Decreased activity of mitochondrial respiratory chain (HP:0008972)4.74710781
15Abnormal activity of mitochondrial respiratory chain (HP:0011922)4.74710781
16Lipid accumulation in hepatocytes (HP:0006561)4.60658656
17Reticulocytopenia (HP:0001896)4.34324965
18Increased intramyocellular lipid droplets (HP:0012240)4.33574946
19Respiratory failure (HP:0002878)4.25924926
20Macrocytic anemia (HP:0001972)4.21817148
21Renal Fanconi syndrome (HP:0001994)4.14950215
22Exercise intolerance (HP:0003546)4.14130875
23Muscle abnormality related to mitochondrial dysfunction (HP:0003800)4.12229741
24Lactic acidosis (HP:0003128)4.06778719
25Abnormality of glycolysis (HP:0004366)4.02773333
26Increased serum pyruvate (HP:0003542)4.02773333
27Optic disc pallor (HP:0000543)3.99211962
283-Methylglutaconic aciduria (HP:0003535)3.93074063
29Leukodystrophy (HP:0002415)3.88046193
30Increased serum lactate (HP:0002151)3.80164934
31Increased muscle lipid content (HP:0009058)3.79107929
32Pallor (HP:0000980)3.60278752
33Exertional dyspnea (HP:0002875)3.38113843
34Respiratory difficulties (HP:0002880)2.93785500
35Hyperphosphaturia (HP:0003109)2.90573415
36Neuroendocrine neoplasm (HP:0100634)2.85738584
37Lethargy (HP:0001254)2.81849346
38Pheochromocytoma (HP:0002666)2.76192039
39Abnormality of renal resorption (HP:0011038)2.75879812
40Emotional lability (HP:0000712)2.74594183
41CNS demyelination (HP:0007305)2.62462760
42Abnormal hemoglobin (HP:0011902)2.62006829
43Abnormality of urine glucose concentration (HP:0011016)2.58508157
44Glycosuria (HP:0003076)2.58508157
45Conjunctival hamartoma (HP:0100780)2.53888852
46X-linked dominant inheritance (HP:0001423)2.48600137
47Congenital, generalized hypertrichosis (HP:0004540)2.35447047
48Abnormality of midbrain morphology (HP:0002418)2.32748601
49Molar tooth sign on MRI (HP:0002419)2.32748601
50Hypothermia (HP:0002045)2.32509009
51Abnormal urine phosphate concentration (HP:0012599)2.29253727
52Palpitations (HP:0001962)2.26714223
53Methylmalonic acidemia (HP:0002912)2.25429835
54Pancreatic fibrosis (HP:0100732)2.25052388
55Hyperglycinemia (HP:0002154)2.22969701
56Abnormality of aromatic amino acid family metabolism (HP:0004338)2.21071026
57Colon cancer (HP:0003003)2.17934400
58Pancreatic cysts (HP:0001737)2.17913384
59Abnormality of placental membranes (HP:0011409)2.16550162
60Amniotic constriction ring (HP:0009775)2.16550162
61Limb dystonia (HP:0002451)2.11347430
62Vomiting (HP:0002013)2.09883784
63Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.07096145
64Abnormal protein N-linked glycosylation (HP:0012347)2.07096145
65Abnormal protein glycosylation (HP:0012346)2.07096145
66Abnormal glycosylation (HP:0012345)2.07096145
67Medial flaring of the eyebrow (HP:0010747)2.04198522
68Ragged-red muscle fibers (HP:0003200)2.00131957
69Multiple enchondromatosis (HP:0005701)2.00007239
70Absent thumb (HP:0009777)1.99683663
71Pancytopenia (HP:0001876)1.99331851
72Microvesicular hepatic steatosis (HP:0001414)1.97147746
73Aplasia/Hypoplasia of the sacrum (HP:0008517)1.96451737
74Abnormal gallbladder physiology (HP:0012438)1.96157577
75Cholecystitis (HP:0001082)1.96157577
76Poor suck (HP:0002033)1.95387606
77Gliosis (HP:0002171)1.94263490
78True hermaphroditism (HP:0010459)1.93055172
79Blindness (HP:0000618)1.91261261
80Abnormality of serum amino acid levels (HP:0003112)1.89822954
81Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.89154208
82Abnormality of alanine metabolism (HP:0010916)1.89154208
83Hyperalaninemia (HP:0003348)1.89154208
84Abnormality of aspartate family amino acid metabolism (HP:0010899)1.88728190
85Oral leukoplakia (HP:0002745)1.88427733
86Reduced antithrombin III activity (HP:0001976)1.88149640
87Abnormality of methionine metabolism (HP:0010901)1.87294603
88Dicarboxylic aciduria (HP:0003215)1.87246708
89Abnormality of dicarboxylic acid metabolism (HP:0010995)1.87246708
90Neoplasm of head and neck (HP:0012288)1.85985747
91Esophageal neoplasm (HP:0100751)1.85985747
92Aplastic anemia (HP:0001915)1.84712232
