HIST1H2AB

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA replication-dependent nucleosome assembly (GO:0006335)8.26753949
2DNA replication-dependent nucleosome organization (GO:0034723)8.26753949
3chromatin assembly (GO:0031497)6.65592259
4nucleosome assembly (GO:0006334)6.43657858
5regulation of histone H3-K9 methylation (GO:0051570)6.20049909
6DNA unwinding involved in DNA replication (GO:0006268)5.75882625
7protein localization to kinetochore (GO:0034501)5.75179574
8mitotic chromosome condensation (GO:0007076)5.60992823
9nucleosome organization (GO:0034728)5.56938716
10protein-DNA complex assembly (GO:0065004)5.49140055
11chromatin assembly or disassembly (GO:0006333)5.48039727
12nuclear pore complex assembly (GO:0051292)5.37211873
13nuclear pore organization (GO:0006999)5.32462868
14sister chromatid segregation (GO:0000819)5.13992108
15protein localization to chromosome, centromeric region (GO:0071459)4.98757356
16protein-DNA complex subunit organization (GO:0071824)4.91072962
17antibacterial humoral response (GO:0019731)4.87976564
18regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.87278670
19mitotic sister chromatid segregation (GO:0000070)4.79631368
20CENP-A containing nucleosome assembly (GO:0034080)4.79117312
21chromatin remodeling at centromere (GO:0031055)4.77464762
22DNA replication initiation (GO:0006270)4.71501483
23innate immune response in mucosa (GO:0002227)4.63735240
24negative regulation of hematopoietic progenitor cell differentiation (GO:1901533)4.57014099
25antimicrobial humoral response (GO:0019730)4.55238772
26DNA strand elongation involved in DNA replication (GO:0006271)4.54264974
27kinetochore organization (GO:0051383)4.44518540
28telomere maintenance via semi-conservative replication (GO:0032201)4.41515490
29DNA strand elongation (GO:0022616)4.32007435
30folic acid-containing compound biosynthetic process (GO:0009396)4.29158070
31DNA replication-independent nucleosome assembly (GO:0006336)4.28552682
32DNA replication-independent nucleosome organization (GO:0034724)4.28552682
33mitotic recombination (GO:0006312)4.22622953
34pore complex assembly (GO:0046931)4.13297143
35mitotic nuclear envelope disassembly (GO:0007077)4.12059089
36regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.08435966
37attachment of spindle microtubules to kinetochore (GO:0008608)4.02241536
38telomere maintenance via recombination (GO:0000722)3.99321290
39protein K6-linked ubiquitination (GO:0085020)3.99253640
40protoporphyrinogen IX metabolic process (GO:0046501)3.95282463
41DNA geometric change (GO:0032392)3.94248784
42DNA duplex unwinding (GO:0032508)3.94172378
43regulation of DNA endoreduplication (GO:0032875)3.91668594
44regulation of centriole replication (GO:0046599)3.90835733
45histone exchange (GO:0043486)3.90834352
46membrane disassembly (GO:0030397)3.88668518
47nuclear envelope disassembly (GO:0051081)3.88668518
48meiotic chromosome segregation (GO:0045132)3.86883929
49viral mRNA export from host cell nucleus (GO:0046784)3.85613489
50IMP biosynthetic process (GO:0006188)3.79408513
51regulation of gene silencing (GO:0060968)3.76524450
52positive regulation of chromosome segregation (GO:0051984)3.74424299
53positive regulation of mitotic sister chromatid separation (GO:1901970)3.71029149
54positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.71029149
55positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.71029149
56chromosome condensation (GO:0030261)3.70986796
57dosage compensation (GO:0007549)3.70017429
58mitotic sister chromatid cohesion (GO:0007064)3.68960944
59regulation of centrosome cycle (GO:0046605)3.67855610
60negative regulation of histone methylation (GO:0031061)3.67199167
61mitotic metaphase plate congression (GO:0007080)3.66190975
62nucleotide-excision repair, DNA gap filling (GO:0006297)3.59534461
63protoporphyrinogen IX biosynthetic process (GO:0006782)3.57493583
64regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.56823941
65translesion synthesis (GO:0019985)3.56144222
66regulation of spindle organization (GO:0090224)3.53146756
67DNA replication checkpoint (GO:0000076)3.52457789
68DNA topological change (GO:0006265)3.52311445
69metaphase plate congression (GO:0051310)3.51417565
70mucosal immune response (GO:0002385)3.50327582
71double-strand break repair via nonhomologous end joining (GO:0006303)3.45697167
72non-recombinational repair (GO:0000726)3.45697167
73regulation of sister chromatid cohesion (GO:0007063)3.44101347
74protein localization to chromosome (GO:0034502)3.44093561
75defense response to Gram-positive bacterium (GO:0050830)3.42270918
76IMP metabolic process (GO:0046040)3.40129035
77telomere maintenance via telomere lengthening (GO:0010833)3.37660345
78DNA conformation change (GO:0071103)3.36414555
79chromosome segregation (GO:0007059)3.35716872