93Degeneration of anterior horn cells (HP:0002398)1.84698633
94Abnormality of the anterior horn cell (HP:0006802)1.84698633
95Cleft eyelid (HP:0000625)1.80831028
96Abnormal pupillary function (HP:0007686)1.80358458
97Abnormality of the vocal cords (HP:0008777)1.79099140
98Sclerocornea (HP:0000647)1.78586932
99Abnormality of the labia minora (HP:0012880)1.77633932
100Triphalangeal thumb (HP:0001199)1.76749894
101Abnormality of reticulocytes (HP:0004312)1.74801183
102Renal tubular dysfunction (HP:0000124)1.73852933
103Megaloblastic anemia (HP:0001889)1.69963848
104Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.68307694
105Aplasia/hypoplasia of the uterus (HP:0008684)1.67197083
106Gait imbalance (HP:0002141)1.62642497
107Congenital primary aphakia (HP:0007707)1.61484676
108Neoplasm of the peripheral nervous system (HP:0100007)1.60800934
109Nephronophthisis (HP:0000090)1.59939114
110Abnormality of magnesium homeostasis (HP:0004921)1.59277170
111Testicular atrophy (HP:0000029)1.57549312
112Hyperglycinuria (HP:0003108)1.56333401
113Neoplasm of the adrenal gland (HP:0100631)1.54038737
114Methylmalonic aciduria (HP:0012120)1.54037467
115Nausea (HP:0002018)1.52130196
116Hypobetalipoproteinemia (HP:0003563)1.49537338
117Progressive external ophthalmoplegia (HP:0000590)1.48095620
118* Myokymia (HP:0002411)1.47567186
119Trismus (HP:0000211)1.47093805
120Carpal bone hypoplasia (HP:0001498)1.44849240
121Congenital ichthyosiform erythroderma (HP:0007431)1.42198680
122Hypokinesia (HP:0002375)1.42147906
123Angiofibromas (HP:0010615)1.40686931
124Adenoma sebaceum (HP:0009720)1.40686931
125Type I transferrin isoform profile (HP:0003642)1.39518697
126Delusions (HP:0000746)1.38960016
127Generalized aminoaciduria (HP:0002909)1.38922998
128Depressed nasal ridge (HP:0000457)1.37713619
129Microretrognathia (HP:0000308)1.37345322
130Cerebral hypomyelination (HP:0006808)1.36604837
131Rhabdomyolysis (HP:0003201)1.36431457
132Stenosis of the external auditory canal (HP:0000402)1.35192764
133Abnormal autonomic nervous system physiology (HP:0012332)1.33329248
134Orthostatic hypotension (HP:0001278)1.33029513
135Metabolic acidosis (HP:0001942)1.30173536
136Abnormality of fatty-acid metabolism (HP:0004359)1.29546051

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NME25.84670113
2VRK25.20066492
3STK163.49885848
4LIMK13.28382047
5NME13.26801118
6MAP3K123.19097887
7ARAF2.98850496
8BUB12.90450453
9PIM22.55937691
10TESK22.50118233
11TLK12.49138695
12ZAK2.39262643
13GRK52.36717386
14EIF2AK12.27287939
15TESK12.25249352
16VRK12.12920095
17NUAK11.92594625
18MYLK1.92235471
19WEE11.85425363
20PBK1.74253986
21MST41.66864688
22BCKDK1.64237319
23BRAF1.58687439
24NEK11.56790693
25ILK1.46750602
26PLK41.39741200
27ABL21.38156453
28PDK21.34076169
29TAF11.31978129
30TTK1.29756708
31EIF2AK31.23720196
32AURKA1.22966761
33MAP4K21.22641894
34DAPK31.18902505
35SRPK11.17055535
36UHMK11.16405211
37GRK71.09384317
38WNK41.08649135
39ADRBK21.06378167
40CASK1.06102729
41DYRK21.05977318
42LRRK21.05258353
43CCNB11.01581858
44RPS6KB20.95321338
45GRK10.95029766
46TRIM280.94856741
47ADRBK10.94819689
48CHEK20.94296249
49GRK60.93222298
50CDK80.91998461
51CSNK1G10.89177228
52CSNK1G20.88957948
53MAP2K20.88619433
54PAK10.85119532
55BMPR1B0.84131644
56MST1R0.83854991
57DAPK10.83657432
58MAP3K110.83435650
59MAPKAPK50.83370574
60CDK190.82059743
61CSNK1G30.79563774
62ATR0.78194679
63MKNK10.77519629
64CDK140.74559877
65PAK40.72980416
66AURKB0.72461627
67CSNK2A10.69728917
68CSNK2A20.69409021
69CAMK2B0.67754294
70CDC70.66180598
71CDK180.65649829
72MAPKAPK30.65543745
73CSNK1A1L0.65137598
74MINK10.64999432
75CAMK2D0.63684389
76CDK150.63648883
77CDK11A0.62864976
78MAPK130.61659105
79MAP2K70.61381266
80PRKCG0.61072507
81CAMK2G0.60545150
82MAP3K40.59772312
83PHKG20.59759480
84PHKG10.59759480
85TAOK30.59446213
86PLK10.59111643
87WNK30.57958885
88ACVR1B0.55760304
89MAP2K60.55267269
90BRSK20.54813026
91PRKCI0.53565358
92RPS6KA40.53040566
93STK390.52973570
94NEK20.52945428
95EIF2AK20.52487742
96OXSR10.51455703
97INSRR0.51317323
98KDR0.50045600
99CAMKK20.49313594
100TSSK60.48517157
101FLT30.48423614
102PINK10.47945973
103BRSK10.47446682
104OBSCN0.47416622
105SCYL20.47170691
106LMTK20.46467961
107PRKG20.45958568
108PLK20.45146027
109MAPK40.43049895
110RPS6KA50.42736311
111TGFBR10.42210960
112CSNK1E0.42105836
113ROCK20.41842114
114MUSK0.41424844
115MAP2K10.39470737
116PLK30.39178979
117DYRK30.37829231
118EPHA40.36978970
119MATK0.36762784
120ATM0.36730250
121PRKACA0.36423409
122CDK70.36343389
123CSNK1A10.36078038
124KSR20.35558765
125RPS6KC10.34579328
126RPS6KL10.34579328
127CDK30.33597980
128ERBB30.33513876
129MAP3K80.32732014
130EPHB20.32609822
131PIK3CG0.32279461
132MARK10.31620251
133CAMK2A0.31221486
134BCR0.29479255
135PASK0.29386518

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001906.12518921
2Ribosome_Homo sapiens_hsa030105.51831093
3Parkinsons disease_Homo sapiens_hsa050125.47246274
4Alzheimers disease_Homo sapiens_hsa050103.90667165
5Huntingtons disease_Homo sapiens_hsa050163.82638914
6Proteasome_Homo sapiens_hsa030503.61904694
7Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049323.42533496
8Cardiac muscle contraction_Homo sapiens_hsa042602.38448347
9Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.27204688
10Protein export_Homo sapiens_hsa030602.13944664
11RNA polymerase_Homo sapiens_hsa030202.07769956
12Sulfur metabolism_Homo sapiens_hsa009201.82003788
13Pyrimidine metabolism_Homo sapiens_hsa002401.74511353
14Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.72912220
15DNA replication_Homo sapiens_hsa030301.72211428
16Mismatch repair_Homo sapiens_hsa034301.40321268
17Collecting duct acid secretion_Homo sapiens_hsa049661.34991507
18Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.28728065
19Fanconi anemia pathway_Homo sapiens_hsa034601.27130495
20Pyruvate metabolism_Homo sapiens_hsa006201.25383689
21Sulfur relay system_Homo sapiens_hsa041221.23780577
22Spliceosome_Homo sapiens_hsa030401.20998941
23Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.19248075
24Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.15290279
25Nucleotide excision repair_Homo sapiens_hsa034201.13467034
26Carbon metabolism_Homo sapiens_hsa012001.10746429
27Glutathione metabolism_Homo sapiens_hsa004801.09838784
282-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.02782975
29Vibrio cholerae infection_Homo sapiens_hsa051100.99365137
30Tyrosine metabolism_Homo sapiens_hsa003500.97137268
31Butanoate metabolism_Homo sapiens_hsa006500.94849014
32Phenylalanine metabolism_Homo sapiens_hsa003600.93802779
33Homologous recombination_Homo sapiens_hsa034400.93700217
34Metabolic pathways_Homo sapiens_hsa011000.89889881
35Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.89885701
36Drug metabolism - other enzymes_Homo sapiens_hsa009830.89085436
37Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.89073892
38Non-homologous end-joining_Homo sapiens_hsa034500.88144063
39Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.86911858
40Folate biosynthesis_Homo sapiens_hsa007900.82306257
41Purine metabolism_Homo sapiens_hsa002300.81317097
42Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.81200078
43Base excision repair_Homo sapiens_hsa034100.79762564
44Fatty acid elongation_Homo sapiens_hsa000620.77790600
45Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.77271593
46Propanoate metabolism_Homo sapiens_hsa006400.76307095
47Pentose phosphate pathway_Homo sapiens_hsa000300.75206711
48Systemic lupus erythematosus_Homo sapiens_hsa053220.71844068
49Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.70183968
50Maturity onset diabetes of the young_Homo sapiens_hsa049500.70170174
51Chemical carcinogenesis_Homo sapiens_hsa052040.69743024
52Asthma_Homo sapiens_hsa053100.67905497
53One carbon pool by folate_Homo sapiens_hsa006700.67809826
54Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.67040749
55Phototransduction_Homo sapiens_hsa047440.67027590
56Cysteine and methionine metabolism_Homo sapiens_hsa002700.66986946