80microtubule depolymerization (GO:0007019)3.35553182
81regulation of mammary gland epithelial cell proliferation (GO:0033599)3.34299687
82kinetochore assembly (GO:0051382)3.34077830
83regulation of megakaryocyte differentiation (GO:0045652)3.33996802
84regulation of chromosome segregation (GO:0051983)3.31381769
85telomere maintenance (GO:0000723)3.31379898
86organ or tissue specific immune response (GO:0002251)3.30991267
87postreplication repair (GO:0006301)3.30211789
88establishment of chromosome localization (GO:0051303)3.30114992
89regulation of centrosome duplication (GO:0010824)3.29608549
90DNA synthesis involved in DNA repair (GO:0000731)3.28923681
91protein complex localization (GO:0031503)3.28219479
92ATP-dependent chromatin remodeling (GO:0043044)3.27954468
93telomere organization (GO:0032200)3.27851029
94DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla3.26305577
95spindle checkpoint (GO:0031577)3.24705652
96DNA packaging (GO:0006323)3.22447253
97somatic diversification of immune receptors via somatic mutation (GO:0002566)3.22013289
98somatic hypermutation of immunoglobulin genes (GO:0016446)3.22013289
99regulation of translational fidelity (GO:0006450)3.17865368
100regulation of mitotic metaphase/anaphase transition (GO:0030071)3.17633741
101positive regulation of cell cycle checkpoint (GO:1901978)3.16850807
102peptidyl-lysine dimethylation (GO:0018027)3.15039405
103cellular protein complex localization (GO:0034629)3.14056776
104mitochondrial DNA metabolic process (GO:0032042)3.13752665
105regulation of mitotic spindle organization (GO:0060236)3.12744209
106peptidyl-arginine omega-N-methylation (GO:0035247)3.11023271
107V(D)J recombination (GO:0033151)3.10231116
108spindle assembly checkpoint (GO:0071173)3.09538263
109regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.09052752
110ribosomal small subunit assembly (GO:0000028)3.08809607
111proline biosynthetic process (GO:0006561)3.06842995
112positive regulation of histone methylation (GO:0031062)3.06750605
113replicative senescence (GO:0090399)3.04802711
114viral transcription (GO:0019083)3.02956874
115maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.02675232
116rRNA transcription (GO:0009303)3.02623025
117regulation of mitotic sister chromatid separation (GO:0010965)3.00801777
118regulation of mitotic sister chromatid segregation (GO:0033047)3.00801777
119regulation of sister chromatid segregation (GO:0033045)3.00801777
120nucleobase biosynthetic process (GO:0046112)3.00545352
121negative regulation of chromosome segregation (GO:0051985)3.00334757
122mitotic DNA integrity checkpoint (GO:0044774)3.00062609
123negative regulation of mitotic sister chromatid separation (GO:2000816)3.00059770
124negative regulation of sister chromatid segregation (GO:0033046)3.00059770
125negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.00059770
126negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.00059770
127negative regulation of mitotic sister chromatid segregation (GO:0033048)3.00059770
128translational termination (GO:0006415)2.99843294
129nucleobase-containing small molecule interconversion (GO:0015949)2.99686376
130mitotic spindle assembly checkpoint (GO:0007094)2.97179655
131regulation of spindle checkpoint (GO:0090231)2.95817953
132histone arginine methylation (GO:0034969)2.85607222
133mitotic spindle checkpoint (GO:0071174)2.83336003

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.25025480
2FOXM1_23109430_ChIP-Seq_U2OS_Human5.42898892
3E2F4_17652178_ChIP-ChIP_JURKAT_Human4.75055378
4HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.49787753
5BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.45295740
6FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.11621116
7* SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.78515711
8* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.63648498
9MYC_18555785_ChIP-Seq_MESCs_Mouse2.45493190
10* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.41572590
11* E2F1_21310950_ChIP-Seq_MCF-7_Human2.34116866
12NELFA_20434984_ChIP-Seq_ESCs_Mouse2.16393335
13* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.13252140
14* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.00225745
15* FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse12.0347533
16SOX2_16153702_ChIP-ChIP_HESCs_Human1.90778700
17AR_21909140_ChIP-Seq_LNCAP_Human1.89271111
18EGR1_19374776_ChIP-ChIP_THP-1_Human1.87764970
19* EGR1_23403033_ChIP-Seq_LIVER_Mouse1.80605941
20* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.80328779
21MYC_19079543_ChIP-ChIP_MESCs_Mouse1.79886917
22ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.66329586
23IRF1_19129219_ChIP-ChIP_H3396_Human1.59760443
24VDR_23849224_ChIP-Seq_CD4+_Human1.58265171
25CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.55773537
26SOX2_18555785_ChIP-Seq_MESCs_Mouse1.53837511
27* SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.52161889
28KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.51671158
29ESR1_15608294_ChIP-ChIP_MCF-7_Human1.49737887
30* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.47503456
31TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.46035418
32* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.45821766
33* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.43087351
34* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.42933184
35MYC_18358816_ChIP-ChIP_MESCs_Mouse1.40804096
36POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.39093895
37HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.38924109
38* KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.38077774
39KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.37862078
40ELK1_19687146_ChIP-ChIP_HELA_Human1.37018244
41POU5F1_16153702_ChIP-ChIP_HESCs_Human1.35275207
42POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.32239830
43MYC_22102868_ChIP-Seq_BL_Human1.27398806
44HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.24589667
45E2F1_18555785_ChIP-Seq_MESCs_Mouse1.23490172
46KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.22394988
47MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.20706033
48XRN2_22483619_ChIP-Seq_HELA_Human1.20423212
49NANOG_18555785_ChIP-Seq_MESCs_Mouse1.20300825
50IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.19225581
51STAT3_1855785_ChIP-Seq_MESCs_Mouse1.18374456
52* RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.16535645
53CREB1_15753290_ChIP-ChIP_HEK293T_Human1.16394520
54FOXP3_21729870_ChIP-Seq_TREG_Human1.14653891
55POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.14481842
56HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.14437248
57EST1_17652178_ChIP-ChIP_JURKAT_Human1.13194023
58PADI4_21655091_ChIP-ChIP_MCF-7_Human1.12482158
59THAP11_20581084_ChIP-Seq_MESCs_Mouse1.10873538
60NANOG_16153702_ChIP-ChIP_HESCs_Human1.10203121
61DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.09951655
62MYCN_18555785_ChIP-Seq_MESCs_Mouse1.09494560
63* SOX2_18692474_ChIP-Seq_MESCs_Mouse1.03702179
64SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.02640210
65BRD4_27068464_Chip-Seq_AML-cells_Mouse0.99631635
66TCF3_18692474_ChIP-Seq_MESCs_Mouse0.98764809
67CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.98729183
68ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.98578785
69MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.97866108
70* STAT4_19710469_ChIP-ChIP_TH1__Mouse0.97754112
71SALL1_21062744_ChIP-ChIP_HESCs_Human0.96897409
72RBPJ_22232070_ChIP-Seq_NCS_Mouse0.96323340
73ZFX_18555785_ChIP-Seq_MESCs_Mouse0.96021573
74ETS1_20019798_ChIP-Seq_JURKAT_Human0.96010114
75VDR_21846776_ChIP-Seq_THP-1_Human0.95933813
76CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.94942925
77NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.92814057
78YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.91540136
79GATA1_22025678_ChIP-Seq_K562_Human0.89017424
80NOTCH1_21737748_ChIP-Seq_TLL_Human0.87348732
81SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.86858492
82DCP1A_22483619_ChIP-Seq_HELA_Human0.86574653
83HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.86057381
84* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.85876893
85PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.84741123
86CIITA_25753668_ChIP-Seq_RAJI_Human0.84079681
87GABP_17652178_ChIP-ChIP_JURKAT_Human0.83738419
88TTF2_22483619_ChIP-Seq_HELA_Human0.82871916
89SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.82649416
90ETS1_22383799_ChIP-Seq_G1ME_Mouse0.80295899
91VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.79578728
92KDM5A_27292631_Chip-Seq_BREAST_Human0.79006384
93ELF1_17652178_ChIP-ChIP_JURKAT_Human0.78777955
94PKCTHETA_26484144_Chip-Seq_BREAST_Human0.77619377
95GATA2_22383799_ChIP-Seq_G1ME_Mouse0.74803508
96TP63_17297297_ChIP-ChIP_HaCaT_Human0.74770649
97FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.74446342
98STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.73992716
99SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.73002869
100NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.72499336
101MAF_26560356_Chip-Seq_TH1_Human0.72358272
102E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.72295031
103MYC_18940864_ChIP-ChIP_HL60_Human0.71975584
104CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.71905148
105ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.71642582
106NANOG_21062744_ChIP-ChIP_HESCs_Human0.71025725
107JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.69221702
108PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.68864408