57Pentose and glucuronate interconversions_Homo sapiens_hsa000400.66484567
58RNA transport_Homo sapiens_hsa030130.65581581
59Caffeine metabolism_Homo sapiens_hsa002320.64070536
60Vitamin B6 metabolism_Homo sapiens_hsa007500.63739470
61Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.63385678
62Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.63082402
63Biosynthesis of amino acids_Homo sapiens_hsa012300.63048943
64Peroxisome_Homo sapiens_hsa041460.60419343
65Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.59614004
66Cyanoamino acid metabolism_Homo sapiens_hsa004600.59279526
67Fructose and mannose metabolism_Homo sapiens_hsa000510.58997668
68Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.57079352
69Synaptic vesicle cycle_Homo sapiens_hsa047210.56882013
70Histidine metabolism_Homo sapiens_hsa003400.52641016
71Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.51546319
72Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.46517927
73Selenocompound metabolism_Homo sapiens_hsa004500.45947155
74Arginine and proline metabolism_Homo sapiens_hsa003300.44847922
75Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.42046654
76Alcoholism_Homo sapiens_hsa050340.41705362
77Phagosome_Homo sapiens_hsa041450.38405786
78Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.38235617
79Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.36855702
80Steroid hormone biosynthesis_Homo sapiens_hsa001400.36771770
81Nitrogen metabolism_Homo sapiens_hsa009100.36666592
82Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.35667680
83Steroid biosynthesis_Homo sapiens_hsa001000.35341073
84Nicotine addiction_Homo sapiens_hsa050330.35314629
85Primary bile acid biosynthesis_Homo sapiens_hsa001200.35155958
86Basal transcription factors_Homo sapiens_hsa030220.34692770
87Regulation of autophagy_Homo sapiens_hsa041400.34108243
88Oocyte meiosis_Homo sapiens_hsa041140.32135515
89Fatty acid metabolism_Homo sapiens_hsa012120.31386560
90Tryptophan metabolism_Homo sapiens_hsa003800.30256067
91Vitamin digestion and absorption_Homo sapiens_hsa049770.30250386
92p53 signaling pathway_Homo sapiens_hsa041150.30197446
93Arachidonic acid metabolism_Homo sapiens_hsa005900.30099752
94RNA degradation_Homo sapiens_hsa030180.29351546
95Fatty acid degradation_Homo sapiens_hsa000710.29010056
96Intestinal immune network for IgA production_Homo sapiens_hsa046720.28793658
97Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.28588284
98Rheumatoid arthritis_Homo sapiens_hsa053230.27741439
99Galactose metabolism_Homo sapiens_hsa000520.26259582
100beta-Alanine metabolism_Homo sapiens_hsa004100.25116507
101Fat digestion and absorption_Homo sapiens_hsa049750.24292931
102Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.24133444
103Linoleic acid metabolism_Homo sapiens_hsa005910.23368473
104Type I diabetes mellitus_Homo sapiens_hsa049400.21942362
105mRNA surveillance pathway_Homo sapiens_hsa030150.21530619
106Mineral absorption_Homo sapiens_hsa049780.18763419
107Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.17689786
108Retinol metabolism_Homo sapiens_hsa008300.17606239
109SNARE interactions in vesicular transport_Homo sapiens_hsa041300.16381292
110Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.11103825
111Starch and sucrose metabolism_Homo sapiens_hsa005000.11023560
112Cell cycle_Homo sapiens_hsa041100.10974929
113Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.10926308
114N-Glycan biosynthesis_Homo sapiens_hsa005100.10852750
115Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.10520596
116Epstein-Barr virus infection_Homo sapiens_hsa051690.10485049
117Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.10329600
118alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.06315255
119Arginine biosynthesis_Homo sapiens_hsa002200.05078279
120Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.02482235
121Taste transduction_Homo sapiens_hsa047420.02421846

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