109KLF4_18555785_ChIP-Seq_MESCs_Mouse0.68145195
110GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.67997705
111ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.67410874
112FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.67293363
113ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.66603025
114CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.65059159
115SOX17_20123909_ChIP-Seq_XEN_Mouse0.64821422

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability5.28429039
2MP0003111_abnormal_nucleus_morphology4.56128208
3MP0003693_abnormal_embryo_hatching4.29969264
4MP0003077_abnormal_cell_cycle4.02790065
5MP0010307_abnormal_tumor_latency3.79188195
6MP0004957_abnormal_blastocyst_morpholog3.53412238
7MP0008057_abnormal_DNA_replication3.46053544
8MP0010352_gastrointestinal_tract_polyps2.80969368
9MP0008058_abnormal_DNA_repair2.76541410
10MP0003656_abnormal_erythrocyte_physiolo2.73817992
11MP0004147_increased_porphyrin_level2.49488242
12MP0000350_abnormal_cell_proliferation2.38737420
13MP0005076_abnormal_cell_differentiation2.35884085
14MP0008007_abnormal_cellular_replicative2.31742650
15MP0008932_abnormal_embryonic_tissue2.22394718
16MP0003705_abnormal_hypodermis_morpholog2.22019065
17MP0001661_extended_life_span2.17851788
18MP0002396_abnormal_hematopoietic_system2.17252412
19MP0006054_spinal_hemorrhage2.16500135
20MP0001730_embryonic_growth_arrest2.16344861
21MP0009697_abnormal_copulation2.07040726
22MP0003123_paternal_imprinting2.05831908
23MP0004185_abnormal_adipocyte_glucose2.04190829
24MP0004808_abnormal_hematopoietic_stem1.95567913
25MP0003763_abnormal_thymus_physiology1.88570468
26MP0000490_abnormal_crypts_of1.87289673
27MP0008877_abnormal_DNA_methylation1.71452270
28MP0004197_abnormal_fetal_growth/weight/1.70456963
29MP0001697_abnormal_embryo_size1.67811871
30MP0003121_genomic_imprinting1.67402632
31MP0002086_abnormal_extraembryonic_tissu1.66428667
32MP0001672_abnormal_embryogenesis/_devel1.64887159
33MP0005380_embryogenesis_phenotype1.64887159
34MP0002019_abnormal_tumor_incidence1.59598094
35MP0003941_abnormal_skin_development1.58565252
36MP0002080_prenatal_lethality1.55066012
37MP0010234_abnormal_vibrissa_follicle1.52441842
38MP0005623_abnormal_meninges_morphology1.51762544
39MP0002085_abnormal_embryonic_tissue1.50739135
40MP0002084_abnormal_developmental_patter1.49857047
41MP0003984_embryonic_growth_retardation1.45119233
42MP0002088_abnormal_embryonic_growth/wei1.43090563
43MP0003786_premature_aging1.42265337
44MP0000313_abnormal_cell_death1.41716296
45MP0006035_abnormal_mitochondrial_morpho1.38762419
46MP0005645_abnormal_hypothalamus_physiol1.35917228
47MP0000703_abnormal_thymus_morphology1.33308291
48MP0005220_abnormal_exocrine_pancreas1.31292977
49MP0001293_anophthalmia1.29481262
50MP0002163_abnormal_gland_morphology1.28423697
51MP0002398_abnormal_bone_marrow1.24782971
52MP0002722_abnormal_immune_system1.19971854
53MP0002877_abnormal_melanocyte_morpholog1.17652035
54MP0005397_hematopoietic_system_phenotyp1.16199309
55MP0001545_abnormal_hematopoietic_system1.16199309
56MP0000689_abnormal_spleen_morphology1.11168510
57MP0002095_abnormal_skin_pigmentation1.10804874
58MP0001346_abnormal_lacrimal_gland1.10804411
59MP0002166_altered_tumor_susceptibility1.10451847
60MP0001915_intracranial_hemorrhage1.08075450
61MP0004233_abnormal_muscle_weight1.06626425
62MP0005451_abnormal_body_composition1.04639620
63MP0003567_abnormal_fetal_cardiomyocyte1.04366497
64MP0000537_abnormal_urethra_morphology1.02282343
65MP0003937_abnormal_limbs/digits/tail_de0.97725857
66MP0003566_abnormal_cell_adhesion0.97486789
67MP0002092_abnormal_eye_morphology0.95870166
68MP0002006_tumorigenesis0.95300628
69MP0002009_preneoplasia0.95261435
70MP0000733_abnormal_muscle_development0.91573543
71MP0002429_abnormal_blood_cell0.90658678
72MP0001727_abnormal_embryo_implantation0.90076166
73MP0002111_abnormal_tail_morphology0.89996922
74MP0003300_gastrointestinal_ulcer0.89545767
75MP0008770_decreased_survivor_rate0.89094758
76MP0003890_abnormal_embryonic-extraembry0.88697570
77MP0002697_abnormal_eye_size0.85890963
78MP0003806_abnormal_nucleotide_metabolis0.85744380
79MP0005621_abnormal_cell_physiology0.85706552
80MP0003787_abnormal_imprinting0.85508689
81MP0009703_decreased_birth_body0.85300435
82MP0005384_cellular_phenotype0.84173284
83MP0003448_altered_tumor_morphology0.83469487
84MP0005023_abnormal_wound_healing0.82007176
85MP0009053_abnormal_anal_canal0.81959373
86MP0002075_abnormal_coat/hair_pigmentati0.81422568
87MP0000015_abnormal_ear_pigmentation0.78674792
88MP0009672_abnormal_birth_weight0.75524057
89MP0000371_diluted_coat_color0.75308070
90MP0002160_abnormal_reproductive_system0.74899430
91MP0000428_abnormal_craniofacial_morphol0.71649496
92MP0001800_abnormal_humoral_immune0.71312601
93MP0000013_abnormal_adipose_tissue0.70511978
94MP0000716_abnormal_immune_system0.70413210
95MP0005501_abnormal_skin_physiology0.69699332
96MP0002210_abnormal_sex_determination0.69528867
97MP0000372_irregular_coat_pigmentation0.69015232
98MP0003221_abnormal_cardiomyocyte_apopto0.68964708
99MP0002925_abnormal_cardiovascular_devel0.68548927
100MP0003385_abnormal_body_wall0.68285925
101MP0001145_abnormal_male_reproductive0.67549104
102MP0003315_abnormal_perineum_morphology0.66992049
103MP0000685_abnormal_immune_system0.65910498
104MP0009278_abnormal_bone_marrow0.65790328
105MP0000003_abnormal_adipose_tissue0.65577144
106MP0001835_abnormal_antigen_presentation0.65172156
107MP0000358_abnormal_cell_content/0.64077307
108MP0000477_abnormal_intestine_morphology0.63321550
109MP0001929_abnormal_gametogenesis0.62939177
110MP0003303_peritoneal_inflammation0.62269800
111MP0000858_altered_metastatic_potential0.61266056
112MP0003699_abnormal_female_reproductive0.60753970
113MP0001286_abnormal_eye_development0.60001979
114MP0010678_abnormal_skin_adnexa0.59724564
115MP0001191_abnormal_skin_condition0.59354638
116MP0002452_abnormal_antigen_presenting0.59121340
117MP0001849_ear_inflammation0.58083041
118MP0001186_pigmentation_phenotype0.57351393
119MP0005083_abnormal_biliary_tract0.57124816
120MP0005310_abnormal_salivary_gland0.56869081
121MP0003453_abnormal_keratinocyte_physiol0.56642616
122MP0010030_abnormal_orbit_morphology0.56470701
123MP0000747_muscle_weakness0.56029732
124MP0009333_abnormal_splenocyte_physiolog0.55800540
125MP0000653_abnormal_sex_gland0.54408648
126MP0002420_abnormal_adaptive_immunity0.54192786
127MP0001119_abnormal_female_reproductive0.53816450
128MP0003718_maternal_effect0.53497584
129MP0005171_absent_coat_pigmentation0.53092406
130MP0005391_vision/eye_phenotype0.52105228

Predicted human phenotypes

RankGene SetZ-score
1IgA deficiency (HP:0002720)5.17018087
2IgM deficiency (HP:0002850)5.10900878
3Poikilocytosis (HP:0004447)4.78487515
4Chromsome breakage (HP:0040012)4.49688638
5Chromosomal breakage induced by crosslinking agents (HP:0003221)4.29704236
6Reticulocytopenia (HP:0001896)4.01111736
7Colitis (HP:0002583)3.95204366
8Abnormality of chromosome stability (HP:0003220)3.84160370
9Hypochromic microcytic anemia (HP:0004840)3.82965870
10Abnormality of the heme biosynthetic pathway (HP:0010472)3.81250438
11Birth length less than 3rd percentile (HP:0003561)3.32612802
12Microvesicular hepatic steatosis (HP:0001414)3.27899923
13Ependymoma (HP:0002888)3.19201785
14Impulsivity (HP:0100710)3.14165160
15Acanthocytosis (HP:0001927)3.14119719
16Abnormality of reticulocytes (HP:0004312)3.09032370
17Medulloblastoma (HP:0002885)3.04134969
18Agnosia (HP:0010524)3.02361674
19Cutaneous melanoma (HP:0012056)3.00382814
20Aplasia/Hypoplasia of the uvula (HP:0010293)2.93483077
21Meckel diverticulum (HP:0002245)2.91657310
22Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.89974016
23Short 4th metacarpal (HP:0010044)2.89974016
24Abnormality of cells of the erythroid lineage (HP:0012130)2.88412732
25Gastrointestinal stroma tumor (HP:0100723)2.86349533
26Colon cancer (HP:0003003)2.84097867
27Selective tooth agenesis (HP:0001592)2.83878249
28Rhabdomyosarcoma (HP:0002859)2.82844015
29Volvulus (HP:0002580)2.81358764
30Duodenal stenosis (HP:0100867)2.77032206
31Small intestinal stenosis (HP:0012848)2.77032206
32Abnormality of the ileum (HP:0001549)2.77029027
33Abnormality of the labia minora (HP:0012880)2.75761332
34Basal cell carcinoma (HP:0002671)2.75258677
35Abnormality of the preputium (HP:0100587)2.74075747
36Cafe-au-lait spot (HP:0000957)2.70367596
37Aplasia/Hypoplasia of the sacrum (HP:0008517)2.68961676
38High pitched voice (HP:0001620)2.64944933
39Cellulitis (HP:0100658)2.62318572
40Abnormal number of erythroid precursors (HP:0012131)2.60470924
41Reticulocytosis (HP:0001923)2.57237726
42Astrocytoma (HP:0009592)2.56307031
43Abnormality of the astrocytes (HP:0100707)2.56307031
44Increased nuchal translucency (HP:0010880)2.53194816
45Myelodysplasia (HP:0002863)2.51986918
46Prominent nose (HP:0000448)2.51979746
47Embryonal renal neoplasm (HP:0011794)2.51489643
48Sloping forehead (HP:0000340)2.39416247
49Patellar aplasia (HP:0006443)2.39332456
50Abnormality of the carotid arteries (HP:0005344)2.35660434
51Abnormality of DNA repair (HP:0003254)2.35278568
52Ectopic kidney (HP:0000086)2.32242338
53Sandal gap (HP:0001852)2.31476206
54Glioma (HP:0009733)2.29875336
55Biliary tract neoplasm (HP:0100574)2.29732532
56Macrocytic anemia (HP:0001972)2.28559157
57Abnormality of the duodenum (HP:0002246)2.26240917
58Abnormal number of incisors (HP:0011064)2.24919923
59B lymphocytopenia (HP:0010976)2.24617321
60Pallor (HP:0000980)2.24186513
61Progressive external ophthalmoplegia (HP:0000590)2.23560010
62Orthostatic hypotension (HP:0001278)2.22866971
63Neoplasm of the oral cavity (HP:0100649)2.22314215
64Deviation of the thumb (HP:0009603)2.21714801
6511 pairs of ribs (HP:0000878)2.21427610
66Freckling (HP:0001480)2.18984725
67Hypopigmentation of the fundus (HP:0007894)2.18793188
68Proximal placement of thumb (HP:0009623)2.18643646
69Abnormality of pyrimidine metabolism (HP:0004353)2.17746970
70Absent thumb (HP:0009777)2.17591892
71Abnormality of cochlea (HP:0000375)2.16593447
72Aplasia/Hypoplasia of the patella (HP:0006498)2.15742146
73Squamous cell carcinoma (HP:0002860)2.12341139
74Insomnia (HP:0100785)2.10397833
75Recurrent sinusitis (HP:0011108)2.10321035
76Progressive muscle weakness (HP:0003323)2.09192751
77Duplicated collecting system (HP:0000081)2.08492980
78Asymmetry of the thorax (HP:0001555)2.08490983
79Neoplasm of striated muscle (HP:0009728)2.08260817
80Ureteral duplication (HP:0000073)2.08003569
81Neoplasm of the pancreas (HP:0002894)2.05614479
82Dry hair (HP:0011359)2.05424184
83Amaurosis fugax (HP:0100576)2.03151192
84Absent radius (HP:0003974)2.01482651
85Gastrointestinal carcinoma (HP:0002672)2.01129469
86Malignant gastrointestinal tract tumors (HP:0006749)2.01129469
87Abnormality of the fingertips (HP:0001211)2.01114110
88Hypochromic anemia (HP:0001931)2.01049541
89Acute lymphatic leukemia (HP:0006721)2.00323767
90Cortical dysplasia (HP:0002539)1.99919369
91Abnormality of cells of the lymphoid lineage (HP:0012140)1.99605742
92Agammaglobulinemia (HP:0004432)1.98006866
93Hypergonadotropic hypogonadism (HP:0000815)1.96583697
94Inflammation of the large intestine (HP:0002037)1.95585475
95Entropion (HP:0000621)1.95029463
96Hypoplasia of the pons (HP:0012110)1.92366749
97Arteriovenous malformation (HP:0100026)1.90989601
98Abnormality of B cell number (HP:0010975)1.90767742
99Lymphopenia (HP:0001888)1.90715488
100Abnormal lung lobation (HP:0002101)1.90017396
101Hypoplasia of the capital femoral epiphysis (HP:0003090)1.88904972
102Ovarian neoplasm (HP:0100615)1.87651867
103Abnormality of the 4th metacarpal (HP:0010012)1.87079433
104Clubbing of toes (HP:0100760)1.87041727
105Lymphoma (HP:0002665)1.86750446
106Short thumb (HP:0009778)1.86733328
107Missing ribs (HP:0000921)1.85455973
108Hyperacusis (HP:0010780)1.85294765
109Atresia of the external auditory canal (HP:0000413)1.84179341
110Gastrointestinal inflammation (HP:0004386)1.84045919
111Absent forearm bone (HP:0003953)1.83333447
112Aplasia involving forearm bones (HP:0009822)1.83333447
113Deep palmar crease (HP:0006191)1.82596424
114Bone marrow hypocellularity (HP:0005528)1.82107982
115Poikiloderma (HP:0001029)1.81258031
116Cutis marmorata (HP:0000965)1.81133332
117Breast hypoplasia (HP:0003187)1.79965104
118Subacute progressive viral hepatitis (HP:0006572)1.79777963
119Embryonal neoplasm (HP:0002898)1.78324709
120Duplication of thumb phalanx (HP:0009942)1.78289106
121Nephroblastoma (Wilms tumor) (HP:0002667)1.78122035
122Verrucae (HP:0200043)1.78108499
123Papilloma (HP:0012740)1.78108499
124Spastic diplegia (HP:0001264)1.77493130
125Abnormality of the distal phalanx of the thumb (HP:0009617)1.77001138
126Lipid accumulation in hepatocytes (HP:0006561)1.75213126
127Abnormality of the pons (HP:0007361)1.75001701
128Deep philtrum (HP:0002002)1.74796011
129High anterior hairline (HP:0009890)1.74602013
130Broad distal phalanx of finger (HP:0009836)1.74527635
131Leukopenia (HP:0001882)1.73745290
132Thrombocytosis (HP:0001894)1.73672227
133Hepatitis (HP:0012115)1.73637591
134Tracheoesophageal fistula (HP:0002575)1.73319549
135Abnormality of the renal collecting system (HP:0004742)1.72850571
136Oral leukoplakia (HP:0002745)1.72777332
137Rough bone trabeculation (HP:0100670)1.72737844
138Abnormality of chromosome segregation (HP:0002916)1.72454771
139Ankyloglossia (HP:0010296)1.72081828
140Skull defect (HP:0001362)1.71636132
141Thyroiditis (HP:0100646)1.71619538
142Leiomyosarcoma (HP:0100243)1.71599307
143Uterine leiomyosarcoma (HP:0002891)1.71599307
144Heterotopia (HP:0002282)1.71578725
145Aplasia/Hypoplasia of the sternum (HP:0006714)1.71355559
146Abnormality of the calcaneus (HP:0008364)1.70987294
147Erythema (HP:0010783)1.70138117
148Viral hepatitis (HP:0006562)1.69902905
149Down-sloping shoulders (HP:0200021)1.68832299
150Recurrent bronchitis (HP:0002837)1.65916543
151Autoimmune hemolytic anemia (HP:0001890)1.65286537

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TLK19.04855801
2ZAK5.92009967
3VRK13.65276588
4CDC73.64888184
5STK43.44696930
6WEE12.53672035
7NEK22.33151604
8MAP3K102.24127693
9SCYL22.03509585
10CDK122.00785832
11BUB11.97911852
12AURKB1.86184307
13MAP3K81.76261708
14* RPS6KA51.75316230
15SRPK11.72457848
16PIM11.70394815
17EIF2AK11.66166150
18CDK91.65358718
19CHEK21.59764657
20SMG11.58690846
21EEF2K1.51678254
22TTK1.48010946
23NEK11.45858311
24PKN21.40688329
25TRIB31.34588121
26PLK11.27227454
27RPS6KB21.26976353
28DYRK31.23744315
29ATR1.22943486
30CDK41.09340180
31ACVR1B1.07357081
32TAF11.06847459
33AURKA1.05557430
34BRSK21.05168165
35GRK61.01006512
36STK100.97350939
37DAPK30.94030653
38NME20.91246841
39EIF2AK30.88951228
40PLK30.88657680
41EPHA20.88451059
42ICK0.87173693
43FLT30.85548506
44CHEK10.84715866
45CDK70.82010863
46PKN10.79601509
47PASK0.78926749
48CDK60.77581056
49ATM0.77422914
50TTN0.73620054
51MELK0.71955671
52BRSK10.70220738
53PLK40.68592504
54CDK80.66841204
55CDK20.65760308
56BRAF0.65428908
57CAMK1D0.64705467
58CCNB10.62715921
59BRD40.61539880
60MAP2K70.60946226
61DYRK1B0.60228174
62STK30.59102314
63STK160.56528670
64MAPK110.56138947
65AKT20.55818007
66MAP3K40.53645319
67CDK10.52440602
68LRRK20.48575681
69RPS6KA40.47666533
70EIF2AK20.46099682
71TSSK60.46029707
72BLK0.45688794
73IRAK30.44914132
74PIM20.42555232
75PRKAA10.42439305
76PBK0.40348847
77BTK0.40107152
78CSNK1D0.39844006
79CSNK1G30.39484087
80KDR0.39328766
81CSNK1G10.38696051
82TESK20.37075183
83MKNK10.36913231
84CSNK1A1L0.36036767
85TGFBR10.35123437
86PRPF4B0.34813689
87CAMK40.34251773
88MAP2K30.33985464
89PAK40.33959244
90NEK90.33214927
91PAK10.32686170
92FRK0.32451616
93MAP2K40.32381607
94MARK30.31024983
95PRKDC0.30583125
96MTOR0.30194111
97IRAK40.29415739
98KSR10.29263303
99RAF10.29107233
100CLK10.26914545
101JAK20.26416117
102CSNK2A20.24409613
103MET0.23162648
104MAPK140.23152632
105ALK0.22089446
106AKT10.21126011
107MAP4K10.19324605
108CAMKK20.19133108
109BMX0.18162112
110CSF1R0.17505567
111RPS6KB10.17306604
112MAPKAPK50.16982569
113CSNK2A10.15340852
114MKNK20.13494025
115TRPM70.13374769
116CSNK1G20.12130418
117ILK0.11600220
118PAK20.11428216
119BCKDK0.11369315
120LYN0.11298573
121LATS10.10976393
122PRKCI0.10515660
123SYK0.10068790
124MAPK10.09934681
125ROCK10.09709892
126PRKCQ0.09498846
127RPS6KL10.08634261
128RPS6KC10.08634261
129FGFR20.08535271
130ARAF0.08330753
131ERBB20.08073755
132GSK3B0.07712017
133MAPKAPK30.07357035
134MAP2K20.05739756
135RPS6KA10.04747216
136MST1R0.04513215
137RET0.04238447

Predicted pathways (KEGG)

RankGene SetZ-score
1* Alcoholism_Homo sapiens_hsa050345.71629606
2DNA replication_Homo sapiens_hsa030303.78293241
3Mismatch repair_Homo sapiens_hsa034303.20159926
4Viral carcinogenesis_Homo sapiens_hsa052033.17536512
5Cell cycle_Homo sapiens_hsa041102.34226841
6One carbon pool by folate_Homo sapiens_hsa006702.22057626
7Base excision repair_Homo sapiens_hsa034102.08905699
8Homologous recombination_Homo sapiens_hsa034402.02622815
9* Systemic lupus erythematosus_Homo sapiens_hsa0532210.2084680
10Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.97578040
11Nucleotide excision repair_Homo sapiens_hsa034201.95743148
12Non-homologous end-joining_Homo sapiens_hsa034501.95339677
13Fanconi anemia pathway_Homo sapiens_hsa034601.89130847
14RNA transport_Homo sapiens_hsa030131.84040389
15Spliceosome_Homo sapiens_hsa030401.75724448
16Transcriptional misregulation in cancer_Homo sapiens_hsa052021.69112023
17Ribosome_Homo sapiens_hsa030101.67309496
18Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.62036379
19p53 signaling pathway_Homo sapiens_hsa041151.33618520
20Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.21696795
21Pyrimidine metabolism_Homo sapiens_hsa002401.20180138
22mRNA surveillance pathway_Homo sapiens_hsa030151.08582380
23MicroRNAs in cancer_Homo sapiens_hsa052060.94522445
24RNA polymerase_Homo sapiens_hsa030200.92668256
25RNA degradation_Homo sapiens_hsa030180.92032986
26Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.85427281
27Small cell lung cancer_Homo sapiens_hsa052220.83134712
28Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.82623658
29Oocyte meiosis_Homo sapiens_hsa041140.74528360
30Herpes simplex infection_Homo sapiens_hsa051680.74010148
31HTLV-I infection_Homo sapiens_hsa051660.69773189
32Epstein-Barr virus infection_Homo sapiens_hsa051690.68726381
33Chronic myeloid leukemia_Homo sapiens_hsa052200.66956789
34Selenocompound metabolism_Homo sapiens_hsa004500.66899582
35Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.66211152
36Antigen processing and presentation_Homo sapiens_hsa046120.65158887
37Proteasome_Homo sapiens_hsa030500.60067836
38Basal transcription factors_Homo sapiens_hsa030220.55956587
39Apoptosis_Homo sapiens_hsa042100.55260157
40Non-small cell lung cancer_Homo sapiens_hsa052230.54773916
41Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.52417441
42Hepatitis B_Homo sapiens_hsa051610.50255995
43Bladder cancer_Homo sapiens_hsa052190.50226441
44Purine metabolism_Homo sapiens_hsa002300.45981093
45Colorectal cancer_Homo sapiens_hsa052100.41666099
46Carbon metabolism_Homo sapiens_hsa012000.41132234
47Hematopoietic cell lineage_Homo sapiens_hsa046400.40922917
48NF-kappa B signaling pathway_Homo sapiens_hsa040640.39393114
49Measles_Homo sapiens_hsa051620.38366019
50mTOR signaling pathway_Homo sapiens_hsa041500.37233423
51Pancreatic cancer_Homo sapiens_hsa052120.36528290
52Pentose phosphate pathway_Homo sapiens_hsa000300.36519615
53Asthma_Homo sapiens_hsa053100.36100029
54Allograft rejection_Homo sapiens_hsa053300.35979146
55Fructose and mannose metabolism_Homo sapiens_hsa000510.35935766
56Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.34905704
57Legionellosis_Homo sapiens_hsa051340.34303062
58Lysine degradation_Homo sapiens_hsa003100.33902701
59Autoimmune thyroid disease_Homo sapiens_hsa053200.33649942
602-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.33481453
61Central carbon metabolism in cancer_Homo sapiens_hsa052300.33134662
62Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.32988532
63Prostate cancer_Homo sapiens_hsa052150.32756256
64Galactose metabolism_Homo sapiens_hsa000520.31865533
65B cell receptor signaling pathway_Homo sapiens_hsa046620.31152564
66Malaria_Homo sapiens_hsa051440.30584362
67Renin-angiotensin system_Homo sapiens_hsa046140.30072774
68Biosynthesis of amino acids_Homo sapiens_hsa012300.29992709
69TGF-beta signaling pathway_Homo sapiens_hsa043500.29480131
70FoxO signaling pathway_Homo sapiens_hsa040680.28474668
71Glioma_Homo sapiens_hsa052140.27626699
72Thyroid cancer_Homo sapiens_hsa052160.27569645
73Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.27220858
74Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.26917737
75Melanoma_Homo sapiens_hsa052180.26343034
76Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.26189300
77Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.25592581
78Sulfur relay system_Homo sapiens_hsa041220.24872944
79Drug metabolism - other enzymes_Homo sapiens_hsa009830.24686817
80Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.23996928
81Notch signaling pathway_Homo sapiens_hsa043300.23073080
82Inositol phosphate metabolism_Homo sapiens_hsa005620.22723990
83Viral myocarditis_Homo sapiens_hsa054160.22698046
84Primary immunodeficiency_Homo sapiens_hsa053400.22681254
85Influenza A_Homo sapiens_hsa051640.22503479
86Proteoglycans in cancer_Homo sapiens_hsa052050.22414015
87Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.21933953
88Graft-versus-host disease_Homo sapiens_hsa053320.20589045
89Arginine biosynthesis_Homo sapiens_hsa002200.19254557
90Pathways in cancer_Homo sapiens_hsa052000.19212978
91Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.18013024
92HIF-1 signaling pathway_Homo sapiens_hsa040660.17425111
93Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.15744323
94Pyruvate metabolism_Homo sapiens_hsa006200.15688142
95Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.15622258
96Adherens junction_Homo sapiens_hsa045200.15261425
97Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.14928174
98Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.14746006
99Hippo signaling pathway_Homo sapiens_hsa043900.14218245
100Cysteine and methionine metabolism_Homo sapiens_hsa002700.13519410
101RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.13399920
102Basal cell carcinoma_Homo sapiens_hsa052170.13373561
103Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.13130825
104Endometrial cancer_Homo sapiens_hsa052130.12840096
105Cyanoamino acid metabolism_Homo sapiens_hsa004600.12760090
106Leishmaniasis_Homo sapiens_hsa051400.12397798
107Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.12309917
108NOD-like receptor signaling pathway_Homo sapiens_hsa046210.11694609
109Type I diabetes mellitus_Homo sapiens_hsa049400.11683199
110Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.11360725
111Thyroid hormone signaling pathway_Homo sapiens_hsa049190.11187957
112Toxoplasmosis_Homo sapiens_hsa051450.10566685
113Folate biosynthesis_Homo sapiens_hsa007900.10228918
114Leukocyte transendothelial migration_Homo sapiens_hsa046700.10043164
115Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.09761718
116Acute myeloid leukemia_Homo sapiens_hsa052210.09538001
117PI3K-Akt signaling pathway_Homo sapiens_hsa041510.08678618
118Intestinal immune network for IgA production_Homo sapiens_hsa046720.08388012
119N-Glycan biosynthesis_Homo sapiens_hsa005100.07566626
120Platelet activation_Homo sapiens_hsa046110.07155808
121Focal adhesion_Homo sapiens_hsa045100.07014201
122Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.06846505
123Hedgehog signaling pathway_Homo sapiens_hsa043400.06756453
124Vitamin B6 metabolism_Homo sapiens_hsa007500.06715874
125Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.06710620
126ErbB signaling pathway_Homo sapiens_hsa040120.06294233
127Longevity regulating pathway - mammal_Homo sapiens_hsa042110.05300235
128Sulfur metabolism_Homo sapiens_hsa009200.05277640

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »